ZYME Zymeworks Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$24.90
Price · May 20, 2026
Fundamentals as of May 7, 2026

ZYME Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$24.89
Market Cap
$1.97B
P/E (TTM)
-24.4
EPS (TTM)
$-1.08
Revenue (TTM)
$106M
Div Yield
ROE
-26.9%
Debt/Equity
52W Range
$11 – $30

ZYME Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $106M
6-point trend, +172.0%
2020-12-31 2025-12-31
EPS $-1.08
6-point trend, +69.8%
2020-12-31 2025-12-31
Free Cash Flow $-35M
3-point trend, +71.4%
2023-12-31 2025-12-31
Margins -76.6%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ZYME
Peer Median
P/E (TTM)
4-point trend, -689.3%
-24.4
11.3
P/S (TTM)
3-point trend, +93.5%
18.5
22.0
P/B
3-point trend, +367.0%
7.3
6.3
Price / FCF
3-point trend, -843.7%
-56.9

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ZYME
Peer Median
Operating Margin
3-point trend, +51.9%
-87.3%
Net Profit Margin
3-point trend, +51.0%
-76.6%
-74.2%
ROA
3-point trend, -3.8%
-20.0%
-30.3%
ROE
3-point trend, -0.8%
-26.9%
-42.3%
ROIC
3-point trend, -18.6%
-35.1%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ZYME
Peer Median
Current Ratio
3-point trend, -20.6%
5.9
8.0
Quick Ratio
3-point trend, -84.7%
1.1

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ZYME
Peer Median
Revenue YoY
5-point trend, +297.2%
38.9%
Revenue CAGR 3Y
5-point trend, +297.2%
-36.4%
Revenue CAGR 5Y
5-point trend, +297.2%
22.2%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ZYME
Peer Median
EPS (Diluted)
5-point trend, +76.6%
$-1.08

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ZYME
Peer Median

ZYME Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 20 analysts
  • Strong Buy 6 30.0%
  • Buy 13 65.0%
  • Hold 1 5.0%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

13 analysts · 2026-05-17
Median target $40.00 +60.7%
Mean target $40.15 +61.3%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.04%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.59 $-0.20 -0.39%
Dec. 31, 2025 $-0.55 $-0.42 -0.13%
Sept. 30, 2025 $-0.26 $-0.33 0.07%
June 30, 2025 $0.03 $-0.50 0.53%
March 31, 2025 $-0.30 $-0.42 0.12%

Peer Comparison Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ZYME $1.97B -24.4 38.9% -76.6% -26.9%
AUPH $2.11B 7.7 20.4% 101.5% 62.7%
ABUS $926M -28.3 128.2% -237.9% -42.0%
ACOG $141M -5.5 -202.2% -43.8%
XENE $3.59B -10.3 -4612.1% -56.9%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for ZYME
Metric Trend 20252024202320222021
Revenue 5-point trend, +297.2% $106M $76M $76M $412M $27M
R&D Expense 3-point trend, -28.1% · · $144M $209M $200M
SG&A Expense 5-point trend, +44.5% $62M $62M $70M $73M $43M
Operating Expenses 5-point trend, -18.1% $199M $213M $214M $282M $242M
Operating Income 5-point trend, +57.1% $-93M $-137M $-138M $131M $-216M
Other Non-op 5-point trend, -56.8% $51.0K $-218.0K $291.0K $-42.0K $118.0K
Pretax Income 5-point trend, +62.4% $-80M $-117M $-119M $135M $-212M
Income Tax 5-point trend, +366.7% $1M $6M $-568.0K $11M $-516.0K
Net Income 5-point trend, +61.7% $-81M $-123M $-119M $124M $-212M
EPS (Basic) 5-point trend, +73.7% $-1.08 $-1.62 $-1.72 $1.91 $-4.11
EPS (Diluted) 5-point trend, +76.6% $-1.08 $-1.62 $-1.72 $1.90 $-4.61
Shares (Basic) 5-point trend, +46.3% 75,404,897 75,846,681 68,863,010 65,194,775 51,553,869
Shares (Diluted) 5-point trend, +44.7% 75,413,396 75,878,738 68,863,010 65,249,184 52,131,596
EBITDA 3-point trend, +33.0% $-93M $-137M $-138M · ·
Balance Sheet 23
Annual Balance Sheet data for ZYME
Metric Trend 20252024202320222021
Cash & Equivalents 5-point trend, -79.6% $41M $66M $158M $401M $202M
Short-term Investments 3-point trend, +327.2% · · $217M $91M $51M
Receivables 5-point trend, -70.3% $5M $56M $19M $33M $16M
Prepaid Expense 5-point trend, -23.3% $15M $19M $19M $19M $20M
Current Assets 5-point trend, -13.7% $249M $300M $413M $545M $288M
PP&E (Net) 5-point trend, -32.0% $16M $18M $20M $25M $23M
PP&E (Gross) 5-point trend, -1.3% $36M $35M $41M $38M $37M
Accum. Depreciation 5-point trend, +48.5% $21M $18M $21M $13M $14M
Goodwill Flat — no change across 5 periods $12M $12M $12M $12M $12M
Intangibles 5-point trend, -64.8% $1M $5M $8M $9M $4M
Total Assets 5-point trend, -10.9% $347M $463M $581M $649M $389M
Accounts Payable 5-point trend, -42.1% $36M $60M $46M $87M $63M
Current Liabilities 5-point trend, -41.1% $42M $88M $56M $96M $72M
Capital Leases 5-point trend, -52.2% $15M $16M $22M $25M $31M
Deferred Tax 5-point trend, +283.2% $6M $5M $3M $2M $2M
Other Non-current Liabilities 5-point trend, -89.9% $278.0K $923.0K $2M $3M $3M
Total Liabilities 5-point trend, -44.3% $78M $124M $116M $156M $140M
Common Stock 5-point trend, +49.1% $1.11B $1.02B $997M $886M $741M
Retained Earnings 5-point trend, -39.5% $-953M $-830M $-677M $-559M $-683M
AOCI 5-point trend, +8.7% $-6M $-7M $-7M $-7M $-7M
Stockholders' Equity 5-point trend, +7.8% $269M $339M $465M $493M $249M
Liabilities + Equity 5-point trend, -10.9% $347M $463M $581M $649M $389M
Shares Outstanding 5-point trend, +60.1% 74,638,413 68,964,319 70,115,997 63,059,501 46,633,935
Cash Flow 14
Annual Cash Flow data for ZYME
Metric Trend 20252024202320222021
Stock-based Comp 5-point trend, +160.6% $28M $18M $8M $4M $11M
Deferred Tax 5-point trend, +199.2% $945.0K $691.0K $-757.0K $2M $-953.0K
Amort. of Intangibles 5-point trend, +45.2% $4M $4M $3M $1M $3M
Restructuring · · $0 · ·
Operating Cash Flow 5-point trend, +82.9% $-33M $-110M $-118M $144M $-192M
CapEx 5-point trend, -87.7% $2M $2M $2M $8M $12M
Investing Cash Flow 5-point trend, -81.6% $27M $39M $-207M $-54M $145M
Stock Issued 5-point trend, +0.00 $0 $0 $26M $108M $0
Stock Repurchased 4-point trend, +41695000.00 $42M $30M $0 $0 ·
Net Stock Activity 3-point trend, -258.9% $-42M $-30M $26M · ·
Financing Cash Flow 5-point trend, -331.7% $-19M $-20M $82M $109M $8M
Net Change in Cash 5-point trend, +37.9% $-25M $-91M $-243M $199M $-40M
Taxes Paid 4-point trend, -86.5% $1M $3M $165.0K $10M ·
Free Cash Flow 3-point trend, +71.4% $-35M $-112M $-121M · ·
Profitability 7
Annual Profitability data for ZYME
Metric Trend 20252024202320222021
Operating Margin 3-point trend, +51.9% -87.3% -179.7% -181.6% · ·
Net Margin 3-point trend, +51.0% -76.6% -160.8% -156.1% · ·
Pretax Margin 3-point trend, +52.0% -75.3% -152.8% -156.9% · ·
EBITDA Margin 3-point trend, +51.9% -87.3% -179.7% -181.6% · ·
ROA 3-point trend, -3.8% -20.0% -23.5% -19.3% · ·
ROE 3-point trend, -0.8% -26.9% -34.8% -26.7% · ·
ROIC 3-point trend, -18.6% -35.1% -42.6% -29.6% · ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for ZYME
Metric Trend 20252024202320222021
Current Ratio 3-point trend, -20.6% 5.9 3.4 7.4 · ·
Quick Ratio 3-point trend, -84.7% 1.1 1.4 7.1 · ·
Efficiency 2
Annual Efficiency data for ZYME
Metric Trend 20252024202320222021
Asset Turnover 3-point trend, +111.8% 0.3 0.1 0.1 · ·
Receivables Turnover 3-point trend, +21.9% 3.5 2.0 2.9 · ·
Per Share 5
Annual Per Share data for ZYME
Metric Trend 20252024202320222021
Book Value / Share 3-point trend, -45.7% $3.60 $4.91 $6.63 · ·
Revenue / Share 3-point trend, +27.3% $1.41 $1.01 $1.10 · ·
Cash Flow / Share 3-point trend, +74.5% $-0.44 $-1.45 $-1.72 · ·
Cash / Share 3-point trend, -75.5% $0.55 $0.96 $2.25 · ·
EPS (TTM) 4-point trend, -156.8% $-1.08 $-1.62 $-1.72 $1.90 ·
Growth Rates 3
Annual Growth Rates data for ZYME
Metric Trend 20252024202320222021
Revenue YoY 5-point trend, +223.4% 38.9% 0.38% -81.6% 1446.0% -31.5%
Revenue CAGR 3Y 3-point trend, -246.0% -36.4% 41.9% 25.0% · ·
Revenue CAGR 5Y 22.2% · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for ZYME
Metric Trend 20252024202320222021
Revenue TTM 4-point trend, -74.3% $106M $76M $76M $412M ·
Net Income TTM 4-point trend, -165.2% $-81M $-123M $-119M $124M ·
Market Cap 3-point trend, +169.8% $1.97B $1.01B $729M · ·
P/E 4-point trend, -689.3% -24.4 -9.0 -6.0 4.1 ·
P/S 3-point trend, +93.5% 18.5 13.2 9.6 · ·
P/B 3-point trend, +367.0% 7.3 3.0 1.6 · ·
P / Tangible Book 4-point trend, +633.8% 7.7 3.1 1.6 1.0 ·
P / Cash Flow 3-point trend, -866.9% -59.5 -9.2 -6.2 · ·
P / FCF 3-point trend, -843.7% -56.9 -9.0 -6.0 · ·
Earnings Yield 4-point trend, -117.0% -4.1% -11.1% -16.6% 24.2% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $106M$76M$76M$412M$27M
Operating Margin % -87.3%-179.7%-181.6%
Net Income $-81M$-123M$-119M$124M$-212M
Diluted EPS $-1.08$-1.62$-1.72$1.90$-4.61
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 5.93.47.4
Quick Ratio 1.11.47.1
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-35M$-112M$-121M

My Metrics Your personal watchlist — selected rows from Full Fundamentals

📊

Pick the metrics that matter to you — click the ➕ next to any row in Full Fundamentals above.

Your selection is saved and follows you across all tickers.