Catalio Capital Management, LP
CIK 1958125 · View on SEC EDGAR ↗
- Portfolio value
- $532.1M
- Positions
- 39
- As of
- June 30, 2026
#3,622 of 9,443 by 13F value · top 38.4%
Portfolio value QoQ: +11.2% 13F does not disclose cash
- Top 10 holdings weight
- 56.72%
- Top 25 holdings weight
- 91.43%
- Positions above 1%
- 29
- Effective number of positions
- 22.3
Based on 13F long-equity holdings only (cash, bonds, shorts not disclosed)
Turnover Q2 2026: 45.9% Est. buys $231,956,199 · sells $257,171,975
Median holding: 2.0 quarters Tracked Q4 2024–Q2 2026 · 41.9% still held
- New positions
- 11
- Increased
- 15
- Decreased
- 8
- Closed
- 13
On this page
- Performance vs S&P How this manager's 13F portfolio performed against the S&P 500.
- Sector breakdown How the portfolio splits across market sectors.
- Portfolio Every stock this institution reports holding, from its latest 13F.
- High-conviction bets The holdings this manager is most concentrated in.
- Biggest new bets Brand-new positions opened in the latest quarter.
- Top moves The biggest position increases and decreases this quarter.
- Exited positions Positions the manager fully sold out of last quarter.
Performance vs S&P 500
Annualized: +34.1% · S&P 500: +18.0%
Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.
Priceable coverage: 95.0% · Options excluded: 0.3%
Sector breakdown
Healthcare
73.9%
Other/Unmapped
26.1%
Full portfolio 39 positions
| Type | Streak | 8Q trend | |||||
|---|---|---|---|---|---|---|---|
| Unknown issuer (CUSIP: 05348Y105) | $55,168,324 | 10.37% | 1,675,830 | Up ×1 | |||
| JNJ Johnson & Johnson Common Stock | $35,288,116 | 6.63% | 138,946 | ||||
| GILD Gilead Sciences, Inc. - Common Stock | $34,024,499 | 6.39% | 269,309 | $11,181,059 | Up ×1 | ||
| BBIO BridgeBio Pharma, Inc. - Common Stock | $33,891,454 | 6.37% | 455,041 | $1,810,094 | Up ×1 | ||
| SNDX Syndax Pharmaceuticals, Inc. - Common Stock | $26,575,158 | 4.99% | 1,215,698 | $2,195,027 | Up ×1 | ||
| DFTX Definium Therapeutics, Inc. - Common Shares | $26,468,091 | 4.97% | 562,672 | $6,850,193 | Down ×1 | ||
| BMY Bristol-Myers Squibb Company Common Stock | $23,794,813 | 4.47% | 412,961 | $-1,722,280 | Down ×2 | ||
| Unknown issuer (CUSIP: 698955101) | $22,554,057 | 4.24% | 824,043 | Up ×1 | |||
| NTRA Natera, Inc. - Common Stock | $22,308,032 | 4.19% | 82,181 | $8,127,341 | Up ×2 | ||
| INCY Incyte Corporation - Common Stock | $21,722,837 | 4.08% | 191,627 | $4,583,491 | Up ×1 | ||
| SEPN Septerna, Inc. - Common Stock | $17,955,730 | 3.37% | 536,152 | $10,882,259 | Up ×1 | ||
| MLYS Mineralys Therapeutics, Inc. - Common Stock | $17,502,520 | 3.29% | 648,722 | $5,608,899 | Up ×2 | ||
| HTFL Heartflow, Inc. - Common Stock | $17,106,834 | 3.21% | 583,055 | $7,287,538 | Up ×2 | ||
| CRVS Corvus Pharmaceuticals, Inc. - Common Stock | $16,148,467 | 3.03% | 1,080,888 | $3,099,487 | Up ×1 | ||
| GPCR Structure Therapeutics Inc. - American Depositary Shares | $14,842,438 | 2.79% | 276,550 | $2,533,170 | Up ×2 | ||
| PTGX Protagonist Therapeutics, Inc. - Common Stock | $13,091,421 | 2.46% | 106,799 | Up ×1 | |||
| IRON Disc Medicine, Inc. - Common Stock | $11,657,346 | 2.19% | 159,384 | $3,794,133 | Up ×2 | ||
| EW Edwards Lifesciences Corporation Common Stock | $11,287,418 | 2.12% | 124,778 | $-292,711 | Down ×2 | ||
| AXSM Axsome Therapeutics, Inc. - Common Stock | $10,569,658 | 1.99% | 43,182 | Up ×1 | |||
| RARE Ultragenyx Pharmaceutical Inc. - Common Stock | $10,559,654 | 1.98% | 316,252 | $-7,264,543 | Down ×1 | ||
| Unknown issuer (CUSIP: 482931102) | $10,326,563 | 1.94% | 468,750 | Up ×1 | |||
| KPTI Karyopharm Therapeutics Inc. - Common Stock | $9,192,153 | 1.73% | 940,855 | $4,191,914 | Up ×2 | ||
| Unknown issuer (CUSIP: 67613T104) | $8,566,168 | 1.61% | 457,839 | Up ×1 | |||
| Unknown issuer (CUSIP: K08588103) | $8,470,760 | 1.59% | 31,759 | Up ×1 | |||
| Unknown issuer (CUSIP: 485925101) | $7,453,125 | 1.40% | 312,500 | Up ×1 | |||
| ELDN Eledon Pharmaceuticals, Inc. - Common Stock | $6,678,580 | 1.26% | 1,695,071 | $1,627,947 | Up ×3 | ||
| FDMT 4D Molecular Therapeutics, Inc. - Common Stock | $6,267,678 | 1.18% | 471,254 | Up ×1 | |||
| MANE Veradermics, Incorporated Common Stock | $5,637,537 | 1.06% | 45,856 | $-5,324,166 | Down ×1 | ||
| DYN Dyne Therapeutics, Inc. - Common Stock | $5,439,873 | 1.02% | 244,929 | $309,917 | Down ×2 | ||
| GUTS Fractyl Health, Inc. - Common Stock | $4,900,454 | 0.92% | 6,168,749 | $2,386,278 | Up ×1 | ||
| IMCR Immunocore Holdings plc - American Depositary Shares | $4,700,429 | 0.88% | 148,045 | $2,157,216 | Up ×1 | ||
| DNTH Dianthus Therapeutics, Inc. - Common Stock | $3,211,089 | 0.60% | 32,941 | $-43,809,958 | Down ×5 | ||
| BBOT BridgeBio Oncology Therapeutics, Inc. - Common Stock | $2,426,261 | 0.46% | 318,407 | ||||
| TARA Protara Therapeutics, Inc. - Common Stock | $1,986,965 | 0.37% | 520,148 | $-1,034,960 | Down ×4 | ||
| HYPR Hyperfine, Inc. - Class A Common Stock | $1,782,055 | 0.33% | 1,320,041 | $356,411 | |||
| ATAI AtaiBeckley Inc. - Common Stock | $1,037,442 | 0.19% | 196,858 | $340,565 | |||
| MGX Metagenomi Therapeutics, Inc. - Common Stock | $629,502 | 0.12% | 528,993 | $-79,349 | |||
| OM Outset Medical, Inc. - Common Stock | $510,965 | 0.10% | 118,279 | $56,774 | |||
| SNSE Sensei Biotherapeutics, Inc. - Common Stock | $367,950 | 0.07% | 14,718 | $-95,961 | |||
| No matches | |||||||
Conviction holdings
Positions increased for 3+ consecutive quarters.
Share counts are as reported in 13F filings (not split-adjusted)
| Security | Value | % of portfolio | Streak |
|---|---|---|---|
| ELDN | $6,678,580 | 1.26% | up ×3 |
Biggest new bets
New positions opened this quarter, largest first.
| Security | Value | Shares | % of portfolio |
|---|---|---|---|
| Unknown issuer (CUSIP: 05348Y105) | $55,168,324 | 1,675,830 | 10.37% |
| JNJ | $35,288,116 | 138,946 | 6.63% |
| Unknown issuer (CUSIP: 698955101) | $22,554,057 | 824,043 | 4.24% |
| PTGX | $13,091,421 | 106,799 | 2.46% |
| AXSM | $10,569,658 | 43,182 | 1.99% |
| Unknown issuer (CUSIP: 482931102) | $10,326,563 | 468,750 | 1.94% |
| Unknown issuer (CUSIP: 67613T104) | $8,566,168 | 457,839 | 1.61% |
| Unknown issuer (CUSIP: K08588103) | $8,470,760 | 31,759 | 1.59% |
| Unknown issuer (CUSIP: 485925101) | $7,453,125 | 312,500 | 1.40% |
| FDMT | $6,267,678 | 471,254 | 1.18% |
| BBOT | $2,426,261 | 318,407 | 0.46% |
Top movers (QoQ)
| Security | Action | Shares Δ | Value Δ |
|---|---|---|---|
| GILD | Bought more | +105K | +$11.2M |
| SEPN | Bought more | +242K | +$10.9M |
| NTRA | Bought more | +11K | +$8.1M |
| HTFL | Bought more | +179K | +$7.3M |
| RARE | Trimmed | -535K | -$7.3M |
| DFTX | Trimmed | -475K | +$6.9M |
| MLYS | Bought more | +210K | +$5.6M |
| MANE | Trimmed | -128K | -$5.3M |
| INCY | Bought more | +10K | +$4.6M |
| KPTI | Bought more | +43K | +$4.2M |
1 position hidden (data completeness check)
Exited positions
Includes corporate events (mergers, delistings) — not all exits are sells
Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.
| Security | Quarter | Shares before | Value before | Price since exit |
|---|---|---|---|---|
| BDX | June 30, 2025 | 203,965 | $46,720,223 | 39.4% |
| ABBV | Dec. 31, 2025 | 154,834 | $35,850,264 | 15.5% |
| SWTX | June 30, 2025 | 758,533 | $33,474,061 | No longer tracked |
| BBIO | Dec. 31, 2025 | 622,729 | $32,344,544 | 8.0% |
| BBOT | March 31, 2026 | 410,700 | $31,414,443 | 3.9% |
| EW | Sept. 30, 2025 | 390,932 | $30,574,792 | 14.9% |
| ASND | June 30, 2026 | 129,111 | $29,531,559 | -3.3% |
| BMY | March 31, 2025 | 499,151 | $28,231,981 | 8.3% |
| LLY | March 31, 2026 | 25,923 | $27,858,930 | 35.9% |
| GILD | Sept. 30, 2025 | 226,875 | $25,153,631 | 30.5% |
| JNJ | March 31, 2026 | 120,840 | $25,007,838 | 9.3% |
| BPMC | March 31, 2025 | 284,654 | $24,827,522 | No longer tracked |
| REGN | March 31, 2026 | 29,797 | $22,999,410 | 8.4% |
| VCYT | June 30, 2025 | 762,225 | $22,599,971 | 53.2% |
| TERN | June 30, 2026 | 409,031 | $21,564,114 | No longer tracked |
| NVST | March 31, 2025 | 1,019,529 | $19,666,714 | 56.3% |
| TEVA | Sept. 30, 2025 | 1,170,372 | $19,615,435 | 84.0% |
| SLNO | June 30, 2026 | 577,808 | $19,345,012 | No longer tracked |
| BSX | June 30, 2026 | 299,318 | $18,782,205 | 15.8% |
| CORT | Sept. 30, 2025 | 239,125 | $17,551,775 | 47.6% |
| EXAS | March 31, 2025 | 309,103 | $17,368,498 | No longer tracked |
| ISRG | March 31, 2026 | 27,209 | $15,410,089 | -19.0% |
| LIVN | June 30, 2025 | 381,648 | $14,991,133 | 73.8% |
| MASI | March 31, 2025 | 87,377 | $14,443,418 | No longer tracked |
| CYTK | June 30, 2026 | 215,501 | $14,203,671 | -9.1% |
| INSP | June 30, 2025 | 85,877 | $13,678,489 | -53.2% |
| EXAS | Dec. 31, 2025 | 248,987 | $13,622,079 | No longer tracked |
| RNA | Dec. 31, 2025 | 263,256 | $11,470,064 | -81.8% |
| IRON | March 31, 2025 | 179,815 | $11,400,271 | 57.7% |
| ADMA | March 31, 2026 | 564,461 | $10,295,769 | 8.9% |
| ACLX | March 31, 2026 | 156,109 | $10,178,307 | No longer tracked |
| ADPT | June 30, 2026 | 722,784 | $10,032,242 | 16.9% |
| HALO | Sept. 30, 2025 | 191,529 | $9,963,339 | 46.1% |
| ADMA | March 31, 2025 | 512,724 | $8,793,217 | -50.6% |
| OCUL | March 31, 2026 | 714,501 | $8,674,042 | 33.1% |
| KALV | June 30, 2026 | 426,551 | $8,586,472 | No longer tracked |
| QURE | June 30, 2026 | 491,116 | $8,029,747 | 7.3% |
| REGN | June 30, 2025 | 12,261 | $7,776,294 | 59.6% |
| NARI | March 31, 2025 | 132,545 | $6,766,422 | No longer tracked |
| OLMA | March 31, 2026 | 267,058 | $6,676,450 | -25.0% |
| BSX | March 31, 2025 | 72,925 | $6,513,661 | -51.0% |
| WGS | Sept. 30, 2025 | 61,507 | $5,677,711 | -24.5% |
| ABVX | June 30, 2026 | 47,193 | $5,254,941 | -10.4% |
| CDTX | Dec. 31, 2025 | 53,333 | $5,107,168 | No longer tracked |
| KROS | June 30, 2025 | 389,384 | $3,967,823 | -18.1% |
| KYTX | Dec. 31, 2025 | 586,909 | $3,521,454 | -11.8% |
| SUPN | June 30, 2026 | 62,019 | $3,205,762 | 2.0% |
| REPL | Sept. 30, 2025 | 330,337 | $3,068,831 | 249.0% |
| PHAT | June 30, 2026 | 247,767 | $2,752,691 | -19.7% |
| NAMS | June 30, 2026 | 83,554 | $2,674,564 | -17.4% |
| GRAL | March 31, 2026 | 30,313 | $2,594,490 | 49.1% |
| TYRA | June 30, 2026 | 67,285 | $2,577,016 | -17.4% |
| FULC | March 31, 2026 | 201,301 | $2,276,714 | -49.4% |
| BLLN | March 31, 2026 | 25,505 | $2,087,329 | 20.5% |
| ZBIO | Sept. 30, 2025 | 215,314 | $2,086,393 | 43.7% |
| VIR | Sept. 30, 2025 | 388,303 | $1,957,047 | 64.8% |
| KPTIXXXX | March 31, 2025 | 2,334,375 | $1,578,738 | No longer tracked |
| FULC | Sept. 30, 2025 | 188,304 | $1,295,532 | -57.8% |
| PVLA | March 31, 2026 | 10,452 | $1,094,011 | 16.2% |
| MLTX | Dec. 31, 2025 | 133,131 | $954,549 | 20.3% |
| BCAX | Sept. 30, 2025 | 97,800 | $908,562 | 55.2% |
| MRSN | Sept. 30, 2025 | 1,567,413 | $463,954 | No longer tracked |