MREO Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $0.38
Market Cap (MRQ) $303M
P/E -7.6
EPS $-0.05
Revenue $500.0K
ROE -88.1%
52W Range $0–$2

MREO Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
range
bars

Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$500.0K
2022-12-31 → 2025-12-31
EPS$-0.05
2022-12-31 → 2025-12-31
Free Cash Flow$-31M
2023-12-31 → 2025-12-31
Net margin-8375.6%
2023-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend MREO 5Y avg Peer Median Verdict
P/E -7.65Y avg ≈-41.5 ≈-41.5 · ·
P/S 606.2 · · ·
P/B (MRQ) 10.65Y avg ≈28.2 ≈28.2 · ·
Price / FCF (TTM) -12.0 · · ·
Price / Cash Flow (TTM) -12.05Y avg ≈-56.7 ≈-56.7 · ·
Price / Tangible Book (MRQ) 10.75Y avg ≈28.7 ≈28.7 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -130.7%
Next Report Nov 09, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 10, 2026 $-0.01 $-0.01 —
March 31, 2026 May 11, 2026 $-0.01 $-0.01 2.0%
Dec. 31, 2025 $-0.01 $-0.01 23.7%
Sept. 30, 2025 $-0.01 $-0.02 59.7%
June 30, 2025 $-0.10 $-0.02 -498.8%
March 31, 2025 $-0.10 $-0.01 —
Dec. 31, 2024 $-0.05 $-0.01 -240.1%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 15
Metric Trend 2025202420232022
Revenue $500.0K$0$10M$0
R&D Expense $18M$21M$17M$29M
SG&A Expense $23M$26M$18M$26M
Operating Income $-40M$-47M$-28M$-54M
Interest Expense $255.0K$1M$3M$4M
Interest Income $104.0K$0$2M$840.0K
Other Non-op $300.0K$0$-10.0K$1M
Pretax Income $-42M$-43M$-30M$-43M
Income Tax $0$0$-532.0K$-718.0K
Net Income $-42M$-43M$-29M$-42M
EPS (Basic) $-0.05$-0.06$-0.04$-0.07
EPS (Diluted) $-0.05$-0.06$-0.04$-0.07
Shares (Basic) 797,119,632739,624,264659,453,921603,196,403
Shares (Diluted) 797,119,632739,624,264659,453,921603,196,403
EBITDA $-40M$-47M$-28M·
Balance Sheet 22
Metric Trend 2025202420232022
Cash & Equivalents $41M$70M$57M$68M
Prepaid Expense $3M$2M$5M$5M
Current Assets $45M$75M$64M$75M
PP&E (Net) $137.0K$257.0K$405.0K$551.0K
PP&E (Gross) $1M$1M$1M$1M
Accum. Depreciation $1M$949.0K$800.0K$736.0K
Intangibles $516.0K$643.0K$1M$0
Total Assets $46M$76M$66M$77M
Accounts Payable $1M$2M$2M$3M
Accrued Liabilities $2M$4M$5M$5M
Current Liabilities $4M$14M$9M$24M
Capital Leases $0$187.0K$906.0K$1M
Other Non-current Liabilities $661.0K$565.0K$764.0K$0
Total Liabilities $5M$15M$16M$26M
Common Stock $3M$3M$3M$2M
Paid-in Capital $550M$540M$486M$477M
Retained Earnings $-501M$-463M$-420M$-405M
Treasury Stock ·$0$1M$1M
AOCI $-11M$-19M$-17M$-22M
Stockholders' Equity $41M$61M$51M$51M
Liabilities + Equity $46M$76M$66M$77M
Shares Outstanding 795,658,504775,728,034701,217,089624,928,519
Cash Flow 13
Metric Trend 2025202420232022
Stock-based Comp $8M$7M$5M$5M
Deferred Tax ·$0$0$0
Amort. of Intangibles $465.0K$438.0K$395.0K$0
Operating Cash Flow $-31M$-33M$-21M$-49M
CapEx $20.0K$0$0$13.0K
Investing Cash Flow $-20.0K$-699.0K$-419.0K$2M
Stock Issued $39.0K$47M$12M$0
Net Stock Activity $39.0K$47M$12M·
Financing Cash Flow $327.0K$46M$8M$200.0K
Net Change in Cash ·$12M$-11M·
Taxes Paid ·$0$-1M$2M
Free Cash Flow $-31M·$-21M·
Levered FCF $-31M·$-24M·
Profitability 7
Metric Trend 2025202420232022
Operating Margin -8021.4%·-284.2%·
Net Margin -8375.6%·-294.7%·
Pretax Margin -8375.6%·-300.0%·
EBITDA Margin -8021.4%·-284.2%·
ROA -68.5%-60.5%-40.9%·
ROE -88.1%747.9%-56.0%·
ROIC -98.0%-77.7%-55.2%·
Liquidity & Solvency 3
Metric Trend 2025202420232022
Current Ratio 10.55.46.7·
Quick Ratio 9.55.06.1·
Interest Coverage -157.3-34.6-9.9·
Efficiency 1
Metric Trend 2025202420232022
Asset Turnover 0.00.00.1·
Per Share 5
Metric Trend 2025202420232022
Book Value / Share $0.05$0.08$0.07·
Revenue / Share $0.00$0.00$0.02·
Cash Flow / Share $-0.04$-0.04$-0.03·
Cash / Share $0.05$0.09$0.08·
EPS (TTM) $-0.05$-0.06$-0.04·
Valuation (TTM) 10
Metric Trend 2025202420232022
Revenue TTM $500.0K$0$10M·
Net Income TTM $-42M$-43M$-29M·
Market Cap $332M$2.72B$1.62B·
P/E -8.3-58.3-57.8·
P/S 663.6·162.0·
P/B 8.144.532.1·
P / Tangible Book 8.245.032.8·
P / Cash Flow -10.7-82.7-76.7·
P / FCF -10.7·-76.7·
Earnings Yield -12.0%-1.7%-1.7%·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-31
Revenue $500.0K $0 $10M $0
Operating Margin % -8021.4% · -284.2% ·
Net Income $-42M $-43M $-29M $-42M
Diluted EPS $-0.05 $-0.06 $-0.04 $-0.07

Institutional owners (13F) 66 filers · $18.3M total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 66
Value held $18.3M
New positions 13
Exited positions 17
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
13 (-2 vs prior Q) 17 (-6 vs prior Q) 15 (-2 vs prior Q) 15 (-5 vs prior Q) -18.9M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Rubric Capital Management LP $4,863,144 15,307,347 26.50% Shares
683 Capital Management, LLC $3,741,825 11,777,856 20.39% Shares
BANK OF AMERICA CORP /DE/ $2,597,904 8,195,281 14.16% Shares
Defilade Capital Management, L.P. $2,401,417 7,558,756 13.09% Shares
Newtyn Management, LLC $953,100 3,000,000 5.19% Shares
Tejara Capital Ltd $647,320 2,037,520 3.53% Shares
UBS Group AG $460,346 1,447,627 2.51% Shares
TWO SIGMA INVESTMENTS, LP $419,123 1,319,241 2.28% Shares
EcoR1 Capital, LLC $317,700 1,000,000 1.73% Shares
JANE STREET GROUP, LLC $246,200 774,944 1.34% Shares
Ishara Investments LP $244,232 768,750 1.33% Shares
Wealthspire Advisors, LLC $243,041 765,000 1.32% Shares
CITADEL ADVISORS LLC $160,407 504,900 0.87% Call option
CITADEL ADVISORS LLC $141,109 444,158 0.77% Shares
TWO SIGMA ADVISERS, LP $104,967 251,900 0.57% Shares
Rangeley Capital, LLC $104,587 329,200 0.57% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $67,756 213,270 0.37% Shares
MARSHALL WACE, LLP $57,563 179,884 0.31% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $55,520 173,500 0.30% Call option
XTX Topco Ltd $55,433 174,481 0.30% Shares
GROUP ONE TRADING LLC $53,220 167,515 0.29% Shares
STATE STREET CORP $42,817 134,772 0.23% Shares
Sheets Smith Investment Management $34,793 16,890 0.19% Shares
NOMURA HOLDINGS INC $33,155 104,361 0.18% Shares
James J. Burns & Company, LLC $30,309 95,400 0.17% Shares
Quarry LP $29,784 93,750 0.16% Shares
GOLDMAN SACHS GROUP INC $27,062 85,180 0.15% Shares
JMN Financial LLC $24,383 76,748 0.13% Shares
BlackRock, Inc. $22,137 69,678 0.12% Shares
JPMORGAN CHASE & CO $19,421 58,531 0.11% Shares
RENAISSANCE TECHNOLOGIES LLC $16,552 52,100 0.09% Shares
CITADEL ADVISORS LLC $16,203 51,000 0.09% Put option
SUSQUEHANNA INTERNATIONAL GROUP, LLP $14,720 46,000 0.08% Put option
Significant Wealth Partners LLC $10,382 32,677 0.06% Shares
Clear Harbor Asset Management, LLC $10,083 32,000 0.05% Shares
RHUMBLINE ADVISERS $8,511 26,784 0.05% Shares
Centiva Capital, LP $7,943 25,000 0.04% Shares
Engineers Gate Manager LP $7,610 23,953 0.04% Shares
SIMPLEX TRADING, LLC $5,972 18,780 0.03% Shares
NFSG Corp $5,957 18,750 0.03% Shares
OneDigital Investment Advisors LLC $5,814 18,300 0.03% Shares
MORGAN STANLEY $5,317 16,731 0.03% Shares
IHT Wealth Management, LLC $4,766 15,000 0.03% Shares
TWO SIGMA SECURITIES, LLC $4,098 12,900 0.02% Shares
J. Safra Sarasin Holding AG $4,081 12,841 0.02% Shares
MML INVESTORS SERVICES, LLC $3,876 12,200 0.02% Shares
JANE STREET GROUP, LLC $3,749 11,800 0.02% Call option
World Investment Advisors $3,300 10,000 0.02% Shares
Astoria Portfolio Advisors LLC. $3,177 10,000 0.02% Shares
GAMMA Investing LLC $2,957 9,308 0.02% Shares

Show all 66 institutional owners →

Activists & 5%+ owners 2 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Rubric Capital Management LP, David Rosen ×16 filings June 17, 2024 · Initial filing · SEC
Mereo BioPharma Group plc, Dr. Denise Scots-Knight Dec. 17, 2018 · Initial filing M&A / sale SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 13 insiders · 5 officers · 9 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Denise Scots-Knight Chief Executive Officer Feb. 1, 2026 A 808,921 0 0 $0
Chrisitne Ann Fox Chief Financial Officer Feb. 1, 2026 A 89,285 0 0 $0
Alexandra Hughes-Wilson Chief Patient Access and Commercial Planning Feb. 1, 2026 A 50,475 0 0 $0
Charles Sermon General Counsel Feb. 1, 2026 A 219,061 0 0 $0
John A. Lewicki Chief Scientific Officer Feb. 1, 2026 A 78,630 0 0 $0
Anders Ekblom Director Feb. 26, 2026 A · 0 0 $0
Daniel Shames Director Feb. 26, 2026 A · 0 0 $0
Jeremy Bender Director Feb. 26, 2026 A 12,550 0 0 $0
Pierre Jacquet Director Feb. 26, 2026 A · 0 0 $0
Annalisa Jenkins Director Feb. 26, 2026 A · 0 0 $0
Marc J Yoskowitz Director Feb. 26, 2026 A · 0 0 $0
Deepika Pakianathan Director Feb. 26, 2026 A 0 0 0 $0
Michael S Wyzga Director Feb. 26, 2026 A 25,050 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

MREO Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 14 analysts BUY
Median target $1.93 +409.0%
5 35.7% Strong Buy
5 35.7% Buy
3 21.4% Hold
1 7.1% Sell
0 0.0% Strong Sell

12-Month Price Target

5 analysts · 2026-10-01

Mean target $1.95 +414.5%

← Below all targets Current price $0.38
Low$0.98 Mean$1.95 High$2.96

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
MREO $332M -8.3 · -8375.6% -88.1% ·
OKYO · -6.7 · · -263.8% ·
ROIV $19.95B -51.3 -71.6% -3629.2% -6.5% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

Pick the metrics that matter to you — click the + next to any row in Full Fundamentals above.

Your selection is saved and follows you across all tickers.

Source: SEC 10-Q filed Aug 11, 2026