PTCT PTC Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · Auf SEC EDGAR ansehen ↗
$72,62
Kurs · Aug 19, 2026
Fundamentaldaten per Jul 30, 2026

Über PTC Therapeutics, Inc. - Common Stock Unternehmensübersicht von Wikipedia

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

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PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

In September 2009, PTC entered into an agreement with Roche for the development of orally bioavailable small molecules for central nervous system diseases. PTC acquired the Bio-e platform in 2019.

Products

In 2017, PTC acquired Emflaza (deflazacort) from Marathon Pharmaceuticals. PTC also owns Translarna, (Ataluren) marketed for nonsense mutation Duchenne muscular dystrophy. Together, the two products generated revenues of 174 million dollars and 260 million dollars in 2017 and 2018 respectively.

PTC has the commercialization rights for WAYLIVRA (volanesorsen) in Latin America.

In 2018, PTC acquired Agilis Biotherapeutics and a gene therapy candidate, GT-AADC, with its compelling clinical data in treating aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency is a rare CNS disorder arising from reductions in the enzyme AADC that result from mutations in the dopa decarboxylase (DDC) gene. As of 2024, the AAV based treatment for AADC deficiency has been approved by the FDA and commercialized in the United States as Kebilidi. It is the first FDA-approved gene therapy treatment for AADC deficiency. This same product was granted EMA approval for use in the European Union under the name Upstaza.

Pipeline

In 2020, PTC acquired Censa Pharmaceuticals, Inc., a biopharmaceutical company focused on the development of CNSA-001 (sepiapterin), a clinical-stage investigational therapy for orphan metabolic diseases, including phenylketonuria (PKU) and other diseases associated with defects in the tetrahydrobiopterin (BH4) biochemical pathways diagnosed at birth.

In 2020, PTC announced the FDA approval of Evrysdi (risdiplam) for the treatment of spinal muscular atrophy (SMA) in adults and children 2 months and older.

In 2024, Novartis has committed $1 billion upfront in a licensing deal with PTC Therapeutics for an experimental treatment for Huntington’s disease, with the potential for an additional $1.9 billion tied to achieving specific development, regulatory, and commercial milestones. PTC Therapeutics’ therapy, known as PTC518, is an oral medication designed to reduce the production of the mutant protein linked to the genetic mutation responsible for the disease. This mutant protein is believed to contribute to neuronal death, driving disease progression. In June, interim data from a Phase 2 trial indicated that PTC518 successfully lowered levels of the mutant protein in both blood and cerebrospinal fluid.

Quelle: Wikipedia (Englisch), CC BY-SA 4.0 · Auf Wikipedia ansehen ↗

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PTCT Aktien-Snapshot Kurs, Marktkapitalisierung, P/E, EPS, ROE, Schulden/Eigenkapital, 52-Wochen-Spanne

Kurs
$72.62
Marktkapitalisierung
$5.92B
P/E (TTM)
9.3
EPS (TTM)
$7.78
Umsatz (TTM)
$1.73B
Dividendenrendite
ROE
-331.5%
Verschuldungsgrad
-1.4
52W-Spanne
$48 – $91

PTCT Aktienkurs-Chart Täglich OHLCV mit technischen Indikatoren — Schwenken, Zoom und Ansicht anpassen

10-Jahres-Performance Umsatz-, Nettoergebnis-, Margen- und EPS-Trends

Umsatz & Nettoergebnis $1.73B
10-point trend, +1992.6%
2016-12-31 2025-12-31
EPS $7.78
7-point trend, +282.2%
2019-12-31 2025-12-31
Freier Cashflow $702M
9-point trend, +766.7%
2016-12-31 2025-12-31
Margen 39.4%

Bewertung P/E-, P/S-, P/B-, EV/EBITDA-Verhältnisse — ist die Aktie teuer oder günstig?

Kennzahl
5-Jahres-Trend
PTCT
Peer-Median
P/E (TTM)
5-point trend, +282.1%
9.3
37.2
P/S (TTM) (K/V (TTM))
5-point trend, -68.0%
3.4
9.9
P/B (K/B)
5-point trend, -441.5%
-28.8
8.3
EV / EBITDA
5-point trend, +156.1%
4.7
Price / FCF (Kurs / FCF)
5-point trend, +143.9%
8.4

Rentabilität Brutto-, Betriebs- und Nettomargen; ROE, ROA, ROIC

Kennzahl
5-Jahres-Trend
PTCT
Peer-Median
Operating Margin (Betriebsgewinnmarge)
5-point trend, +144.2%
50.1%
Net Profit Margin (Nettogewinnmarge)
5-point trend, +134.3%
39.4%
-15.1%
ROA
5-point trend, +229.7%
29.7%
-23.3%
ROE
5-point trend, -275.6%
-331.5%
-30.6%
ROIC
5-point trend, +1860.3%
1044.7%

Finanzielle Gesundheit Verschuldung, Liquidität, Solvenz — Bilanzstärke

Kennzahl
5-Jahres-Trend
PTCT
Peer-Median
Debt / Equity (Fremdkapital / Eigenkapital)
5-point trend, -317.7%
-1.4
Current Ratio (Liquiditätsgrad)
5-point trend, -47.1%
2.3
6.3
Quick Ratio
5-point trend, -48.1%
2.2

Wachstum Umsatz-, EPS- und Nettoergebniswachstum: YoY, 3-Jahres-CAGR, 5-Jahres-CAGR

Kennzahl
5-Jahres-Trend
PTCT
Peer-Median
Revenue YoY (Umsatz YoY)
5-point trend, +221.3%
114.5%
Revenue CAGR 3Y (Umsatz CAGR 3J)
5-point trend, +221.3%
35.3%
Revenue CAGR 5Y (Umsatz CAGR 5J)
5-point trend, +221.3%
35.4%

Kennzahlen pro Aktie EPS, Buchwert pro Aktie, Cashflow pro Aktie, Dividende pro Aktie

Kennzahl
5-Jahres-Trend
PTCT
Peer-Median
EPS (Diluted) (EPS (Verwässert))
5-point trend, +204.7%
$7.78

Kapitaleffizienz Umsatz pro Vermögenswert, Lagerumschlag, Forderungsumschlag

Kennzahl
5-Jahres-Trend
PTCT
Peer-Median

PTCT Analysten-Konsens Bullische und bärische Analystenmeinungen, 12-Monats-Kursziel, Aufwärtspotenzial

KAUF 21 Analysten
  • Starker Kauf 6 28,6%
  • Kauf 11 52,4%
  • Halten 3 14,3%
  • Verkauf 1 4,8%
  • Starker Verkauf 0 0,0%

12-Monats-Kursziel

14 Analysten · 2026-08-13
Median-Ziel $98.00 +34,9%
Mittelwert-Ziel $97.86 +34,8%

Ergebnisverlauf EPS Ist vs. Schätzung, Überraschung %, Beat-Rate, nächstes Ergebnisdatum

Durchschn. Überraschung
1.9%
Zeitraum EPS Actual EPS est. Überraschung
30. Juni 2026 $0.92 $0.43 0.49%
31. März 2026 $-0.03 $-0.48 0.45%
31. Dezember 2025 $-1.67 $0.04 -1.7%
30. September 2025 $0.20 $-1.40 1.6%
30. Juni 2025 $-0.83 $-1.08 0.25%
31. März 2025 $10.04 $-0.22 10.3%

Peer-Vergleich (GICS-Subbranche) Wichtige Kennzahlen im Vergleich zu Branchenkollegen

Ticker Marktkapitalisierung P/E Umsatz Vj. Nettomarge ROE Bruttogewinnmarge
PTCT $6.19B 9.8 114.5% 39.4% -331.5%
MIRM $4.10B -168.1 54.7% -4.5% -8.2%
COGT $5.72B -16.4 -83.1%
DNTH $1.78B -9.8 -67.3% -7973.3% -40.8%
ERAS $1.06B -8.5 -35.7%
CAI $7.62B -8.4 97.0% -8.4% -13.2%
TVTX $3.47B -131.8 110.5% -5.2% -34.6%
ACAD $4.55B 11.6 11.9% 36.5% 38.1%
DYN $3.23B -5.6 -57.8%
PBLS
CELC $4.81B -26.3 -244.3%

Vollständige Fundamentaldaten Alle Kennzahlen nach Jahr — Gewinn- und Verlustrechnung, Bilanz, Cashflow

Gewinn- und Verlustrechnung 15
Jährliche Gewinn- und Verlustrechnung-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +6755.4% $1.73B $807M $938M $699M $539M $381M $307M $265M $194M $83M $37M $25M
Cost of Revenue 5-point trend, +12135000.00 · · · · · · $12M $13M $5M $0 $0 ·
R&D Expense 12-point trend, +470.2% $455M $534M $667M $651M $541M $478M $257M $172M $117M $118M $122M $80M
SG&A Expense 12-point trend, +674.5% $347M $301M $333M $326M $286M $245M $203M $154M $121M $97M $82M $45M
Operating Expenses 12-point trend, +592.9% $864M $1.11B $1.38B $1.15B $913M $813M $548M $380M $259M $215M $204M $125M
Operating Income 12-point trend, +972.1% $867M $-303M $-440M $-447M $-374M $-432M $-241M $-116M $-64M $-132M $-167M $-99M
Other Non-op 12-point trend, -8391.1% $-18M $7M $10M $-49M $-58M $85M $14M $129.0K $-1M $-1M $-465.0K $-213.0K
Pretax Income 12-point trend, +807.6% $697M $-363M $-696M $-587M $-518M $-403M $-240M $-128M $-78M $-142M $-170M $-98M
Income Tax 12-point trend, +397.8% $14M $176.0K $-70M $-28M $6M $35M $12M $-29.0K $1M $569.0K $485.0K $-5M
Net Income 12-point trend, +828.1% $683M $-363M $-627M $-559M $-524M $-438M $-252M $-128M $-79M $-142M $-170M $-94M
EPS (Basic) 10-point trend, +388.9% $8.58 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 $-2.75 $-2.02 · · $-2.97
EPS (Diluted) 8-point trend, +362.0% $7.78 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 · · · · $-2.97
Shares (Basic) 8-point trend, +152.0% 79,534,290 76,845,055 74,838,292 71,728,634 70,466,393 66,027,908 58,863,185 · · · · 31,565,310
Shares (Diluted) 8-point trend, +179.8% 88,311,494 76,845,055 74,838,292 71,728,634 70,466,393 66,027,908 58,863,185 · · · · 31,565,310
EBITDA 11-point trend, +1011.1% $906M $-227M $-203M · $-310M $-388M $-209M $-90M $-47M $-132M $-167M $-99M
Bilanz 27
Jährliche Bilanz-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +1879.3% $985M $780M $594M $280M $190M $209M $288M $169M $112M $58M $58M $50M
Short-term Investments 12-point trend, +261.9% $961M $360M $283M $131M $584M $895M $399M $58M $79M $173M $281M $265M
Receivables 12-point trend, +3986.0% $182M $159M $161M $156M $110M $70M $56M $68M $40M $25M $11M $4M
Inventory 10-point trend, +79647000.00 $80M $23M $31M $22M $16M $19M $19M $16M $11M $0 · ·
Prepaid Expense 12-point trend, +1632.5% $67M $44M $150M $106M $55M $39M $18M $9M $7M $5M $6M $4M
Current Assets 12-point trend, +602.8% $2.27B $1.37B $1.22B $694M $954M $1.23B $779M $321M $249M $261M $356M $324M
PP&E (Net) 12-point trend, +504.6% $55M $61M $87M $73M $53M $34M $22M $13M $8M $7M $9M $9M
PP&E (Gross) 12-point trend, +200.4% $102M $94M $138M $110M $80M $52M $33M $20M $41M $38M $37M $34M
Accum. Depreciation 12-point trend, +88.6% $47M $33M $51M $37M $27M $18M $12M $7M $33M $31M $28M $25M
Goodwill 9-point trend, +82341000.00 $82M $82M $82M $82M $82M $82M $82M $82M $0 · · ·
Intangibles 10-point trend, +388753000.00 $389M $119M $379M $706M $725M $715M $710M $701M $133M $0 · ·
Total Assets 12-point trend, +769.9% $2.90B $1.71B $1.90B $1.71B $1.94B $2.21B $1.62B $1.12B $392M $269M $365M $333M
Accounts Payable 12-point trend, +1001.9% $45M $17M $6M $27M $23M $19M $10M $6M $15M $6M $6M $4M
Current Liabilities 12-point trend, +2882.1% $968M $581M $603M $406M $509M $277M $236M $167M $82M $50M $45M $32M
Capital Leases 7-point trend, +937.7% $94M $75M $98M $101M $74M $79M $9M · · · · ·
Deferred Tax 7-point trend, +55905000.00 · · $56M $103M $137M $137M $131M $122M $0 · · ·
Other Non-current Liabilities 11-point trend, +501.8% $14M $21M $141.0K $3M · $1M $141.0K $58.0K $243.0K $335.0K $2M $2M
Total Liabilities 12-point trend, +8832.1% $3.10B $2.80B $2.71B $2.05B $1.94B $1.73B $1.03B $768M $235M $150M $139M $35M
Long-term Debt 4-point trend, +197.6% · · · · $431M · $314M $153M $145M · · ·
Total Debt 10-point trend, +203.0% $287M $285M $284M · $431M $309M $314M $153M $145M $98M $95M ·
Common Stock 12-point trend, +142.4% $80.0K $77.0K $75.0K $72.0K $71.0K $70.0K $62.0K $51.0K $42.0K $34.0K $34.0K $33.0K
Paid-in Capital 12-point trend, +280.8% $2.75B $2.57B $2.47B $2.31B $2.12B $2.17B $1.80B $1.29B $967M $856M $820M $722M
Retained Earnings 12-point trend, -601.5% $-2.96B $-3.65B $-3.28B $-2.66B $-2.10B $-1.63B $-1.19B $-939M $-814M $-735M $-593M $-423M
AOCI 12-point trend, +1524.8% $11M $-26M $-1M $5M $-24M $-61M $-11M $1M $4M $-1M $-1M $-737.0K
Stockholders' Equity 12-point trend, -168.8% $-205M $-1.10B $-819M $-347M $1M $482M $594M $351M $156M $120M $226M $298M
Liabilities + Equity 12-point trend, +769.9% $2.90B $1.71B $1.90B $1.71B $1.94B $2.21B $1.62B $1.12B $392M $269M $365M $333M
Shares Outstanding 12-point trend, +147.7% 81,474,366 77,704,188 75,708,889 73,104,692 70,828,226 69,718,096 61,935,870 50,606,147 41,612,395 34,169,410 33,916,559 32,898,392
Cashflow 16
Jährliche Cashflow-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
D&A 11-point trend, +1249.6% $39M $76M $237M $129M $64M $43M $32M $26M $18M $3M $3M ·
Stock-based Comp 12-point trend, +286.1% $75M $75M $102M $110M $104M $70M $42M $33M $31M $35M $34M $19M
Deferred Tax 12-point trend, -3000.00 $-3.0K $-56M $-47M $-34M $377.0K $6M $9M $0 $199.0K $-199.0K $0 $0
Amort. of Intangibles 11-point trend, +24742000.00 $25M $61M $223M $117M $55M $37M $28M $23M $15M $0 $0 ·
Restructuring · · · · · · · · $0 · · ·
Other Non-cash 8-point trend, -513.8% $-85M $161M $177M · $105M $124M $70M $41M $20M · · ·
Operating Cash Flow 12-point trend, +1341.7% $711M $-108M $-158M $-357M $-251M $-194M $-99M $-28M $-10M $-104M $-124M $-57M
CapEx 12-point trend, +90.0% $9M $7M $28M $32M $28M $18M $14M $7M $3M $2M $3M $5M
Investing Cash Flow 12-point trend, -493.8% $-862M $44M $-177M $290M $219M $-562M $-387M $-43M $13M $104M $-21M $-145M
Net Debt Issued 2-point trend, +100.0% · · · · · · · · · $0 · $-49.0K
Stock Issued 7-point trend, -88.1% · · · · · $28M $324M $118M $0 $0 $0 $236M
Net Stock Activity 5-point trend, -88.1% · · · · · $28M $324M $118M · $0 · $236M
Financing Cash Flow 12-point trend, +39.6% $331M $256M $646M $168M $21M $669M $613M $132M $44M $968.0K $154M $237M
Net Change in Cash 12-point trend, +491.3% $203M $185M $314M $99M $-19M $-79M $126M $58M $53M $299.0K $8M $34M
Taxes Paid 12-point trend, +36854000.00 $37M $18M $14M $5M $8M $26M $2M $2M $1M $943.0K $111.0K $0
Free Cash Flow 11-point trend, +1233.9% $702M $-114M $-187M · $-280M $-212M $-112M $-35M $-13M $-105M $-127M $-62M
Rentabilität 7
Jährliche Rentabilität-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +112.7% 50.1% -37.5% -46.9% · -69.5% -113.4% -78.6% -43.7% -33.1% -159.7% -454.6% -393.8%
Net Margin 11-point trend, +110.6% 39.4% -45.0% -66.8% · -97.3% -115.1% -82.0% -48.4% -40.6% -171.8% -463.6% -371.4%
Pretax Margin 11-point trend, +110.3% 40.2% -45.0% -74.2% · -96.2% -105.8% -78.2% -48.4% -40.0% -171.1% -462.3% -390.0%
EBITDA Margin 11-point trend, +113.3% 52.3% -28.1% -21.6% · -57.6% -102.0% -68.1% -33.8% -24.0% -159.7% -454.6% -393.8%
ROA 11-point trend, +176.7% 29.7% -20.2% -34.8% · -25.3% -22.9% -18.3% -17.0% -23.9% -44.8% -48.6% -38.6%
ROE 11-point trend, -669.1% -331.5% 33.8% 84.1% · -985.1% -88.3% -40.0% -34.8% -57.2% -82.2% -65.0% -43.1%
ROIC 11-point trend, +3393.6% 1044.7% 37.2% 74.0% · -87.4% -59.4% -27.8% -23.0% -21.7% -60.9% -52.3% -31.7%
Liquidität & Solvenz 4
Jährliche Liquidität & Solvenz-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -76.4% 2.3 2.4 2.0 · 1.9 4.4 3.3 1.9 3.0 5.3 7.8 10.0
Quick Ratio 11-point trend, -77.7% 2.2 2.2 1.7 · 1.7 4.2 3.1 1.8 2.8 5.2 7.7 9.8
Debt / Equity 10-point trend, -433.5% -1.4 -0.3 -0.3 · 300.0 0.6 0.5 0.4 0.9 0.8 0.4 ·
LT Debt / Equity 9-point trend, -162.1% · -0.3 -0.3 · 196.0 0.6 0.5 0.4 0.9 0.8 0.4 ·
Effizienz 3
Jährliche Effizienz-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, +622.2% 0.8 0.4 0.5 · 0.3 0.2 0.2 0.4 0.6 0.3 0.1 0.1
Inventory Turnover 2-point trend, -19.5% · · · · · · 0.7 · 0.9 · · ·
Receivables Turnover 11-point trend, +8.9% 10.2 5.1 5.9 · 6.0 6.1 5.0 4.9 6.0 4.6 4.7 9.3
Pro Aktie 5
Jährliche Pro Aktie-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, -127.8% $-2.52 $-14.13 $-10.81 · $0.02 $6.91 $9.60 $6.93 $3.76 $3.50 $6.66 $9.07
Revenue / Share 5-point trend, +2350.3% $19.60 $10.50 $12.53 · $7.64 · · · · · · $0.80
Cash Flow / Share 5-point trend, +543.8% $8.05 $-1.40 $-2.12 · $-3.57 · · · · · · $-1.81
Cash / Share 11-point trend, +699.2% $12.09 $10.03 $7.85 · $2.68 $3.00 $4.65 $3.35 $2.69 $1.71 $1.71 $1.51
EPS (TTM) 12-point trend, +362.0% $7.78 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 $-3.21 $-3.21 $-3.21 $-3.21 $-2.97
Wachstumsraten 3
Jährliche Wachstumsraten-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +176.3% 114.5% -14.0% 34.2% 29.8% 41.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +0.7% 35.3% 14.4% 35.0% · · · · · · · · ·
Revenue CAGR 5Y 35.4% · · · · · · · · · · ·
Bewertung (TTM) 13
Jährliche Bewertung (TTM)-Daten für PTCT
Kennzahl Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +6755.4% $1.73B $807M $938M $699M $539M $381M $307M $265M $194M $83M $37M $25M
Net Income TTM 12-point trend, +828.1% $683M $-363M $-627M $-559M $-524M $-438M $-252M $-128M $-79M $-142M $-170M $-94M
Market Cap 11-point trend, +263.4% $6.19B $3.51B $2.09B · $2.82B $4.25B $2.97B $1.74B $694M $373M $1.10B $1.70B
Enterprise Value 10-point trend, +430.1% $4.53B $2.65B $1.49B · $2.48B $3.46B $2.60B $1.66B $648M $239M $855M ·
P/E 12-point trend, +156.0% 9.8 -9.5 -3.3 -4.9 -5.4 -9.2 -11.2 -10.7 -5.2 -3.4 -10.1 -17.4
P/S 11-point trend, -94.7% 3.6 4.3 2.2 · 5.2 11.2 9.7 6.6 3.6 4.5 29.9 67.5
P/B 11-point trend, -628.2% -30.1 -3.2 -2.5 · 1961.8 8.8 5.0 5.0 4.4 3.1 4.9 5.7
P / Cash Flow 11-point trend, +129.3% 8.7 -32.6 -13.2 · -11.2 -21.9 -30.2 -62.8 -69.0 -3.6 -8.8 -29.7
P / FCF 11-point trend, +132.0% 8.8 -30.7 -11.2 · -10.1 -20.1 -26.5 -50.0 -52.7 -3.5 -8.6 -27.5
EV / EBITDA 10-point trend, +197.8% 5.0 -11.7 -7.4 · -8.0 -8.9 -12.5 -18.6 -13.9 -1.8 -5.1 ·
EV / FCF 10-point trend, +195.9% 6.5 -23.2 -8.0 · -8.9 -16.3 -23.2 -47.9 -49.2 -2.3 -6.7 ·
EV / Revenue 10-point trend, -88.7% 2.6 3.3 1.6 · 4.6 9.1 8.5 6.3 3.3 2.9 23.2 ·
Earnings Yield 12-point trend, +278.4% 10.2% -10.5% -30.4% -20.4% -18.6% -10.9% -8.9% -9.3% -19.2% -29.4% -9.9% -5.7%

Finanzberichte Gewinn- und Verlustrechnung, Bilanz, Cashflow — jährlich, letzte 5 Jahre

Gewinn- und Verlustrechnung
2025-12-312024-12-312023-12-312022-12-312021-12-31
Umsatz $1.73B$807M$938M$699M$539M
Betriebsgewinnmarge % 50.1%-37.5%-46.9%-69.5%
Nettoergebnis $683M$-363M$-627M$-559M$-524M
Verwässerte EPS $7.78$-4.73$-8.37$-7.79$-7.43
Bilanz
2025-12-312024-12-312023-12-312022-12-312021-12-31
Fremdkapital / Eigenkapital -1.4-0.3-0.3300.0
Liquiditätsgrad 2.32.42.01.9
Quick Ratio 2.22.21.71.7
Cashflow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Freier Cashflow $702M$-114M$-187M$-280M

Handelssignale Aktuelle Kauf-/Verkaufssignale mit Einstiegspreis und Risiko-Ertrags-Verhältnis

Meine Kennzahlen Ihre persönliche Watchlist — ausgewählte Zeilen aus den vollständigen Fundamentaldaten

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Wählen Sie die Kennzahlen, die für Sie wichtig sind — klicken Sie auf das ➕ neben jeder Zeile in den vollständigen Fundamentaldaten oben.

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Institutionelle Eigentümer (13F) 403 Einreicher · $5.4B gesamt · Stand 30. Juni 2026

Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.

Institutionelle Aktivität — Q2 2026 vs. Vorquartal
Neue Positionen Geschlossene Positionen Erhöht Abgenommen Nettoveränderung der Aktien
83 (+22 vs. Vorquartal) 43 (-9 vs. Vorquartal) 133 (-4 vs. Vorquartal) 109 (+6 vs. Vorquartal) +2.1M

Verglichen mit Q1 2026. SEC-Formular 13F-Einreichungen sind innerhalb von 45 Tagen nach Quartalsende fällig, zuzüglich einer kurzen Pufferzeit für verspätete Einreicher — Quartale, die noch in diesem Fenster liegen, werden zugunsten des letzten vollständig berichteten Paares übersprungen.

Institution Wert Aktien % der verfolgten 13F Typ
RTW INVESTMENTS, LP $631.875.072 7.746.415 11,70% Aktien
JANUS HENDERSON GROUP PLC $479.178.655 7.034.622 8,87% Aktien
VANGUARD PORTFOLIO MANAGEMENT LLC $401.986.014 4.928.111 7,45% Aktien
STATE STREET CORP $375.136.515 4.598.952 6,95% Aktien
VANGUARD CAPITAL MANAGEMENT LLC $305.000.589 3.739.127 5,65% Aktien
WELLINGTON MANAGEMENT GROUP LLP $292.435.873 3.585.091 5,42% Aktien
WESTFIELD CAPITAL MANAGEMENT CO LP $159.563.645 1.956.156 2,96% Aktien
GEODE CAPITAL MANAGEMENT, LLC $155.132.041 1.901.417 2,87% Aktien
Hood River Capital Management LLC $141.818.662 1.738.613 2,63% Aktien
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC $140.519.660 1.722.688 2,60% Aktien
TANG CAPITAL MANAGEMENT LLC $122.355.000 1.500.000 2,27% Aktien
Driehaus Capital Management LLC $117.469.528 1.440.107 2,18% Aktien
Jefferies Financial Group Inc. $110.693.916 1.357.042 2,05% Aktien
FULLER & THALER ASSET MANAGEMENT, INC. $94.361.749 1.156.819 1,75% Aktien
Pictet Asset Management Holding SA $93.629.635 1.147.844 1,73% Aktien
ARMISTICE CAPITAL, LLC $87.393.690 1.071.395 1,62% Aktien
Blue Sparrow, LLC /DE $85.705.599 1.050.700 1,59% Aktien
D. E. Shaw & Co., Inc. $77.478.857 949.845 1,44% Aktien
Palo Alto Investors LP $74.950.268 918.846 1,39% Aktien
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $64.449.436 790.112 1,19% Aktien
RENAISSANCE TECHNOLOGIES LLC $59.015.895 723.500 1,09% Aktien
Boston Partners $57.080.953 699.871 1,06% Aktien
FMR LLC $56.956.987 698.259 1,05% Aktien
BANK OF AMERICA CORP /DE/ $56.350.840 690.828 1,04% Aktien
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $53.377.940 654.382 0,99% Aktien
DIMENSIONAL FUND ADVISORS LP $51.486.821 631.199 0,95% Aktien
VANGUARD FIDUCIARY TRUST CO $47.953.943 587.887 0,89% Aktien
Ensign Peak Advisors, Inc $41.442.128 508.056 0,77% Aktien
AMERICAN CENTURY COMPANIES INC $40.866.277 500.995 0,76% Aktien
MANUFACTURERS LIFE INSURANCE COMPANY, THE $36.050.432 441.957 0,67% Aktien
Parkman Healthcare Partners LLC $35.539.315 435.691 0,66% Aktien
LOOMIS SAYLES & CO L P $35.387.921 433.835 0,66% Aktien
Defilade Capital Management, L.P. $35.376.827 433.699 0,66% Aktien
GOLDMAN SACHS GROUP INC $34.153.522 418.702 0,63% Aktien
SUSQUEHANNA INTERNATIONAL GROUP, LLP $32.274.149 395.662 0,60% Aktien
BNP PARIBAS FINANCIAL MARKETS $30.892.190 378.720 0,57% Aktien
Qube Research & Technologies Ltd $25.398.777 311.374 0,47% Aktien
ARMISTICE CAPITAL, LLC $24.471.000 300.000 0,45% Kaufoption
Public Sector Pension Investment Board $23.249.326 285.023 0,43% Aktien
SEGALL BRYANT & HAMILL, LLC $22.165.424 271.735 0,41% Aktien
CITADEL ADVISORS LLC $20.338.011 249.332 0,38% Aktien
MORGAN STANLEY $18.990.210 232.808 0,35% Aktien
Boxer Capital Management, LLC $16.314.000 200.000 0,30% Aktien
RHUMBLINE ADVISERS $15.718.994 192.706 0,29% Aktien
AMERIPRISE FINANCIAL INC $13.904.178 170.457 0,26% Aktien
PRUDENTIAL FINANCIAL INC $13.746.176 168.520 0,25% Aktien
BlackRock, Inc. $13.589.562 166.600 0,25% Aktien
Rock Springs Capital Management LP $13.238.648 162.298 0,25% Aktien
Hudson Bay Capital Management LP $13.033.091 159.778 0,24% Aktien
Russell Investments Group, Ltd. $12.687.724 155.544 0,23% Aktien
Schonfeld Strategic Advisors LLC $12.025.457 147.425 0,22% Aktien
MARSHALL WACE, LLP $11.724.301 143.733 0,22% Aktien
Swiss National Bank $11.539.300 141.465 0,21% Aktien
Universal- Beteiligungs- und Servicegesellschaft mbH $11.063.583 135.633 0,20% Aktien
Legal & General Group Plc $10.362.979 127.044 0,19% Aktien
CITIGROUP INC $9.272.143 113.671 0,17% Aktien
FIRST TRUST ADVISORS LP $9.246.285 113.354 0,17% Aktien
Longaeva Partners L.P. $9.119.771 111.803 0,17% Aktien
JUPITER ASSET MANAGEMENT LTD $8.927.184 109.442 0,17% Aktien
SCHRODER INVESTMENT MANAGEMENT GROUP $8.215.404 100.716 0,15% Aktien
SECTOR GAMMA AS $8.157.000 100.000 0,15% Aktien
WCM INVESTMENT MANAGEMENT, LLC $7.651.184 93.799 0,14% Aktien
PANAGORA ASSET MANAGEMENT INC $7.256.141 88.956 0,13% Aktien
VOYA INVESTMENT MANAGEMENT LLC $7.239.501 88.752 0,13% Aktien
ALLIANCEBERNSTEIN L.P. $7.217.488 105.937 0,13% Aktien
Aquatic Capital Management LLC $6.808.648 83.470 0,13% Aktien
XTX Topco Ltd $6.682.459 81.923 0,12% Aktien
MOORE CAPITAL MANAGEMENT, LP $6.165.713 75.588 0,11% Aktien
PINNACLE ASSOCIATES LTD $5.745.383 70.435 0,11% Aktien
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $5.744.722 84.320 0,11% Aktien
VANGUARD ASSET MANAGEMENT, Ltd $5.614.300 68.828 0,10% Aktien
Capricorn Fund Managers Ltd $5.212.323 63.900 0,10% Aktien
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5.000.241 61.300 0,09% Kaufoption
INTECH INVESTMENT MANAGEMENT LLC $4.696.882 57.581 0,09% Aktien
ExodusPoint Capital Management, LP $4.672.166 57.278 0,09% Aktien
LOS ANGELES CAPITAL MANAGEMENT LLC $4.561.884 55.926 0,08% Aktien
BARCLAYS PLC $4.169.858 51.120 0,08% Aktien
ORBIMED ADVISORS LLC $4.005.087 49.100 0,07% Aktien
MetLife Investment Management, LLC $3.932.653 48.212 0,07% Aktien
Point72 Europe (London) LLP $3.829.919 62.407 0,07% Aktien
MILLENNIUM MANAGEMENT LLC $3.792.516 46.494 0,07% Aktien
Phocas Financial Corp. $3.766.087 46.170 0,07% Aktien
MARTINGALE ASSET MANAGEMENT L P $3.627.826 44.475 0,07% Aktien
Quadrature Capital Ltd $3.589.488 44.005 0,07% Aktien
SUSQUEHANNA INTERNATIONAL GROUP, LLP $3.531.981 43.300 0,07% Verkaufsoption
STATE OF WISCONSIN INVESTMENT BOARD $3.436.299 42.127 0,06% Aktien
CREDIT AGRICOLE S A $3.344.370 41.000 0,06% Aktien
Fisher Asset Management, LLC $3.322.345 40.730 0,06% Aktien
HSBC HOLDINGS PLC $3.200.425 38.732 0,06% Aktien
NEW YORK STATE COMMON RETIREMENT FUND $3.134.490 38.427 0,06% Aktien
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $3.114.179 38.178 0,06% Aktien
CenterBook Partners LP $3.082.938 37.795 0,06% Aktien
Rafferty Asset Management, LLC $3.069.805 37.634 0,06% Aktien
FIFTH THIRD BANCORP $3.044.843 37.328 0,06% Aktien
BURNEY CO/ $3.044.192 37.320 0,06% Aktien
Vanguard Global Advisers, LLC $3.033.180 37.185 0,06% Aktien
Arrowpoint Investment Partners (Singapore) Pte. Ltd. $3.007.731 36.873 0,06% Aktien
Louisiana State Employees Retirement System $2.969.148 36.400 0,05% Aktien
JANE STREET GROUP, LLC $2.854.950 35.000 0,05% Verkaufsoption
CASTLEARK MANAGEMENT LLC $2.765.223 33.900 0,05% Aktien

Unternehmensinsider 33 Insider · 13 Führungskräfte · 14 Direktoren

Insider Rolle Letzte Aktivität Gehaltene Aktien Käufe 12m Verkäufe 12m Netto 12m
Stuart Walter Peltz Chief Executive Officer 1. Februar 2022 S 38.728 0 0 $0
Pierre Gravier CHIEF FINANCIAL OFFICER 14. Juli 2026 S 83.986 0 1 $-280.743
Emily Luisa Hill Chief Financial Officer 1. Februar 2022 S 37.169 0 0 $0
Shane William Charles Kovacs Chief Financial Officer 9. Mai 2017 M 37.850 0 0 $0
Claudia De Oliveira Ribeiro Hirawat President 15. Januar 2015 M 39.247 0 0 $0
Marcio Souza Chief Operating Officer 10. Februar 2020 M 6.744 0 0 $0
Neil Gregory Almstead CHIEF TECHNICAL OPS OFFICER 9. Juli 2026 M 60.299 0 20 $-9.184.852
Mark Elliott Boulding EXEC. VP AND CLO 6. Juli 2026 M 105.272 0 12 $-1.254.986
Christine Marie Utter SVP, CHIEF ACCOUNTING OFFICER 17. Juni 2026 M 70.199 0 1 $-1.487.474
Eric Pauwels CHIEF BUSINESS OFFICER 10. Juni 2026 S 73.411 0 28 $-7.477.160
Mark Rothera Chief Commercial Officer 24. Mai 2017 M 33.739 0 0 $0
Tuyen Ong Chief Medical Officer 3. Januar 2017 A 6.000 0 0 $0
Robert J. Spiegel Chief Medical Officer 4. Januar 2016 A 3.239 0 0 $0
Hege Elisabeth Sollie-Zetlmayer Direktor 28. Juli 2026 A 52.526 0 0 $0
Mary L. Smith Direktor 9. Juli 2026 M 21.813 0 2 $-1.425.060
Stephanie Okey Direktor 7. Januar 2022 A 4.163 0 0 $0
Emma Reeve Direktor 7. Januar 2022 A 7.528 0 0 $0
Allan Steven Jacobson Direktor 7. Januar 2022 A 8.348 0 0 $0
Dawn Svoronos Direktor 7. Januar 2022 A 29.755 0 0 $0
Jerome B Zeldis Direktor 7. Januar 2022 A 6.500 0 0 $0
Cameron Geoffrey Mcdonough Direktor 3. Januar 2017 A 0 0 $0
Adam Koppel Direktor 3. Januar 2017 A 2.333.333 0 0 $0
Ronald C Renaud JR Direktor 3. Januar 2017 A 0 0 $0
Richard Aldrich Direktor 8. Juni 2015 M 0 0 0 $0
Michael L Kranda Direktor 16. März 2015 S 2.242 0 0 $0
Axel Bolte Direktor 25. Juni 2013 P 20.000 0 0 $0
HBM Healthcare Investments (Cayman) Ltd. 10%-Eigentümer 17. Dezember 2013 S 2.441.504 0 0 $0
Matthew B. Klein 4. August 2026 S 383.868 0 1 $-705.722
Michael Schmertzler 2. Januar 2026 A 163.266 0 0 $0
Glenn Steele JR MD PHD 2. Januar 2026 A 22.500 0 1 $-916.200
David P Southwell 2. Januar 2026 A 20.850 0 0 $0
Complete Pharma Holdings II, LLC 28. April 2017 J 0 0 0 $0
CREDIT SUISSE/ 25. Juni 2013 C 2.256.882 0 0 $0

Insider aus SEC-Einreichungen Form 3/4/5; Netto = nur P/S aus offenen Märkten

Aktivisten & 5%+-Eigentümer 3 Beteiligungen

Investoren mit SEC Schedule 13D — wirtschaftliches Eigentum über 5% mit der Absicht, Einfluss auf den Emittenten zu nehmen (aktivistische Beteiligungen, Board-Kampagnen, M&A). Jede Zeile zeigt den zuletzt bekannten Stand der Position dieses Melders.

Anmelder Eingereicht Beteiligung Status Zweck Einreichung
Brookside Capital Partners Fund, L.P., Brookside Capital Trading Fund, L.P. ×5 Einreichungen 30. Januar 2015 Erste Einreichung SEC
HBM Healthcare Investments (Cayman) Ltd. (“HBM”) ×2 Einreichungen 12. November 2014 Erste Einreichung SEC
HBM Healthcare Investments (Cayman) Ltd. 5. Juli 2013 Erste Einreichung SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF-Besitz Gehalten von 87 ETFs

Gewichtung spiegelt nur direkte Aktienbestände (N-PORT) wider; gehebelte oder derivatbasierte Fonds können zusätzliche Swap-Exposure halten, die hier nicht angezeigt wird.

Fonds Gewicht Anteile Stand Quelle
IBRN · iShares Trust 3,81% 4.145 SH 8. August 2026 Täglich
PSCH · Invesco Exchange-Traded Fund Trust … 3,08% 71.992 SH 8. August 2026 Täglich
PBE · Invesco Exchange-Traded Fund Trust 2,59% 128.216 SH 8. August 2026 Täglich
XSMO · Invesco Exchange-Traded Fund Trust 1,52% 642.023 SH 8. August 2026 Täglich
BBP · ETFis Series Trust I 1,37% 12.510 NS 30. April 2026 N-PORT
SIXS · EXCHANGE TRADED CONCEPTS TRUST 1,30% 22.380 NS 31. Mai 2026 N-PORT
RZG · Invesco Exchange-Traded Fund Trust 1,25% 23.662 SH 8. August 2026 Täglich
GURU · Global X Funds 1,03% 9.268 NS 30. April 2026 N-PORT
LABU · Direxion Shares ETF Trust 0,93% 73.928 NS 30. April 2026 N-PORT
VAMO · Cambria ETF Trust 0,83% 10.625 NS 30. April 2026 N-PORT
VIOG · VANGUARD ADMIRAL FUNDS 0,74% 98.733 SH 8. August 2026 Täglich
VMAX · Lattice Strategies Trust 0,72% 5.120 NS 30. April 2026 N-PORT
IJT · iShares Trust 0,66% 770.376 SH 8. August 2026 Täglich
FNY · First Trust Exchange-Traded AlphaDE… 0,51% 40.257 NS 30. April 2026 N-PORT
MMSC · First Trust Exchange-Traded Fund VI… 0,49% 3.490 NS 31. Mai 2026 N-PORT
CLSE · Trust for Professional Managers 0,49% 40.488 NS 31. Mai 2026 N-PORT
IBB · iShares Trust 0,44% 588.017 SH 8. August 2026 Täglich
HQGO · Lattice Strategies Trust 0,43% 3.203 NS 30. April 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0,41% 4.514 SH 8. August 2026 Täglich
OASC · Unified Series Trust 0,40% 4.569 NS 31. Mai 2026 N-PORT
BRNY · EA Series Trust 0,40% 34.057 NS 30. April 2026 N-PORT
VIOO · VANGUARD ADMIRAL FUNDS 0,37% 290.018 SH 8. August 2026 Täglich
XJR · iShares Trust 0,37% 9.802 SH 8. August 2026 Täglich
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,34% 35.034 NS 31. Mai 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0,34% 75.795 SH 8. August 2026 Täglich
ESSC · Strategy Shares 0,34% 1.335 NS 30. April 2026 N-PORT
IJR · iShares Trust 0,32% 5.058.562 SH 8. August 2026 Täglich
IWO · iShares Trust 0,31% 641.280 SH 8. August 2026 Täglich
BIB · ProShares Trust 0,31% 3.062 NS 31. Mai 2026 N-PORT
FSCC · Federated Hermes ETF Trust 0,31% 11.451 NS 31. Mai 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0,30% 39.411 NS 31. Mai 2026 N-PORT
SAA · ProShares Trust 0,26% 961 NS 31. Mai 2026 N-PORT
ROUS · Lattice Strategies Trust 0,25% 22.443 NS 30. April 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0,24% 27.276 NS 30. April 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0,23% 2.877 NS 30. April 2026 N-PORT
AFSM · First Trust Exchange-Traded Fund VI… 0,23% 3.003 NS 31. Mai 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0,20% 477.030 SH 8. August 2026 Täglich
FNX · First Trust Exchange-Traded AlphaDE… 0,20% 39.967 NS 30. April 2026 N-PORT
VBK · VANGUARD INDEX FUNDS 0,19% 1.099.640 SH 8. August 2026 Täglich
PRFZ · Invesco Exchange-Traded Fund Trust 0,18% 72.691 SH 8. August 2026 Täglich
IWM · iShares Trust 0,18% 2.102.256 SH 8. August 2026 Täglich
LRGF · iShares Trust 0,16% 84.151 SH 8. August 2026 Täglich
ISCG · iShares Trust 0,16% 22.792 SH 8. August 2026 Täglich
RSSL · Global X Funds 0,16% 34.125 NS 30. April 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0,15% 11.071 NS 30. April 2026 N-PORT
ITWO · ProShares Trust 0,15% 3.710 NS 31. Mai 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0,14% 35.428 SH 8. August 2026 Täglich
FSMD · FIDELITY COVINGTON TRUST 0,14% 49.932 NS 30. April 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0,14% 5.350 SH 8. August 2026 Täglich
SMDX · Tidal Trust III 0,13% 2.579 NS 30. April 2026 N-PORT