BBOT — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Cormorant Asset Management, LP | $136,234,886 | 17,878,594 | 29.83% | Shares |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $37,227,099 | 4,885,446 | 8.15% | Shares |
| Omega Fund Management, LLC | $25,067,217 | 3,289,661 | 5.49% | Shares |
| Alphabet Inc. | $21,512,220 | 2,823,126 | 4.71% | Shares |
| EcoR1 Capital, LLC | $21,512,220 | 2,823,126 | 4.71% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $21,254,481 | 2,789,302 | 4.65% | Shares |
| ENAVATE SCIENCES GP, LLC | $20,017,329 | 2,626,946 | 4.38% | Shares |
| CITADEL ADVISORS LLC | $19,947,841 | 2,617,827 | 4.37% | Shares |
| NOVO HOLDINGS A/S | $17,145,000 | 2,250,000 | 3.75% | Shares |
| BlackRock, Inc. | $16,413,785 | 2,154,040 | 3.59% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $15,283,045 | 2,005,649 | 3.35% | Shares |
| Laurion Capital Management LP | $15,260,582 | 2,002,701 | 3.34% | Shares |
| ARMISTICE CAPITAL, LLC | $13,441,680 | 1,764,000 | 2.94% | Shares |
| VANGUARD GROUP INC | $9,904,510 | 791,095 | 2.17% | Shares |
| STATE STREET CORP | $7,898,656 | 1,036,569 | 1.73% | Shares |
| Aisling Capital Management LP | $7,757,297 | 1,018,018 | 1.70% | Shares |
| Opaleye Management Inc. | $5,334,000 | 700,000 | 1.17% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $4,744,649 | 622,351 | 1.04% | Shares |
| Granahan Investment Management, LLC | $4,255,968 | 558,526 | 0.93% | Shares |
| SPHERA FUNDS MANAGEMENT LTD. | $3,512,706 | 460,985 | 0.77% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3,048,000 | 400,000 | 0.67% | Shares |
| ROYCE & ASSOCIATES LP | $2,933,250 | 384,941 | 0.64% | Shares |
| Catalio Capital Management, LP | $2,426,261 | 318,407 | 0.53% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $2,221,398 | 291,522 | 0.49% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2,183,267 | 286,518 | 0.48% | Shares |
| Casdin Capital, LLC | $2,151,217 | 282,312 | 0.47% | Shares |
| Ensign Peak Advisors, Inc | $2,084,299 | 273,530 | 0.46% | Shares |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $1,872,418 | 244,441 | 0.41% | Shares |
| FMR LLC | $1,833,272 | 240,587 | 0.40% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $1,456,578 | 191,152 | 0.32% | Shares |
| NORTHERN TRUST CORP | $1,420,993 | 186,482 | 0.31% | Shares |
| Sio Capital Management, LLC | $995,385 | 130,628 | 0.22% | Shares |
| UBS Group AG | $873,671 | 114,655 | 0.19% | Shares |
| MILLENNIUM MANAGEMENT LLC | $803,758 | 105,480 | 0.18% | Shares |
| GOLDMAN SACHS GROUP INC | $777,888 | 102,085 | 0.17% | Shares |
| MOORE CAPITAL MANAGEMENT, LP | $762,000 | 100,000 | 0.17% | Shares |
| Brevan Howard Capital Management LP | $690,714 | 88,895 | 0.15% | Shares |
| Palumbo Wealth Management LLC | $652,455 | 85,624 | 0.14% | Shares |
| BANK OF AMERICA CORP /DE/ | $587,807 | 77,140 | 0.13% | Shares |
| Jump Financial, LLC | $472,440 | 62,000 | 0.10% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $446,532 | 58,600 | 0.10% | Shares |
| Avidity Partners Management LP | $334,160 | 43,853 | 0.07% | Shares |
| TD Asset Management Inc | $325,603 | 42,730 | 0.07% | Shares |
| Virtus Investment Advisers, LLC | $321,716 | 42,220 | 0.07% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $213,238 | 27,984 | 0.05% | Shares |
| TWO SIGMA INVESTMENTS, LP | $201,816 | 26,485 | 0.04% | Shares |
| Rafferty Asset Management, LLC | $172,258 | 22,606 | 0.04% | Shares |
| CITIGROUP INC | $151,425 | 19,872 | 0.03% | Shares |
| Squarepoint Ops LLC | $149,824 | 19,662 | 0.03% | Shares |
| Vanguard Global Advisers, LLC | $138,402 | 18,163 | 0.03% | Shares |
| Schonfeld Strategic Advisors LLC | $87,659 | 11,504 | 0.02% | Shares |
| PROFUND ADVISORS LLC | $83,828 | 11,001 | 0.02% | Shares |
| AXQ CAPITAL, LP | $81,747 | 10,728 | 0.02% | Shares |
| MORGAN STANLEY | $25,755 | 3,380 | 0.01% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $20,115 | 2,626 | 0.00% | Shares |
| BARCLAYS PLC | $15,995 | 2,099 | 0.00% | Shares |
| Tower Research Capital LLC (TRC) | $12,924 | 1,696 | 0.00% | Shares |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | $10,287 | 1,350 | 0.00% | Shares |
| Rockefeller Capital Management L.P. | $7,620 | 1,000 | 0.00% | Shares |
| WELLS FARGO & COMPANY/MN | $2,286 | 300 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $2,286 | 300,000 | 0.00% | Shares |
| Quarry LP | $1,501 | 197 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $282 | 37 | 0.00% | Shares |
| Pacer Advisors, Inc. | $3 | 378 | 0.00% | Shares |