ALPS Medical Breakthroughs ETF (SBIO)
$56.15
▼ -0.49 (-0.87%)
1-day change
$55.93 – $70.85
52-week range
Holdings data is not available for this fund yet.
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Performance as of Oct. 2, 2026
| Period | Price return | Total return |
|---|---|---|
| 1M | ▼ -17.29% | ▼ -17.29% |
| 3M | · | · |
| 6M | · | · |
| YTD | · | · |
| 1Y | · | · |
| 3Y | · | · |
| 5Y | · | · |
| Max | ▼ -18.73% | ▼ -18.73% |
Volatility 1Y·
Volatility 3Y·
Max drawdown 3Y
·
Beta 3Y·
Sharpe 1Y*·
Total return assumes dividends are reinvested. Returns are not benchmarked against an index. * Sharpe ratio is computed with a 0% risk-free rate.
Fund flows (SEC-reported)
Last month (May 2026)
+$4.1M
Quarter ending May 2026
+$17.5M
Trailing 12 months
+$23.5M
Based on the fund's own SEC Form N-PORT monthly flow disclosures (Item C.9 "Flow Information") — sales minus redemptions, reinvested distributions excluded. This is a different, independent metric from the "Net flows" estimate above (which is derived from daily shares-outstanding changes). SEC N-PORT filing lag is up to ~60 days; the most recent month/quarter may not yet be fully reflected.
Full composition 89 holdings
| Name | CUSIP | Value | % | Balance | Category | Country |
|---|---|---|---|---|---|---|
| Alkermes Plc | G01767105 | $7.2M | 4.48 | 171,723 | EC | IE |
| Kymera Therapeutics Inc | 501575104 | $6.9M | 4.23 | 84,154 | EC | US |
| Celcuity Inc | 15102K100 | $6.3M | 3.92 | 47,693 | EC | US |
| Mirum Pharmaceuticals Inc | 604749101 | $6.3M | 3.90 | 62,199 | EC | US |
| Spyre Therapeutics Inc | 00773J202 | $6.0M | 3.68 | 80,958 | EC | US |
| Cg Oncology Inc | 156944100 | $5.4M | 3.35 | 87,032 | EC | US |
| Apogee Therapeutics Inc | 03770N101 | $4.7M | 2.93 | 57,722 | EC | US |
| Xenon Pharmaceuticals Inc | 98420N105 | $4.7M | 2.90 | 85,746 | EC | CA |
| Travere Therapeutics Inc | 89422G107 | $4.5M | 2.77 | 95,051 | EC | US |
| Dianthus Therapeutics Inc | 252828108 | $4.3M | 2.64 | 45,839 | EC | US |
| Newamsterdam Pharma Co Nv | N62509109 | $4.0M | 2.47 | 118,514 | EC | NL |
| Viking Therapeutics Inc | 92686J106 | $3.9M | 2.41 | 119,108 | EC | US |
| Crinetics Pharmaceuticals Inc | 22663K107 | $3.8M | 2.37 | 107,892 | EC | US |
| Acadia Pharmaceuticals Inc | 004225108 | $3.8M | 2.35 | 175,740 | EC | US |
| Edgewise Therapeutics Inc | 28036F105 | $3.8M | 2.33 | 110,576 | EC | US |
| Denali Therapeutics Inc | 24823R105 | $3.4M | 2.13 | 163,467 | EC | US |
| Oruka Therapeutics Inc | 687604108 | $2.9M | 1.81 | 49,896 | EC | US |
| Structure Therapeutics Inc | 86366E106 | $2.9M | 1.78 | 73,020 | EC | KY |
| Disc Medicine Inc | 254604101 | $2.7M | 1.69 | 39,334 | EC | US |
| Ideaya Biosciences Inc | 45166A102 | $2.7M | 1.65 | 90,520 | EC | US |
| Vera Therapeutics Inc | 92337R101 | $2.6M | 1.61 | 73,552 | EC | US |
| Tarsus Pharmaceuticals Inc | 87650L103 | $2.6M | 1.61 | 43,870 | EC | US |
| Relay Therapeutics Inc | 75943R102 | $2.6M | 1.60 | 184,224 | EC | US |
| Mineralys Therapeutics Inc | 603170101 | $2.6M | 1.59 | 81,578 | EC | US |
| Celldex Therapeutics Inc | 15117B202 | $2.2M | 1.33 | 68,615 | EC | US |
| Zai Lab Ltd | 98887Q104 | $2.0M | 1.26 | 115,031 | EC | KY |
| Pharvaris Nv | N69605108 | $2.0M | 1.23 | 66,026 | EC | NL |
| Sionna Therapeutics Inc | 829401108 | $2.0M | 1.23 | 46,379 | EC | US |
| Rapport Therapeutics Inc | 75383L102 | $1.9M | 1.20 | 49,264 | EC | US |
| Sarepta Therapeutics Inc | 803607100 | $1.9M | 1.20 | 108,222 | EC | US |
| Lakefront Biotherapeutics Nv | 36315X101 | $1.9M | 1.19 | 67,945 | EC | BE |
| Tyra Biosciences Inc | 90240B106 | $1.9M | 1.15 | 55,509 | EC | US |
| Novavax Inc | 670002401 | $1.8M | 1.14 | 167,949 | EC | US |
| Stoke Therapeutics Inc | 86150R107 | $1.8M | 1.12 | 58,873 | EC | US |
| Agios Pharmaceuticals Inc | 00847X104 | $1.8M | 1.10 | 60,392 | EC | US |
| Vericel Corp | 92346J108 | $1.7M | 1.08 | 52,309 | EC | US |
| Nuvation Bio Inc | 67080N101 | $1.7M | 1.06 | 357,260 | EC | US |
| Palvella Therapeutics Inc | 697947109 | $1.7M | 1.03 | 14,096 | EC | US |
| Taysha Gene Therapies Inc | 877619106 | $1.7M | 1.02 | 282,348 | EC | US |
| Amylyx Pharmaceuticals Inc | 03237H101 | $1.6M | 1.01 | 113,933 | EC | US |
| Immatics Nv | N44445109 | $1.6M | 0.98 | 138,190 | EC | NL |
| Immunocore Holdings Plc | 45258D105 | $1.5M | 0.93 | 52,254 | EC | GB |
| Mbx Biosciences Inc | 55287L101 | $1.5M | 0.90 | 46,286 | EC | US |
| Bicara Therapeutics Inc | 055477103 | $1.4M | 0.88 | 65,313 | EC | US |
| Moonlake Immunotherapeutics | 61559X104 | $1.4M | 0.88 | 73,934 | EC | KY |
| Kalvista Pharmaceuticals Inc | 483497103 | $1.4M | 0.87 | 52,105 | EC | US |
| Arrivent Biopharma Inc | 04272N102 | $1.4M | 0.85 | 45,563 | EC | US |
| Oculis Holding Ag | H5870P102 | $1.4M | 0.84 | 58,929 | EC | CH |
| Maze Therapeutics Inc | 578784100 | $1.3M | 0.81 | 49,602 | EC | US |
| Mannkind Corp | 56400P706 | $1.2M | 0.74 | 317,578 | EC | US |
Dividends 5 payments
0.00%TTM yield
$0.00TTM payout / share
Annual
(est.)
| Ex-date | Amount / share |
|---|---|
| Dec. 19, 2024 | $1.1740 |
| Dec. 21, 2023 | $0.0710 |
| Dec. 19, 2019 | $0.0160 |
| Dec. 20, 2018 | $0.7840 |
| Dec. 21, 2017 | $0.5790 |
Institutional owners (13F) 69 filers
Institutions that report holding this ETF in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | % of tracked 13F | Shares | Type | As of |
|---|---|---|---|---|---|
| BANK OF AMERICA CORP /DE/ | $27,117,996 | 35.19% | 419,459 | Shares | June 30, 2026 |
| UBS Group AG | $11,559,355 | 15.00% | 178,799 | Shares | June 30, 2026 |
| WELLS FARGO & COMPANY/MN | $4,237,173 | 5.50% | 65,540 | Shares | June 30, 2026 |
| CONNORS INVESTOR SERVICES INC | $3,112,057 | 4.04% | 48,137 | Shares | June 30, 2026 |
| MORGAN STANLEY | $2,583,180 | 3.35% | 39,956 | Shares | June 30, 2026 |
| LPL Financial LLC | $2,437,279 | 3.16% | 37,700 | Shares | June 30, 2026 |
| Moran Wealth Management, LLC | $2,200,040 | 2.85% | 34,030 | Shares | June 30, 2026 |
| GRIFFIN ASSET MANAGEMENT, INC. | $1,855,390 | 2.41% | 28,699 | Shares | June 30, 2026 |
| RAYMOND JAMES FINANCIAL INC | $1,761,330 | 2.29% | 27,244 | Shares | June 30, 2026 |
| STIFEL FINANCIAL CORP | $1,658,181 | 2.15% | 25,648 | Shares | June 30, 2026 |
| Sterling Investment Advisors, Ltd. | $1,538,670 | 2.00% | 23,800 | Shares | June 30, 2026 |
| SILVER OAK SECURITIES, INCORPORATED | $1,336,962 | 1.73% | 20,680 | Shares | June 30, 2026 |
| NTV Asset Management LLC | $1,104,416 | 1.43% | 17,083 | Shares | June 30, 2026 |
| Equitable Holdings, Inc. | $990,891 | 1.29% | 15,327 | Shares | June 30, 2026 |
| COMMONWEALTH EQUITY SERVICES, LLC | $844,140 | 1.10% | 13,057 | Shares | June 30, 2026 |
| BOK Financial Private Wealth, Inc. | $840,450 | 1.09% | 13,000 | Shares | June 30, 2026 |
| ROYAL BANK OF CANADA | $748,000 | 0.97% | 11,571 | Shares | June 30, 2026 |
| ELEVATION POINT WEALTH PARTNERS, LLC | $725,696 | 0.94% | 11,225 | Shares | June 30, 2026 |
| DAVENPORT & Co LLC | $717,615 | 0.93% | 11,100 | Shares | June 30, 2026 |
| Vestmark Advisory Solutions, Inc. | $575,256 | 0.75% | 8,898 | Shares | June 30, 2026 |
| Prospera Financial Services Inc | $573,485 | 0.74% | 8,872 | Shares | June 30, 2026 |
| Phoenix Wealth Advisors | $542,414 | 0.70% | 8,390 | Shares | June 30, 2026 |
| Kestra Advisory Services, LLC | $535,414 | 0.69% | 8,282 | Shares | June 30, 2026 |
| Savant Capital, LLC | $526,759 | 0.68% | 8,035 | Shares | June 30, 2026 |
| McGuire Investment Group, LLC | $488,108 | 0.63% | 7,550 | Shares | June 30, 2026 |
| BROWN ADVISORY INC | $468,712 | 0.61% | 7,250 | Shares | June 30, 2026 |
| MSH Capital Advisors LLC | $461,601 | 0.60% | 7,140 | Shares | June 30, 2026 |
| OSAIC HOLDINGS, INC. | $458,209 | 0.59% | 7,090 | Shares | June 30, 2026 |
| EXENCIAL WEALTH ADVISORS, LLC | $414,941 | 0.54% | 8,101 | Shares | Dec. 31, 2025 |
| INDEPENDENT FINANCIAL GROUP, LLC | $400,162 | 0.52% | 6,190 | Shares | June 30, 2026 |
| TWO SIGMA INVESTMENTS, LP | $387,900 | 0.50% | 6,000 | Shares | June 30, 2026 |
| Steward Partners Investment Advisory, LLC | $353,506 | 0.46% | 5,468 | Shares | June 30, 2026 |
| BlackDiamond Wealth Management, LLC | $341,104 | 0.44% | 5,082 | Shares | June 30, 2026 |
| Jaffetilchin Investment Partners, LLC | $339,791 | 0.44% | 6,492 | Shares | March 31, 2026 |
| Farther Finance Advisors, LLC | $321,828 | 0.42% | 4,978 | Shares | June 30, 2026 |
| Beacon Pointe Advisors, LLC | $319,953 | 0.42% | 4,949 | Shares | June 30, 2026 |
| Retirement Planning Co of New England, Inc. | $286,904 | 0.37% | 4,438 | Shares | June 30, 2026 |
| Intrepid Financial Planning Group LLC | $267,586 | 0.35% | 4,139 | Shares | June 30, 2026 |
| Fulcrum Equity Management | $263,395 | 0.34% | 4,074 | Shares | June 30, 2026 |
| Keystone Financial Group | $258,600 | 0.34% | 4,000 | Shares | June 30, 2026 |
| Ally Invest Advisors Inc. | $231,522 | 0.30% | 3,581 | Shares | June 30, 2026 |
| Cherry Creek Investment Advisors, Inc. | $222,849 | 0.29% | 3,447 | Shares | June 30, 2026 |
| CDKV HOLDINGS LLC | $166,797 | 0.22% | 2,580 | Shares | June 30, 2026 |
| AllSquare Wealth Management LLC | $81,293 | 0.11% | 2,092 | Shares | Sept. 30, 2025 |
| Ashton Thomas Private Wealth, LLC | $70,210 | 0.09% | 1,086 | Shares | June 30, 2026 |
| Rockefeller Capital Management L.P. | $66,901 | 0.09% | 1,034 | Shares | June 30, 2026 |
| US BANCORP \DE\ | $64,650 | 0.08% | 1,000 | Shares | June 30, 2026 |
| MGB Wealth Management, LLC | $51,220 | 0.07% | 1,000 | Shares | Dec. 31, 2025 |
| HARBOR INVESTMENT ADVISORY, LLC | $29,093 | 0.04% | 450 | Shares | June 30, 2026 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $18,319 | 0.02% | 350 | Shares | March 31, 2026 |
| PNC Financial Services Group, Inc. | $17,132 | 0.02% | 265 | Shares | June 30, 2026 |
| Arax Advisory Partners | $13,577 | 0.02% | 210 | Shares | June 30, 2026 |
| Axiom Investment Management LLC | $11,637 | 0.02% | 180 | Shares | June 30, 2026 |
| Aptus Capital Advisors, LLC | $11,637 | 0.02% | 180 | Shares | June 30, 2026 |
| Asset Dedication, LLC | $10,797 | 0.01% | 167 | Shares | June 30, 2026 |
| First Command Advisory Services, Inc. | $6,465 | 0.01% | 100 | Shares | June 30, 2026 |
| BANK OF MONTREAL /CAN/ | $6,465 | 0.01% | 100 | Shares | June 30, 2026 |
| Salomon & Ludwin, LLC | $6,335 | 0.01% | 100 | Shares | June 30, 2026 |
| Institute for Wealth Management, LLC. | $4,267 | 0.01% | 66 | Shares | June 30, 2026 |
| Global Retirement Partners, LLC | $3,879 | 0.01% | 60 | Shares | June 30, 2026 |
| Pinnacle Wealth Planning Services, Inc. | $3,814 | 0.00% | 59 | Shares | June 30, 2026 |
| Spire Wealth Management | $3,426 | 0.00% | 53 | Shares | June 30, 2026 |
| AE Wealth Management LLC | $970 | 0.00% | 15 | Shares | June 30, 2026 |
| CWM, LLC | $785 | 0.00% | 15 | Shares | March 31, 2026 |
| Triumph Capital Management | $646 | 0.00% | 10 | Shares | June 30, 2026 |
| Physician Wealth Advisors, Inc. | $640 | 0.00% | 10 | Shares | June 30, 2026 |
| Cambridge Investment Research Advisors, Inc. | $567 | 0.00% | 8,774 | Shares | June 30, 2026 |
| FIDUCIARY FINANCIAL ADVISORS | $268 | 0.00% | 4 | Shares | June 30, 2026 |
| Motiv8 Investments LLC | $3 | 0.00% | 60 | Shares | Dec. 31, 2025 |