NXTC NextCure, Inc. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ 10-K/10-Q Aug 6, 2026
$4.98
· of 52w range
· above low
· to high
$1.5552w low
$15.7452w high
Market Cap (MRQ)
$20M
P/E
-0.3
EPS
$-19.65
your badges
52W Range
$2–$16
Analyst Rating
BUY
Price Target
$20
P/E
-0.3
ROE
-172.9%
Net Profit Margin
·
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NXTC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$4.98
Market Cap (MRQ)
$20M
P/E
-0.3
EPS
$-19.65
ROE
-172.9%
52W Range
$2–$16
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Stock splits
| Ex-date | Split | Type |
|---|---|---|
| July 14, 2025 | 1-for-12 | Reverse |
10-Year Performance Revenue, net income, margins and EPS trends
Revenue·2019-12-31 → 2020-12-31
EPS$-19.652020-12-31 → 2025-12-31
Free Cash Flow·2019-12-31 → 2024-12-31
Net margin·2019-12-31 → 2019-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | NXTC | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -0.35Y avg ≈-8.4 | ≈-8.4 | · | · | |
| P/S | 0.75Y avg ≈23.6 | ≈23.6 | 20.1 | Undervalued | |
| P/B (MRQ) | 1.75Y avg ≈4.0 | ≈4.0 | 0.7 | Undervalued | |
| Price / Cash Flow | -0.45Y avg ≈-11.6 | ≈-11.6 | · | · | |
| Price / Tangible Book | 0.55Y avg ≈4.0 | ≈4.0 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | NXTC | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -85.2%5Y avg ≈-47.8% | ≈-47.8% | -51.5% | Weak | |
| ROE | -172.9%5Y avg ≈-75.1% | ≈-75.1% | -107.6% | Weak |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | NXTC | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 3.55Y avg ≈16.1 | ≈16.1 | 3.1 | In line | |
| Quick Ratio | 2.55Y avg ≈2.4 | ≈2.4 | 2.5 | In line |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-12.8%
Next Report
Nov 03, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 5, 2026 | $-2.80 | $-1.97 | -42.1% |
| March 31, 2026 | $-1.87 | $-2.15 | 12.8% | |
| Dec. 31, 2025 | $-0.81 | $-2.46 | 67.1% | |
| Sept. 30, 2025 | $-3.22 | $-4.06 | 20.7% | |
| June 30, 2025 | $-11.29 | $-4.71 | -139.8% | |
| March 31, 2025 | $-4.68 | $-4.90 | 4.4% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | $22M | $6M | |
| R&D Expense | $45M | $41M | $48M | $54M | $50M | $47M | $34M | |
| SG&A Expense | $13M | $16M | $20M | $22M | $21M | $17M | $10M | |
| Operating Expenses | $58M | $60M | $68M | $76M | $71M | $64M | $44M | |
| Operating Income | $-58M | $-60M | $-68M | $-76M | $-71M | $-41M | $-37M | |
| Interest Expense | · | · | · | · | · | $183.0K | $209.0K | |
| Other Non-op | $2M | $4M | $5M | $1M | $1M | $5M | $4M | |
| Income Tax | $0 | · | · | · | · | · | · | |
| Net Income | $-56M | $-56M | $-63M | $-75M | $-69M | $-37M | $-34M | |
| EPS (Basic) | $-19.65 | $-23.88 | $-2.25 | $-2.69 | $-2.51 | $-1.33 | · | |
| EPS (Diluted) | $-19.65 | $-23.88 | $-2.25 | $-2.69 | $-2.51 | $-1.33 | · | |
| Shares (Basic) | 2,842,448 | 2,330,386 | 27,836,584 | 27,744,209 | 27,615,977 | 27,532,177 | · | |
| Shares (Diluted) | 2,842,448 | 2,330,386 | 27,836,584 | 27,744,209 | 27,615,977 | 27,532,177 | · | |
| EBITDA | $-55M | $-57M | $-64M | $-72M | $-66M | · | $-35M |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $26M | $28M | $13M | $27M | $12M | $33M | $34M | |
| Prepaid Expense | $2M | $3M | $4M | $4M | $8M | $3M | $4M | |
| Current Assets | $44M | $72M | $113M | $164M | $228M | $288M | $340M | |
| PP&E (Net) | $3M | $5M | $9M | $12M | $14M | $16M | $12M | |
| PP&E (Gross) | $29M | $29M | $29M | $29M | $27M | $24M | $17M | |
| Accum. Depreciation | $25M | $23M | $20M | $17M | $13M | $9M | $5M | |
| Other Non-current Assets | $546.0K | $332.0K | $2M | $3M | $577.0K | $3M | $4M | |
| Total Assets | $50M | $81M | $128M | $184M | $242M | $307M | $356M | |
| Accounts Payable | $2M | $5M | $2M | $4M | $2M | $4M | $2M | |
| Accrued Liabilities | · | · | · | · | $4M | $5M | $5M | |
| Current Liabilities | $11M | $10M | $7M | $9M | $7M | $10M | $15M | |
| Capital Leases | $4M | $5M | $6M | $7M | · | · | · | |
| Other Non-current Liabilities | $526.0K | $661.0K | $785.0K | $899.0K | $2M | · | · | |
| Total Liabilities | $15M | $15M | $14M | $17M | $9M | $13M | $35M | |
| Long-term Debt | · | · | · | $0 | $0 | $4M | $5M | |
| Total Debt | · | · | · | · | · | · | $5M | |
| Common Stock | $4.0K | $2.0K | $28.0K | $28.0K | $28.0K | $28.0K | $27.0K | |
| Paid-in Capital | $471M | $446M | $439M | $431M | $421M | $411M | $403M | |
| Retained Earnings | $-436M | $-380M | $-324M | $-262M | $-187M | $-118M | $-81M | |
| AOCI | $21.0K | $4.0K | $-222.0K | $-1M | $-663.0K | $779.0K | $-38.0K | |
| Stockholders' Equity | $35M | $65M | $114M | $168M | $233M | $294M | $321M | |
| Liabilities + Equity | $50M | $81M | $128M | $184M | $242M | $307M | $356M | |
| Shares Outstanding | 3,505,621 | 2,333,896 | 2,325,259 | 27,774,536 | 27,680,997 | 27,568,802 | 27,499,260 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $3M | $4M | $4M | $4M | $3M | $3M | |
| Stock-based Comp | $3M | $6M | $8M | $10M | $10M | $8M | $2M | |
| Other Non-cash | $1M | $6M | $-2M | $7M | $-2M | · | $-6M | |
| Operating Cash Flow | $-50M | $-41M | $-53M | $-54M | $-57M | $-45M | $-36M | |
| CapEx | · | $474.0K | $820.0K | $2M | $2M | $7M | $3M | |
| Investing Cash Flow | $26M | $55M | $39M | $68M | $37M | $44M | $-304M | |
| Stock Issued | · | $39.0K | $5.0K | · | · | $112.0K | $119.0K | |
| Net Stock Activity | · | $39.0K | · | · | · | · | $119.0K | |
| Financing Cash Flow | $22M | $144.0K | $154.0K | $200.0K | $-3M | $-1M | $243M | |
| Net Change in Cash | $-2M | $15M | $-14M | $14M | $-24M | $-3M | $-97M | |
| Free Cash Flow | · | $-41M | $-54M | $-56M | $-60M | · | $-39M |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | -590.5% | |
| Net Margin | · | · | · | · | · | · | -531.5% | |
| EBITDA Margin | · | · | · | · | · | · | -548.0% | |
| ROA | -85.2% | -53.3% | -40.2% | -35.0% | -25.3% | · | -13.4% | |
| ROE | -172.9% | -78.9% | -52.1% | -42.8% | -28.8% | · | -13.7% |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 4.1 | 7.5 | 16.4 | 18.0 | 34.5 | · | 22.6 | |
| Quick Ratio | 2.5 | 2.9 | 1.9 | 2.9 | 1.9 | · | 2.3 | |
| Debt / Equity | · | · | · | · | · | · | 0.0 | |
| LT Debt / Equity | · | · | · | · | · | · | 0.0 | |
| Interest Coverage | · | · | · | · | · | · | -179.3 |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | 0.0 |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $9.97 | $2.34 | $4.10 | $6.03 | $8.43 | · | $11.69 | |
| Cash Flow / Share | $-17.45 | $-1.46 | $-1.90 | $-1.94 | $-2.07 | · | · | |
| Cash / Share | $7.41 | $0.99 | $0.47 | $0.96 | $0.45 | · | $1.24 | |
| Dividend / Share | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | |
| EPS (TTM) | $-19.65 | $-23.88 | $-2.25 | $-2.69 | $-2.51 | $-1.33 | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $27M | $27M | $27M | $27M | $27M | $22M | $6M | |
| Net Income TTM | $-56M | $-56M | $-63M | $-75M | $-69M | $-37M | $-34M | |
| Market Cap | $50M | $259M | $382M | $470M | $1.99B | · | $18.59B | |
| Enterprise Value | · | · | · | · | · | · | $18.56B | |
| P/E | -0.7 | -0.4 | -6.1 | -6.3 | -28.7 | -98.3 | · | |
| P/S | 1.9 | 9.7 | 14.3 | 17.6 | 74.6 | · | 2928.7 | |
| P/B | 1.4 | 4.0 | 3.3 | 2.8 | 8.5 | · | 57.8 | |
| P / Tangible Book | 1.4 | 4.0 | 3.3 | 2.8 | 8.5 | 12.3 | · | |
| P / Cash Flow | -1.0 | -6.4 | -7.2 | -8.7 | -34.8 | · | -521.8 | |
| P / FCF | · | -6.3 | -7.1 | -8.4 | -33.4 | · | -476.7 | |
| EV / EBITDA | · | · | · | · | · | · | -533.6 | |
| EV / FCF | · | · | · | · | · | · | -476.0 | |
| EV / Revenue | · | · | · | · | · | · | 2924.1 | |
| Earnings Yield | -138.5% | -258.1% | -16.4% | -15.9% | -3.5% | -1.0% | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $7M | $7M | $7M | $6M | $24M | $8M | $9M | $9M | $12M | $11M | $12M | $11M | $13M | $12M | $13M | $14M | |
| SG&A Expense | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $6M | $5M | $5M | $6M | |
| Operating Expenses | $15M | $10M | $10M | $9M | $27M | $12M | $12M | $12M | $16M | $18M | $16M | $16M | $19M | $17M | $18M | $19M | |
| Operating Income | $-15M | $-10M | $-10M | $-9M | $-27M | $-12M | $-12M | $-12M | $-16M | $-18M | $-16M | $-16M | $-19M | $-17M | $-18M | $-19M | |
| Other Non-op | $202.0K | $309.0K | $321.0K | $321.0K | $484.0K | $646.0K | $852.0K | $955.0K | $1M | $1M | $1M | $1M | $1M | $975.0K | $471.0K | $328.0K | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | · | $0 | $0 | $0 | · | $0 | $0 | $0 | · | $0 | |
| Net Income | $-15M | $-10M | $-9M | $-9M | $-27M | $-11M | $-12M | $-12M | $-15M | $-17M | $-14M | $-14M | $-18M | $-16M | $-17M | $-19M | |
| EPS (Basic) | $-2.80 | $-1.87 | $-4.75 | $-3.22 | $-11.29 | $-4.70 | $-11.71 | $-4.95 | $-6.61 | $-0.61 | $-0.52 | $-0.51 | $-0.64 | $-0.58 | $-0.62 | $-0.68 | |
| EPS (Diluted) | $-2.80 | $-1.87 | $-4.75 | $-3.22 | $-11.29 | $-4.70 | $-11.71 | $-4.95 | $-6.61 | $-0.61 | $-0.52 | $-0.51 | $-0.64 | $-0.58 | $-0.62 | $-0.68 | |
| Shares (Basic) | 5,309,724 | 5,239,236 | · | 2,676,116 | 2,374,729 | 2,333,890 | · | 2,331,320 | 2,331,062 | 27,903,040 | · | 27,839,968 | 27,828,741 | 27,774,536 | · | 27,748,844 | |
| Shares (Diluted) | 5,309,724 | 5,239,236 | · | 2,676,116 | 2,374,729 | 2,333,890 | · | 2,331,320 | 2,331,062 | 27,903,040 | · | 27,839,968 | 27,828,741 | 27,774,536 | · | 27,748,844 | |
| EBITDA | $-15M | $-10M | · | $-9M | $-27M | $-12M | · | $-12M | $-16M | $-18M | · | $-16M | $-19M | $-17M | · | $-19M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $15M | $15M | $26M | $7M | $5M | $22M | $28M | $28M | $21M | $18M | $13M | $20M | $22M | $30M | $27M | $31M | |
| Prepaid Expense | $2M | $2M | $2M | $4M | $5M | $3M | $3M | $3M | $4M | $7M | $4M | $4M | $5M | $3M | $4M | $6M | |
| Current Assets | $22M | $32M | $44M | $33M | $40M | $59M | $72M | $79M | $90M | $103M | $113M | $123M | $135M | $149M | $164M | $175M | |
| PP&E (Net) | $283.0K | $3M | $3M | $4M | $4M | $5M | $5M | $6M | $7M | $7M | $9M | $10M | $11M | $11M | $12M | $12M | |
| PP&E (Gross) | · | · | $29M | · | · | · | $29M | · | · | · | $29M | · | · | · | $29M | · | |
| Accum. Depreciation | · | · | $25M | · | · | · | $23M | · | · | · | $20M | · | · | · | $17M | · | |
| Other Non-current Assets | $82.0K | $847.0K | $546.0K | $550.0K | $555.0K | $328.0K | $332.0K | $2M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $2M | |
| Total Assets | $23M | $38M | $50M | $40M | $48M | $67M | $81M | $90M | $103M | $115M | $128M | $140M | $153M | $168M | $184M | $190M | |
| Accounts Payable | $3M | $3M | $2M | $2M | $3M | $3M | $5M | $4M | $5M | $4M | $2M | $3M | $3M | $2M | $4M | $2M | |
| Accrued Liabilities | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $4M | |
| Current Liabilities | $6M | $7M | $11M | $11M | $11M | $6M | $10M | $9M | $11M | $10M | $7M | $7M | $8M | $6M | $9M | $6M | |
| Capital Leases | $4M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | $6M | $6M | $6M | $6M | $6M | $6M | $7M | · | |
| Other Non-current Liabilities | $455.0K | $491.0K | $526.0K | $561.0K | $596.0K | $629.0K | $661.0K | $693.0K | $725.0K | $755.0K | $785.0K | $815.0K | $843.0K | $872.0K | $899.0K | · | |
| Total Liabilities | $10M | $11M | $15M | $16M | $16M | $11M | $15M | $15M | $17M | $16M | $14M | $13M | $15M | $14M | $17M | $8M | |
| Common Stock | $4.0K | $4.0K | $4.0K | $3.0K | $2.0K | $28.0K | $2.0K | $28.0K | $28.0K | $28.0K | $28.0K | $28.0K | $28.0K | $28.0K | $28.0K | $28.0K | |
| Paid-in Capital | $473M | $472M | $471M | $450M | $448M | $447M | $446M | $444M | $442M | $441M | $439M | $437M | $435M | $433M | $431M | $428M | |
| Retained Earnings | $-461M | $-446M | $-436M | $-427M | $-418M | $-391M | $-380M | $-369M | $-357M | $-342M | $-324M | $-310M | $-296M | $-278M | $-262M | $-244M | |
| AOCI | $-3.0K | $-2.0K | $21.0K | $17.0K | $-7.0K | · | $4.0K | $76.0K | $-86.0K | $-182.0K | $-222.0K | $-603.0K | $-925.0K | $-803.0K | $-1M | $-2M | |
| Stockholders' Equity | $12M | $27M | $35M | $24M | $30M | $56M | $65M | $76M | $85M | $99M | $114M | $126M | $138M | $154M | $168M | $182M | |
| Liabilities + Equity | $23M | $38M | $50M | $40M | $48M | $67M | $81M | $90M | $103M | $115M | $128M | $140M | $153M | $168M | $184M | $190M | |
| Shares Outstanding | 4,068,951 | 3,607,555 | 3,505,621 | 2,676,110 | 2,337,516 | 28,006,684 | 2,333,896 | 27,975,840 | 27,975,840 | 27,903,627 | 27,903,027 | 27,839,968 | 27,839,968 | 27,774,536 | 27,774,536 | 27,748,844 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $304.0K | $344.0K | $435.0K | $600.0K | $588.0K | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Operating Cash Flow | $-10M | $-13M | $-8M | $-6M | $-23M | $-13M | $-7M | $-11M | $-10M | $-13M | $-11M | $-13M | $-15M | $-15M | $-9M | $-15M | |
| CapEx | · | · | · | · | · | · | $-34.0K | $170.0K | $301.0K | $37.0K | $13.0K | $279.0K | $280.0K | $248.0K | $865.0K | $532.0K | |
| Investing Cash Flow | $10M | $1M | $6M | $9M | $4M | $7M | $7M | $18M | $12M | $18M | $4M | $10M | $7M | $18M | $4M | $18M | |
| Stock Issued | $0 | $1M | · | · | · | · | · | $0 | · | · | · | · | · | · | · | · | |
| Net Stock Activity | · | $1M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $22.0K | $1M | $20M | $0 | · | · | $37.0K | $0 | $106.0K | $1.0K | $71.0K | $0 | · | · | $61.0K | $0 | |
| Net Change in Cash | $93.0K | $-11M | $19M | $2M | $-17M | $-6M | $26.0K | $7M | $2M | $5M | $-6M | $-2M | $-8M | $3M | $-4M | $3M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | $-13M | · | · | · | $-15M | · | · |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -42.4% | -18.6% | · | -13.3% | -35.7% | -12.0% | · | -10.0% | -12.0% | -12.1% | · | -8.7% | -9.9% | -8.2% | · | -8.5% | |
| ROE | -71.3% | -23.7% | · | -17.4% | -46.6% | -14.2% | · | -11.4% | -13.8% | -13.5% | · | -9.3% | -10.6% | -8.7% | · | -8.8% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.5 | 4.6 | · | 3.0 | 3.7 | 10.3 | · | 9.1 | 8.3 | 10.7 | · | 18.7 | 17.3 | 23.8 | · | 29.8 | |
| Quick Ratio | 2.4 | 2.2 | · | 0.7 | 0.5 | 3.8 | · | 3.2 | 1.9 | 1.9 | · | 3.0 | 2.8 | 4.8 | · | 5.3 |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $2.99 | $7.41 | · | $8.84 | $12.68 | $1.99 | · | $2.70 | $3.05 | $3.55 | · | $4.54 | $4.97 | $5.55 | · | $6.54 | |
| Cash Flow / Share | · | $-2.55 | · | · | · | $-0.46 | · | · | · | $-0.45 | · | · | · | $-0.53 | · | · | |
| Cash / Share | $3.75 | $4.20 | · | $2.74 | $2.09 | $0.78 | · | $0.99 | $0.75 | $0.66 | · | $0.70 | $0.79 | $1.08 | · | $1.12 | |
| EPS (TTM) | $-12.64 | $-21.13 | · | $-30.92 | $-32.65 | $-27.97 | · | $-12.69 | $-8.25 | $-2.28 | · | $-2.35 | $-2.52 | $-2.53 | · | $-2.68 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $22M | $22M | · | $22M | $22M | $22M | · | $22M | $22M | $22M | · | $22M | $22M | $22M | · | $22M | |
| Net Income TTM | $-43M | $-55M | · | $-58M | $-61M | $-50M | · | $-59M | $-61M | $-64M | · | $-66M | $-70M | $-70M | · | $-74M | |
| Market Cap | $7M | $39M | · | $16M | $13M | $161M | · | $460M | $534M | $747M | · | $431M | $601M | $493M | · | $916M | |
| P/E | -0.1 | -0.5 | · | -0.2 | -0.2 | -0.2 | · | -1.3 | -2.3 | -11.7 | · | -6.6 | -8.6 | -7.0 | · | -12.3 | |
| P/S | 0.3 | 1.7 | · | 0.7 | 0.6 | 7.2 | · | 20.6 | 23.9 | 33.4 | · | 19.3 | 26.9 | 22.0 | · | 40.9 | |
| P/B | 0.5 | 1.4 | · | 0.7 | 0.4 | 2.9 | · | 6.1 | 6.2 | 7.5 | · | 3.4 | 4.3 | 3.2 | · | 5.0 | |
| P / Tangible Book | 0.5 | 1.4 | · | 0.7 | 0.4 | 2.9 | · | 6.1 | 6.2 | 7.5 | · | 3.4 | 4.3 | 3.2 | · | 5.0 | |
| P / Cash Flow | · | -2.9 | · | · | · | -12.4 | · | · | · | -59.2 | · | · | · | -33.4 | · | · | |
| Earnings Yield | -790.0% | -197.8% | · | -527.7% | -591.5% | -485.6% | · | -77.2% | -43.2% | -8.5% | · | -15.2% | -11.7% | -14.2% | · | -8.1% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Net Income | $-56M | $-56M | $-63M | $-75M | $-69M |
| Diluted EPS | $-19.65 | $-23.88 | $-2.25 | $-2.69 | $-2.51 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 4.1 | 7.5 | 16.4 | 18.0 | 34.5 |
| Quick Ratio | 2.5 | 2.9 | 1.9 | 2.9 | 1.9 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | · | $-41M | $-54M | $-56M | $-60M |
Institutional owners (13F) 31 filers · $4.0M total · As of Sept. 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
31
Value held
$4.0M
New positions
11
Exited positions
7
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 11 (+4 vs prior Q) | 7 (+3 vs prior Q) | 8 (+5 vs prior Q) | 5 (+1 vs prior Q) | -434K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| VANGUARD GROUP INC | $1,304,203 | 91,910 | 32.76% | Shares |
| Ikarian Capital, LLC | $461,284 | 288,303 | 11.59% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $443,523 | 277,202 | 11.14% | Shares |
| Sofinnova Investments, Inc. | $356,246 | 222,654 | 8.95% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $273,923 | 171,202 | 6.88% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $250,947 | 156,842 | 6.30% | Shares |
| MILLENNIUM MANAGEMENT LLC | $140,979 | 88,112 | 3.54% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $135,499 | 84,687 | 3.40% | Shares |
| Squadron Capital Management LLC | $103,142 | 64,464 | 2.59% | Shares |
| Verdad Advisers, LP | $96,722 | 60,451 | 2.43% | Shares |
| Pfizer Inc | $72,967 | 44,347 | 1.83% | Shares |
| Affinity Asset Advisors, LLC | $67,136 | 41,960 | 1.69% | Shares |
| BlackRock, Inc. | $59,757 | 37,348 | 1.50% | Shares |
| JANE STREET GROUP, LLC | $52,360 | 32,725 | 1.32% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $47,855 | 29,905 | 1.20% | Shares |
| CARDIFF PARK ADVISORS, LLC | $34,933 | 21,833 | 0.88% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $25,814 | 16,134 | 0.65% | Shares |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $20,000 | 12,500 | 0.50% | Shares |
| DIADEMA PARTNERS LP | $12,387 | 7,742 | 0.31% | Shares |
| BARCLAYS PLC | $9,162 | 5,726 | 0.23% | Shares |
| SBI Securities Co., Ltd. | $5,010 | 1,000 | 0.13% | Shares |
| Persistent Asset Partners Ltd | $3,170 | 1,981 | 0.08% | Shares |
| Tower Research Capital LLC (TRC) | $2,781 | 1,738 | 0.07% | Shares |
| UBS Group AG | $951 | 594 | 0.02% | Shares |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | $133 | 83 | 0.00% | Shares |
| JPMORGAN CHASE & CO | $107 | 61 | 0.00% | Shares |
| MORGAN STANLEY | $106 | 66 | 0.00% | Shares |
| HRT FINANCIAL LP | $58 | 36,450 | 0.00% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $51 | 32 | 0.00% | Shares |
| ACADIAN ASSET MANAGEMENT LLC | $30 | 18,982 | 0.00% | Shares |
| Virtu Financial LLC | $18 | 10,991 | 0.00% | Shares |
Activists & 5%+ owners 3 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Sofinnova Venture Partners IX, L.P. ("SVP IX"), Sofinnova Management IX, L.L.C. ("SM IX"), Dr. James I. Healy ("Healy") | March 5, 2026 | 7.10% | Amendment | Passive investment | SEC |
| OrbiMed Advisors LLC, OrbiMed Capital GP VI LLC ×3 filings | March 8, 2024 | · | Initial filing | · | SEC |
| Sofinnova Venture Partners IX, L.P. (“SVP IX”), Sofinnova Management IX, L.L.C. (“SM IX”), Dr. Michael F. Powell (“Powell”), Dr. James I. Healy (“Healy”), Dr. Anand Mehra (“Mehra”) ×2 filings | Nov. 22, 2019 | · | Initial filing | Passive investment | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 24 insiders · 11 officers · 13 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Michael Richman | President & CEO | Jan. 30, 2026 A | · | 0 | 0 | $0 |
| Steven P. Cobourn | Chief Financial Officer | Jan. 30, 2026 A | · | 0 | 0 | $0 |
| Timothy Mayer | Chief Operating Officer | Jan. 30, 2026 A | · | 0 | 0 | $0 |
| Udayan Guha | Chief Medical Officer | Jan. 30, 2026 A | · | 0 | 0 | $0 |
| Kevin G. Shaw | Sr VP, General Counsel | Jan. 30, 2026 A | · | 0 | 0 | $0 |
| Sourav Kundu | Sr VP, Dev. & Mfg. | Jan. 30, 2026 A | · | 0 | 0 | $0 |
| Sol Langermann | Chief Scientific Officer | Jan. 31, 2025 A | · | 0 | 0 | $0 |
| Han Myint | Chief Medical Officer | March 29, 2024 A | · | 0 | 0 | $0 |
| Linda Liu | SVP, Research | Jan. 31, 2022 A | 55,234 | 0 | 0 | $0 |
| Kevin N. Heller | Chief Medical Officer | July 14, 2020 M | 49,011 | 0 | 0 | $0 |
| James B. Bingham | Chief Development Officer | Feb. 28, 2020 A | · | 0 | 0 | $0 |
| Anne Elizabeth Borgman | Director | June 18, 2026 A | · | 0 | 0 | $0 |
| Ellen Feigal | Director | June 18, 2026 A | · | 0 | 0 | $0 |
| John G Houston | Director | June 18, 2026 A | · | 0 | 0 | $0 |
| Stephen W Webster | Director | June 18, 2026 A | · | 0 | 0 | $0 |
| Elaine V Jones | Director | June 18, 2026 A | · | 0 | 0 | $0 |
| KABAKOFF DAVID S | Director | June 18, 2026 A | · | 0 | 0 | $0 |
| Garry A Nicholson | Director | June 22, 2023 A | · | 0 | 0 | $0 |
| Chau Quang Khuong | Director | June 22, 2023 A | 2,711,013 | 0 | 0 | $0 |
| Stella Xu | Director | June 24, 2021 A | 1,103,570 | 0 | 0 | $0 |
| Judith Li | Director | June 11, 2020 A | · | 0 | 0 | $0 |
| Briggs Morrison | Director | June 11, 2020 A | · | 0 | 0 | $0 |
| Timothy M Shannon | Director | June 13, 2019 A | 2,254,442 | 0 | 0 | $0 |
| Alexandria Venture Investments, LLC | 10% owner | May 13, 2019 C | 197,993 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 4 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
NXTC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 7 analysts
BUY
Median target
$20.00
+301.6%
2 28.6%
Strong Buy
4 57.1%
Buy
1 14.3%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
1 analysts · 2026-10-24Mean target $20.00 +301.6%
Low$20.00
Mean$20.00
High$20.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
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Source: SEC 10-Q filed Aug 6, 2026