PHAT Phathom Pharmaceuticals, Inc. - Common Stock

NASDAQ · Pharmaceuticals · View on SEC EDGAR ↗
$9.67
Price · Aug 19, 2026
Fundamentals as of Jul 30, 2026

PHAT Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$9.67
Market Cap
$768M
P/E (TTM)
-3.5
EPS (TTM)
$-3.03
Revenue (TTM)
$175M
Div Yield
ROE
52.4%
Debt/Equity
-0.5
52W Range
$8 – $18

PHAT Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $175M
4-point trend, +175110000.00
2022-12-31 2025-12-31
EPS $-3.03
5-point trend, +22.1%
2021-12-31 2025-12-31
Free Cash Flow $-167M
7-point trend, -355.8%
2019-12-31 2025-12-31
Margins -126.4%
3-point trend, +15.3%
2023-12-31 2025-12-31

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
PHAT
Peer Median
P/E (TTM)
5-point trend, -8.3%
-3.5
11.7
P/S (TTM)
3-point trend, -99.1%
4.4
5.4
P/B
5-point trend, -132.5%
-1.8
3.7
EV / EBITDA
5-point trend, -110.7%
-5.3
Price / FCF
5-point trend, -76.1%
-4.6

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
PHAT
Peer Median
Gross Margin
3-point trend, +15.3%
87.1%
83.9%
Operating Margin
3-point trend, +99.6%
-91.4%
Net Profit Margin
3-point trend, +99.6%
-126.4%
-45.6%
ROA
5-point trend, -16.9%
-69.4%
-25.4%
ROE
5-point trend, +132.0%
52.4%
-27.1%
ROIC
69.8%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
PHAT
Peer Median
Debt / Equity
5-point trend, -138.4%
-0.5
Current Ratio
5-point trend, -82.4%
1.7
4.6
Quick Ratio
5-point trend, -83.7%
1.6

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
PHAT
Peer Median
Revenue YoY
4-point trend, +175110000.00
216.9%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
PHAT
Peer Median
EPS (Diluted)
5-point trend, +22.1%
$-3.03

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
PHAT
Peer Median

PHAT Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 17 analysts
  • Strong Buy 6 35.3%
  • Buy 9 52.9%
  • Hold 2 11.8%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

10 analysts · 2026-08-18
Median target $21.50 +122.3%
Mean target $21.50 +122.3%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.02%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.21 $-0.26 0.05%
March 31, 2026 $-0.37 $-0.33 -0.04%
Dec. 31, 2025 $-0.29 $-0.39 0.10%
Sept. 30, 2025 $-0.41 $-0.56 0.15%
June 30, 2025 $-1.05 $-1.06 0.01%
March 31, 2025 $-1.31 $-1.17 -0.14%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PHAT $1.18B -5.5 216.9% -126.4% 52.4% 87.1%
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
AMPH $1.22B 13.2 -1.7% 13.6% 12.7% 49.5%
ACRS $363M -5.7 -58.2% -829.6% -55.3%
SGP 50.0%
CRMD $922M 5.7 617.0% 52.3% 52.1% 88.5%
ARVN $753M -10.4 -0.30% -30.8% -15.5%
ZVRA $509M 6.6 350.9% 78.2% 61.2%
CTNM -5.3 -27.7%
EOLS $432M -8.3 11.6% -17.4% 247.3% 66.3%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 18
Annual Income Statement data for PHAT
Metric Trend 2025202420232022
Revenue 4-point trend, +175110000.00 $175M $55M $682.0K $0
Cost of Revenue 4-point trend, +22599000.00 $23M $8M $167.0K $0
Gross Profit 4-point trend, +152511000.00 $153M $47M $515.0K $0
R&D Expense 4-point trend, -54.1% $33M $34M $50M $71M
SG&A Expense 4-point trend, +177.0% $280M $291M $118M $101M
Operating Expenses 4-point trend, +81.2% $312M $325M $168M $172M
Operating Income 4-point trend, +7.2% $-160M $-277M $-167M $-172M
Interest Expense 2-point trend, +53.7% · · $42M $27M
Interest Income 4-point trend, +230.4% $7M $15M $8M $2M
Other Non-op 4-point trend, -72.7% $-190.0K $-8.0K $-188.0K $-110.0K
Pretax Income 2-point trend, +33.8% $-221M $-334M · ·
Income Tax Flat — no change across 4 periods $0 $0 $0 $0
Net Income 4-point trend, -11.9% $-221M $-334M $-202M $-198M
EPS (Basic) 4-point trend, +40.0% $-3.03 $-5.29 $-3.93 $-5.05
EPS (Diluted) 4-point trend, +40.0% $-3.03 $-5.29 $-3.93 $-5.05
Shares (Basic) 4-point trend, +86.4% 72,918,764 63,176,210 51,289,092 39,118,215
Shares (Diluted) 4-point trend, +86.4% 72,918,764 63,176,210 51,289,092 39,118,215
EBITDA 4-point trend, +7.3% $-159M $-277M $-167M $-172M
Balance Sheet 24
Annual Balance Sheet data for PHAT
Metric Trend 2025202420232022
Cash & Equivalents 4-point trend, -16.4% $130M $297M $381M $155M
Receivables 4-point trend, +78129000.00 $78M $39M $2M $0
Inventory 4-point trend, +5518000.00 $6M $3M $1M $0
Prepaid Expense 4-point trend, +199.5% $15M $21M $13M $5M
Current Assets 4-point trend, +42.7% $229M $360M $397M $161M
PP&E (Net) 4-point trend, -11.8% $1M $1M $2M $1M
PP&E (Gross) 4-point trend, +69.5% $5M $4M $4M $3M
Accum. Depreciation 4-point trend, +136.2% $3M $3M $2M $1M
Other Non-current Assets 4-point trend, +875.6% $3M $2M $2M $299.0K
Total Assets 4-point trend, +57.2% $259M $378M $414M $165M
Accounts Payable 4-point trend, -50.2% $5M $11M $13M $10M
Accrued Liabilities 4-point trend, +512.0% $90M $53M $17M $15M
Current Liabilities 4-point trend, +403.3% $132M $86M $39M $26M
Capital Leases 3-point trend, +88.1% $2M · $462.0K $1M
Other Non-current Liabilities 4-point trend, -46.7% $4M $12M $10M $8M
Total Liabilities 4-point trend, +191.0% $697M $632M $487M $240M
Long-term Debt 4-point trend, +119.5% $209M $201M $138M $95M
Total Debt 4-point trend, +119.5% $209M $201M $138M $95M
Common Stock 4-point trend, +100.0% $6.0K $6.0K $5.0K $3.0K
Retained Earnings 4-point trend, -104.1% $-1.48B $-1.26B $-929M $-727M
Treasury Stock Flat — no change across 4 periods $0 $0 $0 $0
Stockholders' Equity 4-point trend, -485.7% $-438M $-254M $-73M $-75M
Liabilities + Equity 4-point trend, +57.2% $259M $378M $414M $165M
Shares Outstanding 4-point trend, +72.2% 71,419,025 68,518,238 57,970,044 41,468,871
Cash Flow 12
Annual Cash Flow data for PHAT
Metric Trend 2025202420232022
D&A 4-point trend, +2.1% $633.0K $795.0K $575.0K $620.0K
Stock-based Comp 4-point trend, +19.0% $29M $24M $45M $24M
Other Non-cash 4-point trend, -5.0% $25M $43M $18M $26M
Operating Cash Flow 4-point trend, -13.8% $-167M $-267M $-138M $-147M
CapEx 4-point trend, -78.0% $229.0K $135.0K $2M $1M
Investing Cash Flow 4-point trend, +78.0% $-229.0K $-135.0K $-2M $-1M
Debt Issued 4-point trend, +0.00 $0 $59M $39M $0
Net Debt Issued 3-point trend, -100.0% $0 $59M $39M ·
Stock Issued · · $14M ·
Financing Cash Flow 4-point trend, -100.2% $-288.0K $183M $368M $120M
Net Change in Cash 4-point trend, -507.7% $-167M $-84M $228M $-28M
Free Cash Flow 4-point trend, -13.2% $-167M $-267M $-139M $-148M
Profitability 8
Annual Profitability data for PHAT
Metric Trend 2025202420232022
Gross Margin 3-point trend, +15.3% 87.1% 85.6% 75.5% ·
Operating Margin 3-point trend, +99.6% -91.4% -502.2% -24532.5% ·
Net Margin 3-point trend, +99.6% -126.4% -605.1% -29558.9% ·
Pretax Margin -126.4% · · ·
EBITDA Margin 3-point trend, +99.6% -91.0% -500.8% -24448.2% ·
ROA 4-point trend, +37.8% -69.4% -84.4% -69.7% -111.6%
ROE 4-point trend, -86.6% 52.4% 151.7% 445.4% 390.6%
ROIC 69.8% · · ·
Liquidity & Solvency 5
Annual Liquidity & Solvency data for PHAT
Metric Trend 2025202420232022
Current Ratio 4-point trend, -71.7% 1.7 4.2 10.2 6.1
Quick Ratio 4-point trend, -73.4% 1.6 3.9 9.9 5.9
Debt / Equity 4-point trend, +62.5% -0.5 -0.8 -1.9 -1.3
LT Debt / Equity 4-point trend, +62.5% -0.5 -0.8 -1.9 -1.3
Interest Coverage 2-point trend, +36.9% · · -4.0 -6.3
Efficiency 3
Annual Efficiency data for PHAT
Metric Trend 2025202420232022
Asset Turnover 3-point trend, +22791.7% 0.5 0.1 0.0 ·
Inventory Turnover 3-point trend, +1773.3% 5.2 3.6 0.3 ·
Receivables Turnover 3-point trend, +259.5% 3.0 2.7 0.8 ·
Per Share 5
Annual Per Share data for PHAT
Metric Trend 2025202420232022
Book Value / Share 4-point trend, -240.1% $-6.14 $-4.37 $-1.26 $-1.80
Revenue / Share 3-point trend, +17955.6% $2.40 $0.87 $0.01 ·
Cash Flow / Share 4-point trend, +38.9% $-2.29 $-4.22 $-2.68 $-3.75
Cash / Share 4-point trend, -51.4% $1.82 $5.13 $6.58 $3.75
EPS (TTM) 4-point trend, +40.0% $-3.03 $-5.29 $-3.93 $-5.05
Growth Rates 1
Annual Growth Rates data for PHAT
Metric Trend 2025202420232022
Revenue YoY 2-point trend, -97.3% 216.9% 8001.5% · ·
Valuation (TTM) 13
Annual Valuation (TTM) data for PHAT
Metric Trend 2025202420232022
Revenue TTM 4-point trend, +175110000.00 $175M $55M $682.0K $0
Net Income TTM 4-point trend, -11.9% $-221M $-334M $-202M $-198M
Market Cap 4-point trend, +154.7% $1.18B $471M $529M $465M
Enterprise Value 4-point trend, +212.0% $1.26B $375M $286M $405M
P/E 4-point trend, -146.4% -5.5 -1.5 -2.3 -2.2
P/S 3-point trend, -99.1% 6.8 8.5 776.1 ·
P/B 4-point trend, +56.5% -2.7 -1.9 -7.3 -6.2
P / Cash Flow 4-point trend, -123.7% -7.1 -1.8 -3.8 -3.2
P / FCF 4-point trend, -125.0% -7.1 -1.8 -3.8 -3.2
EV / EBITDA 4-point trend, -236.4% -7.9 -1.4 -1.7 -2.4
EV / FCF 4-point trend, -175.7% -7.6 -1.4 -2.1 -2.7
EV / Revenue 3-point trend, -98.3% 7.2 6.8 418.9 ·
Earnings Yield 4-point trend, +59.4% -18.3% -65.1% -43.0% -45.0%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $175M$55M$682.0K$0
Gross Margin % 87.1%85.6%75.5%
Operating Margin % -91.4%-502.2%-24532.5%
Net Income $-221M$-334M$-202M$-198M$-144M
Diluted EPS $-3.03$-5.29$-3.93$-5.05$-3.89
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity -0.5-0.8-1.9-1.31.2
Current Ratio 1.74.210.26.19.9
Quick Ratio 1.63.99.95.99.7
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-167M$-267M$-139M$-148M$-149M

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Institutional owners (13F) 178 filers · $617.3M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
33 (+1 vs prior Q) 30 (-5 vs prior Q) 51 (-22 vs prior Q) 50 (+13 vs prior Q) +3.2M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Frazier Life Sciences Management, L.P. $135,261,406 12,466,489 21.91% Shares
Medicxi Ventures Management (Jersey) Ltd $80,990,606 7,464,572 13.12% Shares
Carlyle Group Inc. $37,940,367 3,496,808 6.15% Shares
MILLENNIUM MANAGEMENT LLC $36,627,799 3,375,834 5.93% Shares
VANGUARD CAPITAL MANAGEMENT LLC $28,827,842 2,656,944 4.67% Shares
NEA Management Company, LLC $21,267,834 1,960,169 3.45% Shares
683 Capital Management, LLC $20,072,501 1,850,000 3.25% Shares
STATE STREET CORP $17,211,605 1,586,323 2.79% Shares
Catalys Pacific, LLC $16,208,316 1,493,854 2.63% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $15,871,000 1,462,738 2.57% Shares
GOLDMAN SACHS GROUP INC $15,552,303 1,433,392 2.52% Shares
WASATCH ADVISORS LP $14,897,577 1,340,916 2.41% Shares
GEODE CAPITAL MANAGEMENT, LLC $12,271,034 1,130,751 1.99% Shares
Ensign Peak Advisors, Inc $11,413,256 1,051,913 1.85% Shares
Propel Bio Management, LLC $11,396,384 1,050,358 1.85% Shares
Point72 Asset Management, L.P. $11,090,794 1,022,193 1.80% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $8,643,446 796,631 1.40% Shares
SummitTX Capital, L.P. $8,566,618 789,550 1.39% Shares
EcoR1 Capital, LLC $6,781,250 625,000 1.10% Shares
PERCEPTIVE ADVISORS LLC $5,772,200 532,000 0.94% Shares
TWO SIGMA INVESTMENTS, LP $5,631,975 519,076 0.91% Shares
CITADEL ADVISORS LLC $5,216,680 480,800 0.85% Call option
VANGUARD GROUP INC $4,969,501 299,548 0.81% Shares
StepStone Group LP $4,689,364 422,085 0.76% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4,547,170 419,094 0.74% Shares
Woodline Partners LP $4,004,214 369,052 0.65% Shares
VANGUARD FIDUCIARY TRUST CO $3,847,117 354,573 0.62% Shares
AMERIPRISE FINANCIAL INC $3,189,358 293,950 0.52% Shares
Simplify Asset Management Inc. $2,704,547 249,267 0.44% Shares
JPMORGAN CHASE & CO $2,616,050 240,667 0.42% Shares
RENAISSANCE TECHNOLOGIES LLC $2,456,440 226,400 0.40% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $2,281,755 210,300 0.37% Call option
NewEdge Advisors, LLC $2,212,988 203,962 0.36% Shares
Avidity Partners Management LP $2,170,000 200,000 0.35% Shares
Jump Financial, LLC $2,081,746 191,866 0.34% Shares
Opaleye Management Inc. $2,013,641 185,589 0.33% Shares
CITADEL ADVISORS LLC $2,006,176 184,901 0.32% Shares
Trexquant Investment LP $1,886,641 173,884 0.31% Shares
Jones Hill Capital LP $1,752,123 161,486 0.28% Shares
MARSHALL WACE, LLP $1,751,191 161,400 0.28% Shares
XTX Topco Ltd $1,473,777 135,832 0.24% Shares
DIADEMA PARTNERS LP $1,409,958 129,950 0.23% Shares
SIG BROKERAGE, LP $1,345,400 124,000 0.22% Call option
Engineers Gate Manager LP $1,283,088 118,257 0.21% Shares
Virtus Investment Advisers, LLC $1,216,708 112,139 0.20% Shares
BANK OF AMERICA CORP /DE/ $1,178,885 108,653 0.19% Shares
SCHRODER INVESTMENT MANAGEMENT GROUP $1,105,968 101,745 0.18% Shares
JANE STREET GROUP, LLC $1,096,761 101,084 0.18% Shares
Stratos Wealth Partners, LTD. $1,085,000 100,000 0.18% Shares
Swiss National Bank $1,071,980 98,800 0.17% Shares
GILDER GAGNON HOWE & CO LLC $956,254 88,134 0.15% Shares
Stonepine Capital Management, LLC $922,358 85,010 0.15% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $838,879 77,316 0.14% Shares
JANE STREET GROUP, LLC $837,620 77,200 0.14% Call option
BlackRock, Inc. $835,548 77,009 0.14% Shares
Campbell & CO Investment Adviser LLC $746,035 68,759 0.12% Shares
Penn Mutual Asset Management $681,402 62,802 0.11% Shares
STATE OF WISCONSIN INVESTMENT BOARD $675,771 62,283 0.11% Shares
RHUMBLINE ADVISERS $654,740 60,346 0.11% Shares
UBS Group AG $635,105 58,535 0.10% Shares
Birchview Capital, LP $596,750 55,000 0.10% Shares
D. E. Shaw & Co., Inc. $585,206 53,936 0.09% Shares
ALLIANCEBERNSTEIN L.P. $547,612 49,290 0.09% Shares
CITIGROUP INC $543,661 50,107 0.09% Shares
Bank of New York Mellon Corp $540,037 49,773 0.09% Shares
Pale Fire Capital SE $539,386 49,713 0.09% Shares
NOMURA HOLDINGS INC $532,735 49,100 0.09% Put option
Man Group plc $528,167 48,679 0.09% Shares
AlphaQuest LLC $468,668 28,250 0.08% Shares
ADAR1 Capital Management, LLC $465,465 42,900 0.08% Shares
Quantbot Technologies LP $463,892 42,755 0.08% Shares
WELLINGTON MANAGEMENT GROUP LLP $459,866 42,384 0.07% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $446,866 40,222 0.07% Shares
BARCLAYS PLC $435,660 40,153 0.07% Shares
NOMURA HOLDINGS INC $434,000 40,000 0.07% Shares
Y-Intercept (Hong Kong) Ltd $432,318 39,845 0.07% Shares
Fiduciary Trust Co $387,681 35,731 0.06% Shares
Nebula Research & Development LLC $363,816 37,937 0.06% Shares
Persistent Asset Partners Ltd $359,753 33,157 0.06% Shares
ALLSTATE CORP $356,694 32,875 0.06% Shares
Squarepoint Ops LLC $342,806 31,595 0.06% Shares
CITADEL ADVISORS LLC $337,435 31,100 0.05% Put option
VANGUARD ASSET MANAGEMENT, Ltd $309,290 28,506 0.05% Shares
MetLife Investment Management, LLC $304,961 28,107 0.05% Shares
Kera Capital Partners, Inc. $291,062 26,826 0.05% Shares
Zurcher Kantonalbank (Zurich Cantonalbank) $280,342 25,838 0.05% Shares
Caption Management, LLC $260,400 24,000 0.04% Call option
Caption Management, LLC $260,400 24,000 0.04% Put option
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $245,720 22,647 0.04% Shares
COMMONWEALTH EQUITY SERVICES, LLC $244,500 22,535 0.04% Shares
Summit Financial Wealth Advisors, LLC $240,252 22,143 0.04% Shares
JANUS HENDERSON GROUP PLC $239,403 21,500 0.04% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $236,198 18,731 0.04% Shares
Vanguard Global Advisers, LLC $225,344 20,769 0.04% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $220,255 20,300 0.04% Put option
Invesco Ltd. $211,065 19,453 0.03% Shares
INSPIRION WEALTH ADVISORS, LLC $209,794 19,914 0.03% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $192,316 17,725 0.03% Shares
State of Wyoming $191,383 17,639 0.03% Shares
PROFUND ADVISORS LLC $187,455 17,277 0.03% Shares

Company insiders 20 insiders · 9 officers · 12 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Steven L Basta President and CEO Feb. 10, 2026 F 373,315 0 0 $0
Molly Henderson CFO and CBO April 7, 2025 S 89,868 0 0 $0
Todd P. Branning Chief Financial Officer Jan. 28, 2021 A 0 0 $0
Terrie Curran President and Chief Executive Feb. 27, 2025 A 360,465 0 0 $0
Azmi Nabulsi Chief Operating Officer Feb. 27, 2025 A 312,590 0 0 $0
Robert Charles Breedlove Principal Accounting Officer July 14, 2026 F 59,925 0 2 $-12,652
Anne Marie Cook Chief Legal Off. & Corp. Sec. Feb. 10, 2026 F 88,660 0 0 $0
Sanjeev Narula Chief Financial & Bus. Officer Jan. 2, 2026 A 226,715 0 0 $0
Anthony J. Guzzo VP, Chief Accounting Officer Jan. 19, 2022 A 8,399 0 0 $0
Asit Parikh Director May 22, 2026 G 148,500 0 0 $0
Mark Stenhouse Director May 19, 2026 A 54,122 0 0 $0
Theodore R Schroeder Director May 19, 2026 A 45,122 0 0 $0
James N. Topper Director May 19, 2026 A 66,718 0 0 $0
Frank Karbe Director May 19, 2026 A 91,622 0 0 $0
Michael F Cola Director May 19, 2026 A 63,920 0 0 $0
Heidi Kunz Director May 19, 2026 A 54,122 0 0 $0
David A Socks Director May 23, 2024 A 19,500 0 0 $0
Tadataka Yamada Director May 21, 2021 A 0 0 $0
Jonathan S. Edwards Director Oct. 29, 2019 C 47,984 0 0 $0
Takeda Pharmaceutical Company Limited Jan. 24, 2024 S 3,755,583 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 5 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Frazier Life Sciences Public Fund, L.P., FHMLSP, L.P., FHMLSP, L.L.C., Frazier Life Sciences X, L.P., FHMLS X, L.P., FHMLS X, L.L.C., Frazier Life Sciences XI, L.P., FHMLS XI, L.P., FHMLS XI, L.L.C., Frazier Life Sciences IX, L.P., FHMLS IX, L.P., FHMLS IX, L.L.C., Frazier Life Sciences XII, L.P., FHMLS XII, L.P., FHMLS XII, L.L.C., James N. Topper, Patrick J. Heron ×3 filings Nov. 4, 2025 8.60% Amendment SEC
Frazier Life Sciences IX, L.P., FHMLS IX, L.P., FHMLS IX, L.L.C., Frazier Life Sciences Public Fund, L.P., FHMLSP, L.P., FHMLSP, L.L.C., Frazier Life Sciences Public Overage Fund, L.P., FHMLSP Overage, L.P., FHMLSP Overage, L.L.C., Frazier Life Sciences XI, L.P., FHMLS XI, L.P., FHMLS XI, L.L.C., James N. Topper, Patrick J. Heron, Albert Cha, James Brush, Daniel Estes ×8 filings Aug. 22, 2024 Initial filing SEC
Takeda Pharmaceutical Company Limited ×3 filings April 10, 2024 Initial filing SEC
Frazier Life Sciences IX, L.P ., FHMLS IX, L.P., FHMLS IX, L.L.C., Frazier Life Sciences Public Fund, L.P., FHMLSP, L.P., FHMLSP, L.L.C., Frazier Life Sciences Public Overage Fund, L.P., FHMLSP Overage, L.P., FHMLSP Overage, L.L.C., Frazier Life Sciences XI, L.P., FHMLS XI, L.P., FHMLS XI, L.L.C., James N. Topper, Patrick J. Heron, Albert Cha, James Brush, Daniel Estes May 26, 2023 Initial filing SEC
S.S. OR ×5 filings Nov. 12, 2021 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 34 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
BBP · ETFis Series Trust I 1.23% 64,997 NS April 30, 2026 N-PORT
PILL · Direxion Shares ETF Trust 1.01% 11,659 NS April 30, 2026 N-PORT
IHE · iShares Trust 0.09% 182,732 SH Aug. 8, 2026 Daily
IWC · iShares Trust 0.09% 166,627 SH Aug. 8, 2026 Daily
GSSC · Goldman Sachs ETF Trust 0.05% 49,552 NS May 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.05% 4,339 SH Aug. 8, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.04% 78,352 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.04% 2,912 NS May 31, 2026 N-PORT
IBB · iShares Trust 0.04% 414,853 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.02% 283,184 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.02% 30,521 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.02% 329,427 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.02% 20,112 NS April 30, 2026 N-PORT
ISCG · iShares Trust 0.02% 18,573 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.01% 1,253,335 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.01% 2,182 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.01% 586,438 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 15,003 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 148,237 SH Aug. 8, 2026 Daily
SCHA · SCHWAB STRATEGIC TRUST 0.01% 236,650 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.01% 21,971 NS April 30, 2026 N-PORT
ISCB · iShares Trust 0.01% 2,641 SH Aug. 8, 2026 Daily
IWO · iShares Trust 0.01% 129,591 SH Aug. 8, 2026 Daily
UWM · ProShares Trust 0.01% 1,707 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 1,727 NS May 31, 2026 N-PORT
WSML · iShares Trust 0.00% 2,570 SH Aug. 8, 2026 Daily
HDG · ProShares Trust 0.00% 43 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 1,333 NS May 31, 2026 N-PORT
AVUQ · AMERICAN CENTURY ETF TRUST 0.00% 205 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 79,259 SH Aug. 8, 2026 Daily
SCHB · SCHWAB STRATEGIC TRUST 0.00% 33,490 NS May 31, 2026 N-PORT
IWV · iShares Trust 0.00% 9,288 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 2,007,668 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 3,478 SH Aug. 8, 2026 Daily