MDGL Madrigal Pharmaceuticals, Inc. - Common Stock
MDGL Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
MDGL Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
MDGL Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 5 20,8%
- Achat 16 66,7%
- Conserver 3 12,5%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
16 analystes · 2026-08-20Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-1.99 | $-2.62 | 0.63% |
| 31 mars 2026 | $-3.25 | $-4.11 | 0.86% |
| 31 décembre 2025 | $-2.57 | $-0.69 | -1.9% |
| 30 septembre 2025 | $-4.96 | $-2.12 | -2.8% |
| 30 juin 2025 | $-1.90 | $-3.71 | 1.8% |
| 31 mars 2025 | $-3.32 | $-3.84 | 0.52% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| MDGL | $13.30B | -45.3 | 432.1% | -30.1% | -44.4% | — |
| BBIO | $14.90B | -20.2 | 126.3% | -146.0% | 41.2% | — |
| NBIX | $14.20B | 30.4 | 21.4% | 16.7% | 16.1% | — |
| EXEL | $11.44B | 15.7 | 7.0% | 33.7% | 37.3% | — |
| BMRN | $11.43B | 33.0 | 12.9% | 10.8% | 5.8% | — |
| ARWR | $4.68B | -3449.0 | 23258.2% | -0.20% | -0.50% | — |
| HALO | $7.93B | 26.3 | 37.5% | 22.7% | 166.1% | — |
| CYTK | $7.81B | -9.7 | 376.6% | -891.6% | 152.7% | — |
| PRAX | $7.43B | -21.9 | 249.5% | — | -47.3% | — |
| SMMT | $13.56B | -12.1 | — | — | -235.1% | — |
| KYMR | $6.33B | -21.1 | -16.7% | -794.0% | -24.4% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 15
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $958M | $180M | $0 | $0 | $0 | · | $0 | $0 | $0 | · | · | · | |
| Cost of Revenue | · | $6M | $0 | $0 | · | · | · | · | · | · | · | · | |
| SG&A Expense | $814M | $435M | $108M | $48M | $37M | $22M | $23M | $15M | $8M | $9M | $805.8K | $16M | |
| Operating Expenses | $1.26B | $678M | $380M | $294M | $242M | $207M | $95M | $41M | $32M | $25M | $3M | $84M | |
| Operating Income | $-300M | $-498M | $-380M | $-294M | $-242M | $-207M | $-95M | $-41M | $-32M | $-25M | $-3M | $-84M | |
| Interest Expense | · | · | $13M | $4M | $0 | $0 | · | · | · | $1M | $4M | · | |
| Interest Income | $37M | $47M | $20M | $2M | $363.0K | · | · | · | · | · | · | · | |
| Other Non-op | $-463.0K | $0 | $0 | · | · | · | · | · | · | · | · | · | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | · | · | · | · | |
| Net Income | $-288M | $-466M | $-374M | $-295M | $-242M | $-202M | $-84M | $-33M | $-31M | $-26M | · | · | |
| EPS (Basic) | $-10.15 | $-17.31 | $-17.33 | $-17.23 | $-14.63 | $-13.09 | · | · | · | · | · | · | |
| EPS (Diluted) | $-10.15 | $-17.31 | $-17.33 | $-17.23 | $-14.63 | $-13.09 | · | · | · | · | · | · | |
| Shares (Basic) | 28,409,706 | 26,908,070 | 21,562,581 | 17,137,201 | 16,535,188 | 15,446,638 | · | · | · | · | · | · | |
| Shares (Diluted) | 28,409,706 | 26,908,070 | 21,562,581 | 17,137,201 | 16,535,188 | 15,446,638 | · | · | · | · | · | · | |
| EBITDA | $-299M | $-497M | $-380M | $-293M | $-242M | $-206M | $-95M | · | $-32M | $-25M | · | $-83M |
Bilan 25
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $199M | $100M | $100M | $332M | $36M | $54M | $47M | $57M | $149M | $19M | $306.0K | $148.1K | |
| Short-term Investments | · | · | · | · | · | · | · | · | $43M | $21M | $32M | $52M | |
| Receivables | $134M | $54M | $0 | · | · | · | · | · | · | · | · | · | |
| Inventory | $75M | $34M | $0 | · | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $48M | $14M | $3M | $3M | $1M | $1M | $1M | $1M | $485.0K | $707.0K | $50.0K | $2M | |
| Current Assets | $1.25B | $1.03B | $637M | $361M | $272M | $285M | $440M | $485M | $192M | $41M | $363.6K | $99M | |
| PP&E (Net) | $1M | $2M | $2M | $601.0K | $851.0K | $1M | $1M | $227.0K | $301.0K | $3.0K | $420.0K | $1M | |
| PP&E (Gross) | · | · | · | · | · | · | · | · | · | · | $22M | $22M | |
| Accum. Depreciation | · | · | · | · | · | · | · | · | · | · | $21M | $20M | |
| Intangibles | $7M | $5M | $0 | · | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $0 | · | · | · | · | · | · | · | · | · | · | $305.0K | |
| Total Assets | $1.26B | $1.04B | $641M | $363M | $273M | $287M | $442M | $485M | $192M | $41M | $363.6K | $101M | |
| Accounts Payable | $49M | $44M | $28M | $24M | $21M | $1M | $1M | $2M | $2M | $762.0K | $102.3K | $3M | |
| Accrued Liabilities | $260M | $125M | $90M | $91M | $55M | $45M | $24M | $6M | $8M | $4M | $70.2K | · | |
| Current Liabilities | $310M | $169M | $119M | $116M | $77M | $47M | $25M | $8M | $10M | $5M | $49M | $31M | |
| Capital Leases | $7M | $1M | $1M | $0 | $387.0K | $468.0K | $361.0K | · | · | · | · | $43.0K | |
| Total Liabilities | $657M | $288M | $235M | $165M | $77M | $47M | $25M | $8M | $10M | $5M | $49M | $36M | |
| Long-term Debt | $340M | $118M | $115M | $70M | · | · | · | · | · | · | · | · | |
| Total Debt | $340M | $118M | $115M | $49M | · | · | · | · | · | · | · | · | |
| Common Stock | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $1.0K | $1.0K | $18 | $11.0K | |
| Retained Earnings | $-2.09B | $-1.80B | $-1.34B | $-963M | $-667M | $-425M | $-223M | $-139M | $-106M | $-75M | $-49M | $-638M | |
| AOCI | $873.0K | $468.0K | $468.0K | $-32.0K | $-80.0K | $47.0K | $216.0K | $-319.0K | $-31.0K | $25.0K | $4.0K | $4.0K | |
| Stockholders' Equity | $603M | $754M | $405M | $197M | $196M | $240M | $417M | $477M | $182M | $36M | $-49M | $-42M | |
| Liabilities + Equity | $1.26B | $1.04B | $641M | $363M | $273M | $287M | $442M | $485M | $192M | $41M | $363.6K | $101M | |
| Shares Outstanding | 22,842,073 | 22,004,679 | 19,875,427 | 18,102,523 | 17,103,395 | 15,508,146 | 15,429,154 | 15,409,023 | 14,227,634 | 11,951,866 | 176,158 | 109,120,670 |
Flux de trésorerie 11
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $1M | $527.0K | $467.0K | $405.0K | $471.0K | $112.0K | $96.0K | $77.0K | $156 | $662.0K | $673.0K | |
| Stock-based Comp | $98M | $80M | $50M | $32M | $27M | $21M | $23M | $13M | $3M | $8M | $4M | $7M | |
| Other Non-cash | $-905.0K | $-71M | $-862.0K | $38M | $31M | $23M | $19M | · | $6M | · | · | · | |
| Operating Cash Flow | $-190M | $-456M | $-324M | $-225M | $-184M | $-158M | $-42M | $-26M | $-22M | $-18M | $-3M | $-79M | |
| CapEx | $467.0K | $1M | $1M | $217.0K | $209.0K | $334.0K | $172.0K | $22.0K | $125.0K | $3.0K | $58.0K | $144.0K | |
| Investing Cash Flow | $32M | $-274M | $-503M | $207M | $-5M | $160M | $31M | $-380M | $-22M | $22M | · | · | |
| Stock Issued | · | · | · | · | · | · | · | · | · | $6M | $6 | $90M | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $6M | · | $90M | |
| Financing Cash Flow | $256M | $735M | $595M | $313M | $171M | $5M | $235.0K | $314M | $174M | $14M | · | · | |
| Net Change in Cash | $99M | $5M | $-232M | $295M | $-18M | · | · | · | $129M | $19M | · | · | |
| Free Cash Flow | $-190M | $-457M | $-326M | $-225M | $-184M | $-158M | $-42M | · | $-22M | $-18M | · | $-79M |
Rentabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -31.3% | -276.4% | · | · | · | · | · | · | · | · | · | · | |
| Net Margin | -30.1% | -258.6% | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -31.2% | -275.8% | · | · | · | · | · | · | · | · | · | · | |
| ROA | -25.1% | -55.4% | -74.5% | -92.9% | -86.3% | -55.5% | -18.1% | · | -26.7% | · | · | · | |
| ROE | -44.4% | -60.8% | -174.8% | -283.9% | -112.2% | -76.4% | -19.6% | · | -28.5% | · | · | · |
Liquidité et Solvabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 4.0 | 6.1 | 5.4 | 3.1 | 3.5 | 6.1 | 17.5 | · | 19.1 | 8.6 | · | 3.2 | |
| Quick Ratio | 1.1 | 0.9 | 0.8 | 2.9 | 0.5 | 1.2 | 1.9 | · | 19.0 | 8.4 | · | 3.2 | |
| Debt / Equity | 0.6 | 0.2 | 0.3 | 0.2 | · | · | · | · | · | · | · | · | |
| LT Debt / Equity | 0.6 | 0.2 | 0.3 | 0.2 | · | · | · | · | · | · | · | · | |
| Interest Coverage | · | · | -29.9 | -74.1 | · | · | · | · | · | -20.8 | · | · |
Efficacité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.8 | 0.2 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | · | · | · | |
| Inventory Turnover | · | 0.4 | · | · | · | · | · | · | · | · | · | · | |
| Receivables Turnover | 10.2 | 6.7 | · | · | · | · | · | · | · | · | · | · |
Taux de croissance 1
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 432.1% | · | · | · | · | · | · | · | · | · | · | · |
Valorisation (TTM) 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $958M | $180M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | · | · | · | |
| Net Income TTM | $-288M | $-466M | $-374M | $-295M | $-242M | $-202M | $-84M | $-33M | $-31M | $-26M | · | · | |
| Market Cap | $13.30B | $6.79B | $4.60B | $5.25B | $1.45B | $1.72B | $1.41B | · | $1.31B | $178M | · | $10.12B | |
| Enterprise Value | $13.44B | $6.81B | $4.61B | $4.97B | · | · | · | · | · | · | · | · | |
| P/E | -45.3 | -14.1 | -11.6 | -16.8 | -5.8 | -8.5 | · | · | · | · | · | · | |
| P/S | 13.9 | 37.7 | · | · | · | · | · | · | · | · | · | · | |
| P/B | 22.1 | 9.0 | 11.3 | 26.6 | 7.4 | 7.2 | 3.4 | · | 7.2 | 4.9 | · | 155.4 | |
| P / Tangible Book | 22.3 | 9.1 | 11.3 | 26.6 | 7.4 | 7.2 | · | · | · | · | · | · | |
| P / Cash Flow | -70.2 | -14.9 | -14.2 | -23.4 | -7.9 | -10.9 | -33.8 | · | -58.5 | -10.1 | · | -128.2 | |
| P / FCF | -70.0 | -14.9 | -14.1 | -23.3 | -7.9 | -10.9 | -33.6 | · | -58.2 | -10.1 | · | -128.0 | |
| EV / EBITDA | -45.0 | -13.7 | -12.1 | -17.0 | · | · | · | · | · | · | · | · | |
| EV / FCF | -70.7 | -14.9 | -14.2 | -22.1 | · | · | · | · | · | · | · | · | |
| EV / Revenue | 14.0 | 37.8 | · | · | · | · | · | · | · | · | · | · | |
| Earnings Yield | -2.2% | -7.1% | -8.6% | -5.9% | -17.3% | -11.8% | · | · | · | · | · | · |
Compte de résultat 14
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $364M | $311M | $321M | $287M | $213M | $137M | $103M | $62M | $15M | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Cost of Revenue | · | · | · | · | · | $5M | · | · | · | $0 | · | · | · | · | · | · | |
| SG&A Expense | $289M | $269M | $240M | $209M | $197M | $168M | $141M | $108M | $105M | $81M | $47M | $28M | $18M | $16M | $15M | $12M | |
| Operating Expenses | $421M | $404M | $381M | $401M | $260M | $217M | $170M | $178M | $177M | $152M | $117M | $99M | $86M | $78M | $85M | $80M | |
| Operating Income | $-56M | $-93M | $-60M | $-114M | $-47M | $-79M | $-67M | $-116M | $-163M | $-152M | $-117M | $-99M | $-86M | $-78M | $-85M | $-80M | |
| Interest Expense | · | · | · | · | · | $3M | · | $4M | $4M | $4M | $4M | $4M | $3M | $2M | $2M | $2M | |
| Interest Income | $7M | $8M | $9M | $10M | $8M | $9M | $11M | $13M | $14M | $8M | $9M | $3M | $4M | $4M | $1M | $717.0K | |
| Other Non-op | $-795.0K | $-2M | $-128.0K | $-293.0K | $-42.0K | $0 | $0 | $0 | $0 | · | · | · | · | · | · | · | |
| Net Income | $-58M | $-94M | $-59M | $-114M | $-42M | $-73M | $-59M | $-107M | $-152M | $-148M | $-112M | $-99M | $-86M | $-77M | $-86M | $-81M | |
| EPS (Basic) | $-1.99 | $-3.25 | $-2.55 | $-4.01 | $-1.50 | $-2.61 | $-2.50 | $-4.92 | $-7.10 | $-7.38 | $-5.73 | $-5.34 | $-4.69 | $-4.23 | $-4.98 | $-4.75 | |
| EPS (Diluted) | $-1.99 | $-3.25 | $-2.55 | $-4.01 | $-1.50 | $-2.61 | $-2.50 | $-4.92 | $-7.10 | $-7.38 | $-5.73 | $-5.34 | $-4.69 | $-4.23 | $-4.98 | $-4.75 | |
| Shares (Basic) | 29,145,271 | 29,032,422 | -44,346,523 | 28,508,089 | 28,232,604 | 28,085,234 | -41,877,182 | 21,745,929 | 21,402,646 | 20,001,569 | -36,287,516 | 18,476,414 | 18,310,952 | 18,187,924 | -34,172,984 | 17,103,395 | |
| Shares (Diluted) | 29,145,271 | 29,032,422 | -44,346,523 | 28,508,089 | 28,232,604 | 28,085,234 | -41,877,182 | 21,745,929 | 21,402,646 | 20,001,569 | -36,287,516 | 18,476,414 | 18,310,952 | 18,187,924 | -34,172,984 | 17,103,395 | |
| EBITDA | $-56M | $-92M | · | $-114M | $-47M | $-79M | · | $-116M | $-163M | $-152M | · | $-99M | $-86M | $-78M | · | $-80M |
Bilan 22
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $293M | $227M | $199M | $296M | $186M | $184M | $100M | $233M | $495M | $623M | · | $62M | $77M | $113M | · | $59M | |
| Receivables | $192M | $187M | $134M | $113M | $79M | $61M | $54M | $30M | $7M | · | · | · | · | · | · | · | |
| Inventory | $99M | $112M | $75M | $69M | $63M | $55M | $34M | $9M | $7M | $854.0K | · | · | · | · | · | · | |
| Prepaid Expense | $69M | $65M | $48M | $49M | $59M | $23M | $14M | $21M | $15M | $14M | · | $3M | $3M | $2M | · | $4M | |
| Current Assets | $1.20B | $1.18B | $1.25B | $1.35B | $1.00B | $988M | $1.03B | $1.06B | $1.09B | $1.07B | · | $235M | $302M | $331M | · | $157M | |
| PP&E (Net) | $12M | $8M | $1M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | · | $659.0K | $455.0K | $512.0K | · | $701.0K | |
| Intangibles | $7M | $7M | $7M | $7M | $5M | $5M | $5M | $5M | $5M | $5M | · | · | · | · | · | · | |
| Other Non-current Assets | $21M | $23M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Total Assets | $1.24B | $1.23B | $1.26B | $1.36B | $1.02B | $997M | $1.04B | $1.07B | $1.10B | $1.08B | · | $238M | $302M | $332M | · | $159M | |
| Accounts Payable | $35M | $61M | $49M | $45M | $38M | $42M | $44M | $46M | $9M | $22M | · | $17M | $18M | $12M | · | $19M | |
| Accrued Liabilities | $339M | $276M | $260M | $345M | $157M | $124M | $125M | $131M | $116M | $92M | · | $83M | $82M | $86M | · | $80M | |
| Current Liabilities | $374M | $338M | $310M | $391M | $197M | $167M | $169M | $178M | $125M | $114M | · | $100M | $100M | $98M | · | $99M | |
| Capital Leases | $6M | $5M | $7M | $6M | $5M | $750.0K | $1M | $1M | $900.0K | $1M | · | $1M | · | · | · | $71.0K | |
| Total Liabilities | $721M | $684M | $657M | $737M | $319M | $286M | $288M | $296M | $243M | $232M | · | $216M | $199M | $182M | · | $148M | |
| Long-term Debt | $341M | $340M | $340M | $340M | $118M | $118M | · | $117M | $117M | $116M | · | $149M | $132M | $114M | · | $68M | |
| Total Debt | $341M | $340M | · | $340M | $118M | $118M | · | $117M | $117M | $116M | · | $115M | $99M | $84M | · | $49M | |
| Common Stock | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | · | $2.0K | $2.0K | $2.0K | · | $2.0K | |
| Retained Earnings | $-2.24B | $-2.18B | $-2.09B | $-2.03B | $-1.92B | $-1.88B | $-1.80B | $-1.74B | $-1.64B | $-1.48B | · | $-1.22B | $-1.13B | $-1.04B | · | $-877M | |
| AOCI | $808.0K | $1M | $873.0K | $1M | $1M | $389.0K | $468.0K | $1M | $-368.0K | $-172.0K | · | $-42.0K | $-89.0K | $-86.0K | · | $-237.0K | |
| Stockholders' Equity | $524M | $543M | $603M | $626M | $696M | $711M | $754M | $777M | $857M | $851M | $405M | $22M | $104M | $150M | $197M | $11M | |
| Liabilities + Equity | $1.24B | $1.23B | $1.26B | $1.36B | $1.02B | $997M | $1.04B | $1.07B | $1.10B | $1.08B | · | $238M | $302M | $332M | · | $159M | |
| Shares Outstanding | 23,093,974 | 23,041,918 | 22,842,073 | 22,704,303 | 22,221,116 | 22,187,716 | 22,004,679 | 21,806,436 | 19,875,427 | 19,875,427 | 19,875,427 | 18,494,192 | 18,459,033 | 18,283,074 | 18,102,523 | 17,103,395 |
Flux de trésorerie 9
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $381.0K | $386.0K | $392.0K | $358.0K | $377.0K | $379.0K | $363.0K | $298.0K | $267.0K | $168.0K | $142.0K | $135.0K | $126.0K | $124.0K | $129.0K | $121.0K | |
| Stock-based Comp | $35M | $34M | $26M | $26M | $25M | $21M | $18M | $18M | $24M | $20M | $15M | $13M | $11M | $11M | $8M | $8M | |
| Other Non-cash | · | $-107M | · | · | · | $-37M | · | · | · | $-22M | · | · | · | $-19M | · | · | |
| Operating Cash Flow | $23M | $-167M | $-133M | $80M | $-47M | $-89M | $-104M | $-67M | $-135M | $-149M | $-80M | $-85M | $-75M | $-84M | $-59M | $-59M | |
| CapEx | $4M | $4M | $-390.0K | $857.0K | $0 | $0 | $195.0K | $779.0K | $131.0K | $357.0K | $1M | $339.0K | $69.0K | $35.0K | $29.0K | $33.0K | |
| Investing Cash Flow | $34M | $192M | $28M | $-207M | $48M | $164M | $-48M | $-202M | $-122M | $98M | $-362M | $50M | $-4M | $-187M | $66M | $65M | |
| Financing Cash Flow | $3M | $2M | $9M | $237M | $2M | $9M | $20M | $7M | $134M | $574M | $480M | $20M | $43M | $53M | $264M | $0 | |
| Net Change in Cash | $61M | $28M | $-97M | $110M | $3M | $84M | $-133M | $-262M | $-123M | $523M | $38M | $-15M | $-36M | $-218M | · | · | |
| Free Cash Flow | · | $-171M | · | · | · | $-89M | · | · | · | $-150M | · | · | · | $-84M | · | · |
Rentabilité 5
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -15.5% | -29.8% | · | -39.7% | -22.2% | -57.8% | · | · | · | · | · | · | · | · | · | · | |
| Net Margin | -15.9% | -30.3% | · | -39.8% | -19.9% | -53.4% | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -15.5% | -29.7% | · | -39.7% | -22.2% | -57.5% | · | · | · | · | · | · | · | · | · | · | |
| ROA | -5.1% | -8.5% | · | -9.4% | -4.0% | -7.0% | · | -16.3% | -21.7% | -20.9% | · | -49.8% | -33.1% | -27.7% | · | -35.0% | |
| ROE | -9.5% | -15.0% | · | -16.3% | -5.4% | -9.4% | · | -26.8% | -31.6% | -29.5% | · | -599.9% | -91.7% | -52.0% | · | -66.1% |
Liquidité et Solvabilité 5
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.2 | 3.5 | · | 3.4 | 5.1 | 5.9 | · | 6.0 | 8.7 | 9.4 | · | 2.4 | 3.0 | 3.4 | · | 1.6 | |
| Quick Ratio | 1.3 | 1.2 | · | 1.0 | 1.4 | 1.5 | · | 1.5 | 4.0 | 5.4 | · | 0.6 | 0.8 | 1.2 | · | 0.6 | |
| Debt / Equity | 0.7 | 0.6 | · | 0.5 | 0.2 | 0.2 | · | 0.2 | 0.1 | 0.1 | · | 5.2 | 1.0 | 0.6 | · | 4.6 | |
| LT Debt / Equity | 0.7 | 0.6 | · | 0.5 | 0.2 | 0.2 | · | 0.2 | 0.1 | 0.1 | · | 5.2 | 1.0 | 0.6 | · | 4.6 | |
| Interest Coverage | · | · | · | · | · | -24.1 | · | -31.6 | -44.5 | -39.6 | · | -28.1 | -29.8 | -33.5 | · | -53.5 |
Efficacité 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.3 | 0.3 | · | 0.2 | 0.2 | 0.1 | · | · | · | 0.0 | · | · | · | · | · | · | |
| Inventory Turnover | · | · | · | · | · | 0.2 | · | · | · | · | · | · | · | · | · | · | |
| Receivables Turnover | 2.7 | 2.5 | · | 4.0 | 4.9 | 4.5 | · | · | · | · | · | · | · | · | · | · |
Valorisation (TTM) 14
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $1.18B | $949M | · | $699M | $427M | $214M | · | $77M | $15M | $0 | · | $0 | $0 | $0 | · | · | |
| Net Income TTM | $-309M | $-324M | · | $-337M | $-374M | $-480M | · | $-519M | $-510M | $-444M | · | $-347M | $-330M | $-315M | · | $-274M | |
| Market Cap | $12.40B | $12.06B | · | $10.41B | $6.72B | $7.35B | · | $4.63B | $5.57B | $5.31B | · | $2.70B | $4.26B | $4.43B | · | $1.11B | |
| Enterprise Value | $12.45B | $12.18B | · | $10.46B | $6.66B | $7.28B | · | $4.51B | $5.19B | $4.80B | · | $2.75B | $4.29B | $4.40B | · | $1.10B | |
| P/E | -49.9 | -46.0 | · | -30.1 | -17.6 | -14.6 | · | -8.5 | -11.0 | -11.6 | · | -7.6 | -12.4 | -13.4 | · | -4.1 | |
| P/S | 10.5 | 12.7 | · | 14.9 | 15.8 | 34.3 | · | 60.2 | 380.4 | · | · | · | · | · | · | · | |
| P/B | 23.7 | 22.2 | · | 16.6 | 9.7 | 10.3 | · | 6.0 | 6.5 | 6.2 | · | 121.4 | 41.2 | 29.5 | · | 104.2 | |
| P / Tangible Book | 24.0 | 22.5 | · | 16.8 | 9.7 | 10.4 | · | 6.0 | 6.5 | 6.3 | · | 121.4 | 41.2 | 29.5 | · | 104.2 | |
| P / Cash Flow | · | -72.0 | · | · | · | -82.7 | · | · | · | -35.6 | · | · | · | -52.7 | · | · | |
| P / FCF | · | -70.4 | · | · | · | -82.7 | · | · | · | -35.5 | · | · | · | -52.7 | · | · | |
| EV / EBITDA | -221.1 | -131.9 | · | -91.8 | -141.0 | -92.3 | · | -38.8 | -31.9 | -31.6 | · | -27.9 | -49.6 | -56.3 | · | -13.7 | |
| EV / FCF | · | -71.1 | · | · | · | -81.9 | · | · | · | -32.1 | · | · | · | -52.3 | · | · | |
| EV / Revenue | 10.6 | 12.8 | · | 15.0 | 15.6 | 34.0 | · | 58.7 | 354.6 | · | · | · | · | · | · | · | |
| Earnings Yield | -2.0% | -2.2% | · | -3.3% | -5.7% | -6.9% | · | -11.8% | -9.1% | -8.6% | · | -13.2% | -8.1% | -7.5% | · | -24.7% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $958M | $180M | $0 | $0 | $0 |
| Marge d'exploitation % | -31.3% | -276.4% | — | — | — |
| Résultat net | $-288M | $-466M | $-374M | $-295M | $-242M |
| BPA dilué | $-10.15 | $-17.31 | $-17.33 | $-17.23 | $-14.63 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Dette / Capitaux propres | 0.6 | 0.2 | 0.3 | 0.2 | — |
| Ratio de liquidité | 4.0 | 6.1 | 5.4 | 3.1 | 3.5 |
| Ratio de liquidité réduite | 1.1 | 0.9 | 0.8 | 2.9 | 0.5 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-190M | $-457M | $-326M | $-225M | $-184M |
Dernières actualités Actualités récentes mentionnant cette entreprise
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Détenteurs institutionnels (13F) 462 déclarants · $9.9B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 87 (+16 vs T. préc.) | 38 (-26 vs T. préc.) | 149 (+17 vs T. préc.) | 124 (-10 vs T. préc.) | +588K |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | $1 150 754 190 | 2 143 131 | 11,58% | Actions |
| RTW INVESTMENTS, LP | $1 070 510 235 | 1 993 687 | 10,77% | Actions |
| Avoro Capital Advisors LLC | $984 408 154 | 1 833 333 | 9,90% | Actions |
| PAULSON & CO. INC. | $719 523 739 | 1 340 020 | 7,24% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $448 711 933 | 835 668 | 4,51% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $419 750 461 | 781 731 | 4,22% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $412 459 753 | 768 153 | 4,15% | Actions |
| STATE STREET CORP | $282 995 975 | 527 057 | 2,85% | Actions |
| CITADEL ADVISORS LLC | $212 854 497 | 396 414 | 2,14% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $175 309 472 | 326 397 | 1,76% | Actions |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $174 037 845 | 324 123 | 1,75% | Actions |
| FMR LLC | $173 569 624 | 323 251 | 1,75% | Actions |
| Polar Capital Holdings Plc | $131 162 924 | 244 274 | 1,32% | Actions |
| NORGES BANK | $114 846 088 | 213 886 | 1,16% | Actions |
| Artisan Partners Limited Partnership | $112 869 575 | 210 205 | 1,14% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $112 652 110 | 209 800 | 1,13% | Option d'achat |
| AMERIPRISE FINANCIAL INC | $110 097 782 | 205 040 | 1,11% | Actions |
| Pictet Asset Management Holding SA | $103 486 147 | 192 896 | 1,04% | Actions |
| ALLIANCEBERNSTEIN L.P. | $99 175 579 | 189 458 | 1,00% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $98 966 865 | 184 313 | 1,00% | Actions |
| TORONTO DOMINION BANK | $97 419 912 | 181 432 | 0,98% | Actions |
| Rock Springs Capital Management LP | $93 965 713 | 174 999 | 0,95% | Actions |
| Hood River Capital Management LLC | $90 789 654 | 169 084 | 0,91% | Actions |
| Holocene Advisors, LP | $82 112 542 | 152 924 | 0,83% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $79 796 140 | 148 610 | 0,80% | Actions |
| Point72 Asset Management, L.P. | $73 577 722 | 137 029 | 0,74% | Actions |
| Woodline Partners LP | $67 601 468 | 125 899 | 0,68% | Actions |
| Assenagon Asset Management S.A. | $66 696 707 | 124 214 | 0,67% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $65 283 992 | 121 583 | 0,66% | Actions |
| GOLDMAN SACHS GROUP INC | $65 240 499 | 121 502 | 0,66% | Actions |
| Caption Management, LLC | $63 091 625 | 117 500 | 0,63% | Option d'achat |
| Clearbridge Investments, LLC | $58 701 796 | 109 325 | 0,59% | Actions |
| Erste Asset Management GmbH | $58 111 529 | 110 210 | 0,58% | Actions |
| D. E. Shaw & Co., Inc. | $57 829 515 | 107 700 | 0,58% | Option d'achat |
| JANE STREET GROUP, LLC | $55 950 190 | 104 200 | 0,56% | Option d'achat |
| ARMISTICE CAPITAL, LLC | $53 695 000 | 100 000 | 0,54% | Actions |
| AMERICAN CENTURY COMPANIES INC | $53 371 576 | 99 396 | 0,54% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $50 872 254 | 94 743 | 0,51% | Actions |
| CITADEL ADVISORS LLC | $50 473 300 | 94 000 | 0,51% | Option de vente |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $50 436 250 | 93 931 | 0,51% | Actions |
| 683 Capital Management, LLC | $48 325 500 | 90 000 | 0,49% | Option de vente |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $47 520 075 | 88 500 | 0,48% | Option de vente |
| CITADEL ADVISORS LLC | $46 660 955 | 86 900 | 0,47% | Option d'achat |
| JANE STREET GROUP, LLC | $45 434 561 | 84 616 | 0,46% | Actions |
| MILLENNIUM MANAGEMENT LLC | $43 598 192 | 81 196 | 0,44% | Actions |
| Balyasny Asset Management L.P. | $42 392 203 | 78 950 | 0,43% | Actions |
| Driehaus Capital Management LLC | $41 932 573 | 78 094 | 0,42% | Actions |
| Candriam S.C.A. | $38 688 112 | 72 121 | 0,39% | Actions |
| Tri Locum Partners LP | $36 659 187 | 68 273 | 0,37% | Actions |
| Caption Management, LLC | $35 277 615 | 65 700 | 0,35% | Option de vente |
| Vestal Point Capital, LP | $34 901 750 | 65 000 | 0,35% | Actions |
| JANE STREET GROUP, LLC | $31 733 745 | 59 100 | 0,32% | Option de vente |
| BNP PARIBAS FINANCIAL MARKETS | $31 142 026 | 57 998 | 0,31% | Actions |
| UBS Group AG | $28 840 658 | 53 712 | 0,29% | Actions |
| Jones Hill Capital LP | $28 214 038 | 52 545 | 0,28% | Actions |
| EULAV Asset Management | $27 921 400 | 52 000 | 0,28% | Actions |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $27 164 938 | 51 519 | 0,27% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $24 668 557 | 45 942 | 0,25% | Actions |
| Affinity Asset Advisors, LLC | $21 478 000 | 40 000 | 0,22% | Actions |
| BANK OF AMERICA CORP /DE/ | $19 392 486 | 36 116 | 0,20% | Actions |
| MILLENNIUM MANAGEMENT LLC | $19 330 200 | 36 000 | 0,19% | Option d'achat |
| SEGALL BRYANT & HAMILL, LLC | $17 420 806 | 32 444 | 0,18% | Actions |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $17 056 217 | 31 765 | 0,17% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $16 784 520 | 31 259 | 0,17% | Actions |
| BlackRock, Inc. | $16 705 588 | 31 112 | 0,17% | Actions |
| GROUPAMA ASSET MANAGMENT | $16 611 546 | 30 941 | 0,17% | Actions |
| Swiss National Bank | $16 076 283 | 29 940 | 0,16% | Actions |
| PFM Health Sciences, LP | $15 739 615 | 29 313 | 0,16% | Actions |
| CANADA PENSION PLAN INVESTMENT BOARD | $15 614 506 | 29 080 | 0,16% | Actions |
| GILDER GAGNON HOWE & CO LLC | $15 342 272 | 28 573 | 0,15% | Actions |
| Integral Health Asset Management, LLC | $13 423 750 | 25 000 | 0,14% | Actions |
| California Public Employees Retirement System | $13 035 535 | 24 277 | 0,13% | Actions |
| WCM INVESTMENT MANAGEMENT, LLC | $12 119 531 | 22 985 | 0,12% | Actions |
| Susquehanna Portfolio Strategies, LLC | $11 814 511 | 22 003 | 0,12% | Actions |
| D. E. Shaw & Co., Inc. | $11 803 772 | 21 983 | 0,12% | Actions |
| Tao Capital Management LP | $11 275 950 | 21 000 | 0,11% | Actions |
| HSBC HOLDINGS PLC | $10 831 355 | 20 172 | 0,11% | Actions |
| FIRST TRUST ADVISORS LP | $10 645 570 | 19 826 | 0,11% | Actions |
| D. E. Shaw & Co., Inc. | $10 470 525 | 19 500 | 0,11% | Option de vente |
| Weiss Asset Management LP | $10 376 559 | 19 325 | 0,10% | Actions |
| ArrowMark Colorado Holdings LLC | $10 000 157 | 18 624 | 0,10% | Actions |
| RHUMBLINE ADVISERS | $9 747 742 | 18 154 | 0,10% | Actions |
| CITIGROUP INC | $9 665 100 | 18 000 | 0,10% | Option d'achat |
| CITIGROUP INC | $9 665 100 | 18 000 | 0,10% | Option de vente |
| SPHERA FUNDS MANAGEMENT LTD. | $9 353 132 | 17 419 | 0,09% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $8 923 593 | 17 047 | 0,09% | Actions |
| WOLVERINE TRADING, LLC | $8 507 520 | 19 200 | 0,09% | Option d'achat |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $8 405 952 | 15 655 | 0,08% | Actions |
| Cubist Systematic Strategies, LLC | $8 204 782 | 17 889 | 0,08% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $8 163 788 | 15 204 | 0,08% | Actions |
| JANUS HENDERSON GROUP PLC | $8 049 398 | 15 377 | 0,08% | Actions |
| RAYMOND JAMES FINANCIAL INC | $7 976 929 | 14 856 | 0,08% | Actions |
| Cutter Capital Management, LP | $7 949 520 | 24 000 | 0,08% | Actions |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $7 658 518 | 14 263 | 0,08% | Actions |
| ENVESTNET ASSET MANAGEMENT INC | $7 658 427 | 14 263 | 0,08% | Actions |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $7 515 689 | 13 997 | 0,08% | Actions |
| Catalyst Funds Management Pty Ltd | $7 281 579 | 13 561 | 0,07% | Actions |
| ALKEON CAPITAL MANAGEMENT LLC | $7 048 006 | 13 126 | 0,07% | Actions |
| AXA Investment Managers S.A. | $6 896 412 | 15 036 | 0,07% | Actions |
| JOURNEY STRATEGIC WEALTH LLC | $6 710 885 | 12 820 | 0,07% | Actions |
Initiés de la société 46 initiés · 25 dirigeants · 22 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| William John Sibold | President and CEO | 17 juillet 2026 M | 209 329 | 0 | 10 | $-1 368 254 |
| Chen Schor | Former President and CEO | 22 juillet 2016 F | 37 178 | 0 | 0 | $0 |
| Anne Clem Whitaker | President and CEO | 2 mars 2015 A | 500 000 | 0 | 0 | $0 |
| Safi R Bahcall | President and CEO | 13 novembre 2013 P | 2 053 135 | 0 | 0 | $0 |
| Alex G. Howarth | Chief Financial Officer | 23 janvier 2024 A | 18 737 | 0 | 0 | $0 |
| Marc R Schneebaum | Chief Financial Officer | 22 février 2021 A | 41 668 | 0 | 0 | $0 |
| Keith S Ehrlich | VP, Fin. and Admin., CFO | 3 mars 2014 A | 17 573 | 0 | 0 | $0 |
| Sumant Ramachandra | President, R&D | 11 mars 2013 A | 75 000 | 0 | 0 | $0 |
| David Soergel | Chief Medical Officer | 1 juin 2026 S | 10 033 | 0 | 1 | $-516 561 |
| Carole Huntsman | Chief Commercial Officer | 21 novembre 2024 S | 10 785 | 0 | 0 | $0 |
| Shannon T Kelley | General Counsel | 15 août 2024 A | 7 982 | 0 | 0 | $0 |
| Robert E. Waltermire | Senior VP, Chief Pharma Dev. | 14 juin 2024 M | 5 500 | 0 | 0 | $0 |
| Brian Joseph Lynch | SVP and General Counsel | 23 janvier 2024 A | 17 691 | 0 | 0 | $0 |
| Remy Sukhija | Chief Commercial Officer | 16 janvier 2023 A | 15 001 | 0 | 0 | $0 |
| Wendy E Rieder | Former SVP, Gen. Counsel | 22 juillet 2016 F | 17 730 | 0 | 0 | $0 |
| Vojo Vukovic | SVP, Chief Medical Officer | 2 octobre 2015 A | 35 249 | 0 | 0 | $0 |
| Arthur Mcmahon | SVP, Human Resources | 2 mars 2015 A | — | 0 | 0 | $0 |
| Steven B Bernitz | SVP, Corporate Development | 18 décembre 2013 A | 25 000 | 0 | 0 | $0 |
| Amar Singh | Sr. VP, Chief Business Officer | 5 mars 2013 A | 21 031 | 0 | 0 | $0 |
| Keizo Koya | Sr. VP, Drug Development | 6 mars 2012 A | 12 999 | 0 | 0 | $0 |
| BAILEY MICHAEL P | Sr. VP, Chief Comm. Officer | 5 août 2010 S | 29 627 | 0 | 0 | $0 |
| Jeremy G Chadwick | Sr. VP, Pgm Mgmt and Clin Ops | 1 mars 2010 A | 23 761 | 0 | 0 | $0 |
| Eric W Jacobson | Sr. VP, Research and CMO | 13 avril 2009 A | 25 300 | 0 | 0 | $0 |
| James G Barsoum | Sr. VP, Research | 13 avril 2009 A | — | 0 | 0 | $0 |
| Martin D Williams | Sr. VP, Business Dev., CBO | 27 février 2008 A | 200 | 0 | 0 | $0 |
| REED JOHN C | Administrateur | 15 août 2026 A | 647 | 0 | 0 | $0 |
| Daniel J. Brennan | Administrateur | 17 juin 2026 A | 1 371 | 0 | 0 | $0 |
| James M Daly | Administrateur | 17 juin 2026 A | 3 081 | 0 | 0 | $0 |
| Richard S Levy | Administrateur | 17 juin 2026 A | 22 469 | 0 | 0 | $0 |
| Rebecca Taub, M.D. | Administrateur | 17 juin 2026 A | 452 667 | 0 | 0 | $0 |
| Jacqualyn A Fouse | Administrateur | 17 juin 2026 A | 1 551 | 0 | 0 | $0 |
| Kenneth Bate | Administrateur | 15 août 2025 M | 2 627 | 0 | 0 | $0 |
| Fred B Craves | Administrateur | 13 septembre 2024 G | 360 076 | 0 | 0 | $0 |
| Baker Bros. Advisors LP | Administrateur | 21 mars 2024 P | — | 0 | 0 | $0 |
| Keith R Gollust | Administrateur | 16 juin 2022 A | 1 539 169 | 0 | 0 | $0 |
| David V Milligan | Administrateur | 16 juin 2022 A | 20 000 | 0 | 0 | $0 |
| BAY CITY CAPITAL LLC | Administrateur | 11 juin 2018 S | 113 472 | 0 | 0 | $0 |
| Scott D Morenstein | Administrateur | 1 janvier 2016 A | 17 857 | 0 | 0 | $0 |
| Donald W Kufe | Administrateur | 1 juillet 2015 A | 25 748 | 0 | 0 | $0 |
| William S Reardon | Administrateur | 1 juillet 2015 A | 49 392 | 0 | 0 | $0 |
| Robert N Wilson | Administrateur | 1 juillet 2015 A | 760 936 | 0 | 0 | $0 |
| Lan Bo Chen | Administrateur | 6 août 2009 P | 620 035 | 0 | 0 | $0 |
| Judah Folkman | Administrateur | 30 juin 2007 A | 7 676 | 0 | 0 | $0 |
| Lin Huey Chen | Détenteur de 10% | 6 août 2009 P | 620 035 | 0 | 0 | $0 |
| Paul A Friedman, M.D. | — | 13 août 2025 M | 187 164 | 0 | 0 | $0 |
| Bruce Kovner | — | 8 décembre 2015 S | 340 970 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 10 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Rebecca Taub, M.D. ×2 dépôts | 12 décembre 2025 | 7,80% | Amendement | — | SEC |
| Paul A Friedman, M.D. | 12 décembre 2025 | 7,80% | Amendement | — | SEC |
| Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker, Felix J. Baker ×5 dépôts | 25 mars 2024 | — | Dépôt initial | Structure du capital | SEC |
| Fred B. Craves, Bay City Capital LLC, Bay City Capital Management IV LLC, Bay City Capital Fund IV, L.P. ×4 dépôts | 13 décembre 2023 | — | Dépôt initial | — | SEC |
| Bay City Capital LLC, Bay City Capital Management IV LLC, Bay City Capital Fund IV, L.P., Bay City Capital Fund IV Co-Investment Fund, L.P. ×2 dépôts | 13 décembre 2019 | — | Dépôt initial | — | SEC |
| Paul A. Friedman, M.D. | 17 octobre 2019 | — | Dépôt initial | Investissement passif | SEC |
| Caxton Corporation, Kovner 2012 Family Trust B, Kovner 2015-A Investment Trust, OB Select Opportunities, LLC, KFO HOLDINGS LLC, Kovner, Bruce ×6 dépôts | 1 août 2016 | — | Dépôt initial | Investissement passif | SEC |
| Madrigal Pharmaceuticals, Inc. | 28 avril 2016 | — | Dépôt initial | Fusions et acquisitions / vente | SEC |
| CxSynta LLC, Caxton Corporation, Kovner 2012 Family Trust B, Kovner 2015-A Investment Trust, OB Select Opportunities, LLC, Ben-Ur, David, Shteinbuk, Yuriy, Weisberg, Heath, KFO HOLDINGS LLC, Kovner, Bruce ×19 dépôts | 23 novembre 2015 | — | Dépôt initial | Campagne de conseil d'administration | SEC |
| Keith R. Gollust ×2 dépôts | 15 janvier 2010 | — | Dépôt initial | Investissement passif | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 71 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| JXX · Janus Detroit Street Trust | 4,21% | 2 950 NS | 30 avril 2026 | N-PORT |
| HRTS · Tema ETF Trust | 1,46% | 1 519 NS | 31 mai 2026 | N-PORT |
| BBP · ETFis Series Trust I | 1,44% | 1 655 NS | 30 avril 2026 | N-PORT |
| GURU · Global X Funds | 1,15% | 1 300 NS | 30 avril 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 1,12% | 11 249 NS | 30 avril 2026 | N-PORT |
| ILDR · First Trust Exchange-Traded Fund VI… | 1,10% | 6 360 NS | 31 mai 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 1,06% | 430 NS | 31 mai 2026 | N-PORT |
| MEDI · Harbor ETF Trust | 0,90% | 477 NS | 30 avril 2026 | N-PORT |
| BIB · ProShares Trust | 0,57% | 847 NS | 31 mai 2026 | N-PORT |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,52% | 5 239 NS | 30 avril 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,42% | 440 NS | 31 mai 2026 | N-PORT |
| ESSC · Strategy Shares | 0,36% | 178 NS | 30 avril 2026 | N-PORT |
| IQSM · New York Life Investments ETF Trust | 0,35% | 2 130 NS | 30 avril 2026 | N-PORT |
| RSSL · Global X Funds | 0,27% | 7 379 NS | 30 avril 2026 | N-PORT |
| ANEW · ProShares Trust | 0,25% | 39 NS | 31 mai 2026 | N-PORT |
| BKMC · BNY Mellon ETF Trust | 0,22% | 2 668 NS | 30 avril 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,22% | 3 320 NS | 31 mai 2026 | N-PORT |
| ITWO · ProShares Trust | 0,21% | 806 NS | 31 mai 2026 | N-PORT |
| FSMD · FIDELITY COVINGTON TRUST | 0,21% | 9 660 NS | 30 avril 2026 | N-PORT |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,20% | 5 201 NS | 30 avril 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,20% | 89 487 NS | 31 mai 2026 | N-PORT |
| BBMC · J.P. Morgan Exchange-Traded Fund Tr… | 0,19% | 7 425 NS | 30 avril 2026 | N-PORT |
| FSCC · Federated Hermes ETF Trust | 0,18% | 997 NS | 31 mai 2026 | N-PORT |
| SCHM · SCHWAB STRATEGIC TRUST | 0,17% | 50 311 NS | 31 mai 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,16% | 1 441 NS | 30 avril 2026 | N-PORT |
| UWM · ProShares Trust | 0,13% | 630 NS | 31 mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,12% | 6 819 NS | 30 avril 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,10% | 2 022 NS | 31 mai 2026 | N-PORT |
| ESUM · Strategy Shares | 0,10% | 296 NS | 30 avril 2026 | N-PORT |
| URTY · ProShares Trust | 0,09% | 635 NS | 31 mai 2026 | N-PORT |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,08% | 16 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,04% | 16 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,03% | 5 488 NS | 31 mai 2026 | N-PORT |
| TILT · FlexShares Trust | 0,02% | 810 NS | 30 avril 2026 | N-PORT |
| SCHK · SCHWAB STRATEGIC TRUST | 0,01% | 1 516 NS | 31 mai 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,01% | 11 079 NS | 31 mai 2026 | N-PORT |
| GUSA · Goldman Sachs ETF Trust II | 0,01% | 536 NS | 31 mai 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 161 NS | 30 avril 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 1 165 NS | 30 avril 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 463 NS | 30 avril 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,00% | 8 NS | 31 mai 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VB · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VBK · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTI · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | — | — | 30 juillet 2026 | Quotidien |
| VT · VANGUARD INTERNATIONAL EQUITY INDEX… | — | — | 15 juillet 2026 | Quotidien |
| VONE · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VONG · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |