ALMS — Pemilik institusional (13F)
Institusi yang melaporkan kepemilikan saham ini dalam SEC Form 13F triwulanan mereka. Hanya posisi panjang; satu pengaju dapat muncul dua kali untuk leg opsi terpisah. Kaki put/call offset yang besar biasanya mencerminkan pembuatan pasar atau inventaris yang dilindungi, bukan keyakinan arah.
| Institusi | Nilai | Saham | % dari 13F yang dilacak | Tipe |
|---|---|---|---|---|
| AyurMaya Capital Management Company, LP | $426.031.355 | 15.139.707 | 13,18% | Saham |
| BlackRock, Inc. | $231.258.771 | 8.218.151 | 7,16% | Saham |
| FMR LLC | $190.484.444 | 6.769.170 | 5,89% | Saham |
| Deep Track Capital, LP | $178.648.422 | 6.348.558 | 5,53% | Saham |
| SAMSARA BIOCAPITAL, LLC | $178.554.463 | 6.345.219 | 5,53% | Saham |
| Foresite Capital Management V, LLC | $165.941.439 | 5.896.995 | 5,14% | Saham |
| venBio Partners LLC | $127.429.401 | 4.528.408 | 3,94% | Saham |
| Foresite Capital Management VI LLC | $119.529.434 | 4.247.670 | 3,70% | Saham |
| VANGUARD CAPITAL MANAGEMENT LLC | $118.629.882 | 4.215.703 | 3,67% | Saham |
| Nextech Invest Ltd. | $99.643.684 | 3.540.998 | 3,08% | Saham |
| Cormorant Asset Management, LP | $92.456.671 | 3.285.596 | 2,86% | Saham |
| Saturn V Capital Management LP | $82.040.566 | 2.915.443 | 2,54% | Saham |
| Octagon Capital Advisors LP | $79.655.898 | 2.830.700 | 2,47% | Saham |
| STATE STREET CORP | $61.549.665 | 2.187.266 | 1,90% | Saham |
| GEODE CAPITAL MANAGEMENT, LLC | $61.033.791 | 2.168.517 | 1,89% | Saham |
| MPM BIOIMPACT LLC | $56.815.223 | 2.019.020 | 1,76% | Saham |
| BAKER BROS. ADVISORS LP | $56.631.750 | 2.012.500 | 1,75% | Saham |
| SR One Capital Management, LP | $55.151.473 | 1.959.896 | 1,71% | Saham |
| JANUS HENDERSON GROUP PLC | $46.790.086 | 2.124.408 | 1,45% | Saham |
| VANGUARD GROUP INC | $40.048.110 | 4.103.290 | 1,24% | Saham |
| Invesco Ltd. | $33.022.796 | 1.173.518 | 1,02% | Saham |
| NOVO HOLDINGS A/S | $30.954.000 | 1.100.000 | 0,96% | Saham |
| PRINCIPAL FINANCIAL GROUP INC | $30.055.208 | 1.068.060 | 0,93% | Saham |
| D. E. Shaw & Co., Inc. | $27.246.105 | 968.234 | 0,84% | Saham |
| UBS Group AG | $26.783.540 | 951.796 | 0,83% | Saham |
| JPMORGAN CHASE & CO | $26.407.356 | 969.617 | 0,82% | Saham |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $25.922.878 | 921.211 | 0,80% | Saham |
| Ikarian Capital, LLC | $24.497.220 | 870.548 | 0,76% | Saham |
| GREAT POINT PARTNERS LLC | $24.089.557 | 856.061 | 0,75% | Saham |
| GOLDMAN SACHS GROUP INC | $23.409.581 | 831.897 | 0,72% | Saham |
| NORTHERN TRUST CORP | $20.369.111 | 723.849 | 0,63% | Saham |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $19.701.771 | 700.134 | 0,61% | Saham |
| Integral Health Asset Management, LLC | $19.698.000 | 700.000 | 0,61% | Saham |
| MILLENNIUM MANAGEMENT LLC | $18.576.396 | 660.142 | 0,57% | Saham |
| VANGUARD FIDUCIARY TRUST CO | $17.221.961 | 612.010 | 0,53% | Saham |
| Opaleye Management Inc. | $15.477.000 | 550.000 | 0,48% | Saham |
| ORBIMED ADVISORS LLC | $15.425.307 | 548.163 | 0,48% | Saham |
| ROYCE & ASSOCIATES LP | $14.782.026 | 525.303 | 0,46% | Saham |
| Woodline Partners LP | $13.677.503 | 486.052 | 0,42% | Saham |
| Spruce Street Capital LP | $11.047.032 | 392.574 | 0,34% | Saham |
| Trium Capital LLP | $10.982.142 | 390.268 | 0,34% | Saham |
| CITIGROUP INC | $10.845.156 | 385.400 | 0,34% | Saham |
| TWO SIGMA INVESTMENTS, LP | $10.583.989 | 376.119 | 0,33% | Saham |
| MARSHALL WACE, LLP | $10.355.915 | 368.014 | 0,32% | Saham |
| Ikarian Capital, LLC | $10.026.282 | 356.300 | 0,31% | Opsi beli |
| MORGAN STANLEY | $9.037.528 | 321.163 | 0,28% | Saham |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $9.029.029 | 320.861 | 0,28% | Saham |
| Weiss Asset Management LP | $8.761.980 | 311.371 | 0,27% | Saham |
| Artia Global Partners LP | $7.838.284 | 278.546 | 0,24% | Saham |
| BARCLAYS PLC | $7.702.368 | 273.716 | 0,24% | Saham |
| Yu Fan | $7.110.190 | 252.672 | 0,22% | Saham |
| Nuveen, LLC | $6.862.558 | 243.872 | 0,21% | Saham |
| BOOTHBAY FUND MANAGEMENT, LLC | $6.825.019 | 242.538 | 0,21% | Saham |
| Omega Fund Management, LLC | $6.788.916 | 241.255 | 0,21% | Saham |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $6.427.865 | 236.841 | 0,20% | Saham |
| Bank of New York Mellon Corp | $6.377.030 | 226.618 | 0,20% | Saham |
| TOWERVIEW LLC | $6.255.353 | 222.294 | 0,19% | Saham |
| BANK OF AMERICA CORP /DE/ | $5.847.183 | 207.789 | 0,18% | Saham |
| Exome Asset Management LLC | $5.752.323 | 204.418 | 0,18% | Saham |
| DIADEMA PARTNERS LP | $5.628.000 | 200.000 | 0,17% | Opsi beli |
| HighVista Strategies LLC | $5.627.100 | 199.968 | 0,17% | Saham |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD | $5.583.008 | 1.399.250 | 0,17% | Saham |
| WELLINGTON MANAGEMENT GROUP LLP | $5.059.628 | 179.802 | 0,16% | Saham |
| WELLS FARGO & COMPANY/MN | $4.922.024 | 174.912 | 0,15% | Saham |
| Susquehanna Portfolio Strategies, LLC | $4.862.001 | 172.779 | 0,15% | Saham |
| PRUDENTIAL FINANCIAL INC | $4.575.086 | 162.583 | 0,14% | Saham |
| Russell Investments Group, Ltd. | $4.330.918 | 153.906 | 0,13% | Saham |
| Ensign Peak Advisors, Inc | $4.135.736 | 146.970 | 0,13% | Saham |
| AQR CAPITAL MANAGEMENT LLC | $4.120.736 | 146.437 | 0,13% | Saham |
| VOYA INVESTMENT MANAGEMENT LLC | $3.895.082 | 138.418 | 0,12% | Saham |
| MOORE CAPITAL MANAGEMENT, LP | $3.849.636 | 136.803 | 0,12% | Saham |
| Swiss National Bank | $3.824.226 | 135.900 | 0,12% | Saham |
| STEMPOINT CAPITAL LP | $3.819.611 | 135.736 | 0,12% | Saham |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $3.795.000 | 134.850 | 0,12% | Saham |
| VICTORY CAPITAL MANAGEMENT INC | $3.723.794 | 132.331 | 0,12% | Saham |
| Quantinno Capital Management LP | $3.688.929 | 131.092 | 0,11% | Saham |
| Elmind Capital, LP | $3.658.200 | 130.000 | 0,11% | Saham |
| STIFEL FINANCIAL CORP | $3.097.510 | 110.075 | 0,10% | Saham |
| BOOTHBAY FUND MANAGEMENT, LLC | $2.943.444 | 104.600 | 0,09% | Opsi beli |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2.820.050 | 100.215 | 0,09% | Saham |
| Caption Management, LLC | $2.814.000 | 100.000 | 0,09% | Opsi beli |
| Ghisallo Capital Management LLC | $2.814.000 | 100.000 | 0,09% | Saham |
| TD Asset Management Inc | $2.729.636 | 97.002 | 0,08% | Saham |
| RHUMBLINE ADVISERS | $2.723.010 | 96.767 | 0,08% | Saham |
| FIRST TRUST ADVISORS LP | $2.646.454 | 94.046 | 0,08% | Saham |
| Harvest Investment Services, LLC | $2.610.407 | 92.765 | 0,08% | Saham |
| Caption Management, LLC | $2.532.600 | 90.000 | 0,08% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2.490.390 | 88.500 | 0,08% | Opsi beli |
| DEUTSCHE BANK AG\ | $2.366.939 | 84.113 | 0,07% | Saham |
| ALLIANCEBERNSTEIN L.P. | $2.299.800 | 104.394 | 0,07% | Saham |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.217.939 | 78.818 | 0,07% | Saham |
| Ally Bridge Group (NY) LLC | $2.151.556 | 76.459 | 0,07% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2.040.150 | 72.500 | 0,06% | Opsi jual |
| Mariner, LLC | $2.018.263 | 71.726 | 0,06% | Saham |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $1.808.090 | 82.074 | 0,06% | Saham |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.652.296 | 58.717 | 0,05% | Saham |
| ALGERT GLOBAL LLC | $1.625.648 | 57.770 | 0,05% | Saham |
| CITADEL ADVISORS LLC | $1.581.468 | 56.200 | 0,05% | Opsi beli |
| Legal & General Group Plc | $1.545.730 | 54.930 | 0,05% | Saham |
| ACT CAPITAL MANAGEMENT, LLC | $1.452.024 | 51.600 | 0,04% | Saham |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.424.306 | 50.615 | 0,04% | Saham |
| STATE OF WISCONSIN INVESTMENT BOARD | $1.418.622 | 50.413 | 0,04% | Saham |
| Vanguard Global Advisers, LLC | $1.400.134 | 49.756 | 0,04% | Saham |
| Squarepoint Ops LLC | $1.339.183 | 47.590 | 0,04% | Saham |
| MetLife Investment Management, LLC | $1.303.220 | 46.312 | 0,04% | Saham |
| CITADEL ADVISORS LLC | $1.224.090 | 43.500 | 0,04% | Opsi jual |
| FRED ALGER MANAGEMENT, LLC | $1.211.624 | 43.057 | 0,04% | Saham |
| Creative Planning | $1.176.759 | 41.818 | 0,04% | Saham |
| JANE STREET GROUP, LLC | $1.136.856 | 40.400 | 0,04% | Opsi jual |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1.023.536 | 36.373 | 0,03% | Saham |
| Corient Private Wealth LP | $988.953 | 35.144 | 0,03% | Saham |
| Trexquant Investment LP | $960.615 | 34.137 | 0,03% | Saham |
| FRANKLIN RESOURCES INC | $918.321 | 32.634 | 0,03% | Saham |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $882.949 | 31.377 | 0,03% | Saham |
| NEW YORK STATE COMMON RETIREMENT FUND | $781.363 | 27.767 | 0,02% | Saham |
| J. Goldman & Co LP | $727.306 | 25.846 | 0,02% | Saham |
| Jain Global LLC | $710.704 | 25.256 | 0,02% | Saham |
| Y-Intercept (Hong Kong) Ltd | $710.141 | 25.236 | 0,02% | Saham |
| JANE STREET GROUP, LLC | $680.988 | 24.200 | 0,02% | Opsi beli |
| BNP PARIBAS FINANCIAL MARKETS | $677.555 | 24.078 | 0,02% | Saham |
| FOX RUN MANAGEMENT, L.L.C. | $675.163 | 23.993 | 0,02% | Saham |
| Inscription Capital, LLC | $664.076 | 23.599 | 0,02% | Saham |
| RENAISSANCE TECHNOLOGIES LLC | $656.647 | 23.335 | 0,02% | Saham |
| Police & Firemen's Retirement System of New Jersey | $655.521 | 23.295 | 0,02% | Saham |
| XTX Topco Ltd | $642.549 | 22.834 | 0,02% | Saham |
| State of New Jersey Common Pension Fund D | $616.238 | 21.899 | 0,02% | Saham |
| INTECH INVESTMENT MANAGEMENT LLC | $586.803 | 20.853 | 0,02% | Saham |
| China Universal Asset Management Co., Ltd. | $552.782 | 19.644 | 0,02% | Saham |
| ARIZONA STATE RETIREMENT SYSTEM | $525.880 | 18.688 | 0,02% | Saham |
| Vanguard Investments Australia, Ltd. | $457.894 | 16.272 | 0,01% | Saham |
| Persistent Asset Partners Ltd | $443.667 | 508 | 0,01% | Opsi beli |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $433.243 | 15.396 | 0,01% | Saham |
| OCCUDO QUANTITATIVE STRATEGIES LP | $430.458 | 15.297 | 0,01% | Saham |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $422.100 | 15.000 | 0,01% | Saham |
| Brevan Howard Capital Management LP | $416.782 | 14.811 | 0,01% | Saham |
| ProShare Advisors LLC | $405.020 | 14.393 | 0,01% | Saham |
| PROFUND ADVISORS LLC | $401.023 | 14.251 | 0,01% | Saham |
| OpenArc Corporate Advisory, LLC | $400.714 | 14.240 | 0,01% | Saham |
| KLP KAPITALFORVALTNING AS | $399.588 | 14.200 | 0,01% | Saham |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $382.817 | 13.604 | 0,01% | Saham |
| Virtus Investment Advisers, LLC | $381.269 | 13.549 | 0,01% | Saham |
| TWO SIGMA ADVISERS, LP | $371.602 | 38.074 | 0,01% | Saham |
| Point72 Asset Management, L.P. | $343.308 | 12.200 | 0,01% | Opsi beli |
| Point72 Asset Management, L.P. | $343.308 | 12.200 | 0,01% | Opsi jual |
| Verdad Advisers, LP | $342.942 | 12.187 | 0,01% | Saham |
| MERCER GLOBAL ADVISORS INC /ADV | $322.119 | 11.447 | 0,01% | Saham |
| SmartHarvest Portfolios, LLC | $303.096 | 10.771 | 0,01% | Saham |
| Allianz Asset Management GmbH | $301.098 | 10.700 | 0,01% | Saham |
| Vanguard Personalized Indexing Management, LLC | $300.169 | 10.667 | 0,01% | Saham |
| Voleon Capital Management LP | $299.550 | 10.645 | 0,01% | Saham |
| Pictet Asset Management Holding SA | $295.217 | 10.491 | 0,01% | Saham |
| Rafferty Asset Management, LLC | $278.670 | 9.903 | 0,01% | Saham |
| CAPSTONE INVESTMENT ADVISORS, LLC | $236.967 | 8.421 | 0,01% | Saham |
| SEI INVESTMENTS CO | $234.621 | 8.337 | 0,01% | Saham |
| Vident Advisory, LLC | $233.449 | 8.296 | 0,01% | Saham |
| CWM, LLC | $228.870 | 10.389 | 0,01% | Saham |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $222.081 | 7.892 | 0,01% | Saham |
| Arax Advisory Partners | $221.884 | 7.885 | 0,01% | Saham |
| XPONANCE LLC | $218.113 | 7.751 | 0,01% | Saham |
| HAP Trading, LLC | $213.125 | 402.500 | 0,01% | Opsi jual |
| Abel Hall, LLC | $209.277 | 7.437 | 0,01% | Saham |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $201.794 | 7.128 | 0,01% | Saham |
| Ameritas Investment Partners, Inc. | $201.708 | 7.168 | 0,01% | Saham |
| Fulcrum Asset Management LLP | $193.128 | 7.116 | 0,01% | Saham |
| State of Wyoming | $188.876 | 6.712 | 0,01% | Saham |
| Farther Finance Advisors, LLC | $174.890 | 6.215 | 0,01% | Saham |
| Mirae Asset Global Investments Co., Ltd. | $155.333 | 5.520 | 0,00% | Saham |
| Tower Research Capital LLC (TRC) | $153.279 | 5.447 | 0,00% | Saham |
| PRICE T ROWE ASSOCIATES INC /MD/ | $146.325 | 5.199.838 | 0,00% | Saham |
| SIMPLEX TRADING, LLC | $140.306 | 4.986 | 0,00% | Saham |
| ASSETMARK, INC | $118.441 | 4.209 | 0,00% | Saham |
| GF FUND MANAGEMENT CO. LTD. | $75.331 | 2.677 | 0,00% | Saham |
| STRS OHIO | $73.164 | 2.600 | 0,00% | Saham |
| EverSource Wealth Advisors, LLC | $72.630 | 2.581 | 0,00% | Saham |
| ROYAL BANK OF CANADA | $72.000 | 2.559 | 0,00% | Saham |
| Parallel Advisors, LLC | $57.940 | 2.059 | 0,00% | Saham |
| SIGNATUREFD, LLC | $36.188 | 1.286 | 0,00% | Saham |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $32.839 | 1.167 | 0,00% | Saham |
| GAMMA Investing LLC | $27.971 | 994 | 0,00% | Saham |
| JONES FINANCIAL COMPANIES LLLP | $27.852 | 1.055 | 0,00% | Saham |
| NISA INVESTMENT ADVISORS, LLC | $27.774 | 987 | 0,00% | Saham |
| Kemnay Advisory Services Inc. | $25.664 | 912 | 0,00% | Saham |
| Global Retirement Partners, LLC | $15.280 | 543 | 0,00% | Saham |
| Allworth Financial LP | $13.142 | 467 | 0,00% | Saham |
| Essential Partners LLC | $12.382 | 440 | 0,00% | Saham |
| ROTHSCHILD INVESTMENT LLC | $11.566 | 411 | 0,00% | Saham |
| PNC Financial Services Group, Inc. | $11.031 | 392 | 0,00% | Saham |
| Aster Capital Management (DIFC) Ltd | $9.258 | 329 | 0,00% | Saham |
| COMERICA BANK | $9.096 | 932 | 0,00% | Saham |
| OSAIC HOLDINGS, INC. | $8.188 | 291 | 0,00% | Saham |
| MassMutual Private Wealth & Trust, FSB | $7.851 | 279 | 0,00% | Saham |
| Sterling Capital Management LLC | $7.795 | 277 | 0,00% | Saham |
| US BANCORP \DE\ | $7.401 | 263 | 0,00% | Saham |
| True Wealth Design, LLC | $6.529 | 232 | 0,00% | Saham |
| BFSG, LLC | $5.403 | 192 | 0,00% | Saham |
| Larson Financial Group LLC | $4.334 | 154 | 0,00% | Saham |
| Versant Capital Management, Inc | $4.013 | 543 | 0,00% | Saham |
| Parkside Financial Bank & Trust | $3.994 | 142 | 0,00% | Saham |
| Transamerica Financial Advisors, LLC | $2.729 | 97 | 0,00% | Saham |
| Quarry LP | $2.701 | 96 | 0,00% | Saham |
| Optiver Holding B.V. | $2.645 | 94 | 0,00% | Saham |
| Decker Retirement Planning Inc. | $2.561 | 91 | 0,00% | Saham |
| Fortitude Family Office, LLC | $2.167 | 77 | 0,00% | Saham |
| IFP Advisors, Inc | $1.548 | 55 | 0,00% | Saham |
| SBI Securities Co., Ltd. | $957 | 34 | 0,00% | Saham |
| Silver Grove Financial Group, Inc. | $900 | 32 | 0,00% | Saham |
| CoreCap Advisors, LLC | $732 | 26 | 0,00% | Saham |
| NATIONAL BANK OF CANADA /FI/ | $703 | 25 | 0,00% | Saham |
| SG Americas Securities, LLC | $643 | 22.867 | 0,00% | Saham |
| HARBOUR INVESTMENTS, INC. | $634 | 23 | 0,00% | Saham |
| Stone House Investment Management, LLC | $619 | 22 | 0,00% | Saham |
| SALEM INVESTMENT COUNSELORS INC | $563 | 20 | 0,00% | Saham |
| HAP Trading, LLC | $272 | 340.000 | 0,00% | Opsi jual |
| HAP Trading, LLC | $260 | 266.900 | 0,00% | Opsi beli |
| Sunbelt Securities, Inc. | $154 | 7 | 0,00% | Saham |
| ACADIAN ASSET MANAGEMENT LLC | $103 | 3.696 | 0,00% | Saham |
| KBC Group NV | $54 | 1.929 | 0,00% | Saham |
| Covestor Ltd | $1 | 28 | 0,00% | Saham |