FULC Fulcrum Therapeutics, Inc. - Common Stock

NASDAQ · Pharmaceuticals · View on SEC EDGAR ↗
$6.19
Price · May 20, 2026
Fundamentals as of Apr 27, 2026

FULC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$6.19
Market Cap
$753M
P/E (TTM)
-9.6
EPS (TTM)
$-1.18
Revenue (TTM)
$0
Div Yield
ROE
-26.6%
Debt/Equity
52W Range
$6 – $16

FULC Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $0
6-point trend, -100.0%
2020-12-31 2025-12-31
EPS $-1.18
6-point trend, +57.7%
2020-12-31 2025-12-31
Free Cash Flow $-60M
6-point trend, -49.7%
2019-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
FULC
Peer Median
P/E (TTM)
5-point trend, -24.1%
-9.6
24.0
P/B
5-point trend, -37.2%
2.2
2.0
Price / FCF
5-point trend, -109.6%
-12.5

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
FULC
Peer Median
ROA
5-point trend, +59.5%
-23.9%
-22.8%
ROE
5-point trend, +62.4%
-26.6%
-24.5%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
FULC
Peer Median
Current Ratio
5-point trend, +512.7%
27.4
7.8
Quick Ratio
5-point trend, +609.1%
15.1

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
FULC
Peer Median
Revenue YoY
5-point trend, -100.0%
2752.0%
Revenue CAGR 3Y
5-point trend, -100.0%
61.0%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
FULC
Peer Median
EPS (Diluted)
5-point trend, +48.5%
$-1.18

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
FULC
Peer Median

FULC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 16 analysts
  • Strong Buy 5 31.2%
  • Buy 8 50.0%
  • Hold 2 12.5%
  • Sell 1 6.2%
  • Strong Sell 0 0.0%

12-Month Price Target

10 analysts · 2026-05-17
Median target $20.50 +231.2%
Mean target $18.90 +205.3%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.02%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.25 $-0.30 0.05%
Dec. 31, 2025 $-0.31 $-0.32 0.01%
Sept. 30, 2025 $-0.31 $-0.30 -0.01%
June 30, 2025 $-0.28 $-0.30 0.02%
March 31, 2025 $-0.28 $-0.30 0.02%

Peer Comparison Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
FULC $753M -9.6 2752.0% -26.6%
AQST $788M -8.3 -22.6% -188.1% 157.7%
CTNM -5.3 -27.7%
EOLS $432M -8.3 11.6% -17.4% 247.3% 66.3%
AVIR $279M -1.8 -49.5%
SIGA $438M 19.1 -31.8% 24.6% 11.4%
NMRA $312M -1.2 -165.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 12
Annual Income Statement data for FULC
Metric Trend 202520242023202220212020
Revenue 6-point trend, -100.0% $0 $80M $3M $6M $19M $9M
R&D Expense 6-point trend, -5.0% $56M $63M $72M $77M $70M $59M
SG&A Expense 6-point trend, +34.0% $29M $36M $42M $42M $31M $21M
Operating Expenses 6-point trend, +5.4% $85M $102M $113M $119M $100M $80M
Operating Income 6-point trend, -18.4% $-85M $-22M $-111M $-113M $-81M $-72M
Income Tax Flat — no change across 2 periods $0 $0 · · · ·
Net Income 6-point trend, -5.7% $-75M $-10M $-97M $-110M $-81M $-71M
EPS (Basic) 6-point trend, +57.7% $-1.18 $-0.16 $-1.59 $-2.44 $-2.29 $-2.79
EPS (Diluted) 6-point trend, +57.7% $-1.18 $-0.16 $-1.59 $-2.44 $-2.29 $-2.79
Shares (Basic) 6-point trend, +149.9% 63,355 61,984 61,310 44,991 35,361 25,354
Shares (Diluted) 6-point trend, +149.9% 63,355 61,984 61,310 44,991 35,361 25,354
EBITDA 5-point trend, -18.4% $-85M $-22M $-111M $-113M · $-72M
Balance Sheet 21
Annual Balance Sheet data for FULC
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, +246.2% $198M $58M $26M $35M $35M $57M
Prepaid Expense 6-point trend, +27.3% $5M $7M $5M $4M $4M $4M
Other Current Assets 2-point trend, -100.0% · · · · $0 $74.0K
Current Assets 6-point trend, +199.1% $357M $250M $242M $208M $226M $120M
PP&E (Net) 6-point trend, -66.4% $3M $4M $5M $7M $7M $8M
PP&E (Gross) 6-point trend, +27.3% $18M $18M $18M $18M $16M $15M
Accum. Depreciation 6-point trend, +155.8% $16M $14M $13M $11M $8M $6M
Other Non-current Assets 6-point trend, -6.9% $538.0K $10.0K $2M $2M $542.0K $578.0K
Total Assets 6-point trend, +182.7% $366M $261M $258M $227M $235M $130M
Accounts Payable 6-point trend, -61.0% $2M $1M $3M $4M $5M $4M
Current Liabilities 6-point trend, -51.2% $13M $11M $14M $17M $19M $27M
Capital Leases 5-point trend, +4039000.00 $4M $6M $9M $11M $0 ·
Other Non-current Liabilities 5-point trend, +197000.00 $197.0K $197.0K $197.0K $197.0K $0 ·
Total Liabilities 6-point trend, -49.7% $17M $18M $23M $28M $23M $34M
Common Stock 6-point trend, +139.3% $67.0K $54.0K $62.0K $52.0K $41.0K $28.0K
Retained Earnings 6-point trend, -168.2% $-594M $-519M $-510M $-412M $-302M $-222M
Treasury Stock Flat — no change across 2 periods · · · $0 $0 ·
AOCI 6-point trend, +8800.0% $174.0K $130.0K $-136.0K $-797.0K $-397.0K $-2.0K
Stockholders' Equity 6-point trend, +266.7% $349M $243M $235M $199M $212M $95M
Liabilities + Equity 6-point trend, +182.7% $366M $261M $258M $227M $235M $130M
Shares Outstanding 6-point trend, +138.3% 66,578,891 53,968,303 61,915,367 52,099,211 40,626,224 27,941,566
Cash Flow 10
Annual Cash Flow data for FULC
Metric Trend 202520242023202220212020
Stock-based Comp 6-point trend, +69.6% $12M $15M $15M $13M $11M $7M
Restructuring 3-point trend, +0.0% $400.0K $2M · $400.0K · ·
Operating Cash Flow 6-point trend, -11.9% $-60M $-2M $-91M $-97M $-78M $-54M
CapEx 6-point trend, -76.6% $314.0K $278.0K $508.0K $2M $2M $1M
Investing Cash Flow 6-point trend, +153.8% $31M $32M $-37M $12M $-130M $-57M
Stock Issued 6-point trend, +191.6% $4M $3M $777.0K $4M $4M $1M
Net Stock Activity 5-point trend, +191.6% $4M $3M $777.0K $4M · $1M
Financing Cash Flow 6-point trend, +137.1% $169M $3M $118M $84M $187M $71M
Net Change in Cash 6-point trend, +451.3% $139M $33M $-10M $-314.0K $-22M $-40M
Free Cash Flow 5-point trend, -9.8% $-60M $-2M $-91M $-99M · $-55M
Profitability 5
Annual Profitability data for FULC
Metric Trend 202520242023202220212020
Operating Margin 4-point trend, +96.6% · -27.4% -3945.2% -1774.8% · -811.6%
Net Margin 4-point trend, +98.5% · -12.2% -3470.0% -1732.4% · -802.7%
EBITDA Margin 4-point trend, +96.6% · -27.4% -3945.2% -1774.8% · -811.6%
ROA 5-point trend, +59.5% -23.9% -3.8% -40.2% -47.6% · -59.0%
ROE 5-point trend, +62.4% -26.6% -3.9% -39.7% -52.3% · -70.8%
Liquidity & Solvency 2
Annual Liquidity & Solvency data for FULC
Metric Trend 202520242023202220212020
Current Ratio 5-point trend, +512.7% 27.4 22.6 17.7 12.4 · 4.5
Quick Ratio 5-point trend, +609.1% 15.1 5.3 1.9 2.1 · 2.1
Efficiency 1
Annual Efficiency data for FULC
Metric Trend 202520242023202220212020
Asset Turnover 5-point trend, -100.0% 0.0 0.3 0.0 0.0 · 0.1
Per Share 5
Annual Per Share data for FULC
Metric Trend 202520242023202220212020
Book Value / Share 5-point trend, +53.9% $5.24 $4.50 $3.80 $3.82 · $3.41
Revenue / Share 4-point trend, -100.0% $0.00 $1290.66 $45.75 $140.96 · ·
Cash Flow / Share 4-point trend, +56.0% $-948.07 $-35.78 $-1483.69 $-2157.10 · ·
Cash / Share 5-point trend, +45.3% $2.97 $1.08 $0.41 $0.67 · $2.04
EPS (TTM) 6-point trend, +57.7% $-1.18 $-0.16 $-1.59 $-2.44 $-2.29 $-2.79
Growth Rates 2
Annual Growth Rates data for FULC
Metric Trend 202520242023202220212020
Revenue YoY 4-point trend, +2248.4% · 2752.0% -55.8% -66.9% 117.2% ·
Revenue CAGR 3Y 2-point trend, +292.2% · 61.0% -31.8% · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for FULC
Metric Trend 202520242023202220212020
Revenue TTM 6-point trend, -100.0% $0 $80M $3M $6M $19M $9M
Net Income TTM 6-point trend, -5.7% $-75M $-10M $-97M $-110M $-81M $-71M
Market Cap 5-point trend, +130.1% $753M $254M $418M $379M · $327M
P/E 6-point trend, -128.4% -9.6 -29.4 -4.2 -3.0 -7.7 -4.2
P/S 4-point trend, -91.5% · 3.2 149.0 59.8 · 37.1
P/B 5-point trend, -37.2% 2.2 1.0 1.8 1.9 · 3.4
P / Tangible Book 6-point trend, -37.2% 2.2 1.0 1.8 1.9 3.4 3.4
P / Cash Flow 5-point trend, -105.6% -12.5 -114.4 -4.6 -3.9 · -6.1
P / FCF 5-point trend, -109.6% -12.5 -101.6 -4.6 -3.8 · -5.9
Earnings Yield 6-point trend, +56.2% -10.4% -3.4% -23.6% -33.5% -13.0% -23.8%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $0$80M$3M$6M$19M
Operating Margin % -27.4%-3945.2%-1774.8%
Net Income $-75M$-10M$-97M$-110M$-81M
Diluted EPS $-1.18$-0.16$-1.59$-2.44$-2.29
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 27.422.617.712.4
Quick Ratio 15.15.31.92.1
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-60M$-2M$-91M$-99M

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