CRL Charles River Laboratories International, Inc. Common Stock

NYSE · Life Sciences Tools & Services · View on SEC EDGAR ↗
$290.01
Price · Aug 19, 2026
Fundamentals as of Aug 5, 2026

About Charles River Laboratories International, Inc. Common Stock Company overview from Wikipedia

Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices. Its operations span at least 20 countries, offering research models, safety assessment, and manufacturing support services to pharmaceutical, biotechnology, and government clients.

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Charles River Laboratories International, Inc. is an American pharmaceutical and biotechnology contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides preclinical and clinical laboratory services for the development of new drugs, vaccines, and medical devices. Its operations span at least 20 countries, offering research models, safety assessment, and manufacturing support services to pharmaceutical, biotechnology, and government clients.

Charles River Laboratories is considered one of the largest CROs globally, known for its role in toxicology studies, animal research models, and microbial testing services used in regulatory submissions to health authorities such as the U.S. Food and Drug Administration (FDA). The company has also been the subject of public scrutiny and regulatory attention over its use of laboratory animals, including dogs, primates, and horseshoe crabs.

As of 2024, the company employs over 20,000 people worldwide and is publicly traded on the New York Stock Exchange under the ticker symbol CRL.

History

Charles River was founded in 1947 by Henry Foster, a young veterinarian who purchased one thousand rat cages from a Virginia farm and set up a one-person laboratory in Boston overlooking the Charles River. He supplied local researchers with laboratory animals.

In 1955, the company's headquarters were relocated to their current home in Wilmington, Massachusetts. The organization became an international entity in 1966 by opening a new animal production facility in France.

The first commercial, comprehensive genetic monitoring program was implemented by Charles River in 1981. Three years later, they were acquired by Bausch & Lomb. In 1988, the organization began creating transgenic mice and rats. In the 1990s, they began in vitro endotoxin testing. In the 1990s, Jim Foster bought Charles River back from Bausch & Lomb, and the company later went public on the New York Stock Exchange.

Charles River launched the Humane Care Imperative in 2002, designed to raise awareness and train employees on animal welfare's importance. The same year, they were named "Company of the Year" by The Boston Globe. The company introduced preconditioning services in 2005 to provide customers with study-ready animals.

In 2008, Charles River signed a ten-year contract to partner with the National Cancer Institute and opened a facility in Frederick, Maryland.

In April 2019, Charles River announced it would cease its San Diego operations, moving the breeding of rodents for testing compounds to Hollister, California.

In March 2023, the Born Free USA animal welfare organization protested against Charles River's plan to export 1,000 endangered juvenile long-tail macaques to Cambodia for testing.

Acquisitions

In 1988, Charles River purchased Specific Pathogen Antigen Free Avian Services (SPAFAS) and serologic diagnostic services Merck, Sharp, and Dohme.

Between 1996 and 2000, the company acquired Endosafe, Inc. and Sierra Biomedical.

In October 2003, Charles River Laboratories merged with Inveresk, a research company based in the United Kingdom. The company was known then as Charles River Laboratories. Inveresk specialised in clinical research and pre-clinical testing, and their main facilities are in Edinburgh, Scotland. In late 2009, Charles River sold its Clinical Services Division in Edinburgh to Quotient Bioresearch.

In 2010, Charles River Laboratories attempted to acquire WuXi PharmaTech, a China-based contract research organization, but the offer was withdrawn when the deal faced opposition from several large Charles River investors, including Relational Investors, JANA Partners, and Neuberger Berman. The proxy advisory firm RiskMetrics had also recommended that Charles River's shareholders vote against the proposed deal.

From 2008 to 2013, Charles River acquires several companies including NewLab Bioquality AG, MIR Preclinical Services, Piedmont Research Center, LLC, Cerebricon, Ltd., Accugenix, and Vital River, allowing the company to expand their research models and services portfolio to drug development and discovery markets in China.

The acquisitions of Argenta and BioFocus in 2014 allowed Charles River to establish itself as a full-service, early-stage contract research organization with integrated in vitro and in vivo capabilities from target discovery through pre-clinical development.

In July 2015, the company announced it would acquire Celsis International for $212 million.

In 2016, the company announced it was set to acquire WIL Research for approximately $585 million in cash and Blue Stream Laboratories.

In August 2017, the business announced it would acquire Brains On-Line.

In January 2018, the company announced it would acquire KWS BioTest for up to £18 million ($24.4 million). In February of the same year, Charles River announced it would acquire MPI Research for approximately $800 million in cash. The transaction was completed on April 3, 2018.

In February 2019, the company announced it would acquire Citoxlab for €448 million in cash (approximately $500 million), including the former acquisitions of the French company, AccelLAB, Atlanbio and Solvo Biotechnology. The transaction was completed on April 29. In December of the same year the business announced it would acquire HemaCare for approximately $380 million in cash.

In August 2020, the company announced it would acquire Cellero for $38 million in cash.

In January 2021, the company announced it would acquire Distributed Bio, Inc., an antibody discovery business.

In February 2021, Charles River announced it would acquire Cognate BioServices, Inc. for $875 million.

In March 2021, Charles River announced the acquisition of Retrogenix for $48 million.

In May 2021, Charles River announced the acquisition of Vigene Biosciences, a gene therapy contract development and manufacturing organization (CDMO), for $292.5 million.

In October 2021, a Japanese subsidiary of Charles River was acquired by Jackson Laboratory for $63M USD.

In April 2022, the company announced it would acquire Explora BioLabs.

In January 2023, the business announced it would acquire SAMDI Tech, Inc.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

CRL Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$290.00
Market Cap
$14.27B
P/E (TTM)
-99.7
EPS (TTM)
$-2.91
Revenue (TTM)
$4.02B
Div Yield
ROE
-4.4%
Debt/Equity
0.0
52W Range
$144 – $291

CRL Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $4.02B
10-point trend, +138.8%
2016-12-31 2025-12-27
EPS $-2.91
10-point trend, -190.1%
2016-12-31 2025-12-27
Free Cash Flow $518M
10-point trend, +111.6%
2016-12-31 2025-12-27
Margins -3.6%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
CRL
Peer Median
P/E (TTM)
5-point trend, -244.1%
-99.7
39.9
P/S (TTM)
5-point trend, -52.6%
3.6
5.6
P/B
5-point trend, -56.9%
4.5
4.1
EV / EBITDA
5-point trend, +6.5%
32.8
Price / FCF
5-point trend, -44.8%
27.5

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
CRL
Peer Median
Operating Margin
5-point trend, -96.2%
0.63%
Net Profit Margin
5-point trend, -132.5%
-3.6%
11.7%
ROA
5-point trend, -131.5%
-2.0%
4.7%
ROE
5-point trend, -125.9%
-4.4%
8.5%
ROIC
5-point trend, -94.1%
1.1%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
CRL
Peer Median
Debt / Equity
5-point trend, +0.00
0.0
15.3
Current Ratio
5-point trend, +4.7%
1.3
1.7
Quick Ratio
5-point trend, -3.9%
0.8

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
CRL
Peer Median
Revenue YoY
5-point trend, +13.4%
-0.85%
Revenue CAGR 3Y
5-point trend, +13.4%
0.33%
Revenue CAGR 5Y
5-point trend, +13.4%
6.6%
EPS YoY
5-point trend, -138.3%
-97.8%
Net Income YoY
5-point trend, -136.9%
-95.3%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
CRL
Peer Median
EPS (Diluted)
5-point trend, -138.3%
$-2.91

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
CRL
Peer Median

CRL Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 22 analysts
  • Strong Buy 5 22.7%
  • Buy 10 45.5%
  • Hold 7 31.8%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

14 analysts · 2026-08-14
Median target $300.00 +3.4%
Mean target $281.00 -3.1%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.21%
Period EPS Actual EPS Est Surprise
June 30, 2026 $3.02 $2.76 0.26%
March 31, 2026 $2.06 $1.96 0.10%
Dec. 31, 2025 $2.39 $2.37 0.02%
Sept. 30, 2025 $2.43 $2.36 0.07%
June 30, 2025 $3.12 $2.52 0.60%
March 31, 2025 $2.34 $2.10 0.24%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CRL $10.02B -70.0 -0.85% -3.6% -4.4%
ILMN $20.65B 24.8 -0.66% 19.6% 34.1% 66.1%
MTD $28.38B 33.2 4.0% 21.6% -615.5% 59.4%
WST $19.81B 40.5 6.2% 16.1% 16.2% 35.9%
MEDP $15.93B 36.8 20.0% 17.8% 142.9%
TEM -41.9 83.4% -19.3% -61.2%
RVTY $10.86B 46.7 3.7% 8.5% 3.3%
TECH $7.97B 111.8 5.2% 6.0% 3.7% 64.8%
TEM -41.9 83.4% -19.3% -61.2%
RGEN $9.23B 190.5 16.4% 6.6% 2.4%
BIO

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +209.4% $4.02B $4.05B $4.13B $3.98B $3.54B $2.92B $2.62B $2.27B $1.86B $1.68B $1.36B $1.30B
Cost of Revenue 4-point trend, +8.7% · · · · · · · · $290M $277M $264M $266M
SG&A Expense 12-point trend, +176.2% $743M $751M $748M $665M $620M $529M $518M $444M $371M $365M $300M $269M
Operating Income 12-point trend, -85.8% $25M $227M $617M $651M $590M $433M $351M $331M $288M $238M $206M $178M
Interest Expense 10-point trend, +1044.0% · · $137M $59M $74M $86M $61M $64M $30M $28M $15M $12M
Interest Income 12-point trend, +328.1% $5M $9M $5M $780.0K $652.0K $834.0K $2M $812.0K $690.0K $1M $1M $1M
Other Non-op 12-point trend, -310.6% $-23M $-17M $96M $31M $-36M $100M $12M $13M $38M $12M $3M $11M
Pretax Income 12-point trend, -156.0% $-100M $93M $581M $623M $481M $447M $304M $282M $297M $223M $195M $178M
Income Tax 12-point trend, -10.5% $43M $68M $101M $130M $82M $82M $50M $54M $171M $67M $43M $48M
Net Income 12-point trend, -213.9% $-144M $22M $475M $486M $391M $364M $252M $226M $123M $155M $149M $127M
EPS (Basic) 12-point trend, -207.0% $-2.91 $0.20 $9.27 $9.57 $7.77 $7.35 $5.17 $4.72 $2.60 $3.29 $3.21 $2.72
EPS (Diluted) 12-point trend, -209.4% $-2.91 $0.20 $9.22 $9.48 $7.60 $7.20 $5.07 $4.62 $2.54 $3.23 $3.13 $2.66
Shares (Basic) 12-point trend, +6.3% 49,564,000 51,380,000 51,227,000 50,812,000 50,293,000 49,550,000 48,730,000 47,947,000 47,481,000 47,014,000 46,496,000 46,627,000
Shares (Diluted) 12-point trend, +4.2% 49,564,000 51,628,000 51,451,000 51,301,000 51,425,000 50,611,000 49,693,000 49,018,000 48,564,000 47,958,000 47,634,000 47,558,000
EBITDA 12-point trend, +56.3% $428M $589M $931M $955M $855M $668M $549M $493M $419M $364M $301M $274M
Balance Sheet 30
Annual Balance Sheet data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +33.6% $214M $195M $277M $234M $241M $228M $238M $195M $164M $118M $118M $160M
Short-term Investments 7-point trend, -94.8% · · · · $1M $1M $941.0K $885.0K $28M $4M $21M ·
Receivables 12-point trend, +174.8% $709M $721M $780M $752M $643M $618M $514M $472M $430M $364M $270M $258M
Inventory 12-point trend, +235.9% $299M $279M $380M $256M $199M $186M $161M $128M $115M $96M $94M $89M
Prepaid Expense 12-point trend, +185.3% $129M $106M $83M $108M $97M $73M $56M $49M $81M $45M $47M $45M
Other Current Assets 7-point trend, -100.0% · · · · · $0 $300.0K $300.0K $0 $45M $47M $73M
Current Assets 12-point trend, +149.8% $1.45B $1.40B $1.61B $1.44B $1.27B $1.20B $1.02B $898M $827M $657M $559M $579M
PP&E (Net) 12-point trend, +144.6% $1.66B $1.60B $1.64B $1.47B $1.29B $1.12B $1.04B $933M $782M $756M $678M $677M
PP&E (Gross) 12-point trend, +139.7% $3.19B $3.06B $2.98B $2.63B $2.39B $2.21B $2.02B $1.81B $1.58B $1.46B $1.32B $1.33B
Accum. Depreciation 12-point trend, +134.8% $1.54B $1.45B $1.34B $1.16B $1.10B $1.09B $978M $874M $801M $706M $645M $655M
Goodwill 12-point trend, +760.9% $2.76B $2.85B $3.10B $2.85B $2.71B $1.81B $1.54B $1.25B $805M $788M $439M $321M
Intangibles 12-point trend, +21.1% $340M $723M $864M $955M $1.06B $788M $689M $611M $370M $394M $281M $281M
Other Non-current Assets 12-point trend, +301.9% $293M $278M $309M $148M $152M $353M $213M $144M $124M $88M $72M $73M
Total Assets 12-point trend, +281.5% $7.14B $7.53B $8.20B $7.60B $7.02B $5.49B $4.69B $3.86B $2.93B $2.71B $2.07B $1.87B
Accounts Payable 12-point trend, +340.0% $149M $140M $169M $206M $198M $122M $111M $66M $78M $68M $37M $34M
Accrued Liabilities 12-point trend, +300.8% $270M $232M $228M $220M $229M $150M $139M $107M $90M $84M $89M $67M
Current Liabilities 12-point trend, +280.2% $1.12B $994M $1.06B $1.09B $1.03B $840M $710M $558M $464M $430M $312M $295M
Capital Leases 7-point trend, +273.4% $434M $484M $419M $390M $253M $156M $116M · · · · ·
Deferred Tax 12-point trend, +312.4% $95M $107M $191M $216M $240M $217M $167M $144M $90M $56M $48M $23M
Other Non-current Liabilities 12-point trend, +38.9% $138M $195M $223M $175M $243M $205M $183M $179M $195M $159M $89M $100M
Total Liabilities 12-point trend, +236.5% $3.92B $4.02B $4.54B $4.58B $4.43B $3.35B $3.03B $2.52B $1.87B $1.86B $1.30B $1.17B
Long-term Debt 5-point trend, +124.7% · · · · · · · $1.61B $1.09B $1.18B $814M $717M
Total Debt 12-point trend, -100.0% $166.0K $155.0K $3M $1M $101.0K $47M $36M $1.65B $1.12B $1.21B $836M $754M
Common Stock 12-point trend, -41.8% $492.0K $511.0K $513.0K $509.0K $505.0K $498.0K $489.0K $482.0K $875.0K $863.0K $855.0K $845.0K
Retained Earnings 12-point trend, +1100.6% $1.39B $1.81B $1.89B $1.43B $981M $625M $280M $42M $289M $165M $11M $-139M
Treasury Stock 12-point trend, -100.0% $0 $0 $0 $0 $0 $0 $0 $55.0K $1.66B $1.55B $1.54B $1.42B
AOCI 12-point trend, -131.4% $-172M $-317M $-196M $-262M $-165M $-139M $-178M $-173M $-145M $-254M $-136M $-74M
Stockholders' Equity 12-point trend, +370.8% $3.16B $3.46B $3.60B $2.98B $2.53B $2.11B $1.63B $1.32B $1.05B $837M $733M $672M
Liabilities + Equity 12-point trend, +281.5% $7.14B $7.53B $8.20B $7.60B $7.02B $5.49B $4.69B $3.86B $2.93B $2.71B $2.07B $1.87B
Shares Outstanding 12-point trend, +4.0% 49,217,000 51,141,000 51,338,000 50,944,000 50,480,000 49,767,000 48,936,000 48,209,000 47,402,000 47,363,000 46,698,000 47,327,000
Cash Flow 18
Annual Cash Flow data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, +318.2% $403M $362M $314M $304M $266M $235M $198M $162M $131M $127M $95M $96M
Stock-based Comp 12-point trend, +129.0% $71M $70M $72M $74M $71M $56M $57M $47M $44M $44M $40M $31M
Deferred Tax 12-point trend, -953.7% $-75M $-67M $-51M $-33M $-20M $2M $-21M $-10M $28M $3M $4M $9M
Amort. of Intangibles 12-point trend, +589.9% $179M $138M $137M $147M $125M $112M $90M $65M $41M $42M $24M $26M
Restructuring 12-point trend, +1181.0% $100M $107M $30M $8M $7M $13M $14M $10M $5M $18M $8M $8M
Other Non-cash 11-point trend, +122367.8% $483M $348M $-126M $-211M $53M $-111M $-5M $16M $-8M $-28M $-395.0K ·
Operating Cash Flow 12-point trend, +192.6% $738M $735M $684M $620M $761M $547M $481M $441M $318M $317M $307M $252M
CapEx 12-point trend, +285.0% $219M $233M $319M $325M $229M $167M $141M $140M $82M $55M $63M $57M
Investing Cash Flow 10-point trend, +69.8% $-209M $-245M $-563M $-608M $-1.44B $-602M $-682M $-955M $-73M $-693M · ·
Debt Issued 10-point trend, +17.5% $1.23B $1.08B $776M $2.95B $6.95B $2.23B $3.36B $2.76B $237M $1.04B · ·
Net Debt Issued 8-point trend, -55.4% $1.23B $1.08B $776M $2.95B $6.95B $2.23B $3.36B $2.76B · · · ·
Stock Repurchased 12-point trend, +195.6% $361M $119M $24M $39M $41M $24M $18M $14M $107M $12M $117M $122M
Net Stock Activity 12-point trend, -195.6% $-361M $-119M $-24M $-39M $-41M $-24M $-18M $-14M $-107M $-12M $-117M $-122M
Financing Cash Flow 10-point trend, -241.0% $-537M $-551M $-86M $-42M $673M $47M $232M $558M $-208M $381M · ·
Net Change in Cash 12-point trend, +154.6% $10M $-79M $43M $-5M $13M $-7M $43M $31M $46M $-69.0K $-43M $4M
Taxes Paid 8-point trend, +77.0% $120M $126M $90M $76M $75M $60M $54M $68M · · · ·
Free Cash Flow 12-point trend, +165.6% $518M $502M $365M $295M $532M $380M $340M $301M $236M $245M $225M $195M
Levered FCF 10-point trend, +35.4% · · $252M $248M $471M $309M $290M $250M $223M $226M $213M $186M
Profitability 7
Annual Profitability data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 12-point trend, -95.4% 0.63% 5.6% 14.9% 16.4% 16.7% 14.8% 13.4% 14.6% 15.5% 14.1% 15.1% 13.7%
Net Margin 11-point trend, -132.8% -3.6% 0.55% 11.5% 12.2% 11.0% 12.5% 9.6% 10.0% 6.6% 9.2% 10.9% ·
Pretax Margin 12-point trend, -118.1% -2.5% 2.3% 14.1% 15.7% 13.6% 15.3% 11.6% 12.4% 16.0% 13.3% 14.3% 13.7%
EBITDA Margin 12-point trend, -49.5% 10.7% 14.5% 22.6% 24.0% 24.2% 22.8% 20.9% 21.8% 22.5% 21.6% 22.1% 21.1%
ROA 11-point trend, -126.0% -2.0% 0.28% 6.0% 6.7% 6.2% 7.1% 5.9% 6.7% 4.4% 6.5% 7.6% ·
ROE 11-point trend, -120.5% -4.4% 0.63% 14.4% 17.6% 16.8% 19.4% 17.1% 19.2% 13.1% 19.7% 21.2% ·
ROIC 12-point trend, -87.5% 1.1% 1.8% 14.2% 17.3% 19.3% 16.4% 17.6% 9.0% 5.6% 8.1% 10.2% 9.1%
Liquidity & Solvency 5
Annual Liquidity & Solvency data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, -37.0% 1.3 1.4 1.5 1.3 1.2 1.4 1.4 1.6 1.8 1.5 1.8 2.0
Quick Ratio 12-point trend, -41.7% 0.8 0.9 1.0 0.9 0.9 1.0 1.1 1.2 1.3 1.1 1.2 1.4
Debt / Equity 12-point trend, -100.0% 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 1.4 1.1 1.1
LT Debt / Equity 5-point trend, +15.0% · · · · · · · 1.2 1.0 1.4 1.1 1.1
Interest Coverage 10-point trend, -69.6% · · 4.5 11.0 8.0 5.0 5.8 5.2 9.7 8.6 13.7 14.9
Efficiency 3
Annual Efficiency data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 12-point trend, -25.8% 0.5 0.5 0.5 0.5 0.6 0.6 0.6 0.7 0.7 0.7 0.7 0.7
Inventory Turnover 4-point trend, -8.0% · · · · · · · · 2.7 2.9 2.9 3.0
Receivables Turnover 12-point trend, +3.6% 5.6 5.4 5.4 5.7 5.6 5.2 5.3 5.0 4.7 5.3 5.2 5.4
Per Share 5
Annual Per Share data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, +352.7% $64.30 $67.69 $70.06 $58.42 $50.21 $42.49 $33.40 $27.33 $22.05 $17.67 $15.70 $14.20
Revenue / Share 10-point trend, +131.1% $81.01 $78.45 $80.26 $77.50 $68.84 $57.77 $52.75 $46.23 $38.25 $35.06 · ·
Cash Flow / Share 10-point trend, +137.6% $14.88 $14.23 $13.29 $12.08 $14.79 $10.80 $9.68 $9.00 $6.55 $6.26 · ·
Cash / Share 12-point trend, +28.5% $4.34 $3.81 $5.39 $4.59 $4.78 $4.59 $4.86 $4.05 $3.46 $2.48 $2.53 $3.38
EPS (TTM) 12-point trend, -209.4% $-2.91 $0.20 $9.22 $9.48 $7.60 $7.20 $5.07 $4.62 $2.54 $3.23 $3.13 $2.66
Growth Rates 7
Annual Growth Rates data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -104.0% -0.85% -1.9% 3.9% 12.3% 21.1% · · · · · · ·
Revenue CAGR 3Y 3-point trend, -97.3% 0.33% 4.6% 12.2% · · · · · · · · ·
Revenue CAGR 5Y 6.6% · · · · · · · · · · ·
EPS YoY 4-point trend, -1859.5% · -97.8% -2.7% 24.7% 5.6% · · · · · · ·
EPS CAGR 3Y 2-point trend, -917.9% · -70.3% 8.6% · · · · · · · · ·
Net Income YoY 4-point trend, -1402.2% · -95.3% -2.4% 24.4% 7.3% · · · · · · ·
Net Income CAGR 3Y 2-point trend, -767.7% · -61.6% 9.2% · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for CRL
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +209.4% $4.02B $4.05B $4.13B $3.98B $3.54B $2.92B $2.62B $2.27B $1.86B $1.68B $1.36B $1.30B
Net Income TTM 12-point trend, -213.9% $-144M $22M $475M $486M $391M $364M $252M $226M $123M $155M $149M $127M
Market Cap 12-point trend, +229.4% $10.02B $9.52B $12.14B $11.10B $18.64B $12.53B $7.43B $5.39B $5.19B $3.61B $3.74B $3.04B
Enterprise Value 12-point trend, +169.8% $9.81B $9.33B $11.86B $10.87B $18.40B $12.34B $7.23B $6.84B $6.12B $4.70B $4.46B $3.64B
P/E 12-point trend, -389.6% -70.0 930.8 25.6 23.0 48.6 35.0 30.0 24.2 43.1 23.6 25.6 24.2
P/S 12-point trend, +6.5% 2.5 2.4 2.9 2.8 5.3 4.3 2.8 2.4 2.8 2.1 2.7 2.3
P/B 12-point trend, -30.0% 3.2 2.8 3.4 3.7 7.4 5.9 4.5 4.1 5.0 4.3 5.1 4.5
P / Tangible Book 166.0 · · · · · · · · · · ·
P / Cash Flow 12-point trend, +12.6% 13.6 13.0 17.7 17.9 24.5 22.9 15.5 12.2 16.3 12.0 13.0 12.1
P / FCF 12-point trend, +24.0% 19.3 19.0 33.2 37.6 35.0 33.0 21.8 17.9 22.0 14.7 16.6 15.6
EV / EBITDA 12-point trend, +72.6% 22.9 15.8 12.7 11.4 21.5 18.5 13.2 13.9 14.6 12.9 14.8 13.3
EV / FCF 12-point trend, +1.6% 18.9 18.6 32.5 36.9 34.6 32.5 21.2 22.7 26.0 19.2 19.8 18.6
EV / Revenue 12-point trend, -12.8% 2.4 2.3 2.9 2.7 5.2 4.2 2.8 3.0 3.3 2.8 3.3 2.8
Earnings Yield 12-point trend, -134.5% -1.4% 0.11% 3.9% 4.3% 2.1% 2.9% 3.3% 4.1% 2.3% 4.2% 3.9% 4.1%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-272024-12-282023-12-302022-12-312021-12-25
Revenue $4.02B$4.05B$4.13B$3.98B$3.54B
Operating Margin % 0.63%5.6%14.9%16.4%16.7%
Net Income $-144M$22M$475M$486M$391M
Diluted EPS $-2.91$0.20$9.22$9.48$7.60
Balance Sheet
2025-12-272024-12-282023-12-302022-12-312021-12-25
Debt / Equity 0.00.00.00.00.0
Current Ratio 1.31.41.51.31.2
Quick Ratio 0.80.91.00.90.9
Cash Flow
2025-12-272024-12-282023-12-302022-12-312021-12-25
Free Cash Flow $518M$502M$365M$295M$532M

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Institutional owners (13F) 617 filers · $7.8B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
82 (-8 vs prior Q) 61 (-20 vs prior Q) 180 (-11 vs prior Q) 201 (+13 vs prior Q) -972K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FMR LLC $737,350,307 3,251,247 9.42% Shares
VANGUARD CAPITAL MANAGEMENT LLC $714,227,026 3,149,288 9.12% Shares
HARRIS ASSOCIATES L P $508,269,048 2,241,144 6.49% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $501,427,927 2,210,979 6.40% Shares
STATE STREET CORP $422,800,968 1,864,284 5.40% Shares
DIMENSIONAL FUND ADVISORS LP $348,883,077 1,538,354 4.46% Shares
CITADEL ADVISORS LLC $270,696,771 1,193,601 3.46% Shares
GEODE CAPITAL MANAGEMENT, LLC $259,130,041 1,144,937 3.31% Shares
EARNEST PARTNERS LLC $254,007,295 1,120,011 3.24% Shares
WELLINGTON MANAGEMENT GROUP LLP $223,361,616 984,883 2.85% Shares
AMERIPRISE FINANCIAL INC $192,886,814 850,503 2.46% Shares
NEUBERGER BERMAN GROUP LLC $192,182,793 847,488 2.45% Shares
Clearbridge Investments, LLC $177,185,527 781,276 2.26% Shares
COOKE & BIELER LP $171,369,328 755,630 2.19% Shares
VICTORY CAPITAL MANAGEMENT INC $150,762,735 664,768 1.93% Shares
MILLENNIUM MANAGEMENT LLC $110,324,717 486,462 1.41% Shares
BANK OF AMERICA CORP /DE/ $104,921,899 462,639 1.34% Shares
Gotham Asset Management, LLC $98,233,181 433,146 1.25% Shares
Amundi $93,528,650 412,402 1.19% Shares
NORGES BANK $83,921,372 370,040 1.07% Shares
MARSHALL WACE, LLP $76,947,125 339,288 0.98% Shares
Iron Triangle Partners LP $75,748,141 379,728 0.97% Shares
ALLIANCEBERNSTEIN L.P. $64,615,913 374,585 0.83% Shares
SNYDER CAPITAL MANAGEMENT L P $63,899,443 281,756 0.82% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $63,174,169 278,558 0.81% Shares
BNP PARIBAS FINANCIAL MARKETS $63,095,473 278,211 0.81% Shares
VANGUARD FIDUCIARY TRUST CO $61,384,115 270,665 0.78% Shares
PRIMECAP MANAGEMENT CO/CA/ $60,523,448 266,870 0.77% Shares
GOLDMAN SACHS GROUP INC $57,319,812 252,744 0.73% Shares
Meridiem Capital Partners LP $56,012,367 246,979 0.72% Shares
Alyeska Investment Group, L.P. $53,295,650 235,000 0.68% Shares
Quantinno Capital Management LP $49,020,824 216,150 0.63% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $48,415,129 213,480 0.62% Shares
Boston Trust Walden Corp $46,506,918 205,066 0.59% Shares
Burgundy Asset Management Ltd. $45,453,909 278,329 0.58% Shares
SRS Investment Management, LLC $42,496,817 187,384 0.54% Shares
LOOMIS SAYLES & CO L P $38,517,487 169,838 0.49% Shares
JONES FINANCIAL COMPANIES LLLP $37,184,513 172,350 0.47% Shares
PERCEPTIVE ADVISORS LLC $31,750,600 140,000 0.41% Shares
LAKEWOOD CAPITAL MANAGEMENT, LP $30,389,860 134,000 0.39% Shares
NEW YORK STATE COMMON RETIREMENT FUND $29,879,583 131,750 0.38% Shares
BlackRock, Inc. $29,025,945 127,986 0.37% Shares
PICTON MAHONEY ASSET MANAGEMENT $26,340,305 116,144 0.34% Shares
FIL Ltd $25,184,576 111,048 0.32% Shares
Candriam S.C.A. $23,824,478 105,152 0.30% Shares
Clark Capital Management Group, Inc. $23,010,567 101,462 0.29% Shares
Vanguard Global Advisers, LLC $22,453,344 99,005 0.29% Shares
Swiss National Bank $22,452,210 99,000 0.29% Shares
CONFLUENCE INVESTMENT MANAGEMENT LLC $20,491,384 90,354 0.26% Shares
ENVESTNET ASSET MANAGEMENT INC $20,280,546 89,424 0.26% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $19,730,730 87,000 0.25% Call option
NOMURA HOLDINGS INC $19,672,672 86,744 0.25% Shares
RHUMBLINE ADVISERS $19,484,825 85,916 0.25% Shares
Ilex Capital Partners (UK) LLP $18,413,760 81,193 0.24% Shares
Aristotle Capital Boston, LLC $18,273,438 80,574 0.23% Shares
CITADEL ADVISORS LLC $17,485,509 77,100 0.22% Call option
NICHOLAS COMPANY, INC. $16,305,067 71,895 0.21% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $15,172,024 66,899 0.19% Shares
Mitsubishi UFJ Asset Management Co., Ltd. $15,164,087 66,864 0.19% Shares
Ranger Investment Management, L.P. $15,009,416 66,182 0.19% Shares
California Public Employees Retirement System $14,670,818 64,689 0.19% Shares
Assenagon Asset Management S.A. $14,020,385 61,821 0.18% Shares
ASSETMARK, INC $13,939,194 61,463 0.18% Shares
Rhenman & Partners Asset Management AB $12,972,388 57,200 0.17% Shares
RIVERBRIDGE PARTNERS LLC $12,859,587 56,703 0.16% Shares
TD Asset Management Inc $12,854,230 56,679 0.16% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $12,836,314 56,600 0.16% Put option
Laurus Investment Counsel Inc. $12,365,663 71,685 0.16% Shares
KING LUTHER CAPITAL MANAGEMENT CORP $12,204,023 53,812 0.16% Shares
FRONTIER CAPITAL MANAGEMENT CO LLC $11,552,133 50,938 0.15% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $10,732,081 47,278 0.14% Shares
RAYMOND JAMES FINANCIAL INC $10,506,727 46,328 0.13% Shares
VANGUARD ASSET MANAGEMENT, Ltd $10,472,482 46,177 0.13% Shares
KENNEDY CAPITAL MANAGEMENT LLC $9,914,950 43,719 0.13% Shares
BARCLAYS PLC $9,909,816 43,696 0.13% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $9,827,670 56,972 0.13% Shares
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $9,382,529 41,371 0.12% Shares
Park West Asset Management LLC $9,343,748 41,200 0.12% Shares
State of Tennessee, Department of Treasury $8,457,000 37,290 0.11% Shares
J.P. Marvel Investment Advisors, LLC $8,456,092 37,286 0.11% Shares
CASTLEARK MANAGEMENT LLC $8,174,646 36,045 0.10% Shares
JANE STREET GROUP, LLC $7,869,613 34,700 0.10% Call option
Pine Ridge Advisers LLC $7,710,860 34,000 0.10% Shares
PRUDENTIAL FINANCIAL INC $7,346,635 32,394 0.09% Shares
Capricorn Fund Managers Ltd $7,092,630 31,274 0.09% Shares
STATE OF WISCONSIN INVESTMENT BOARD $7,000,554 30,868 0.09% Shares
FIRST TRUST ADVISORS LP $6,951,290 30,651 0.09% Shares
Caption Management, LLC $6,803,700 30,000 0.09% Put option
Engineers Gate Manager LP $6,637,463 29,267 0.08% Shares
LAWSON KROEKER INVESTMENT MANAGEMENT INC/NE $6,351,027 28,004 0.08% Shares
Midwest Trust Co $6,091,126 26,858 0.08% Shares
VAN ECK ASSOCIATES CORP $5,942,578 26,203 0.08% Shares
SEI INVESTMENTS CO $5,929,630 26,150 0.08% Shares
Sendero Wealth Management, LLC $5,909,468 26,057 0.08% Shares
13D Management LLC $5,851,182 25,800 0.07% Shares
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $5,500,853 31,889 0.07% Shares
D. E. Shaw & Co., Inc. $5,462,691 24,087 0.07% Shares
INVESTMENT HOUSE LLC $5,447,042 24,018 0.07% Shares
LPL Financial LLC $5,409,169 23,851 0.07% Shares
LRT Capital Management, LLC $5,348,842 23,585 0.07% Shares

Company insiders 57 insiders · 21 officers · 27 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Glenn Coleman EVP & Chief Financial Officer May 29, 2026 A 27,752 0 0 $0
Flavia Pease Corporate Executive VP & CFO May 31, 2025 F 17,297 0 0 $0
David Ross Smith Corporate Executive VP & CFO March 3, 2022 M 25,819 0 0 $0
Davide Molho President & COO July 24, 2018 M 17,155 0 0 $0
Mark Mintz EVP, Chief Information Officer May 31, 2026 F 9,546 0 0 $0
William D Barbo Corporate Executive VP & CCO Nov. 7, 2024 G 23,337 0 0 $0
John W Kuo CEVP General Counsel & CCO June 1, 2020 A 3,171 0 0 $0
David P Johst Corporate Executive VP May 29, 2020 A 224,478 0 0 $0
John J Crowley SVP, Chief Accounting Officer Oct. 1, 2016 F 5,599 0 0 $0
Nancy Gillett Corporate Executive VP March 2, 2016 S 11,034 0 0 $0
Jorg Geller Corporate Executive VP Feb. 25, 2015 M 14,094 0 0 $0
RENAUD REAL H Corp. Executive VP Aug. 11, 2010 F 74,390 0 0 $0
Christopher Berthoux Executive Vice President Feb. 26, 2010 A 31,897 0 0 $0
Joanne P Acford Corp. Sr VP, GC and Corp. Sec Aug. 11, 2007 F 37,109 0 0 $0
David J Elliott Officer June 29, 2007 M 11,750 0 0 $0
Cheri L Walker Corporate Senior VP May 1, 2007 A 6,262 0 0 $0
Stephanie B Wells Senior Vice President April 2, 2007 A 11,500 0 0 $0
Nicholas Ventresca Senior Vice President April 2, 2007 F 12,713 0 0 $0
John C Ho Senior Vice President Feb. 23, 2007 A 12,710 0 0 $0
Brian Bathgate Corporate Vice President Feb. 27, 2006 S 16,134 0 0 $0
Alastair Stuart Mcewan Corporate VP Dec. 23, 2004 M 8,000 0 0 $0
Steven Barg Director June 2, 2026 A 3,287 0 0 $0
Nancy C Andrews Director May 12, 2026 G 3,964 0 0 $0
Reshema Kemps-Polanco Director May 8, 2026 A 4,563 0 0 $0
George Llado Director May 8, 2026 A 6,702 0 0 $0
Abraham Ceesay Director May 8, 2026 A 2,384 0 0 $0
Mark J Enyedy Director May 8, 2026 A 2,384 0 0 $0
Paul W Graves Director May 8, 2026 A 2,384 0 0 $0
Craig B. Thompson Director May 8, 2026 A 3,851 0 0 $0
Martin Mackay Director May 8, 2026 A 17,137 0 0 $0
Virginia M Wilson Director May 8, 2026 A 6,349 0 0 $0
George Massaro Director May 15, 2025 S 5,575 0 0 $0
Richard F Wallman Director Nov. 7, 2024 S 0 0 0 $0
Deborah Turner Kochevar Director May 13, 2024 A 7,894 0 0 $0
Robert J Bertolini Director May 13, 2024 A 32,802 0 0 $0
Richard C Reese Director May 15, 2023 A 65,541 0 0 $0
George M Milne JR Director May 7, 2021 A 29,079 0 0 $0
Stephen D Chubb Director Feb. 23, 2021 M 40,529 0 0 $0
Jean-Paul Mangeolle Director May 22, 2019 A 3,886 0 0 $0
William Waltrip Director Dec. 5, 2012 S 21,830 0 0 $0
Samuel O Thier MD Director May 9, 2012 A 18,230 0 0 $0
Douglas E Rogers Director May 7, 2010 A 12,859 0 0 $0
Nancy T Chang Director May 7, 2010 A 31,010 0 0 $0
Linda Mcgoldrick Director Feb. 13, 2006 A 0 0 $0
Walter S Nimmo Director Feb. 25, 2005 S 149,447 0 0 $0
John Urquhart Director Feb. 17, 2005 A 11,738 0 0 $0
Louise S Mccrary Director Feb. 17, 2005 A 0 0 $0
Robert Cawthorn Director June 2, 2004 G 278,600 0 0 $0
Shannon M Parisotto Aug. 11, 2026 M 4,807 0 2 $-2,365,755
Birgit Girshick Aug. 11, 2026 M 36,013 0 1 $-1,819,350

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 6 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
JANA PARTNERS LLC ×4 filings Aug. 4, 2011 Initial filing SEC
Relational Investors, LLC, Relational Investors Mid-Cap Fund I, L.P., Relational Investors Mid-Cap Fund II, L.P., Ralph V. Whitworth, David H. Batchelder, California State Teachers’ Retirement System ×3 filings Feb. 9, 2011 Initial filing SEC
Neuberger Berman Group LLC, Neuberger Berman LLC, Neuberger Berman Management ×3 filings Dec. 7, 2010 Initial filing SEC
Undisclosed reporting person June 16, 2010 Initial filing SEC
Undisclosed reporting person June 7, 2010 Initial filing Passive investment SEC
Charles River Laboratories International, Inc. IRS No. 061397316 May 5, 2010 Initial filing Board campaign SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 134 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
HTEC · EXCHANGE TRADED CONCEPTS TRUST 1.49% 4,749 NS April 30, 2026 N-PORT
EPSB · Harbor ETF Trust 1.33% 370 NS April 30, 2026 N-PORT
EPMV · Harbor ETF Trust 1.09% 291 NS April 30, 2026 N-PORT
EPSV · Harbor ETF Trust 0.90% 270 NS April 30, 2026 N-PORT
TAX · EA Series Trust 0.80% 1,131 NS May 29, 2026 N-PORT
LSEQ · Harbor ETF Trust 0.66% 612 NS April 30, 2026 N-PORT
HIBL · Direxion Shares ETF Trust 0.50% 2,356 NS April 30, 2026 N-PORT
FNY · First Trust Exchange-Traded AlphaDE… 0.38% 11,925 NS April 30, 2026 N-PORT
IQSM · New York Life Investments ETF Trust 0.33% 6,161 NS April 30, 2026 N-PORT
FFSM · FIDELITY COVINGTON TRUST 0.29% 22,440 NS April 30, 2026 N-PORT
DFAT · Dimensional ETF Trust 0.26% 212,321 NS April 30, 2026 N-PORT
BKMC · BNY Mellon ETF Trust 0.22% 8,115 NS April 30, 2026 N-PORT
FSMD · FIDELITY COVINGTON TRUST 0.17% 24,528 NS April 30, 2026 N-PORT
SCHM · SCHWAB STRATEGIC TRUST 0.17% 133,341 NS May 31, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.16% 138,243 NS April 30, 2026 N-PORT
BBMC · J.P. Morgan Exchange-Traded Fund Tr… 0.15% 18,369 NS April 30, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.15% 6,079 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.13% 22,674 NS April 30, 2026 N-PORT
DFSV · Dimensional ETF Trust 0.13% 59,338 NS April 30, 2026 N-PORT
RXL · ProShares Trust 0.13% 513 NS May 31, 2026 N-PORT
REVS · Columbia ETF Trust I 0.12% 2,082 NS April 30, 2026 N-PORT
CURE · Direxion Shares ETF Trust 0.12% 982 NS April 30, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.11% 3,280 NS April 30, 2026 N-PORT
FBCV · FIDELITY COVINGTON TRUST 0.11% 1,032 NS April 30, 2026 N-PORT
AVMC · AMERICAN CENTURY ETF TRUST 0.09% 1,986 NS May 31, 2026 N-PORT
FNX · First Trust Exchange-Traded AlphaDE… 0.07% 5,261 NS April 30, 2026 N-PORT
RECS · Columbia ETF Trust I 0.06% 20,810 NS April 30, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.06% 1,328 NS April 30, 2026 N-PORT
SPXD · DBX ETF Trust 0.05% 19 NS May 31, 2026 N-PORT
DFUV · Dimensional ETF Trust 0.05% 41,210 NS April 30, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.04% 105,382 NS April 30, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.03% 5,627 NS April 30, 2026 N-PORT
SCHV · SCHWAB STRATEGIC TRUST 0.03% 24,676 NS May 31, 2026 N-PORT
GVUS · Goldman Sachs ETF Trust 0.03% 591 NS May 31, 2026 N-PORT
SNPE · DBX ETF Trust 0.02% 3,759 NS May 29, 2026 N-PORT
EGLE · Global X Funds 0.02% 3 NS April 30, 2026 N-PORT
CHRI · Global X Funds 0.02% 7 NS April 30, 2026 N-PORT
DEUS · DBX ETF Trust 0.02% 337 NS May 29, 2026 N-PORT
SPXT · ProShares Trust 0.02% 328 NS May 31, 2026 N-PORT
FNDX · SCHWAB STRATEGIC TRUST 0.02% 30,460 NS May 31, 2026 N-PORT
QRFT · Exchange Listed Funds Trust 0.02% 19 NS April 30, 2026 N-PORT
FNDB · SCHWAB STRATEGIC TRUST 0.02% 1,472 NS May 31, 2026 N-PORT
SPUS · Tidal Trust I 0.02% 3,014 NS May 31, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.02% 2,431 NS April 30, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.02% 10,974 NS April 30, 2026 N-PORT
SPXN · ProShares Trust 0.02% 69 NS May 31, 2026 N-PORT
JUST · Goldman Sachs ETF Trust 0.01% 455 NS May 31, 2026 N-PORT
SPXE · ProShares Trust 0.01% 67 NS May 31, 2026 N-PORT
DSPY · Tema ETF Trust 0.01% 697 NS May 31, 2026 N-PORT
XRMI · Global X Funds 0.01% 41 NS April 30, 2026 N-PORT