ORACLE INVESTMENT MANAGEMENT INC

CIK 1012622 · View on SEC EDGAR ↗

Portfolio value
$167.9M
#7,021 of 9,443 by 13F value · top 74.4%
Positions
22
As of
Dec. 31, 2025 Data as of Q4 2025

Portfolio value QoQ: +4.9% 13F does not disclose cash

Top 10 holdings weight
94.31%
Top 25 holdings weight
100.00%
Positions above 1%
11
Effective number of positions
2.1

Based on 13F long-equity holdings only (cash, bonds, shorts not disclosed)

Turnover Q4 2025: 8.34% Est. buys $13,679,704 · sells $16,068,943

Median holding: 1.0 quarters Tracked Q4 2024–Q4 2025 · 55.0% still held

New positions
8
Increased
5
Decreased
4
Closed
5
On this page

Performance vs S&P 500

Tracked Q2 2025–Q4 2025
+29.4%
S&P 500 total return (same window)
+11.9%
Excess return
+17.4%

Approximates a buy-and-hold portfolio built from quarterly SEC 13F snapshots. Excludes cash, short positions, options/derivatives, and non-13(f) securities — reflects the disclosed long-equity book only, not total fund AUM. SEC filing lag is up to 45 days; this is not a real-time-copyable timing.

Priceable coverage: 100.0% · Options excluded: 15.4%

Sector breakdown

Healthcare
89.8%
Consumer Discretionary
0.7%
Industrials
0.0%
Other/Unmapped
9.5%

Full portfolio 22 positions

Type Streak 8Q trend
WGS GeneDx Holdings Corp. - Class A Common Stock $115,058,099 68.51% 884,654 $19,174,455 Down ×4
ARDX Ardelyx, Inc. - Common Stock $10,917,398 6.50% 1,872,624 $2,631,317 Up ×2
BHVN Biohaven Ltd. Common Shares $8,717,923 5.19% 772,181 $-2,389,267 Up ×3
Unknown issuer (CUSIP: 87918A905) $4,550,000 2.71% 650,000 Call option $913,035 Up ×1
Unknown issuer (CUSIP: 670002AD6) $4,032,000 2.40% 600,000 Call option Up ×1
Unknown issuer (CUSIP: 039697907) $3,498,000 2.08% 600,000 Call option $11,272 Down ×2
QDEL QuidelOrtho Corporation - Common Stock $3,378,391 2.01% 118,291 $-105,279
FORA Forian Inc. - Common Stock $2,896,147 1.72% 1,366,107 $-177,594
PSNL Personalis, Inc. - Common Stock $2,701,170 1.61% 339,343 $1,205,254 Up ×1
Unknown issuer (CUSIP: G1110E907) $2,629,441 1.57% 232,900 Call option $-1,498,309 Down ×1
TDOC Teladoc Health, Inc. Common Stock $2,480,366 1.48% 354,338 $-2,972,500 Down ×1
TSHA Taysha Gene Therapies, Inc. - Common Stock $1,457,500 0.87% 265,000 Up ×1
CAVA CAVA Group, Inc. Common Stock $1,003,599 0.60% 17,100 $-29,412
EWTX Edgewise Therapeutics, Inc. - Common Stock $951,482 0.57% 38,343 Up ×1
DAWN Day One Biopharmaceuticals, Inc. - Common Stock $932,000 0.55% 100,000 Up ×1
Unknown issuer (CUSIP: 717081903) $622,500 0.37% 25,000 Call option Up ×1
ARKG $564,915 0.34% 19,500 Up ×1
SGMO Sangamo Therapeutics, Inc. - Common Stock $435,012 0.26% 1,035,742 $-241,569 Up ×1
BIIB Biogen Inc. - Common Stock $424,488 0.25% 2,412 $86,615
TEM Tempus AI, Inc. - Class A Common Stock $384,238 0.23% 6,507 Up ×1
TSLA Tesla, Inc. - Common Stock $224,860 0.13% 500 $2,500
HTZ Hertz Global Holdings, Inc - Common Stock $77,100 0.05% 15,000 Up ×1

Conviction holdings

Positions increased for 3+ consecutive quarters.

Share counts are as reported in 13F filings (not split-adjusted)

Security Value % of portfolio Streak
BHVN $8,717,923 5.19% up ×3

Biggest new bets

New positions opened this quarter, largest first.

Security Value Shares % of portfolio
Unknown issuer (CUSIP: 670002AD6) $4,032,000 600,000 2.40%
TSHA $1,457,500 265,000 0.87%
EWTX $951,482 38,343 0.57%
DAWN $932,000 100,000 0.55%
Unknown issuer (CUSIP: 717081903) $622,500 25,000 0.37%
ARKG $564,915 19,500 0.34%
TEM $384,238 6,507 0.23%
HTZ $77,100 15,000 0.05%

Top movers (QoQ)

Security Action Shares Δ Value Δ
WGS Trimmed -5K +$19.2M
TDOC Trimmed -351K -$3.0M
ARDX Bought more +369K +$2.6M
BHVN Bought more +32K -$2.4M
Trimmed -42K -$1.5M
PSNL Bought more +110K +$1.2M
Bought more +180K +$913K
SGMO Bought more +31K -$242K
FORA Price move only +0 -$178K
QDEL Price move only +0 -$105K

Exited positions

Includes corporate events (mergers, delistings) — not all exits are sells

Closed positions reflect 13F reporting changes; for index managers these are often mechanical (delisting, M&A, index rebalancing), not active decisions.

SecurityQuarter Shares before Value before Price since exit
SWTX June 30, 2025 531,351 $23,448,520 No longer tracked
PLTR Dec. 31, 2025 29,500 $5,381,390 -2.7%
BCRX March 31, 2025 535,558 $4,027,396 30.9%
CNC Dec. 31, 2025 110,300 $3,935,504 55.9%
NVAX Dec. 31, 2025 243,000 $2,106,810 31.6%
PHAT March 31, 2025 145,064 $1,177,920 38.9%
KOID Dec. 31, 2025 22,400 $718,592
RXRX June 30, 2025 120,000 $634,800 -32.9%
PACB March 31, 2025 279,638 $511,738 5.5%
EYPT March 31, 2025 32,500 $242,125 0.3%
BDSX Dec. 31, 2025 15,000 $113,250 259.3%