CRL Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $290.19
Market Cap (MRQ) $13.85B
P/E (TTM) -60.5
EPS (TTM) $-4.80
Revenue (TTM) $4.00B
ROE (TTM) -7.7%
Debt/Equity (MRQ) 0.0
52W Range $146–$303

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About Charles River Laboratories International, Inc. Common Stock Company overview from Wikipedia

05 · wikidata

Charles River Laboratories International, Incorporated is an American life sciences company and contract research organisation (CRO) headquartered in Wilmington, Massachusetts, United States. Founded in 1947, the company provides goods and services that support the development of drugs, vaccines, and other therapeutics. Its operations span at least 20 countries, offering research models, drug discovery and safety assessment, and manufacturing and testing services to pharmaceutical, biotechnology, government, and other clients.

Charles River Laboratories is a global provider of non-clinical drug development services, known for its role in toxicology studies, research animal models, and microbial testing services used in regulatory submissions to health authorities such as the U.S. Food and Drug Administration (FDA). The company has also been the subject of public scrutiny and regulatory attention over its use of research animals, including dogs, primates, and horseshoe crabs.

As of 2024, the company employs over 20,000 people worldwide and is publicly traded on the New York Stock Exchange under the ticker symbol CRL.

History

Charles River was founded in 1947 by Henry Foster, a young veterinarian who purchased one thousand rat cages from a Virginia farm and set up a one-person laboratory in Boston overlooking the Charles River. He supplied local researchers with laboratory animals.

In 1955, the company's headquarters were relocated to their current home in Wilmington, Massachusetts. The organization became an international entity in 1966 by opening a new animal production facility in France.

The first commercial, comprehensive genetic monitoring program was implemented by Charles River in 1981. Three years later, they were acquired by Bausch & Lomb. In 1988, the organization began creating transgenic mice and rats. In the 1990s, they began in vitro endotoxin testing. In the 1990s, Jim Foster bought Charles River back from Bausch & Lomb, and the company later went public on the New York Stock Exchange.

Charles River launched the Humane Care Imperative in 2002, designed to raise awareness and train employees on animal welfare's importance. The same year, they were named "Company of the Year" by The Boston Globe. The company introduced preconditioning services in 2005 to provide customers with study-ready animals.

In 2008, Charles River signed a ten-year contract to partner with the National Cancer Institute and opened a facility in Frederick, Maryland.

In April 2019, Charles River announced it would cease its San Diego operations, moving the breeding of rodents for testing compounds to Hollister, California.

In March 2023, the Born Free USA animal welfare organization protested against Charles River's plan to export 1,000 endangered juvenile long-tail macaques to Cambodia for testing.

Acquisitions

In 1988, Charles River purchased Specific Pathogen Antigen Free Avian Services (SPAFAS) and serologic diagnostic services Merck, Sharp, and Dohme.

Between 1996 and 2000, the company acquired Endosafe, Inc. and Sierra Biomedical.

In October 2003, Charles River Laboratories merged with Inveresk, a research company based in the United Kingdom. The company was known then as Charles River Laboratories. Inveresk specialised in clinical research and pre-clinical testing, and their main facilities are in Edinburgh, Scotland. In late 2009, Charles River sold its Clinical Services Division in Edinburgh to Quotient Bioresearch.

In 2010, Charles River Laboratories attempted to acquire WuXi PharmaTech, a China-based contract research organization, but the offer was withdrawn when the deal faced opposition from several large Charles River investors, including Relational Investors, JANA Partners, and Neuberger Berman. The proxy advisory firm RiskMetrics had also recommended that Charles River's shareholders vote against the proposed deal.

From 2008 to 2013, Charles River acquires several companies including NewLab Bioquality AG, MIR Preclinical Services, Piedmont Research Center, LLC, Cerebricon, Ltd., Accugenix, and Vital River, allowing the company to expand their research models and services portfolio to drug development and discovery markets in China.

The acquisitions of Argenta and BioFocus in 2014 allowed Charles River to establish itself as a full-service, early-stage contract research organization with integrated in vitro and in vivo capabilities from target discovery through pre-clinical development.

In July 2015, the company announced it would acquire Celsis International for $212 million.

In 2016, the company announced it was set to acquire WIL Research for approximately $585 million in cash and Blue Stream Laboratories.

In August 2017, the business announced it would acquire Brains On-Line.

In January 2018, the company announced it would acquire KWS BioTest for up to £18 million ($24.4 million). In February of the same year, Charles River announced it would acquire MPI Research for approximately $800 million in cash. The transaction was completed on April 3, 2018.

In February 2019, the company announced it would acquire Citoxlab for €448 million in cash (approximately $500 million), including the former acquisitions of the French company, AccelLAB, Atlanbio and Solvo Biotechnology. The transaction was completed on April 29. In December of the same year the business announced it would acquire HemaCare for approximately $380 million in cash.

In August 2020, the company announced it would acquire Cellero for $38 million in cash.

In January 2021, the company announced it would acquire Distributed Bio, Inc., an antibody discovery business.

In February 2021, Charles River announced it would acquire Cognate BioServices, Inc. for $875 million.

In March 2021, Charles River announced the acquisition of Retrogenix for $48 million.

In May 2021, Charles River announced the acquisition of Vigene Biosciences, a gene therapy contract development and manufacturing organization (CDMO), for $292.5 million.

In October 2021, a Japanese subsidiary of Charles River was acquired by Jackson Laboratory for $63M.

In April 2022, the company announced it would acquire Explora BioLabs.

In January 2023, the business announced it would acquire SAMDI Tech, Inc.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

sectorHealthcare industryLife Sciences Tools & Services employees18,300 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$4.02B
2016-12-31 → 2025-12-27
EPS$-2.91
2016-12-31 → 2025-12-27
Free Cash Flow$518M
2016-12-31 → 2025-12-27
Net margin-6.0%
2016-12-31 → 2025-12-27
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend CRL 5Y avg Peer Median Verdict
P/E (TTM) -60.55Y avg ≈191.6 ≈191.6 · ·
P/S (TTM) 3.55Y avg ≈3.2 ≈3.2 4.9 Undervalued
P/B (MRQ) 4.95Y avg ≈4.1 ≈4.1 3.6 Fair value
EV / EBITDA 32.85Y avg ≈16.9 ≈16.9 25.4 Undervalued
Price / FCF (TTM) 37.45Y avg ≈28.8 ≈28.8 · ·
Price / Cash Flow (TTM) 23.85Y avg ≈17.3 ≈17.3 26.2 Undervalued
EV / Revenue 3.55Y avg ≈3.1 ≈3.1 · ·
EV / FCF 27.15Y avg ≈28.3 ≈28.3 · ·
Price / Tangible Book (MRQ) 5.4 · · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 8.9%
Next Report Nov 03, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 12, 2026 $3.02 $2.76 9.2%
March 31, 2026 $2.06 $1.96 5.0%
Dec. 31, 2025 $2.39 $2.37 0.98%
Sept. 30, 2025 $2.43 $2.36 2.9%
June 30, 2025 $3.12 $2.52 23.7%
March 31, 2025 $2.34 $2.10 11.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 15
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $4.02B$4.05B$4.13B$3.98B$3.54B$2.92B$2.62B$2.27B$1.86B$1.68B$1.36B$1.30B
Cost of Revenue ········$290M$277M$264M$266M
SG&A Expense $743M$751M$748M$665M$620M$529M$518M$444M$371M$365M$300M$269M
Operating Income $25M$227M$617M$651M$590M$433M$351M$331M$288M$238M$206M$178M
Interest Expense ··$137M$59M$74M$86M$61M$64M$30M$28M$15M$12M
Interest Income $5M$9M$5M$780.0K$652.0K$834.0K$2M$812.0K$690.0K$1M$1M$1M
Other Non-op $-23M$-17M$96M$31M$-36M$100M$12M$13M$38M$12M$3M$11M
Pretax Income $-100M$93M$581M$623M$481M$447M$304M$282M$297M$223M$195M$178M
Income Tax $43M$68M$101M$130M$82M$82M$50M$54M$171M$67M$43M$48M
Net Income $-144M$22M$475M$486M$391M$364M$252M$226M$123M$155M$149M$127M
EPS (Basic) $-2.91$0.20$9.27$9.57$7.77$7.35$5.17$4.72$2.60$3.29$3.21$2.72
EPS (Diluted) $-2.91$0.20$9.22$9.48$7.60$7.20$5.07$4.62$2.54$3.23$3.13$2.66
Shares (Basic) 49,564,00051,380,00051,227,00050,812,00050,293,00049,550,00048,730,00047,947,00047,481,00047,014,00046,496,00046,627,000
Shares (Diluted) 49,564,00051,628,00051,451,00051,301,00051,425,00050,611,00049,693,00049,018,00048,564,00047,958,00047,634,00047,558,000
EBITDA $428M$589M$931M$955M$855M$668M$549M$493M$419M$364M$301M$274M
Balance Sheet 30
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $214M$195M$277M$234M$241M$228M$238M$195M$164M$118M$118M$160M
Short-term Investments ····$1M$1M$941.0K$885.0K$28M$4M$21M·
Receivables $709M$721M$780M$752M$643M$618M$514M$472M$430M$364M$270M$258M
Inventory $299M$279M$380M$256M$199M$186M$161M$128M$115M$96M$94M$89M
Prepaid Expense $129M$106M$83M$108M$97M$73M$56M$49M$81M$45M$47M$45M
Other Current Assets ·····$0$300.0K$300.0K$0$45M$47M$73M
Current Assets $1.45B$1.40B$1.61B$1.44B$1.27B$1.20B$1.02B$898M$827M$657M$559M$579M
PP&E (Net) $1.66B$1.60B$1.64B$1.47B$1.29B$1.12B$1.04B$933M$782M$756M$678M$677M
PP&E (Gross) $3.19B$3.06B$2.98B$2.63B$2.39B$2.21B$2.02B$1.81B$1.58B$1.46B$1.32B$1.33B
Accum. Depreciation $1.54B$1.45B$1.34B$1.16B$1.10B$1.09B$978M$874M$801M$706M$645M$655M
Goodwill $2.76B$2.85B$3.10B$2.85B$2.71B$1.81B$1.54B$1.25B$805M$788M$439M$321M
Intangibles $340M$723M$864M$955M$1.06B$788M$689M$611M$370M$394M$281M$281M
Other Non-current Assets $293M$278M$309M$148M$152M$353M$213M$144M$124M$88M$72M$73M
Total Assets $7.14B$7.53B$8.20B$7.60B$7.02B$5.49B$4.69B$3.86B$2.93B$2.71B$2.07B$1.87B
Accounts Payable $149M$140M$169M$206M$198M$122M$111M$66M$78M$68M$37M$34M
Accrued Liabilities $270M$232M$228M$220M$229M$150M$139M$107M$90M$84M$89M$67M
Current Liabilities $1.12B$994M$1.06B$1.09B$1.03B$840M$710M$558M$464M$430M$312M$295M
Capital Leases $434M$484M$419M$390M$253M$156M$116M·····
Deferred Tax $95M$107M$191M$216M$240M$217M$167M$144M$90M$56M$48M$23M
Other Non-current Liabilities $138M$195M$223M$175M$243M$205M$183M$179M$195M$159M$89M$100M
Total Liabilities $3.92B$4.02B$4.54B$4.58B$4.43B$3.35B$3.03B$2.52B$1.87B$1.86B$1.30B$1.17B
Long-term Debt ·······$1.61B$1.09B$1.18B$814M$717M
Total Debt $166.0K$155.0K$3M$1M$101.0K$47M$36M$1.65B$1.12B$1.21B$836M$754M
Common Stock $492.0K$511.0K$513.0K$509.0K$505.0K$498.0K$489.0K$482.0K$875.0K$863.0K$855.0K$845.0K
Retained Earnings $1.39B$1.81B$1.89B$1.43B$981M$625M$280M$42M$289M$165M$11M$-139M
Treasury Stock $0$0$0$0$0$0$0$55.0K$1.66B$1.55B$1.54B$1.42B
AOCI $-172M$-317M$-196M$-262M$-165M$-139M$-178M$-173M$-145M$-254M$-136M$-74M
Stockholders' Equity $3.16B$3.46B$3.60B$2.98B$2.53B$2.11B$1.63B$1.32B$1.05B$837M$733M$672M
Liabilities + Equity $7.14B$7.53B$8.20B$7.60B$7.02B$5.49B$4.69B$3.86B$2.93B$2.71B$2.07B$1.87B
Shares Outstanding 49,217,00051,141,00051,338,00050,944,00050,480,00049,767,00048,936,00048,209,00047,402,00047,363,00046,698,00047,327,000
Cash Flow 18
Metric Trend 202520242023202220212020201920182017201620152014
D&A $403M$362M$314M$304M$266M$235M$198M$162M$131M$127M$95M$96M
Stock-based Comp $71M$70M$72M$74M$71M$56M$57M$47M$44M$44M$40M$31M
Deferred Tax $-75M$-67M$-51M$-33M$-20M$2M$-21M$-10M$28M$3M$4M$9M
Amort. of Intangibles $179M$138M$137M$147M$125M$112M$90M$65M$41M$42M$24M$26M
Restructuring $100M$107M$30M$8M$7M$13M$14M$10M$5M$18M$8M$8M
Other Non-cash $483M$348M$-126M$-211M$53M$-111M$-5M$16M$-8M$-28M$-395.0K·
Operating Cash Flow $738M$735M$684M$620M$761M$547M$481M$441M$318M$317M$307M$252M
CapEx $219M$233M$319M$325M$229M$167M$141M$140M$82M$55M$63M$57M
Investing Cash Flow $-209M$-245M$-563M$-608M$-1.44B$-602M$-682M$-955M$-73M$-693M··
Debt Issued $1.23B$1.08B$776M$2.95B$6.95B$2.23B$3.36B$2.76B$237M$1.04B··
Net Debt Issued $1.23B$1.08B$776M$2.95B$6.95B$2.23B$3.36B$2.76B····
Stock Repurchased $361M$119M$24M$39M$41M$24M$18M$14M$107M$12M$117M$122M
Net Stock Activity $-361M$-119M$-24M$-39M$-41M$-24M$-18M$-14M$-107M$-12M$-117M$-122M
Financing Cash Flow $-537M$-551M$-86M$-42M$673M$47M$232M$558M$-208M$381M··
Net Change in Cash $10M$-79M$43M$-5M$13M$-7M$43M$31M$46M$-69.0K$-43M$4M
Taxes Paid $120M$126M$90M$76M$75M$60M$54M$68M····
Free Cash Flow $518M$502M$365M$295M$532M$380M$340M$301M$236M$245M$225M$195M
Levered FCF ··$252M$248M$471M$309M$290M$250M$223M$226M$213M$186M
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 0.63%5.6%14.9%16.4%16.7%14.8%13.4%14.6%15.5%14.1%15.1%13.7%
Net Margin -3.6%0.55%11.5%12.2%11.0%12.5%9.6%10.0%6.6%9.2%10.9%·
Pretax Margin -2.5%2.3%14.1%15.7%13.6%15.3%11.6%12.4%16.0%13.3%14.3%13.7%
EBITDA Margin 10.7%14.5%22.6%24.0%24.2%22.8%20.9%21.8%22.5%21.6%22.1%21.1%
ROA -2.0%0.28%6.0%6.7%6.2%7.1%5.9%6.7%4.4%6.5%7.6%·
ROE -4.4%0.63%14.4%17.6%16.8%19.4%17.1%19.2%13.1%19.7%21.2%·
ROIC 1.1%1.8%14.2%17.3%19.3%16.4%17.6%9.0%5.6%8.1%10.2%9.1%
Liquidity & Solvency 5
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 1.31.41.51.31.21.41.41.61.81.51.82.0
Quick Ratio 0.80.91.00.90.91.01.11.21.31.11.21.4
Debt / Equity 0.00.00.00.00.00.00.01.31.11.41.11.1
LT Debt / Equity ·······1.21.01.41.11.1
Interest Coverage ··4.511.08.05.05.85.29.78.613.714.9
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.50.50.50.50.60.60.60.70.70.70.70.7
Inventory Turnover ········2.72.92.93.0
Receivables Turnover 5.65.45.45.75.65.25.35.04.75.35.25.4
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $64.30$67.69$70.06$58.42$50.21$42.49$33.40$27.33$22.05$17.67$15.70$14.20
Revenue / Share $81.01$78.45$80.26$77.50$68.84$57.77$52.75$46.23$38.25$35.06··
Cash Flow / Share $14.88$14.23$13.29$12.08$14.79$10.80$9.68$9.00$6.55$6.26··
Cash / Share $4.34$3.81$5.39$4.59$4.78$4.59$4.86$4.05$3.46$2.48$2.53$3.38
EPS (TTM) $-2.91$0.20$9.22$9.48$7.60$7.20$5.07$4.62$2.54$3.23$3.13$2.66
Growth Rates 7
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY -0.85%-1.9%3.9%12.3%21.1%·······
Revenue CAGR 3Y 0.33%4.6%12.2%·········
Revenue CAGR 5Y 6.6%···········
EPS YoY ·-97.8%-2.7%24.7%5.6%·······
EPS CAGR 3Y ·-70.3%8.6%·········
Net Income YoY ·-95.3%-2.4%24.4%7.3%·······
Net Income CAGR 3Y ·-61.6%9.2%·········
Valuation (TTM) 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $4.02B$4.05B$4.13B$3.98B$3.54B$2.92B$2.62B$2.27B$1.86B$1.68B$1.36B$1.30B
Net Income TTM $-144M$22M$475M$486M$391M$364M$252M$226M$123M$155M$149M$127M
Market Cap $10.02B$9.52B$12.14B$11.10B$18.64B$12.53B$7.43B$5.39B$5.19B$3.61B$3.74B$3.04B
Enterprise Value $9.81B$9.33B$11.86B$10.87B$18.40B$12.34B$7.23B$6.84B$6.12B$4.70B$4.46B$3.64B
P/E -70.0930.825.623.048.635.030.024.243.123.625.624.2
P/S 2.52.42.92.85.34.32.82.42.82.12.72.3
P/B 3.22.83.43.77.45.94.54.15.04.35.14.5
P / Tangible Book 166.0···········
P / Cash Flow 13.613.017.717.924.522.915.512.216.312.013.012.1
P / FCF 19.319.033.237.635.033.021.817.922.014.716.615.6
EV / EBITDA 22.915.812.711.421.518.513.213.914.612.914.813.3
EV / FCF 18.918.632.536.934.632.521.222.726.019.219.818.6
EV / Revenue 2.42.32.92.75.24.22.83.03.32.83.32.8
Earnings Yield -1.4%0.11%3.9%4.3%2.1%2.9%3.3%4.1%2.3%4.2%3.9%4.1%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-272024-12-282023-12-302022-12-312021-12-25
Revenue $4.02B $4.05B $4.13B $3.98B $3.54B
Operating Margin % 0.63% 5.6% 14.9% 16.4% 16.7%
Net Income $-144M $22M $475M $486M $391M
Diluted EPS $-2.91 $0.20 $9.22 $9.48 $7.60

Institutional owners (13F) 607 filers · $13.6B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 607
Value held $13.6B
New positions 74
Exited positions 62
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
74 (-17 vs prior Q) 62 (-19 vs prior Q) 193 (0 vs prior Q) 204 (+13 vs prior Q) +2.8M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
VANGUARD GROUP INC $1,174,373,670 5,887,175 8.65% Shares
FMR LLC $961,533,236 4,239,752 7.09% Shares
BlackRock, Inc. $861,475,349 3,798,560 6.35% Shares
VANGUARD CAPITAL MANAGEMENT LLC $714,227,026 3,149,288 5.26% Shares
Invesco Ltd. $676,919,391 2,984,785 4.99% Shares
HARRIS ASSOCIATES L P $508,269,048 2,241,144 3.75% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $501,427,927 2,210,979 3.70% Shares
Allspring Global Investments Holdings, LLC $436,473,035 1,905,247 3.22% Shares
STATE STREET CORP $422,800,968 1,864,284 3.12% Shares
DIMENSIONAL FUND ADVISORS LP $373,848,597 1,648,450 2.76% Shares
ARIEL INVESTMENTS, LLC $341,587,697 1,506,185 2.52% Shares
GEODE CAPITAL MANAGEMENT, LLC $295,598,099 1,305,738 2.18% Shares
WELLINGTON MANAGEMENT GROUP LLP $292,210,525 1,288,463 2.15% Shares
CITADEL ADVISORS LLC $270,696,771 1,193,601 1.99% Shares
BANK OF AMERICA CORP /DE/ $265,930,779 1,172,586 1.96% Shares
EARNEST PARTNERS LLC $254,007,295 1,120,011 1.87% Shares
AMERIPRISE FINANCIAL INC $199,834,979 881,189 1.47% Shares
NEUBERGER BERMAN GROUP LLC $195,633,630 862,704 1.44% Shares
SEI INVESTMENTS CO $184,499,540 813,530 1.36% Shares
MORGAN STANLEY $181,542,851 800,487 1.34% Shares
Clearbridge Investments, LLC $177,185,527 781,276 1.31% Shares
COOKE & BIELER LP $171,369,328 755,630 1.26% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $157,642,604 682,173 1.16% Shares
VICTORY CAPITAL MANAGEMENT INC $150,762,735 664,768 1.11% Shares
UBS Group AG $146,675,752 646,747 1.08% Shares
GOLDMAN SACHS GROUP INC $145,100,822 639,803 1.07% Shares
MILLENNIUM MANAGEMENT LLC $110,324,717 486,462 0.81% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $106,061,291 467,663 0.78% Shares
BANK OF MONTREAL /CAN/ $104,270,783 459,768 0.77% Shares
NORTHERN TRUST CORP $101,169,205 446,092 0.75% Shares
Gotham Asset Management, LLC $98,233,181 433,146 0.72% Shares
Amundi $93,528,650 412,402 0.69% Shares
NORGES BANK $83,921,372 370,040 0.62% Shares
MARSHALL WACE, LLP $77,787,835 342,995 0.57% Shares
Iron Triangle Partners LP $75,748,141 379,728 0.56% Shares
CITIGROUP INC $71,714,853 316,217 0.53% Shares
BNP PARIBAS FINANCIAL MARKETS $69,108,583 304,725 0.51% Shares
Bank of New York Mellon Corp $69,054,385 304,486 0.51% Shares
Boston Trust Walden Corp $65,523,486 288,917 0.48% Shares
JPMORGAN CHASE & CO $65,085,033 286,317 0.48% Shares
ALLIANCEBERNSTEIN L.P. $64,615,913 374,585 0.48% Shares
SNYDER CAPITAL MANAGEMENT L P $63,899,443 281,756 0.47% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $63,174,169 278,558 0.47% Shares
DEUTSCHE BANK AG\ $62,723,084 276,569 0.46% Shares
VANGUARD FIDUCIARY TRUST CO $61,384,115 270,665 0.45% Shares
PRIMECAP MANAGEMENT CO/CA/ $60,523,448 266,870 0.45% Shares
RAYMOND JAMES FINANCIAL INC $58,234,910 256,779 0.43% Shares
Meridiem Capital Partners LP $56,012,367 246,979 0.41% Shares
Alyeska Investment Group, L.P. $53,295,650 235,000 0.39% Shares
LOOMIS SAYLES & CO L P $50,725,593 223,668 0.37% Shares

Show all 607 institutional owners →

Activists & 5%+ owners 6 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
JANA PARTNERS LLC ×4 filings Aug. 4, 2011 · Initial filing · SEC
Relational Investors, LLC, Relational Investors Mid-Cap Fund I, L.P., Relational Investors Mid-Cap Fund II, L.P., Ralph V. Whitworth, David H. Batchelder, California State Teachers’ Retirement System ×3 filings Feb. 9, 2011 · Initial filing · SEC
Neuberger Berman Group LLC, Neuberger Berman LLC, Neuberger Berman Management ×3 filings Dec. 7, 2010 · Initial filing · SEC
Undisclosed reporting person June 16, 2010 · Initial filing · SEC
Undisclosed reporting person June 7, 2010 · Initial filing Passive investment SEC
Charles River Laboratories International, Inc. IRS No. 061397316 May 5, 2010 · Initial filing Board campaign SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 57 insiders · 23 officers · 29 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Birgit Girshick Chief Executive Officer Aug. 19, 2026 G 35,485 0 1 $-1,819,350
Glenn Coleman EVP & Chief Financial Officer Sept. 30, 2026 P 27,762 1 0 $2,974
Flavia Pease Corporate Executive VP & CFO May 31, 2025 F 17,297 0 0 $0
David Ross Smith Corporate Executive VP & CFO March 3, 2022 M 25,819 0 0 $0
Davide Molho President & COO July 24, 2018 M 17,155 0 0 $0
Shannon M Parisotto CEVP, Disc & Safety Assessment Aug. 19, 2026 M 4,807 0 3 $-2,965,466
Mark Mintz EVP, Chief Information Officer May 31, 2026 F 9,546 0 0 $0
William D Barbo Corporate Executive VP & CCO Nov. 7, 2024 G 23,337 0 0 $0
John W Kuo CEVP General Counsel & CCO June 1, 2020 A 3,171 0 0 $0
David P Johst Corporate Executive VP May 29, 2020 A 224,478 0 0 $0
John J Crowley SVP, Chief Accounting Officer Oct. 1, 2016 F 5,599 0 0 $0
Nancy Gillett Corporate Executive VP March 2, 2016 S 11,034 0 0 $0
Jorg Geller Corporate Executive VP Feb. 25, 2015 M 14,094 0 0 $0
RENAUD REAL H Corp. Executive VP Aug. 11, 2010 F 74,390 0 0 $0
Christopher Berthoux Executive Vice President Feb. 26, 2010 A 31,897 0 0 $0
Joanne P Acford Corp. Sr VP, GC and Corp. Sec Aug. 11, 2007 F 37,109 0 0 $0
David J Elliott Officer June 29, 2007 M 11,750 0 0 $0
Cheri L Walker Corporate Senior VP May 1, 2007 A 6,262 0 0 $0
Stephanie B Wells Senior Vice President April 2, 2007 A 11,500 0 0 $0
Nicholas Ventresca Senior Vice President April 2, 2007 F 12,713 0 0 $0
John C Ho Senior Vice President Feb. 23, 2007 A 12,710 0 0 $0
Brian Bathgate Corporate Vice President Feb. 27, 2006 S 16,134 0 0 $0
Alastair Stuart Mcewan Corporate VP Dec. 23, 2004 M 8,000 0 0 $0
James C Foster Director Aug. 25, 2026 M 31,596 0 3 $-34,844,875
Nancy C Andrews Director Aug. 18, 2026 M 1,438 0 1 $-163,443
Steven Barg Director June 2, 2026 A 3,287 0 0 $0
Reshema Kemps-Polanco Director May 8, 2026 A 4,563 0 0 $0
George Llado Director May 8, 2026 A 6,702 0 0 $0
Abraham Ceesay Director May 8, 2026 A 2,384 0 0 $0
Mark J Enyedy Director May 8, 2026 A 2,384 0 0 $0
Paul W Graves Director May 8, 2026 A 2,384 0 0 $0
Craig B. Thompson Director May 8, 2026 A 3,851 0 0 $0
Martin Mackay Director May 8, 2026 A 17,137 0 0 $0
Virginia M Wilson Director May 8, 2026 A 6,349 0 0 $0
George Massaro Director May 15, 2025 S 5,575 0 0 $0
Richard F Wallman Director Nov. 7, 2024 S 0 0 0 $0
Deborah Turner Kochevar Director May 13, 2024 A 7,894 0 0 $0
Robert J Bertolini Director May 13, 2024 A 32,802 0 0 $0
Richard C Reese Director May 15, 2023 A 65,541 0 0 $0
George M Milne JR Director May 7, 2021 A 29,079 0 0 $0
Stephen D Chubb Director Feb. 23, 2021 M 40,529 0 0 $0
Jean-Paul Mangeolle Director May 22, 2019 A 3,886 0 0 $0
William Waltrip Director Dec. 5, 2012 S 21,830 0 0 $0
Samuel O Thier MD Director May 9, 2012 A 18,230 0 0 $0
Douglas E Rogers Director May 7, 2010 A 12,859 0 0 $0
Nancy T Chang Director May 7, 2010 A 31,010 0 0 $0
Linda Mcgoldrick Director Feb. 13, 2006 A · 0 0 $0
Walter S Nimmo Director Feb. 25, 2005 S 149,447 0 0 $0
John Urquhart Director Feb. 17, 2005 A 11,738 0 0 $0
Louise S Mccrary Director Feb. 17, 2005 A · 0 0 $0
Robert Cawthorn Director June 2, 2004 G 278,600 0 0 $0
Joseph W Laplume · Aug. 10, 2026 G 31,041 1 1 $-61,124
Victoria L Creamer · Aug. 6, 2026 M 30,051 0 1 $-1,083,030
Michael Gunnar Knell · Aug. 6, 2026 M 11,852 0 9 $-1,730,250
Thomas F Ackerman · Feb. 29, 2016 F 111,346 0 0 $0
Dennis R Shaughnessy · Nov. 29, 2004 G 35,511 0 0 $0
Michael F Ankcorn · Nov. 4, 2004 S 0 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 108 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
EPSB · Harbor ETF Trust 2.15% 443 NS July 31, 2026 N-PORT
PTH · Invesco Exchange-Traded Fund Trust 2.00% 20,123 SH Oct. 2, 2026 Daily
HTEC · EXCHANGE TRADED CONCEPTS TRUST 1.71% 5,092 NS July 31, 2026 N-PORT
RSPH · Invesco Exchange-Traded Fund Trust 1.70% 51,688 SH Oct. 2, 2026 Daily
EPSV · Harbor ETF Trust 1.59% 415 NS July 31, 2026 N-PORT
EPMV · Harbor ETF Trust 1.44% 291 NS July 31, 2026 N-PORT
ALTL · Pacer Funds Trust 1.09% 4,303 NS July 31, 2026 N-PORT
IBB · iShares Trust 0.96% 363,741 SH Sept. 11, 2026 Daily
LSEQ · Harbor ETF Trust 0.93% 614 NS July 31, 2026 N-PORT
HIBL · Direxion Shares ETF Trust 0.74% 2,375 NS July 31, 2026 N-PORT
JDOC · J.P. Morgan Exchange-Traded Fund Tr… 0.66% 259 NS July 31, 2026 N-PORT
SPHB · Invesco Exchange-Traded Fund Trust … 0.66% 22,191 SH Oct. 2, 2026 Daily
PDP · Invesco Exchange-Traded Fund Trust 0.66% 33,984 SH Oct. 2, 2026 Daily
PALC · Pacer Funds Trust 0.61% 5,509 NS July 31, 2026 N-PORT
FNY · First Trust Exchange-Traded AlphaDE… 0.49% 12,141 NS July 31, 2026 N-PORT
IQSM · New York Life Investments ETF Trust 0.45% 6,439 NS July 31, 2026 N-PORT
PKW · Invesco Exchange-Traded Fund Trust 0.42% 24,876 SH Oct. 2, 2026 Daily
FFSM · FIDELITY COVINGTON TRUST 0.40% 25,814 NS July 31, 2026 N-PORT
DFAT · Dimensional ETF Trust 0.34% 209,615 NS July 31, 2026 N-PORT
BKMC · BNY Mellon ETF Trust 0.28% 7,783 NS July 31, 2026 N-PORT
ESML · iShares Trust 0.24% 25,082 SH Sept. 11, 2026 Daily
BBMC · J.P. Morgan Exchange-Traded Fund Tr… 0.24% 20,898 NS July 31, 2026 N-PORT
FSMD · FIDELITY COVINGTON TRUST 0.24% 25,378 NS July 31, 2026 N-PORT
FNX · First Trust Exchange-Traded AlphaDE… 0.23% 13,626 NS July 31, 2026 N-PORT
VBR · VANGUARD INDEX FUNDS 0.23% 701,498 SH Aug. 19, 2026 Daily
DFAS · Dimensional ETF Trust 0.22% 147,648 NS July 31, 2026 N-PORT
IYH · iShares Trust 0.22% 28,670 SH Sept. 11, 2026 Daily
RSP · Invesco Exchange-Traded Fund Trust 0.21% 701,283 SH Oct. 2, 2026 Daily
SMMD · iShares Trust 0.19% 26,152 SH Sept. 11, 2026 Daily
IXJ · iShares Trust 0.17% 25,598 SH Sept. 11, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.17% 23,486 NS July 31, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.16% 148,331 SH Aug. 19, 2026 Daily
REVS · Columbia ETF Trust I 0.15% 2,111 NS July 31, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.15% 3,646 NS July 31, 2026 N-PORT
WSML · iShares Trust 0.14% 6,080 SH Sept. 11, 2026 Daily
IWS · iShares Trust 0.13% 73,404 SH Sept. 11, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.13% 1,102,914 SH Aug. 19, 2026 Daily
CURE · Direxion Shares ETF Trust 0.13% 947 NS July 31, 2026 N-PORT
DFSV · Dimensional ETF Trust 0.12% 42,976 NS July 31, 2026 N-PORT
IEUS · iShares Trust 0.10% 5,579 SH Sept. 11, 2026 Daily
EQAL · Invesco Exchange-Traded Fund Trust … 0.10% 2,769 SH Oct. 2, 2026 Daily
IWR · iShares Trust 0.10% 200,615 SH Sept. 11, 2026 Daily
RECS · Columbia ETF Trust I 0.10% 23,999 NS July 31, 2026 N-PORT
XOEF · iShares Trust 0.07% 61 SH Sept. 11, 2026 Daily
DFUV · Dimensional ETF Trust 0.06% 41,352 NS July 31, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.06% 1,302 NS July 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.05% 106,991 NS July 31, 2026 N-PORT
IVE · iShares Trust 0.04% 79,930 SH Sept. 11, 2026 Daily
IUSV · iShares Trust 0.04% 42,675 SH Sept. 11, 2026 Daily
SCZ · iShares Trust 0.04% 171,786 SH Sept. 11, 2026 Daily
VSS · VANGUARD INTERNATIONAL EQUITY INDEX… 0.04% 174,824 SH Aug. 19, 2026 Daily
VOOV · VANGUARD ADMIRAL FUNDS 0.04% 11,139 SH Aug. 19, 2026 Daily
DCOR · Dimensional ETF Trust 0.04% 5,545 NS July 31, 2026 N-PORT
IWD · iShares Trust 0.04% 108,791 SH Sept. 11, 2026 Daily
CHRI · Global X Funds 0.03% 11 NS July 31, 2026 N-PORT
VONV · VANGUARD SCOTTSDALE FUNDS 0.03% 29,579 SH Aug. 19, 2026 Daily
TOPC · iShares Trust 0.03% 32 SH Sept. 11, 2026 Daily
PRF · Invesco Exchange-Traded Fund Trust 0.03% 9,073 SH Oct. 2, 2026 Daily
DFSU · Dimensional ETF Trust 0.02% 2,431 NS July 31, 2026 N-PORT
XVV · iShares Trust 0.02% 576 SH Sept. 11, 2026 Daily
QVML · Invesco Exchange-Traded Fund Trust … 0.02% 1,258 SH Oct. 2, 2026 Daily
PBP · Invesco Exchange-Traded Fund Trust 0.02% 287 SH Oct. 2, 2026 Daily
EGLE · Global X Funds 0.02% 2 NS July 31, 2026 N-PORT
RWL · Invesco Exchange-Traded Fund Trust … 0.02% 7,022 SH Oct. 2, 2026 Daily
IVV · iShares Trust 0.02% 607,129 SH Sept. 11, 2026 Daily
VOO · VANGUARD INDEX FUNDS 0.02% 1,250,774 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.02% 1,530,468 SH Aug. 19, 2026 Daily
VONE · VANGUARD SCOTTSDALE FUNDS 0.02% 8,168 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.02% 4,112 SH Aug. 19, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.02% 11,106 SH Aug. 19, 2026 Daily
IWV · iShares Trust 0.02% 14,165 SH Sept. 11, 2026 Daily
IWB · iShares Trust 0.02% 33,863 SH Sept. 11, 2026 Daily
XRMI · Global X Funds 0.02% 41 NS July 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.02% 9,979 NS July 31, 2026 N-PORT
XYLD · Global X Funds 0.02% 2,566 NS July 31, 2026 N-PORT
IYY · iShares Trust 0.02% 2,018 SH Sept. 11, 2026 Daily
ITOT · iShares Trust 0.02% 63,582 SH Sept. 11, 2026 Daily
PTLC · Pacer Funds Trust 0.02% 2,492 NS July 31, 2026 N-PORT
PHDG · Invesco Actively Managed Exchange-T… 0.02% 38 SH Oct. 2, 2026 Daily
TILT · FlexShares Trust 0.02% 1,620 NS July 31, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.02% 14,645 NS July 31, 2026 N-PORT
XYLG · Global X Funds 0.02% 45 NS July 31, 2026 N-PORT
SPUU · Direxion Shares ETF Trust 0.02% 182 NS July 31, 2026 N-PORT
QDPL · Pacer Funds Trust 0.02% 1,141 NS July 31, 2026 N-PORT
XTR · Global X Funds 0.01% 3 NS July 31, 2026 N-PORT
HCMT · Direxion Shares ETF Trust 0.01% 332 NS July 31, 2026 N-PORT
SPXL · Direxion Shares ETF Trust 0.01% 3,766 NS July 31, 2026 N-PORT
IEUR · iShares Trust 0.01% 37,473 SH Sept. 11, 2026 Daily
XCLR · Global X Funds 0.01% 2 NS July 31, 2026 N-PORT
OMFL · Invesco Exchange-Traded Self-Indexe… 0.01% 1,973 SH Oct. 2, 2026 Daily
VGK · VANGUARD INTERNATIONAL EQUITY INDEX… 0.01% 110,946 SH Aug. 19, 2026 Daily
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.01% 77,796 SH Aug. 19, 2026 Daily
VEA · VANGUARD TAX-MANAGED FUNDS 0.01% 447,656 SH Aug. 19, 2026 Daily
IDEV · iShares Trust 0.01% 52,174 SH Sept. 11, 2026 Daily
IEFA · iShares Trust 0.00% 272,340 SH Sept. 11, 2026 Daily
NEAR · iShares U.S. ETF Trust 0.00% 140,000 SH Sept. 9, 2026 Daily
DFLV · Dimensional ETF Trust 0.00% 377 NS July 31, 2026 N-PORT
IXUS · iShares Trust 0.00% 22,623 SH Sept. 11, 2026 Daily
VXUS · VANGUARD STAR FUNDS 0.00% 664,961 SH Aug. 19, 2026 Daily
VSGX · VANGUARD WORLD FUND 0.00% 8,805 SH Aug. 19, 2026 Daily
VGHY · VANGUARD FIXED INCOME SECURITIES FU… · · July 15, 2026 Daily
VCRB · VANGUARD MALVERN FUNDS · · July 15, 2026 Daily
VPLS · VANGUARD MALVERN FUNDS · · July 15, 2026 Daily
VSDB · VANGUARD MALVERN FUNDS · · July 15, 2026 Daily
VGMS · VANGUARD MALVERN FUNDS · · July 15, 2026 Daily
ISCB · iShares Trust · 2,146 SH Sept. 11, 2026 Daily
ISCV · iShares Trust · 10,576 SH Sept. 11, 2026 Daily
SMLF · iShares Trust · 18,703 SH Sept. 11, 2026 Daily

CRL Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 23 analysts BUY
Median target $322.00 +11.0%
6 26.1% Strong Buy
11 47.8% Buy
6 26.1% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

15 analysts · 2026-10-02

Mean target $305.00 +5.1%

Now Current price $290.19
Low$145.00 Mean$305.00 High$357.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CRL $10.02B -70.0 -0.85% -3.6% -4.4% ·
WST $19.81B 40.5 6.2% 16.1% 16.2% 35.9%
MEDP $15.93B 36.8 20.0% 17.8% 142.9% ·
RVTY $10.86B 46.7 3.7% 8.5% 3.3% ·
TEM · -41.9 83.4% -19.3% -61.2% ·
TEM · -41.9 83.4% -19.3% -61.2% ·
TXG $2.08B -46.6 5.2% -6.8% -5.5% 69.0%
TECH $11.03B 60.9 -0.38% 15.0% 9.0% 65.8%
RGEN $9.23B 190.5 16.4% 6.6% 2.4% ·
AVTR $7.82B -14.7 -3.4% -8.1% -8.9% 32.6%
BIO · · · · · ·

Latest News Recent headlines mentioning this company

23

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26

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Source: SEC 10-Q filed Aug 5, 2026