ORACLE INVESTMENT MANAGEMENT INC
Portfolio value QoQ: +4.9% 13F does not disclose cash
Based on 13F long-equity holdings only (cash, bonds, shorts not disclosed)
Turnover Q4 2025: 8.34% Est. buys $13,679,704 · sells $16,068,943
Median holding: 1.0 quarters Tracked Q1 2025–Q4 2025 · 62.9% still held
Performance vs S&P 500
Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.
Sector breakdown
Full portfolio 22 positions
| Type | Streak | 8Q trend | |||||
|---|---|---|---|---|---|---|---|
| WGS | $115,058,099 | 68.51% | 884,654 | $19,174,455 | Down ×4 | ||
| ARDX | $10,917,398 | 6.50% | 1,872,624 | $2,631,317 | Up ×2 | ||
| BHVN | $8,717,923 | 5.19% | 772,181 | $-2,389,267 | Up ×3 | ||
| Unknown issuer (CUSIP: 87918A905) | $4,550,000 | 2.71% | 650,000 | Call option | $913,035 | Up ×1 | |
| Unknown issuer (CUSIP: 670002AD6) | $4,032,000 | 2.40% | 600,000 | Call option | Up ×1 | ||
| Unknown issuer (CUSIP: 039697907) | $3,498,000 | 2.08% | 600,000 | Call option | $11,272 | Down ×2 | |
| QDEL | $3,378,391 | 2.01% | 118,291 | $-105,279 | |||
| FORA | $2,896,147 | 1.72% | 1,366,107 | $-177,594 | |||
| PSNL | $2,701,170 | 1.61% | 339,343 | $1,205,254 | Up ×1 | ||
| Unknown issuer (CUSIP: G1110E907) | $2,629,441 | 1.57% | 232,900 | Call option | $-1,498,309 | Down ×1 | |
| TDOC | $2,480,366 | 1.48% | 354,338 | $-2,972,500 | Down ×1 | ||
| TSHA | $1,457,500 | 0.87% | 265,000 | Up ×1 | |||
| CAVA | $1,003,599 | 0.60% | 17,100 | $-29,412 | |||
| EWTX | $951,482 | 0.57% | 38,343 | Up ×1 | |||
| DAWN | $932,000 | 0.55% | 100,000 | Up ×1 | |||
| Unknown issuer (CUSIP: 717081903) | $622,500 | 0.37% | 25,000 | Call option | Up ×1 | ||
| ARKG | $564,915 | 0.34% | 19,500 | Up ×1 | |||
| SGMO | $435,012 | 0.26% | 1,035,742 | $-241,569 | Up ×1 | ||
| BIIB | $424,488 | 0.25% | 2,412 | $86,615 | |||
| TEM | $384,238 | 0.23% | 6,507 | Up ×1 | |||
| TSLA | $224,860 | 0.13% | 500 | $2,500 | |||
| HTZ | $77,100 | 0.05% | 15,000 | Up ×1 | |||
| No matches | |||||||
Conviction holdings
Positions increased for 3+ consecutive quarters.
Share counts are as reported in 13F filings (not split-adjusted)
| Security | Value | % of portfolio | Streak |
|---|---|---|---|
| BHVN | $8,717,923 | 5.19% | up ×3 |
Biggest new bets
New positions opened this quarter, largest first.
| Security | Value | Shares | % of portfolio |
|---|---|---|---|
| Unknown issuer (CUSIP: 670002AD6) | $4,032,000 | 600,000 | 2.40% |
| TSHA | $1,457,500 | 265,000 | 0.87% |
| EWTX | $951,482 | 38,343 | 0.57% |
| DAWN | $932,000 | 100,000 | 0.55% |
| Unknown issuer (CUSIP: 717081903) | $622,500 | 25,000 | 0.37% |
| ARKG | $564,915 | 19,500 | 0.34% |
| TEM | $384,238 | 6,507 | 0.23% |
| HTZ | $77,100 | 15,000 | 0.05% |
Top movers (QoQ)
| Security | Action | Shares Δ | Value Δ |
|---|---|---|---|
| WGS | Trimmed | -5K | +$19.2M |
| TDOC | Trimmed | -351K | -$3.0M |
| ARDX | Bought more | +369K | +$2.6M |
| BHVN | Bought more | +32K | -$2.4M |
| · | Trimmed | -42K | -$1.5M |
| PSNL | Bought more | +110K | +$1.2M |
| · | Bought more | +180K | +$913K |
| SGMO | Bought more | +31K | -$242K |
| FORA | Price move only | +0 | -$178K |
| QDEL | Price move only | +0 | -$105K |
Exited positions
Includes corporate events (mergers, delistings) — not all exits are sells
Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.
| Security | Quarter | Shares before | Value before | Price since exit |
|---|---|---|---|---|
| SWTX | June 30, 2025 | 531,351 | $23,448,520 | No longer tracked |
| PLTR | Dec. 31, 2025 | 29,500 | $5,381,390 | 10.7% |
| CNC | Dec. 31, 2025 | 110,300 | $3,935,504 | 70.5% |
| NVAX | Dec. 31, 2025 | 243,000 | $2,106,810 | 44.3% |
| KOID | Dec. 31, 2025 | 22,400 | $718,592 | |
| RXRX | June 30, 2025 | 120,000 | $634,800 | -26.9% |
| BDSX | Dec. 31, 2025 | 15,000 | $113,250 | 211.5% |