BCRX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $8.17
Market Cap (MRQ) $2.09B
P/E (TTM) -5.5
EPS (TTM) $-1.49
Revenue (TTM) $941M
ROE (TTM) 87.8%
Debt/Equity (MRQ) -0.9
52W Range $6–$11

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04
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About BioCryst Pharmaceuticals, Inc. - Common Stock Company overview from Wikipedia

05 · wikidata

BioCryst Pharmaceuticals, Inc. is an American pharmaceutical company headquartered in Durham, North Carolina. The company is a commercial stage biotech company that focuses on developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases. BioCryst's antiviral drug peramivir (Rapivab) was approved by the FDA in December 2014 and berotralstat (ORLADEYO) was approved in December 2020.

History

The company was founded in 1986 by Charles E. Bugg and John A. Montgomery. In March 1994, BioCryst became a public company when it completed an initial public offering by listing its shares on the NASDAQ stock exchange. In 2008, the company was named one of the fastest growing companies by Deloitte & Touche in its 2008 list of Technology Fast 500.

In October 2010, BioCryst announced its headquarters would move to Durham, North Carolina, where the company has had an office since 2006. In January 2018, BioCryst signed a definitive merger agreement with Idera Pharmaceuticals, with plans for the combined company to change its name and move to Pennsylvania. However, BioCryst shareholders voted down the merger in July.

Pipeline

BioCryst’s core development programs include:

Berotralstat (BCX7353), an oral inhibitor of plasma kallikrein for prevention and treatment of hereditary angioedema (HAE).

FDA has approved Expanded Access Program for berotralstat for eligible patients in the United States.

Berotralstat has a PDUFA date for FDA approval on December 3, 2020.

On December 3, 2020, the FDA approved berotralstat as the first oral hereditary angioedema prophylaxis.

BCX9930, an oral Factor D inhibitor for the treatment of complement-mediated diseases.

FDA has granted Fast Track designation for BCX9930, for the treatment of paroxysmal nocturnal hemoglobinuria (PNH).

BCX9250, an oral ALK-2 inhibitor for treatment of fibrodysplasia ossificans progressiva (FOP).

Galidesivir (BCX4430) is a broad-spectrum antiviral in advanced development for the treatment of viruses including SARS-CoV-2 (the cause of COVID-19), Ebola, Marburg, Yellow Fever and Zika.

Galidesivir was safe and generally well tolerated in Phase 1 clinical safety and pharmacokinetics trials conducted in 2019 by both intravenous and intramuscular routes of administration in healthy human subjects.

In animal studies, galidesivir has demonstrated survival benefits against a variety of serious pathogens, including Ebola, Marburg, Yellow Fever and Zika viruses.

BioCryst is developing galidesivir in collaboration with U.S. government agencies and other institutions.

In September 2013, NIAID contracted with BioCryst for the development of galidesivir as a treatment for Marburg virus disease and potentially for other filoviruses, including Ebola virus.

In March 2015, BioCryst announced that the Biomedical Advanced Research and Development Authority (BARDA) within the U.S. Department of Health & Human Services’ Office of the Assistant Secretary for Preparedness and Response (ASPR) has awarded BioCryst a contract for the continued development of galidesivir as a potential treatment for diseases caused by RNA pathogens, including filoviruses.

In April 2020, BioCryst began enrollment of a randomized, double-blind, placebo-controlled clinical trial to assess the safety, clinical impact and antiviral effects of galidesivir in patients with COVID-19. This clinical trial is (NCT03891420) is being funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The company later made the decision to cease conducting further trials.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

sectorHealthcare industryBiotechnology employees435 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$875M
2016-12-31 → 2025-12-31
EPS$1.21
2020-12-31 → 2025-12-31
Free Cash Flow$345M
2016-12-31 → 2025-12-31
Net margin-40.9%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend BCRX 5Y avg Peer Median Verdict
P/E (TTM) -5.55Y avg ≈-7.6 ≈-7.6 · ·
P/S (TTM) 2.25Y avg ≈6.7 ≈6.7 29.2 Undervalued
P/B (MRQ) -4.65Y avg ≈-10.2 ≈-10.2 · ·
EV / EBITDA 5.35Y avg ≈-281.5 ≈-281.5 · ·
Price / FCF (TTM) 5.65Y avg ≈-13.6 ≈-13.6 · ·
Price / Cash Flow (TTM) 5.55Y avg ≈-13.9 ≈-13.9 · ·
EV / Revenue (TTM) 2.35Y avg ≈6.3 ≈6.3 · ·
EV / FCF (TTM) 5.75Y avg ≈-14.4 ≈-14.4 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 23.2%
Next Report Nov 02, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 3, 2026 $0.30 $0.12 148.1%
March 31, 2026 $-0.09 $0.05 -281.8%
Dec. 31, 2025 $0.01 $0.04 -74.1%
Sept. 30, 2025 $0.06 $0.04 67.1%
June 30, 2025 $0.04 $0.01 179.7%
March 31, 2025 $0.00 $-0.07 100.0%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 16
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $875M$451M$331M$271M$157M$18M$49M$21M$25M$26M$48M$14M
Cost of Revenue $19M$12M$4M$6M$7M$2M$4M·$1M$2M$1M$1.0K
R&D Expense $166M$175M$217M$253M$209M$123M$107M$85M$67M$61M$73M$52M
SG&A Expense $349M$266M$214M$159M$119M$68M$37M$30M$14M$11M$13M$7M
Operating Expenses $534M$453M$435M$419M$335M$193M$148M$115M$83M$75M$88M$59M
Operating Income $341M$-3M$-104M$-148M$-178M$-175M$-99M$-94M$-57M$-49M$-39M$-46M
Interest Expense ··$108M$99M$59M$15M$12M$9M$9M$6M$5M$5M
Other Non-op $-74M$-84M$-123M$-96M········
Pretax Income $267M$-87M$-226M$-244M$-182M$-183M$-109M·····
Income Tax $4M$2M$310.0K$3M$2M$0$0$0$0$0$0·
Net Income $264M$-89M$-227M$-247M$-184M$-183M$-109M$-101M$-66M$-55M$-43M$-45M
EPS (Basic) $1.26$-0.43$-1.18$-1.33$-1.03$-1.09······
EPS (Diluted) $1.21$-0.43$-1.18$-1.33$-1.03$-1.09······
Shares (Basic) 209,893,000206,696,000192,198,000185,908,000179,117,000167,267,000······
Shares (Diluted) 218,581,000206,696,000192,198,000185,908,000179,117,000167,267,000115,600,000103,185,00084,451,00073,699,00072,901,00066,773,000
EBITDA $342M$-1M$-102M$-147M$-177M$-174M$-99M$-93M·$-48M$-39M$-46M
Balance Sheet 27
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $90M$105M$111M$305M$504M$272M$114M$27M$50M$22M$29M$55M
Short-term Investments $185M$216M··········
Receivables $107M$79M$57M$51M$29M$9M$22M$4M$6M$9M$6M$4M
Inventory $5M$8M$29M$28M$16M$7M$0$2M·$500.0K$2M$683.0K
Prepaid Expense $17M$14M$20M$13M$10M$6M$4M$2M$1M$1M$3M$6M
Current Assets $404M$422M$496M$516M$566M$324M$164M$114M$125M$67M$64M$89M
PP&E (Net) $9M$8M$8M$9M$9M$7M$7M$9M$10M$10M$5M$207.0K
PP&E (Gross) $18M$20M$19M$18M$17M$14M$14M$15M$15M$15M$19M$14M
Accum. Depreciation $9M$12M$11M$10M$8M$7M$7M$6M$5M$5M$14M$14M
Other Non-current Assets $6M$5M$80.0K$7M$6M$4M$4M$978.0K$2M$4M$5M$6M
Total Assets $514M$490M$517M$550M$588M$335M$175M$147M$178M$90M$122M$137M
Accounts Payable $16M$12M$21M$14M$28M$19M$14M$8M$6M$4M$9M$3M
Accrued Liabilities $126M$113M$103M$88M$73M$34M$21M$16M$13M$11M$16M$11M
Short-term Debt ·····$30M$30M$29M$29M$28M$28M$30M
Current Liabilities $196M$160M$150M$106M$104M$106M$92M$69M$75M$54M$62M$57M
Capital Leases $9M$8M$8M$4M$6M$4M······
Other Non-current Liabilities ·······$3M····
Total Liabilities $633M$966M$972M·········
Long-term Debt ····$298M$123M$50M$30M$23M$23M··
Total Debt $0$315M$303M$232M$136M$150M$30M$29M·$28M$30M$30M
Common Stock $2M$2M$2M$2M$2M$2M$2M$1M$984.0K$738.0K$734.0K$720.0K
Paid-in Capital $1.38B$1.29B$1.22B$1.16B$1.10B$1.00B$877M$780M$715M$567M$558M$543M
Retained Earnings $-1.51B$-1.77B$-1.68B$-1.45B$-1.21B$-1.02B$-841M$-732M$-632M$-566M$-511M$-468M
AOCI $38.0K$921.0K$1M$26.0K$177.0K$3.0K$39.0K$-297.0K$-243.0K$-12.0K$-206.0K$-130.0K
Stockholders' Equity $-119M$-476M$-456M$-295M$-107M$-19M$38M$49M$84M$2M$48M$76M
Liabilities + Equity $514M$490M$517M$550M$588M$335M$175M$147M$178M$90M$122M$137M
Shares Outstanding 213,060,000208,543,000205,771,000187,906,000184,350,000176,883,000154,082,000110,063,00098,411,00073,782,00073,355,00071,955,000
Cash Flow 16
Metric Trend 202520242023202220212020201920182017201620152014
D&A $1M$1M$2M$1M$777.0K$748.0K$724.0K$770.0K$704.0K$483.0K$180.0K$177.0K
Stock-based Comp $85M$65M$56M$45M$35M$15M$18M$9M$13M$8M$10M$10M
Deferred Tax $-1M$-354.0K$-682.0K$11.0K$-159.0K·······
Other Non-cash $-2M$-29M$75M$39M$6M$30M$870.0K$-1M·$-7M$20M$-4M
Operating Cash Flow $347M$-52M$-95M$-162M$-142M$-135M$-90M$-93M$-41M$-53M$-13M$-39M
CapEx $2M$1M$2M$1M$2M$514.0K$343.0K$366.0K$328.0K$5M$5M$106.0K
Investing Cash Flow $-14M$53M$-131M$-128M$16M$-7M$78M$5M$-65M$23M$-18M·
Debt Issued $0$0$300M$73M$0·······
Net Debt Issued $-300M$0$300M·········
Stock Issued ··$0$0$50M$93M$58M$53M$134M··$107M
Net Stock Activity ··$0$0$50M$93M$58M$53M···$107M
Financing Cash Flow $-350M$-6M$32M$88M$360M$301M$99M$63M$136M$23M$5M·
Net Change in Cash $-15M$-6M$-194M$-201M$233M$159M$87M$-25M$30M$-7M$-26M$33M
Taxes Paid $3M$2M$1M·········
Free Cash Flow $345M$-53M$-97M$-163M$-145M$-138M$-90M$-93M·$-59M$-18M$-39M
Levered FCF ··$-206M$-263M$-205M$-152M······
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 39.0%-0.56%-31.3%-54.8%-113.1%-981.1%-203.7%-456.2%·-184.4%-81.7%-336.4%
Net Margin 30.2%-19.7%-68.4%-91.2%-117.1%-1026.4%-223.0%-490.2%·-209.2%-89.1%-332.1%
Pretax Margin 30.6%-19.3%-68.3%-90.2%-115.7%-1026.4%······
EBITDA Margin 39.1%-0.29%-30.8%-54.3%-112.6%-976.9%-202.2%-452.5%·-182.6%-81.4%-335.0%
ROA 52.5%-17.6%-42.5%-43.4%-39.9%-71.7%-67.6%-62.3%·-52.0%-32.9%-48.7%
ROE -97.6%18.8%52.3%92.0%144.9%-2543.5%7257.4%-165.8%·-223.7%-69.8%-121.3%
ROIC -282.4%1.6%68.2%238.4%-618.4%-133.9%······
Liquidity & Solvency 5
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 2.12.63.34.95.53.11.81.6·1.21.01.5
Quick Ratio 1.91.11.13.45.12.71.50.4·0.60.50.9
Debt / Equity 0.0-0.7-0.7-0.8-1.3-7.80.80.6·17.90.60.4
LT Debt / Equity 0.0-0.7-0.7-0.8-1.3-6.2······
Interest Coverage ··-1.0-1.5-3.0-12.1-8.4-10.3·-7.5-7.6-9.2
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 1.70.90.60.50.30.10.30.1·0.20.40.1
Inventory Turnover 2.80.40.20.30.60.4···2.21.20.0
Receivables Turnover 9.46.66.26.88.31.23.74.0·3.59.6·
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $-0.56$-2.28$-2.21$-1.57$-0.58$-0.11$0.25$0.45·$0.02$0.65$1.05
Revenue / Share $4.00$2.18$1.72$1.46$0.88$0.11$0.42$0.20·$0.36$0.66·
Cash Flow / Share $1.59$-0.25$-0.49$-0.87$-0.79$-0.82$-0.77$-0.90·$-0.73$-0.18·
Cash / Share $0.42$0.50$0.54$1.62$2.74$1.54$0.74$0.24·$0.30$0.39$0.76
EPS (TTM) $1.21$-0.43$-1.18$-1.33$-1.03$-1.09$-0.61$-0.61$-0.61$-0.61$-0.60·
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 94.1%36.0%22.4%72.3%782.4%·······
Revenue CAGR 3Y 47.8%42.1%165.0%·········
Revenue CAGR 5Y 117.9%···········
Valuation (TTM) 13
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $875M$451M$331M$271M$157M$18M$49M$21M$25M$26M$48M$14M
Net Income TTM $264M$-89M$-227M$-247M$-184M$-183M$-109M$-101M$-66M$-55M$-43M$-45M
Market Cap $1.66B$1.57B$1.23B$2.16B$2.55B$1.32B$532M$888M·$467M$757M$875M
Enterprise Value $1.39B$1.78B$1.43B$2.08B$2.18B$1.20B$447M$891M·$473M$758M$850M
P/E 6.4-17.5-5.1-8.6-13.4-6.8-5.7-13.2-8.0-10.4-17.2·
P/S 1.93.53.78.016.274.010.943.0·17.715.764.3
P/B -13.9-3.3-2.7-7.3-23.9-68.413.918.0·296.015.911.6
P / Cash Flow 4.8-30.1-13.0-13.3-18.0-9.6-5.9-9.6·-8.7-57.7-22.7
P / FCF 4.8-29.5-12.7-13.2-17.7-9.6-5.9-9.6·-8.0-41.5-22.6
EV / EBITDA 4.1-1371.2-14.0-14.2-12.3-6.9-4.5-9.5·-9.8-19.3-18.7
EV / FCF 4.0-33.5-14.6-12.8-15.1-8.7-5.0-9.6·-8.1-41.6-22.0
EV / Revenue 1.63.94.37.713.967.19.243.1·18.015.762.5
Earnings Yield 15.5%-5.7%-19.7%-11.6%-7.4%-14.6%-17.7%-7.6%-12.4%-9.6%-5.8%·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $875M $451M $331M $271M $157M
Operating Margin % 39.0% -0.56% -31.3% -54.8% -113.1%
Net Income $264M $-89M $-227M $-247M $-184M
Diluted EPS $1.21 $-0.43 $-1.18 $-1.33 $-1.03

Institutional owners (13F) 345 filers · $2.8B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 345
Value held $2.8B
New positions 55
Exited positions 34
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
55 (-22 vs prior Q) 34 (-5 vs prior Q) 137 (+20 vs prior Q) 87 (+8 vs prior Q) +4.1M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BlackRock, Inc. $238,930,360 23,893,036 8.46% Shares
VANGUARD GROUP INC $173,732,325 22,273,375 6.15% Shares
RA CAPITAL MANAGEMENT, L.P. $158,271,860 15,827,186 5.61% Shares
STATE STREET CORP $151,910,980 15,191,098 5.38% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $150,964,030 15,096,403 5.35% Shares
VANGUARD CAPITAL MANAGEMENT LLC $113,642,360 11,364,236 4.03% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $111,391,580 11,139,158 3.95% Shares
TCG Crossover Management, LLC $110,209,680 11,020,968 3.90% Shares
PERCEPTIVE ADVISORS LLC $103,088,880 10,308,888 3.65% Shares
JANUS HENDERSON GROUP PLC $84,853,520 8,908,506 3.01% Shares
Vestal Point Capital, LP $83,000,000 8,300,000 2.94% Shares
TWO SIGMA INVESTMENTS, LP $67,753,490 6,775,349 2.40% Shares
GEODE CAPITAL MANAGEMENT, LLC $62,493,232 6,248,046 2.21% Shares
Aberdeen Group plc $53,108,710 5,310,871 1.88% Shares
UBS Group AG $50,782,800 5,078,280 1.80% Shares
BANK OF AMERICA CORP /DE/ $48,012,840 4,801,284 1.70% Shares
GOLDMAN SACHS GROUP INC $44,818,738 4,481,874 1.59% Shares
Frazier Life Sciences Management, L.P. $40,092,400 4,009,240 1.42% Shares
Nuveen, LLC $40,072,370 4,007,237 1.42% Shares
MILLENNIUM MANAGEMENT LLC $33,947,290 3,394,729 1.20% Shares
TWO SIGMA ADVISERS, LP $31,895,074 4,089,112 1.13% Shares
RP Management, LLC $28,846,155 3,846,154 1.02% Shares
JANE STREET GROUP, LLC $27,626,830 2,762,683 0.98% Shares
DIMENSIONAL FUND ADVISORS LP $27,187,810 2,718,781 0.96% Shares
Fisher Asset Management, LLC $26,040,270 2,604,027 0.92% Shares
RENAISSANCE TECHNOLOGIES LLC $25,302,900 2,530,290 0.90% Shares
Kynam Capital Management, LP $25,226,600 2,522,660 0.89% Shares
Candriam S.C.A. $25,125,293 2,514,949 0.89% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $23,532,910 2,353,291 0.83% Shares
RICE HALL JAMES & ASSOCIATES, LLC $23,320,430 2,332,043 0.83% Shares
NORTHERN TRUST CORP $22,557,310 2,255,731 0.80% Shares
AQR CAPITAL MANAGEMENT LLC $22,143,020 2,214,302 0.78% Shares
MORGAN STANLEY $19,996,852 1,999,684 0.71% Shares
Nantahala Capital Management, LLC $19,011,600 1,901,160 0.67% Shares
Eversept Partners, LP $18,656,530 1,865,653 0.66% Shares
ORBIMED ADVISORS LLC $18,520,000 1,852,000 0.66% Shares
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND $18,449,120 1,844,912 0.65% Shares
STIFEL FINANCIAL CORP $18,262,340 1,826,234 0.65% Shares
VANGUARD FIDUCIARY TRUST CO $17,595,730 1,759,573 0.62% Shares
CITADEL ADVISORS LLC $17,591,600 1,759,160 0.62% Shares
JUPITER ASSET MANAGEMENT LTD $16,428,740 1,642,874 0.58% Shares
IMC-Chicago, LLC $16,343,360 1,634,336 0.58% Shares
Parkman Healthcare Partners LLC $16,242,790 1,624,279 0.58% Shares
Legal & General Group Plc $14,555,141 1,455,514 0.52% Shares
OP Asset Management Ltd $13,409,900 1,340,990 0.48% Shares
Invesco Ltd. $12,337,830 1,233,783 0.44% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $11,956,510 1,195,651 0.42% Shares
Pictet Asset Management Holding SA $11,951,392 1,249,771 0.42% Shares
BNP PARIBAS FINANCIAL MARKETS $11,740,520 1,174,052 0.42% Shares
FIRST TRUST ADVISORS LP $11,204,690 1,120,469 0.40% Shares

Show all 345 institutional owners →

Activists & 5%+ owners 15 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Great Point Partners, LLC, Dr. Jeffrey R. Jay, M.D., Mr. David Kroin ×3 filings July 31, 2018 · Initial filing · SEC
RA Capital Management, LLC, Peter Kolchinsky, RA Capital Healthcare Fund, L.P. April 2, 2018 · Initial filing Passive investment SEC
Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker, Felix J. Baker ×5 filings Aug. 16, 2016 · Initial filing · SEC
Baker Bros. Advisors, LLC, Julian C. Baker, Felix J. Baker ×2 filings Oct. 23, 2012 · Initial filing M&A / sale SEC
Julian C. Baker, Felix J. Baker ×4 filings Oct. 13, 2011 · Initial filing · SEC
L. John Doerr III, KPCB Pandemic and Bio Defense Fund, LLC, KPTV, LLC ×2 filings Aug. 20, 2007 · Initial filing · SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Dec. 7, 2005 · Initial filing · SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Dec. 7, 2005 · Initial filing · SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Dec. 7, 2005 · Initial filing · SEC
Undisclosed reporting person Oct. 13, 2005 · Initial filing · SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Feb. 26, 2004 · Initial filing · SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Feb. 25, 2004 · Initial filing · SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Feb. 24, 2004 · Initial filing · SEC
Biotechnology Value Fund, L.P., Investment 10, L.L.C., Biotechnology Value Fund II, L.P., BVF Investments, L.L.C., BVF Partners L.P., BVF Inc. ×2 filings Oct. 31, 2003 · Initial filing · SEC
William W. Featheringill Feb. 14, 2002 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 51 insiders · 21 officers · 30 directors

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Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Babar Ghias Chief Financial Officer Dec. 17, 2025 A 268,700 0 0 $0
Anthony Doyle Chief Financial Officer Dec. 19, 2024 A 377,867 0 0 $0
Thomas R Staab II Senior Vice President and CFO Feb. 21, 2020 A 125,176 0 0 $0
Stuart Grant SR VP & CFO March 16, 2011 M 57,102 0 0 $0
Charles K Gayer President and CCO Dec. 22, 2025 M 952,583 0 0 $0
Claude J Bennett Chief Operating Officer March 14, 2008 A 65,730 0 0 $0
Alane P Barnes Chief Legal Officer May 13, 2026 M 400,703 0 7 $-3,461,969
Sandeep Menon Chief R&D Officer April 6, 2026 A 205,150 0 0 $0
Helen M. Thackray Chief R&D Officer March 31, 2025 F 377,318 0 0 $0
Michael L Jones Exec. Director, Finance - PAO Dec. 19, 2022 A 16,653 0 0 $0
Yarlagadda S Babu Chief Discovery Officer Nov. 14, 2022 M 298,541 0 0 $0
William P Sheridan Chief Medical Officer March 10, 2022 M 37,954 0 0 $0
Megan Sniecinski Chief Business Officer Dec. 15, 2020 A 45,000 0 0 $0
Lynne Powell Senior VP - CCO Jan. 28, 2019 M 0 0 0 $0
David Mccullough VP March 15, 2012 F 24,124 0 0 $0
Robert S Lowrey Controller, PAO Feb. 7, 2011 A 9,766 0 0 $0
Mike Mills Principal Accounting Officer March 12, 2010 M 0 0 0 $0
Michael A Darwin Principal Accounting Officer July 31, 2008 P 3,048 0 0 $0
Jonathan M Nugent VP Corp Communications July 31, 2007 P 508 0 0 $0
James W Alexander SR. VP, Chief Medical Officer July 31, 2007 P 3,659 0 0 $0
Randall B Riggs Senior VP Business Development May 16, 2007 A 1,928 0 0 $0
Amy E Mckee Director Aug. 31, 2026 A 47,821 0 1 $-100,285
Jill C. Milne Director Aug. 31, 2026 A 33,226 0 0 $0
Steven Frank Director Aug. 31, 2026 A 36,747 0 0 $0
Jon P Stonehouse Director Aug. 31, 2026 A 1,340,419 0 0 $0
Vincent Milano Director Aug. 31, 2026 A 109,642 0 0 $0
Theresa Heggie Director June 11, 2026 A 80,646 0 1 $-504,823
Machelle Sanders Director June 11, 2026 A 45,936 0 1 $-68,544
Steven K Galson Director June 11, 2026 A 27,794 0 0 $0
Alan G Levin Director June 11, 2026 A 79,565 0 0 $0
Nancy J Hutson Director June 12, 2025 A 99,138 0 0 $0
George B Abercrombie Director June 12, 2024 A 36,431 0 0 $0
Steve Aselage Director June 12, 2024 A 70,159 0 0 $0
Kenneth B Lee JR Director June 13, 2023 A 68,863 0 0 $0
Robert Alexander Ingram Director Feb. 28, 2023 A 100,198 0 0 $0
Stanley C Erck Director Nov. 28, 2018 M 48,333 0 0 $0
Fred Cohen Director June 20, 2018 A 119,410 0 0 $0
Sanj K Patel Director May 24, 2017 A · 0 0 $0
Charles A Sanders Director Feb. 29, 2016 A 12,971 0 0 $0
Peder Jensen Director May 2, 2014 A 60,000 0 0 $0
John L Higgins Director May 23, 2012 A · 0 0 $0
HOROVITZ ZOLA P Director May 23, 2012 A 3,000 0 0 $0
Stephen R Biggar Director May 12, 2011 A · 0 0 $0
Beth C Seidenberg Director May 13, 2010 A 3,000 0 0 $0
William W Featheringill Director May 13, 2010 A 231,538 0 0 $0
William M Spencer III Director May 16, 2007 A 186,761 0 0 $0
Joseph H Sherrill JR Director May 16, 2007 A 451,900 0 0 $0
Charles E Bugg Director March 18, 2007 A 62,439 0 0 $0
GORDON CARL L Director May 17, 2006 A 1,100,000 0 0 $0
John A Montgomery Director Nov. 4, 2003 M 46,785 0 0 $0
Randolph C Steer · May 21, 2008 A · 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 41 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PBE · Invesco Exchange-Traded Fund Trust 2.35% 1,193,733 SH Oct. 1, 2026 Daily
BBP · ETFis Series Trust I 1.42% 155,993 NS July 31, 2026 N-PORT
ABLS · Abacus FCF ETF Trust 0.99% 510 NS July 31, 2026 N-PORT
JSMD · Janus Detroit Street Trust 0.92% 1,078,429 NS July 31, 2026 N-PORT
JSML · Janus Detroit Street Trust 0.62% 248,560 NS July 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.59% 324,702 NS July 31, 2026 N-PORT
FYC · First Trust Exchange-Traded AlphaDE… 0.36% 516,595 NS July 31, 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0.23% 73,039 SH Oct. 1, 2026 Daily
PWS · Pacer Funds Trust 0.17% 4,436 NS July 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.14% 249,665 SH Aug. 19, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.14% 18,119 SH Oct. 1, 2026 Daily
ESSC · Strategy Shares 0.14% 5,593 NS July 31, 2026 N-PORT
IBB · iShares Trust 0.13% 1,651,139 SH Sept. 11, 2026 Daily
IWO · iShares Trust 0.13% 2,178,966 SH Sept. 11, 2026 Daily
FYX · First Trust Exchange-Traded AlphaDE… 0.11% 174,467 NS July 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.08% 64,429 NS July 31, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.07% 46,799 NS July 31, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.07% 1,339,774 SH Aug. 19, 2026 Daily
RSSL · Global X Funds 0.07% 111,471 NS July 31, 2026 N-PORT
ISCG · iShares Trust 0.06% 75,067 SH Sept. 11, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.06% 207,179 SH Oct. 1, 2026 Daily
IWM · iShares Trust 0.06% 5,937,121 SH Sept. 11, 2026 Daily
DFAS · Dimensional ETF Trust 0.05% 770,732 NS July 31, 2026 N-PORT
VBK · VANGUARD INDEX FUNDS 0.04% 1,696,014 SH Aug. 19, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.03% 2,837,341 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.03% 624,412 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.03% 99,007 NS July 31, 2026 N-PORT
VB · VANGUARD INDEX FUNDS 0.02% 2,922,024 SH Aug. 19, 2026 Daily
WSML · iShares Trust 0.01% 11,812 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 72,998 SH Sept. 11, 2026 Daily
ITOT · iShares Trust 0.00% 336,323 SH Sept. 11, 2026 Daily
DFUS · Dimensional ETF Trust 0.00% 52,194 NS July 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 36,571 NS July 31, 2026 N-PORT
TILT · FlexShares Trust 0.00% 632 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 286 NS July 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 8,070,274 SH Aug. 19, 2026 Daily
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.00% 196,622 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 19,676 SH Aug. 19, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.00% 51,624 SH Aug. 19, 2026 Daily
ISCB · iShares Trust · 10,494 SH Sept. 11, 2026 Daily
SMLF · iShares Trust · 766,086 SH Sept. 11, 2026 Daily

BCRX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 17 analysts BUY
Median target $17.00 +108.1%
5 29.4% Strong Buy
10 58.8% Buy
2 11.8% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

11 analysts · 2026-09-28

Mean target $20.64 +152.6%

← Below all targets Current price $8.17
Low$11.00 Mean$20.64 High$32.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
BCRX $1.66B 6.4 94.1% 30.2% -97.6% ·
RXRX $2.16B -2.8 26.9% -863.4% -62.9% ·
VERA · -10.9 · · -55.9% ·
MLYS $2.96B -15.8 · · -32.2% ·
ZBIO $1.98B -4.3 100.0% -3777.4% -156.8% ·
VCEL $1.82B 112.5 16.4% 6.0% 5.0% 74.4%
BHVN $1.50B -1.6 · · -310.8% ·
AGIO $1.59B -3.8 48.0% -764.0% -32.2% ·
VIR $841M -1.9 -7.6% -638.9% -51.1% ·
PVLA $1.30B -28.2 65.3% -1610.6% -110.1% ·

Latest News Recent headlines mentioning this company

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Source: SEC 10-Q filed Aug 5, 2026