Earnings History
EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-0.20%
Period
EPS Actual
EPS Est
Surprise
March 31, 2026
$-0.53
$-0.54
0.01%
Dec. 31, 2025
$-0.49
$-0.53
0.04%
Sept. 30, 2025
$-1.03
$-0.40
-0.63%
Peer comparison (GICS sub-industry)
Key metrics vs sector peers
Ticker
Market Cap
P/E
Rev YoY
Net Margin
ROE
Gross Margin
BBOT
$1.00B
-2.9
—
—
-146.2%
—
ACHV
—
-4.0
—
—
—
—
CTMX
$725M
—
-44.8%
-22.8%
-15.9%
—
NGNE
$319M
-4.9
—
—
-33.6%
—
STTK
$231M
-5.2
-82.5%
-4880.9%
-70.0%
—
RGNX
$733M
-3.8
104.5%
-113.8%
-122.5%
—
IRWD
$550M
22.5
-15.7%
8.1%
-8.5%
—
GYRE
$645M
353.0
10.2%
8.5%
11.7%
—
ALLO
$314M
-1.6
-76.8%
—
-59.9%
—
Full Fundamentals
All metrics by year — income statement, balance sheet, cash flow
Income Statement13
Annual Income Statement data for BBOT
Metric
Trend
2025
2024
2023
R&D Expense
$121M
$73M
·
SG&A Expense
$25M
$8M
$41.7K
Operating Expenses
$146M
$81M
·
Operating Income
$-146M
$-81M
$-41.7K
Interest Income
$11M
$6M
·
Other Non-op
$-35.0K
$0
·
Income Tax
$0
$0
·
Net Income
$-134M
$-74M
$-41.7K
EPS (Basic)
$-4.30
$-5756.41
·
EPS (Diluted)
$-4.30
$-5756.41
·
Shares (Basic)
31,144,775
12,903
·
Shares (Diluted)
31,144,775
12,903
·
EBITDA
$-146M
$-584.4K
·
Balance Sheet21
Annual Balance Sheet data for BBOT
Metric
Trend
2025
2024
2023
Cash & Equivalents
$374M
$31M
$0
Short-term Investments
$52M
$125M
·
Prepaid Expense
$7M
$3M
·
Current Assets
$432M
$159M
·
PP&E (Net)
$956.0K
$490.0K
·
Other Non-current Assets
$13M
$5M
·
Total Assets
$448M
$164M
$332.9K
Accounts Payable
$1M
$3M
·
Accrued Liabilities
·
$119.7K
$15.0K
Short-term Debt
$534.0K
$483.0K
$70.1K
Current Liabilities
$35M
$20M
$396.5K
Capital Leases
$2M
$0
·
Total Liabilities
$37M
$20M
$396.5K
Total Debt
$534.0K
·
·
Common Stock
$8.0K
$0
·
Paid-in Capital
$768M
$44M
$24.5K
Retained Earnings
$-357M
$-223M
$-88.6K
AOCI
$16.0K
$348.0K
·
Stockholders' Equity
$411M
$-179M
$-116M
Liabilities + Equity
$448M
$164M
$332.9K
Shares Outstanding
79,991,768
28,415
·
Cash Flow9
Annual Cash Flow data for BBOT
Metric
Trend
2025
2024
2023
Stock-based Comp
$6M
$4M
·
Deferred Tax
$0
$0
·
Operating Cash Flow
$-114M
$-55M
·
CapEx
$606.0K
$49.0K
·
Investing Cash Flow
$73M
$-121M
·
Stock Issued
$112M
·
·
Net Stock Activity
$112M
·
·
Financing Cash Flow
$383M
$206M
·
Free Cash Flow
$-114M
·
·
Profitability2
Annual Profitability data for BBOT
Metric
Trend
2025
2024
2023
ROA
-43.8%
7.8%
·
ROE
-146.2%
-9.3%
·
Liquidity & Solvency3
Annual Liquidity & Solvency data for BBOT
Metric
Trend
2025
2024
2023
Current Ratio
12.3
10.4
·
Quick Ratio
12.1
9.1
·
Debt / Equity
0.0
·
·
Per Share4
Annual Per Share data for BBOT
Metric
Trend
2025
2024
2023
Book Value / Share
$5.14
·
·
Cash Flow / Share
$-3.66
·
·
Cash / Share
$4.67
·
·
EPS (TTM)
$-4.30
$-5756.41
·
Valuation (TTM)11
Annual Valuation (TTM) data for BBOT
Metric
Trend
2025
2024
2023
Net Income TTM
$-134M
$-74M
·
Market Cap
$1.00B
·
·
Enterprise Value
$577M
·
·
P/E
-2.9
-0.0
·
P/B
2.4
·
·
P / Tangible Book
2.4
·
·
P / Cash Flow
-8.8
·
·
P / FCF
-8.7
·
·
EV / EBITDA
-4.0
·
·
EV / FCF
-5.0
·
·
Earnings Yield
-34.4%
-54823.0%
·
Income Statement13
Quarterly Income Statement data for BBOT
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
R&D Expense
$49M
$40M
$38M
$35M
$27M
$21M
$20M
$18M
·
·
SG&A Expense
$11M
$6M
$7M
$14M
$3M
$3M
$6M
$2M
$152.3K
$66.7K
Operating Expenses
$60M
$46M
$43M
$49M
$30M
$23M
$22M
$20M
·
·
Operating Income
$-60M
$-46M
$-93M
$-49M
$-30M
$-23M
$-61M
$-20M
$-152.3K
$-66.7K
Interest Income
$4M
$4M
$4M
$3M
$2M
$2M
$255.2K
$2M
$2M
$1M
Other Non-op
$-14.0K
$-94.0K
$-4M
$-30.0K
$-8.0K
$-2.0K
$-4M
$0
$2M
$1M
Income Tax
$0
·
$0
$0
$0
$0
$0
$0
·
·
Net Income
$-56M
$-42M
$-39M
$-45M
$-28M
$-22M
$-20M
$-17M
$-22M
$-15M
EPS (Basic)
$-705.20
$-526.11
$2.19
$-1.03
$-566.46
$-54.23
$-833.69
$-1562.18
·
·
EPS (Diluted)
$-705.20
$-526.11
$2.19
$-1.03
$-566.46
$-54.23
$-833.69
$-1562.18
·
·
Shares (Basic)
80,054,000
80,032
16,459,785
43,491,085
50,198,000
406,723
1,814
11,089
·
·
Shares (Diluted)
80,054,000
80,032
16,459,785
43,491,085
50,198,000
406,723
1,814
11,089
·
·
EBITDA
$-60M
$-46M
·
$-49M
$-1M
$-2M
·
$-146.9K
$-152.3K
$-66.7K
Balance Sheet21
Quarterly Balance Sheet data for BBOT
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Cash & Equivalents
$54M
$53M
$374M
$409M
$664.2K
$963.1K
$31M
$2M
$2M
$2M
Short-term Investments
$172M
$200M
$52M
$60M
·
·
$125M
·
·
·
Prepaid Expense
$16M
$14M
$7M
$7M
$62.5K
·
$3M
·
$11.3K
$16.3K
Current Assets
$242M
$267M
$432M
$476M
$876.8K
$1M
$159M
$2M
$2M
$2M
PP&E (Net)
$878.0K
$938.0K
$956.0K
$827.0K
·
·
$490.0K
·
·
·
Other Non-current Assets
$13M
$11M
$13M
$5M
·
·
$5M
·
·
·
Total Assets
$377M
$418M
$448M
$485M
$197M
$196M
$164M
$192M
$190M
$188M
Accounts Payable
$7M
$12M
$1M
$4M
$3M
·
$3M
·
·
·
Accrued Liabilities
·
·
·
·
·
$2M
·
$126.7K
$79.1K
$23.3K
Short-term Debt
·
$716.0K
$534.0K
$691.0K
·
·
$483.0K
·
·
·
Current Liabilities
$52M
$43M
$35M
$36M
$3M
$2M
$20M
$126.7K
$79.1K
$23.3K
Capital Leases
$2M
$2M
$2M
$2M
·
·
$0
·
·
·
Total Liabilities
$54M
$45M
$37M
$38M
$8M
$7M
$20M
$6M
$6M
$6M
Total Debt
·
$716.0K
·
$691.0K
·
·
·
·
·
·
Common Stock
$8.0K
$8.0K
$8.0K
$8.0K
·
·
$0
·
·
$51
Paid-in Capital
$779M
$772M
$768M
$764M
·
·
$44M
·
·
·
Retained Earnings
$-455M
$-399M
$-357M
$-318M
$-7M
$-6M
$-223M
$-4M
$-3M
$-3M
AOCI
$-959.0K
$-981.0K
$16.0K
$36.0K
·
·
$348.0K
·
·
·
Stockholders' Equity
$323M
$372M
$411M
$447M
$-7M
$-6M
$-179M
$-4M
$-3M
$-3M
Liabilities + Equity
$377M
$418M
$448M
$485M
$197M
$196M
$164M
$192M
$190M
$188M
Shares Outstanding
80,115,002
80,088,931
79,991,768
79,196,710
·
·
28,415
·
·
·
Cash Flow8
Quarterly Cash Flow data for BBOT
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Stock-based Comp
$7M
$4M
$3M
$3M
$36.0K
$627.0K
$4M
$77.4K
$77.4K
$39.4K
Operating Cash Flow
$-44M
$-36M
$-42M
$-71M
$-298.9K
$-20M
$-15M
$-39M
$-29.1K
$-618.0K
CapEx
$47.0K
$24.0K
$73.0K
$140.0K
$231.0K
$162.0K
$10.0K
·
·
·
Investing Cash Flow
$46M
$-285M
$8M
$41M
$10M
$15M
$26M
$38M
$0
$-184M
Stock Issued
$0
$112M
$-9M
·
·
·
·
·
·
·
Net Stock Activity
·
$112M
·
·
·
·
·
·
·
·
Financing Cash Flow
$37.0K
$295.0K
$-586.0K
$365M
$19M
$-404.0K
$52.0K
$20M
$0
$186M
Free Cash Flow
·
$-36M
·
·
·
·
·
·
·
·
Profitability2
Quarterly Profitability data for BBOT
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
ROA
-19.7%
-13.7%
·
-13.2%
0.47%
-0.25%
·
2.4%
2.3%
1.2%
ROE
-35.8%
-23.0%
·
-20.2%
-17.2%
10.4%
·
-132.7%
-131.2%
-68.3%
Liquidity & Solvency3
Quarterly Liquidity & Solvency data for BBOT
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Current Ratio
4.7
6.2
·
13.3
0.3
0.7
·
16.1
26.2
90.4
Quick Ratio
4.4
5.8
·
13.1
0.3
0.5
·
14.1
22.9
79.0
Debt / Equity
·
0.0
·
0.0
·
·
·
·
·
·
Per Share4
Quarterly Per Share data for BBOT
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Book Value / Share
$4.03
$4.65
·
$5.64
·
·
·
·
·
·
Cash Flow / Share
·
$-448.78
·
·
·
·
·
·
·
·
Cash / Share
$0.67
$0.66
·
$5.16
·
·
·
·
·
·
EPS (TTM)
$-1798.80
·
·
·
·
·
·
·
·
·
Valuation (TTM)11
Quarterly Valuation (TTM) data for BBOT
Metric
Trend
Q2 2026
Q1 2026
Q4 2025
Q3 2025
Q2 2025
Q1 2025
Q4 2024
Q3 2024
Q2 2024
Q1 2024
Net Income TTM
$-172M
$-137M
·
$-113M
$-90M
$-77M
·
·
·
·
Market Cap
$610M
$717M
·
$917M
·
·
·
·
·
·
Enterprise Value
·
$465M
·
$450M
·
·
·
·
·
·
P/E
-0.0
·
·
·
·
·
·
·
·
·
P/B
1.9
1.9
·
2.1
·
·
·
·
·
·
P / Tangible Book
1.9
1.9
·
2.1
·
·
·
·
·
·
P / Cash Flow
·
-20.0
·
·
·
·
·
·
·
·
P / FCF
·
-19.9
·
·
·
·
·
·
·
·
EV / EBITDA
·
-10.1
·
-9.1
·
·
·
·
·
·
EV / FCF
·
-12.9
·
·
·
·
·
·
·
·
Earnings Yield
-23606.3%
·
·
·
·
·
·
·
·
·
Financial Statements
Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
2025-12-31
2024-12-31
2023-12-31
Net Income
$-134M
$-74M
$-41.7K
Diluted EPS
$-4.30
$-5756.41
—
Balance Sheet
2025-12-31
2024-12-31
2023-12-31
Debt / Equity
0.0
—
—
Current Ratio
12.3
10.4
—
Quick Ratio
12.1
9.1
—
Cash Flow
2025-12-31
2024-12-31
2023-12-31
Free Cash Flow
$-114M
—
—
My Metrics
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Institutional owners (13F)
65 filers · $429.4M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
New positions
Exited positions
Increased
Decreased
Net shares change
20
(+3 vs prior Q)
17
(+10 vs prior Q)
16
(-3 vs prior Q)
14
(+3 vs prior Q)
+2.4M
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners
3 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
Filer
Filed
Stake
Status
Purpose
Filing
Bihua Chen, Cormorant Private Healthcare Fund III, LP, Cormorant Private Healthcare GP III, LLC, Cormorant Private Healthcare Fund V, LP, Cormorant Private Healthcare GP V, LLC, Cormorant Global Healthcare Master Fund, LP, Cormorant Global Healthcare GP, LLC, Helix Holdings II LLC
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership
Held by 6 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.