your badges 52W Range $56–$100 20% of range Analyst Rating BUY 19 analysts Price Target $103 +60% upside P/E -10.7 ROE -31.3% Net Profit Margin ·

IRON Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $64.51
Market Cap (MRQ) $2.47B
P/E -10.7
EPS $-6.01
ROE -31.3%
52W Range $56–$100

IRON Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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Stock splits 1
Ex-date Split Type
Dec. 30, 2022 1-for-30 Reverse

10-Year Performance Revenue, net income, margins and EPS trends

06
EPS$-6.01
2021-12-31 → 2025-12-31
Free Cash Flow$-181M
2021-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend IRON 5Y avg Peer Median Verdict
P/E -10.75Y avg ≈-9.7 ≈-9.7 · ·
P/B (MRQ) 3.85Y avg ≈8.9 ≈8.9 4.6 Fair value
Price / FCF (TTM) -12.55Y avg ≈-25.4 ≈-25.4 · ·
Price / Cash Flow (TTM) -12.55Y avg ≈-25.5 ≈-25.5 · ·
Price / Tangible Book 3.35Y avg ≈3.6 ≈3.6 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -2.2%
Next Report Nov 04, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 6, 2026 $-1.54 $-1.78 13.6%
March 31, 2026 May 7, 2026 $-1.65 $-1.75 5.6%
Dec. 31, 2025 $-1.64 $-1.78 7.8%
Sept. 30, 2025 $-1.77 $-1.49 -18.6%
June 30, 2025 $-1.58 $-1.18 -33.6%
March 31, 2025 $-1.02 $-1.16 11.7%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 14
Metric Trend 202520242023202220212020
R&D Expense $171M$97M$69M$33M$25M$28M
SG&A Expense $65M$33M$22M$14M$6M$6M
Operating Expenses $236M$130M$91M$47M$31M$34M
Operating Income $-236M$-130M$-91M$-47M$-31M$-34M
Interest Expense ····$2M$7M
Other Non-op $45.0K$-2.0K$-2.0K$0$-5M·
Pretax Income $-212M$-109M$-76M$-47M··
Income Tax $361.0K$355.0K$99.0K$0··
Net Income $-212M$-109M$-76M$-47M$-36M$-41M
EPS (Basic) $-6.01$-3.96$-3.42$-45.05$-40.95·
EPS (Diluted) $-6.01$-3.96$-3.42$-45.05$-40.95·
Shares (Basic) 35,295,66327,606,02222,315,8771,039,490878,407·
Shares (Diluted) 35,295,66327,606,02222,315,8771,039,490878,407·
EBITDA $-236M$-130M$-91M$-47M$-69M·
Balance Sheet 22
Metric Trend 202520242023202220212020
Cash & Equivalents $91M$192M$360M$195M$88M$5M
Short-term Investments $700M$297M$0···
Prepaid Expense $13M$4M$5M$4M$2M$562.0K
Current Assets $804M$494M$366M$198M$90M$5M
PP&E (Net) $1M$751.0K$170.0K$168.0K$106.0K$294.0K
PP&E (Gross) ····$0$955.0K
Accum. Depreciation ·$401.0K$245.0K$145.0K$56.0K$661.0K
Other Non-current Assets $726.0K$838.0K$234.0K$116.0K$180.0K·
Total Assets $807M$497M$368M$200M$92M$8M
Accounts Payable $9M$8M$13M$16M$3M$2M
Accrued Liabilities $16M$8M$6M$6M$4M$492.6K
Current Liabilities $37M$23M$21M$23M$13M$25M
Capital Leases $1M$2M$1M$1M$1M·
Total Liabilities $67M$53M$23M$24M$15M$30M
Long-term Debt $29M$28M$0··$14M
Common Stock $4.0K$3.0K$2.0K$2.0K$0$2.0K
Paid-in Capital $1.25B$741M$534M$289M$1M$91M
Retained Earnings $-510M$-298M$-189M$-112M$-65M$-113M
AOCI $965.0K$289.0K$0···
Stockholders' Equity $740M$444M$345M$177M$-64M$-29M
Liabilities + Equity $807M$497M$368M$200M$92M$8M
Shares Outstanding 37,890,61629,865,03024,360,23317,403,315909,41815,565,380
Cash Flow 15
Metric Trend 202520242023202220212020
D&A $281.0K$156.0K$100.0K$89.0K$32.0K·
Stock-based Comp $34M$17M$6M$2M$507.0K$983.0K
Deferred Tax $0·····
Other Non-cash $-3M$-2M$-3M$2M··
Operating Cash Flow $-180M$-94M$-73M$-42M$-28M$-33M
CapEx $933.0K$505.0K$89.0K$151.0K$68.0K$22.0K
Investing Cash Flow $-394M$-292M$-89.0K$-151.0K$-68.0K$-22.0K
Debt Issued $0$29M$0···
Net Debt Issued $0$29M····
Stock Issued ··$0$54M$0$20M
Net Stock Activity ··$0$54M$0·
Financing Cash Flow $473M$218M$239M$149M$90M$34M
Net Change in Cash $-101M$-168M$166M$107M$62M$2M
Taxes Paid $349.0K$300.0K$100.0K$0$0·
Free Cash Flow $-181M$-94M$-74M$-42M$-60M·
Profitability 3
Metric Trend 202520242023202220212020
ROA -32.6%-25.3%-26.9%-32.0%-96.6%·
ROE -31.3%-24.0%-21.7%-120.0%-54.1%·
ROIC -32.0%-29.3%-26.4%···
Liquidity & Solvency 3
Metric Trend 202520242023202220212020
Current Ratio 21.921.217.18.89.42.2
Quick Ratio 21.621.016.88.69.22.0
Interest Coverage ····-32.0·
Per Share 4
Metric Trend 202520242023202220212020
Book Value / Share $19.53$14.85$14.17$10.15$2.89·
Cash Flow / Share $-5.11$-3.40$-3.29$-40.65··
Cash / Share $2.41$6.44$14.79$11.18$3.16·
EPS (TTM) $-6.01$-3.96$-3.42$-45.05$-40.95·
Valuation (TTM) 8
Metric Trend 202520242023202220212020
Net Income TTM $-212M$-109M$-76M$-47M$-36M$-41M
Market Cap $3.01B$1.89B$1.41B$346M$3.77B·
P/E -13.2-16.0-16.9-0.4-2.1·
P/B 4.14.34.12.030.2·
P / Tangible Book 4.14.34.12.0··
P / Cash Flow -16.7-20.2-19.2-8.2-63.2·
P / FCF -16.6-20.1-19.1-8.2-63.1·
Earnings Yield -7.6%-6.2%-5.9%-226.5%-46.9%·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-212M $-109M $-76M $-47M $-36M
Diluted EPS $-6.01 $-3.96 $-3.42 $-45.05 $-40.95

Institutional owners (13F) 235 filers · $3.1B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 235
Value held $3.1B
New positions 44
Exited positions 22
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
44 (-11 vs prior Q) 22 (-15 vs prior Q) 77 (-5 vs prior Q) 66 (+24 vs prior Q) +795K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FMR LLC $357,981,753 4,894,473 11.37% Shares
BlackRock, Inc. $180,502,133 2,467,899 5.73% Shares
RA CAPITAL MANAGEMENT, L.P. $179,209,164 2,450,221 5.69% Shares
VANGUARD GROUP INC $140,371,470 1,767,680 4.46% Shares
JPMORGAN CHASE & CO $139,868,053 1,875,795 4.44% Shares
WELLINGTON MANAGEMENT GROUP LLP $127,362,413 1,741,351 4.05% Shares
STATE STREET CORP $120,595,865 1,648,836 3.83% Shares
Vestal Point Capital, LP $113,367,000 1,550,000 3.60% Shares
Atlas Venture Life Science Advisors, LLC $110,724,818 1,513,875 3.52% Shares
VANGUARD CAPITAL MANAGEMENT LLC $100,130,635 1,369,027 3.18% Shares
Frazier Life Sciences Management, L.P. $99,093,875 1,354,852 3.15% Shares
TCG Crossover Management, LLC $98,143,787 1,341,862 3.12% Shares
BVF INC/IL $84,375,182 1,153,612 2.68% Shares
Woodline Partners LP $70,088,672 958,281 2.23% Shares
Siren, L.L.C. $64,977,649 888,401 2.06% Shares
Logos Global Management LP $63,997,500 875,000 2.03% Shares
Opaleye Management Inc. $62,534,700 855,000 1.99% Shares
GEODE CAPITAL MANAGEMENT, LLC $57,772,342 789,724 1.84% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $48,052,980 657,000 1.53% Shares
DIMENSIONAL FUND ADVISORS LP $41,622,451 569,018 1.32% Shares
Bellevue Group AG $40,958,400 560,000 1.30% Shares
Saturn V Capital Management LP $38,378,752 524,730 1.22% Shares
ARMISTICE CAPITAL, LLC $33,644,400 460,000 1.07% Shares
JENNISON ASSOCIATES LLC $32,146,492 439,520 1.02% Shares
Aberdeen Group plc $32,048,046 438,174 1.02% Shares
Palo Alto Investors LP $30,473,488 416,646 0.97% Shares
EVENTIDE ASSET MANAGEMENT, LLC $28,938,480 395,651 0.92% Shares
Pictet Asset Management Holding SA $28,186,328 385,375 0.90% Shares
Assenagon Asset Management S.A. $28,097,316 384,158 0.89% Shares
LOOMIS SAYLES & CO L P $27,929,533 381,864 0.89% Shares
Foresite Capital Management V, LLC $27,359,407 374,069 0.87% Shares
ORBIMED ADVISORS LLC $26,150,110 357,535 0.83% Shares
BAKER BROS. ADVISORS LP $25,573,913 349,657 0.81% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $20,620,872 281,937 0.66% Shares
Octagon Capital Advisors LP $19,747,800 270,000 0.63% Shares
NORTHERN TRUST CORP $19,381,368 264,990 0.62% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $18,824,919 257,382 0.60% Shares
Checkpoint Capital L.P. $17,562,743 240,125 0.56% Shares
VANGUARD FIDUCIARY TRUST CO $16,470,982 225,198 0.52% Shares
CITADEL ADVISORS LLC $15,308,787 209,308 0.49% Shares
Bank of New York Mellon Corp $14,973,763 204,727 0.48% Shares
BNP PARIBAS FINANCIAL MARKETS $13,508,592 184,695 0.43% Shares
Catalio Capital Management, LP $11,657,346 159,384 0.37% Shares
Caption Management, LLC $10,971,000 150,000 0.35% Call option
Sofinnova Investments, Inc. $10,695,920 146,239 0.34% Shares
Bain Capital Life Sciences Investors, LLC $10,329,855 141,234 0.33% Shares
TWO SIGMA INVESTMENTS, LP $10,001,895 136,750 0.32% Shares
BANK OF AMERICA CORP /DE/ $9,882,018 135,111 0.31% Shares
Alyeska Investment Group, L.P. $9,142,500 125,000 0.29% Shares
Ensign Peak Advisors, Inc $8,931,199 122,111 0.28% Shares

Show all 235 institutional owners →

Activists & 5%+ owners 6 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Atlas Venture Fund X, L.P., ATLAS VENTURE ASSOCIATES X, L.P., Atlas Venture Associates X, LLC, Atlas Venture Fund XII, L.P., Atlas Venture Associates XII, L.P., Atlas Venture Associates XII, LLC, Atlas Venture Opportunity Fund I, L.P., Atlas Venture Associates Opportunity I, L.P., Atlas Venture Associates Opportunity I, LLC, Atlas Venture Opportunity Fund II, L.P., Atlas Venture Associates Opportunity II, LP, Atlas Venture Associates Opportunity II, LLC ×6 filings Dec. 17, 2025 2.20% Amendment · SEC
AI DMI LLC, Access Industries Holdings LLC, Access Industries Management, LLC, Len Blavatnik ×7 filings Oct. 22, 2025 8.00% Amendment M&A / sale SEC
ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP VI LLC, OrbiMed Capital GP VIII LLC, OrbiMed Genesis GP LLC ×6 filings March 12, 2025 4.50% Amendment · SEC
Adage Capital Partners, L.P., Adage Capital Partners GP, L.L.C., Adage Capital Advisors, L.L.C., Robert Atchinson, Phillip Gross ×3 filings Feb. 16, 2023 · Initial filing · SEC
Lightstone Ventures, L.P., Lightstone Ventures (A), L.P., LSV Associates, LLC, Lightstone Singapore, L.P., Lightstone Singapore Associates, LLC, Michael A. Carusi, Jean M. George, Henry A. Plain, Jr. ×2 filings Feb. 14, 2023 · Initial filing M&A / sale SEC
FS Development Holdings, LLC, Foresite Capital Fund V, L.P., Foresite Capital Management V, LLC, Foresite Capital Opportunity Fund V, L.P., Foresite Capital Opportunity Management V, LLC, James Tananbaum ×3 filings Jan. 5, 2023 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 31 insiders · 13 officers · 16 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
John D Quisel Chief Executive Officer Sept. 15, 2026 M 262,064 0 14 $-12,028,932
Jason Patrick Meyenburg Chief Executive Officer Jan. 3, 2022 A 13,000 0 0 $0
Jean M. Franchi Chief Financial Officer April 14, 2026 S 64,333 0 6 $-1,204,945
Joanne Bryce Chief Financial Officer Jan. 10, 2024 A 23,665 0 0 $0
Brian Piekos CFO May 31, 2022 A 17,615 0 0 $0
Jonathan Yen-Wen Yu Chief Operating Officer Aug. 25, 2026 M 54,324 0 13 $-5,589,011
William Jacob Savage Chief Medical Officer April 13, 2026 S 79,480 0 8 $-2,265,589
Pamela Stephenson Chief Commercial Officer Feb. 17, 2026 S 80,998 0 1 $-347,679
Brian Richard Macdonald Chief Innovation Officer June 30, 2023 S 12,276 0 0 $0
Walter Strapps Chief Scientific Officer April 29, 2021 A · 0 0 $0
Samuel B. Barone Chief Medical Officer April 12, 2021 A · 0 0 $0
Marc Uknis Chief Medical Officer Feb. 5, 2021 A · 0 0 $0
Scott Lauder Chief Technology Officer Feb. 5, 2021 A · 0 0 $0
Kevin Bitterman Director Sept. 11, 2026 M 0 0 62 $-37,690,863
Donald William Nicholson Director June 18, 2026 A · 0 0 $0
William Richard White Director June 18, 2026 A 0 0 0 $0
Mark Chin Director June 18, 2026 A · 0 0 $0
Nadim Ahmed Director June 18, 2026 A · 0 0 $0
Liam Ratcliffe Director June 18, 2026 A · 0 0 $0
Georges Gemayel Director June 18, 2026 A · 0 0 $0
Mona Ashiya Director June 11, 2025 A 186,541 0 0 $0
Jay T. Backstrom Director Dec. 29, 2022 A · 0 0 $0
Tuyen Ong Director Oct. 4, 2021 A · 0 0 $0
James B. Tananbaum Director Oct. 4, 2021 A · 0 0 $0
Jason P Rhodes Director Oct. 4, 2021 A · 0 0 $0
GORDON CARL L Director Oct. 4, 2021 A · 0 0 $0
David Charles Lubner Director March 12, 2021 A · 0 0 $0
Novo Holdings A/S 10% owner June 28, 2023 S 1,090,772 0 0 $0
Leonard Braden Michael 10% owner Oct. 26, 2022 S 247,500 0 0 $0
Rahul Khara · Aug. 6, 2026 M 52,324 0 11 $-1,874,683
Precillia Redmond · Feb. 5, 2021 A · 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 34 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBC · ETFis Series Trust I 0.76% 4,571 NS July 31, 2026 N-PORT
JDOC · J.P. Morgan Exchange-Traded Fund Tr… 0.51% 600 NS July 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.51% 32,477 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.16% 2,728 SH Oct. 2, 2026 Daily
IBB · iShares Trust 0.15% 211,840 SH Sept. 11, 2026 Daily
PWS · Pacer Funds Trust 0.14% 444 NS July 31, 2026 N-PORT
IWO · iShares Trust 0.14% 264,829 SH Sept. 11, 2026 Daily
FFSM · FIDELITY COVINGTON TRUST 0.12% 23,639 NS July 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.12% 30,333 SH Aug. 19, 2026 Daily
ESSC · Strategy Shares 0.11% 511 NS July 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.11% 9,517 NS July 31, 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0.09% 1,038 NS July 31, 2026 N-PORT
ISCG · iShares Trust 0.09% 11,064 SH Sept. 11, 2026 Daily
RSSL · Global X Funds 0.07% 13,544 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.07% 726,106 SH Sept. 11, 2026 Daily
DFAS · Dimensional ETF Trust 0.06% 119,817 NS July 31, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.06% 162,749 SH Aug. 19, 2026 Daily
ESML · iShares Trust 0.06% 20,861 SH Sept. 11, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.04% 11,895 SH Aug. 19, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.03% 366,845 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.03% 74,680 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.03% 11,949 NS July 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.02% 9,360 SH Oct. 2, 2026 Daily
WSML · iShares Trust 0.02% 1,429 SH Sept. 11, 2026 Daily
DFAC · Dimensional ETF Trust 0.01% 83,295 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.01% 4,161 NS July 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.01% 8,580 NS July 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 49,443 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 8,460 SH Sept. 11, 2026 Daily
DFUS · Dimensional ETF Trust 0.00% 7,860 NS July 31, 2026 N-PORT
TILT · FlexShares Trust 0.00% 334 NS July 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 971,123 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 2,280 SH Aug. 19, 2026 Daily
ISCB · iShares Trust · 1,550 SH Sept. 11, 2026 Daily

IRON Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 19 analysts BUY
Median target $100.00 +55.0%
7 36.8% Strong Buy
11 57.9% Buy
1 5.3% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

12 analysts · 2026-10-03

Mean target $103.17 +59.9%

← Below all targets Current price $64.51
Low$83.00 Mean$103.17 High$128.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
IRON $3.01B -13.2 · · -31.3% ·
DYN $3.23B -5.6 · · -57.8% ·
CLDX $1.81B -7.0 -78.0% -16748.0% -43.8% ·
BEAM $2.82B -34.2 120.0% -57.2% -7.0% ·
NRIX $1.80B -5.8 53.9% -314.9% -53.6% ·
IMNM $2.43B -8.8 -23.2% -3060.0% -47.0% ·
SLS $577M -15.1 · · -55.4% ·
VRDN $3.17B -7.7 23359.9% -483.6% -55.4% ·
ADMA $4.34B 30.4 19.6% 28.8% 33.6% 57.4%

Latest News Recent headlines mentioning this company

23
XPENG Q4 Earnings Call Highlights Yahoo Finance · 6 months, 1 week ago

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Jul 30, 2026