GPCR Structure Therapeutics Inc. - American Depositary Shares
$54,90
Prix · Aoû 18, 2026
Données fondamentales au Aoû 6, 2026
Fourchette 52 semaines
$18–$95
48% of range
Note des analystes
BUY
23 analysts
Objectif de cours
$105
+91% upside
P/E (TTM)
-68.6
ROE
-12.3%
Marge nette
—
GPCR Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$54.90
Capitalisation Boursière
$11.67B
P/E (TTM)
-68.6
BPA (TTM)
$-0.80
Revenus (TTM)
—
Rendement div.
—
ROE
-12.3%
Dette/Capitaux propres
—
Fourchette 52 semaines
$18 – $95
GPCR Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
—
BPA
$-0.80
2022-12-31
→
2025-12-31
Flux de trésorerie libre
$-226M
2023-12-31
→
2025-12-31
Marges
—
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
GPCR
Médiane des pairs
P/E (TTM)
-68.6
38.7
P/B
7.7
3.8
Price / FCF (Cours / FCF)
-51.7
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
GPCR
Médiane des pairs
ROA
-11.3%
-6.4%
ROE
-12.3%
-16.8%
ROIC
-11.7%
—
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
GPCR
Médiane des pairs
Current Ratio (Ratio de liquidité)
24.8
12.8
Quick Ratio (Ratio de liquidité réduite)
22.9
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
GPCR
Médiane des pairs
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
GPCR
Médiane des pairs
GPCR Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
23 analystes
- Achat fort 8 34,8%
- Achat 13 56,5%
- Conserver 2 8,7%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
15 analystes · 2026-08-14
Médiane
$104.00
← En dessous de tous les objectifs
$54.90
Bas
$69.50
Haut
$145.00
Objectif médian
$104.00
+89,5%
Objectif moyen
$105.10
+91,5%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
-0.49%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.49 | $-0.41 | -0.08% |
| 31 mars 2026 | $-0.35 | $-0.35 | 0.00% |
| 31 décembre 2025 | $-1.22 | $-0.47 | -0.75% |
| 30 septembre 2025 | $-1.11 | $-0.36 | -0.75% |
| 30 juin 2025 | $-1.08 | $-0.28 | -0.80% |
| 31 mars 2025 | $-0.81 | $-0.23 | -0.58% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| LGND | $3.74B | 30.8 | 60.4% | 46.4% | 13.5% | — |
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| MANE | — | — | — | — | 82.6% | — |
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
| MBX | $1.42B | -13.3 | — | — | -29.6% | — |
| ALMS | — | -3.4 | — | -1011.8% | -61.9% | — |
| AMLX | $1.33B | -7.9 | -77.1% | — | -61.2% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 12
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| R&D Expense | $225M | $109M | $70M | $36M | |
| SG&A Expense | $62M | $49M | $33M | $16M | |
| Operating Expenses | $177M | $158M | $103M | $53M | |
| Operating Income | $-177M | $-158M | $-103M | $-53M | |
| Pretax Income | $-141M | $-122M | $-89M | $-51M | |
| Income Tax | $515.0K | $310.0K | $236.0K | $17.0K | |
| Net Income | $-141M | $-123M | $-90M | $-51M | |
| EPS (Basic) | $-0.80 | $-0.78 | $-0.81 | $-5.51 | |
| EPS (Diluted) | $-0.80 | $-0.78 | $-0.81 | $-5.51 | |
| Shares (Basic) | 177,596,000 | 157,922,000 | 110,198,000 | 9,584,000 | |
| Shares (Diluted) | 177,596,000 | 157,922,000 | 110,198,000 | 9,584,000 | |
| EBITDA | $-177M | $-158M | $-103M | · |
Bilan 21
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $800M | $170M | $130M | $26M | |
| Short-term Investments | $647M | $714M | $338M | $65M | |
| Prepaid Expense | $24M | $8M | $6M | $2M | |
| Current Assets | $1.57B | $891M | $474M | $93M | |
| PP&E (Net) | $7M | $3M | $3M | $1M | |
| PP&E (Gross) | $10M | $5M | $4M | $1M | |
| Accum. Depreciation | $3M | $2M | $644.0K | $349.0K | |
| Other Non-current Assets | $717.0K | $5M | $45.0K | $3M | |
| Total Assets | $1.58B | $903M | $482M | $98M | |
| Accounts Payable | $14M | $8M | $5M | $6M | |
| Current Liabilities | $63M | $36M | $25M | $13M | |
| Capital Leases | $4M | $2M | $4M | · | |
| Other Non-current Liabilities | $647.0K | $302.0K | $298.0K | · | |
| Total Liabilities | $68M | $38M | $29M | $13M | |
| Common Stock | $21.0K | $17.0K | $14.0K | $1.0K | |
| Paid-in Capital | $1.99B | $1.19B | $659M | $2M | |
| Retained Earnings | $-470M | $-329M | $-207M | $-117M | |
| AOCI | $1M | $914.0K | $521.0K | $-110.0K | |
| Stockholders' Equity | $1.52B | $865M | $453M | $-115M | |
| Liabilities + Equity | $1.58B | $903M | $482M | $98M | |
| Shares Outstanding | 212,513,000 | 171,860,000 | 139,220,000 | 10,527,000 |
Flux de trésorerie 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $29M | $19M | $8M | $3M | |
| Operating Cash Flow | $-222M | $-117M | $-79M | $-46M | |
| CapEx | $4M | $1M | $2M | $155.0K | |
| Investing Cash Flow | $90M | $-359M | $-268M | $-62M | |
| Stock Issued | · | $515M | · | · | |
| Net Stock Activity | · | $515M | · | · | |
| Financing Cash Flow | $763M | $515M | $452M | $29M | |
| Net Change in Cash | $630M | $40M | $104M | $-79M | |
| Taxes Paid | $634.0K | $370.0K | $12.0K | · | |
| Free Cash Flow | $-226M | $-118M | $-82M | · |
Rentabilité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| ROA | -11.3% | -17.7% | -30.9% | · | |
| ROE | -12.3% | -13.9% | -27.8% | · | |
| ROIC | -11.7% | -18.3% | -22.8% | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 24.8 | 24.7 | 19.1 | · | |
| Quick Ratio | 22.9 | 24.5 | 18.9 | · |
Valorisation (TTM) 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Net Income TTM | $-141M | $-123M | $-90M | $-51M | |
| Market Cap | $14.78B | $4.66B | $5.67B | · | |
| P/E | -86.9 | -34.8 | -50.3 | · | |
| P/B | 9.7 | 5.4 | 12.5 | · | |
| P / Tangible Book | 9.7 | 5.4 | 12.5 | · | |
| P / Cash Flow | -66.5 | -40.0 | -71.4 | · | |
| P / FCF | -65.5 | -39.5 | -69.5 | · | |
| Earnings Yield | -1.1% | -2.9% | -2.0% | · |
Compte de résultat 12
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $100M | $67M | $69M | $59M | $55M | $43M | $33M | $33M | $22M | $21M | $18M | $19M | $13M | $8M | $10M | $8M | |
| SG&A Expense | $19M | $23M | $18M | $15M | $16M | $13M | $14M | $13M | $11M | $11M | $9M | $7M | $7M | $5M | $4M | $4M | |
| Operating Expenses | $119M | $89M | $-24M | $74M | $70M | $56M | $47M | $46M | $33M | $32M | $26M | $26M | $20M | $13M | $14M | $13M | |
| Operating Income | $-119M | $-89M | $24M | $-74M | $-70M | $-56M | $-47M | $-46M | $-33M | $-32M | $-26M | $-26M | $-20M | $-13M | $-14M | $-13M | |
| Pretax Income | $-106M | $-76M | $33M | $-66M | $-62M | $-47M | $-36M | $-34M | $-26M | $-26M | $-23M | $-23M | $-18M | $-12M | $-14M | $-13M | |
| Income Tax | $234.0K | $190.0K | $170.0K | $108.0K | $139.0K | $98.0K | $136.0K | $92.0K | $53.0K | $29.0K | $405.0K | $118.0K | $25.0K | $-180.0K | $64.0K | $60.0K | |
| Net Income | $-106M | $-76M | $33M | $-66M | $-62M | $-47M | $-36M | $-34M | $-26M | $-26M | $-24M | $-23M | $-18M | $-12M | $-14M | $-13M | |
| EPS (Basic) | $-0.49 | $-0.35 | $0.20 | $-0.37 | $-0.36 | $-0.27 | $-0.21 | $-0.20 | $-0.18 | $-0.19 | $-0.21 | $-0.20 | $-0.25 | $-1.16 | $-1.64 | $-1.44 | |
| EPS (Diluted) | $-0.49 | $-0.35 | $0.20 | $-0.37 | $-0.36 | $-0.27 | $-0.21 | $-0.20 | $-0.18 | $-0.19 | $-0.21 | $-0.20 | $-0.25 | $-1.16 | $-1.64 | $-1.44 | |
| Shares (Basic) | 217,957,000 | 217,326,000 | -342,571,000 | 175,469,000 | 172,647,000 | 172,051,000 | -301,657,000 | 171,630,000 | 148,239,000 | 139,710,000 | 114,948,000 | 114,759,000 | 71,655,000 | -18,694,000 | 9,435,000 | 9,063,000 | |
| Shares (Diluted) | 217,957,000 | 217,326,000 | 4,194,000 | 175,469,000 | 172,647,000 | 172,051,000 | -301,657,000 | 171,630,000 | 148,239,000 | 139,710,000 | 114,948,000 | 114,759,000 | 71,655,000 | -18,694,000 | 9,435,000 | 9,063,000 | |
| EBITDA | $-119M | $-89M | · | $-74M | $-70M | $-56M | · | $-46M | $-33M | $-32M | $-26M | $-26M | $-20M | · | · | · |
Bilan 21
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $273M | $316M | $800M | $103M | $147M | $152M | $170M | $172M | $382M | $98M | $51M | $41M | $126M | $26M | · | · | |
| Short-term Investments | $1.07B | $1.14B | $647M | $696M | $639M | $685M | $714M | $743M | $545M | $339M | $155M | $184M | $114M | $65M | · | · | |
| Prepaid Expense | $29M | $32M | $24M | $15M | $13M | $13M | $8M | $8M | $11M | $13M | $5M | $4M | $5M | $2M | · | · | |
| Current Assets | $1.37B | $1.49B | $1.57B | $814M | $799M | $850M | $891M | $924M | $938M | $449M | $210M | $228M | $246M | $93M | · | · | |
| PP&E (Net) | $6M | $6M | $7M | $5M | $3M | $4M | $3M | $4M | $3M | $3M | $2M | $1M | $961.0K | $1M | · | · | |
| PP&E (Gross) | · | · | $10M | · | · | · | $5M | $5M | $4M | $4M | $3M | $2M | $1M | $1M | · | · | |
| Accum. Depreciation | · | · | $3M | · | · | · | $2M | $1M | $1M | $866.0K | $572.0K | $493.0K | $419.0K | $349.0K | · | · | |
| Other Non-current Assets | $41M | $6M | $717.0K | $7M | $6M | $6M | $5M | $2M | $2M | $47.0K | $350.0K | $38.0K | $59.0K | $3M | · | · | |
| Total Assets | $1.43B | $1.51B | $1.58B | $832M | $816M | $867M | $903M | $933M | $947M | $457M | $216M | $229M | $247M | $98M | · | · | |
| Accounts Payable | $11M | $8M | $14M | $18M | $9M | $9M | $8M | $8M | $2M | $7M | $3M | $6M | $5M | $6M | · | · | |
| Current Liabilities | $66M | $57M | $63M | $58M | $39M | $36M | $36M | $33M | $23M | $24M | $20M | $15M | $11M | $13M | · | · | |
| Capital Leases | $4M | $3M | $4M | $4M | $5M | $5M | $2M | $3M | $3M | $4M | $3M | · | · | · | · | · | |
| Other Non-current Liabilities | $1M | $863.0K | $647.0K | $325.0K | $317.0K | $308.0K | $302.0K | $309.0K | $293.0K | $296.0K | $281.0K | · | · | · | · | · | |
| Total Liabilities | $71M | $61M | $68M | $62M | $44M | $42M | $38M | $36M | $26M | $27M | $23M | $15M | $11M | $13M | · | · | |
| Common Stock | $21.0K | $21.0K | $21.0K | $18.0K | $17.0K | $17.0K | $17.0K | $17.0K | $17.0K | $14.0K | · | · | $11.0K | $1.0K | · | · | |
| Paid-in Capital | $2.01B | $2.00B | $1.99B | $1.27B | $1.21B | $1.20B | $1.19B | $1.19B | $1.18B | $663M | $375M | $373M | $371M | $2M | · | · | |
| Retained Earnings | $-652M | $-546M | $-470M | $-503M | $-438M | $-376M | $-329M | $-293M | $-259M | $-233M | $-182M | $-158M | $-135M | $-117M | · | · | |
| AOCI | $-3M | $-2M | $1M | $825.0K | $362.0K | $815.0K | $914.0K | $3M | $-487.0K | $-90.0K | $-310.0K | $-390.0K | $147.0K | $-110.0K | · | · | |
| Stockholders' Equity | $1.35B | $1.45B | $1.52B | $770M | $772M | $825M | $865M | $897M | $921M | $430M | $193M | $214M | $236M | $-115M | · | · | |
| Liabilities + Equity | $1.43B | $1.51B | $1.58B | $832M | $816M | $867M | $903M | $933M | $947M | $457M | $216M | $229M | $247M | $98M | · | · | |
| Shares Outstanding | 213,655,000 | 213,208,000 | 212,513,000 | 182,033,000 | 172,700,000 | 172,610,000 | 171,860,000 | 171,762,000 | 171,589,000 | 139,855,000 | · | · | 114,730,000 | 10,527,000 | · | · |
Flux de trésorerie 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $13M | $12M | $8M | $7M | $8M | $6M | $6M | $6M | $4M | $3M | $2M | $2M | $3M | $623.0K | $643.0K | $620.0K | |
| Operating Cash Flow | $-120M | $15M | $-64M | $-51M | $-55M | $-52M | $-36M | $-20M | $-26M | $-34M | $-21M | $-17M | $-20M | $-12M | $-10M | $-14M | |
| CapEx | $-42.0K | $1M | $1M | $2M | $232.0K | $314.0K | $16.0K | $685.0K | $427.0K | $162.0K | $820.0K | · | · | $71.0K | $-53.0K | $65.0K | |
| Investing Cash Flow | $74M | $-497M | $56M | $-49M | $49M | $34M | $33M | $-189M | $-205M | $1M | $30M | $-69M | $-49M | $10M | $-16M | $-40M | |
| Stock Issued | · | · | · | · | · | · | · | $0 | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $2M | $-2M | $705M | $56M | $517.0K | $809.0K | $615.0K | $-757.0K | $515M | $702.0K | $473.0K | $-297.0K | $170M | $-316.0K | $31M | $-1M | |
| Net Change in Cash | $-44M | $-483M | $697M | $-44M | $-5M | $-17M | $-3M | $-209M | $284M | $-32M | $10M | $-86M | $100M | $-2M | $5M | $-55M | |
| Free Cash Flow | · | $14M | · | · | · | $-53M | · | · | · | $-34M | · | · | · | · | · | · |
Rentabilité 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -9.5% | -6.4% | · | -7.4% | -7.0% | -7.1% | · | -5.9% | -4.4% | -7.4% | -22.1% | · | -14.5% | · | · | · | |
| ROE | -10.0% | -6.7% | · | -7.9% | -7.3% | -7.5% | · | -6.2% | -4.6% | -7.8% | -24.7% | · | -15.2% | · | · | · | |
| ROIC | -8.8% | -6.2% | · | -9.6% | -9.2% | -6.8% | · | -5.1% | -3.6% | -7.5% | -13.8% | -12.2% | -8.3% | · | · | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 20.8 | 26.2 | · | 14.2 | 20.5 | 23.3 | · | 27.6 | 41.4 | 19.1 | 10.5 | 15.2 | 22.4 | · | · | · | |
| Quick Ratio | 20.3 | 25.6 | · | 13.9 | 20.1 | 22.9 | · | 27.4 | 40.9 | 18.5 | 10.2 | 15.0 | 21.9 | · | · | · |
Valorisation (TTM) 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-310M | $-250M | · | $-208M | $-169M | $-133M | · | $-110M | $-99M | $-91M | $-78M | $-68M | $-57M | · | · | · | |
| Market Cap | $11.47B | $10.28B | · | $5.10B | $3.58B | $2.99B | · | $7.54B | $6.74B | $5.99B | · | · | $2.73B | · | · | · | |
| P/E | -34.2 | · | · | · | -24.7 | -20.6 | · | -56.3 | -50.3 | -50.4 | -26.1 | -12.4 | -5.2 | · | · | · | |
| P/B | 8.5 | 7.1 | · | 6.6 | 4.6 | 3.6 | · | 8.4 | 7.3 | 13.9 | · | · | 11.5 | · | · | · | |
| P / Tangible Book | 8.5 | 7.1 | · | 6.6 | 4.6 | 3.6 | · | 8.4 | 7.3 | 13.9 | · | · | 11.5 | · | · | · | |
| P / Cash Flow | · | 674.6 | · | · | · | -57.2 | · | · | · | -175.9 | · | · | -134.4 | · | · | · | |
| P / FCF | · | 731.3 | · | · | · | -56.9 | · | · | · | -175.1 | · | · | · | · | · | · | |
| Earnings Yield | -2.9% | · | · | · | -4.0% | -4.9% | · | -1.8% | -2.0% | -2.0% | -3.8% | -8.1% | -19.3% | · | · | · |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Résultat net | $-141M | $-123M | $-90M | $-51M |
| BPA dilué | $-0.80 | $-0.78 | $-0.81 | $-5.51 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Ratio de liquidité | 24.8 | 24.7 | 19.1 | — |
| Ratio de liquidité réduite | 22.9 | 24.5 | 18.9 | — |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Flux de trésorerie libre | $-226M | $-118M | $-82M | — |
Dernières actualités Actualités récentes mentionnant cette entreprise
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Détenteurs institutionnels (13F) 205 déclarants · $2.9B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 32 (-8 vs T. préc.) | 28 (-10 vs T. préc.) | 71 (+3 vs T. préc.) | 58 (-9 vs T. préc.) | -489K |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | $351 836 637 | 6 555 555 | 12,01% | Actions |
| FMR LLC | $345 296 142 | 6 433 690 | 11,78% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $340 675 263 | 6 347 592 | 11,63% | Actions |
| Deep Track Capital, LP | $254 399 664 | 4 740 072 | 8,68% | Actions |
| BVF INC/IL | $180 697 390 | 3 366 823 | 6,17% | Actions |
| ORBIMED ADVISORS LLC | $118 578 498 | 2 209 400 | 4,05% | Actions |
| PRINCIPAL FINANCIAL GROUP INC | $94 070 254 | 1 752 753 | 3,21% | Actions |
| AMERICAN CENTURY COMPANIES INC | $90 282 956 | 1 682 179 | 3,08% | Actions |
| RTW INVESTMENTS, LP | $86 274 901 | 1 607 507 | 2,94% | Actions |
| Driehaus Capital Management LLC | $83 361 264 | 1 553 219 | 2,84% | Actions |
| BAKER BROS. ADVISORS LP | $76 883 831 | 1 432 529 | 2,62% | Actions |
| Casdin Capital, LLC | $63 062 250 | 1 175 000 | 2,15% | Actions |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $58 285 620 | 1 086 000 | 1,99% | Actions |
| CAPITOLIS LIQUID GLOBAL MARKETS LLC | $55 875 837 | 1 041 100 | 1,91% | Actions |
| Siren, L.L.C. | $46 852 139 | 872 967 | 1,60% | Actions |
| Pacific Heights Asset Management LLC | $42 936 000 | 800 000 | 1,47% | Actions |
| Rock Springs Capital Management LP | $34 365 813 | 640 317 | 1,17% | Actions |
| Aberdeen Group plc | $34 344 238 | 639 915 | 1,17% | Actions |
| ALLIANCEBERNSTEIN L.P. | $29 484 326 | 611 708 | 1,01% | Actions |
| Logos Global Management LP | $26 835 000 | 500 000 | 0,92% | Actions |
| Parkman Healthcare Partners LLC | $26 065 426 | 485 661 | 0,89% | Actions |
| Davern Capital Partners, LP | $23 939 987 | 446 059 | 0,82% | Actions |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $22 476 996 | 418 800 | 0,77% | Actions |
| DEUTSCHE BANK AG\ | $17 811 302 | 331 867 | 0,61% | Actions |
| NEXTBio Capital Management LP | $16 771 660 | 312 496 | 0,57% | Actions |
| Catalio Capital Management, LP | $14 842 438 | 276 550 | 0,51% | Actions |
| MARSHALL WACE, LLP | $14 361 663 | 267 592 | 0,49% | Actions |
| HSG Holding Ltd | $13 672 433 | 254 750 | 0,47% | Actions |
| SEB Asset Management AB | $13 151 433 | 245 043 | 0,45% | Actions |
| BANK OF AMERICA CORP /DE/ | $12 579 336 | 234 383 | 0,43% | Actions |
| GOLDMAN SACHS GROUP INC | $12 520 889 | 233 294 | 0,43% | Actions |
| NATIONAL BANK OF CANADA /FI/ | $11 581 986 | 215 800 | 0,40% | Actions |
| TWO SIGMA INVESTMENTS, LP | $10 957 053 | 204 156 | 0,37% | Actions |
| Eversept Partners, LP | $10 535 528 | 196 302 | 0,36% | Actions |
| Schonfeld Strategic Advisors LLC | $10 234 062 | 190 685 | 0,35% | Actions |
| Woodline Partners LP | $8 254 875 | 153 808 | 0,28% | Actions |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $8 218 000 | 153 119 | 0,28% | Actions |
| ArrowMark Colorado Holdings LLC | $8 081 575 | 150 579 | 0,28% | Actions |
| Susquehanna Portfolio Strategies, LLC | $7 994 039 | 148 948 | 0,27% | Actions |
| CenterBook Partners LP | $7 944 770 | 148 030 | 0,27% | Actions |
| Rhenman & Partners Asset Management AB | $7 787 517 | 145 100 | 0,27% | Actions |
| GOLDMAN SACHS GROUP INC | $7 782 150 | 145 000 | 0,27% | Option d'achat |
| B Group, Inc. | $7 513 800 | 140 000 | 0,26% | Actions |
| HighVista Strategies LLC | $7 019 177 | 130 784 | 0,24% | Actions |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $6 745 728 | 125 689 | 0,23% | Actions |
| Squarepoint Ops LLC | $6 739 610 | 125 575 | 0,23% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6 566 202 | 122 344 | 0,22% | Actions |
| D. E. Shaw & Co., Inc. | $6 188 151 | 115 300 | 0,21% | Actions |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $6 027 141 | 112 300 | 0,21% | Actions |
| Soleus Capital Management, L.P. | $5 742 690 | 107 000 | 0,20% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5 302 596 | 98 800 | 0,18% | Option d'achat |
| Avidity Partners Management LP | $5 259 660 | 98 000 | 0,18% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $5 215 811 | 97 183 | 0,18% | Actions |
| Qube Research & Technologies Ltd | $5 012 939 | 93 403 | 0,17% | Actions |
| PEREGRINE CAPITAL MANAGEMENT LLC | $4 949 930 | 92 229 | 0,17% | Actions |
| PFM Health Sciences, LP | $4 913 489 | 91 550 | 0,17% | Actions |
| PLATINUM INVESTMENT MANAGEMENT LTD | $4 849 782 | 90 363 | 0,17% | Actions |
| MILLENNIUM MANAGEMENT LLC | $4 807 115 | 89 568 | 0,16% | Actions |
| ExodusPoint Capital Management, LP | $4 200 536 | 78 266 | 0,14% | Actions |
| Boxer Capital Management, LLC | $4 025 250 | 75 000 | 0,14% | Actions |
| Cormorant Asset Management, LP | $4 025 250 | 75 000 | 0,14% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4 025 250 | 75 000 | 0,14% | Actions |
| CITADEL ADVISORS LLC | $4 014 516 | 74 800 | 0,14% | Option d'achat |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3 869 607 | 72 100 | 0,13% | Option de vente |
| ALPS ADVISORS INC | $3 855 277 | 71 833 | 0,13% | Actions |
| TD Asset Management Inc | $3 701 191 | 68 962 | 0,13% | Actions |
| Point72 Europe (London) LLP | $3 267 516 | 116 697 | 0,11% | Actions |
| Brevan Howard Capital Management LP | $3 258 144 | 60 336 | 0,11% | Actions |
| Burkehill Global Management, LP | $3 220 200 | 60 000 | 0,11% | Actions |
| JANE STREET GROUP, LLC | $3 026 988 | 56 400 | 0,10% | Option d'achat |
| CITADEL ADVISORS LLC | $2 908 914 | 54 200 | 0,10% | Option de vente |
| TUDOR INVESTMENT CORP ET AL | $2 879 718 | 53 656 | 0,10% | Actions |
| ANTIPODES PARTNERS Ltd | $2 751 232 | 51 262 | 0,09% | Actions |
| SCOGGIN MANAGEMENT LP | $2 683 500 | 50 000 | 0,09% | Option d'achat |
| Buckland Partners Management Co LLC | $2 683 500 | 50 000 | 0,09% | Actions |
| SEVEN GRAND MANAGERS, LLC | $2 683 500 | 50 000 | 0,09% | Actions |
| DAFNA Capital Management LLC | $2 495 655 | 46 500 | 0,09% | Actions |
| Mariner, LLC | $2 484 116 | 46 285 | 0,08% | Actions |
| STATE STREET CORP | $2 395 238 | 44 629 | 0,08% | Actions |
| VOYA INVESTMENT MANAGEMENT LLC | $2 383 485 | 44 410 | 0,08% | Actions |
| BANQUE PICTET & CIE SA | $2 325 628 | 43 332 | 0,08% | Actions |
| Jump Financial, LLC | $2 289 455 | 42 658 | 0,08% | Actions |
| Cinctive Capital Management LP | $2 193 869 | 40 877 | 0,07% | Actions |
| Jefferies Financial Group Inc. | $2 180 344 | 40 625 | 0,07% | Actions |
| Jones Hill Capital LP | $2 177 231 | 40 567 | 0,07% | Actions |
| AMERIPRISE FINANCIAL INC | $2 117 656 | 39 457 | 0,07% | Actions |
| OSAIC HOLDINGS, INC. | $2 115 279 | 39 414 | 0,07% | Actions |
| STEMPOINT CAPITAL LP | $2 049 013 | 38 178 | 0,07% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2 045 256 | 38 108 | 0,07% | Actions |
| CAPITAL FUND MANAGEMENT S.A. | $2 000 871 | 37 281 | 0,07% | Actions |
| PSquared Asset Management AG | $1 996 524 | 37 200 | 0,07% | Actions |
| FLAX POND CAPITAL, LLC | $1 932 120 | 36 000 | 0,07% | Actions |
| TrueMark Investments, LLC | $1 803 312 | 33 600 | 0,06% | Actions |
| NOMURA ASSET MANAGEMENT CO LTD | $1 759 839 | 32 790 | 0,06% | Actions |
| DCF Advisers, LLC | $1 722 807 | 32 100 | 0,06% | Actions |
| EXCHANGE TRADED CONCEPTS, LLC | $1 651 587 | 30 773 | 0,06% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $1 534 962 | 28 600 | 0,05% | Actions |
| Verition Fund Management LLC | $1 530 615 | 28 519 | 0,05% | Actions |
| Y-Intercept (Hong Kong) Ltd | $1 479 843 | 27 573 | 0,05% | Actions |
| Seven Fleet Capital Management LP | $1 441 572 | 26 800 | 0,05% | Actions |
Initiés de la société 15 initiés · 4 dirigeants · 8 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Raymond C Stevens | Chief Executive Officer | 7 février 2023 P | — | 0 | 0 | $0 |
| Jun Yoon | Chief Financial Officer | 7 février 2023 P | — | 0 | 0 | $0 |
| Mark Allen Bach | Chief Medical Officer | 7 février 2023 P | — | 0 | 0 | $0 |
| Melita Sun Jung | Chief Business Officer | 7 février 2023 P | — | 0 | 0 | $0 |
| Joanne Waldstreicher | Administrateur | 17 juin 2026 A | — | 0 | 0 | $0 |
| Angus C. Russell | Administrateur | 17 juin 2026 A | — | 0 | 0 | $0 |
| Sharon Tetlow | Administrateur | 17 juin 2026 A | — | 0 | 0 | $0 |
| Daniel G Welch | Administrateur | 17 juin 2026 A | 123 508 | 0 | 0 | $0 |
| Eric Dobmeier | Administrateur | 17 juin 2026 A | — | 0 | 0 | $0 |
| Ted W Love | Administrateur | 17 juin 2026 A | — | 0 | 0 | $0 |
| Ramy Farid | Administrateur | 7 février 2023 P | 3 260 495 | 0 | 0 | $0 |
| FMR LLC | Détenteur de 10% | 22 juillet 2026 S | 4 769 404 | 0 | 22 | $-7 057 088 |
| John Joseph Berrios | — | 6 août 2026 A | 140 766 | 0 | 0 | $0 |
| Xichen Lin | — | 4 août 2026 S | 228 960 | 0 | 5 | $-983 084 |
| FIL Ltd | — | 7 février 2023 C | 624 239 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Détention d'ETF Détenu par 14 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1,78% | 73 020 NS | 31 mai 2026 | N-PORT |
| MID · AMERICAN CENTURY ETF TRUST | 0,70% | 17 825 NS | 31 mai 2026 | N-PORT |
| FDG · AMERICAN CENTURY ETF TRUST | 0,57% | 59 428 NS | 31 mai 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,46% | 4 115 NS | 30 avril 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 0,44% | 4 628 NS | 31 mai 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,35% | 4 583 NS | 31 mai 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,28% | 4 244 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,24% | 430 126 SH | 8 août 2026 | Quotidien |
| GDOC · Goldman Sachs ETF Trust | 0,20% | 1 008 NS | 31 mai 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,19% | 2 531 NS | 31 mai 2026 | N-PORT |
| BIB · ProShares Trust | 0,15% | 2 880 NS | 31 mai 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,13% | 40 344 NS | 30 avril 2026 | N-PORT |
| APIE · Trust for Professional Managers | 0,02% | 4 104 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 20 734 NS | 31 mai 2026 | N-PORT |