TVTX Travere Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · Auf SEC EDGAR ansehen ↗
$63,55
Kurs · Aug 18, 2026
Fundamentaldaten per Aug 4, 2026

TVTX Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne

Kurs
$63.55
Marktkapitalisierung
$5.78B
P/E (TTM)
-219.1
EPS (TTM)
$-0.29
Umsatz (TTM)
$491M
Dividendenrendite
ROE
-34.6%
Verschuldungsgrad
52W-Spanne
$17 – $66

TVTX Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen

10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends

Umsatz & Nettoergebnis $491M
10-point trend, +267.3%
2016-12-31 2025-12-31
EPS $-0.29
10-point trend, +77.5%
2016-12-31 2025-12-31
Freier Cashflow
8-point trend, -9182.0%
2016-12-31 2023-12-31
Margen -5.2%

Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?

Kennzahl
5-Jahres-Trend
TVTX
Peer-Median
P/E (TTM)
5-point trend, -1177.7%
-219.1
37.2
P/S (TTM) (K/V (TTM))
5-point trend, -51.9%
11.8
9.9
P/B (K/B)
5-point trend, +371.2%
50.3
8.3

Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC

Kennzahl
5-Jahres-Trend
TVTX
Peer-Median
Operating Margin (Betriebsgewinnmarge)
5-point trend, +82.0%
-12.8%
Net Profit Margin (Nettogewinnmarge)
5-point trend, +93.4%
-5.2%
-15.1%
ROA
5-point trend, +83.6%
-4.3%
-23.3%
ROE
5-point trend, +41.4%
-34.6%
-30.6%
ROIC
5-point trend, -4.0%
-55.8%

Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke

Kennzahl
5-Jahres-Trend
TVTX
Peer-Median
Current Ratio (Liquiditätsgrad)
5-point trend, -41.7%
2.7
6.3
Quick Ratio
5-point trend, -26.0%
1.1

Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR

Kennzahl
5-Jahres-Trend
TVTX
Peer-Median
Revenue YoY (Umsatz YoY)
5-point trend, +272.2%
110.5%
Revenue CAGR 3Y (Umsatz CAGR 3J)
5-point trend, +272.2%
64.9%
Revenue CAGR 5Y (Umsatz CAGR 5J)
5-point trend, +272.2%
19.9%

Kennzahlen pro Aktie EPS, Buchwert pro Aktie, Cashflow pro Aktie, Dividende pro Aktie

Kennzahl
5-Jahres-Trend
TVTX
Peer-Median
EPS (Diluted) (EPS (Verwässert))
5-point trend, +90.4%
$-0.29

Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag

Kennzahl
5-Jahres-Trend
TVTX
Peer-Median

TVTX Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial

KAUF 21 Analysten
  • Starker Kauf 8 38,1%
  • Kauf 11 52,4%
  • Halten 2 9,5%
  • Verkauf 0 0,0%
  • Starker Verkauf 0 0,0%

12-Monats-Kursziel

14 Analysten · 2026-08-14
Median-Ziel $75.00 +18,0%
Mittelwert-Ziel $72.79 +14,5%

Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum

Durchschn. Überraschung
0.16%
Zeitraum EPS Actual EPS est. Überraschung
30. Juni 2026 $0.06 $-0.14 0.20%
31. März 2026 $-0.40 $-0.27 -0.13%
31. Dezember 2025 $0.03 $-0.12 0.15%
30. September 2025 $0.28 $-0.21 0.49%
30. Juni 2025 $-0.14 $-0.30 0.16%
31. März 2025 $-0.47 $-0.55 0.08%

Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen

Ticker Marktkapitalisierung P/E Umsatz Vj. Nettomarge ROE Bruttogewinnmarge
TVTX $3.47B -131.8 110.5% -5.2% -34.6%
ERAS $1.06B -8.5 -35.7%
SRRK $4.78B -13.4 -157.9%
DNTH $1.78B -9.8 -67.3% -7973.3% -40.8%
CAI $7.62B -8.4 97.0% -8.4% -13.2%
PTCT $6.19B 9.8 114.5% 39.4% -331.5%
ACAD $4.55B 11.6 11.9% 36.5% 38.1%
DYN $3.23B -5.6 -57.8%
CELC $4.81B -26.3 -244.3%

Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow

Gewinn- und Verlustrechnung 17
Jährliche Gewinn- und Verlustrechnung-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +1640.0% $491M $233M $145M $109M $132M $198M $175M $164M $155M $134M $100M $28M
Cost of Revenue 12-point trend, +1710.7% $10M $8M $11M $4M $4M $6M $5M $6M $4M $5M $2M $571.0K
R&D Expense 7-point trend, -84.3% · · · $8M · · $141M $124M $78M $71M $50M $48M
SG&A Expense 12-point trend, +465.3% $337M $264M $266M $198M $126M $136M $129M $104M $101M $92M $80M $60M
Operating Expenses 12-point trend, +412.5% $554M $557M $533M $429M $331M $374M $313M $244M $209M $192M $151M $108M
Operating Income 12-point trend, +21.3% $-63M $-324M $-388M $-320M $-199M $-176M $-137M $-80M $-54M $-58M $-51M $-80M
Interest Expense 10-point trend, +52.7% · · $11M $11M $20M $19M $19M $10M $4M $5M $8M $7M
Interest Income 9-point trend, +293.4% $13M $18M $22M $6M $2M $5M $10M $5M $3M · · ·
Other Non-op 12-point trend, +392.3% $12M $-3M $2M $974.0K $231.0K $1M $-314.0K $-474.0K $1M $-264.0K $-296.0K $2M
Pretax Income 12-point trend, +56.5% $-49M $-321M $-376M $-331M $-217M $-189M $-146M $-102M $-58M $-58M $105M $-113M
Income Tax 12-point trend, +140.2% $988.0K $120.0K $223.0K $313.0K $409.0K $-19M $-21.0K $811.0K $1M $-10M $-12M $-2M
Net Income 12-point trend, +77.0% $-26M $-322M $-111M $-278M $-180M $-169M $-146M $-103M $-60M $-48M $117M $-111M
EPS (Basic) 12-point trend, +93.5% $-0.29 $-4.08 $-1.50 $-4.37 $-3.01 $-3.56 $-3.46 $-2.54 $-1.54 $-1.29 $3.49 $-4.43
EPS (Diluted) 12-point trend, +93.5% $-0.29 $-4.08 $-1.50 $-4.37 $-3.01 $-3.56 $-3.46 $-2.54 $-1.54 $-1.29 $3.17 $-4.43
Shares (Basic) 12-point trend, +256.0% 89,211,813 78,888,861 74,267,418 63,758,515 59,832,287 47,539,631 42,339,961 40,433,171 38,769,816 36,997,865 33,560,249 25,057,509
Shares (Diluted) 12-point trend, +256.0% 89,211,813 78,888,861 74,267,418 63,758,515 59,832,287 47,539,631 42,339,961 40,433,171 38,769,816 38,288,012 37,581,439 25,057,509
EBITDA 10-point trend, +95.1% $-2M $-280M $-350M $-233M $-135M $-152M $-117M $-61M $-36M $-42M · ·
Bilanz 29
Jährliche Bilanz-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +411.1% $93M $59M $58M $62M $166M $85M $62M $103M $99M $41M $38M $18M
Short-term Investments 4-point trend, +2005.9% · · · · · · · · $201M $215M $192M $10M
Receivables 12-point trend, +906.7% $80M $27M $21M $17M $16M $16M $18M $13M $14M $19M $12M $8M
Inventory 12-point trend, +4413.7% $36M $42M $9M $5M $7M $8M $6M $6M $5M $3M $3M $801.0K
Prepaid Expense 12-point trend, +3437.5% $29M $13M $19M $12M $7M $8M $5M $4M $3M $5M $2M $813.0K
Current Assets 12-point trend, +1072.0% $438M $417M $617M $486M $583M $410M $429M $496M $326M $332M $302M $37M
PP&E (Net) 12-point trend, +499.4% $4M $5M $7M $9M $11M $9M $3M $3M $3M $3M $428.0K $671.0K
PP&E (Gross) 10-point trend, +406.6% $14M $14M $15M $14M $14M $13M $5M $4M $4M $3M · ·
Accum. Depreciation 10-point trend, +4949.0% $10M $9M $7M $5M $3M $4M $2M $1M $585.0K $200.0K · ·
Goodwill 11-point trend, -14.5% · $800.0K $800.0K $800.0K $900.0K $900.0K $936.0K $936.0K $936.0K $936.0K $936.0K $936.0K
Intangibles 12-point trend, +20.8% $114M $104M $104M $97M $148M $154M $157M $187M $185M $182M $162M $94M
Other Non-current Assets 12-point trend, +292.1% $9M $18M $11M $11M $11M $8M $15M $8M $6M $7M $2M $2M
Total Assets 12-point trend, +346.7% $605M $594M $789M $673M $777M $607M $605M $709M $520M $525M $512M $135M
Accounts Payable 12-point trend, +248.1% $25M $24M $42M $17M $15M $12M $27M $7M $19M $8M $8M $7M
Accrued Liabilities 12-point trend, +352.0% $126M $86M $119M $96M $75M $57M $52M $50M $36M $33M $24M $28M
Short-term Debt 2-point trend, -100.0% · · · · · · · · · · $0 $40M
Current Liabilities 12-point trend, +48.7% $160M $201M $178M $142M $124M $93M $95M $105M $86M $83M $87M $108M
Capital Leases 7-point trend, +50.6% $11M $17M $23M $28M $31M $28M $7M · · · · ·
Deferred Tax 4-point trend, -100.0% · · · · · · · · $0 $6M $24M $141.0K
Other Non-current Liabilities 12-point trend, +370.1% $8M $7M $10M $9M $12M $12M $21M $18M $2M $4M $3M $2M
Total Liabilities 12-point trend, +183.9% $490M $535M $588M $630M $475M $396M $384M $391M $227M $218M $212M $173M
Common Stock 12-point trend, +200.0% $9.0K $9.0K $7.0K $6.0K $6.0K $5.0K $4.0K $4.0K $4.0K $4.0K $4.0K $3.0K
Paid-in Capital 12-point trend, +1027.9% $1.59B $1.51B $1.33B $1.06B $1.07B $798M $637M $590M $472M $421M $366M $141M
Retained Earnings 12-point trend, -721.9% $-1.47B $-1.45B $-1.13B $-1.01B $-766M $-586M $-416M $-270M $-178M $-113M $-65M $-179M
Treasury Stock 2-point trend, -100.0% · · · · · · · · · · $0 $3M
AOCI 12-point trend, -127.7% $-1M $-80.0K $-1M $-3M $-562.0K $-902.0K $726.0K $-2M $-1M $-490.0K $-682.0K $4M
Stockholders' Equity 12-point trend, +408.3% $115M $59M $201M $43M $302M $211M $221M $318M $293M $308M $300M $-37M
Liabilities + Equity 12-point trend, +346.7% $605M $594M $789M $673M $777M $607M $605M $709M $520M $525M $512M $135M
Shares Outstanding 12-point trend, +249.1% 90,922,868 87,452,835 75,367,117 64,290,570 62,491,498 52,248,431 43,088,921 41,389,524 39,373,745 37,906,669 36,465,853 26,048,480
Cashflow 18
Jährliche Cashflow-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, +1024.7% $61M $44M $39M $21M $13M $25M $20M $19M $18M $16M $13M $5M
Stock-based Comp 12-point trend, +182.2% $45M $37M $44M $38M $30M $24M $21M $20M $27M $29M $26M $16M
Deferred Tax 12-point trend, +100.0% $0 $0 $0 $0 $0 $0 $0 $0 $-6M $-23M $-16M $-2M
Amort. of Intangibles 12-point trend, +1021.8% $59M $42M $36M $19M $11M $22M $20M $18M $17M $16M $13M $5M
Restructuring 11-point trend, +0.00 $0 $2M $11M $0 $0 $0 $0 $-242.0K $4M $893.0K $0 ·
Other Non-cash 10-point trend, -278.2% $-42M $4M $-251M $20M $108M $78M $47M $39M $29M $24M · ·
Operating Cash Flow 12-point trend, +182.4% $38M $-237M $-280M $-186M $-15M $-43M $-58M $-25M $7M $-3M $-1M $-46M
CapEx 10-point trend, +0.8% · · $668.0K $191.0K $5M $7M $195.0K $727.0K $887.0K $1M $22.0K $663.0K
Investing Cash Flow 11-point trend, +134.6% $28M $99M $56M $-33M $-138M $-61M $20M $-203M $46M $10M $-81M ·
Net Debt Issued 3-point trend, +100.0% · · · · · $0 $0 $-40M · · · ·
Stock Issued 9-point trend, -100.0% $0 $135M $191M $0 $189M · · · $0 $0 $149M $40M
Stock Repurchased 3-point trend, -100.0% · · · · · · · · · $0 $0 $2M
Net Stock Activity 5-point trend, +0.00 $0 $135M $191M · · · · · $0 $0 · ·
Financing Cash Flow 12-point trend, -135.1% $-33M $139M $219M $118M $232M $128M $-2M $232M $5M $-4M $102M $95M
Net Change in Cash 12-point trend, +182.6% $34M $359.0K $-4M $-104M $81M $22M $-40M $3M $58M $3M $20M $12M
Taxes Paid 7-point trend, +107.8% · $453.0K $578.0K $996.0K $-16M $-3M $656.0K $218.0K · · · ·
Free Cash Flow 8-point trend, -9182.0% · · $-281M $-186M $-20M $-50M $-58M $-26M $7M $-3M · ·
Levered FCF 8-point trend, -7814.2% · · $-292M $-198M $-40M $-67M $-77M $-36M $5M $-4M · ·
Rentabilität 7
Jährliche Rentabilität-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Operating Margin 10-point trend, +70.6% -12.8% -138.9% -267.2% -125.7% -71.1% -88.8% -78.3% -48.7% -34.7% -43.6% · ·
Net Margin 10-point trend, +85.5% -5.2% -137.9% -76.7% -131.3% -79.2% -85.4% -83.5% -62.5% -38.6% -35.9% · ·
Pretax Margin 10-point trend, +76.7% -10.0% -137.5% -259.0% -131.2% -79.0% -95.2% -83.5% -62.0% -37.7% -43.1% · ·
EBITDA Margin 10-point trend, +98.7% -0.42% -120.2% -240.7% -110.1% -59.4% -76.4% -66.7% -37.4% -23.2% -31.5% · ·
ROA 9-point trend, +53.8% -4.3% -46.5% -15.2% -38.4% -26.0% -28.0% -22.3% -16.7% · -9.2% · ·
ROE 9-point trend, -119.7% -34.6% -2246.8% -46.4% -388.1% -59.1% -66.1% -62.7% -32.2% · -15.8% · ·
ROIC 9-point trend, -254.6% -55.8% -548.4% -193.4% -622.8% -53.7% -74.9% -62.1% -25.4% · -15.7% · ·
Liquidität & Solvenz 3
Jährliche Liquidität & Solvenz-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Current Ratio 9-point trend, -31.4% 2.7 2.1 3.5 3.4 4.7 4.4 4.5 4.7 · 4.0 · ·
Quick Ratio 9-point trend, -67.1% 1.1 0.4 0.4 0.6 1.5 1.1 0.8 1.1 · 3.3 · ·
Interest Coverage 8-point trend, +52.8% · · -34.3 -23.6 -8.0 -9.2 -7.3 -8.2 -44.8 -72.8 · ·
Effizienz 3
Jährliche Effizienz-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Asset Turnover 9-point trend, +217.8% 0.8 0.3 0.2 0.3 0.3 0.3 0.3 0.3 · 0.3 · ·
Inventory Turnover 9-point trend, -84.4% 0.3 1.0 1.6 1.1 0.9 0.9 0.9 1.0 · 1.7 · ·
Receivables Turnover 9-point trend, +6.1% 9.2 9.7 7.7 13.0 14.3 11.7 11.4 11.6 · 8.6 · ·
Pro Aktie 5
Jährliche Pro Aktie-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Book Value / Share 9-point trend, -84.4% $1.26 $0.68 $2.66 $0.67 $4.83 $4.04 $5.13 $7.69 · $8.12 · ·
Revenue / Share 8-point trend, +57.7% $5.50 $2.96 $1.96 $3.33 $3.80 · · $4.06 $4.00 $3.49 · ·
Cash Flow / Share 8-point trend, +1115.6% $0.42 $-3.01 $-3.77 $-2.92 $-0.25 · · $-0.62 $0.19 $-0.04 · ·
Cash / Share 9-point trend, -5.4% $1.02 $0.67 $0.77 $0.96 $2.65 $1.62 $1.45 $2.49 · $1.08 · ·
EPS (TTM) 12-point trend, +93.5% $-0.29 $-4.08 $-1.50 $-4.37 $-3.01 $-3.56 $-3.46 $-2.54 $-1.54 $-1.29 $3.17 $-4.43
Wachstumsraten 3
Jährliche Wachstumsraten-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +429.5% 110.5% 60.6% 32.7% -17.0% -33.5% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +758.1% 64.9% 20.9% -9.9% · · · · · · · · ·
Revenue CAGR 5Y 19.9% · · · · · · · · · · ·
Bewertung (TTM) 10
Jährliche Bewertung (TTM)-Daten für TVTX
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +1640.0% $491M $233M $145M $109M $132M $198M $175M $164M $155M $134M $100M $28M
Net Income TTM 12-point trend, +77.0% $-26M $-322M $-111M $-278M $-180M $-169M $-146M $-103M $-60M $-48M $117M $-111M
Market Cap 9-point trend, +384.2% $3.47B $1.52B $678M $1.35B $1.94B $1.42B $612M $937M · $718M · ·
P/E 12-point trend, -4668.7% -131.8 -4.3 -6.0 -4.8 -10.3 -7.7 -4.1 -8.9 -13.7 -14.7 6.1 -2.8
P/S 9-point trend, +31.8% 7.1 6.5 4.7 12.4 14.7 7.2 3.5 5.7 · 5.4 · ·
P/B 9-point trend, +1197.7% 30.3 25.8 3.4 31.6 6.4 6.7 2.8 2.9 · 2.3 · ·
P / Tangible Book 4-point trend, +14179.2% 3618.9 · 7.1 · 12.7 25.3 · · · · · ·
P / Cash Flow 9-point trend, +120.5% 91.9 -6.4 -2.4 -7.3 -131.1 -33.3 -10.5 -37.5 · -449.6 · ·
P / FCF 7-point trend, +99.0% · · -2.4 -7.3 -97.5 -28.8 -10.5 -36.5 · -237.3 · ·
Earnings Yield 12-point trend, +97.9% -0.76% -23.4% -16.7% -20.8% -9.7% -13.1% -24.4% -11.2% -7.3% -6.8% 16.4% -36.2%

Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre

Gewinn- und Verlustrechnung
2025-12-312024-12-312023-12-312022-12-312021-12-31
Umsatz $491M$233M$145M$109M$132M
Betriebsgewinnmarge % -12.8%-138.9%-267.2%-125.7%-71.1%
Nettoergebnis $-26M$-322M$-111M$-278M$-180M
Verwässerte EPS $-0.29$-4.08$-1.50$-4.37$-3.01
Bilanz
2025-12-312024-12-312023-12-312022-12-312021-12-31
Liquiditätsgrad 2.72.13.53.44.7
Quick Ratio 1.10.40.40.61.5
Cashflow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Freier Cashflow $-281M$-186M$-20M

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Institutionelle Eigentümer (13F) 341 Einreicher · $4.3B gesamt · Stand 30. Juni 2026

Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.

Institutionelle Aktivität — Q2 2026 vs. Vorquartal
Neue Positionen Geschlossene Positionen Erhöht Abgenommen Nettoveränderung der Aktien
98 (+52 vs. Vorquartal) 27 (-28 vs. Vorquartal) 108 (+12 vs. Vorquartal) 90 (-2 vs. Vorquartal) +8.8M

Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.

Institution Wert Aktien % der verfolgten 13F Typ
FMR LLC $286.681.837 5.046.327 6,65% Aktien
STATE STREET CORP $241.796.085 4.256.224 5,61% Aktien
VANGUARD CAPITAL MANAGEMENT LLC $233.414.906 4.108.694 5,41% Aktien
BANK OF AMERICA CORP /DE/ $218.865.524 3.852.588 5,08% Aktien
VANGUARD GROUP INC $213.624.812 5.590.809 4,96% Aktien
PERCEPTIVE ADVISORS LLC $213.183.729 3.752.574 4,94% Aktien
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $159.779.000 2.812.514 3,71% Aktien
ADAGE CAPITAL PARTNERS GP, L.L.C. $145.965.114 2.569.356 3,39% Aktien
Rock Springs Capital Management LP $123.792.910 2.179.069 2,87% Aktien
GEODE CAPITAL MANAGEMENT, LLC $115.630.571 2.034.915 2,68% Aktien
Kynam Capital Management, LP $113.620.000 2.000.000 2,64% Aktien
Stephens Investment Management Group LLC $106.536.020 1.875.304 2,47% Aktien
RENAISSANCE TECHNOLOGIES LLC $104.137.218 1.833.079 2,42% Aktien
EMERALD ADVISERS, LLC $90.946.334 1.600.886 2,11% Aktien
ARMISTICE CAPITAL, LLC $89.335.941 1.572.539 2,07% Aktien
TWO SIGMA INVESTMENTS, LP $88.944.917 1.565.656 2,06% Aktien
VANGUARD PORTFOLIO MANAGEMENT LLC $87.579.262 1.541.617 2,03% Aktien
Qube Research & Technologies Ltd $81.989.896 1.443.230 1,90% Aktien
Driehaus Capital Management LLC $81.757.203 1.439.134 1,90% Aktien
BNP PARIBAS FINANCIAL MARKETS $65.726.898 1.156.960 1,52% Aktien
MPM BIOIMPACT LLC $63.782.348 1.122.731 1,48% Aktien
D. E. Shaw & Co., Inc. $62.429.361 1.098.915 1,45% Aktien
EMERALD MUTUAL FUND ADVISERS TRUST $58.629.283 1.032.024 1,36% Aktien
GOLDMAN SACHS GROUP INC $57.488.823 1.011.949 1,33% Aktien
WELLINGTON MANAGEMENT GROUP LLP $56.379.267 992.418 1,31% Aktien
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $46.997.663 827.278 1,09% Aktien
Eversept Partners, LP $45.389.656 798.973 1,05% Aktien
VANGUARD FIDUCIARY TRUST CO $37.598.221 661.824 0,87% Aktien
Ensign Peak Advisors, Inc $33.621.010 591.815 0,78% Aktien
ARMISTICE CAPITAL, LLC $28.405.000 500.000 0,66% Kaufoption
PANAGORA ASSET MANAGEMENT INC $27.878.030 490.724 0,65% Aktien
TWO SIGMA ADVISERS, LP $27.721.355 725.500 0,64% Aktien
Point72 Asset Management, L.P. $27.204.037 478.860 0,63% Aktien
Candriam S.C.A. $26.690.051 470.265 0,62% Aktien
Graham Capital Management, L.P. $25.376.800 446.696 0,59% Aktien
Assenagon Asset Management S.A. $24.275.197 427.305 0,56% Aktien
SCHRODER INVESTMENT MANAGEMENT GROUP $22.086.489 378.842 0,51% Aktien
SUSQUEHANNA INTERNATIONAL GROUP, LLP $21.854.807 384.700 0,51% Verkaufsoption
SUSQUEHANNA INTERNATIONAL GROUP, LLP $21.565.076 379.600 0,50% Kaufoption
Integral Health Asset Management, LLC $21.303.750 375.000 0,49% Aktien
Pictet Asset Management Holding SA $20.067.022 344.510 0,47% Aktien
Artia Global Partners LP $19.260.465 339.033 0,45% Aktien
Capricorn Fund Managers Ltd $18.276.970 321.721 0,42% Aktien
JANE STREET GROUP, LLC $17.332.731 305.100 0,40% Verkaufsoption
JANE STREET GROUP, LLC $17.258.708 303.797 0,40% Aktien
Impax Asset Management Group plc $17.043.000 300.000 0,40% Aktien
Affinity Asset Advisors, LLC $17.043.000 300.000 0,40% Aktien
NEW YORK STATE COMMON RETIREMENT FUND $16.870.127 296.957 0,39% Aktien
Elmind Capital, LP $16.622.606 292.600 0,39% Aktien
FIRST TRUST ADVISORS LP $16.274.815 286.478 0,38% Aktien
LOOMIS SAYLES & CO L P $15.660.870 275.671 0,36% Aktien
Palisades Investment Partners, LLC $15.513.675 273.080 0,36% Aktien
Woodline Partners LP $14.432.808 254.054 0,33% Aktien
ORBIMED ADVISORS LLC $14.372.930 253.000 0,33% Aktien
Universal- Beteiligungs- und Servicegesellschaft mbH $13.896.067 244.606 0,32% Aktien
JACOBS LEVY EQUITY MANAGEMENT, INC $11.676.500 205.536 0,27% Aktien
F/m Investments LLC $10.656.079 187.574 0,25% Aktien
HSBC HOLDINGS PLC $10.436.395 183.707 0,24% Aktien
Caption Management, LLC $10.288.291 181.100 0,24% Kaufoption
Hillsdale Investment Management Inc. $9.538.399 167.900 0,22% Aktien
Palo Alto Investors LP $9.517.095 167.525 0,22% Aktien
Swiss National Bank $9.464.546 166.600 0,22% Aktien
MACKENZIE FINANCIAL CORP $9.462.899 166.571 0,22% Aktien
ALGERT GLOBAL LLC $9.451.593 166.372 0,22% Aktien
SEB Asset Management AB $9.355.055 164.673 0,22% Aktien
Aquatic Capital Management LLC $8.959.505 157.710 0,21% Aktien
Russell Investments Group, Ltd. $8.774.190 154.448 0,20% Aktien
BlackRock, Inc. $8.640.347 152.092 0,20% Aktien
Knott David M Jr $8.367.090 147.282 0,19% Aktien
Voleon Capital Management LP $8.274.661 145.655 0,19% Aktien
NEUBERGER BERMAN GROUP LLC $8.273.979 145.643 0,19% Aktien
JANUS HENDERSON GROUP PLC $7.769.924 261.537 0,18% Aktien
ESSEX INVESTMENT MANAGEMENT CO LLC $7.604.927 133.866 0,18% Aktien
MORGAN STANLEY $7.526.553 132.486 0,17% Aktien
SUSQUEHANNA INTERNATIONAL GROUP, LLP $6.779.194 119.331 0,16% Aktien
Lisanti Capital Growth, LLC $6.760.674 119.005 0,16% Aktien
Informed Momentum Co LLC $6.702.841 117.987 0,16% Aktien
RHUMBLINE ADVISERS $6.461.781 113.744 0,15% Aktien
Apis Capital Advisors, LLC $6.362.720 112.000 0,15% Aktien
CITIGROUP INC $6.242.567 109.885 0,14% Aktien
Squarepoint Ops LLC $6.238.136 109.807 0,14% Aktien
JANE STREET GROUP, LLC $6.044.584 106.400 0,14% Kaufoption
SILVERCREST ASSET MANAGEMENT GROUP LLC $5.920.056 104.208 0,14% Aktien
CITADEL ADVISORS LLC $5.862.792 103.200 0,14% Kaufoption
RICE HALL JAMES & ASSOCIATES, LLC $5.543.122 97.573 0,13% Aktien
ExodusPoint Capital Management, LP $5.535.680 97.442 0,13% Aktien
Calamos Advisors LLC $5.462.395 96.152 0,13% Aktien
SummitTX Capital, L.P. $5.454.783 96.018 0,13% Aktien
ALPS ADVISORS INC $5.339.061 93.981 0,12% Aktien
CITADEL ADVISORS LLC $5.237.882 92.200 0,12% Verkaufsoption
1832 Asset Management L.P. $5.004.961 88.100 0,12% Aktien
HighVista Strategies LLC $4.898.896 86.233 0,11% Aktien
MILLENNIUM MANAGEMENT LLC $4.812.546 84.713 0,11% Aktien
Ishara Investments LP $4.658.420 82.000 0,11% Aktien
SECTOR GAMMA AS $4.544.800 80.000 0,11% Aktien
STATE OF WISCONSIN INVESTMENT BOARD $4.229.391 74.448 0,10% Aktien
Quantinno Capital Management LP $4.025.727 70.863 0,09% Aktien
XTX Topco Ltd $3.631.182 63.918 0,08% Aktien
LOS ANGELES CAPITAL MANAGEMENT LLC $3.623.738 63.787 0,08% Aktien
VANGUARD ASSET MANAGEMENT, Ltd $3.384.513 59.576 0,08% Aktien

Unternehmensinsider 29 Insider · 13 Führungskräfte · 13 Direktoren

Insider Rolle Letzte Aktivität Gehaltene Aktien Käufe 12m Verkäufe 12m Netto 12m
Eric M Dube Chief Executive Officer 5. September 2023 S 242.595 0 0 $0
Christopher R. Cline Chief Financial Officer 5. September 2023 S 50.574 0 0 $0
Laura Clague Chief Financial Officer 11. Mai 2022 S 35.655 0 0 $0
Marc L Panoff Chief Financial Officer 24. Februar 2014 A 221.100 0 0 $0
Neil F. Mcfarlane Chief Operating Officer 16. Mai 2019 S 26.988 0 0 $0
Jula Inrig CHIEF MEDICAL OFFICER 22. Juni 2026 G 112.770 0 0 $0
Peter Heerma Chief Commercial Officer 3. Oktober 2023 S 80.257 0 0 $0
William E. Rote Senior Vice President, R&D 5. September 2023 S 61.173 0 0 $0
Sandra Calvin SVP, Chief Accounting Officer 11. Mai 2023 S 42.247 0 0 $0
Noah L. Rosenberg Chief Medical Officer 17. August 2021 S 47.614 0 0 $0
Alvin Shih EVP of Research & Development 1. September 2016 S 158.334 0 0 $0
VALEUR JENSEN MARGARET E General Counsel 1. Februar 2016 A 100.000 0 0 $0
Horacio Plotkin Chief Medical Officer 12. Dezember 2014 S 91.767 0 0 $0
Roy D. Baynes Direktor 12. Juni 2026 M 41.500 0 1 $-225.000
Timothy Coughlin Direktor 12. Juni 2026 M 56.250 0 3 $-1.272.582
LYONS GARY A Direktor 19. Mai 2026 A 61.500 0 1 $-328.560
Sandra Poole Direktor 17. Mai 2023 A 17.000 0 0 $0
Suzanne Louise Bruhn Direktor 17. Mai 2023 A 15.750 0 0 $0
Jeffery A. Meckler Direktor 17. Mai 2023 A 74.500 0 0 $0
John A Orwin Direktor 17. Mai 2023 A 22.375 0 0 $0
Ron Squarer Direktor 17. Mai 2023 A 22.375 0 0 $0
Steve Aselage Direktor 11. Mai 2022 S 146.919 0 0 $0
John W Kozarich Direktor 8. Mai 2019 A 29.000 0 0 $0
Steven Gary Richardson Direktor 21. November 2014 P 129.165 0 0 $0
Jeffrey Paley Direktor 14. August 2014 S 51.665 0 0 $0
Ruth Williams Brinkley 19. Mai 2026 A 29.750 0 0 $0
Elizabeth E Reed 4. Mai 2026 M 105.211 0 16 $-4.928.520
Cornelius E Golding 18. Mai 2016 A 29.000 0 0 $0
Martin Shkreli 12. September 2014 J 1.765.168 0 0 $0

Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten

Aktivisten & 5%+-Eigentümer 2 Beteiligungen

Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.

Anmelder Eingereicht Beteiligung Status Zweck Einreichung
Opaleye L.P ×3 Einreichungen 5. Juni 2015 Erste Einreichung SEC
MSMB Capital Management LP, MSMB Capital Management LLC, MSMB Healthcare LP, MSMB Healthcare Investors LLC, MSMB Healthcare Management LLC, Martin Shkreli ×2 Einreichungen 19. Februar 2013 Erste Einreichung SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF-Besitz Gehalten von 53 ETFs

Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.

Fonds Gewicht Anteile Stand Quelle
LFSC · RBB Fund, Inc. 7,67% 170.714 NS 31. Mai 2026 N-PORT
PJP · Invesco Exchange-Traded Fund Trust 3,52% 290.649 SH 8. August 2026 Täglich
SBIO · ALPS ETF Trust 2,77% 95.051 NS 31. Mai 2026 N-PORT
PTH · Invesco Exchange-Traded Fund Trust 2,28% 91.638 SH 8. August 2026 Täglich
SPIT · RBB Fund, Inc. 2,06% 14.023 NS 30. April 2026 N-PORT
BBP · ETFis Series Trust I 1,93% 27.170 NS 30. April 2026 N-PORT
LABU · Direxion Shares ETF Trust 1,33% 164.067 NS 30. April 2026 N-PORT
MMSC · First Trust Exchange-Traded Fund VI… 1,06% 11.744 NS 31. Mai 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0,81% 37.788 SH 8. August 2026 Täglich
BRNY · EA Series Trust 0,64% 84.570 NS 30. April 2026 N-PORT
FYC · First Trust Exchange-Traded AlphaDE… 0,63% 157.219 NS 30. April 2026 N-PORT
DWAS · Invesco Exchange-Traded Fund Trust … 0,43% 31.899 SH 8. August 2026 Täglich
IBB · iShares Trust 0,43% 662.786 SH 8. August 2026 Täglich
IBBQ · Invesco Exchange-Traded Fund Trust … 0,39% 5.059 SH 8. August 2026 Täglich
IWO · iShares Trust 0,34% 809.244 SH 8. August 2026 Täglich
VTWG · VANGUARD SCOTTSDALE FUNDS 0,30% 95.695 SH 8. August 2026 Täglich
OASC · Unified Series Trust 0,28% 4.971 NS 31. Mai 2026 N-PORT
AFSM · First Trust Exchange-Traded Fund VI… 0,28% 5.759 NS 31. Mai 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0,26% 54.435 NS 31. Mai 2026 N-PORT
ESSC · Strategy Shares 0,25% 1.513 NS 30. April 2026 N-PORT
FYX · First Trust Exchange-Traded AlphaDE… 0,24% 70.102 NS 30. April 2026 N-PORT
BIB · ProShares Trust 0,22% 3.409 NS 31. Mai 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0,19% 32.277 NS 30. April 2026 N-PORT
ISCG · iShares Trust 0,18% 29.119 SH 8. August 2026 Täglich
IWM · iShares Trust 0,18% 2.265.933 SH 8. August 2026 Täglich
BKSE · BNY Mellon ETF Trust 0,17% 3.185 NS 30. April 2026 N-PORT
FSCC · Federated Hermes ETF Trust 0,15% 8.833 NS 31. Mai 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0,15% 514.614 SH 8. August 2026 Täglich
PRFZ · Invesco Exchange-Traded Fund Trust 0,15% 70.504 SH 8. August 2026 Täglich
FAD · First Trust Exchange-Traded AlphaDE… 0,13% 14.646 NS 30. April 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0,11% 37.027 SH 8. August 2026 Täglich
RSSL · Global X Funds 0,11% 35.731 NS 30. April 2026 N-PORT
ITWO · ProShares Trust 0,10% 3.881 NS 31. Mai 2026 N-PORT
FBCG · FIDELITY COVINGTON TRUST 0,09% 133.749 NS 30. April 2026 N-PORT
ISCB · iShares Trust 0,09% 4.157 SH 8. August 2026 Täglich
SCHA · SCHWAB STRATEGIC TRUST 0,09% 431.230 NS 31. Mai 2026 N-PORT
ESML · iShares Trust 0,09% 39.850 SH 8. August 2026 Täglich
VHT · VANGUARD WORLD FUND 0,07% 249.426 SH 8. August 2026 Täglich
SMLF · iShares Trust 0,07% 46.167 SH 8. August 2026 Täglich
VXF · VANGUARD INDEX FUNDS 0,06% 1.066.102 SH 8. August 2026 Täglich
UWM · ProShares Trust 0,06% 3.036 NS 31. Mai 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0,06% 38.888 NS 30. April 2026 N-PORT
WSML · iShares Trust 0,05% 4.868 SH 8. August 2026 Täglich
URTY · ProShares Trust 0,04% 3.073 NS 31. Mai 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,02% 3.488 NS 31. Mai 2026 N-PORT
HDG · ProShares Trust 0,02% 77 NS 31. Mai 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0,01% 26.832 NS 31. Mai 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0,01% 2.948.502 SH 8. August 2026 Täglich
VTHR · VANGUARD SCOTTSDALE FUNDS 0,01% 7.348 SH 8. August 2026 Täglich
ITOT · iShares Trust 0,01% 124.087 SH 8. August 2026 Täglich