PACB Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $2.54
Market Cap (MRQ) $789M
P/E (TTM) -6.2
EPS (TTM) $-0.41
Revenue (TTM) $159M
ROE (TTM) -929.3%
52W Range $1–$3

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04
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About Pacific Biosciences of California, Inc. - Common Stock Company overview from Wikipedia

05 · wikidata

Pacific Biosciences of California, Inc. (a.k.a. PacBio) is an American biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation. PacBio has two principal sequencing platforms: single-molecule real-time sequencing (SMRT), based on the properties of zero-mode waveguides and sequencing by binding (SBB) chemistry, which uses native nucleotides and scarless incorporation for DNA binding and extension.

History

The company was founded based on research done at Cornell University that combined semiconductor processing and photonics with biotechnology research. Three graduate students in the lab of Professors Watt W. Webb — Jonas Korlach — and Harold Craighead — Steve Turner and Mathieu Foquet — became the first employees.

It began under the name Nanofluidics, Inc. The company raised nearly US$400,000,000 in six rounds of primarily venture capital financing, making it one of the most capitalized startups in 2010 leading up to their public offering in October of that year. Key investors included Mohr Davidow Ventures, Kleiner, Perkins, Caufield & Byers, Alloy Ventures, and Wellcome Trust.

The company's first commercial product, the PacBio RS, was sold to a limited set of customers in 2010 and was commercially released in early 2011. A subsequent version of the sequencer called the PacBio RS II was released in April 2013.

Leadership

In 2004, Kleiner Perkins entrepreneur-in-residence Hugh Martin became CEO. On 6 January 2012 board member Michael Hunkapiller, PhD assumed the role of CEO. Hunkapiller retired in September 2020, and was replaced by chairman of the board Christian Henry. Henry was a former executive VP and chief commercial officer of Illumina before joining the board at PacBio in July 2018.

Illumina: attempted acquisition

On 1 November 2018, Illumina, Inc. agreed to purchase PacBio for US$1.2 billion in cash. The deal was expected to close in the fourth quarter of 2019. In December 2019, the Federal Trade Commission sued to block the acquisition. The deal was abandoned with an announcement on 2 January 2020. Illumina further agreed to pay Pacific Biosciences a $98 million US termination fee plus previously agreed upon deal extension payments of $22 million US in February and $6 million US in March 2020.

Sequencing technology

Sequencing instruments

The company's first scientific instrument, called the PacBio RS, was released to a limited set of customers in late 2010., with full commercial release in early 2011. Sequencing provider GATC Biotech was selected by Pacific Biosciences as its first European service provider in late 2010. A new version of the sequencer was released in April 2013 it produced longer sequence reads and higher throughput than the original RS instrument. The RS instrument will officially be supported until the end of 2021. In September 2015, the company released a new sequencing instrument, the Sequel System, with increased sequencing capacity at a smaller size and lower price compared to the PacBio RS II. Subsequently, in October 2022, PacBio launched a new sequencing system, which can sequence 1,300 human genomes per year as compared to 86 per year of the previous PacBio sequencing machines.

Reagents and SMRT Cells

To use either instrument, customers must also purchase reagent packs for DNA preparation and sequencing and small consumables called "SMRT Cells." Cells for early forms of the sequencer are slightly less than one-centimeter square and contains tens of thousands of zero-mode waveguides, whereas newer systems have a higher density of cells and contain 25 million zero-mode waveguides (ZMWGs), allowing for faster DNA sequencing.

Software and applications

Their secondary analysis bioinformatics product for the RS, called “SMRT Analysis”, was open source. For the Sequel system the secondary analysis software was reorganized as the "SMRT Link" application. In 2013, the company released new bioinformatics tools for automated genome assembly (HGAP) and finishing (Quiver).

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

sectorHealthcare industryLife Sciences Tools & Services employees485 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$160M
2016-12-31 → 2025-12-31
EPS$-1.82
2018-12-31 → 2025-12-31
Free Cash Flow$-114M
2016-12-31 → 2025-12-31
Net margin-82.5%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend PACB 5Y avg Peer Median Verdict
P/E (TTM) -6.25Y avg ≈-7.8 ≈-7.8 · ·
P/S (TTM) 5.05Y avg ≈13.8 ≈13.8 4.6 Undervalued
P/B (MRQ) -23.85Y avg ≈23.9 ≈23.9 · ·
Price / FCF (TTM) -6.45Y avg ≈-12.5 ≈-12.5 · ·
Price / Cash Flow (TTM) -6.75Y avg ≈-13.1 ≈-13.1 · ·
Price / Tangible Book (MRQ) -17.1 · · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -97.7%
Next Report Nov 03, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 3, 2026 $-0.14 $-0.13 -7.9%
March 31, 2026 $-0.12 $-0.14 12.7%
Dec. 31, 2025 $-0.12 $-0.15 20.3%
Sept. 30, 2025 $-0.13 $-0.15 16.1%
June 30, 2025 $-0.14 $-0.17 19.3%
March 31, 2025 $-1.44 $-0.19 -646.9%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 17
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $160M$154M$201M$128M$131M$79M$91M$79M$93M$91M$93M$61M
Cost of Revenue $114M$117M$148M$79M$72M$46M$56M$54M$59M$47M$39M$37M
Gross Profit $46M$37M$53M$49M$59M$33M$35M$25M$35M$44M$53M$23M
R&D Expense $97M$135M$187M$193M$113M$64M$60M$63M$65M$68M$60M$48M
SG&A Expense $141M$175M$170M$161M$124M$73M$75M$63M$59M$48M$45M$38M
Operating Expenses $600M$512M$387M$356M$269M$137M$135M$126M$124M$115M$83M$86M
Operating Income $-554M$-474M$-334M$-307M$-210M$-104M$-101M$-101M$-90M$-71M$-29M$-63M
Interest Expense ··$14M$15M$13M$267.0K$3M$2M$3M$3M$3M$3M
Other Non-op $15M$24M$33M$8M$93.0K$2M$1M$848.0K$516.0K$103.0K$364.0K$-478.0K
Pretax Income $-546M$-310M$-318M$-314M$-275M$29M$-84M·····
Income Tax $318.0K$316.0K$-11M$0$-94M·······
Net Income $-546M$-310M$-307M$-314M$-181M$29M$-84M$-103M$-92M$-74M$-32M$-66M
EPS (Basic) $-1.82$-1.13$-1.21$-1.40$-0.89$0.18$-0.55$-0.76····
EPS (Diluted) $-1.82$-1.59$-1.21$-1.40$-0.89$0.17$-0.55$-0.76····
Shares (Basic) 299,959,000274,488,000253,629,000224,550,000204,136,000165,187,000152,527,000135,094,000····
Shares (Diluted) 299,959,000288,366,000253,629,000224,550,000204,136,000174,970,000152,527,000135,094,000····
EBITDA $-554M$-474M$-334M$-307M$-210M$-104M$-101M$-94M$-81M$-67M$-25M$-59M
Balance Sheet 30
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $64M$55M$180M$325M$461M$82M$30M$19M$17M$17M$34M$36M
Short-term Investments $216M$335M$452M$447M$584M$237M$19M$84M$46M$55M$49M$65M
Receivables $35M$28M$37M$19M$24M$17M$15M$9M$13M$11M$5M$3M
Inventory $49M$59M$57M$50M$25M$14M$13M$18M$23M$16M$11M$11M
Prepaid Expense $11M$19M$17M$10M$7M$5M$3M$3M$2M$10M$12M$2M
Other Current Assets ········$931.0K$476.0K$741.0K$107.0K
Current Assets $375M$496M$742M$852M$1.10B$356M$81M$132M$102M$109M$111M$118M
PP&E (Net) $24M$31M$36M$42M$33M$25M$30M$34M$38M$15M$9M$7M
PP&E (Gross) $117M$112M$111M$107M$89M$75M$74M$71M$70M$52M$42M$37M
Accum. Depreciation $92M$82M$75M$65M$56M$50M$44M$37M$32M$37M$34M$30M
Goodwill $318M$318M$462M$410M$410M·······
Intangibles $15M$390M$457M$410M$411M·······
Other Non-current Assets $9M$9M$13M$11M$1M$43.0K$42.0K$43.0K$45.0K$10M$8M$29.0K
Total Assets $784M$1.26B$1.75B$1.77B$2.01B$414M$148M$170M$144M$138M$131M$124M
Accounts Payable $21M$17M$15M$12M$11M$4M$8M$7M$9M$8M$5M$6M
Accrued Liabilities $34M$23M$46M$33M$36M$17M$13M$13M$13M$17M$16M$11M
Short-term Debt ·$0$490.0K$2M$2M·$16M·····
Current Liabilities $73M$66M$95M$263M$72M$39M$49M$27M$29M$34M$38M$31M
Capital Leases $57M$15M$32M$41M$50M$38M$42M····$2M
Other Non-current Liabilities $0$546.0K$751.0K$1M$3M$752.0K···$2M$1M$2M
Total Liabilities $779M$754M$1.04B$1.20B$1.22B$78M$93M$56M$58M$53M$58M$69M
Long-term Debt ···$897M$896M·$16M$15M$14M$16M·$14M
Total Debt ·$0$490.0K$2M$2M·$16M·····
Common Stock $302.0K$294.0K$268.0K$227.0K$221.0K$192.0K$153.0K$150.0K$116.0K$93.0K$80.0K$74.0K
Paid-in Capital $2.70B$2.65B$2.54B$2.10B$2.01B$1.37B$1.12B$1.10B$966M$872M$787M$736M
Retained Earnings $-2.70B$-2.15B$-1.84B$-1.53B$-1.22B$-1.04B$-1.07B$-982M$-880M$-788M$-713M$-681M
AOCI $457.0K$422.0K$219.0K$-5M$-1M$85.0K$5.0K$-36.0K$-32.0K$5.0K$-7.0K$9.0K
Stockholders' Equity $5M$507M$701M$563M$791M$335M$55M$114M$86M$85M$74M$55M
Liabilities + Equity $784M$1.26B$1.75B$1.77B$2.01B$414M$148M$170M$144M$138M$131M$124M
Shares Outstanding 301,956,000294,418,000267,744,000226,505,000220,978,000192,294,000153,119,000150,244,000116,277,00092,677,00079,983,00073,927,000
Cash Flow 16
Metric Trend 202520242023202220212020201920182017201620152014
D&A ·······$7M$8M$4M$4M$4M
Stock-based Comp $42M$71M$72M$79M$73M$18M$16M$23M$20M$20M$14M$10M
Deferred Tax $-546.0K$-205.0K$-11M$0$-94M·······
Amort. of Intangibles $369M$27M$8M$913.0K$0$0$0·····
Restructuring ·$13M··········
Other Non-cash ·······$6M$-4M$-17M$-34M$528.0K
Operating Cash Flow $-111M$-206M$-259M$-263M$-111M$20M$-78M$-66M$-68M$-68M$-48M$-51M
CapEx $3M$6M$9M$17M$6M$1M$3M$2M$10M$8M$3M$2M
Investing Cash Flow $115M$124M$5M$116M$-679M$-219M$62M$-38M$-2M$-15M··
Stock Issued $0$0$189M$0$32M$46M$9M$10M$9M$8M$7M$4M
Net Stock Activity $0$0$15M$11M$32M$46M$9M$10M$9M$8M$7M$4M
Financing Cash Flow $3M$-43M$109M$10M$1.17B$252M$27M$107M$69M$66M··
Net Change in Cash $8M$-125M$-146M$-138M$380M···$-258.0K$-17M$-3M$10M
Taxes Paid $481.0K$256.0K$140.0K·········
Free Cash Flow $-114M$-212M$-268M$-280M$-117M$18M$-81M$-68M$-78M$-76M$-51M$-53M
Levered FCF ··$-282M·$-125M·······
Profitability 8
Metric Trend 202520242023202220212020201920182017201620152014
Gross Margin 28.6%24.2%26.3%38.2%45.1%41.3%38.0%31.9%37.1%48.7%57.6%38.6%
Operating Margin -346.1%-308.0%-166.8%-239.4%-161.2%-132.3%-110.6%-128.4%-96.1%-78.5%-31.4%-103.7%
Net Margin -341.5%-201.2%-153.0%-244.9%-138.8%37.3%-92.6%-130.4%-98.6%-82.0%-34.2%-109.2%
Pretax Margin -341.3%-201.0%-158.7%-244.9%-210.6%·······
EBITDA Margin -346.1%-308.0%-166.8%-239.4%-161.2%-132.3%-110.6%-119.3%-87.0%-74.3%-27.4%-96.8%
ROA -53.4%-20.6%-17.5%-16.7%-15.0%10.5%-52.9%-65.2%-65.4%-55.3%-24.8%-50.7%
ROE -1634.9%-64.6%-41.9%-52.8%-22.2%12.7%-158.8%-83.4%-108.0%-94.0%-49.3%-106.6%
ROIC -10360.5%-93.7%-46.0%·-17.5%·······
Liquidity & Solvency 4
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 5.17.57.83.215.49.21.64.93.53.22.93.7
Quick Ratio 4.36.37.03.014.98.71.34.12.72.52.33.3
Debt / Equity ·0.00.00.00.0·0.3·····
Interest Coverage ··-23.3-20.9-16.8-391.0-38.5-41.7-30.7-22.0-10.0-22.2
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.20.10.10.10.10.30.60.50.70.70.70.5
Inventory Turnover 2.12.02.82.13.73.43.62.63.03.53.53.5
Receivables Turnover 5.14.87.26.06.44.97.67.17.510.921.419.7
Per Share 6
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $0.02$1.72$2.62$2.49$3.58$1.74$0.36$0.76$0.74$0.91$0.92$0.74
Revenue / Share $0.53$0.53$0.79$0.57$0.64$0.45······
Cash Flow / Share $-0.37$-0.71$-1.02$-1.17$-0.54$0.11······
Cash / Share $0.21$0.19$0.67$1.44$2.08$0.42$0.19$0.13$0.14$0.18$0.42$0.49
Dividend / Share $0.00$0.00$0.00$0.00$0.00$0.00$0.00$0.00$0.00$0.00$0.00$0.00
EPS (TTM) $-1.82$-1.59$-1.21$-1.40$-0.89$0.17$-0.55$-0.76····
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 3.9%-23.2%56.3%-1.7%65.4%·······
Revenue CAGR 3Y 7.6%5.7%36.5%·········
Revenue CAGR 5Y 15.2%···········
Valuation (TTM) 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $160M$154M$201M$128M$131M$79M$91M$79M$93M$91M$93M$61M
Net Income TTM $-546M$-310M$-307M$-314M$-181M$29M$-84M$-103M$-92M$-74M$-32M$-66M
Market Cap $565M$539M$2.63B$1.85B$4.52B$4.99B$787M$1.11B$307M$352M$1.05B$580M
Enterprise Value ·$149M$2.00B$1.08B$3.48B·$754M·····
P/E -1.0-1.2-8.1-5.8-23.0152.6-9.3-9.7····
P/S 3.53.513.114.434.663.28.714.13.33.911.39.6
P/B 105.61.13.73.35.714.914.39.73.64.214.310.5
P / Tangible Book ·····14.9······
P / Cash Flow -5.1-2.6-10.1-7.0-40.7255.8-10.0-16.7-4.5-5.2-21.9-11.3
P / FCF -5.0-2.5-9.8-6.6-38.6270.2-9.7-16.3-3.9-4.6-20.6-10.9
EV / EBITDA ·-0.3-6.0-3.5-16.5·-7.5·····
EV / FCF ·-0.7-7.4-3.9-29.7·-9.3·····
EV / Revenue ·1.010.08.426.7·8.3·····
Earnings Yield -97.3%-86.9%-12.3%-17.1%-4.3%0.66%-10.7%-10.3%····

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $160M $154M $201M $128M $131M
Gross Margin % 28.6% 24.2% 26.3% 38.2% 45.1%
Operating Margin % -346.1% -308.0% -166.8% -239.4% -161.2%
Net Income $-546M $-310M $-307M $-314M $-181M
Diluted EPS $-1.82 $-1.59 $-1.21 $-1.40 $-0.89

Institutional owners (13F) 244 filers · $360.0M total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 244
Value held $360.0M
New positions 24
Exited positions 28
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
24 (-30 vs prior Q) 28 (-2 vs prior Q) 72 (+14 vs prior Q) 80 (+4 vs prior Q) +4.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BlackRock, Inc. $54,330,444 32,339,550 15.09% Shares
ARK Investment Management LLC $50,032,778 29,781,416 13.90% Shares
SOFTBANK GROUP CORP. $34,358,638 20,451,570 9.54% Shares
VANGUARD GROUP INC $31,859,776 17,037,314 8.85% Shares
VANGUARD CAPITAL MANAGEMENT LLC $22,508,529 13,397,934 6.25% Shares
GEODE CAPITAL MANAGEMENT, LLC $12,782,429 7,606,518 3.55% Shares
Sumitomo Mitsui Trust Group, Inc. $10,096,321 6,009,715 2.80% Shares
Amova Asset Management Americas, Inc. $10,036,224 6,009,715 2.79% Shares
STATE STREET CORP $10,014,774 5,961,175 2.78% Shares
Point72 Asset Management, L.P. $8,042,664 4,787,300 2.23% Shares
TWO SIGMA INVESTMENTS, LP $7,127,566 4,242,599 1.98% Shares
D. E. Shaw & Co., Inc. $7,069,686 4,208,146 1.96% Shares
MILLENNIUM MANAGEMENT LLC $6,656,903 3,962,442 1.85% Shares
Point72 (DIFC) Ltd $5,465,775 4,270,137 1.52% Shares
GOLDMAN SACHS GROUP INC $5,426,210 3,229,887 1.51% Shares
CITADEL ADVISORS LLC $4,781,117 2,845,903 1.33% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $4,488,819 2,671,916 1.25% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4,455,861 2,652,298 1.24% Shares
NORTHERN TRUST CORP $3,952,681 2,352,786 1.10% Shares
VANGUARD FIDUCIARY TRUST CO $3,675,213 2,187,627 1.02% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $3,577,162 2,129,263 0.99% Shares
Longaeva Partners L.P. $3,558,628 2,118,231 0.99% Shares
IQ EQ FUND MANAGEMENT (IRELAND) Ltd $2,846,837 1,694,546 0.79% Shares
Birchview Capital, LP $2,268,000 1,350,000 0.63% Shares
BANK OF AMERICA CORP /DE/ $2,264,860 1,348,131 0.63% Shares
Invesco Ltd. $2,179,114 1,297,091 0.61% Shares
AQR CAPITAL MANAGEMENT LLC $2,178,430 1,296,684 0.61% Shares
Nuveen, LLC $1,718,830 1,023,113 0.48% Shares
RENAISSANCE TECHNOLOGIES LLC $1,623,216 966,200 0.45% Shares
BOURNE LENT ASSET MANAGEMENT INC $1,584,332 943,055 0.44% Shares
TWO SIGMA ADVISERS, LP $1,547,425 827,500 0.43% Shares
HHLR ADVISORS, LTD. $1,543,739 918,892 0.43% Shares
UBS Group AG $1,500,475 893,140 0.42% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $1,358,616 808,700 0.38% Shares
Bank of New York Mellon Corp $1,289,512 767,567 0.36% Shares
DIMENSIONAL FUND ADVISORS LP $1,277,135 759,783 0.35% Shares
Casdin Capital, LLC $1,215,929 723,767 0.34% Shares
TUDOR INVESTMENT CORP ET AL $1,150,308 684,707 0.32% Shares
XTX Topco Ltd $1,073,322 638,882 0.30% Shares
Numerai GP LLC $1,044,068 621,469 0.29% Shares
CARRET ASSET MANAGEMENT, LLC $1,008,235 600,140 0.28% Shares
Man Group plc $1,003,521 597,334 0.28% Shares
Russell Investments Group, Ltd. $1,002,694 596,843 0.28% Shares
Balyasny Asset Management L.P. $948,090 564,339 0.26% Shares
PEAK6 LLC $933,327 555,552 0.26% Shares
Vestmark Advisory Solutions, Inc. $803,384 478,205 0.22% Shares
MORGAN STANLEY $802,664 477,776 0.22% Shares
ArrowMark Colorado Holdings LLC $786,882 468,382 0.22% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $741,954 441,639 0.21% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $673,008 400,600 0.19% Put option

Show all 244 institutional owners →

Activists & 5%+ owners 1 position

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Magnetar Financial LLC, Magnetar Capital Partners LP, Supernova Management LLC, Alec N. Litowitz ×3 filings Aug. 29, 2019 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 30 insiders · 6 officers · 11 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Mark Van Oene President & CEO Aug. 17, 2026 S 2,705,853 0 4 $-335,122
Susan K Barnes EVP, CFO and PAO Feb. 19, 2020 S 874,812 0 0 $0
James Michael Phillips SVP, Research & Development March 24, 2020 S 249,220 0 0 $0
Kevin P Corcoran SVP, Market Development Nov. 24, 2017 M 158,174 0 0 $0
Michael Glynn Chief Commercial Officer Feb. 15, 2012 A · 0 0 $0
Stephen W Turner VP & Chief Technology Officer July 11, 2011 J 1,093,063 0 0 $0
Christopher Gibson Director June 3, 2026 A 111,386 0 0 $0
Hannah Valantine Director June 3, 2026 A 22,821 0 0 $0
William W. Ericson Director June 3, 2026 A 41,616 0 0 $0
Christopher M Smith Director June 3, 2026 A 54,099 0 0 $0
Marshall Mohr Director June 3, 2026 A 132,821 0 0 $0
Randall S Livingston Director June 3, 2026 A 22,821 0 0 $0
Kathy Ordonez Director June 3, 2026 A 403,037 0 0 $0
John F Milligan Director June 3, 2026 A 132,821 0 0 $0
David B. Singer Director June 13, 2012 A · 0 0 $0
Susan E Siegel Director June 13, 2012 A 65,000 0 0 $0
Hugh C Martin Director Feb. 3, 2012 M 342,458 0 0 $0
James R Gibson II · April 1, 2026 S 1,245,663 0 1 $-120,813
Michele Farmer · March 3, 2026 S 305,948 0 3 $-84,510
Christian O Henry · March 3, 2026 S 3,581,813 0 3 $-772,728
Lucy Shapiro · June 4, 2025 A 22,821 0 0 $0
Susan G. Kim · Sept. 30, 2024 S 695,654 0 0 $0
Jeff Eidel · Aug. 19, 2024 S 869,730 0 0 $0
David W Meline · June 18, 2024 A 57,116 0 0 $0
David Botstein · May 24, 2023 A 0 0 0 $0
Peter Fromen · March 2, 2022 A 190,280 0 0 $0
Michael Hunkapiller · Feb. 26, 2021 M 848,405 0 0 $0
Eric Schaefer · Feb. 22, 2021 S 88,474 0 0 $0
BYERS BROOK H · May 17, 2016 A 110,504 0 0 $0
Brian B Dow · March 2, 2015 P 18,119 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 21 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.97% 88,548 SH Oct. 2, 2026 Daily
ARKG · ARK ETF Trust 0.96% 10,630,263 NS July 31, 2026 N-PORT
IDNA · iShares Trust 0.35% 711,655 SH Sept. 11, 2026 Daily
ARKK · ARK ETF Trust 0.32% 12,810,378 NS July 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.09% 981,246 SH Oct. 2, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.05% 21,993 SH Oct. 2, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.03% 280,941 SH Aug. 19, 2026 Daily
IBB · iShares Trust 0.03% 2,192,352 SH Sept. 11, 2026 Daily
IWO · iShares Trust 0.02% 2,473,318 SH Sept. 11, 2026 Daily
RSSL · Global X Funds 0.01% 134,834 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.01% 7,217,251 SH Sept. 11, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.01% 3,579,782 SH Aug. 19, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 1,624,029 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 727,094 SH Aug. 19, 2026 Daily
ITOT · iShares Trust 0.00% 431,328 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 69,680 SH Sept. 9, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 9,535,565 SH Aug. 19, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 17,047 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 22,805 SH Aug. 19, 2026 Daily
DFAC · Dimensional ETF Trust 0.00% 8,144 NS July 31, 2026 N-PORT
IWN · iShares Trust · 207,024 SH Sept. 11, 2026 Daily

PACB Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 14 analysts BUY
Median target $2.00 -21.3%
4 28.6% Strong Buy
5 35.7% Buy
4 28.6% Hold
1 7.1% Sell
0 0.0% Strong Sell

12-Month Price Target

7 analysts · 2026-10-02

Mean target $2.16 -15.1%

Now Current price $2.54
Low$1.25 Mean$2.16 High$3.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PACB $565M -1.0 3.9% -341.5% -1634.9% 28.6%
BLFS · -241.8 28.9% · · ·
PSNL $816M -8.7 -17.7% -116.7% -36.0% ·
AZTA $1.32B -23.5 3.5% -9.4% -3.3% 45.5%
CYRX $479M 6.9 12.4% 44.4% 15.3% 47.1%
DNA $484M -1.5 -25.1% -183.8% -55.8% ·
CTKB $649M 505.0 0.52% -33.0% -18.5% 51.8%
MLAB $489M 73.1 3.4% 2.7% 3.7% 63.5%
OABI · · · · · ·
TKNO $204M -11.9 7.3% -42.6% -23.8% 33.2%
QSI · · · · · ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 6, 2026