CELC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $72.10
Market Cap (MRQ) $3.53B
P/E -19.0
EPS $-3.79
ROE -244.3%
52W Range $45–$151

CELC Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
range
bars

Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.

10-Year Performance Revenue, net income, margins and EPS trends

06
EPS$-3.79
2022-12-31 → 2025-12-31
Free Cash Flow$-154M
2017-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend CELC 5Y avg Peer Median Verdict
P/E -19.05Y avg ≈-10.4 ≈-10.4 · ·
P/B (MRQ) -276.05Y avg ≈14.4 ≈14.4 · ·
Price / FCF (TTM) -18.45Y avg ≈-13.4 ≈-13.4 · ·
Price / Cash Flow (TTM) -18.45Y avg ≈-13.5 ≈-13.5 · ·
Price / Tangible Book (MRQ) -56.25Y avg ≈12.0 ≈12.0 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -0.76%
Next Report Nov 10, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 13, 2026 $-1.23 $-1.19 -3.6%
March 31, 2026 May 14, 2026 $-0.97 $-1.07 9.7%
Dec. 31, 2025 $-0.97 $-1.06 8.7%
Sept. 30, 2025 $-0.92 $-1.03 10.6%
June 30, 2025 $-1.04 $-0.90 -15.3%
March 31, 2025 $-0.86 $-0.88 2.2%
Dec. 31, 2024 $-0.85 $-0.72 -17.6%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 15
Metric Trend 2025202420232022202120202019201820172016
R&D Expense $145M$104M$61M$35M$26M$8M$6M$6M$5M$3M
SG&A Expense $27M$9M$6M$4M$3M$2M$2M$2M$972.5K$263.7K
Operating Expenses $172M$113M$66M$39M$28M$10M$8M$8M$6M$3M
Operating Income $-172M$-113M$-66M$-39M$-28M$-10M$-8M$-8M$-6M$-3M
Interest Expense ··$5M$2M$1M$120$159$111$451.7K$0
Interest Income $12M$12M$8M$1M$13.3K$82.1K$446.1K$448.8K$152.9K$18.0K
Other Non-op $-5M$1M$2M$-978.9K$-1M$82.0K$445.9K$451.7K$-298.8K$18.0K
Pretax Income $-177M$-112M$-64M$-40M$-30M$-9M$-7M$-7M$-6M$-3M
Income Tax ······$0$0$0$0
Net Income $-177M$-112M$-64M$-40M$-30M$-9M$-7M$-7M$-6M$-3M
EPS (Basic) $-3.79$-2.83$-2.69$-2.64$-2.21·····
EPS (Diluted) $-3.79$-2.83$-2.69$-2.64······
Shares (Basic) 46,757,69139,449,39323,679,47215,418,54313,382,553·····
Shares (Diluted) 46,757,69139,449,39323,679,47215,418,543······
EBITDA $-172M$-113M$-66M·$-28M$-10M$-8M$-8M$-6M·
Balance Sheet 22
Metric Trend 2025202420232022202120202019201820172016
Cash & Equivalents $166M$23M$31M$25M$84M$12M$19M$16M$3M$6M
Short-term Investments $276M$213M$150M$144M··$0$9M$22M$0
Prepaid Expense ···$7M$722.7K$317.0K$274.6K$269.9K$209.7K$0
Other Current Assets $5M$3M$10M$7M······
Current Assets $466M$245M$191M$175M$85M$12M$19M$25M$24M$6M
PP&E (Net) $499.0K$336.0K$228.8K$260.3K$312.4K$558.9K$833.5K$813.6K$280.1K$144.9K
PP&E (Gross) $3M$2M$2M$2M$2M$2M$2M$1M$540.2K$300.3K
Accum. Depreciation $2M$2M$2M$2M$2M$1M$819.9K$480.9K$260.1K$155.4K
Other Non-current Assets $349.0K·········
Total Assets $467M$245M$191M$176M$86M$13M$20M$26M$32M$6M
Accounts Payable $6M$9M$5M$3M$2M$217.4K$142.8K$119.8K$71.9K$331.5K
Accrued Liabilities ·$22M$9M$4M$802.9K$774.6K$584.3K$536.8K$506.1K$113.8K
Current Liabilities $44M$32M$14M$7M$3M$1M$911.3K$662.3K$578.1K$445.4K
Capital Leases ·$54.0K$225.9K$61.0K$61.8K$60.9K$57.8K$0$0·
Total Liabilities $366M$130M$51M$42M$17M$1M$983.2K$682.2K$578.1K$445.4K
Long-term Debt $138M$105M$38M$36M$16M·····
Common Stock $48.0K$37.0K$25.5K$21.7K$14.9K$10.3K$10.3K$10.2K$10.1K$0
Paid-in Capital $549M$387M$300M$230M$125M$38M$36M$35M$33M$593.4K
Retained Earnings $-449M$-272M$-160M$-96M$-56M$-26M$-17M$-9M$-2M$-8M
Stockholders' Equity $101M$116M$140M$134M$69M$12M$19M$25M$31M$6M
Liabilities + Equity $467M$245M$191M$176M$86M$13M$20M$26M$32M$6M
Shares Outstanding 48,244,96037,143,24225,506,01221,667,25014,918,88710,299,82210,253,98810,186,38210,087,5160
Cash Flow 8
Metric Trend 2025202420232022202120202019201820172016
Stock-based Comp $21M$7M$5M$5M$3M$2M$1M$1M$874.4K$187.3K
Operating Cash Flow $-153M$-83M$-54M$-36M$-20M$-7M$-6M$-6M$-5M$-3M
CapEx $249.0K$250.0K$97.6K$158.8K$81.9K$89.4K$-380.2K$629.6K$239.8K$40.9K
Investing Cash Flow $-64M$-63M$-5M$-144M$-81.4K$-89.4K$9M$19M$-29M$-40.9K
Financing Cash Flow $361M$138M$65M$120M$93M$138.0K$259.3K$236.7K$31M$4M
Net Change in Cash ·····$-7M$3M$13M$-3M$789.1K
Free Cash Flow $-154M$-84M$-54M·$-20M$-7M$-6M$-7M$-5M·
Levered FCF ·····$-7M$-6M$-7M$-6M·
Profitability 3
Metric Trend 2025202420232022202120202019201820172016
ROA -49.8%-51.2%-34.8%·-59.9%-57.0%-31.8%-25.8%-32.9%·
ROE -244.3%-84.3%-54.8%·-41.3%-74.4%-36.8%-28.6%-33.8%·
ROIC ·····-81.7%-40.5%-31.3%-19.0%·
Liquidity & Solvency 3
Metric Trend 2025202420232022202120202019201820172016
Current Ratio 10.57.713.4·34.110.321.138.142.4·
Quick Ratio 10.07.412.7·33.69.820.637.641.9·
Interest Coverage ··-12.4·-22.5-79634.7-49089.9-71464.3-13.2·
Per Share 4
Metric Trend 2025202420232022202120202019201820172016
Book Value / Share $2.08$3.11$5.48·$4.61$1.14$1.88$2.49$3.11·
Cash Flow / Share $-3.28$-2.12$-2.27·······
Cash / Share $3.43$0.61$1.20·$5.65$1.13$1.83$1.57$0.26·
EPS (TTM) $-3.79$-2.83$-2.69$-2.64······
Valuation (TTM) 8
Metric Trend 2025202420232022202120202019201820172016
Net Income TTM $-177M$-112M$-64M$-40M$-30M$-9M$-7M$-7M$-6M·
Market Cap $4.81B$486M$372M·$197M$94M$109M$244M$191M·
P/E -26.3-4.6-5.4-5.3······
P/B 47.94.22.7·2.98.15.79.66.1·
P / Tangible Book 47.94.22.72.32.98.1····
P / Cash Flow -31.4-5.8-6.9·-9.7-13.2-18.2-40.2-38.6·
P / FCF -31.3-5.8-6.9·-9.6-13.4-17.1-36.4-36.8·
Earnings Yield -3.8%-21.6%-18.5%-18.8%······

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-177M $-112M $-64M $-40M $-30M
Diluted EPS $-3.79 $-2.83 $-2.69 $-2.64 ·

Institutional owners (13F) 291 filers · $6.2B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 291
Value held $6.2B
New positions 60
Exited positions 54
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
60 (-23 vs prior Q) 54 (+26 vs prior Q) 114 (+16 vs prior Q) 77 (-1 vs prior Q) +7.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BAKER BROS. ADVISORS LP $828,150,159 7,915,792 13.38% Shares
Avoro Capital Advisors LLC $355,708,000 3,400,000 5.75% Shares
RTW INVESTMENTS, LP $345,758,952 3,304,903 5.59% Shares
PERCEPTIVE ADVISORS LLC $334,491,064 3,197,200 5.41% Shares
BlackRock, Inc. $315,825,285 3,018,785 5.10% Shares
VANGUARD GROUP INC $227,350,648 2,279,433 3.67% Shares
STATE STREET CORP $204,556,764 1,955,304 3.31% Shares
VANGUARD CAPITAL MANAGEMENT LLC $196,072,213 1,874,137 3.17% Shares
NEA Management Company, LLC $178,958,892 1,710,561 2.89% Shares
Soleus Capital Management, L.P. $178,305,749 1,704,318 2.88% Shares
BANK OF AMERICA CORP /DE/ $153,928,139 1,471,307 2.49% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $151,805,085 1,451,014 2.45% Shares
MORGAN STANLEY $139,620,204 1,334,545 2.26% Shares
TANG CAPITAL MANAGEMENT LLC $137,532,824 1,314,594 2.22% Shares
TORONTO DOMINION BANK $131,691,262 1,258,758 2.13% Shares
GEODE CAPITAL MANAGEMENT, LLC $116,327,807 1,111,662 1.88% Shares
WELLINGTON MANAGEMENT GROUP LLP $94,847,969 906,595 1.53% Shares
GOLDMAN SACHS GROUP INC $91,066,374 870,449 1.47% Shares
Point72 Asset Management, L.P. $68,098,832 650,916 1.10% Shares
Hood River Capital Management LLC $65,744,359 628,411 1.06% Shares
ALLIANCEBERNSTEIN L.P. $60,599,437 530,922 0.98% Shares
FMR LLC $57,434,619 548,983 0.93% Shares
Apis Capital Advisors, LLC $56,285,560 538,000 0.91% Shares
Holocene Advisors, LP $55,777,839 533,147 0.90% Shares
UBS Group AG $54,501,371 520,946 0.88% Shares
FULLER & THALER ASSET MANAGEMENT, INC. $53,816,124 514,396 0.87% Shares
SILVERARC CAPITAL MANAGEMENT, LLC $52,414,202 500,996 0.85% Shares
BNP PARIBAS FINANCIAL MARKETS $51,718,897 494,350 0.84% Shares
Artisan Partners Limited Partnership $48,291,650 461,591 0.78% Shares
AMERICAN CENTURY COMPANIES INC $46,546,597 444,909 0.75% Shares
WESTFIELD CAPITAL MANAGEMENT CO LP $43,711,910 417,816 0.71% Shares
Boxer Capital Management, LLC $43,577,368 416,530 0.70% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $42,120,012 402,600 0.68% Call option
VANGUARD PORTFOLIO MANAGEMENT LLC $39,756,960 380,013 0.64% Shares
Saturn V Capital Management LP $38,742,669 370,318 0.63% Shares
JENNISON ASSOCIATES LLC $37,555,650 358,972 0.61% Shares
NORTHERN TRUST CORP $37,340,866 356,919 0.60% Shares
First Turn Management, LLC $34,430,547 329,101 0.56% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $33,571,826 320,893 0.54% Shares
Driehaus Capital Management LLC $31,789,833 303,860 0.51% Shares
FRANKLIN RESOURCES INC $31,181,676 298,047 0.50% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $31,166,298 297,900 0.50% Put option
Pfizer Inc $29,550,417 295,652 0.48% Shares
VOYA INVESTMENT MANAGEMENT LLC $29,170,880 278,827 0.47% Shares
VANGUARD FIDUCIARY TRUST CO $29,058,100 277,749 0.47% Shares
CAPITOLIS LIQUID GLOBAL MARKETS LLC $28,990,202 277,100 0.47% Shares
Caption Management, LLC $28,467,102 272,100 0.46% Put option
Focus Partners Wealth $24,330,323 232,559 0.39% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $21,396,000 204,516 0.35% Shares
JANE STREET GROUP, LLC $20,871,690 199,500 0.34% Call option

Show all 291 institutional owners →

Activists & 5%+ owners 2 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 10 insiders · 3 officers · 9 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
SULLIVAN BRIAN F Chief Executive Officer Aug. 14, 2026 A 1,450,199 0 0 $0
Vicky Hahne Chief Financial Officer Aug. 14, 2026 A 37,808 0 0 $0
Lance G. Laing Chief Science Officer Aug. 14, 2026 A 1,271,000 0 0 $0
Polly A. Murphy Director June 10, 2026 G 6,530 0 0 $0
Richard E Buller Director June 10, 2026 G 1,530 0 12 $-2,397,281
Charles R Romp Director June 5, 2026 A 1,745 0 0 $0
Leo Furcht Director June 5, 2026 A 12,530 0 0 $0
David Dalvey Director June 5, 2026 A 1,530 0 3 $-7,417,600
Richard Nigon Director June 5, 2026 A 80,565 0 0 $0
Maureen Therese Cronin Director May 16, 2019 A 7,821 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 24 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
LABU · Direxion Shares ETF Trust 0.67% 38,241 NS July 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.65% 3,510 NS July 31, 2026 N-PORT
ESSC · Strategy Shares 0.36% 1,501 NS July 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.24% 41,164 SH Aug. 19, 2026 Daily
IWO · iShares Trust 0.22% 360,886 SH Sept. 11, 2026 Daily
PWS · Pacer Funds Trust 0.19% 522 NS July 31, 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0.15% 28,672 SH Aug. 19, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.12% 221,459 SH Aug. 19, 2026 Daily
IWM · iShares Trust 0.11% 982,888 SH Sept. 11, 2026 Daily
RSSL · Global X Funds 0.11% 18,423 NS July 31, 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0.10% 972 NS July 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.07% 6,009 NS July 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.04% 436,100 SH Aug. 19, 2026 Daily
WSML · iShares Trust 0.02% 1,717 SH Sept. 11, 2026 Daily
VHT · VANGUARD WORLD FUND 0.02% 47,279 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.02% 7,465 NS July 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.01% 1,394,332 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.01% 3,159 SH Aug. 19, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.01% 3,372 SH Oct. 1, 2026 Daily
ITOT · iShares Trust 0.00% 51,216 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 9,672 SH Sept. 11, 2026 Daily
ISCB · iShares Trust · 1,011 SH Sept. 11, 2026 Daily
ISCV · iShares Trust · 4,864 SH Sept. 11, 2026 Daily
SMLF · iShares Trust · 39,232 SH Sept. 11, 2026 Daily

CELC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 18 analysts BUY
Median target $160.00 +121.9%
7 38.9% Strong Buy
10 55.6% Buy
1 5.6% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

11 analysts · 2026-10-01

Mean target $159.64 +121.4%

← Below all targets Current price $72.10
Low$134.00 Mean$159.64 High$177.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CELC $4.81B -26.3 · · -244.3% ·
LEGN · -26.8 · · -29.1% ·
PBLS · · · · · ·
IDYA $3.04B -27.0 3024.4% -52.0% -11.5% ·
VCYT $3.34B 51.3 16.0% 12.8% 5.2% 70.1%
CDNA $959M -47.1 13.8% -5.6% -6.8% ·
ACAD $4.55B 11.6 11.9% 36.5% 38.1% ·
DNLI $2.58B -5.6 204.7% · -50.2% ·
RCUS $2.99B -7.2 -4.3% -142.9% -59.8% ·
ARQT $3.58B -223.4 91.3% -4.3% -9.8% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

Pick the metrics that matter to you — click the + next to any row in Full Fundamentals above.

Your selection is saved and follows you across all tickers.

Source: SEC 10-Q filed Aug 13, 2026