| BAKER BROS. ADVISORS LP |
$259145283 |
33012138 |
27.38% |
股份
|
| Capital World Investors |
$106668540 |
13588349 |
11.27% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$81933833 |
10437431 |
8.66% |
股份
|
| TD Waterhouse Canada Inc. |
$72623873 |
9568149 |
7.67% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$48211081 |
6141539 |
5.09% |
股份
|
| ArrowMark Colorado Holdings LLC |
$32224996 |
4105095 |
3.40% |
股份
|
| BlackRock, Inc. |
$29871676 |
3805309 |
3.16% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$26438411 |
7575476 |
2.79% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$22655100 |
2886000 |
2.39% |
买入期权
|
| Driehaus Capital Management LLC |
$22488123 |
2864729 |
2.38% |
股份
|
| TWO SIGMA ADVISERS, LP |
$16682760 |
4878000 |
1.76% |
股份
|
| TUDOR INVESTMENT CORP ET AL |
$16196049 |
2063191 |
1.71% |
股份
|
| MARSHALL WACE, LLP |
$14932200 |
1902191 |
1.58% |
股份
|
| UBS Group AG |
$14684469 |
1870633 |
1.55% |
股份
|
| MORGAN STANLEY |
$13101760 |
1669014 |
1.38% |
股份
|
| CITADEL ADVISORS LLC |
$12454119 |
1586512 |
1.32% |
股份
|
| NATIONAL BANK OF CANADA /FI/ |
$9679124 |
1233014 |
1.02% |
股份
|
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
$8163427 |
1039927 |
0.86% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$7778793 |
990929 |
0.82% |
股份
|
| Counterpoint Mutual Funds LLC |
$7627398 |
971643 |
0.81% |
股份
|
| CITADEL ADVISORS LLC |
$6203855 |
790300 |
0.66% |
买入期权
|
| STATE STREET CORP |
$5741192 |
731362 |
0.61% |
股份
|
| DNB Asset Management AS |
$5318210 |
677479 |
0.56% |
股份
|
| Guardian Partners Inc. |
$4678584 |
595998 |
0.49% |
股份
|
| Daiwa Securities Group Inc. |
$4407775 |
561500 |
0.47% |
卖出期权
|
| Intellectus Partners, LLC |
$4329925 |
551583 |
0.46% |
股份
|
| Alyeska Investment Group, L.P. |
$4133629 |
526577 |
0.44% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$4070782 |
518571 |
0.43% |
股份
|
| BANK OF MONTREAL /CAN/ |
$3789972 |
482799 |
0.40% |
股份
|
| Sculptor Capital LP |
$3563900 |
454000 |
0.38% |
股份
|
| Sculptor Capital LP |
$3563900 |
454000 |
0.38% |
卖出期权
|
| OSAIC HOLDINGS, INC. |
$3201970 |
407898 |
0.34% |
股份
|
| ROYAL BANK OF CANADA |
$3167000 |
403324 |
0.33% |
股份
|
| BANK OF MONTREAL /CAN/ |
$3164335 |
403100 |
0.33% |
卖出期权
|
| STATE OF MICHIGAN RETIREMENT SYSTEM |
$3140000 |
400000 |
0.33% |
股份
|
| CITADEL ADVISORS LLC |
$2922555 |
372300 |
0.31% |
卖出期权
|
| SOFTBANK GROUP CORP. |
$2709514 |
345161 |
0.29% |
股份
|
| Decker Retirement Planning Inc. |
$2638479 |
336112 |
0.28% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$2478409 |
315721 |
0.26% |
股份
|
| Daiwa Securities Group Inc. |
$2445275 |
311500 |
0.26% |
股份
|
| NORTHERN TRUST CORP |
$2344128 |
298615 |
0.25% |
股份
|
| Daiwa Securities Group Inc. |
$1962500 |
250000 |
0.21% |
买入期权
|
| Headlands Technologies LLC |
$1933078 |
246252 |
0.20% |
股份
|
| ExodusPoint Capital Management, LP |
$1867923 |
237952 |
0.20% |
股份
|
| GOLDMAN SACHS GROUP INC |
$1845747 |
235127 |
0.20% |
股份
|
| Man Group plc |
$1797485 |
228979 |
0.19% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$1694030 |
215800 |
0.18% |
卖出期权
|
| CITIZENS FINANCIAL GROUP INC/RI |
$1663337 |
211890 |
0.18% |
股份
|
| UBS Group AG |
$1570000 |
200000 |
0.17% |
卖出期权
|
| GROUP ONE TRADING LLC |
$1560525 |
198793 |
0.16% |
股份
|
| JANE STREET GROUP, LLC |
$1532807 |
195262 |
0.16% |
股份
|
| JANE STREET GROUP, LLC |
$1303885 |
166100 |
0.14% |
卖出期权
|
| Jump Financial, LLC |
$989100 |
126000 |
0.10% |
股份
|
| HSBC HOLDINGS PLC |
$929288 |
117930 |
0.10% |
股份
|
| ArchPoint Investors |
$903182 |
115055 |
0.10% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$855736 |
109011 |
0.09% |
股份
|
| HighTower Advisors, LLC |
$847274 |
107933 |
0.09% |
股份
|
| STIFEL FINANCIAL CORP |
$833579 |
106188 |
0.09% |
股份
|
| COOKSON PEIRCE & CO INC |
$785000 |
100000 |
0.08% |
股份
|
| JANE STREET GROUP, LLC |
$736330 |
93800 |
0.08% |
买入期权
|
| LPL Financial LLC |
$702583 |
89501 |
0.07% |
股份
|
| BARCLAYS PLC |
$664376 |
84634 |
0.07% |
股份
|
| Quantbot Technologies LP |
$627647 |
79955 |
0.07% |
股份
|
| PIER 88 INVESTMENT PARTNERS LLC |
$627215 |
79900 |
0.07% |
股份
|
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
$560058 |
71345 |
0.06% |
股份
|
| CAXTON ASSOCIATES LLP |
$521067 |
66378 |
0.06% |
股份
|
| Erste Asset Management GmbH |
$503440 |
62000 |
0.05% |
股份
|
| HERITAGE OAK WEALTH ADVISORS LLC |
$502400 |
64000 |
0.05% |
股份
|
| Virtus Investment Advisers, LLC |
$490170 |
62442 |
0.05% |
股份
|
| WELLS FARGO & COMPANY/MN |
$473630 |
60335 |
0.05% |
股份
|
| Voleon Capital Management LP |
$466259 |
59396 |
0.05% |
股份
|
| Resolute Advisors LLC |
$451579 |
57526 |
0.05% |
股份
|
| XML Financial, LLC |
$447646 |
57025 |
0.05% |
股份
|
| WINTON GROUP Ltd |
$441955 |
56300 |
0.05% |
股份
|
| Y-Intercept (Hong Kong) Ltd |
$425415 |
54193 |
0.04% |
股份
|
| Militia Capital Management LLC |
$423900 |
54000 |
0.04% |
股份
|
| Invesco Ltd. |
$390561 |
49753 |
0.04% |
股份
|
| China Universal Asset Management Co., Ltd. |
$381518 |
48601 |
0.04% |
股份
|
| Walleye Capital LLC |
$363455 |
46300 |
0.04% |
买入期权
|
| Tradition Wealth Management, LLC |
$360770 |
45958 |
0.04% |
股份
|
| D. E. Shaw & Co., Inc. |
$356633 |
45431 |
0.04% |
股份
|
| Walleye Trading LLC |
$350181 |
44609 |
0.04% |
股份
|
| Creative Planning |
$336198 |
42828 |
0.04% |
股份
|
| Caitong International Asset Management Co., Ltd |
$326811 |
41632 |
0.03% |
股份
|
| Atlatl Advisers LLC |
$314000 |
40000 |
0.03% |
股份
|
| Apollon Wealth Management, LLC |
$314000 |
40000 |
0.03% |
股份
|
| Cerity Partners LLC |
$312422 |
39799 |
0.03% |
股份
|
| Federation des caisses Desjardins du Quebec |
$267681 |
34145 |
0.03% |
股份
|
| OneDigital Investment Advisors LLC |
$266900 |
34000 |
0.03% |
股份
|
| RAYMOND JAMES FINANCIAL INC |
$260620 |
33200 |
0.03% |
股份
|
| MOR Wealth Management, LLC |
$259050 |
33000 |
0.03% |
股份
|
| OXFORD ASSET MANAGEMENT LLP |
$243852 |
31064 |
0.03% |
股份
|
| Golden State Wealth Management, LLC |
$235500 |
30000 |
0.02% |
股份
|
| State of Wyoming |
$234935 |
29928 |
0.02% |
股份
|
| BRANDYWINE MANAGERS, LLC |
$223631 |
28488 |
0.02% |
股份
|
| Hilltop Holdings Inc. |
$218505 |
27835 |
0.02% |
股份
|
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. |
$212672 |
27092 |
0.02% |
股份
|
| SCOTIA CAPITAL INC. |
$196894 |
25082 |
0.02% |
股份
|
| JPMORGAN CHASE & CO |
$177431 |
21851 |
0.02% |
股份
|
| Networth Advisors, LLC |
$176829 |
22526 |
0.02% |
股份
|
| Stratos Wealth Advisors, LLC |
$176625 |
22500 |
0.02% |
股份
|
| Green Alpha Advisors, LLC |
$172041 |
21916 |
0.02% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$161553 |
20580 |
0.02% |
股份
|
| Intesa Sanpaolo S.p.A. |
$155870 |
20000 |
0.02% |
股份
|
| HBK Sorce Advisory LLC |
$155003 |
26183 |
0.02% |
股份
|
| VestGen Advisors, LLC |
$154268 |
19652 |
0.02% |
股份
|
| SIMPLEX TRADING, LLC |
$153075 |
19500 |
0.02% |
股份
|
| Ballentine Partners, LLC |
$146450 |
18656 |
0.02% |
股份
|
| CIBC WORLD MARKET INC. |
$135381 |
17246 |
0.01% |
股份
|
| IMC-Chicago, LLC |
$135059 |
17205 |
0.01% |
股份
|
| Clear Creek Financial Management, LLC |
$133843 |
17050 |
0.01% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$127649 |
16261 |
0.01% |
股份
|
| Brevan Howard Capital Management LP |
$123810 |
15772 |
0.01% |
股份
|
| Scientech Research LLC |
$120921 |
15404 |
0.01% |
股份
|
| Ausdal Financial Partners, Inc. |
$119062 |
15167 |
0.01% |
股份
|
| Walleye Capital LLC |
$118535 |
15100 |
0.01% |
卖出期权
|
| ROTHSCHILD INVESTMENT LLC |
$116926 |
14895 |
0.01% |
股份
|
| NewEdge Advisors, LLC |
$116588 |
14852 |
0.01% |
股份
|
| Mirae Asset Global Investments Co., Ltd. |
$107215 |
13658 |
0.01% |
股份
|
| SBI Securities Co., Ltd. |
$98525 |
12551 |
0.01% |
股份
|
| KESTRA PRIVATE WEALTH SERVICES, LLC |
$91845 |
11700 |
0.01% |
股份
|
| Allworth Financial LP |
$91398 |
11643 |
0.01% |
股份
|
| FOX RUN MANAGEMENT, L.L.C. |
$87732 |
11176 |
0.01% |
股份
|
| Private Advisor Group, LLC |
$82033 |
10450 |
0.01% |
股份
|
| AssuredPartners Investment Advisors, LLC |
$79968 |
10187 |
0.01% |
股份
|
| SIGNATUREFD, LLC |
$79583 |
10138 |
0.01% |
股份
|
| ProShare Advisors LLC |
$78586 |
10011 |
0.01% |
股份
|
| &PARTNERS |
$78500 |
10000 |
0.01% |
股份
|
| Lantern Wealth Advisors, LLC |
$78500 |
10000 |
0.01% |
股份
|
| DKM Wealth Management, Inc. |
$78500 |
10000 |
0.01% |
股份
|
| Rockefeller Capital Management L.P. |
$75179 |
9577 |
0.01% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$67314 |
8575 |
0.01% |
股份
|
| CITIGROUP INC |
$56379 |
7182 |
0.01% |
股份
|
| Farther Finance Advisors, LLC |
$52162 |
6645 |
0.01% |
股份
|
| GF FUND MANAGEMENT CO. LTD. |
$50350 |
6414 |
0.01% |
股份
|
| Bayforest Capital Ltd |
$46244 |
5891 |
0.00% |
股份
|
| Blume Capital Management, Inc. |
$35200 |
4484 |
0.00% |
股份
|
| IFP Advisors, Inc |
$32436 |
4132 |
0.00% |
股份
|
| Parallel Advisors, LLC |
$31628 |
4029 |
0.00% |
股份
|
| Russell Investments Group, Ltd. |
$26933 |
3431 |
0.00% |
股份
|
| Pacifica Partners Inc. |
$18063 |
2230 |
0.00% |
股份
|
| LANARK FINANCIAL, INC. |
$15700 |
2000 |
0.00% |
股份
|
| Tradewinds Capital Management, LLC |
$14421 |
1837 |
0.00% |
股份
|
| Stone House Investment Management, LLC |
$13369 |
1703 |
0.00% |
股份
|
| EFG International AG |
$13345 |
1700 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$12465 |
1587870 |
0.00% |
股份
|
| Cornerstone Planning Group LLC |
$11460 |
2000 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$9277 |
1257 |
0.00% |
股份
|
| Tower Research Capital LLC (TRC) |
$8643 |
1101 |
0.00% |
股份
|
| Princeton Global Asset Management LLC |
$7850 |
1000 |
0.00% |
股份
|
| HRT FINANCIAL LP |
$5538 |
705506 |
0.00% |
股份
|
| US BANCORP \DE\ |
$4796 |
611 |
0.00% |
股份
|
| Walleye Trading LLC |
$4710 |
600 |
0.00% |
买入期权
|
| Tradition Wealth Management, LLC |
$3925 |
500 |
0.00% |
买入期权
|
| Cape Investment Advisory, Inc. |
$3925 |
500 |
0.00% |
股份
|
| Arax Advisory Partners |
$2976 |
379 |
0.00% |
股份
|
| Lindbrook Capital, LLC |
$2255 |
1011 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$1659 |
211370 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$1357 |
173062 |
0.00% |
股份
|
| GILL CAPITAL PARTNERS, LLC |
$785 |
100 |
0.00% |
股份
|
| HARBOUR INVESTMENTS, INC. |
$766 |
98 |
0.00% |
股份
|
| Continuum Advisory, LLC |
$730 |
93 |
0.00% |
股份
|
| Handelsbanken Fonder AB |
$404 |
115700 |
0.00% |
股份
|
| Walleye Capital LLC |
$71 |
9 |
0.00% |
股份
|
| Larson Financial Group LLC |
$55 |
7 |
0.00% |
股份
|