SOPH SOPHiA GENETICS SA - Ordinary Shares
NASDAQ · Health Care · View on SEC EDGAR ↗ 10-K/10-Q Mar 3, 2026
$7.35
· of 52w range
· above low
· to high
$3.8352w low
$8.9852w high
P/E
-4.0
EPS
$-1.17
your badges
52W Range
$4–$9
Analyst Rating
BUY
Price Target
$10
P/E
-4.0
ROE
-110.0%
Net Profit Margin
·
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SOPH Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$7.35
P/E
-4.0
EPS
$-1.17
ROE
-110.0%
52W Range
$4–$9
SOPH Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
EPS$-1.172020-12-31 → 2025-12-31
Free Cash Flow$-36M2021-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | SOPH | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -4.05Y avg ≈-4.6 | ≈-4.6 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | SOPH | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -49.6%5Y avg ≈-36.6% | ≈-36.6% | · | · | |
| ROE | -110.0%5Y avg ≈-56.3% | ≈-56.3% | · | · | |
| ROIC | -153.3%5Y avg ≈-79.3% | ≈-79.3% | · | · |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | SOPH | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio | 2.05Y avg ≈5.4 | ≈5.4 | · | · | |
| Quick Ratio | 1.05Y avg ≈1.1 | ≈1.1 | · | · | |
| Interest Coverage | -15.65Y avg ≈-78.8 | ≈-78.8 | · | · |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
| Metric | 5Y trend | SOPH | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Inventory Turnover | 4.15Y avg ≈3.4 | ≈3.4 | · | · |
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-17.4%
Next Report
Nov 10, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 11, 2026 | $-0.28 | $-0.21 | -30.7% |
| March 31, 2026 | May 12, 2026 | $-0.27 | $-0.24 | -13.8% |
| Dec. 31, 2025 | $-0.25 | $-0.24 | -3.2% | |
| Sept. 30, 2025 | $-0.28 | $-0.25 | -13.2% | |
| June 30, 2025 | $-0.33 | $-0.23 | -40.7% | |
| March 31, 2025 | $-0.26 | $-0.25 | -3.0% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cost of Revenue | $25M | $21M | $19M | $16M | $15M | $11M | |
| Gross Profit | $52M | $44M | $43M | $31M | $25M | $18M | |
| R&D Expense | $34M | $34M | $37M | $35M | $27M | $19M | |
| SG&A Expense | $53M | $47M | $53M | $56M | $42M | $19M | |
| Operating Income | $-71M | $-67M | $-75M | $-88M | $-71M | $-37M | |
| Interest Expense | $5M | $2M | $588.0K | $639.0K | $658.0K | $840.0K | |
| Interest Income | $2M | $3M | $5M | $1M | $20.0K | $96.0K | |
| Pretax Income | $-77M | $-61M | $-78M | $-88M | $-74M | $-41M | |
| Income Tax | $2M | $1M | $486.0K | $-136.0K | $168.0K | $-2M | |
| Net Income | $-79M | $-62M | $-79M | $-87M | $-74M | $-39M | |
| EPS (Basic) | $-1.17 | $-0.95 | $-1.22 | $-1.36 | $-1.33 | $-0.93 | |
| EPS (Diluted) | $-1.17 | $-0.95 | $-1.22 | $-1.36 | $-1.33 | $-0.93 | |
| Shares (Basic) | 67,539,835 | 66,062,205 | 64,750,886 | 64,099,213 | 55,299,863 | 42,350,757 | |
| Shares (Diluted) | 67,539,835 | 66,062,205 | 64,750,886 | 64,099,213 | 55,299,863 | 42,350,757 | |
| EBITDA | $-71M | $-67M | $-75M | $-88M | · | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $37M | $14M | $16M | $26M | $40M | $43M | |
| Receivables | $15M | $7M | $14M | $7M | $6M | $6M | |
| Inventory | $6M | $6M | $6M | $5M | $6M | $3M | |
| Current Assets | $99M | $99M | $148M | $196M | $283M | $110M | |
| PP&E (Net) | $6M | $5M | $7M | $7M | $5M | $2M | |
| Intangibles | $36M | $29M | $27M | $20M | $16M | $13M | |
| Total Assets | $163M | $155M | $206M | $244M | $320M | $132M | |
| Current Liabilities | $51M | $27M | $36M | $27M | $29M | $22M | |
| Total Liabilities | $116M | $59M | $55M | $44M | $45M | $32M | |
| Retained Earnings | $-519M | $-440M | $-378M | $-299M | $-211M | $-138M | |
| Stockholders' Equity | $47M | $96M | $151M | $200M | $275M | $101M |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Operating Cash Flow | $-36M | $-45M | $-53M | $-70M | $-58M | $-32M | |
| CapEx | $574.0K | $244.0K | $1M | $4M | $3M | $450.0K | |
| Investing Cash Flow | $-9M | $-5M | $13M | $42M | $-57M | $-24M | |
| Financing Cash Flow | $30M | $10M | $-3M | $-2M | $238M | $107M | |
| Free Cash Flow | $-36M | $-43M | $-50M | $-74M | $-61M | · | |
| Levered FCF | $-41M | $-45M | $-51M | $-75M | $-61M | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -49.6% | -34.6% | -35.1% | -31.0% | -32.6% | · | |
| ROE | -110.0% | -50.4% | -44.9% | -36.8% | -39.2% | · | |
| ROIC | -153.3% | -70.4% | -49.7% | -43.8% | · | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 2.0 | 3.7 | 4.2 | 7.3 | 9.9 | · | |
| Quick Ratio | 1.0 | 0.8 | 0.8 | 1.2 | 1.6 | · | |
| Interest Coverage | -15.6 | -34.8 | -127.3 | -137.4 | · | · |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Inventory Turnover | 4.1 | 3.4 | 3.3 | 3.0 | 3.3 | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash Flow / Share | $-0.53 | $-0.65 | $-0.75 | $-1.09 | · | · | |
| EPS (TTM) | $-1.17 | $-0.95 | $-1.22 | $-1.36 | $-1.33 | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-79M | $-62M | $-79M | $-87M | $-74M | · | |
| P/E | -4.0 | -3.2 | -3.9 | -1.5 | -10.6 | · | |
| Earnings Yield | -25.1% | -30.9% | -25.9% | -66.0% | -9.4% | · |
Per Share
| Metric | Trend | Q4 2024 |
|---|---|---|
| EPS (TTM) | $-0.95 |
Valuation (TTM)
| Metric | Trend | Q4 2024 |
|---|---|---|
| Net Income TTM | $-62M | |
| P/E | -3.2 | |
| Earnings Yield | -30.9% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Net Income | $-79M | $-62M | $-79M | $-87M | $-74M |
| Diluted EPS | $-1.17 | $-0.95 | $-1.22 | $-1.36 | $-1.33 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 2.0 | 3.7 | 4.2 | 7.3 | 9.9 |
| Quick Ratio | 1.0 | 0.8 | 0.8 | 1.2 | 1.6 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | $-36M | $-43M | $-50M | $-74M | $-61M |
Institutional owners (13F) 73 filers · $225.3M total · As of Sept. 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
73
Value held
$225.3M
New positions
27
Exited positions
3
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 27 (+10 vs prior Q) | 3 (-7 vs prior Q) | 16 (+5 vs prior Q) | 16 (+8 vs prior Q) | +13.0M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| GENERATION INVESTMENT MANAGEMENT LLP | $39,175,761 | 6,789,560 | 17.39% | Shares |
| AIGH Capital Management LLC | $22,815,699 | 3,954,194 | 10.13% | Shares |
| AKRE CAPITAL MANAGEMENT LLC | $21,459,438 | 3,719,140 | 9.52% | Shares |
| ROYCE & ASSOCIATES LP | $19,512,617 | 3,381,736 | 8.66% | Shares |
| BANQUE PICTET & CIE SA | $18,505,386 | 2,208,280 | 8.21% | Shares |
| PRINCIPAL FINANCIAL GROUP INC | $13,641,756 | 2,364,256 | 6.05% | Shares |
| AMERIPRISE FINANCIAL INC | $12,790,670 | 2,216,752 | 5.68% | Shares |
| AWM Investment Company, Inc. | $9,809,000 | 1,700,000 | 4.35% | Shares |
| Soleus Capital Management, L.P. | $9,030,050 | 1,565,000 | 4.01% | Shares |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $8,242,272 | 1,428,470 | 3.66% | Shares |
| Alta Wealth Advisors LLC | $8,130,853 | 1,409,160 | 3.61% | Shares |
| ESSEX INVESTMENT MANAGEMENT CO LLC | $5,389,421 | 643,129 | 2.39% | Shares |
| KENNEDY CAPITAL MANAGEMENT LLC | $5,296,727 | 917,977 | 2.35% | Shares |
| Archon Capital Management LLC | $3,989,453 | 691,413 | 1.77% | Shares |
| Sowell Financial Services LLC | $2,865,030 | 341,889 | 1.27% | Shares |
| Ensign Peak Advisors, Inc | $2,565,654 | 444,654 | 1.14% | Shares |
| Hodges Capital Management Inc. | $2,360,351 | 409,073 | 1.05% | Shares |
| Bank Pictet & Cie (Europe) AG | $2,138,576 | 255,200 | 0.95% | Shares |
| JANE STREET GROUP, LLC | $1,749,464 | 303,200 | 0.78% | Call option |
| 1492 Capital Management LLC | $1,282,059 | 222,194 | 0.57% | Shares |
| EDMOND DE ROTHSCHILD HOLDING S.A. | $1,154,023 | 200,004 | 0.51% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $993,594 | 172,200 | 0.44% | Call option |
| SEI INVESTMENTS CO | $952,303 | 165,045 | 0.42% | Shares |
| Maven Securities LTD | $865,500 | 150,000 | 0.38% | Shares |
| CITADEL ADVISORS LLC | $857,999 | 148,700 | 0.38% | Call option |
| FEDERATED HERMES, INC. | $819,294 | 141,992 | 0.36% | Shares |
| MILLENNIUM MANAGEMENT LLC | $798,620 | 138,409 | 0.35% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $653,741 | 113,300 | 0.29% | Shares |
| Silverberg Bernstein Capital Management LLC | $653,548 | 77,989 | 0.29% | Shares |
| Rathbones Group PLC | $647,007 | 112,133 | 0.29% | Shares |
| JANE STREET GROUP, LLC | $623,518 | 108,062 | 0.28% | Shares |
| Quadrature Capital Ltd | $597,316 | 103,521 | 0.27% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $571,945 | 99,124 | 0.25% | Shares |
| UBS Group AG | $469,932 | 81,444 | 0.21% | Shares |
| Green Alpha Advisors, LLC | $361,203 | 43,103 | 0.16% | Shares |
| TWO SIGMA INVESTMENTS, LP | $336,581 | 58,333 | 0.15% | Shares |
| XTX Topco Ltd | $329,698 | 57,140 | 0.15% | Shares |
| Longaeva Partners L.P. | $288,500 | 50,000 | 0.13% | Shares |
| StoneX Group Inc. | $229,892 | 45,523 | 0.10% | Shares |
| CITADEL ADVISORS LLC | $222,128 | 38,497 | 0.10% | Shares |
| MORGAN STANLEY | $216,359 | 37,497 | 0.10% | Shares |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $189,873 | 32,907 | 0.08% | Shares |
| Pathstone Holdings, LLC | $184,845 | 32,203 | 0.08% | Shares |
| GOLDMAN SACHS GROUP INC | $170,780 | 29,598 | 0.08% | Shares |
| FRANKLIN RESOURCES INC | $129,277 | 22,405 | 0.06% | Shares |
| BANK OF AMERICA CORP /DE/ | $128,671 | 22,300 | 0.06% | Shares |
| AXQ CAPITAL, LP | $118,816 | 20,592 | 0.05% | Shares |
| HEIGHTS CAPITAL MANAGEMENT, INC | $115,400 | 20,000 | 0.05% | Shares |
| Centiva Capital, LP | $108,874 | 18,869 | 0.05% | Shares |
| Persistent Asset Partners Ltd | $108,516 | 18,807 | 0.05% | Shares |
Activists & 5%+ owners 1 position
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| aMoon Growth Fund Limited Partnership, aMoon Growth Fund G.P. Limited Partnership, aMoon General Partner Ltd., aMoon Edge Limited Partnership, aMoon Edge GP Ltd., Hilliyon Holdings Ltd., Berko Capital Ltd., Dr. Yair C. Schindel, Dr. Tomer Berkovitz ×2 filings | May 18, 2023 | · | Initial filing | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 14 insiders · 9 officers · 7 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Ross Muken | Chief Executive Officer | Oct. 5, 2026 S | 660,391 | 0 | 14 | $-249,708 |
| George Cardoza | Chief Financial Officer | Oct. 5, 2026 S | 306,726 | 1 | 8 | $32,563 |
| Zhenyu Xu | Chief Scientific Officer | Oct. 13, 2026 S | 541,493 | 0 | 27 | $-813,987 |
| Philippe Menu | Chief Medical Officer | Oct. 12, 2026 S | 195,993 | 0 | 24 | $-538,889 |
| Jurgi Camblong | Executive Chairman | Oct. 12, 2026 S | 3,387,150 | 0 | 34 | $-2,731,980 |
| Kevin Puylaert | Chief Sales Officer | Oct. 5, 2026 S | 147,732 | 0 | 12 | $-6,346 |
| Abhimanyu Verma | Chief Technology Officer | Oct. 5, 2026 S | 166,887 | 0 | 9 | $-283,129 |
| Manuela Valente | Chief People Officer | Oct. 5, 2026 S | 206,210 | 0 | 9 | $-183,544 |
| Daan Van Well | Chief Legal Officer | Oct. 5, 2026 S | 332,716 | 0 | 10 | $-166,466 |
| Kathy L Hibbs | Director | Sept. 8, 2026 S | 96,992 | 0 | 3 | $-140,124 |
| Jean-Michel Cossery | Director | June 18, 2026 A | 206,212 | 0 | 0 | $0 |
| Vincent Ossipow | Director | June 18, 2026 A | 522,860 | 0 | 0 | $0 |
| Troy Cox | Director | June 18, 2026 A | 328,743 | 0 | 0 | $0 |
| Didier Hirsch | Director | June 18, 2026 A | 240,220 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
SOPH Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 11 analysts
BUY
Median target
$9.00
+22.4%
4 36.4%
Strong Buy
6 54.5%
Buy
1 9.1%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
4 analysts · 2026-10-22Mean target $9.75 +32.7%
Now
Current price $7.35
Low$7.00
Mean$9.75
High$14.00
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Source: SEC 20-F filed Mar 3, 2026