PACB Pacific Biosciences of California, Inc. - Common Stock

NASDAQ · Life Sciences Tools & Services · View on SEC EDGAR ↗
$1.23
Price · Aug 19, 2026
Fundamentals as of Aug 6, 2026

About Pacific Biosciences of California, Inc. - Common Stock Company overview from Wikipedia

Pacific Biosciences of California, Inc. is an American biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation. PacBio has two principal sequencing platforms: single-molecule real-time sequencing (SMRT), based on the properties of zero-mode waveguides and sequencing by binding (SBB) chemistry, which uses native nucleotides and scarless incorporation for DNA binding and extension.

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Pacific Biosciences of California, Inc. (a.k.a. PacBio) is an American biotechnology company founded in 2004 that develops and manufactures systems for gene sequencing and some novel real time biological observation. PacBio has two principal sequencing platforms: single-molecule real-time sequencing (SMRT), based on the properties of zero-mode waveguides and sequencing by binding (SBB) chemistry, which uses native nucleotides and scarless incorporation for DNA binding and extension.

History

The company was founded based on research done at Cornell University that combined semiconductor processing and photonics with biotechnology research. Three graduate students in the lab of Professors Watt W. Webb — Jonas Korlach — and Harold Craighead — Steve Turner and Mathieu Foquet — became the first employees.

It began under the name Nanofluidics, Inc. The company raised nearly US$400,000,000 in six rounds of primarily venture capital financing, making it one of the most capitalized startups in 2010 leading up to their public offering in October of that year. Key investors included Mohr Davidow Ventures, Kleiner, Perkins, Caufield & Byers, Alloy Ventures, and Wellcome Trust.

The company's first commercial product, the PacBio RS, was sold to a limited set of customers in 2010 and was commercially released in early 2011. A subsequent version of the sequencer called the PacBio RS II was released in April 2013.

Leadership

In 2004, Kleiner Perkins entrepreneur-in-residence Hugh Martin became CEO. On 6 January 2012 board member Michael Hunkapiller, PhD assumed the role of CEO. Hunkapiller retired in September 2020, and was replaced by chairman of the board Christian Henry. Henry was a former executive VP and chief commercial officer of Illumina before joining the board at PacBio in July 2018.

Illumina: attempted acquisition

On 1 November 2018, Illumina, Inc. agreed to purchase PacBio for US$1.2 billion in cash. The deal was expected to close in the fourth quarter of 2019. In December 2019, the Federal Trade Commission sued to block the acquisition. The deal was abandoned with an announcement on 2 January 2020. Illumina further agreed to pay Pacific Biosciences a $98 million US termination fee plus previously agreed upon deal extension payments of $22 million US in February and $6 million US in March 2020.

Sequencing technology

Sequencing instruments

The company's first scientific instrument, called the PacBio RS, was released to a limited set of customers in late 2010., with full commercial release in early 2011. Sequencing provider GATC Biotech was selected by Pacific Biosciences as its first European service provider in late 2010. A new version of the sequencer was released in April 2013 it produced longer sequence reads and higher throughput than the original RS instrument. The RS instrument will officially be supported until the end of 2021. In September 2015, the company released a new sequencing instrument, the Sequel System, with increased sequencing capacity at a smaller size and lower price compared to the PacBio RS II. Subsequently, in October 2022, PacBio launched a new sequencing system, which can sequence 1,300 human genomes per year as compared to 86 per year of the previous PacBio sequencing machines.

Reagents and SMRT Cells

To use either instrument, customers must also purchase reagent packs for DNA preparation and sequencing and small consumables called "SMRT Cells." Cells for early forms of the sequencer are slightly less than one-centimeter square and contains tens of thousands of zero-mode waveguides, whereas newer systems have a higher density of cells and contain 25 million zero-mode waveguides (ZMWGs), allowing for faster DNA sequencing.

Software and applications

Their secondary analysis bioinformatics product for the RS, called “SMRT Analysis”, was open source. For the Sequel system the secondary analysis software was reorganized as the "SMRT Link" application. In 2013, the company released new bioinformatics tools for automated genome assembly (HGAP) and finishing (Quiver).

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

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PACB Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$1.23
Market Cap
$382M
P/E (TTM)
-0.7
EPS (TTM)
$-1.82
Revenue (TTM)
$160M
Div Yield
ROE
-1634.9%
Debt/Equity
52W Range
$1 – $3

PACB Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $160M
10-point trend, +76.4%
2016-12-31 2025-12-31
EPS $-1.82
8-point trend, -139.5%
2018-12-31 2025-12-31
Free Cash Flow $-114M
10-point trend, -49.6%
2016-12-31 2025-12-31
Margins -341.5%
10-point trend, -41.2%
2016-12-31 2025-12-31

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
PACB
Peer Median
P/E (TTM)
5-point trend, +95.5%
-0.7
17.5
P/S (TTM)
5-point trend, -89.8%
2.4
3.3
P/B
5-point trend, +1746.8%
71.5
2.1
Price / FCF
5-point trend, +87.2%
-3.4

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
PACB
Peer Median
Gross Margin
5-point trend, -36.6%
28.6%
42.5%
Operating Margin
5-point trend, -114.7%
-346.1%
Net Profit Margin
5-point trend, -145.9%
-341.5%
-56.5%
ROA
5-point trend, -257.0%
-53.4%
-17.2%
ROE
5-point trend, -7261.2%
-1634.9%
-41.3%
ROIC
4-point trend, -59102.9%
-10360.5%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
PACB
Peer Median
Current Ratio
5-point trend, -66.5%
5.1
4.9
Quick Ratio
5-point trend, -71.0%
4.3

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
PACB
Peer Median
Revenue YoY
5-point trend, +22.6%
3.9%
Revenue CAGR 3Y
5-point trend, +22.6%
7.6%
Revenue CAGR 5Y
5-point trend, +22.6%
15.2%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
PACB
Peer Median
EPS (Diluted)
5-point trend, -104.5%
$-1.82

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
PACB
Peer Median

PACB Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 14 analysts
  • Strong Buy 4 28.6%
  • Buy 5 35.7%
  • Hold 4 28.6%
  • Sell 1 7.1%
  • Strong Sell 0 0.0%

12-Month Price Target

6 analysts · 2026-08-14
Median target $2.50 +103.0%
Mean target $2.29 +86.1%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.19%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.14 $-0.13 -0.01%
March 31, 2026 $-0.12 $-0.14 0.02%
Dec. 31, 2025 $-0.12 $-0.15 0.03%
Sept. 30, 2025 $-0.13 $-0.15 0.03%
June 30, 2025 $-0.14 $-0.17 0.03%
March 31, 2025 $-1.44 $-0.19 -1.2%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PACB $565M -1.0 3.9% -341.5% -1634.9% 28.6%
CTKB $649M 505.0 0.52% -33.0% -18.5% 51.8%
MLAB $489M 73.1 3.4% 2.7% 3.7% 63.5%
OABI
DNA $484M -1.5 -25.1% -183.8% -55.8%
TKNO $204M -11.9 7.3% -42.6% -23.8% 33.2%
LAB $495M -6.4 -6.2% -87.8% -17.6% 49.9%
LFCR $249M -5.3 0.47% -30.0% -461.3% 31.3%
CDXS $147M -3.3 18.6% -62.5% -82.8%
QSI
MXCT $166M -3.7 -14.5% -135.1% -24.6% 81.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 17
Annual Income Statement data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +164.1% $160M $154M $201M $128M $131M $79M $91M $79M $93M $91M $93M $61M
Cost of Revenue 12-point trend, +207.1% $114M $117M $148M $79M $72M $46M $56M $54M $59M $47M $39M $37M
Gross Profit 12-point trend, +95.6% $46M $37M $53M $49M $59M $33M $35M $25M $35M $44M $53M $23M
R&D Expense 12-point trend, +101.8% $97M $135M $187M $193M $113M $64M $60M $63M $65M $68M $60M $48M
SG&A Expense 12-point trend, +272.1% $141M $175M $170M $161M $124M $73M $75M $63M $59M $48M $45M $38M
Operating Expenses 12-point trend, +595.2% $600M $512M $387M $356M $269M $137M $135M $126M $124M $115M $83M $86M
Operating Income 12-point trend, -781.2% $-554M $-474M $-334M $-307M $-210M $-104M $-101M $-101M $-90M $-71M $-29M $-63M
Interest Expense 10-point trend, +407.2% · · $14M $15M $13M $267.0K $3M $2M $3M $3M $3M $3M
Other Non-op 12-point trend, +3187.2% $15M $24M $33M $8M $93.0K $2M $1M $848.0K $516.0K $103.0K $364.0K $-478.0K
Pretax Income 7-point trend, -549.0% $-546M $-310M $-318M $-314M $-275M $29M $-84M · · · · ·
Income Tax 5-point trend, +100.3% $318.0K $316.0K $-11M $0 $-94M · · · · · · ·
Net Income 12-point trend, -725.8% $-546M $-310M $-307M $-314M $-181M $29M $-84M $-103M $-92M $-74M $-32M $-66M
EPS (Basic) 8-point trend, -139.5% $-1.82 $-1.13 $-1.21 $-1.40 $-0.89 $0.18 $-0.55 $-0.76 · · · ·
EPS (Diluted) 8-point trend, -139.5% $-1.82 $-1.59 $-1.21 $-1.40 $-0.89 $0.17 $-0.55 $-0.76 · · · ·
Shares (Basic) 8-point trend, +122.0% 299,959,000 274,488,000 253,629,000 224,550,000 204,136,000 165,187,000 152,527,000 135,094,000 · · · ·
Shares (Diluted) 8-point trend, +122.0% 299,959,000 288,366,000 253,629,000 224,550,000 204,136,000 174,970,000 152,527,000 135,094,000 · · · ·
EBITDA 12-point trend, -844.6% $-554M $-474M $-334M $-307M $-210M $-104M $-101M $-94M $-81M $-67M $-25M $-59M
Balance Sheet 30
Annual Balance Sheet data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +74.8% $64M $55M $180M $325M $461M $82M $30M $19M $17M $17M $34M $36M
Short-term Investments 12-point trend, +232.5% $216M $335M $452M $447M $584M $237M $19M $84M $46M $55M $49M $65M
Receivables 12-point trend, +940.8% $35M $28M $37M $19M $24M $17M $15M $9M $13M $11M $5M $3M
Inventory 12-point trend, +334.8% $49M $59M $57M $50M $25M $14M $13M $18M $23M $16M $11M $11M
Prepaid Expense 12-point trend, +545.9% $11M $19M $17M $10M $7M $5M $3M $3M $2M $10M $12M $2M
Other Current Assets 4-point trend, +770.1% · · · · · · · · $931.0K $476.0K $741.0K $107.0K
Current Assets 12-point trend, +218.5% $375M $496M $742M $852M $1.10B $356M $81M $132M $102M $109M $111M $118M
PP&E (Net) 12-point trend, +265.8% $24M $31M $36M $42M $33M $25M $30M $34M $38M $15M $9M $7M
PP&E (Gross) 12-point trend, +214.7% $117M $112M $111M $107M $89M $75M $74M $71M $70M $52M $42M $37M
Accum. Depreciation 12-point trend, +203.6% $92M $82M $75M $65M $56M $50M $44M $37M $32M $37M $34M $30M
Goodwill 5-point trend, -22.5% $318M $318M $462M $410M $410M · · · · · · ·
Intangibles 5-point trend, -96.3% $15M $390M $457M $410M $411M · · · · · · ·
Other Non-current Assets 12-point trend, +30151.7% $9M $9M $13M $11M $1M $43.0K $42.0K $43.0K $45.0K $10M $8M $29.0K
Total Assets 12-point trend, +530.3% $784M $1.26B $1.75B $1.77B $2.01B $414M $148M $170M $144M $138M $131M $124M
Accounts Payable 12-point trend, +270.4% $21M $17M $15M $12M $11M $4M $8M $7M $9M $8M $5M $6M
Accrued Liabilities 12-point trend, +194.1% $34M $23M $46M $33M $36M $17M $13M $13M $13M $17M $16M $11M
Short-term Debt 5-point trend, -100.0% · $0 $490.0K $2M $2M · $16M · · · · ·
Current Liabilities 12-point trend, +131.3% $73M $66M $95M $263M $72M $39M $49M $27M $29M $34M $38M $31M
Capital Leases 8-point trend, +2531.0% $57M $15M $32M $41M $50M $38M $42M · · · · $2M
Other Non-current Liabilities 9-point trend, -100.0% $0 $546.0K $751.0K $1M $3M $752.0K · · · $2M $1M $2M
Total Liabilities 12-point trend, +1021.4% $779M $754M $1.04B $1.20B $1.22B $78M $93M $56M $58M $53M $58M $69M
Long-term Debt 7-point trend, +6248.6% · · · $897M $896M · $16M $15M $14M $16M · $14M
Total Debt 5-point trend, -100.0% · $0 $490.0K $2M $2M · $16M · · · · ·
Common Stock 12-point trend, +308.1% $302.0K $294.0K $268.0K $227.0K $221.0K $192.0K $153.0K $150.0K $116.0K $93.0K $80.0K $74.0K
Paid-in Capital 12-point trend, +266.7% $2.70B $2.65B $2.54B $2.10B $2.01B $1.37B $1.12B $1.10B $966M $872M $787M $736M
Retained Earnings 12-point trend, -295.5% $-2.70B $-2.15B $-1.84B $-1.53B $-1.22B $-1.04B $-1.07B $-982M $-880M $-788M $-713M $-681M
AOCI 12-point trend, +4977.8% $457.0K $422.0K $219.0K $-5M $-1M $85.0K $5.0K $-36.0K $-32.0K $5.0K $-7.0K $9.0K
Stockholders' Equity 12-point trend, -90.3% $5M $507M $701M $563M $791M $335M $55M $114M $86M $85M $74M $55M
Liabilities + Equity 12-point trend, +530.3% $784M $1.26B $1.75B $1.77B $2.01B $414M $148M $170M $144M $138M $131M $124M
Shares Outstanding 12-point trend, +308.5% 301,956,000 294,418,000 267,744,000 226,505,000 220,978,000 192,294,000 153,119,000 150,244,000 116,277,000 92,677,000 79,983,000 73,927,000
Cash Flow 16
Annual Cash Flow data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
D&A 5-point trend, +70.9% · · · · · · · $7M $8M $4M $4M $4M
Stock-based Comp 12-point trend, +319.1% $42M $71M $72M $79M $73M $18M $16M $23M $20M $20M $14M $10M
Deferred Tax 5-point trend, +99.4% $-546.0K $-205.0K $-11M $0 $-94M · · · · · · ·
Amort. of Intangibles 7-point trend, +369448000.00 $369M $27M $8M $913.0K $0 $0 $0 · · · · ·
Restructuring · $13M · · · · · · · · · ·
Other Non-cash 5-point trend, +991.7% · · · · · · · $6M $-4M $-17M $-34M $528.0K
Operating Cash Flow 12-point trend, -116.1% $-111M $-206M $-259M $-263M $-111M $20M $-78M $-66M $-68M $-68M $-48M $-51M
CapEx 12-point trend, +68.7% $3M $6M $9M $17M $6M $1M $3M $2M $10M $8M $3M $2M
Investing Cash Flow 10-point trend, +876.7% $115M $124M $5M $116M $-679M $-219M $62M $-38M $-2M $-15M · ·
Stock Issued 12-point trend, -100.0% $0 $0 $189M $0 $32M $46M $9M $10M $9M $8M $7M $4M
Net Stock Activity 12-point trend, -100.0% $0 $0 $15M $11M $32M $46M $9M $10M $9M $8M $7M $4M
Financing Cash Flow 10-point trend, -94.8% $3M $-43M $109M $10M $1.17B $252M $27M $107M $69M $66M · ·
Net Change in Cash 9-point trend, -24.0% $8M $-125M $-146M $-138M $380M · · · $-258.0K $-17M $-3M $10M
Taxes Paid 3-point trend, +243.6% $481.0K $256.0K $140.0K · · · · · · · · ·
Free Cash Flow 12-point trend, -114.6% $-114M $-212M $-268M $-280M $-117M $18M $-81M $-68M $-78M $-76M $-51M $-53M
Levered FCF 2-point trend, -124.8% · · $-282M · $-125M · · · · · · ·
Profitability 8
Annual Profitability data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
Gross Margin 12-point trend, -25.9% 28.6% 24.2% 26.3% 38.2% 45.1% 41.3% 38.0% 31.9% 37.1% 48.7% 57.6% 38.6%
Operating Margin 12-point trend, -233.7% -346.1% -308.0% -166.8% -239.4% -161.2% -132.3% -110.6% -128.4% -96.1% -78.5% -31.4% -103.7%
Net Margin 12-point trend, -212.7% -341.5% -201.2% -153.0% -244.9% -138.8% 37.3% -92.6% -130.4% -98.6% -82.0% -34.2% -109.2%
Pretax Margin 5-point trend, -62.0% -341.3% -201.0% -158.7% -244.9% -210.6% · · · · · · ·
EBITDA Margin 12-point trend, -257.7% -346.1% -308.0% -166.8% -239.4% -161.2% -132.3% -110.6% -119.3% -87.0% -74.3% -27.4% -96.8%
ROA 12-point trend, -5.3% -53.4% -20.6% -17.5% -16.7% -15.0% 10.5% -52.9% -65.2% -65.4% -55.3% -24.8% -50.7%
ROE 12-point trend, -1433.7% -1634.9% -64.6% -41.9% -52.8% -22.2% 12.7% -158.8% -83.4% -108.0% -94.0% -49.3% -106.6%
ROIC 4-point trend, -59102.9% -10360.5% -93.7% -46.0% · -17.5% · · · · · · ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, +37.7% 5.1 7.5 7.8 3.2 15.4 9.2 1.6 4.9 3.5 3.2 2.9 3.7
Quick Ratio 12-point trend, +30.0% 4.3 6.3 7.0 3.0 14.9 8.7 1.3 4.1 2.7 2.5 2.3 3.3
Debt / Equity 5-point trend, -100.0% · 0.0 0.0 0.0 0.0 · 0.3 · · · · ·
Interest Coverage 10-point trend, -4.9% · · -23.3 -20.9 -16.8 -391.0 -38.5 -41.7 -30.7 -22.0 -10.0 -22.2
Efficiency 3
Annual Efficiency data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 12-point trend, -66.3% 0.2 0.1 0.1 0.1 0.1 0.3 0.6 0.5 0.7 0.7 0.7 0.5
Inventory Turnover 12-point trend, -39.2% 2.1 2.0 2.8 2.1 3.7 3.4 3.6 2.6 3.0 3.5 3.5 3.5
Receivables Turnover 12-point trend, -74.2% 5.1 4.8 7.2 6.0 6.4 4.9 7.6 7.1 7.5 10.9 21.4 19.7
Per Share 6
Annual Per Share data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, -97.6% $0.02 $1.72 $2.62 $2.49 $3.58 $1.74 $0.36 $0.76 $0.74 $0.91 $0.92 $0.74
Revenue / Share 6-point trend, +18.3% $0.53 $0.53 $0.79 $0.57 $0.64 $0.45 · · · · · ·
Cash Flow / Share 6-point trend, -432.5% $-0.37 $-0.71 $-1.02 $-1.17 $-0.54 $0.11 · · · · · ·
Cash / Share 12-point trend, -57.2% $0.21 $0.19 $0.67 $1.44 $2.08 $0.42 $0.19 $0.13 $0.14 $0.18 $0.42 $0.49
Dividend / Share Flat — no change across 12 periods $0 $0 $0 $0 $0 $0 $0 $0 $0 $0 $0 $0
EPS (TTM) 8-point trend, -139.5% $-1.82 $-1.59 $-1.21 $-1.40 $-0.89 $0.17 $-0.55 $-0.76 · · · ·
Growth Rates 3
Annual Growth Rates data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -94.1% 3.9% -23.2% 56.3% -1.7% 65.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, -79.1% 7.6% 5.7% 36.5% · · · · · · · · ·
Revenue CAGR 5Y 15.2% · · · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for PACB
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +164.1% $160M $154M $201M $128M $131M $79M $91M $79M $93M $91M $93M $61M
Net Income TTM 12-point trend, -725.8% $-546M $-310M $-307M $-314M $-181M $29M $-84M $-103M $-92M $-74M $-32M $-66M
Market Cap 12-point trend, -2.6% $565M $539M $2.63B $1.85B $4.52B $4.99B $787M $1.11B $307M $352M $1.05B $580M
Enterprise Value 5-point trend, -80.3% · $149M $2.00B $1.08B $3.48B · $754M · · · · ·
P/E 8-point trend, +89.4% -1.0 -1.2 -8.1 -5.8 -23.0 152.6 -9.3 -9.7 · · · ·
P/S 12-point trend, -63.1% 3.5 3.5 13.1 14.4 34.6 63.2 8.7 14.1 3.3 3.9 11.3 9.6
P/B 12-point trend, +900.8% 105.6 1.1 3.7 3.3 5.7 14.9 14.3 9.7 3.6 4.2 14.3 10.5
P / Tangible Book · · · · · 14.9 · · · · · ·
P / Cash Flow 12-point trend, +54.9% -5.1 -2.6 -10.1 -7.0 -40.7 255.8 -10.0 -16.7 -4.5 -5.2 -21.9 -11.3
P / FCF 12-point trend, +54.6% -5.0 -2.5 -9.8 -6.6 -38.6 270.2 -9.7 -16.3 -3.9 -4.6 -20.6 -10.9
EV / EBITDA 5-point trend, +95.8% · -0.3 -6.0 -3.5 -16.5 · -7.5 · · · · ·
EV / FCF 5-point trend, +92.5% · -0.7 -7.4 -3.9 -29.7 · -9.3 · · · · ·
EV / Revenue 5-point trend, -88.3% · 1.0 10.0 8.4 26.7 · 8.3 · · · · ·
Earnings Yield 8-point trend, -847.7% -97.3% -86.9% -12.3% -17.1% -4.3% 0.66% -10.7% -10.3% · · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $160M$154M$201M$128M$131M
Gross Margin % 28.6%24.2%26.3%38.2%45.1%
Operating Margin % -346.1%-308.0%-166.8%-239.4%-161.2%
Net Income $-546M$-310M$-307M$-314M$-181M
Diluted EPS $-1.82$-1.59$-1.21$-1.40$-0.89
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.00.00.00.0
Current Ratio 5.17.57.83.215.4
Quick Ratio 4.36.37.03.014.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-114M$-212M$-268M$-280M$-117M

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Institutional owners (13F) 247 filers · $274.5M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
29 (-21 vs prior Q) 28 (-2 vs prior Q) 65 (+10 vs prior Q) 79 (+2 vs prior Q) +13.0M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
ARK Investment Management LLC $50,032,778 29,781,416 18.23% Shares
SOFTBANK GROUP CORP. $34,358,638 20,451,570 12.52% Shares
VANGUARD GROUP INC $28,083,542 15,017,937 10.23% Shares
VANGUARD CAPITAL MANAGEMENT LLC $22,508,529 13,397,934 8.20% Shares
GEODE CAPITAL MANAGEMENT, LLC $10,951,905 6,516,920 3.99% Shares
Sumitomo Mitsui Trust Group, Inc. $10,096,321 6,009,715 3.68% Shares
Amova Asset Management Americas, Inc. $10,036,224 6,009,715 3.66% Shares
STATE STREET CORP $10,014,774 5,961,175 3.65% Shares
Point72 Asset Management, L.P. $8,042,664 4,787,300 2.93% Shares
TWO SIGMA INVESTMENTS, LP $7,127,566 4,242,599 2.60% Shares
MILLENNIUM MANAGEMENT LLC $6,656,903 3,962,442 2.43% Shares
Point72 (DIFC) Ltd $5,465,775 4,270,137 1.99% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $4,488,819 2,671,916 1.64% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4,455,861 2,652,298 1.62% Shares
D. E. Shaw & Co., Inc. $3,959,804 2,357,026 1.44% Shares
VANGUARD FIDUCIARY TRUST CO $3,675,213 2,187,627 1.34% Shares
Longaeva Partners L.P. $3,558,628 2,118,231 1.30% Shares
GOLDMAN SACHS GROUP INC $3,262,914 1,942,211 1.19% Shares
IQ EQ FUND MANAGEMENT (IRELAND) Ltd $2,846,837 1,694,546 1.04% Shares
Birchview Capital, LP $2,268,000 1,350,000 0.83% Shares
BlackRock, Inc. $2,210,561 1,315,810 0.81% Shares
BANK OF AMERICA CORP /DE/ $1,812,811 1,079,054 0.66% Shares
RENAISSANCE TECHNOLOGIES LLC $1,623,216 966,200 0.59% Shares
BOURNE LENT ASSET MANAGEMENT INC $1,584,332 943,055 0.58% Shares
TWO SIGMA ADVISERS, LP $1,547,425 827,500 0.56% Shares
HHLR ADVISORS, LTD. $1,543,739 918,892 0.56% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $1,358,616 808,700 0.49% Shares
Casdin Capital, LLC $1,215,929 723,767 0.44% Shares
TUDOR INVESTMENT CORP ET AL $1,150,308 684,707 0.42% Shares
DIMENSIONAL FUND ADVISORS LP $1,095,649 652,172 0.40% Shares
XTX Topco Ltd $1,073,322 638,882 0.39% Shares
Numerai GP LLC $1,044,068 621,469 0.38% Shares
CARRET ASSET MANAGEMENT, LLC $1,008,235 600,140 0.37% Shares
Man Group plc $1,003,521 597,334 0.37% Shares
Balyasny Asset Management L.P. $948,090 564,339 0.35% Shares
PEAK6 LLC $933,327 555,552 0.34% Shares
Vestmark Advisory Solutions, Inc. $803,384 478,205 0.29% Shares
ArrowMark Colorado Holdings LLC $786,882 468,382 0.29% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $741,954 441,639 0.27% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $673,008 400,600 0.25% Put option
RHUMBLINE ADVISERS $599,738 356,996 0.22% Shares
CAXTON ASSOCIATES LP $577,087 315,348 0.21% Shares
Mirador Capital Partners LP $575,370 342,482 0.21% Shares
LPL Financial LLC $567,003 337,502 0.21% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $566,071 336,947 0.21% Shares
Connor, Clark & Lunn Investment Management Ltd. $529,407 315,123 0.19% Shares
ALLIANCEBERNSTEIN L.P. $510,919 387,060 0.19% Shares
Qube Research & Technologies Ltd $500,558 297,951 0.18% Shares
Nuveen Asset Management, LLC $494,437 270,184 0.18% Shares
GROUP ONE TRADING LLC $488,645 290,860 0.18% Shares
WATER ISLAND CAPITAL LLC $459,759 273,666 0.17% Shares
HSBC HOLDINGS PLC $457,555 277,306 0.17% Shares
BARCLAYS PLC $447,482 266,359 0.16% Shares
WELLS FARGO & COMPANY/MN $430,196 256,069 0.16% Shares
Bank of New York Mellon Corp $426,179 253,678 0.16% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $406,056 241,700 0.15% Call option
Quadrature Capital Ltd $311,899 185,654 0.11% Shares
Green Alpha Advisors, LLC $300,140 178,655 0.11% Shares
MARSHALL WACE, LLP $274,919 163,642 0.10% Shares
UBS Group AG $271,868 161,826 0.10% Shares
MetLife Investment Management, LLC $264,093 157,198 0.10% Shares
RAYMOND JAMES FINANCIAL INC $260,524 155,074 0.09% Shares
AdvisorNet Financial, Inc $255,565 152,122 0.09% Shares
Main Street Research LLC $255,528 152,100 0.09% Shares
JANE STREET GROUP, LLC $255,192 151,900 0.09% Call option
Voleon Capital Management LP $226,521 134,834 0.08% Shares
ENVESTNET ASSET MANAGEMENT INC $223,315 132,926 0.08% Shares
IEQ CAPITAL, LLC $207,954 123,782 0.08% Shares
CITIGROUP INC $206,867 123,135 0.08% Shares
Vanguard Global Advisers, LLC $204,592 121,781 0.07% Shares
Koa Wealth Management, LLC $201,600 120,000 0.07% Shares
Invesco Ltd. $188,456 112,176 0.07% Shares
CITADEL ADVISORS LLC $186,144 110,800 0.07% Call option
BENJAMIN EDWARDS INC $179,922 107,153 0.07% Shares
KAVAR CAPITAL PARTNERS GROUP, LLC $173,576 103,319 0.06% Shares
Bridgewater Associates, LP $172,638 102,761 0.06% Shares
GABELLI FUNDS LLC $168,000 100,000 0.06% Shares
CITADEL ADVISORS LLC $152,964 91,050 0.06% Shares
NEW YORK STATE COMMON RETIREMENT FUND $142,506 84,825 0.05% Shares
Police & Firemen's Retirement System of New Jersey $134,324 79,955 0.05% Shares
NJ State Employees Deferred Compensation Plan $128,000 100,000 0.05% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $126,573 75,341 0.05% Shares
HUB Investment Partners, LLC $126,000 75,000 0.05% Shares
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $120,861 71,941 0.04% Shares
HARTLINE INVESTMENT CORP/ $115,920 69,000 0.04% Shares
Cerity Partners LLC $115,811 68,935 0.04% Shares
STIFEL FINANCIAL CORP $114,659 68,249 0.04% Shares
INTECH INVESTMENT MANAGEMENT LLC $113,249 67,410 0.04% Shares
SIMPLEX TRADING, LLC $110,307 65,659 0.04% Shares
CITADEL ADVISORS LLC $109,536 65,200 0.04% Put option
Nuveen, LLC $99,117 58,998 0.04% Shares
VOYA INVESTMENT MANAGEMENT LLC $96,004 57,145 0.03% Shares
CAPTRUST FINANCIAL ADVISORS $94,854 56,461 0.03% Shares
Cetera Investment Advisers $91,834 54,663 0.03% Shares
State of Wyoming $91,169 54,267 0.03% Shares
MERCER GLOBAL ADVISORS INC /ADV $86,972 51,769 0.03% Shares
Abacus Planning Group, Inc. $86,080 51,238 0.03% Shares
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $85,770 54,981 0.03% Shares
Evolution Wealth Advisors, LLC $84,000 50,000 0.03% Shares
China Universal Asset Management Co., Ltd. $83,046 49,432 0.03% Shares

Company insiders 30 insiders · 6 officers · 11 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Mark Van Oene President & CEO Aug. 17, 2026 S 2,705,853 0 5 $-370,277
Susan K Barnes EVP, CFO and PAO Feb. 19, 2020 S 874,812 0 0 $0
James Michael Phillips SVP, Research & Development March 24, 2020 S 249,220 0 0 $0
Kevin P Corcoran SVP, Market Development Nov. 24, 2017 M 158,174 0 0 $0
Michael Glynn Chief Commercial Officer Feb. 15, 2012 A 0 0 $0
Stephen W Turner VP & Chief Technology Officer July 11, 2011 J 1,093,063 0 0 $0
Christopher Gibson Director June 3, 2026 A 53,913 0 0 $0
Hannah Valantine Director June 3, 2026 A 22,821 0 0 $0
William W. Ericson Director June 3, 2026 A 41,616 0 0 $0
Christopher M Smith Director June 3, 2026 A 54,099 0 0 $0
Marshall Mohr Director June 3, 2026 A 132,821 0 0 $0
Randall S Livingston Director June 3, 2026 A 22,821 0 0 $0
Kathy Ordonez Director June 3, 2026 A 403,037 0 0 $0
John F Milligan Director June 3, 2026 A 132,821 0 0 $0
David B. Singer Director June 13, 2012 A 0 0 $0
Susan E Siegel Director June 13, 2012 A 65,000 0 0 $0
Hugh C Martin Director Feb. 3, 2012 M 342,458 0 0 $0
James R Gibson II April 1, 2026 S 1,245,663 0 1 $-120,813
Michele Farmer March 3, 2026 S 305,948 0 3 $-84,510
Christian O Henry March 3, 2026 S 3,581,813 0 3 $-772,728
Lucy Shapiro June 4, 2025 A 22,821 0 0 $0
Susan G. Kim Sept. 30, 2024 S 695,654 0 0 $0
Jeff Eidel Aug. 19, 2024 S 869,730 0 0 $0
David W Meline June 18, 2024 A 57,116 0 0 $0
David Botstein May 24, 2023 A 0 0 0 $0
Peter Fromen March 2, 2022 A 190,280 0 0 $0
Michael Hunkapiller Feb. 26, 2021 M 848,405 0 0 $0
Eric Schaefer Feb. 22, 2021 S 88,474 0 0 $0
BYERS BROOK H May 17, 2016 A 110,504 0 0 $0
Brian B Dow March 2, 2015 P 18,119 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Magnetar Financial LLC, Magnetar Capital Partners LP, Supernova Management LLC, Alec N. Litowitz ×3 filings Aug. 29, 2019 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 32 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
ARKG · ARK ETF Trust 1.41% 10,964,895 NS April 30, 2026 N-PORT
EVNT · AltShares Trust 0.75% 62,040 NS May 31, 2026 N-PORT
GNOM · Global X Funds 0.40% 151,435 NS May 31, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.39% 75,049 SH Aug. 8, 2026 Daily
IDNA · iShares Trust 0.37% 622,048 SH Aug. 8, 2026 Daily
ARKK · ARK ETF Trust 0.36% 14,733,201 NS April 30, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.04% 1,067,027 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.03% 280,941 SH Aug. 8, 2026 Daily
IBB · iShares Trust 0.03% 2,125,671 SH Aug. 8, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.02% 16,737 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.02% 11,163 NS May 31, 2026 N-PORT
IWO · iShares Trust 0.02% 2,413,297 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.01% 121,533 NS April 30, 2026 N-PORT
IWM · iShares Trust 0.01% 7,202,610 SH Aug. 8, 2026 Daily
ITWO · ProShares Trust 0.01% 12,995 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.01% 3,579,782 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 1,624,029 SH Aug. 8, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 727,094 SH Aug. 8, 2026 Daily
SCHA · SCHWAB STRATEGIC TRUST 0.01% 1,434,895 NS May 31, 2026 N-PORT
UWM · ProShares Trust 0.01% 10,163 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.00% 10,278 NS May 31, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.00% 9,612 NS May 31, 2026 N-PORT
HDG · ProShares Trust 0.00% 258 NS May 31, 2026 N-PORT
IWN · iShares Trust 0.00% 206,229 SH Aug. 8, 2026 Daily
SCHB · SCHWAB STRATEGIC TRUST 0.00% 174,278 NS May 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 431,365 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.00% 48,231 NS April 30, 2026 N-PORT
IWV · iShares Trust 0.00% 68,930 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 9,535,565 SH Aug. 8, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 17,047 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 22,805 SH Aug. 8, 2026 Daily
DFAC · Dimensional ETF Trust 0.00% 8,144 NS April 30, 2026 N-PORT