XENE Xenon Pharmaceuticals Inc. - Common Shares
$63,95
Prix · Aoû 19, 2026
Données fondamentales au Aoû 6, 2026
Fourchette 52 semaines
$36–$73
76% of range
Note des analystes
BUY
26 analysts
Objectif de cours
$81
+27% upside
P/E (TTM)
-14.7
ROE
-56.9%
Marge nette
-4612.1%
À propos de Xenon Pharmaceuticals Inc. - Common Shares Présentation de l'entreprise depuis Wikipedia
XENE Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$63.95
Capitalisation Boursière
$5.12B
P/E (TTM)
-14.7
BPA (TTM)
$-4.36
Revenus (TTM)
$8M
Rendement div.
—
ROE
-56.9%
Dette/Capitaux propres
—
Fourchette 52 semaines
$36 – $73
XENE Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
$8M
2016-12-31
→
2025-12-31
BPA
$-4.36
2016-12-31
→
2025-12-31
Flux de trésorerie libre
$-280M
2016-12-31
→
2025-12-31
Marges
-4612.1%
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
XENE
Médiane des pairs
P/E (TTM)
-14.7
—
P/S (TTM)
682.2
418.4
P/B
8.8
2.3
Price / FCF (Cours / FCF)
-18.3
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
XENE
Médiane des pairs
Operating Margin (Marge d'exploitation)
-4974.3%
—
Net Profit Margin (Marge nette)
-4612.1%
-549.8%
ROA
-48.3%
-41.8%
ROE
-56.9%
-54.1%
ROIC
-64.3%
—
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
XENE
Médiane des pairs
Current Ratio (Ratio de liquidité)
13.4
12.6
Quick Ratio (Ratio de liquidité réduite)
13.1
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
XENE
Médiane des pairs
Revenue CAGR 3Y (CAGR du chiffre d'affaires 3 ans)
-7.4%
—
Revenue CAGR 5Y (CAGR du chiffre d'affaires 5 ans)
-25.3%
—
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
XENE
Médiane des pairs
XENE Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
26 analystes
- Achat fort 11 42,3%
- Achat 14 53,8%
- Conserver 1 3,8%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
19 analystes · 2026-08-16
Médiane
$80.00
← En dessous de tous les objectifs
$63.95
Bas
$69.00
Haut
$100.00
Objectif médian
$80.00
+25,1%
Objectif moyen
$81.30
+27,1%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
0.01%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-1.11 | $-1.16 | 0.05% |
| 31 mars 2026 | $-1.17 | $-1.21 | 0.04% |
| 31 décembre 2025 | $-1.31 | $-1.22 | -0.09% |
| 30 septembre 2025 | $-1.15 | $-1.18 | 0.03% |
| 30 juin 2025 | $-1.07 | $-1.01 | -0.06% |
| 31 mars 2025 | $-0.83 | $-0.93 | 0.10% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| XENE | $3.59B | -10.3 | — | -4612.1% | -56.9% | — |
| AUPH | $2.11B | 7.7 | 20.4% | 101.5% | 62.7% | — |
| ABUS | $926M | -28.3 | 128.2% | -237.9% | -42.0% | — |
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| ACOG | $141M | -5.5 | — | -202.2% | -43.8% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 16
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $8M | $0 | $0 | $9M | $18M | $32M | $7M | · | $311.0K | $2M | $16M | $28M | |
| R&D Expense | $301M | $210M | $168M | $106M | $75M | $51M | $39M | $24M | $26M | $20M | $15M | $12M | |
| SG&A Expense | $80M | $69M | $47M | $33M | $22M | $13M | $11M | $8M | $7M | $7M | $10M | $5M | |
| Operating Expenses | $381M | $279M | $214M | $139M | $97M | $63M | $50M | $38M | $33M | $27M | $25M | $17M | |
| Operating Income | $-373M | $-279M | $-214M | $-129M | $-79M | $-31M | $-43M | $-38M | $-33M | $-25M | $-9M | $11M | |
| Interest Expense | · | · | · | · | · | $484.0K | $1M | $1M | · | · | · | · | |
| Interest Income | $27M | $42M | $28M | $9M | $466.0K | $2M | $2M | $1M | $477.0K | $504.0K | $542.0K | $568.0K | |
| Other Non-op | $28M | $41M | $31M | $4M | $105.0K | $2M | · | · | · | · | · | · | |
| Pretax Income | $-345M | $-238M | $-183M | $-125M | $-79M | $-29M | $-42M | $-35M | · | · | · | · | |
| Income Tax | $1M | $-4M | $-292.0K | $118.0K | $-6.0K | $-257.0K | $-23.0K | $-24.0K | · | · | · | $0 | |
| Net Income | $-346M | $-234M | $-182M | $-125M | $-79M | $-29M | $-42M | $-34M | $-31M | $-23M | $-16M | $13M | |
| EPS (Basic) | $-4.36 | $-3.01 | $-2.73 | $-2.06 | $-1.77 | $-0.81 | · | $-1.63 | $-1.71 | $-1.48 | $-1.10 | $4.11 | |
| EPS (Diluted) | $-4.36 | $-3.01 | $-2.73 | $-2.06 | $-1.77 | $-0.81 | · | $-1.63 | $-1.72 | $-1.48 | $-1.10 | $3.28 | |
| Shares (Basic) | 79,253,751 | 77,894,643 | 66,889,005 | 60,542,142 | 43,627,452 | 34,542,213 | · | 19,425,711 | 17,985,061 | 15,493,474 | 14,281,837 | 3,165,572 | |
| Shares (Diluted) | 79,253,751 | 77,894,643 | 66,889,005 | 60,542,142 | 43,627,452 | 34,542,213 | · | 19,425,711 | 18,001,759 | 15,493,474 | 14,281,837 | 3,963,797 | |
| EBITDA | $-373M | $-279M | $-214M | $-129M | $-79M | $-31M | $-43M | $-38M | $-33M | $-25M | $-9M | $12M |
Bilan 23
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $199M | $143M | $149M | $57M | $176M | $45M | $25M | $68M | $20M | $17M | $59M | $72M | |
| Short-term Investments | $350M | $484M | $489M | $535M | $376M | $132M | $117M | $52M | $23M | $47M | · | $12M | |
| Receivables | · | $1M | $874.0K | $986.0K | $3M | $2M | $813.0K | $151.0K | $438.0K | $200.0K | $315.0K | $215.0K | |
| Prepaid Expense | $10M | $7M | $6M | $7M | $4M | $3M | $3M | $2M | $716.0K | $1M | $2M | $686.0K | |
| Current Assets | $561M | $635M | $645M | $600M | $559M | $182M | $145M | $121M | $45M | $66M | $61M | $85M | |
| PP&E (Net) | $9M | $10M | $10M | $6M | $4M | $4M | $2M | $991.0K | $1M | $1M | $2M | $2M | |
| Accum. Depreciation | $15M | $13M | $11M | $9M | $13M | $15M | $15M | $16M | $16M | $15M | $15M | $14M | |
| Total Assets | $633M | $798M | $965M | $754M | $572M | $189M | $148M | $122M | $46M | $67M | $64M | $87M | |
| Accounts Payable | $40M | $34M | $26M | $22M | $14M | $11M | $9M | $4M | $3M | $4M | $3M | $3M | |
| Accrued Liabilities | $36M | · | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $42M | $36M | $27M | $23M | $14M | $15M | $43M | $4M | $4M | $4M | $3M | $14M | |
| Capital Leases | $6M | $8M | $10M | $10M | $8M | $3M | $743.0K | · | · | · | · | · | |
| Other Non-current Liabilities | $3M | $0 | · | · | · | · | · | · | · | · | · | · | |
| Total Liabilities | $51M | $43M | $37M | $33M | $22M | $18M | $56M | $19M | $10M | $4M | $3M | $15M | |
| Long-term Debt | · | · | · | · | · | · | $16M | · | $7M | · | · | · | |
| Total Debt | · | · | · | · | · | · | $16M | $15M | $7M | · | · | · | |
| Common Stock | $1.60B | $1.46B | $1.44B | $1.07B | $783M | $398M | $294M | $266M | $174M | $173M | $149M | $147M | |
| Paid-in Capital | · | · | · | · | · | · | · | · | · | · | · | $30M | |
| Retained Earnings | $-1.25B | $-899M | $-665M | $-483M | $-357M | $-278M | $-250M | $-208M | $-173M | $-143M | $-120M | $-104M | |
| AOCI | $335.0K | $-2M | $-77.0K | $-3M | $-990.0K | $-990.0K | $-990.0K | $-990.0K | $-990.0K | $-990.0K | $-990.0K | $-990.0K | |
| Stockholders' Equity | $582M | $755M | $928M | $721M | $550M | $171M | $92M | $103M | $36M | $64M | $61M | $73M | |
| Liabilities + Equity | $633M | $798M | $965M | $754M | $572M | $189M | $148M | $122M | $46M | $67M | $64M | $87M | |
| Shares Outstanding | 80,010,790 | 76,416,086 | 75,370,977 | 62,587,701 | 51,634,752 | 35,012,125 | 28,139,228 | 25,750,721 | 17,998,420 | 17,930,590 | 14,385,336 | 14,181,333 |
Flux de trésorerie 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $3M | $3M | $2M | $1M | $906.0K | $644.0K | $429.0K | $586.0K | $649.0K | $864.0K | $1M | $738.0K | |
| Stock-based Comp | $54M | $51M | $32M | $20M | $10M | $6M | $3M | $3M | $2M | $2M | $4M | $760.0K | |
| Deferred Tax | $-3M | $-9M | $-292.0K | $-44.0K | $58.0K | $-285.0K | $-133.0K | $-105.0K | · | · | · | · | |
| Other Non-cash | · | · | · | · | · | · | · | · | · | · | · | $-14M | |
| Operating Cash Flow | $-279M | $-181M | $-151M | $-101M | $-70M | $-48M | $-5M | $-35M | $-29M | $-20M | $-18M | $266.0K | |
| CapEx | $799.0K | $3M | $6M | $3M | $2M | $3M | $1M | $507.0K | $315.0K | $279.0K | $551.0K | $2M | |
| Investing Cash Flow | $218M | $165M | $-111M | $-293M | $-247M | $-17M | $-66M | $-29M | $24M | · | · | · | |
| Stock Issued | · | · | · | · | · | $102M | $27M | $103M | · | $24M | $278.0K | $43M | |
| Net Stock Activity | · | · | · | · | · | $102M | $27M | $103M | · | $24M | $278.0K | $43M | |
| Financing Cash Flow | $117M | $12M | $354M | $278M | $448M | $86M | $28M | $112M | $7M | · | · | · | |
| Net Change in Cash | $56M | $-6M | $91M | $-118M | $131M | $20M | $-43M | $47M | $3M | $-42M | $-13M | $34M | |
| Taxes Paid | $8M | · | · | · | · | · | · | · | · | · | · | · | |
| Free Cash Flow | $-280M | $-184M | $-151M | $-101M | $-72M | $-51M | $-6M | $-35M | $-29M | $-20M | $-19M | $-1M | |
| Levered FCF | · | · | · | · | · | $-51M | $-7M | · | · | · | · | · |
Rentabilité 7
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -4974.3% | · | · | -1368.9% | -428.5% | -97.3% | -627.0% | · | -10474.3% | -1376.4% | -60.1% | 39.1% | |
| Net Margin | -4612.1% | · | · | -1329.0% | -427.9% | -89.6% | -609.1% | · | -9872.7% | -1275.5% | -101.1% | 45.9% | |
| Pretax Margin | -4598.6% | · | · | -1327.7% | -427.9% | -90.5% | -609.4% | · | · | · | · | · | |
| EBITDA Margin | -4974.3% | · | · | -1368.9% | -428.5% | -97.3% | -627.0% | · | -10474.3% | -1376.4% | -60.1% | 41.8% | |
| ROA | -48.3% | -26.6% | -21.2% | -18.9% | -20.7% | -17.1% | -30.8% | -40.9% | -54.0% | -35.0% | -20.8% | 18.4% | |
| ROE | -56.9% | -30.2% | -23.3% | -17.0% | -19.8% | -16.3% | -50.0% | -32.2% | -61.5% | -36.8% | -23.5% | -465.5% | |
| ROIC | -64.3% | -36.4% | -23.0% | -17.9% | -14.4% | -18.1% | -39.8% | · | · | · | · | · |
Liquidité et Solvabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 13.4 | 17.8 | 23.6 | 26.4 | 39.0 | 12.3 | 3.3 | 29.5 | 11.0 | 18.7 | 21.9 | 5.9 | |
| Quick Ratio | 13.1 | 17.7 | 23.4 | 26.1 | 38.7 | 12.1 | 3.3 | 29.0 | 10.8 | 18.3 | 21.2 | 5.9 | |
| Debt / Equity | · | · | · | · | · | · | 0.2 | 0.1 | 0.2 | · | · | · | |
| LT Debt / Equity | · | · | · | · | · | · | 0.1 | 0.1 | 0.2 | · | · | · | |
| Interest Coverage | · | · | · | · | · | -64.7 | -29.9 | -27.3 | · | · | · | · |
Efficacité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | 0.0 | 0.0 | 0.2 | 0.1 | · | 0.0 | 0.0 | 0.2 | 0.4 | |
| Receivables Turnover | · | · | · | 5.0 | 8.0 | 24.4 | 14.2 | · | 1.0 | 7.0 | 58.8 | 86.6 |
Taux de croissance 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | · | -48.8% | -42.7% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -7.4% | · | · | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | -25.3% | · | · | · | · | · | · | · | · | · | · | · |
Valorisation (TTM) 14
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $8M | $0 | $0 | $9M | $18M | $32M | $7M | $311.0K | $311.0K | $2M | $16M | $28M | |
| Net Income TTM | $-346M | $-234M | $-182M | $-125M | $-79M | $-29M | $-42M | $-34M | $-31M | $-23M | $-16M | $13M | |
| Market Cap | $3.59B | $3.00B | $3.47B | $2.47B | $1.61B | $538M | $369M | $162M | $51M | $138M | $116M | $280M | |
| Enterprise Value | · | · | · | · | · | · | $243M | $58M | $14M | · | · | · | |
| P/E | -10.3 | -13.0 | -16.9 | -19.1 | -17.6 | -19.0 | -7.0 | -3.9 | -1.6 | -5.2 | -7.3 | 6.0 | |
| P/S | 478.1 | · | · | 261.6 | 87.5 | 16.7 | 54.0 | 522.5 | 163.5 | 76.6 | 7.4 | 9.9 | |
| P/B | 6.2 | 4.0 | 3.7 | 3.4 | 2.9 | 3.1 | 4.0 | 1.6 | 1.4 | 2.2 | 1.9 | 3.8 | |
| P / Tangible Book | 6.2 | 4.0 | 3.7 | 3.4 | 2.9 | 3.1 | · | · | · | · | · | · | |
| P / Cash Flow | -12.8 | -16.5 | -23.9 | -25.1 | -23.2 | -11.2 | -79.6 | -4.7 | -1.8 | -7.1 | -6.4 | 1052.9 | |
| P / FCF | -12.8 | -16.2 | -23.0 | -24.4 | -22.5 | -10.6 | -62.8 | -4.6 | -1.8 | -7.0 | -6.2 | -221.8 | |
| EV / EBITDA | · | · | · | · | · | · | -5.7 | -1.5 | -0.4 | · | · | · | |
| EV / FCF | · | · | · | · | · | · | -41.4 | -1.7 | -0.5 | · | · | · | |
| EV / Revenue | · | · | · | · | · | · | 35.6 | 187.1 | 45.0 | · | · | · | |
| Earnings Yield | -9.7% | -7.7% | -5.9% | -5.2% | -5.7% | -5.3% | -14.3% | -25.8% | -60.9% | -19.2% | -13.7% | 16.6% |
Compte de résultat 15
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $0 | $0 | $8M | $0 | $0 | $0 | $0 | · | · | · | · | $0 | $132.0K | |
| R&D Expense | $99M | $89M | $88M | $77M | $75M | $61M | $59M | $57M | $50M | $44M | $41M | $43M | $44M | $40M | $35M | $29M | |
| SG&A Expense | $24M | $24M | $22M | $19M | $19M | $19M | $18M | $17M | $19M | $15M | $13M | $13M | $12M | $10M | $9M | $9M | |
| Operating Expenses | $123M | $112M | $110M | $96M | $94M | $80M | $77M | $74M | $69M | $59M | $54M | $56M | $56M | $49M | $43M | $38M | |
| Operating Income | $-123M | $-112M | $-110M | $-96M | $-94M | $-73M | $-77M | $-74M | $-69M | $-59M | $-54M | $-56M | $-56M | $-49M | $-43M | $-38M | |
| Interest Income | $12M | $7M | $5M | $6M | $7M | $8M | $9M | $10M | $11M | $11M | $9M | $7M | $7M | $5M | $4M | $3M | |
| Other Non-op | $12M | $7M | $5M | $6M | $9M | $8M | $8M | $11M | $11M | $12M | $9M | $7M | $8M | $8M | $7M | $391.0K | |
| Pretax Income | $-111M | $-105M | $-105M | $-90M | $-85M | $-65M | $-70M | $-63M | $-58M | $-48M | $-45M | $-49M | $-48M | $-41M | $-36M | $-38M | |
| Income Tax | $-585.0K | $-3M | $538.0K | $677.0K | $-626.0K | $427.0K | $-4M | $-320.0K | $-333.0K | $412.0K | $-205.0K | $-157.0K | $-220.0K | $290.0K | $1M | $-587.0K | |
| Net Income | $-111M | $-102M | $-105M | $-91M | $-85M | $-65M | $-66M | $-63M | $-58M | $-48M | $-45M | $-48M | $-47M | $-42M | $-37M | $-37M | |
| EPS (Basic) | $-1.11 | $-1.17 | $-1.31 | $-1.15 | $-1.07 | $-0.83 | $-0.83 | $-0.81 | $-0.75 | $-0.62 | $-0.65 | $-0.73 | $-0.72 | $-0.63 | $-0.59 | $-0.57 | |
| EPS (Diluted) | $-1.11 | $-1.17 | $-1.31 | $-1.15 | $-1.07 | $-0.83 | $-0.83 | $-0.81 | $-0.75 | $-0.62 | $-0.65 | $-0.73 | $-0.72 | $-0.63 | $-0.59 | $-0.57 | |
| Shares (Basic) | 99,609,804 | 87,345,717 | -157,635,173 | 79,247,976 | 78,953,445 | 78,687,503 | -155,297,289 | 77,926,205 | 77,671,128 | 77,594,599 | -130,698,977 | 66,002,163 | 65,861,138 | 65,724,681 | -115,968,641 | 65,465,069 | |
| Shares (Diluted) | 99,609,804 | 87,345,717 | -157,635,173 | 79,247,976 | 78,953,445 | 78,687,503 | -155,297,289 | 77,926,205 | 77,671,128 | 77,594,599 | -130,698,977 | 66,002,163 | 65,861,138 | 65,724,681 | -115,968,641 | 65,465,069 | |
| EBITDA | $-123M | $-112M | · | $-96M | $-94M | $-73M | · | $-74M | $-69M | $-59M | · | $-56M | $-56M | $-49M | · | $-38M |
Bilan 20
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $120M | $546M | $199M | $105M | $135M | $117M | $143M | $88M | $137M | $59M | · | $100M | $65M | $70M | · | $103M | |
| Short-term Investments | $811M | $549M | $350M | $358M | $352M | $433M | $484M | $566M | $585M | $641M | · | $427M | $475M | $458M | · | $535M | |
| Receivables | · | · | · | · | · | · | · | $938.0K | $853.0K | $833.0K | · | $805.0K | $2M | $2M | · | $2M | |
| Prepaid Expense | $14M | $11M | $10M | $17M | $12M | $7M | $7M | $5M | $6M | $7M | · | $4M | $3M | $4M | · | $9M | |
| Current Assets | $946M | $1.11B | $561M | $480M | $500M | $566M | $635M | $660M | $728M | $707M | · | $531M | $545M | $533M | · | $649M | |
| PP&E (Net) | $8M | $8M | $9M | $9M | $9M | $10M | $10M | $10M | $10M | $9M | · | $10M | $10M | $8M | · | $5M | |
| Accum. Depreciation | · | · | $15M | · | · | · | $13M | · | · | · | · | · | · | · | · | · | |
| Total Assets | $1.30B | $1.39B | $633M | $608M | $674M | $743M | $798M | $836M | $884M | $919M | · | $671M | $685M | $720M | · | $776M | |
| Accounts Payable | $44M | $38M | $40M | $37M | $32M | $31M | $34M | $28M | $30M | $21M | · | $23M | $27M | $21M | · | $16M | |
| Accrued Liabilities | $41M | $33M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $45M | $40M | $42M | $38M | $33M | $32M | $36M | $30M | $31M | $22M | · | $25M | $28M | $22M | · | $16M | |
| Capital Leases | $5M | $6M | $6M | $7M | $7M | $7M | $8M | $8M | $9M | $9M | · | $10M | $10M | $10M | · | $7M | |
| Other Non-current Liabilities | $3M | $3M | $3M | $3M | · | · | $0 | · | · | · | · | · | · | · | · | · | |
| Total Liabilities | $53M | $49M | $51M | $48M | $40M | $39M | $43M | $38M | $40M | $31M | · | $35M | $38M | $33M | · | $23M | |
| Common Stock | $2.43B | $2.42B | $1.60B | $1.48B | $1.47B | $1.46B | $1.46B | $1.44B | $1.44B | $1.44B | · | $1.12B | $1.08B | $1.07B | · | $1.06B | |
| Retained Earnings | $-1.46B | $-1.35B | $-1.25B | $-1.14B | $-1.05B | $-965M | $-899M | $-834M | $-771M | $-713M | · | $-620M | $-572M | $-524M | · | $-445M | |
| AOCI | $-3M | $-1M | $335.0K | $477.0K | $113.0K | $-836.0K | $-2M | $1M | $-2M | $-2M | · | $-3M | $-3M | $-2M | · | $-3M | |
| Stockholders' Equity | $1.24B | $1.34B | $582M | $560M | $634M | $704M | $755M | $798M | $844M | $888M | $928M | $637M | $646M | $687M | $721M | $753M | |
| Liabilities + Equity | $1.30B | $1.39B | $633M | $608M | $674M | $743M | $798M | $836M | $884M | $919M | · | $671M | $685M | $720M | · | $776M | |
| Shares Outstanding | 96,752,884 | 96,624,123 | 80,010,790 | 77,120,168 | 76,939,811 | 76,586,359 | 76,416,086 | 75,794,409 | 75,667,550 | 75,459,681 | · | 65,002,249 | 63,718,350 | 63,107,020 | · | 62,542,542 |
Flux de trésorerie 9
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $558.0K | $587.0K | $611.0K | $641.0K | $632.0K | $659.0K | $666.0K | $636.0K | $628.0K | $586.0K | $-629.0K | $2M | $602.0K | $354.0K | $296.0K | $358.0K | |
| Stock-based Comp | $17M | $17M | $14M | $14M | $14M | $12M | $14M | $13M | $15M | $9M | $9M | $9M | $8M | $6M | $6M | $6M | |
| Deferred Tax | $-2M | $447.0K | $-1M | $-701.0K | $-170.0K | $-1M | $-9M | $-322.0K | $-333.0K | $403.0K | $-200.0K | $-156.0K | $-224.0K | $288.0K | $5.0K | $-203.0K | |
| Operating Cash Flow | $-95M | $-89M | $-81M | $-72M | $-64M | $-62M | $-54M | $-51M | $-34M | $-46M | $-35M | $-48M | $-33M | $-34M | $-35M | $-30M | |
| CapEx | $275.0K | $133.0K | $318.0K | $281.0K | $157.0K | $43.0K | $783.0K | $590.0K | $2M | $188.0K | $78.0K | $1M | $2M | $2M | $2M | $386.0K | |
| Investing Cash Flow | $-331M | $-407M | $63M | $39M | $82M | $35M | $99M | $2M | $112M | $-43M | $-240M | $54M | $28M | $47M | $-12M | $-234M | |
| Financing Cash Flow | $26.0K | $843M | $114M | $2M | $65.0K | $1M | $12M | $0 | $0 | $0 | $324M | · | · | · | $6.0K | $699.0K | |
| Net Change in Cash | $-426M | $347M | $95M | $-31M | $19M | $-26M | $55M | $-49M | $78M | $-90M | $49M | $35M | $-5M | $12M | $-46M | $-266M | |
| Free Cash Flow | · | $-89M | · | · | · | $-62M | · | · | · | $-43M | · | · | · | $-37M | · | · |
Rentabilité 7
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | -969.8% | · | · | · | · | · | · | · | · | · | -28884.8% | |
| Net Margin | · | · | · | · | · | -867.3% | · | · | · | · | · | · | · | · | · | -28143.9% | |
| Pretax Margin | · | · | · | · | · | -861.6% | · | · | · | · | · | · | · | · | · | -28588.6% | |
| EBITDA Margin | · | · | · | · | · | -969.8% | · | · | · | · | · | · | · | · | · | -28884.8% | |
| ROA | -11.2% | -9.6% | · | -12.6% | -10.9% | -7.8% | · | -8.3% | -7.4% | -5.9% | · | -6.7% | -6.4% | -6.5% | · | -7.1% | |
| ROE | -11.8% | -10.0% | · | -13.4% | -11.5% | -8.2% | · | -8.8% | -7.8% | -6.1% | · | -7.0% | -6.6% | -6.8% | · | -7.4% | |
| ROIC | -9.9% | -8.2% | · | -17.3% | -14.8% | -10.4% | · | -9.2% | -8.1% | -6.7% | · | -8.7% | -8.6% | -7.2% | · | -5.0% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 21.0 | 27.8 | · | 12.5 | 15.1 | 17.7 | · | 22.2 | 23.3 | 31.8 | · | 21.5 | 19.3 | 23.7 | · | 41.8 | |
| Quick Ratio | 20.7 | 27.5 | · | 12.1 | 14.8 | 17.2 | · | 22.1 | 23.1 | 31.5 | · | 21.3 | 19.2 | 23.5 | · | 41.2 |
Efficacité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | · | · | · | · | · | · | · | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.0 |
Valorisation (TTM) 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $8M | · | $8M | $8M | $8M | · | · | · | · | · | $18M | $18M | $18M | · | $18M | |
| Net Income TTM | $-389M | $-343M | · | $-303M | $-270M | $-234M | · | $-217M | $-202M | $-186M | · | $-175M | $-157M | $-130M | · | $-103M | |
| Market Cap | $5.84B | $5.62B | · | $3.10B | $2.41B | $2.57B | · | $2.98B | $2.95B | $3.25B | · | $2.22B | $2.45B | $2.26B | · | $2.26B | |
| P/E | -13.4 | -13.8 | · | -10.4 | -9.0 | -11.1 | · | -13.5 | -13.8 | -15.9 | · | -12.9 | -15.6 | -17.0 | · | -19.7 | |
| P/S | · | 749.2 | · | 412.9 | 321.1 | 342.6 | · | · | · | · | · | 126.5 | 139.7 | 128.6 | · | 128.6 | |
| P/B | 4.7 | 4.2 | · | 5.5 | 3.8 | 3.6 | · | 3.7 | 3.5 | 3.7 | · | 3.5 | 3.8 | 3.3 | · | 3.0 | |
| P / Tangible Book | 4.7 | 4.2 | · | 5.5 | 3.8 | 3.6 | · | 3.7 | 3.5 | 3.7 | · | 3.5 | 3.8 | 3.3 | · | 3.0 | |
| P / Cash Flow | · | -63.2 | · | · | · | -41.7 | · | · | · | -75.2 | · | · | · | -65.6 | · | · | |
| P / FCF | · | -63.1 | · | · | · | -41.6 | · | · | · | -74.9 | · | · | · | -61.7 | · | · | |
| Earnings Yield | -7.5% | -7.3% | · | -9.6% | -11.1% | -9.0% | · | -7.4% | -7.2% | -6.3% | · | -7.8% | -6.4% | -5.9% | · | -5.1% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $8M | $0 | $0 | $9M | $18M |
| Marge d'exploitation % | -4974.3% | — | — | -1368.9% | -428.5% |
| Résultat net | $-346M | $-234M | $-182M | $-125M | $-79M |
| BPA dilué | $-4.36 | $-3.01 | $-2.73 | $-2.06 | $-1.77 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 13.4 | 17.8 | 23.6 | 26.4 | 39.0 |
| Ratio de liquidité réduite | 13.1 | 17.7 | 23.4 | 26.1 | 38.7 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-280M | $-184M | $-151M | $-101M | $-72M |
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Détenteurs institutionnels (13F) 334 déclarants · $4.2B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 58 (-17 vs T. préc.) | 22 (-10 vs T. préc.) | 113 (-7 vs T. préc.) | 87 (+22 vs T. préc.) | -3.8M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $413 296 388 | 6 847 190 | 9,78% | Actions |
| Avoro Capital Advisors LLC | $348 746 620 | 5 777 777 | 8,25% | Actions |
| Polar Capital Holdings Plc | $275 878 760 | 4 570 556 | 6,53% | Actions |
| Driehaus Capital Management LLC | $266 704 101 | 4 418 557 | 6,31% | Actions |
| Capital International Investors | $142 548 530 | 2 361 639 | 3,37% | Actions |
| STATE STREET CORP | $118 885 244 | 1 969 629 | 2,81% | Actions |
| TWO SIGMA INVESTMENTS, LP | $99 162 305 | 1 642 848 | 2,35% | Actions |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $97 523 411 | 1 615 696 | 2,31% | Actions |
| Affinity Asset Advisors, LLC | $96 274 200 | 1 595 000 | 2,28% | Actions |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $90 980 266 | 1 507 294 | 2,15% | Actions |
| ALLIANCEBERNSTEIN L.P. | $90 846 349 | 1 562 276 | 2,15% | Actions |
| Siren, L.L.C. | $79 588 523 | 1 318 564 | 1,88% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $74 162 795 | 1 228 797 | 1,75% | Actions |
| Pictet Asset Management Holding SA | $71 645 411 | 1 187 723 | 1,70% | Actions |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $69 677 471 | 1 154 365 | 1,65% | Actions |
| BRAIDWELL LP | $68 294 443 | 1 131 452 | 1,62% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $61 270 953 | 1 015 092 | 1,45% | Actions |
| CITADEL ADVISORS LLC | $60 749 141 | 1 006 447 | 1,44% | Actions |
| ORBIMED ADVISORS LLC | $53 869 550 | 892 471 | 1,27% | Actions |
| Caligan Partners LP | $53 717 020 | 889 944 | 1,27% | Actions |
| AMERICAN CENTURY COMPANIES INC | $53 377 571 | 884 319 | 1,26% | Actions |
| FEDERATED HERMES, INC. | $53 342 365 | 883 737 | 1,26% | Actions |
| Capital World Investors | $52 077 099 | 862 775 | 1,23% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $45 248 934 | 749 651 | 1,07% | Actions |
| Caption Management, LLC | $43 942 080 | 728 000 | 1,04% | Option d'achat |
| Vestal Point Capital, LP | $42 252 000 | 700 000 | 1,00% | Actions |
| Alyeska Investment Group, L.P. | $42 112 689 | 697 692 | 1,00% | Actions |
| Rock Springs Capital Management LP | $41 280 627 | 683 907 | 0,98% | Actions |
| PANAGORA ASSET MANAGEMENT INC | $40 080 911 | 664 031 | 0,95% | Actions |
| First Turn Management, LLC | $36 228 072 | 600 200 | 0,86% | Actions |
| TUDOR INVESTMENT CORP ET AL | $32 919 559 | 545 387 | 0,78% | Actions |
| Octagon Capital Advisors LP | $29 576 400 | 490 000 | 0,70% | Actions |
| NOVO HOLDINGS A/S | $29 301 038 | 485 438 | 0,69% | Actions |
| Candriam S.C.A. | $27 905 802 | 462 768 | 0,66% | Actions |
| Logos Global Management LP | $27 162 000 | 450 000 | 0,64% | Actions |
| Trails Edge Capital Partners, LP | $26 558 400 | 440 000 | 0,63% | Actions |
| LOOMIS SAYLES & CO L P | $26 465 868 | 438 467 | 0,63% | Actions |
| ALGERT GLOBAL LLC | $25 337 498 | 419 773 | 0,60% | Actions |
| Aberdeen Group plc | $24 671 305 | 408 736 | 0,58% | Actions |
| Parkman Healthcare Partners LLC | $23 985 796 | 397 379 | 0,57% | Actions |
| Fiera Capital Corp | $23 968 111 | 397 086 | 0,57% | Actions |
| Nicholas Investment Partners, LP | $23 893 144 | 395 844 | 0,57% | Actions |
| MILLENNIUM MANAGEMENT LLC | $22 742 260 | 376 777 | 0,54% | Actions |
| BAKER BROS. ADVISORS LP | $22 345 755 | 370 208 | 0,53% | Actions |
| Jones Hill Capital LP | $22 206 444 | 367 900 | 0,53% | Actions |
| GOLDMAN SACHS GROUP INC | $21 955 648 | 363 745 | 0,52% | Actions |
| TimesSquare Capital Management, LLC | $20 892 888 | 359 293 | 0,49% | Actions |
| AMERIPRISE FINANCIAL INC | $18 371 048 | 304 358 | 0,43% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $18 108 000 | 300 000 | 0,43% | Actions |
| Soleus Capital Management, L.P. | $16 116 120 | 267 000 | 0,38% | Actions |
| DAFNA Capital Management LLC | $15 136 598 | 250 772 | 0,36% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $15 058 190 | 249 473 | 0,36% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $15 018 836 | 248 821 | 0,36% | Actions |
| NAN FUNG TRINITY (HK) LTD | $14 955 095 | 247 765 | 0,35% | Actions |
| Redmile Group, LLC | $13 845 015 | 229 374 | 0,33% | Actions |
| Schonfeld Strategic Advisors LLC | $13 721 637 | 227 330 | 0,32% | Actions |
| D. E. Shaw & Co., Inc. | $13 515 932 | 223 922 | 0,32% | Actions |
| Patient Square Capital LP | $13 279 200 | 220 000 | 0,31% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $12 704 030 | 210 471 | 0,30% | Actions |
| JENNISON ASSOCIATES LLC | $12 558 501 | 208 060 | 0,30% | Actions |
| Trexquant Investment LP | $12 220 184 | 202 455 | 0,29% | Actions |
| DNB Asset Management AS | $12 099 222 | 200 451 | 0,29% | Actions |
| Integral Health Asset Management, LLC | $12 072 000 | 200 000 | 0,29% | Actions |
| Eversept Partners, LP | $11 862 672 | 196 532 | 0,28% | Actions |
| Balyasny Asset Management L.P. | $11 671 391 | 193 363 | 0,28% | Actions |
| TWO SIGMA ADVISERS, LP | $11 622 722 | 259 320 | 0,28% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $11 438 220 | 189 500 | 0,27% | Option d'achat |
| RENAISSANCE TECHNOLOGIES LLC | $11 293 960 | 187 110 | 0,27% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $11 276 516 | 186 821 | 0,27% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $11 066 583 | 183 343 | 0,26% | Actions |
| NEXTBio Capital Management LP | $11 059 461 | 183 225 | 0,26% | Actions |
| Iron Triangle Partners LP | $10 473 896 | 233 688 | 0,25% | Actions |
| ADAR1 Capital Management, LLC | $10 052 958 | 166 550 | 0,24% | Actions |
| PEREGRINE CAPITAL MANAGEMENT LLC | $9 953 002 | 164 894 | 0,24% | Actions |
| Swiss National Bank | $9 820 572 | 162 700 | 0,23% | Actions |
| Foresite Capital Management IV, LLC | $9 657 600 | 160 000 | 0,23% | Actions |
| Woodline Partners LP | $9 374 029 | 155 302 | 0,22% | Actions |
| BANK OF AMERICA CORP /DE/ | $9 207 133 | 152 537 | 0,22% | Actions |
| BlackRock, Inc. | $8 785 700 | 145 555 | 0,21% | Actions |
| NEUBERGER BERMAN GROUP LLC | $8 336 802 | 138 118 | 0,20% | Actions |
| Susquehanna Portfolio Strategies, LLC | $8 031 441 | 133 059 | 0,19% | Actions |
| Point72 Asset Management, L.P. | $7 869 616 | 130 378 | 0,19% | Actions |
| Granahan Investment Management, LLC | $7 813 179 | 129 443 | 0,18% | Actions |
| RHUMBLINE ADVISERS | $7 448 289 | 123 398 | 0,18% | Actions |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $7 294 370 | 121 310 | 0,17% | Actions |
| AXA Investment Managers S.A. | $7 072 704 | 176 157 | 0,17% | Actions |
| Squarepoint Ops LLC | $6 812 773 | 112 869 | 0,16% | Actions |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $6 615 637 | 109 603 | 0,16% | Actions |
| AXIOM INVESTORS LLC /DE | $6 533 246 | 108 238 | 0,15% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $6 337 800 | 105 000 | 0,15% | Actions |
| Burkehill Global Management, LP | $6 036 000 | 100 000 | 0,14% | Actions |
| ALPS ADVISORS INC | $5 891 740 | 97 610 | 0,14% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $5 606 116 | 92 878 | 0,13% | Actions |
| Bank of New York Mellon Corp | $5 469 280 | 90 611 | 0,13% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $5 393 238 | 92 747 | 0,13% | Actions |
| ExodusPoint Capital Management, LP | $5 105 913 | 84 591 | 0,12% | Actions |
| CAPITAL FUND MANAGEMENT S.A. | $5 098 609 | 84 470 | 0,12% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $4 955 556 | 82 100 | 0,12% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $4 694 197 | 77 770 | 0,11% | Actions |
| Walleye Capital LLC | $4 645 004 | 76 955 | 0,11% | Actions |
Initiés de la société 32 initiés · 15 dirigeants · 16 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Ian Mortimer | PRESIDENT & CEO | 12 mars 2026 M | 19 923 | 0 | 18 | $-21 298 042 |
| Thomas Patrick Kelly | Chief Financial Officer | 15 octobre 2025 A | — | 0 | 0 | $0 |
| Sherry Aulin | Chief Financial Officer | 18 décembre 2024 M | 0 | 0 | 0 | $0 |
| Christopher John Kenney | Chief Medical Officer | 12 mars 2026 M | 7 069 | 0 | 2 | $-244 425 |
| Andrea Difabio | Chief Legal Officer | 12 mars 2026 M | 7 301 | 0 | 2 | $-230 812 |
| Darren S Cline | Chief Commercial Officer | 9 janvier 2026 A | — | 0 | 0 | $0 |
| Christopher Von Seggern | Chief Commercial Officer | 11 mars 2024 A | 4 000 | 0 | 0 | $0 |
| James R. Empfield | EVP, Drug Discovery | 11 mars 2024 A | 10 000 | 0 | 0 | $0 |
| Sherrington Robin | EVP, Strategy & Innovation | 11 mars 2024 A | 8 398 | 0 | 0 | $0 |
| Ernesto Aycardi-Fonseca | CMO | 12 mars 2020 A | — | 0 | 0 | $0 |
| Charles J. Cohen | VP, Biology | 11 décembre 2018 M | 6 550 | 0 | 0 | $0 |
| Paul Y. Goldberg | SVP, Clinical Development | 23 octobre 2017 A | 6 000 | 0 | 0 | $0 |
| Raymond Winquist | Head, Translational Research | 18 août 2017 P | 1 000 | 0 | 0 | $0 |
| Karen G. Corraini | Gen. Counsel & Corp. Secretary | 17 mars 2015 A | — | 0 | 0 | $0 |
| Gary Bridger | EVP, Research & Development | 21 novembre 2014 A | — | 0 | 0 | $0 |
| Gillian Cannon | Administrateur | 5 juin 2026 S | 1 455 | 0 | 1 | $-63 237 |
| Gary Patou | Administrateur | 5 juin 2026 S | 24 896 | 0 | 1 | $-70 251 |
| Elizabeth A. Garofalo | Administrateur | 3 juin 2026 A | 2 645 | 0 | 0 | $0 |
| Justin D. Gover | Administrateur | 3 juin 2026 A | 2 645 | 0 | 0 | $0 |
| Dawn Svoronos | Administrateur | 3 juin 2026 A | 26 229 | 0 | 0 | $0 |
| Patrick Machado | Administrateur | 3 juin 2026 A | 2 645 | 0 | 0 | $0 |
| Mohammad Azab | Administrateur | 19 décembre 2023 M | 74 225 | 0 | 0 | $0 |
| Simon N. Pimstone | Administrateur | 2 juin 2023 A | 6 000 | 0 | 0 | $0 |
| Michael R Hayden | Administrateur | 3 juin 2021 A | 116 206 | 0 | 0 | $0 |
| Frank A Holler | Administrateur | 27 mai 2021 M | 143 653 | 0 | 0 | $0 |
| Michael M Tarnow | Administrateur | 18 mai 2021 M | 77 942 | 0 | 0 | $0 |
| Clarissa Desjardins | Administrateur | 1 juin 2020 A | — | 0 | 0 | $0 |
| Richard H Scheller | Administrateur | 16 septembre 2019 A | 7 000 | 0 | 0 | $0 |
| Johnston L Evans | Administrateur | 4 mai 2015 A | 444 655 | 0 | 0 | $0 |
| Evan A. Stein | Administrateur | 30 avril 2015 J | 4 172 | 0 | 0 | $0 |
| Associates, Llp Mx | Détenteur de 10% | 9 novembre 2014 C | 1 474 660 | 0 | 0 | $0 |
| Steven Gannon | — | 11 août 2026 S | 1 870 | 0 | 1 | $-640 600 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Détention d'ETF Détenu par 41 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| IBRN · iShares Trust | 4,76% | 5 685 SH | 8 août 2026 | Quotidien |
| SBIO · ALPS ETF Trust | 2,90% | 85 746 NS | 31 mai 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 1,92% | 14 366 NS | 31 mai 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 1,35% | 4 977 NS | 31 mai 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,94% | 6 264 NS | 30 avril 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,88% | 8 393 NS | 31 mai 2026 | N-PORT |
| GSC · Goldman Sachs ETF Trust | 0,74% | 34 036 NS | 31 mai 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,72% | 6 855 NS | 31 mai 2026 | N-PORT |
| SMMV · iShares Trust | 0,59% | 26 652 SH | 8 août 2026 | Quotidien |
| MEDI · Harbor ETF Trust | 0,50% | 2 438 NS | 30 avril 2026 | N-PORT |
| IBB · iShares Trust | 0,45% | 665 671 SH | 8 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,42% | 5 259 SH | 8 août 2026 | Quotidien |
| IWO · iShares Trust | 0,39% | 889 435 SH | 8 août 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,35% | 104 976 SH | 8 août 2026 | Quotidien |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,27% | 535 NS | 30 avril 2026 | N-PORT |
| NUSC · Nushares ETF Trust | 0,26% | 60 188 NS | 30 avril 2026 | N-PORT |
| BIB · ProShares Trust | 0,23% | 3 074 NS | 31 mai 2026 | N-PORT |
| IWM · iShares Trust | 0,20% | 2 483 574 SH | 8 août 2026 | Quotidien |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,19% | 26 381 NS | 31 mai 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,18% | 564 724 SH | 8 août 2026 | Quotidien |
| ESLG · Strategy Shares | 0,16% | 565 NS | 30 avril 2026 | N-PORT |
| RSSL · Global X Funds | 0,15% | 37 381 NS | 30 avril 2026 | N-PORT |
| ESML · iShares Trust | 0,14% | 61 538 SH | 8 août 2026 | Quotidien |
| ITWO · ProShares Trust | 0,12% | 4 067 NS | 31 mai 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,11% | 24 922 NS | 30 avril 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,09% | 3 887 SH | 8 août 2026 | Quotidien |
| FHLC · FIDELITY COVINGTON TRUST | 0,07% | 36 576 NS | 30 avril 2026 | N-PORT |
| UWM · ProShares Trust | 0,07% | 3 181 NS | 31 mai 2026 | N-PORT |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,05% | 101 NS | 31 mai 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,05% | 9 276 NS | 31 mai 2026 | N-PORT |
| URTY · ProShares Trust | 0,05% | 3 221 NS | 31 mai 2026 | N-PORT |
| PDN · Invesco Exchange-Traded Fund Trust … | 0,05% | 2 770 SH | 8 août 2026 | Quotidien |
| WSML · iShares Trust | 0,05% | 4 847 SH | 8 août 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | 0,04% | 14 319 SH | 8 août 2026 | Quotidien |
| HDG · ProShares Trust | 0,02% | 81 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 23 963 NS | 31 mai 2026 | N-PORT |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,01% | 8 110 SH | 8 août 2026 | Quotidien |
| ESGV · VANGUARD WORLD FUND | 0,01% | 21 635 SH | 8 août 2026 | Quotidien |
| IWV · iShares Trust | 0,01% | 26 801 SH | 8 août 2026 | Quotidien |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 1 120 NS | 31 mai 2026 | N-PORT |
| VT · VANGUARD INTERNATIONAL EQUITY INDEX… | 0,00% | 77 770 SH | 8 août 2026 | Quotidien |