IMNM Immunome, Inc. - Common Stock
$28.96
Price · Aug 19, 2026
Fundamentals as of Aug 11, 2026
52W Range
$9–$30
97% of range
Analyst Rating
BUY
20 analysts
Price Target
$36
+25% upside
P/E (TTM)
-11.9
ROE
-47.0%
Net Profit Margin
-3060.0%
IMNM Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$28.96
Market Cap
$3.28B
P/E (TTM)
-11.9
EPS (TTM)
$-2.43
Revenue (TTM)
$7M
Div Yield
—
ROE
-47.0%
Debt/Equity
—
52W Range
$9 – $30
IMNM Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$7M
2023-12-31
→
2025-12-31
EPS
$-2.43
2020-12-31
→
2025-12-31
Free Cash Flow
$-201M
2020-12-31
→
2025-12-31
Margins
-3060.0%
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
IMNM
Peer Median
P/E (TTM)
-11.9
—
P/S (TTM)
472.0
18.3
P/B
5.2
3.3
Price / FCF
-16.3
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
IMNM
Peer Median
Operating Margin
-3228.8%
—
Net Profit Margin
-3060.0%
-180.4%
ROA
-46.0%
-36.2%
ROE
-47.0%
-43.7%
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
IMNM
Peer Median
Current Ratio
14.7
9.7
Quick Ratio
14.5
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
IMNM
Peer Median
Revenue YoY
-23.2%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
IMNM
Peer Median
IMNM Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
20 analysts
- Strong Buy 5 25.0%
- Buy 14 70.0%
- Hold 1 5.0%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
13 analysts · 2026-08-18
Median
$36.00
← Below all targets
$28.96
Low
$30.00
High
$40.00
Median target
$36.00
+24.3%
Mean target
$36.31
+25.4%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.02%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.48 | $-0.57 | 0.09% |
| Dec. 31, 2025 | $-0.76 | $-0.61 | -0.15% |
| Sept. 30, 2025 | $-0.65 | $-0.59 | -0.06% |
| June 30, 2025 | $-0.50 | $-0.54 | 0.04% |
| March 31, 2025 | $-0.52 | $-0.69 | 0.17% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| IMNM | $2.43B | -8.8 | -23.2% | -3060.0% | -47.0% | — |
| IDYA | $3.04B | -27.0 | 3024.4% | -52.0% | -11.5% | — |
| CLDX | $1.81B | -7.0 | -78.0% | -16748.0% | -43.8% | — |
| GRAL | $3.45B | -7.7 | 17.2% | -277.5% | -16.7% | — |
| ARQT | $3.58B | -223.4 | 91.3% | -4.3% | -9.8% | — |
| IOVA | $1.12B | -2.5 | 60.6% | -148.4% | -56.0% | — |
| IRON | $3.01B | -13.2 | — | — | -31.3% | — |
| NRIX | $1.80B | -5.8 | 53.9% | -314.9% | -53.6% | — |
| BEAM | $2.82B | -34.2 | 120.0% | -57.2% | -7.0% | — |
| SLS | $577M | -15.1 | — | — | -55.4% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 12
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $7M | $9M | $14M | |
| R&D Expense | $177M | $130M | $23M | |
| SG&A Expense | $44M | $33M | $20M | |
| Operating Expenses | $231M | $315M | $124M | |
| Operating Income | $-224M | $-306M | $-110M | |
| Income Tax | $0 | $0 | $0 | |
| Net Income | $-212M | $-293M | $-107M | |
| EPS (Basic) | $-2.43 | $-5.00 | $-5.38 | |
| EPS (Diluted) | $-2.43 | $-5.00 | $-5.38 | |
| Shares (Basic) | 87,350,956 | 58,639,441 | 19,843,651 | |
| Shares (Diluted) | 87,350,956 | 58,639,441 | 19,843,651 | |
| EBITDA | $-222M | $-304M | $-109M |
Balance Sheet 19
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $653M | $143M | $99M | |
| Prepaid Expense | $7M | $4M | $7M | |
| Current Assets | $661M | $221M | $145M | |
| PP&E (Net) | $15M | $10M | $2M | |
| Other Non-current Assets | $5M | $4M | $100.0K | |
| Total Assets | $683M | $240M | $149M | |
| Accounts Payable | $3M | $14M | $3M | |
| Current Liabilities | $45M | $54M | $22M | |
| Capital Leases | $4M | $5M | $1M | |
| Deferred Tax | $801.0K | $1M | $378.0K | |
| Other Non-current Liabilities | · | · | $1M | |
| Total Liabilities | $49M | $59M | $29M | |
| Common Stock | $11.0K | $6.0K | $4.0K | |
| Paid-in Capital | $1.36B | $697M | $343M | |
| Retained Earnings | $-728M | $-516M | $-223M | |
| AOCI | $0 | $57.0K | $22.0K | |
| Stockholders' Equity | $634M | $181M | $120M | |
| Liabilities + Equity | $683M | $240M | $149M | |
| Shares Outstanding | 113,133,199 | 64,460,829 | 43,251,778 |
Cash Flow 11
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| D&A | $2M | $2M | $457.0K | |
| Stock-based Comp | $26M | $16M | $6M | |
| Other Non-cash | $-7M | $165M | $93M | |
| Operating Cash Flow | $-191M | $-111M | $-8M | |
| CapEx | $10M | $7M | $831.0K | |
| Investing Cash Flow | $61M | $-85M | $-30M | |
| Stock Issued | $46M | $20M | $34.0K | |
| Net Stock Activity | $46M | $20M | $34.0K | |
| Financing Cash Flow | $640M | $241M | $116M | |
| Net Change in Cash | $510M | $45M | $78M | |
| Free Cash Flow | $-201M | $-118M | $-8M |
Profitability 5
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -3228.8% | -3382.4% | -781.4% | |
| Net Margin | -3060.0% | -3240.4% | -761.9% | |
| EBITDA Margin | -3193.3% | -3365.0% | -778.1% | |
| ROA | -46.0% | -150.7% | -123.8% | |
| ROE | -47.0% | -147.9% | -169.6% |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 14.7 | 4.1 | 6.6 | |
| Quick Ratio | 14.5 | 2.6 | 4.5 |
Efficiency 1
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.2 |
Growth Rates 1
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | -23.2% | -35.5% | · |
Valuation (TTM) 10
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $7M | $9M | $14M | |
| Net Income TTM | $-212M | $-293M | $-107M | |
| Market Cap | $2.43B | $685M | $463M | |
| P/E | -8.8 | -2.1 | -2.0 | |
| P/S | 350.1 | 75.7 | 33.0 | |
| P/B | 3.8 | 3.8 | 3.9 | |
| P / Tangible Book | 3.8 | 3.8 | 3.9 | |
| P / Cash Flow | -12.7 | -6.2 | -61.2 | |
| P / FCF | -12.1 | -5.8 | -55.1 | |
| Earnings Yield | -11.3% | -47.1% | -50.3% |
Income Statement 11
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $4M | $3M | $3M | $3M | $2M | $1M | $4M | $4M | $4M | $2M | |
| R&D Expense | $60M | $46M | $51M | $49M | $40M | $37M | $48M | $37M | $29M | $15M | $10M | $4M | $6M | $4M | |
| SG&A Expense | $18M | $13M | $12M | $11M | $10M | $11M | $10M | $10M | $7M | $6M | $8M | $4M | $4M | $3M | |
| Operating Expenses | $78M | $59M | $73M | $60M | $50M | $48M | $86M | $53M | $42M | $133M | $98M | $8M | $10M | $7M | |
| Operating Income | $-78M | $-59M | $-73M | $-60M | $-46M | $-45M | $-83M | $-51M | $-40M | $-132M | $-95M | $-5M | $-6M | $-4M | |
| Net Income | $-73M | $-54M | $-70M | $-57M | $-43M | $-42M | $-80M | $-47M | $-36M | $-129M | $-93M | $-4M | $-6M | $-4M | |
| EPS (Basic) | $-0.65 | $-0.48 | $-0.76 | $-0.65 | $-0.50 | $-0.52 | $-1.11 | $-0.78 | $-0.60 | $-2.51 | $-4.21 | $-0.36 | $-0.46 | $-0.35 | |
| EPS (Diluted) | $-0.65 | $-0.48 | $-0.76 | $-0.65 | $-0.50 | $-0.52 | $-1.11 | $-0.78 | $-0.60 | $-2.51 | $-4.21 | $-0.36 | $-0.46 | $-0.35 | |
| Shares (Basic) | 113,272,931 | 113,136,836 | -167,028,008 | 87,957,868 | 87,010,742 | 79,410,354 | -113,046,972 | 60,205,327 | 59,936,703 | 51,544,383 | -16,738,963 | 12,202,335 | 12,197,801 | 12,182,478 | |
| Shares (Diluted) | 113,272,931 | 113,136,836 | -167,028,008 | 87,957,868 | 87,010,742 | 79,410,354 | -113,046,972 | 60,205,327 | 59,936,703 | 51,544,383 | -16,738,963 | 12,202,335 | 12,197,801 | 12,182,478 | |
| EBITDA | $-78M | $-59M | · | $-60M | $-46M | $-44M | · | $-51M | $-40M | $-132M | · | $-5M | $-6M | $-4M |
Balance Sheet 19
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $218M | $583M | $653M | $273M | $144M | $258M | $143M | $156M | $165M | $270M | $99M | $91M | $38M | $44M | |
| Prepaid Expense | $18M | $12M | $7M | $7M | $9M | $6M | $4M | $4M | $6M | $4M | $7M | $773.0K | $1M | $2M | |
| Current Assets | $538M | $594M | $661M | $280M | $277M | $323M | $221M | $244M | $284M | $313M | $145M | $91M | $40M | $47M | |
| PP&E (Net) | $17M | $17M | $15M | $12M | $11M | $11M | $10M | $7M | $6M | $4M | $2M | $1M | $1M | $916.0K | |
| Other Non-current Assets | $5M | $5M | $5M | $5M | $4M | $4M | $4M | $3M | $3M | $568.0K | $100.0K | · | · | · | |
| Total Assets | $565M | $620M | $683M | $299M | $296M | $343M | $240M | $257M | $296M | $320M | $149M | $93M | $41M | $48M | |
| Accounts Payable | $6M | $6M | $3M | $6M | $5M | $9M | $14M | $4M | $7M | $7M | $3M | $3M | $4M | $3M | |
| Current Liabilities | $36M | $27M | $45M | $31M | $23M | $31M | $54M | $40M | $40M | $31M | $22M | $23M | $26M | $25M | |
| Capital Leases | $5M | $4M | $4M | $4M | $4M | $5M | $5M | $2M | $2M | $1M | $1M | · | · | · | |
| Deferred Tax | · | · | $801.0K | · | · | · | $1M | · | · | · | $378.0K | · | · | · | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | · | $122.0K | · | · | |
| Total Liabilities | $40M | $31M | $49M | $35M | $27M | $36M | $59M | $42M | $42M | $34M | $29M | $87M | $32M | $34M | |
| Common Stock | $11.0K | $11.0K | $11.0K | $9.0K | $9.0K | $9.0K | $6.0K | $6.0K | $6.0K | $6.0K | $4.0K | $1.0K | $1.0K | $1.0K | |
| Paid-in Capital | $1.38B | $1.37B | $1.36B | $922M | $870M | $865M | $697M | $650M | $642M | $638M | $343M | $136M | $135M | $134M | |
| Retained Earnings | $-855M | $-782M | $-728M | $-658M | $-601M | $-557M | $-516M | $-436M | $-388M | $-352M | $-223M | $-130M | $-126M | $-120M | |
| AOCI | $-333.0K | · | $0 | $0 | $-24.0K | $-3.0K | $57.0K | $70.0K | $2.0K | $4.0K | $22.0K | · | · | · | |
| Stockholders' Equity | $525M | $589M | $634M | $264M | $269M | $307M | $181M | $215M | $254M | $286M | $120M | $6M | $9M | $14M | |
| Liabilities + Equity | $565M | $620M | $683M | $299M | $296M | $343M | $240M | $257M | $296M | $320M | $149M | $93M | $41M | $48M | |
| Shares Outstanding | 113,399,202 | 113,171,396 | 113,133,199 | 91,706,948 | 87,012,835 | 86,955,855 | 64,460,829 | 60,422,062 | 60,013,655 | 59,694,243 | 43,251,778 | 12,202,516 | 12,200,433 | 12,194,184 |
Cash Flow 11
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $957.0K | $603.0K | $629.0K | $589.0K | $637.0K | $611.0K | $450.0K | $411.0K | $549.0K | $157.0K | $151.0K | $111.0K | $101.0K | $94.0K | |
| Stock-based Comp | $9M | $8M | $8M | $7M | $5M | $6M | $5M | $5M | $3M | $2M | $3M | $1M | $1M | $1M | |
| Other Non-cash | · | $-13M | · | · | · | $-18M | · | · | · | $116M | · | · | · | $27M | |
| Operating Cash Flow | $-62M | $-59M | $-48M | $-41M | $-49M | $-53M | $-42M | $-34M | $-23M | $-11M | $-17M | $-9M | $-6M | $24M | |
| CapEx | $2M | $3M | $4M | $1M | $905.0K | $4M | $1M | $2M | $2M | $2M | $349.0K | $36.0K | $340.0K | $106.0K | |
| Investing Cash Flow | $-304M | $-12M | $-4M | $124M | $-64M | $5M | $10M | $24M | $-82M | $-37M | $-30M | $-36.0K | $-340.0K | $-106.0K | |
| Stock Issued | · | · | $0 | · | · | · | $20M | · | · | · | $0 | $0 | $0 | $34.0K | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | · | · | $34.0K | |
| Financing Cash Flow | $1M | $-135.0K | $433M | $45M | $-55.0K | $162M | $20M | $305.0K | $694.0K | $219M | $55M | $61M | $0 | $34.0K | |
| Net Change in Cash | $-365M | $-71M | $381M | $129M | $-114M | $114M | $-12M | $-10M | $-104M | $171M | $8M | $52M | $-6M | $24M | |
| Free Cash Flow | · | $-62M | · | · | · | $-57M | · | · | · | $-13M | · | · | · | $24M |
Profitability 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | -1157.6% | -1525.5% | · | -1736.1% | -1692.4% | -12857.1% | · | -130.0% | -135.4% | -189.1% | |
| Net Margin | · | · | · | · | -1080.9% | -1423.1% | · | -1618.6% | -1528.0% | -12584.3% | · | -121.9% | -130.4% | -180.6% | |
| EBITDA Margin | · | · | · | · | -1157.6% | -1504.6% | · | -1736.1% | -1692.4% | -12841.8% | · | -130.0% | -135.4% | -185.2% | |
| ROA | -17.0% | -11.2% | · | -20.7% | -14.6% | -12.6% | · | -26.9% | -21.4% | -70.4% | · | -7.0% | -13.8% | -8.9% | |
| ROE | -18.4% | -12.0% | · | -24.0% | -16.6% | -14.1% | · | -42.6% | -27.5% | -86.5% | · | -29.8% | -28.1% | -16.5% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 15.1 | 21.7 | · | 8.9 | 12.1 | 10.5 | · | 6.2 | 7.1 | 10.2 | · | 4.0 | 1.5 | 1.9 | |
| Quick Ratio | 6.1 | 21.3 | · | 8.7 | 6.3 | 8.4 | · | 3.9 | 4.1 | 8.8 | · | 3.9 | 1.5 | 1.8 |
Efficiency 1
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.1 | 0.1 | 0.0 |
Valuation (TTM) 10
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $4M | $7M | · | $10M | $12M | $9M | · | $10M | $11M | $11M | · | · | · | · | |
| Net Income TTM | $-228M | $-196M | · | $-190M | $-168M | $-254M | · | $-217M | $-176M | $-144M | · | $-23M | $-27M | $-33M | |
| Market Cap | $2.40B | $2.48B | · | $1.07B | $809M | $585M | · | $883M | $726M | $1.47B | · | $102M | $97M | $61M | |
| P/E | -9.3 | -10.2 | · | -4.8 | -3.9 | -1.5 | · | -3.4 | -3.1 | -6.7 | · | -4.3 | -3.4 | -1.8 | |
| P/S | 598.5 | 356.6 | · | 109.0 | 66.2 | 63.4 | · | 89.5 | 64.7 | 131.3 | · | · | · | · | |
| P/B | 4.6 | 4.2 | · | 4.1 | 3.0 | 1.9 | · | 4.1 | 2.9 | 5.2 | · | 16.8 | 10.3 | 4.4 | |
| P / Tangible Book | 4.6 | 4.2 | · | 4.1 | 3.0 | 1.9 | · | 4.1 | 2.9 | 5.2 | · | 16.8 | 10.3 | 4.4 | |
| P / Cash Flow | · | -42.2 | · | · | · | -11.0 | · | · | · | -131.9 | · | · | · | 2.5 | |
| P / FCF | · | -40.2 | · | · | · | -10.3 | · | · | · | -110.5 | · | · | · | 2.5 | |
| Earnings Yield | -10.8% | -9.8% | · | -20.9% | -25.8% | -65.5% | · | -29.1% | -32.5% | -14.9% | · | -23.0% | -29.1% | -56.1% |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenue | $7M | $9M | $14M | — | — |
| Operating Margin % | -3228.8% | -3382.4% | -781.4% | -738020.0% | 252040.0% |
| Net Income | $-212M | $-293M | $-107M | $-37M | $-25M |
| Diluted EPS | $-2.43 | $-5.00 | $-5.38 | $-3.09 | $-2.14 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Current Ratio | 14.7 | 4.1 | 6.6 | 3.1 | 5.8 |
| Quick Ratio | 14.5 | 2.6 | 4.5 | 2.8 | 5.1 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | $-201M | $-118M | $-8M | $-29M | $-18M |
Latest News Recent headlines mentioning this company
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Institutional owners (13F) 218 filers · $1.5B total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 38 (-5 vs prior Q) | 25 (-3 vs prior Q) | 68 (-5 vs prior Q) | 60 (+13 vs prior Q) | +8.2M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| FMR LLC | $219,412,109 | 10,354,512 | 14.46% | Shares |
| STATE STREET CORP | $116,431,104 | 5,494,625 | 7.67% | Shares |
| Redmile Group, LLC | $104,076,592 | 4,911,590 | 6.86% | Shares |
| PRIMECAP MANAGEMENT CO/CA/ | $97,080,523 | 4,581,431 | 6.40% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $96,441,814 | 4,551,289 | 6.35% | Shares |
| Driehaus Capital Management LLC | $92,094,685 | 4,346,139 | 6.07% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $91,744,775 | 4,329,626 | 6.05% | Shares |
| ENAVATE SCIENCES GP, LLC | $76,576,401 | 3,613,799 | 5.05% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $50,056,190 | 2,361,709 | 3.30% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $42,740,421 | 2,017,009 | 2.82% | Shares |
| Sofinnova Investments, Inc. | $36,453,496 | 1,720,316 | 2.40% | Shares |
| READYSTATE ASSET MANAGEMENT LP | $34,027,326 | 1,605,820 | 2.24% | Shares |
| JPMORGAN CHASE & CO | $28,653,198 | 1,357,265 | 1.89% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $28,584,865 | 1,348,979 | 1.88% | Shares |
| GOLDMAN SACHS GROUP INC | $24,727,098 | 1,166,923 | 1.63% | Shares |
| Woodline Partners LP | $21,198,434 | 1,000,398 | 1.40% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $18,778,430 | 886,193 | 1.24% | Shares |
| MetLife Investment Management, LLC | $18,203,820 | 859,076 | 1.20% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $16,025,933 | 756,297 | 1.06% | Shares |
| Pivotal bioVenture Partners Investment Advisor LLC | $15,521,929 | 732,512 | 1.02% | Shares |
| TD Asset Management Inc | $15,241,374 | 719,272 | 1.00% | Shares |
| NAN FUNG TRINITY (HK) LTD | $15,141,378 | 714,553 | 1.00% | Shares |
| Candriam S.C.A. | $14,398,131 | 680,132 | 0.95% | Shares |
| Parkman Healthcare Partners LLC | $12,591,140 | 594,202 | 0.83% | Shares |
| BANK OF AMERICA CORP /DE/ | $12,311,114 | 580,987 | 0.81% | Shares |
| MARSHALL WACE, LLP | $9,803,490 | 462,647 | 0.65% | Shares |
| Qube Research & Technologies Ltd | $9,306,351 | 439,186 | 0.61% | Shares |
| ALERUS FINANCIAL NA | $8,124,691 | 383,421 | 0.54% | Shares |
| Granahan Investment Management, LLC | $8,021,305 | 378,542 | 0.53% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $7,623,738 | 359,780 | 0.50% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $7,446,187 | 351,401 | 0.49% | Shares |
| Rock Springs Capital Management LP | $7,367,043 | 347,666 | 0.49% | Shares |
| Atom Investors LP | $6,303,792 | 297,489 | 0.42% | Shares |
| KENNEDY CAPITAL MANAGEMENT LLC | $5,870,986 | 277,064 | 0.39% | Shares |
| FIRST TRUST ADVISORS LP | $5,569,219 | 262,823 | 0.37% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $5,320,851 | 251,102 | 0.35% | Shares |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $4,913,134 | 231,861 | 0.32% | Shares |
| CITADEL ADVISORS LLC | $4,748,234 | 224,079 | 0.31% | Shares |
| Burkehill Global Management, LP | $4,238,000 | 200,000 | 0.28% | Shares |
| Swiss National Bank | $3,848,104 | 181,600 | 0.25% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $3,663,603 | 172,893 | 0.24% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3,649,448 | 172,225 | 0.24% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3,388,281 | 159,900 | 0.22% | Call option |
| Atika Capital Management LLC | $3,247,092 | 153,237 | 0.21% | Shares |
| GILDER GAGNON HOWE & CO LLC | $3,226,495 | 152,265 | 0.21% | Shares |
| FEDERATED HERMES, INC. | $3,011,035 | 142,097 | 0.20% | Shares |
| ALLIANCEBERNSTEIN L.P. | $2,919,645 | 133,500 | 0.19% | Shares |
| CITIGROUP INC | $2,884,340 | 136,118 | 0.19% | Shares |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $2,870,000 | 135,451 | 0.19% | Shares |
| AMERIPRISE FINANCIAL INC | $2,816,279 | 132,906 | 0.19% | Shares |
| RHUMBLINE ADVISERS | $2,807,216 | 132,479 | 0.18% | Shares |
| Schonfeld Strategic Advisors LLC | $2,799,007 | 132,091 | 0.18% | Shares |
| XTX Topco Ltd | $2,683,671 | 126,648 | 0.18% | Shares |
| Sio Capital Management, LLC | $2,631,120 | 124,168 | 0.17% | Shares |
| Aristotle Atlantic Partners, LLC | $2,582,107 | 121,855 | 0.17% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2,437,280 | 111,444 | 0.16% | Shares |
| ALPS ADVISORS INC | $2,424,984 | 114,440 | 0.16% | Shares |
| TEMA ETFS LLC | $2,192,141 | 102,055 | 0.14% | Shares |
| Bank of New York Mellon Corp | $2,149,153 | 101,423 | 0.14% | Shares |
| AXA Investment Managers S.A. | $2,108,456 | 180,056 | 0.14% | Shares |
| JANE STREET GROUP, LLC | $1,981,265 | 93,500 | 0.13% | Call option |
| Trexquant Investment LP | $1,873,005 | 88,391 | 0.12% | Shares |
| BlackRock, Inc. | $1,790,428 | 84,494 | 0.12% | Shares |
| BIT Capital GmbH | $1,767,246 | 83,400 | 0.12% | Shares |
| Rafferty Asset Management, LLC | $1,762,372 | 83,170 | 0.12% | Shares |
| Neo Ivy Capital Management | $1,713,762 | 80,876 | 0.11% | Shares |
| Susquehanna Portfolio Strategies, LLC | $1,574,926 | 74,324 | 0.10% | Shares |
| Edgestream Partners, L.P. | $1,523,243 | 71,885 | 0.10% | Shares |
| VANGUARD ASSET MANAGEMENT, Ltd | $1,414,009 | 66,730 | 0.09% | Shares |
| Freestone Capital Holdings, LLC | $1,283,881 | 60,589 | 0.08% | Shares |
| CAPTRUST FINANCIAL ADVISORS | $1,272,375 | 60,046 | 0.08% | Shares |
| Ikarian Capital, LLC | $1,271,401 | 60,000 | 0.08% | Shares |
| SummitTX Capital, L.P. | $1,260,296 | 59,476 | 0.08% | Shares |
| CITADEL ADVISORS LLC | $1,229,020 | 58,000 | 0.08% | Call option |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $1,222,091 | 57,673 | 0.08% | Shares |
| BAKER BROS. ADVISORS LP | $1,171,934 | 55,306 | 0.08% | Shares |
| JANUS HENDERSON GROUP PLC | $1,155,878 | 52,816 | 0.08% | Shares |
| Erste Asset Management GmbH | $1,094,080 | 52,000 | 0.07% | Shares |
| Birchview Capital, LP | $1,059,500 | 50,000 | 0.07% | Shares |
| AlphaQuest LLC | $1,051,833 | 48,968 | 0.07% | Shares |
| Lido Advisors, LLC | $1,045,536 | 49,341 | 0.07% | Shares |
| Vanguard Global Advisers, LLC | $1,040,090 | 49,084 | 0.07% | Shares |
| VANGUARD GROUP INC | $1,023,329 | 47,641 | 0.07% | Shares |
| VICTORY CAPITAL MANAGEMENT INC | $1,007,034 | 47,524 | 0.07% | Shares |
| NISA INVESTMENT ADVISORS, LLC | $1,000,740 | 47,227 | 0.07% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $983,216 | 46,400 | 0.06% | Put option |
| STATE OF WISCONSIN INVESTMENT BOARD | $962,937 | 45,443 | 0.06% | Shares |
| Scharf Investments, LLC | $940,603 | 44,389 | 0.06% | Shares |
| Corient Private Wealth LP | $915,981 | 43,227 | 0.06% | Shares |
| PROFUND ADVISORS LLC | $903,436 | 42,635 | 0.06% | Shares |
| Invesco Ltd. | $892,586 | 42,123 | 0.06% | Shares |
| Magnus Financial Group LLC | $884,873 | 41,759 | 0.06% | Shares |
| Cerity Partners LLC | $838,700 | 39,580 | 0.06% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $784,030 | 37,000 | 0.05% | Shares |
| Palumbo Wealth Management LLC | $692,045 | 32,659 | 0.05% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $678,228 | 32,007 | 0.04% | Shares |
| Police & Firemen's Retirement System of New Jersey | $658,797 | 31,090 | 0.04% | Shares |
| INTECH INVESTMENT MANAGEMENT LLC | $645,447 | 30,460 | 0.04% | Shares |
| State of New Jersey Common Pension Fund D | $620,125 | 29,265 | 0.04% | Shares |
| Campbell & CO Investment Adviser LLC | $563,760 | 26,605 | 0.04% | Shares |
Company insiders 27 insiders · 13 officers · 13 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Clay B Siegall | President and CEO | July 23, 2026 A | 870,704 | 4 | 0 | $1,749,659 |
| Purnanand D Sarma | President and CEO | June 8, 2023 A | 10,500 | 0 | 0 | $0 |
| Max Rosett | Chief Financial Officer | July 23, 2026 A | 101,287 | 0 | 1 | $-1,093,800 |
| Corleen M. Roche | Chief Financial Officer | June 8, 2023 A | — | 0 | 0 | $0 |
| Richard F Fitzgerald | Chief Financial Officer | Oct. 1, 2020 A | — | 0 | 0 | $0 |
| Philip Tsai | Chief Technical Officer | July 23, 2026 A | 81,550 | 0 | 0 | $0 |
| Robert Lechleider | Chief Medical Officer | July 23, 2026 A | 69,805 | 0 | 5 | $-2,335,993 |
| Jack Higgins | Chief Scientific Officer | July 23, 2026 A | 60,250 | 0 | 0 | $0 |
| Sandra G. Stoneman | CHIEF LEGAL OFFICER & GC | July 23, 2026 A | 43,805 | 0 | 0 | $0 |
| Phil Noland Roberts | Chief Technology Officer | Dec. 13, 2023 A | — | 0 | 0 | $0 |
| Bruce Turner | Chief Strategy Officer | Oct. 2, 2023 P | 42,300 | 0 | 0 | $0 |
| Matthew K Robinson | Chief Technology Officer | June 8, 2023 A | — | 0 | 0 | $0 |
| Dennis H Giesing | Chief Development Officer | June 8, 2023 A | — | 0 | 0 | $0 |
| James P Boylan | Director | June 10, 2026 A | — | 0 | 0 | $0 |
| Sandra M Swain | Director | June 10, 2026 A | — | 0 | 0 | $0 |
| Philip Wagenheim | Director | June 10, 2026 A | 341,147 | 0 | 2 | $-1,335,626 |
| Carol Schafer | Director | June 10, 2026 A | — | 0 | 0 | $0 |
| Jean Jacques Bienaime | Director | June 10, 2026 A | 43,415 | 6 | 2 | $147,610 |
| Michael Rapp | Director | Oct. 2, 2023 A | 1,071,172 | 0 | 0 | $0 |
| Franklyn G Prendergast | Director | Oct. 2, 2023 A | 60,840 | 0 | 0 | $0 |
| Michael Lefenfeld | Director | June 8, 2023 A | 40,747 | 0 | 0 | $0 |
| Richard A Baron | Director | June 8, 2023 A | 2,343 | 0 | 0 | $0 |
| John L Lamattina | Director | June 8, 2023 A | 66,953 | 0 | 0 | $0 |
| Michael Widlitz | Director | May 28, 2021 A | 51,315 | 0 | 0 | $0 |
| Wistar I Morris III | 10% owner | Oct. 6, 2020 C | 38,464 | 0 | 0 | $0 |
| Isaac Barchas | — | Aug. 12, 2026 S | 92,211 | 0 | 10 | $-9,944,909 |
| Kinney Horn | — | Aug. 4, 2026 M | 0 | 0 | 2 | $-2,300,855 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 5 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Enavate Sciences GP, LLC, Immunome Aggregator, LP | Dec. 22, 2025 | 4.30% | Amendment | — | SEC |
| Immunome Aggregator, LP, Enavate Sciences GP, LLC | Feb. 4, 2025 | 6.00% | Amendment | — | SEC |
| Arsenal Bridge Venture II, LLC, Arsenal Bridge Venture II-B, LLC, Arsenal Bridge Advisors, LLC, RBP Catalyst Fund, L.P., Research Bridge Partners, Inc., Isaac Barchas, James Graham ×2 filings | Aug. 21, 2024 | — | Initial filing | — | SEC |
| Undisclosed reporting person | Oct. 12, 2023 | — | Initial filing | Passive investment | SEC |
| Morphimmune Inc. | July 7, 2023 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 42 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| CANC · Tema ETF Trust | 3.91% | 315,648 NS | May 31, 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0.87% | 14,102 NS | April 30, 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.74% | 168,145 NS | April 30, 2026 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0.69% | 3,351 NS | April 30, 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0.34% | 157,162 NS | April 30, 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0.30% | 7,075 NS | May 31, 2026 | N-PORT |
| IWO · iShares Trust | 0.17% | 955,843 SH | Aug. 8, 2026 | Daily |
| VFMO · VANGUARD WELLINGTON FUND | 0.14% | 127,656 SH | Aug. 8, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.13% | 113,000 SH | Aug. 8, 2026 | Daily |
| FYX · First Trust Exchange-Traded AlphaDE… | 0.12% | 63,318 NS | April 30, 2026 | N-PORT |
| IWM · iShares Trust | 0.09% | 2,689,690 SH | Aug. 8, 2026 | Daily |
| RSSL · Global X Funds | 0.07% | 44,221 NS | April 30, 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.07% | 606,588 SH | Aug. 8, 2026 | Daily |
| FAD · First Trust Exchange-Traded AlphaDE… | 0.07% | 14,653 NS | April 30, 2026 | N-PORT |
| ESML · iShares Trust | 0.06% | 68,747 SH | Aug. 8, 2026 | Daily |
| ITWO · ProShares Trust | 0.06% | 4,805 NS | May 31, 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0.05% | 496,351 NS | May 31, 2026 | N-PORT |
| ISCG · iShares Trust | 0.04% | 17,326 SH | Aug. 8, 2026 | Daily |
| GSSC · Goldman Sachs ETF Trust | 0.04% | 18,348 NS | May 31, 2026 | N-PORT |
| ISCB · iShares Trust | 0.04% | 4,411 SH | Aug. 8, 2026 | Daily |
| ISCV · iShares Trust | 0.03% | 9,397 SH | Aug. 8, 2026 | Daily |
| FHLC · FIDELITY COVINGTON TRUST | 0.03% | 42,979 NS | April 30, 2026 | N-PORT |
| UWM · ProShares Trust | 0.03% | 3,758 NS | May 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.03% | 1,223,884 SH | Aug. 8, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | 0.03% | 272,423 SH | Aug. 8, 2026 | Daily |
| URTY · ProShares Trust | 0.02% | 3,800 NS | May 31, 2026 | N-PORT |
| WSML · iShares Trust | 0.02% | 5,653 SH | Aug. 8, 2026 | Daily |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.01% | 3,920 NS | May 31, 2026 | N-PORT |
| HDG · ProShares Trust | 0.01% | 95 NS | May 31, 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.01% | 10,511 SH | Aug. 8, 2026 | Daily |
| ONEQ · Fidelity Commonwealth Trust | 0.01% | 30,872 NS | May 31, 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0.01% | 7,094 NS | May 31, 2026 | N-PORT |
| IWV · iShares Trust | 0.00% | 31,136 SH | Aug. 8, 2026 | Daily |
| ITOT · iShares Trust | 0.00% | 145,395 SH | Aug. 8, 2026 | Daily |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 61,158 NS | May 31, 2026 | N-PORT |
| TILT · FlexShares Trust | 0.00% | 2,618 NS | April 30, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.00% | 1,752 NS | April 30, 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0.00% | 6,695 NS | April 30, 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0.00% | 628 NS | April 30, 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0.00% | 1,576 NS | April 30, 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 3,225,694 SH | Aug. 8, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 8,523 SH | Aug. 8, 2026 | Daily |