SLS SELLAS Life Sciences Group, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$13.06
Price · Aug 19, 2026
Fundamentals as of Aug 11, 2026

About SELLAS Life Sciences Group, Inc. - Common Stock Company overview from Wikipedia

Galena Biopharma, Inc. was a publicly traded pharmaceutical company based in San Ramon, California. The company was founded in Worcester, Massachusetts. In 2011, it moved to Oregon, and in 2015 moved to San Ramon, California. Mark Schwartz was the company's president and chief executive officer. As of December 29, 2017, the company was acquired by Sellas Life Sciences Group Ltd. through a reverse merger transaction. Galena Biopharma was renamed to Sellas Life Sciences Group, Inc..

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Galena Biopharma, Inc. (originally RXi Pharmaceuticals) was a publicly traded pharmaceutical company based in San Ramon, California. The company was founded in Worcester, Massachusetts. In 2011, it moved to Oregon, and in 2015 moved to San Ramon, California. Mark Schwartz was the company's president and chief executive officer. As of December 29, 2017, the company was acquired by Sellas Life Sciences Group Ltd. through a reverse merger transaction. Galena Biopharma was renamed to Sellas Life Sciences Group, Inc. (Nasdaq: SLS).

History

In November 2006, Argonaut Pharmaceuticals, Inc. changed the name to RXi Pharmaceuticals Corporation. RXi was a subsidiary of CytRx Corp., which provided $15 million in financing in April 2007. RXi was founded in part by Nobel Prize winner Craig Mello. In September 2007, RXi signed a licensing deal with TriLink Biotechnologies, a competitor in the RNA interference (RNAi) field, in which RXi would pay TriLink to use three of TriLink's technologies.

In March 2011, the company announced the planned acquisition of Arizona-based Apthera, Inc. for $7 million. The acquisition included the breast cancer drug NeuVax. In June 2011, NeuVax was approved by the United States Food and Drug Administration to start a stage three clinical trial.

In September 2011, the company separated its cancer therapies division. It was renamed Galena Biopharma Inc and moved to Lake Oswego, Oregon. RXi became a subsidiary of Galena and retained RNAi technologies. RXi Pharmaceuticals remained in Massachusetts as a publicly traded company. In January 2014, Galena bought Mills Pharmaceuticals. In April 2014, the company headquarters moved to Portland.

In November 2011, the company partnered with Genentech to combine drugs from each company for a cancer treatment. Galena is currently studying the combination of NeuVax and Herceptin in phase II trials.

Leadership

In March 2011, president and CEO Noah Beerman were replaced by Mark Ahn, and in August 2014, Ahn resigned and was replaced by Mark Schwartz. On January 31, 2017, Galena announced the resignation of Mark Schwartz effective that day, and reported in the same press release that it would be exploring strategic alternatives to maximize shareholder value going forward.

Stock

RXi went public in March 2008. CytRx retained 49% ownership of RXi's stock and gave shares of RXi to existing shareholders. Trading began on the Nasdaq market on March 12, 2008, under the ticker symbol of RXII. Fidelity Investments invested $8.5 million in the company in May 2008, followed by a $25 million private-equity investment by Yorkville in February 2009. In 2010, RXi received a National Institutes of Health grant of $600,000. By August 2010, the company had 30 employees. In April 2011, RXi raised about $12 million from a stock offering and received $580,000 in grants from the National Institutes of Health. The company reported a loss of $11.5 million loss for 2011.

In November 2012, an anonymous internet report caused Galena stock to decline. The company filed a lawsuit claiming the report was false and attempted to manipulate the stock. In 2014, Galena's involvement in a fraudulent stock promotion scheme was exposed. On February 1, 2014, analyst Matt Gravitt published an article that revealed Galena had paid MissionIR, DreamTeam brand, to promote Galena's stock. Galena's stock fell 20% following this revelation that received a heated response, and was one of the three most read articles in Seeking Alpha's history. Over the next few weeks, more revelations came out and the company admitted their stock promotion relationship and insider selling. Galena then disclosed that the SEC was investigation their relationship with The DreamTeam Group. By March 2014, five lawsuits were filed against Galena and several of its officers alleging that the company used misleading articles to boost stock prices. Motley Fool, discussing the 23% stock price drop during March 2015, noted there was stock dilution from the offering and also that Abstral's sales were below Galena's estimates from late 2013. Discussing the Motley Fool article, Portland Business Journal also noted the ongoing insider-trading lawsuits as a factor in the stock price. A few days later, Zacks Investment Research said Galena could be a "great candidate" to beat its earnings. In response, Galena's CEO said there were many positive aspects to the company, and that the lawsuits weren't a worry as they should get covered under Directors and officers liability insurance. The company moved to San Ramon, California, in the Bay Area in 2015.

Stock promotion scandal

The revelation that Galena was engaging in fraudulent stock promotion without adequate disclosure led to the investigation of other biotech companies who engaged in similar activities. Richard Pearson, an investor who went undercover to investigate the stock promotion firms, wrote an exposé on DreamTeam and its ties to articles about Galena, CytRx, and other companies on media websites. In April 2017, the Securities and Exchange Commission announced enforcement actions against 27 individuals and entities behind various alleged stock promotion schemes. Fraud charges were filed against three public companies, seven stock promotion or communications firms, and two company CEOs; also on this hit list are six individuals and nine writers.

Merger with Sellas Life Sciences

In 2017, Galena Biopharma Inc. announced a merger "with privately-held oncology company Sellas Life Sciences Group Ltd. in an all-stock transaction." The combined company was Sellas Life Science Group. The newly merged companies focused on the development of novel treatments for cancer.

Products

Galena acquired the experimental breast cancer drug NeuVax in 2011 and are currently in phase II trials to combine the drug with Genentech's Herceptin.

In 2013, Galena began selling its first developed drug, an analgesic for cancer pain named Abstral Sublingual.

Anagrelide controlled-released (GALE-401) was approved by the FDA for phase III clinical trials for the treatment of essential thrombocytosis in December 2016.

GALE-301 and GALE-302 are immunotherapies in phase I and II trials for ovarian and breast cancers.

== References ==

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

SLS Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$13.06
Market Cap
$2.37B
P/E (TTM)
-61.9
EPS (TTM)
$-0.25
Revenue (TTM)
$0
Div Yield
ROE
-55.4%
Debt/Equity
52W Range
$1 – $16

SLS Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $0
5-point trend, +0.00
2019-12-31 2023-12-31
EPS $-0.25
6-point trend, +88.2%
2020-12-31 2025-12-31
Free Cash Flow
2016-12-31 2016-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
SLS
Peer Median
P/E (TTM)
5-point trend, -265.4%
-61.9
55.4
P/B
5-point trend, +88.5%
33.4
6.4

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
SLS
Peer Median
ROA
5-point trend, +4.0%
-54.9%
-32.7%
ROE
5-point trend, +37.2%
-55.4%
-37.9%
ROIC
5-point trend, +67.5%
-39.9%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
SLS
Peer Median
Current Ratio
5-point trend, +131.7%
10.7
9.7
Quick Ratio
5-point trend, +138.7%
10.2

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
SLS
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
SLS
Peer Median
EPS (Diluted)
5-point trend, +81.3%
$-0.25

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
SLS
Peer Median

SLS Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 6 analysts
  • Strong Buy 1 16.7%
  • Buy 4 66.7%
  • Hold 1 16.7%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

2 analysts · 2026-08-14
Median target $27.50 +110.5%
Mean target $27.50 +110.5%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.02%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.05 $-0.04 -0.01%
Dec. 31, 2025 $-0.05 $-0.07 0.02%
Sept. 30, 2025 $-0.06 $-0.07 0.01%
June 30, 2025 $-0.07 $-0.08 0.01%
March 31, 2025 $-0.07 $-0.11 0.04%
Dec. 31, 2024 $-0.08 $-0.11 0.03%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
SLS $577M -15.1 -55.4%
IRON $3.01B -13.2 -31.3%
BEAM $2.82B -34.2 120.0% -57.2% -7.0%
NRIX $1.80B -5.8 53.9% -314.9% -53.6%
RARE $2.22B -3.9 20.2% -85.4% -1613.2%
KOD $1.73B -6.5 -202.0%
BCRX $1.66B 6.4 94.1% 30.2% -97.6%
PGEN $1.48B -3.1 146.7% -2588.2% 3159.1%
CDNA $959M -47.1 13.8% -5.6% -6.8%
COAG

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 6-point trend, -100.0% · · $0 $1M $8M $2M $0 · · · · $9M
Cost of Revenue 7-point trend, -100.0% $0 $0 $0 $100.0K $200.0K $0 · · · · · $1M
R&D Expense 6-point trend, +37.6% · · · · $16M $9M $7M $9M $6M $11M · ·
SG&A Expense 10-point trend, +166.8% $12M $12M $14M $13M $11M $10M $10M $13M $15M $5M · ·
Operating Expenses 12-point trend, -35.6% $28M $32M $38M $43M $33M $19M $20M $31M $23M $32M $34M $44M
Operating Income 11-point trend, +35.6% $-28M $-32M $-38M $-42M $-25M $-17M $-20M · $-23M $-16M $-34M $-44M
Other Non-op 12-point trend, +730.0% $1M $632.0K $529.0K $649.0K $4M $208.0K $-19M $-29M $-24M $5M $509.0K $170.0K
Pretax Income 12-point trend, +5.0% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-29M $-24M $-18M $-39M $-28M
Income Tax 12-point trend, +0.00 $0 $0 $0 $0 $-237.0K $-17.0K $-81.0K $-1M $300.0K $1.0K $365.0K $0
Net Income 12-point trend, +26.6% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-28M $-24M $-18M $-64M $-37M
EPS (Basic) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
EPS (Diluted) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
Shares (Basic) 6-point trend, +1267.1% 109,051,215 61,202,412 27,777,111 19,395,709 15,481,113 7,977,104 · · · · · ·
Shares (Diluted) 6-point trend, +1267.1% 109,051,215 61,202,412 27,777,111 19,395,709 15,481,113 7,977,104 · · · · · ·
EBITDA 8-point trend, +10.9% $-28M $-32M $-38M $-42M $-25M $-17M · · $-23M $-32M · ·
Balance Sheet 22
Annual Balance Sheet data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +203.6% $72M $14M $3M $17M $21M $35M $7M $5M $2M $6M $1M $24M
Receivables 2-point trend, -100.0% · · · · $0 · · · · · · $2M
Inventory 2-point trend, -100.0% · · · · · · · · · · $0 $655.0K
Prepaid Expense 12-point trend, +168.2% $3M $2M $542.0K $531.0K $2M $395.0K $557.0K $387.0K $337.0K $332.0K $1M $1M
Current Assets 12-point trend, +44.4% $75M $16M $3M $18M $23M $37M $8M $6M $13M $6M $54M $52M
PP&E (Net) 3-point trend, -30.2% · · · · · · · · · $199.0K $335.0K $285.0K
Goodwill 12-point trend, -67.5% $2M $2M $2M $2M $2M $2M $2M $2M $2M $6M $6M $6M
Total Assets 12-point trend, -2.7% $78M $19M $6M $21M $26M $46M $17M $17M $34M $6M $82M $80M
Accounts Payable 12-point trend, +56.3% $3M $4M $6M $3M $2M $5M $4M $4M $12M $840.0K $2M $2M
Accrued Liabilities 12-point trend, -60.3% $4M $5M $8M $6M $3M $2M $1M $2M $3M $4M $5M $9M
Current Liabilities 12-point trend, -74.2% $7M $10M $14M $16M $5M $12M $5M $6M $25M $6M $57M $27M
Capital Leases 8-point trend, +457000.00 $457.0K $457.0K $460.0K $573.0K $610.0K $825.0K $0 $0 · · · ·
Deferred Tax 5-point trend, -100.0% · · · · $0 $239.0K $262.0K $357.0K $2M · · ·
Total Liabilities 12-point trend, -82.8% $7M $10M $14M $16M $6M $18M $11M $12M $31M $11M $69M $43M
Long-term Debt 4-point trend, -100.0% · · · · · · · $0 $11M · $5M $8M
Total Debt 2-point trend, -33.0% · · · · · · · · $11M $16M · ·
Common Stock 12-point trend, +25.0% $15.0K $7.0K $3.0K $2.0K $2.0K $1.0K $1.0K $1.0K $1.0K $2.0K $15.0K $12.0K
Retained Earnings 10-point trend, -803.6% $-275M $-248M $-217M $-180M $-139M $-118M $-101M $-82M $-54M $-30M · ·
Treasury Stock Flat — no change across 3 periods · · · · · · · · · $4M $4M $4M
Stockholders' Equity 12-point trend, +91.2% $71M $9M $-8M $5M $20M $28M $6M $5M $2M $-5M $-12M $37M
Liabilities + Equity 12-point trend, -2.7% $78M $19M $6M $21M $26M $46M $17M $17M $34M $6M $82M $80M
Shares Outstanding 12-point trend, +39.9% 153,103,459 73,977,459 32,132,890 21,005,405 15,895,637 14,254,554 5,080,100 440,529 5,766,891 1,268,489 8,095,337 109,425,701
Cash Flow 17
Annual Cash Flow data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
D&A 3-point trend, -96.5% · · · · · · · · · $3.0K $107.0K $86.0K
Stock-based Comp 12-point trend, -58.1% $2M $2M $2M $2M $1M $578.0K $573.0K $395.0K $3M $354.0K $2M $5M
Deferred Tax 9-point trend, +0.00 · · · $0 $-239.0K $-22.0K $-95.0K $-1M $39.0K $-41.0K $365.0K $0
Amort. of Intangibles 3-point trend, -100.0% · · · · · · · $0 $2M · · $440.0K
Other Non-cash · · · · · · · · · $-24M · ·
Operating Cash Flow 12-point trend, +33.8% $-28M $-35M $-31M $-24M $-26M $-10M $-18M $-30M $-11M $-12M $-48M $-43M
CapEx 3-point trend, -89.5% · · · · · · · · · $6.0K $153.0K $57.0K
Investing Cash Flow 9-point trend, +100.0% · $0 $-6M $-4M $0 · · $0 $12M $-85.0K $10M $-6M
Debt Issued 3-point trend, +1500000.00 · · · · · · · · · $2M $0 $0
Net Debt Issued 2-point trend, -100.0% · · · · · · $0 · · $18M · ·
Stock Issued 11-point trend, -100.0% · $0 $289.0K $1M $9M $30M $16M $22M $6M $34M $47M $11M
Net Stock Activity 8-point trend, -100.0% · $0 $289.0K $1M $9M $30M $16M · $6M $34M · ·
Dividends Paid 3-point trend, +0.00 · · · · · · $0 $487.0K $0 · · ·
Financing Cash Flow 12-point trend, +255.7% $86M $47M $22M $24M $12M $38M $20M $23M $6M $16M $44M $24M
Net Change in Cash 12-point trend, +339.9% $58M $11M $-15M $-4M $-14M $28M $2M $-7M $7M $5M $6M $-24M
Taxes Paid Flat — no change across 2 periods $0 $0 · · · · · · · · · ·
Free Cash Flow · · · · · · · · · $-45M · ·
Profitability 7
Annual Profitability data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 4-point trend, -184.1% · · · -4195.0% -332.8% -893.8% · · 4986.8% · · ·
Net Margin 5-point trend, -180.3% · · · -4130.1% -272.4% -881.9% -16349.1% · 5141.6% · · ·
Pretax Margin 5-point trend, -181.2% · · · -4130.1% -275.5% -882.8% -16417.0% · 5086.8% · · ·
EBITDA Margin 4-point trend, -184.1% · · · -4195.0% -332.8% -893.8% · · 4986.8% · · ·
ROA 9-point trend, -72.6% -54.9% -240.8% -274.9% -174.9% -57.2% -53.5% -115.1% · -118.9% -31.8% · ·
ROE 9-point trend, +80.7% -55.4% -243.6% 632.7% -473.4% -88.2% -93.3% -340.3% · 1623.1% -287.3% · ·
ROIC 8-point trend, +44.8% -39.9% -332.9% 474.8% -864.8% -122.9% -60.7% · · -178.3% -72.3% · ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 9-point trend, +768.9% 10.7 1.7 0.2 1.1 4.6 3.0 1.6 · 0.5 1.2 · ·
Quick Ratio 9-point trend, +1619.8% 10.2 1.5 0.2 1.1 4.3 2.9 1.4 · 0.1 0.6 · ·
Debt / Equity 2-point trend, +827.7% · · · · · · · · 5.3 0.6 · ·
LT Debt / Equity · · · · · · · · 1.3 · · ·
Efficiency 1
Annual Efficiency data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 6-point trend, +100.0% · · 0.0 0.0 0.2 0.1 0.0 · -0.0 · · ·
Per Share 5
Annual Per Share data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 9-point trend, -75.5% $0.46 $0.13 $-0.25 $0.23 $1.28 $1.96 $1.20 · $0.36 $1.89 · ·
Revenue / Share 3-point trend, -100.0% · · $0.00 $0.05 $0.49 · · · · · · ·
Cash Flow / Share 5-point trend, +84.5% $-0.26 $-0.58 $-1.13 $-1.23 $-1.68 · · · · · · ·
Cash / Share 9-point trend, -60.6% $0.47 $0.19 $0.08 $0.82 $1.34 $2.48 $1.43 · $0.40 $1.19 · ·
EPS (TTM) 6-point trend, +88.2% $-0.25 $-0.50 $-1.34 $-2.13 $-1.34 $-2.11 · · · · · ·
Growth Rates 1
Annual Growth Rates data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 2-point trend, -128.9% · · · -86.8% 300.0% · · · · · · ·
Valuation (TTM) 17
Annual Valuation (TTM) data for SLS
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, -100.0% $0 $0 $0 $1M $8M $2M $0 $10M $10M $10M $10M $9M
Net Income TTM 12-point trend, +26.6% $-27M $-31M $-37M $-41M $-21M $-17M $-19M $-28M $-24M $-18M $-64M $-37M
Market Cap 9-point trend, -98.7% $577M $77M $34M $50M $88M $83M $22M · $2.25B $44.20B · ·
Enterprise Value 2-point trend, -94.9% · · · · · · · · $2.26B $44.20B · ·
P/E 6-point trend, -447.6% -15.1 -2.1 -0.8 -1.1 -4.1 -2.8 · · · · · ·
P/S 5-point trend, -98.9% · · · 49.6 11.6 43.6 · · 223.1 4384.0 · ·
P/B 9-point trend, -99.5% 8.1 8.1 -4.3 10.2 4.3 3.0 3.6 · 1086.5 1542.5 · ·
P / Tangible Book 5-point trend, +163.3% 8.4 10.2 · 16.9 4.8 3.2 · · · · · ·
P / Cash Flow 9-point trend, +97.9% -20.3 -2.2 -1.1 -2.1 -3.4 -8.0 -1.2 · -204.7 -984.2 · ·
P / FCF · · · · · · · · · -984.0 · ·
EV / EBITDA 2-point trend, +93.0% · · · · · · · · -98.0 -1393.3 · ·
EV / FCF · · · · · · · · · -984.0 · ·
EV / Revenue 2-point trend, -94.9% · · · · · · · · 223.9 4383.9 · ·
Dividend Yield Flat — no change across 2 periods · · · · · · 0.00% · 0.00% · · ·
Earnings Yield 6-point trend, +81.7% -6.6% -48.1% -126.4% -90.2% -24.2% -36.3% · · · · · ·
Payout Ratio · · · · · · 0.00% · · · · ·
Annual Payout 3-point trend, +0.00 · · · · · · $0 $487.0K $0 · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $0$1M$8M
Operating Margin % -4195.0%-332.8%
Net Income $-27M$-31M$-37M$-41M$-21M
Diluted EPS $-0.25$-0.50$-1.34$-2.13$-1.34
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 10.71.70.21.14.6
Quick Ratio 10.21.50.21.14.3

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 232 filers · $1.2B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
88 (+21 vs prior Q) 19 (+4 vs prior Q) 70 (+12 vs prior Q) 38 (+15 vs prior Q) +29.5M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
STATE STREET CORP $191,829,196 12,996,558 15.97% Shares
VANGUARD CAPITAL MANAGEMENT LLC $121,417,310 8,226,105 10.11% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $105,640,272 7,157,200 8.79% Call option
Anson Funds Management LP $66,420,000 4,500,000 5.53% Shares
CITADEL ADVISORS LLC $64,157,292 4,346,700 5.34% Call option
GEODE CAPITAL MANAGEMENT, LLC $61,905,400 4,193,009 5.15% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $61,832,592 4,189,200 5.15% Put option
CITADEL ADVISORS LLC $33,333,984 2,258,400 2.77% Put option
VANGUARD PORTFOLIO MANAGEMENT LLC $31,897,821 2,161,099 2.66% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $30,266,812 2,050,597 2.52% Shares
JONES FINANCIAL COMPANIES LLLP $28,553,511 2,304,561 2.38% Shares
VANGUARD GROUP INC $27,868,421 7,392,154 2.32% Shares
Anson Funds Management LP $27,245,484 1,845,900 2.27% Put option
PERCEPTIVE ADVISORS LLC $22,140,000 1,500,000 1.84% Put option
VANGUARD FIDUCIARY TRUST CO $19,707,050 1,335,166 1.64% Shares
Sio Capital Management, LLC $18,165,132 1,230,700 1.51% Put option
BNP PARIBAS FINANCIAL MARKETS $15,823,045 1,072,022 1.32% Shares
MILLENNIUM MANAGEMENT LLC $13,372,560 906,000 1.11% Put option
BARCLAYS PLC $11,831,616 801,600 0.98% Put option
Anson Funds Management LP $11,808,000 800,000 0.98% Call option
BNP PARIBAS FINANCIAL MARKETS $11,734,200 7,950 0.98% Put option
JANE STREET GROUP, LLC $11,058,192 749,200 0.92% Call option
MORGAN STANLEY $9,922,380 672,248 0.83% Shares
BANK OF AMERICA CORP /DE/ $9,150,359 619,943 0.76% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $8,339,518 565,008 0.69% Shares
JANE STREET GROUP, LLC $7,462,700 505,603 0.62% Shares
Balyasny Asset Management L.P. $7,380,000 500,000 0.61% Put option
LMR Partners LLP $6,642,000 450,000 0.55% Put option
NOMURA HOLDINGS INC $6,273,000 425,000 0.52% Call option
DIADEMA PARTNERS LP $5,904,000 400,000 0.49% Call option
Swiss National Bank $5,319,504 360,400 0.44% Shares
XTX Topco Ltd $5,300,168 359,090 0.44% Shares
Ikarian Capital, LLC $5,235,372 354,700 0.44% Put option
CITIGROUP INC $4,659,717 315,699 0.39% Shares
RENAISSANCE TECHNOLOGIES LLC $4,580,973 310,364 0.38% Shares
DAGCO, INC. $4,351,740 1,028,780 0.36% Shares
Everhart Financial Group, Inc. $4,251,146 288,018 0.35% Shares
Rafferty Asset Management, LLC $3,540,806 239,892 0.29% Shares
RHUMBLINE ADVISERS $3,400,726 230,402 0.28% Shares
Walleye Capital LLC $3,377,088 228,800 0.28% Put option
GOLDMAN SACHS GROUP INC $3,125,991 211,788 0.26% Shares
TUDOR INVESTMENT CORP ET AL $3,087,792 209,200 0.26% Put option
WELLINGTON MANAGEMENT GROUP LLP $2,992,738 202,760 0.25% Shares
BOOTHBAY FUND MANAGEMENT, LLC $2,982,996 202,100 0.25% Put option
Jefferies Financial Group Inc. $2,958,775 200,459 0.25% Shares
Jefferies Financial Group Inc. $2,953,476 200,100 0.25% Put option
Mariner, LLC $2,925,609 198,212 0.24% Shares
MILLENNIUM MANAGEMENT LLC $2,895,912 196,200 0.24% Call option
Bank of New York Mellon Corp $2,801,212 189,784 0.23% Shares
ALPS ADVISORS INC $2,776,459 188,107 0.23% Shares
JANE STREET GROUP, LLC $2,405,880 163,000 0.20% Put option
LPL Financial LLC $2,297,586 155,663 0.19% Shares
SIMPLEX TRADING, LLC $2,274,501 154,099 0.19% Shares
BlackRock, Inc. $2,222,708 150,590 0.19% Shares
WELLS FARGO & COMPANY/MN $2,208,775 149,646 0.18% Shares
Vontobel Holding Ltd. $2,166,207 146,762 0.18% Shares
TUDOR INVESTMENT CORP ET AL $2,069,352 140,200 0.17% Call option
Vanguard Global Advisers, LLC $1,918,874 130,005 0.16% Shares
VANGUARD ASSET MANAGEMENT, Ltd $1,859,598 125,989 0.15% Shares
Caption Management, LLC $1,845,000 125,000 0.15% Put option
PROFUND ADVISORS LLC $1,780,159 120,607 0.15% Shares
MetLife Investment Management, LLC $1,624,810 110,082 0.14% Shares
Daiwa Securities Group Inc. $1,589,652 107,700 0.13% Put option
Daiwa Securities Group Inc. $1,512,900 102,500 0.13% Shares
DIADEMA PARTNERS LP $1,476,000 100,000 0.12% Put option
HIGHBRIDGE CAPITAL MANAGEMENT LLC $1,467,144 99,400 0.12% Shares
STATE OF WISCONSIN INVESTMENT BOARD $1,405,300 95,210 0.12% Shares
Harvest Investment Services, LLC $1,394,554 94,482 0.12% Shares
ORBIMED ADVISORS LLC $1,365,300 92,500 0.11% Put option
Zurcher Kantonalbank (Zurich Cantonalbank) $1,229,582 83,305 0.10% Shares
Invesco Ltd. $1,104,816 74,852 0.09% Shares
Gotham Asset Management, LLC $1,097,317 74,344 0.09% Shares
FULCRUM WEALTH ADVISORS, LLC $1,081,214 73,253 0.09% Shares
ALLIANCEBERNSTEIN L.P. $998,534 236,060 0.08% Shares
NEW YORK STATE COMMON RETIREMENT FUND $978,588 66,300 0.08% Shares
Verition Fund Management LLC $916,596 62,100 0.08% Put option
OSAIC HOLDINGS, INC. $889,776 60,284 0.07% Shares
FIFTH THIRD BANCORP $888,404 60,190 0.07% Shares
State of New Jersey Common Pension Fund D $857,069 58,067 0.07% Shares
Verition Fund Management LLC $832,464 56,400 0.07% Call option
Police & Firemen's Retirement System of New Jersey $821,630 55,666 0.07% Shares
ARIZONA STATE RETIREMENT SYSTEM $731,388 49,552 0.06% Shares
Caption Management, LLC $728,745 49,373 0.06% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $722,310 48,937 0.06% Shares
Russell Investments Group, Ltd. $704,494 47,730 0.06% Shares
SIG BROKERAGE, LP $689,292 46,700 0.06% Call option
Vanguard Investments Australia, Ltd. $684,643 46,385 0.06% Shares
COMMONWEALTH EQUITY SERVICES, LLC $665,481 45,087 0.06% Shares
INSTRUMENTAL WEALTH, LLC $662,931 44,914 0.06% Shares
Persistent Asset Partners Ltd $655,647 758 0.05% Call option
Virtus Investment Advisers, LLC $616,791 41,788 0.05% Shares
Accurate Wealth Management, LLC $614,707 47,462 0.05% Shares
AXXCESS WEALTH MANAGEMENT, LLC $610,665 41,373 0.05% Shares
KLP KAPITALFORVALTNING AS $600,732 40,700 0.05% Shares
SJS Investment Consulting Inc. $590,400 40,000 0.05% Shares
Wealthfront Advisers LLC $587,773 39,822 0.05% Shares
Quantinno Capital Management LP $546,651 37,036 0.05% Shares
Visionary Horizons, LLC $531,360 36,000 0.04% Shares
Kestra Advisory Services, LLC $516,305 34,980 0.04% Shares
NORTHSTAR ASSET MANAGEMENT Co $509,400 45,000 0.04% Shares

Company insiders 42 insiders · 17 officers · 9 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Andelos M. Stergiou President and CEO June 16, 2026 A 1,759,183 0 0 $0
Noah D Beerman CEO and President March 15, 2011 A 92,994 0 0 $0
John Thomas Burns CFO Jan. 7, 2026 A 554,327 0 0 $0
Gene Mack CFO and Treasurer April 20, 2018 A 0 0 $0
Robert Eugene Kennedy Vice President and CFO April 13, 2011 A 379,294 0 0 $0
Stephen J. Dipalma CFO, EVP, Secretary Jan. 15, 2009 A 0 0 $0
Dragan Cicic SVP, Chief Development Officer Jan. 7, 2026 A 557,805 0 0 $0
Robert Francomano Chief Commercial Officer Jan. 22, 2024 A 40,918 0 0 $0
Barbara A Wood EVP, Gen. Counsel, Corp. Sec. Jan. 22, 2024 A 117,225 0 0 $0
Nicholas J. Sarlis Chief Medical Officer and SVP March 14, 2019 A 0 0 $0
Gregory M Torre CRO and SVP March 13, 2018 A 0 0 $0
Amy B Tata Principlw Acctg Officer & Cont March 15, 2011 A 14,065 0 0 $0
Ramani Varanasi VP Business Development March 15, 2011 A 41,083 0 0 $0
Anastasia Khvorova Chief Science Officer March 15, 2011 A 60,559 0 0 $0
Pamela Pavco VP of Pharmaceutical Devlpmt March 15, 2011 A 44,940 0 0 $0
Konstantinos Andrikopoulos VP, Legal April 15, 2010 A 5,750 0 0 $0
Dmitry Samarsky VP, Technology Development March 31, 2010 S 0 0 0 $0
Katherine Bach Kalin Director Jan. 7, 2026 A 154,400 1 0 $100,806
John Varian Director Jan. 7, 2026 A 72,900 0 0 $0
Jane Wasman Director Jan. 7, 2026 A 92,900 0 0 $0
David A Scheinberg Director Jan. 7, 2026 A 73,082 0 0 $0
Robert L Van Nostrand Director Jan. 7, 2026 A 82,900 0 0 $0
Stephen F Ghiglieri Director March 14, 2019 A 0 0 $0
Fabio Lopez Director June 12, 2018 A 0 0 $0
Irving M. Einhorn Oct. 10, 2017 A 34,690 0 0 $0
William Ashton Oct. 10, 2017 A 38,154 0 0 $0
Richard Chin Oct. 10, 2017 A 31,339 0 0 $0
Rudolph Nisi Oct. 10, 2017 A 42,918 0 0 $0
Sanford Hillsberg Oct. 10, 2017 A 56,950 0 0 $0
Mary Ann Gray Oct. 10, 2017 A 39,167 0 0 $0
Stephen S Galliker Oct. 10, 2017 A 36,039 0 0 $0
Thomas J Knapp Feb. 6, 2017 A 0 0 $0
Bijan Nejadnik Jan. 17, 2017 A 0 0 $0
Ryan Dunlap June 1, 2016 M 18,702 0 0 $0
Mark W. Schwartz Dec. 18, 2015 A 415,972 0 0 $0
Steven A Kriegsman June 19, 2015 A 5,000 0 0 $0
Margaret Kivinski Jan. 16, 2015 A 0 0 $0
Brian L Hamilton June 30, 2014 J 2,461 0 0 $0
Mark J Ahn June 30, 2014 A 116,225 0 0 $0
Rosemary Mazanet Jan. 29, 2013 A 0 0 $0
CYTRX CORP Dec. 29, 2010 S 0 0 0 $0
Tod Woolf Jan. 15, 2009 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 2 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Equilibria Capital Management Limited (2), EQC Private Markets SAC Fund II Ltd — EQC Biotech Sely S Fund (2), EQC Private Markets SAC Fund Ltd — EQC Biotech Sely I Fund (2), EQC Private Markets SAC Fund Ltd — EQC Biotech Sely II Fund (2), EQC Private Markets II SAC Fund Ltd — EQC Biotech Sely III Fund (2), Varibobi Financial Holdings Ltd. (2), Daniel Tafur (2), Fabio López (2) ×4 filings Oct. 10, 2018 Initial filing SEC
Angelos M. Stergiou, M.D., Sc.D. h.c. Jan. 8, 2018 Initial filing M&A / sale SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 29 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
LABU · Direxion Shares ETF Trust 0.26% 268,465 NS April 30, 2026 N-PORT
CANC · Tema ETF Trust 0.22% 40,702 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.05% 51,293 NS May 31, 2026 N-PORT
ITWO · ProShares Trust 0.04% 8,088 NS May 31, 2026 N-PORT
RSSL · Global X Funds 0.03% 74,459 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.02% 6,326 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.02% 6,397 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.01% 161 NS May 31, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.01% 64,480 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 3,554 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTI · VANGUARD INDEX FUNDS July 15, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND July 30, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
ITOT · iShares Trust July 22, 2026 Daily
IWV · iShares Trust Aug. 18, 2026 Daily
IWO · iShares Trust Aug. 18, 2026 Daily
IWM · iShares Trust Aug. 18, 2026 Daily
IWC · iShares Trust Aug. 18, 2026 Daily
ICOP · iShares Trust Aug. 18, 2026 Daily
VHT · VANGUARD WORLD FUND July 20, 2026 Daily
PICK · iShares, Inc. Aug. 14, 2026 Daily
ISCB · iShares Trust July 21, 2026 Daily
ISCG · iShares Trust July 21, 2026 Daily
ISCF · iShares Trust Aug. 10, 2026 Daily
WSML · iShares Trust Aug. 10, 2026 Daily
DWAS · Invesco Exchange-Traded Fund Trust … July 20, 2026 Daily