SMMT Summit Therapeutics Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$12.97
Price · Aug 19, 2026
Fundamentals as of Jul 23, 2026

SMMT Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$12.97
Market Cap
$10.06B
P/E (TTM)
-9.0
EPS (TTM)
$-1.44
Revenue (TTM)
$0
Div Yield
ROE
-235.1%
Debt/Equity
52W Range
$12 – $30

SMMT Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $0
7-point trend, -100.0%
2019-01-31 2024-12-31
EPS $-1.44
8-point trend, -328.6%
2019-01-31 2025-12-31
Free Cash Flow $-324M
6-point trend, -566.7%
2020-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
SMMT
Peer Median
P/E (TTM)
5-point trend, -202.5%
-9.0
28.5
P/B
5-point trend, +550.0%
15.3
12.9
Price / FCF
5-point trend, -1058.3%
-31.1

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
SMMT
Peer Median
ROA
5-point trend, -121.6%
-181.9%
-28.4%
ROE
5-point trend, -146.2%
-235.1%
-49.2%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
SMMT
Peer Median
Current Ratio
5-point trend, +159.9%
9.9
5.0
Quick Ratio
5-point trend, +241.9%
9.8

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
SMMT
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
SMMT
Peer Median
EPS (Diluted)
5-point trend, -114.9%
$-1.44

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
SMMT
Peer Median

SMMT Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 24 analysts
  • Strong Buy 5 20.8%
  • Buy 11 45.8%
  • Hold 6 25.0%
  • Sell 1 4.2%
  • Strong Sell 1 4.2%

12-Month Price Target

13 analysts · 2026-08-17
Median target $33.52 +158.5%
Mean target $28.61 +120.6%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.08%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.28 $-0.28 0.00%
March 31, 2026 $-0.24 $-0.18 -0.06%
Dec. 31, 2025 $-0.29 $-0.07 -0.22%
Sept. 30, 2025 $-0.31 $-0.13 -0.18%
June 30, 2025 $-0.12 $-0.10 -0.02%
March 31, 2025 $-0.09 $-0.09 0.00%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
SMMT $13.56B -12.1 -235.1%
MDGL $13.30B -45.3 432.1% -30.1% -44.4%
HALO $7.93B 26.3 37.5% 22.7% 166.1%
CYTK $7.81B -9.7 376.6% -891.6% 152.7%
PRAX $7.43B -21.9 249.5% -47.3%
PTGX $5.47B -42.6 -89.4% -282.8% -20.3%
KYMR $6.33B -21.1 -16.7% -794.0% -24.4%
APGE $5.16B -17.9
KRYS $7.20B 36.0 33.9% 52.6% 18.1%
IONS $12.92B -33.2 -68.1%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for SMMT
Metric Trend 2025202420232022202120202019
Revenue 6-point trend, -100.0% · $0 $0 $705.0K $2M $860.0K $743.0K
R&D Expense 5-point trend, +49.4% · · $59M $52M $85M $53M $40M
SG&A Expense 7-point trend, +4836.2% $557M $60M $29M $27M $24M $19M $11M
Operating Expenses 7-point trend, +2042.2% $1.09B $226M $610M $87M $109M $73M $51M
Operating Income 6-point trend, -722.6% · $-226M $-610M $-72M $-86M $-53M $-27M
Interest Expense 4-point trend, +1412.4% · · · $4M $242.0K $255.0K $291.0K
Interest Income 4-point trend, +30160.0% · · · $2M $0 $4.0K $5.0K
Other Non-op 7-point trend, +96.7% $-53.0K $0 $-252.0K $304.0K $-39.0K $283.0K $-2M
Pretax Income 7-point trend, -3611.1% $-1.08B $-221M $-615M $-79M $-89M $-53M $-29M
Income Tax 6-point trend, -100.0% $0 $0 $0 · $0 $-213.0K $36.0K
Net Income 7-point trend, -3606.5% $-1.08B $-221M $-615M $-79M $-89M $-53M $-29M
EPS (Basic) 7-point trend, -61.8% $-1.44 $-0.31 $-0.99 $-0.41 $-0.67 $-0.76 $-0.89
EPS (Diluted) 7-point trend, -61.8% $-1.44 $-0.31 $-0.99 $-0.41 $-0.67 $-0.76 $-0.89
Shares (Basic) 7-point trend, +2177.6% 747,702,265 718,541,896 619,646,180 193,336,063 131,714,225 69,524,148 32,829,003
Shares (Diluted) 7-point trend, +2177.6% 747,702,265 718,541,896 619,646,180 193,336,063 131,714,225 69,524,148 32,829,003
EBITDA 5-point trend, -324.9% · $-226M $-610M $-72M $-86M $-53M ·
Balance Sheet 29
Annual Balance Sheet data for SMMT
Metric Trend 2025202420232022202120202019
Cash & Equivalents 7-point trend, +252.8% $225M $105M $71M $349M $72M $66M $64M
Short-term Investments 4-point trend, +488182000.00 $488M $307M $115M $0 · · ·
Receivables 5-point trend, -100.0% · · $0 $349.0K $1M $331.0K $541.0K
Prepaid Expense 7-point trend, -25.4% $7M $11M $3M $2M $7M $10M $9M
Other Current Assets 5-point trend, -87.1% · · $181.0K $486.0K $1M $2M $1M
Current Assets 7-point trend, +804.6% $720M $424M $190M $657M $97M $88M $80M
PP&E (Net) 7-point trend, +104.4% $1M $254.0K $204.0K $906.0K $694.0K $725.0K $518.0K
PP&E (Gross) 6-point trend, -11.0% · $1M $1M $2M $2M $2M $2M
Accum. Depreciation 6-point trend, +9.2% · $1M $1M $1M $1M $1M $1M
Goodwill 7-point trend, +2.0% $2M $2M $2M $2M $2M $2M $2M
Intangibles 6-point trend, -100.0% · $0 $0 $0 $10M $12M $13M
Other Non-current Assets 6-point trend, +7205000.00 $7M $3M $4M $577.0K $170.0K $0 ·
Total Assets 7-point trend, +680.5% $751M $436M $203M $664M $113M $102M $96M
Accounts Payable 7-point trend, +353.9% $20M $5M $3M $355.0K $4M $6M $4M
Accrued Liabilities 7-point trend, +459.3% $32M $20M $9M $11M $7M $3M $6M
Short-term Debt 2-point trend, -100.0% · · $0 $20M · · ·
Current Liabilities 7-point trend, +430.2% $73M $42M $20M $39M $26M $20M $14M
Capital Leases 7-point trend, +4047.4% $18M $3M $3M $3M $2M $75.0K $422.0K
Deferred Tax · · · · · · $2M
Other Non-current Liabilities 7-point trend, -32.2% $2M $2M $2M $1M $3M $3M $3M
Total Liabilities 7-point trend, +431.0% $92M $47M $125M $538M $30M $23M $17M
Total Debt · · $0 · · · ·
Common Stock 7-point trend, +1053.9% $8M $7M $7M $2M $980.0K $826.0K $672.0K
Paid-in Capital 7-point trend, +1122.1% $2.95B $1.60B $1.07B $505M $384M $293M $241M
Retained Earnings 7-point trend, -1349.7% $-2.29B $-1.21B $-993M $-378M $-300M $-211M $-158M
AOCI 7-point trend, +46.7% $-3M $-2M $-2M $-2M $-2M $-4M $-5M
Stockholders' Equity 7-point trend, +735.4% $659M $389M $78M $127M $83M $79M $79M
Liabilities + Equity 7-point trend, +680.5% $751M $436M $203M $664M $113M $102M $96M
Shares Outstanding 7-point trend, +1054.2% 775,371,200 737,626,004 701,660,053 211,091,425 98,039,540 82,575,064 67,178,054
Cash Flow 14
Annual Cash Flow data for SMMT
Metric Trend 2025202420232022202120202019
Stock-based Comp 7-point trend, +86576.9% $732M $51M $14M $12M $13M $2M $845.0K
Deferred Tax Flat — no change across 3 periods · · · · $0 $0 $0
Amort. of Intangibles 6-point trend, -100.0% · $0 $0 $914.0K $1M $1M $970.0K
Operating Cash Flow 7-point trend, -1455.8% $-323M $-142M $-77M $-42M $-73M $-48M $-21M
CapEx 7-point trend, +220.5% $657.0K $139.0K $128.0K $624.0K $306.0K $421.0K $205.0K
Investing Cash Flow 7-point trend, -51017.3% $-174M $-205M $-588M $-624.0K $-306.0K $-421.0K $-341.0K
Stock Issued 5-point trend, +107.6% · · $105M $100M $75M $50M $50M
Net Stock Activity 4-point trend, +109.4% · · $105M $100M $75M $50M ·
Dividends Paid Flat — no change across 2 periods · · · · · $0 $0
Financing Cash Flow 7-point trend, +1147.4% $618M $381M $87M $620M $78M $51M $50M
Net Change in Cash 7-point trend, +321.0% $120M $34M $-577M $577M $5M $3M $29M
Taxes Paid 7-point trend, -100.0% $0 $0 $52.0K $0 $7.0K $-70.0K $63.0K
Free Cash Flow 6-point trend, -566.7% $-324M $-142M $-77M $-42M $-73M $-49M ·
Levered FCF 2-point trend, -50.0% · · · · $-73M $-49M ·
Profitability 7
Annual Profitability data for SMMT
Metric Trend 2025202420232022202120202019
Operating Margin 3-point trend, -65.3% · · · -10225.4% -4764.3% -6185.2% ·
Net Margin 3-point trend, -82.4% · · · -11174.8% -4897.8% -6127.6% ·
Pretax Margin 3-point trend, -81.6% · · · -11174.8% -4897.8% -6152.3% ·
EBITDA Margin 3-point trend, -65.3% · · · -10225.4% -4764.3% -6185.2% ·
ROA 6-point trend, -243.1% -181.9% -69.3% -141.8% -20.3% -82.1% -53.0% ·
ROE 6-point trend, -163.2% -235.1% -53.5% -694.6% -60.6% -95.5% -89.3% ·
ROIC 2-point trend, -55.2% · · · · -103.5% -66.7% ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for SMMT
Metric Trend 2025202420232022202120202019
Current Ratio 6-point trend, +123.9% 9.9 10.2 9.3 16.9 3.8 4.4 ·
Quick Ratio 6-point trend, +191.3% 9.8 9.9 9.1 9.0 2.9 3.4 ·
Debt / Equity · · 0.0 · · · ·
Interest Coverage 3-point trend, +92.1% · · · -16.4 -306.7 -208.6 ·
Efficiency 2
Annual Efficiency data for SMMT
Metric Trend 2025202420232022202120202019
Asset Turnover 5-point trend, -100.0% · 0.0 0.0 0.0 0.0 0.0 ·
Receivables Turnover 4-point trend, -100.0% · · 0.0 0.8 2.0 2.0 ·
Per Share 5
Annual Per Share data for SMMT
Metric Trend 2025202420232022202120202019
Book Value / Share 6-point trend, -11.7% $0.85 $0.53 $0.11 $0.60 $0.85 $0.96 ·
Revenue / Share 5-point trend, -100.0% · $0.00 $0.00 $0.00 $0.02 $0.01 ·
Cash Flow / Share 6-point trend, +37.6% $-0.43 $-0.20 $-0.12 $-0.22 $-0.79 $-0.69 ·
Cash / Share 6-point trend, -63.9% $0.29 $0.14 $0.10 $1.65 $0.73 $0.80 ·
EPS (TTM) 6-point trend, -89.5% $-1.44 $-0.31 $-0.99 $-0.41 $-0.67 $-0.76 ·
Growth Rates 1
Annual Growth Rates data for SMMT
Metric Trend 2025202420232022202120202019
Revenue YoY 2-point trend, -155.3% · · · -61.0% 110.3% · ·
Valuation (TTM) 16
Annual Valuation (TTM) data for SMMT
Metric Trend 2025202420232022202120202019
Revenue TTM 5-point trend, -100.0% · $0 $0 $705.0K $2M $860.0K ·
Net Income TTM 6-point trend, -1948.7% $-1.08B $-221M $-615M $-79M $-89M $-53M ·
Market Cap 6-point trend, +3394.2% $13.56B $13.16B $1.83B $897M $264M $388M ·
Enterprise Value · · $1.65B · · · ·
P/E 6-point trend, -96.4% -12.1 -57.6 -2.6 -10.4 -4.0 -6.2 ·
P/S 3-point trend, +182.0% · · · 1272.5 145.8 451.3 ·
P/B 6-point trend, +321.4% 20.6 33.9 23.6 7.1 3.2 4.9 ·
P / Tangible Book 6-point trend, +250.6% 20.6 34.0 24.2 7.2 3.7 5.9 ·
P / Cash Flow 6-point trend, -420.6% -42.0 -92.6 -23.9 -21.6 -3.6 -8.1 ·
P / FCF 6-point trend, -424.1% -41.9 -92.5 -23.8 -21.3 -3.6 -8.0 ·
EV / EBITDA · · -2.7 · · · ·
EV / FCF · · -21.4 · · · ·
Dividend Yield · · · · · 0.00% ·
Earnings Yield 6-point trend, +49.1% -8.2% -1.7% -37.9% -9.7% -24.9% -16.2% ·
Payout Ratio · · · · · 0.00% ·
Annual Payout · · · · · $0 ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $0$0$705.0K$2M
Operating Margin % -10225.4%-4764.3%
Net Income $-1.08B$-221M$-615M$-79M$-89M
Diluted EPS $-1.44$-0.31$-0.99$-0.41$-0.67
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.0
Current Ratio 9.910.29.316.93.8
Quick Ratio 9.89.99.19.02.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-324M$-142M$-77M$-42M$-73M

Latest News Recent headlines mentioning this company

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Institutional owners (13F) 283 filers · $1.7B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
71 (+13 vs prior Q) 33 (-2 vs prior Q) 93 (+13 vs prior Q) 59 (+7 vs prior Q) +36.9M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BAKER BROS. ADVISORS LP $477,697,090 32,786,348 28.68% Shares
STATE STREET CORP $138,951,118 9,536,796 8.34% Shares
FMR LLC $94,914,750 6,514,396 5.70% Shares
VANGUARD CAPITAL MANAGEMENT LLC $83,551,432 5,734,484 5.02% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $73,464,708 5,042,190 4.41% Shares
GOLDMAN SACHS GROUP INC $61,480,859 4,219,688 3.69% Shares
Point72 Asset Management, L.P. $53,876,990 3,697,803 3.23% Shares
GEODE CAPITAL MANAGEMENT, LLC $44,229,190 3,034,612 2.66% Shares
MILLENNIUM MANAGEMENT LLC $34,226,110 2,349,081 2.05% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $28,988,341 1,989,591 1.74% Shares
Balyasny Asset Management L.P. $27,744,981 1,904,254 1.67% Shares
CITADEL ADVISORS LLC $25,143,682 1,725,716 1.51% Shares
Aberdeen Group plc $24,676,131 1,693,626 1.48% Shares
Squarepoint Ops LLC $23,177,024 1,590,736 1.39% Shares
NORGES BANK $20,143,302 1,382,519 1.21% Shares
Logos Global Management LP $19,669,500 1,350,000 1.18% Shares
Octagon Capital Advisors LP $18,212,500 1,250,000 1.09% Shares
Kynam Capital Management, LP $17,484,000 1,200,000 1.05% Shares
D. E. Shaw & Co., Inc. $17,311,826 1,188,183 1.04% Shares
Pictet Asset Management Holding SA $16,434,565 1,134,299 0.99% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $16,161,044 1,109,200 0.97% Put option
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $14,232,719 976,851 0.85% Shares
VANGUARD FIDUCIARY TRUST CO $14,083,143 966,585 0.85% Shares
APEIRON CAPITAL Ltd $14,014,388 961,866 0.84% Shares
DIADEMA PARTNERS LP $12,533,114 860,200 0.75% Call option
SCHRODER INVESTMENT MANAGEMENT GROUP $11,970,990 835,963 0.72% Shares
LMR Partners LLP $11,953,228 820,400 0.72% Put option
SUSQUEHANNA INTERNATIONAL GROUP, LLP $11,226,185 770,500 0.67% Call option
Rock Springs Capital Management LP $10,417,550 715,000 0.63% Shares
TWO SIGMA INVESTMENTS, LP $10,151,123 696,714 0.61% Shares
BANK OF AMERICA CORP /DE/ $9,459,748 649,262 0.57% Shares
CITADEL ADVISORS LLC $9,352,483 641,900 0.56% Call option
Candriam S.C.A. $7,750,071 532,432 0.47% Shares
Cutter Capital Management, LP $7,716,000 400,000 0.46% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $7,595,909 521,339 0.46% Shares
CITADEL ADVISORS LLC $7,394,275 507,500 0.44% Put option
Elmind Capital, LP $7,194,957 493,820 0.43% Shares
WORLDQUANT MILLENNIUM ADVISORS LLC $6,280,078 431,028 0.38% Shares
TD Asset Management Inc $6,208,044 426,084 0.37% Shares
BlackRock, Inc. $5,282,368 362,551 0.32% Shares
QVT Financial LP $5,252,835 360,524 0.32% Shares
CITIGROUP INC $5,111,127 350,798 0.31% Shares
Ghisallo Capital Management LLC $5,099,500 350,000 0.31% Shares
HOHIMER WEALTH MANAGEMENT, LLC $4,940,687 339,100 0.30% Shares
JANE STREET GROUP, LLC $4,841,611 332,300 0.29% Put option
Caption Management, LLC $4,758,562 326,600 0.29% Call option
JANE STREET GROUP, LLC $4,391,398 301,400 0.26% Call option
MANUFACTURERS LIFE INSURANCE COMPANY, THE $4,341,860 298,000 0.26% Shares
BNP PARIBAS FINANCIAL MARKETS $4,005,206 274,894 0.24% Shares
DARK FOREST CAPITAL MANAGEMENT LP $3,549,354 243,607 0.21% Shares
Squarepoint Ops LLC $3,509,913 240,900 0.21% Call option
WELLINGTON MANAGEMENT GROUP LLP $3,498,971 240,149 0.21% Shares
Polymer Capital Management (HK) LTD $3,276,108 224,853 0.20% Shares
SECTORAL ASSET MANAGEMENT INC $3,208,023 220,180 0.19% Shares
Woodline Partners LP $3,125,367 214,507 0.19% Shares
BARCLAYS PLC $3,041,415 208,745 0.18% Shares
Rafferty Asset Management, LLC $3,010,526 206,625 0.18% Shares
DIADEMA PARTNERS LP $2,914,000 200,000 0.17% Put option
GRIFFIN ASSET MANAGEMENT, INC. $2,820,490 193,582 0.17% Shares
ADAR1 Capital Management, LLC $2,795,531 191,869 0.17% Shares
WOLVERINE TRADING, LLC $2,757,148 130,300 0.17% Call option
Trexquant Investment LP $2,681,069 184,013 0.16% Shares
Focus Partners Wealth $2,481,826 170,338 0.15% Shares
Springhill Fund Asset Management (HK) Co Ltd $2,397,882 124,307 0.14% Shares
China Universal Asset Management Co., Ltd. $1,945,488 133,527 0.12% Shares
RHUMBLINE ADVISERS $1,848,821 126,895 0.11% Shares
Beacon Pointe Advisors, LLC $1,789,711 94,394 0.11% Shares
HSBC HOLDINGS PLC $1,783,685 120,560 0.11% Shares
TEMA ETFS LLC $1,675,227 95,782 0.10% Shares
Quantinno Capital Management LP $1,652,996 113,452 0.10% Shares
Cerity Partners LLC $1,645,389 112,930 0.10% Shares
WOLVERINE TRADING, LLC $1,574,304 74,400 0.09% Put option
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $1,511,036 79,696 0.09% Shares
BANK OF MONTREAL /CAN/ $1,490,074 102,270 0.09% Shares
Caption Management, LLC $1,487,597 102,100 0.09% Put option
PROFUND ADVISORS LLC $1,464,999 100,549 0.09% Shares
LMR Partners LLP $1,458,457 100,100 0.09% Call option
Affinity Asset Advisors, LLC $1,457,000 100,000 0.09% Call option
Caption Management, LLC $1,457,000 100,000 0.09% Shares
NOMURA HOLDINGS INC $1,440,973 98,900 0.09% Call option
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $1,372,917 94,229 0.08% Shares
AXQ CAPITAL, LP $1,364,102 93,624 0.08% Shares
Schonfeld Strategic Advisors LLC $1,333,983 91,557 0.08% Shares
Wealth Management Partners, LLC $1,300,722 89,274 0.08% Shares
XTX Topco Ltd $1,186,027 81,402 0.07% Shares
DIMENSIONAL FUND ADVISORS LP $1,166,736 80,078 0.07% Shares
Seven Fleet Capital Management LP $1,090,930 73,300 0.07% Shares
UBS Group AG $1,076,432 73,880 0.06% Shares
NICOLET BANKSHARES INC $1,057,680 72,593 0.06% Shares
UBS Group AG $1,054,868 72,400 0.06% Call option
VANGUARD GROUP INC $1,019,247 58,276 0.06% Shares
Engineers Gate Manager LP $988,880 67,871 0.06% Shares
VARCOV Co. $931,853 63,957 0.06% Shares
Illinois Municipal Retirement Fund $914,034 62,734 0.05% Shares
Bridgefront Capital, LLC $880,261 60,416 0.05% Shares
Police & Firemen's Retirement System of New Jersey $879,110 60,337 0.05% Shares
DIADEMA PARTNERS LP $874,200 60,000 0.05% Shares
Assenagon Asset Management S.A. $868,678 59,621 0.05% Shares
Vanguard Global Advisers, LLC $861,160 59,105 0.05% Shares
Entropy Technologies, LP $830,738 57,017 0.05% Shares

Company insiders 11 insiders · 6 officers · 7 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Mahkam Zanganeh Co-Chief Executive Officer June 12, 2026 P 573,883,879 2 0 $51,447,200
Robert W. Duggan Co-Chief Executive Officer June 12, 2026 P 573,883,879 3 0 $51,947,183
Manmeet Singh Soni COO and CFO June 4, 2026 P 3,123,603 1 0 $361,500
Donaldson Michael Paul Chief Financial Officer Feb. 19, 2021 D 0 0 $0
David Jonathan Powell Chief Scientific Officer Nov. 30, 2020 X 0 0 0 $0
Camilla Graham Chief Clinical Affairs Officer Oct. 4, 2020 A 0 0 $0
Urte Gayko Director Nov. 3, 2021 A 0 0 $0
Kenneth A Clark Director Oct. 7, 2021 A 0 0 $0
Ujwala Mahatme Director Feb. 19, 2021 A 0 0 $0
Rainer M Erdtmann Director Feb. 19, 2021 A 0 0 $0
Luhua Wang Feb. 28, 2021 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 3 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
ROBERT W. DUGGAN ×14 filings Sept. 13, 2024 Initial filing SEC
MAHKAM ZANGANEH, MAHKAM ZANGANEH REVOCABLE TRUST, SHAUN ZANGANEH IRREVOCABLE TRUST ×5 filings March 13, 2023 Initial filing SEC
Lansdowne Partners (UK) LLP, Lansdowne Developed Markets Master Fund Limited ×8 filings June 17, 2020 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 51 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
CANC · Tema ETF Trust 1.21% 121,097 NS May 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 1.15% 278,847 NS April 30, 2026 N-PORT
BBC · ETFis Series Trust I 0.90% 15,708 NS April 30, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.74% 42,238 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.68% 28,664 NS May 31, 2026 N-PORT
QQQJ · Invesco Exchange-Traded Fund Trust … 0.27% 230,485 SH Aug. 8, 2026 Daily
GSEW · Goldman Sachs ETF Trust 0.19% 196,432 NS May 31, 2026 N-PORT
IQSM · New York Life Investments ETF Trust 0.14% 20,619 NS April 30, 2026 N-PORT
IBB · iShares Trust 0.14% 987,912 SH Aug. 8, 2026 Daily
EQAL · Invesco Exchange-Traded Fund Trust … 0.09% 52,876 SH Aug. 8, 2026 Daily
BKMC · BNY Mellon ETF Trust 0.08% 23,464 NS April 30, 2026 N-PORT
IWP · iShares Trust 0.05% 788,572 SH Aug. 8, 2026 Daily
SCHM · SCHWAB STRATEGIC TRUST 0.05% 416,668 NS May 31, 2026 N-PORT
BBMC · J.P. Morgan Exchange-Traded Fund Tr… 0.05% 45,768 NS April 30, 2026 N-PORT
VBR · VANGUARD INDEX FUNDS 0.04% 1,691,686 SH Aug. 8, 2026 Daily
ONEQ · Fidelity Commonwealth Trust 0.03% 191,092 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.03% 1,777,877 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.03% 397,116 SH Aug. 8, 2026 Daily
IYH · iShares Trust 0.03% 80,776 SH Aug. 8, 2026 Daily
SMMD · iShares Trust 0.02% 67,355 SH Aug. 8, 2026 Daily
IMCG · iShares Trust 0.02% 71,102 SH Aug. 8, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.02% 2,673,084 SH Aug. 8, 2026 Daily
IWR · iShares Trust 0.01% 546,092 SH Aug. 8, 2026 Daily
IMCB · iShares Trust 0.01% 15,238 SH Aug. 8, 2026 Daily
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 4,699 NS May 31, 2026 N-PORT
VONG · VANGUARD SCOTTSDALE FUNDS 0.01% 215,152 SH Aug. 8, 2026 Daily
SCHV · SCHWAB STRATEGIC TRUST 0.01% 79,133 NS May 31, 2026 N-PORT
GGUS · Goldman Sachs ETF Trust 0.01% 2,012 NS May 31, 2026 N-PORT
ILCG · iShares Trust 0.01% 13,322 SH Aug. 8, 2026 Daily
IWF · iShares Trust 0.01% 509,396 SH Aug. 8, 2026 Daily
TILT · FlexShares Trust 0.01% 5,027 NS April 30, 2026 N-PORT
SCHX · SCHWAB STRATEGIC TRUST 0.00% 175,386 NS May 31, 2026 N-PORT
SCHK · SCHWAB STRATEGIC TRUST 0.00% 13,098 NS May 31, 2026 N-PORT
RECS · Columbia ETF Trust I 0.00% 9,805 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 93,014 NS May 31, 2026 N-PORT
GUSA · Goldman Sachs ETF Trust II 0.00% 4,934 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 217,671 SH Aug. 8, 2026 Daily
IYY · iShares Trust 0.00% 6,342 SH Aug. 8, 2026 Daily
ILCB · iShares Trust 0.00% 2,192 SH Aug. 8, 2026 Daily
IWB · iShares Trust 0.00% 81,245 SH Aug. 8, 2026 Daily
IWV · iShares Trust 0.00% 31,692 SH Aug. 8, 2026 Daily
MSLC · MORGAN STANLEY PATHWAY FUNDS 0.00% 4,355 NS May 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.00% 816 NS April 30, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 785 NS April 30, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 2,425 NS April 30, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 180 NS April 30, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 3,708,976 SH Aug. 8, 2026 Daily
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.00% 110,173 SH Aug. 8, 2026 Daily
VONE · VANGUARD SCOTTSDALE FUNDS 0.00% 23,019 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 11,466 SH Aug. 8, 2026 Daily