IRON Disc Medicine, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$80.86
Price · Aug 19, 2026
Fundamentals as of Jul 30, 2026

IRON Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$80.86
Market Cap
$3.06B
P/E (TTM)
-13.5
EPS (TTM)
$-6.01
Revenue (TTM)
Div Yield
ROE
-31.3%
Debt/Equity
52W Range
$56 – $100

IRON Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
EPS $-6.01
5-point trend, +85.3%
2021-12-31 2025-12-31
Free Cash Flow $-181M
5-point trend, -203.4%
2021-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
IRON
Peer Median
P/E (TTM)
5-point trend, -519.8%
-13.5
P/B
5-point trend, -86.5%
4.1
3.3
Price / FCF
5-point trend, +73.7%
-16.9

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
IRON
Peer Median
ROA
5-point trend, +66.3%
-32.6%
-36.2%
ROE
5-point trend, +42.1%
-31.3%
-43.7%
ROIC
3-point trend, -20.9%
-32.0%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
IRON
Peer Median
Current Ratio
5-point trend, +132.3%
21.9
9.7
Quick Ratio
5-point trend, +134.4%
21.6

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
IRON
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
IRON
Peer Median
EPS (Diluted)
5-point trend, +85.3%
$-6.01

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
IRON
Peer Median

IRON Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 19 analysts
  • Strong Buy 7 36.8%
  • Buy 11 57.9%
  • Hold 1 5.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

12 analysts · 2026-08-15
Median target $100.00 +23.7%
Mean target $101.17 +25.1%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.01%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-1.54 $-1.78 0.24%
March 31, 2026 $-1.65 $-1.75 0.10%
Dec. 31, 2025 $-1.64 $-1.78 0.14%
Sept. 30, 2025 $-1.77 $-1.49 -0.28%
June 30, 2025 $-1.58 $-1.18 -0.40%
March 31, 2025 $-1.02 $-1.16 0.14%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
IRON $3.01B -13.2 -31.3%
CLDX $1.81B -7.0 -78.0% -16748.0% -43.8%
GRAL $3.45B -7.7 17.2% -277.5% -16.7%
ARQT $3.58B -223.4 91.3% -4.3% -9.8%
IOVA $1.12B -2.5 60.6% -148.4% -56.0%
IMNM $2.43B -8.8 -23.2% -3060.0% -47.0%
NRIX $1.80B -5.8 53.9% -314.9% -53.6%
BEAM $2.82B -34.2 120.0% -57.2% -7.0%
SLS $577M -15.1 -55.4%
RARE $2.22B -3.9 20.2% -85.4% -1613.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for IRON
Metric Trend 202520242023202220212020
R&D Expense 6-point trend, +505.8% $171M $97M $69M $33M $25M $28M
SG&A Expense 6-point trend, +1013.8% $65M $33M $22M $14M $6M $6M
Operating Expenses 6-point trend, +593.4% $236M $130M $91M $47M $31M $34M
Operating Income 6-point trend, -593.4% $-236M $-130M $-91M $-47M $-31M $-34M
Interest Expense 2-point trend, -68.4% · · · · $2M $7M
Other Non-op 5-point trend, +100.9% $45.0K $-2.0K $-2.0K $0 $-5M ·
Pretax Income 4-point trend, -352.4% $-212M $-109M $-76M $-47M · ·
Income Tax 4-point trend, +361000.00 $361.0K $355.0K $99.0K $0 · ·
Net Income 6-point trend, -419.6% $-212M $-109M $-76M $-47M $-36M $-41M
EPS (Basic) 5-point trend, +85.3% $-6.01 $-3.96 $-3.42 $-45.05 $-40.95 ·
EPS (Diluted) 5-point trend, +85.3% $-6.01 $-3.96 $-3.42 $-45.05 $-40.95 ·
Shares (Basic) 5-point trend, +3918.1% 35,295,663 27,606,022 22,315,877 1,039,490 878,407 ·
Shares (Diluted) 5-point trend, +3918.1% 35,295,663 27,606,022 22,315,877 1,039,490 878,407 ·
EBITDA 5-point trend, -241.6% $-236M $-130M $-91M $-47M $-69M ·
Balance Sheet 22
Annual Balance Sheet data for IRON
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, +1924.1% $91M $192M $360M $195M $88M $5M
Short-term Investments 3-point trend, +700007000.00 $700M $297M $0 · · ·
Prepaid Expense 6-point trend, +2168.0% $13M $4M $5M $4M $2M $562.0K
Current Assets 6-point trend, +15771.6% $804M $494M $366M $198M $90M $5M
PP&E (Net) 6-point trend, +294.2% $1M $751.0K $170.0K $168.0K $106.0K $294.0K
PP&E (Gross) 2-point trend, -100.0% · · · · $0 $955.0K
Accum. Depreciation 5-point trend, -39.3% · $401.0K $245.0K $145.0K $56.0K $661.0K
Other Non-current Assets 5-point trend, +303.3% $726.0K $838.0K $234.0K $116.0K $180.0K ·
Total Assets 6-point trend, +9599.2% $807M $497M $368M $200M $92M $8M
Accounts Payable 6-point trend, +279.4% $9M $8M $13M $16M $3M $2M
Accrued Liabilities 6-point trend, +3059.0% $16M $8M $6M $6M $4M $492.6K
Current Liabilities 6-point trend, +47.3% $37M $23M $21M $23M $13M $25M
Capital Leases 5-point trend, -6.1% $1M $2M $1M $1M $1M ·
Total Liabilities 6-point trend, +122.2% $67M $53M $23M $24M $15M $30M
Long-term Debt 4-point trend, +108.3% $29M $28M $0 · · $14M
Common Stock 6-point trend, +100.0% $4.0K $3.0K $2.0K $2.0K $0 $2.0K
Paid-in Capital 6-point trend, +1273.2% $1.25B $741M $534M $289M $1M $91M
Retained Earnings 6-point trend, -352.2% $-510M $-298M $-189M $-112M $-65M $-113M
AOCI 3-point trend, +965000.00 $965.0K $289.0K $0 · · ·
Stockholders' Equity 6-point trend, +2668.0% $740M $444M $345M $177M $-64M $-29M
Liabilities + Equity 6-point trend, +9599.2% $807M $497M $368M $200M $92M $8M
Shares Outstanding 6-point trend, +143.4% 37,890,616 29,865,030 24,360,233 17,403,315 909,418 15,565,380
Cash Flow 15
Annual Cash Flow data for IRON
Metric Trend 202520242023202220212020
D&A 5-point trend, +778.1% $281.0K $156.0K $100.0K $89.0K $32.0K ·
Stock-based Comp 6-point trend, +3393.4% $34M $17M $6M $2M $507.0K $983.0K
Deferred Tax $0 · · · · ·
Other Non-cash 4-point trend, -218.1% $-3M $-2M $-3M $2M · ·
Operating Cash Flow 6-point trend, -451.5% $-180M $-94M $-73M $-42M $-28M $-33M
CapEx 6-point trend, +4140.9% $933.0K $505.0K $89.0K $151.0K $68.0K $22.0K
Investing Cash Flow 6-point trend, -1792168.2% $-394M $-292M $-89.0K $-151.0K $-68.0K $-22.0K
Debt Issued 3-point trend, +0.00 $0 $29M $0 · · ·
Net Debt Issued 2-point trend, -100.0% $0 $29M · · · ·
Stock Issued 4-point trend, -100.0% · · $0 $54M $0 $20M
Net Stock Activity 3-point trend, +0.00 · · $0 $54M $0 ·
Financing Cash Flow 6-point trend, +1282.3% $473M $218M $239M $149M $90M $34M
Net Change in Cash 6-point trend, -6776.7% $-101M $-168M $166M $107M $62M $2M
Taxes Paid 5-point trend, +349000.00 $349.0K $300.0K $100.0K $0 $0 ·
Free Cash Flow 5-point trend, -203.4% $-181M $-94M $-74M $-42M $-60M ·
Profitability 3
Annual Profitability data for IRON
Metric Trend 202520242023202220212020
ROA 5-point trend, +66.3% -32.6% -25.3% -26.9% -32.0% -96.6% ·
ROE 5-point trend, +42.1% -31.3% -24.0% -21.7% -120.0% -54.1% ·
ROIC 3-point trend, -20.9% -32.0% -29.3% -26.4% · · ·
Liquidity & Solvency 3
Annual Liquidity & Solvency data for IRON
Metric Trend 202520242023202220212020
Current Ratio 6-point trend, +879.8% 21.9 21.2 17.1 8.8 9.4 2.2
Quick Ratio 6-point trend, +964.5% 21.6 21.0 16.8 8.6 9.2 2.0
Interest Coverage · · · · -32.0 ·
Per Share 4
Annual Per Share data for IRON
Metric Trend 202520242023202220212020
Book Value / Share 5-point trend, +575.8% $19.53 $14.85 $14.17 $10.15 $2.89 ·
Cash Flow / Share 4-point trend, +87.4% $-5.11 $-3.40 $-3.29 $-40.65 · ·
Cash / Share 5-point trend, -23.9% $2.41 $6.44 $14.79 $11.18 $3.16 ·
EPS (TTM) 5-point trend, +85.3% $-6.01 $-3.96 $-3.42 $-45.05 $-40.95 ·
Valuation (TTM) 8
Annual Valuation (TTM) data for IRON
Metric Trend 202520242023202220212020
Net Income TTM 6-point trend, -419.6% $-212M $-109M $-76M $-47M $-36M $-41M
Market Cap 5-point trend, -20.2% $3.01B $1.89B $1.41B $346M $3.77B ·
P/E 5-point trend, -519.8% -13.2 -16.0 -16.9 -0.4 -2.1 ·
P/B 5-point trend, -86.5% 4.1 4.3 4.1 2.0 30.2 ·
P / Tangible Book 4-point trend, +107.5% 4.1 4.3 4.1 2.0 · ·
P / Cash Flow 5-point trend, +73.6% -16.7 -20.2 -19.2 -8.2 -63.2 ·
P / FCF 5-point trend, +73.7% -16.6 -20.1 -19.1 -8.2 -63.1 ·
Earnings Yield 5-point trend, +83.9% -7.6% -6.2% -5.9% -226.5% -46.9% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-212M$-109M$-76M$-47M$-36M
Diluted EPS $-6.01$-3.96$-3.42$-45.05$-40.95
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 21.921.217.18.89.4
Quick Ratio 21.621.016.88.69.2
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-181M$-94M$-74M$-42M$-60M

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Institutional owners (13F) 239 filers · $2.5B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
52 (+3 vs prior Q) 21 (-16 vs prior Q) 73 (-9 vs prior Q) 64 (+24 vs prior Q) +3.2M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FMR LLC $206,953,287 2,829,550 8.25% Shares
RA CAPITAL MANAGEMENT, L.P. $179,209,164 2,450,221 7.14% Shares
VANGUARD GROUP INC $120,966,365 1,523,314 4.82% Shares
STATE STREET CORP $120,595,865 1,648,836 4.81% Shares
Vestal Point Capital, LP $113,367,000 1,550,000 4.52% Shares
Atlas Venture Life Science Advisors, LLC $110,724,818 1,513,875 4.41% Shares
VANGUARD CAPITAL MANAGEMENT LLC $100,130,635 1,369,027 3.99% Shares
Frazier Life Sciences Management, L.P. $99,093,875 1,354,852 3.95% Shares
TCG Crossover Management, LLC $98,143,787 1,341,862 3.91% Shares
WELLINGTON MANAGEMENT GROUP LLP $90,922,967 1,243,136 3.62% Shares
BVF INC/IL $84,375,182 1,153,612 3.36% Shares
Woodline Partners LP $70,088,672 958,281 2.79% Shares
Siren, L.L.C. $64,977,649 888,401 2.59% Shares
Logos Global Management LP $63,997,500 875,000 2.55% Shares
Opaleye Management Inc. $62,534,700 855,000 2.49% Shares
GEODE CAPITAL MANAGEMENT, LLC $49,411,270 675,408 1.97% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $48,052,980 657,000 1.92% Shares
Bellevue Group AG $40,958,400 560,000 1.63% Shares
DIMENSIONAL FUND ADVISORS LP $39,242,462 536,539 1.56% Shares
Saturn V Capital Management LP $38,378,752 524,730 1.53% Shares
ARMISTICE CAPITAL, LLC $33,644,400 460,000 1.34% Shares
JENNISON ASSOCIATES LLC $32,146,492 439,520 1.28% Shares
Aberdeen Group plc $32,048,046 438,174 1.28% Shares
Palo Alto Investors LP $30,473,488 416,646 1.21% Shares
EVENTIDE ASSET MANAGEMENT, LLC $28,938,480 395,651 1.15% Shares
Pictet Asset Management Holding SA $28,186,328 385,375 1.12% Shares
Assenagon Asset Management S.A. $28,097,316 384,158 1.12% Shares
Foresite Capital Management V, LLC $27,359,407 374,069 1.09% Shares
ORBIMED ADVISORS LLC $26,150,110 357,535 1.04% Shares
BAKER BROS. ADVISORS LP $25,573,913 349,657 1.02% Shares
LOOMIS SAYLES & CO L P $23,226,924 317,568 0.93% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $20,620,872 281,937 0.82% Shares
Octagon Capital Advisors LP $19,747,800 270,000 0.79% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $18,824,919 257,382 0.75% Shares
Checkpoint Capital L.P. $17,562,743 240,125 0.70% Shares
VANGUARD FIDUCIARY TRUST CO $16,470,982 225,198 0.66% Shares
BNP PARIBAS FINANCIAL MARKETS $13,508,592 184,695 0.54% Shares
Catalio Capital Management, LP $11,657,346 159,384 0.46% Shares
Caption Management, LLC $10,971,000 150,000 0.44% Call option
Sofinnova Investments, Inc. $10,695,920 146,239 0.43% Shares
Bain Capital Life Sciences Investors, LLC $10,329,855 141,234 0.41% Shares
TWO SIGMA INVESTMENTS, LP $10,001,895 136,750 0.40% Shares
Alyeska Investment Group, L.P. $9,142,500 125,000 0.36% Shares
Ensign Peak Advisors, Inc $8,931,199 122,111 0.36% Shares
Trexquant Investment LP $7,877,105 107,699 0.31% Shares
KENNEDY CAPITAL MANAGEMENT LLC $7,809,085 106,769 0.31% Shares
MILLENNIUM MANAGEMENT LLC $7,770,979 106,248 0.31% Shares
BANK OF AMERICA CORP /DE/ $6,884,814 94,132 0.27% Shares
SILVERARC CAPITAL MANAGEMENT, LLC $6,055,992 82,800 0.24% Shares
Squarepoint Ops LLC $5,549,278 75,872 0.22% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5,383,104 73,600 0.21% Call option
DNB Asset Management AS $5,348,509 73,127 0.21% Shares
GOLDMAN SACHS GROUP INC $4,960,721 67,825 0.20% Shares
Casdin Capital, LLC $4,754,100 65,000 0.19% Shares
SPHERA FUNDS MANAGEMENT LTD. $4,647,169 63,538 0.19% Shares
Bank of New York Mellon Corp $4,572,786 62,521 0.18% Shares
PEAK6 LLC $4,388,400 60,000 0.17% Call option
KVP Capital Advisors, LP $4,260,405 58,250 0.17% Shares
MOORE CAPITAL MANAGEMENT, LP $4,227,199 57,796 0.17% Shares
XTX Topco Ltd $4,147,769 56,710 0.17% Shares
NEXTBio Capital Management LP $3,851,187 52,655 0.15% Shares
ALGERT GLOBAL LLC $3,792,309 51,850 0.15% Shares
ExodusPoint Capital Management, LP $3,775,706 51,623 0.15% Shares
SCHRODER INVESTMENT MANAGEMENT GROUP $3,700,713 49,674 0.15% Shares
Burkehill Global Management, LP $3,657,000 50,000 0.15% Shares
Swiss National Bank $3,642,372 49,800 0.15% Shares
AMERIPRISE FINANCIAL INC $3,355,224 45,874 0.13% Shares
Atle Fund Management AB $3,194,901 43,682 0.13% Shares
Quadrature Capital Ltd $3,102,526 42,419 0.12% Shares
Brevan Howard Capital Management LP $3,063,542 41,886 0.12% Shares
ALPS ADVISORS INC $2,820,644 38,565 0.11% Shares
CITIGROUP INC $2,683,068 36,684 0.11% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $2,679,411 36,634 0.11% Shares
RHUMBLINE ADVISERS $2,621,620 35,844 0.10% Shares
LAZARD ASSET MANAGEMENT LLC $2,562,387 35,034 0.10% Shares
SEVEN GRAND MANAGERS, LLC $2,559,900 35,000 0.10% Shares
MARSHALL WACE, LLP $2,515,577 34,394 0.10% Shares
BANK OF MONTREAL /CAN/ $2,359,350 32,258 0.09% Shares
ALLIANCEBERNSTEIN L.P. $2,216,800 34,670 0.09% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $2,198,385 34,382 0.09% Shares
RTW INVESTMENTS, LP $2,194,200 30,000 0.09% Shares
Squadron Capital Management LLC $2,194,200 30,000 0.09% Call option
VICTORY CAPITAL MANAGEMENT INC $2,129,618 29,117 0.08% Shares
TUDOR INVESTMENT CORP ET AL $2,096,412 28,663 0.08% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $2,031,171 27,771 0.08% Shares
Y-Intercept (Hong Kong) Ltd $1,966,588 26,888 0.08% Shares
Rafferty Asset Management, LLC $1,943,037 26,566 0.08% Shares
Campbell & CO Investment Adviser LLC $1,870,044 25,568 0.07% Shares
BlackRock, Inc. $1,617,491 22,115 0.06% Shares
TD Asset Management Inc $1,579,824 21,600 0.06% Shares
Engineers Gate Manager LP $1,430,033 19,552 0.06% Shares
DLD Asset Management, LP $1,330,238 18,200 0.05% Put option
CITADEL ADVISORS LLC $1,258,008 17,200 0.05% Put option
MetLife Investment Management, LLC $1,213,246 16,588 0.05% Shares
CITADEL ADVISORS LLC $1,199,203 16,396 0.05% Shares
VANGUARD ASSET MANAGEMENT, Ltd $1,178,359 16,111 0.05% Shares
CITADEL ADVISORS LLC $1,155,612 15,800 0.05% Call option
STATE OF WISCONSIN INVESTMENT BOARD $1,128,477 15,429 0.04% Shares
Man Group plc $1,091,615 14,925 0.04% Shares
HighVista Strategies LLC $1,039,978 14,219 0.04% Shares

Company insiders 30 insiders · 12 officers · 16 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
John D Quisel Chief Executive Officer Aug. 17, 2026 M 226,064 0 14 $-12,028,932
Jason Patrick Meyenburg Chief Executive Officer Jan. 3, 2022 A 13,000 0 0 $0
Jean M. Franchi Chief Financial Officer April 14, 2026 S 64,333 0 6 $-1,204,945
Joanne Bryce Chief Financial Officer Jan. 10, 2024 A 23,665 0 0 $0
Brian Piekos CFO May 31, 2022 A 17,615 0 0 $0
William Jacob Savage Chief Medical Officer April 13, 2026 S 79,480 0 8 $-2,265,589
Pamela Stephenson Chief Commercial Officer Feb. 17, 2026 S 80,998 0 1 $-347,679
Brian Richard Macdonald Chief Innovation Officer June 30, 2023 S 12,276 0 0 $0
Walter Strapps Chief Scientific Officer April 29, 2021 A 0 0 $0
Samuel B. Barone Chief Medical Officer April 12, 2021 A 0 0 $0
Marc Uknis Chief Medical Officer Feb. 5, 2021 A 0 0 $0
Scott Lauder Chief Technology Officer Feb. 5, 2021 A 0 0 $0
Donald William Nicholson Director June 18, 2026 A 0 0 $0
William Richard White Director June 18, 2026 A 0 0 0 $0
Mark Chin Director June 18, 2026 A 0 0 $0
Nadim Ahmed Director June 18, 2026 A 0 0 $0
Kevin Bitterman Director June 18, 2026 A 14,161 0 19 $-16,858,638
Liam Ratcliffe Director June 18, 2026 A 0 0 $0
Georges Gemayel Director June 18, 2026 A 0 0 $0
Mona Ashiya Director June 11, 2025 A 186,541 0 0 $0
Jay T. Backstrom Director Dec. 29, 2022 A 0 0 $0
Tuyen Ong Director Oct. 4, 2021 A 0 0 $0
James B. Tananbaum Director Oct. 4, 2021 A 0 0 $0
Jason P Rhodes Director Oct. 4, 2021 A 0 0 $0
GORDON CARL L Director Oct. 4, 2021 A 0 0 $0
David Charles Lubner Director March 12, 2021 A 0 0 $0
Novo Holdings A/S 10% owner June 28, 2023 S 1,090,772 0 0 $0
Jonathan Yen-Wen Yu Aug. 12, 2026 M 54,324 0 11 $-4,833,128
Rahul Khara Aug. 6, 2026 M 52,324 0 11 $-1,874,683
Precillia Redmond Feb. 5, 2021 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 6 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Atlas Venture Fund X, L.P., ATLAS VENTURE ASSOCIATES X, L.P., Atlas Venture Associates X, LLC, Atlas Venture Fund XII, L.P., Atlas Venture Associates XII, L.P., Atlas Venture Associates XII, LLC, Atlas Venture Opportunity Fund I, L.P., Atlas Venture Associates Opportunity I, L.P., Atlas Venture Associates Opportunity I, LLC, Atlas Venture Opportunity Fund II, L.P., Atlas Venture Associates Opportunity II, LP, Atlas Venture Associates Opportunity II, LLC ×6 filings Dec. 17, 2025 2.20% Amendment SEC
AI DMI LLC, Access Industries Holdings LLC, Access Industries Management, LLC, Len Blavatnik ×7 filings Oct. 22, 2025 8.00% Amendment M&A / sale SEC
ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP VI LLC, OrbiMed Capital GP VIII LLC, OrbiMed Genesis GP LLC ×6 filings March 12, 2025 4.50% Amendment SEC
Adage Capital Partners, L.P., Adage Capital Partners GP, L.L.C., Adage Capital Advisors, L.L.C., Robert Atchinson, Phillip Gross ×3 filings Feb. 16, 2023 Initial filing SEC
Lightstone Ventures, L.P., Lightstone Ventures (A), L.P., LSV Associates, LLC, Lightstone Singapore, L.P., Lightstone Singapore Associates, LLC, Michael A. Carusi, Jean M. George, Henry A. Plain, Jr. ×2 filings Feb. 14, 2023 Initial filing M&A / sale SEC
FS Development Holdings, LLC, Foresite Capital Fund V, L.P., Foresite Capital Management V, LLC, Foresite Capital Opportunity Fund V, L.P., Foresite Capital Opportunity Management V, LLC, James Tananbaum ×3 filings Jan. 5, 2023 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 46 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
SBIO · ALPS ETF Trust 1.69% 39,334 NS May 31, 2026 N-PORT
FMED · Fidelity Covington Trust 1.18% 6,926 NS May 31, 2026 N-PORT
PTH · Invesco Exchange-Traded Fund Trust 0.86% 27,470 SH Aug. 8, 2026 Daily
LABU · Direxion Shares ETF Trust 0.74% 57,978 NS April 30, 2026 N-PORT
BBC · ETFis Series Trust I 0.53% 3,004 NS April 30, 2026 N-PORT
JDOC · J.P. Morgan Exchange-Traded Fund Tr… 0.38% 636 NS April 30, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.20% 2,080 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.16% 202,771 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.13% 254,812 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.13% 1,411 NS May 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.12% 30,333 SH Aug. 8, 2026 Daily
FFSM · FIDELITY COVINGTON TRUST 0.10% 19,972 NS April 30, 2026 N-PORT
ESSC · Strategy Shares 0.09% 356 NS April 30, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.09% 10,028 NS April 30, 2026 N-PORT
ISCG · iShares Trust 0.09% 11,028 SH Aug. 8, 2026 Daily
BKSE · BNY Mellon ETF Trust 0.08% 986 NS April 30, 2026 N-PORT
IWM · iShares Trust 0.07% 724,632 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.06% 162,749 SH Aug. 8, 2026 Daily
ESML · iShares Trust 0.06% 20,807 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.06% 11,910 NS April 30, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.05% 112,189 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.05% 1,293 NS May 31, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.05% 152,195 NS May 31, 2026 N-PORT
ISCB · iShares Trust 0.04% 1,550 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.04% 11,895 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.03% 366,845 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.03% 74,680 SH Aug. 8, 2026 Daily
UWM · ProShares Trust 0.03% 1,011 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.03% 11,162 NS April 30, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 8,781 SH Aug. 8, 2026 Daily
WSML · iShares Trust 0.02% 1,824 SH Aug. 8, 2026 Daily
URTY · ProShares Trust 0.02% 1,021 NS May 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.01% 4,076 NS April 30, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.01% 60,244 NS April 30, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 915 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.01% 26 NS May 31, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.01% 11,918 NS May 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 7,752 NS April 30, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 12,978 NS April 30, 2026 N-PORT
ITOT · iShares Trust 0.00% 49,447 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 8,370 SH Aug. 8, 2026 Daily
SCHB · SCHWAB STRATEGIC TRUST 0.00% 18,441 NS May 31, 2026 N-PORT
TILT · FlexShares Trust 0.00% 318 NS April 30, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 971,123 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 2,280 SH Aug. 8, 2026 Daily
FTLS · First Trust Exchange-Traded Fund III -0.03% -10,643 NS April 30, 2026 N-PORT