IDYA IDEAYA Biosciences, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$38.86
Price · Aug 19, 2026
Fundamentals as of Aug 4, 2026

About IDEAYA Biosciences, Inc. - Common Stock Company overview from Wikipedia

IDYA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$38.86
Market Cap
$3.41B
P/E (TTM)
-30.4
EPS (TTM)
$-1.28
Revenue (TTM)
$219M
Div Yield
ROE
-11.5%
Debt/Equity
52W Range
$23 – $41

IDYA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $219M
7-point trend, +218710000.00
2019-12-31 2025-12-31
EPS $-1.28
6-point trend, +8.6%
2020-12-31 2025-12-31
Free Cash Flow $-73M
7-point trend, -80.7%
2019-12-31 2025-12-31
Margins -52.0%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
IDYA
Peer Median
P/E (TTM)
5-point trend, -61.1%
-30.4
P/S (TTM)
5-point trend, -57.4%
15.6
18.3
P/B
5-point trend, -1.8%
3.3
3.3
Price / FCF
5-point trend, -165.0%
-46.4

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
IDYA
Peer Median
Operating Margin
5-point trend, +59.5%
-72.8%
Net Profit Margin
5-point trend, +70.8%
-52.0%
-180.4%
ROA
5-point trend, +30.5%
-10.2%
-36.2%
ROE
5-point trend, +28.6%
-11.5%
-43.7%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
IDYA
Peer Median
Current Ratio
5-point trend, +104.0%
11.3
9.7
Quick Ratio
5-point trend, +98.1%
10.9

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
IDYA
Peer Median
Revenue YoY
5-point trend, +682.8%
3024.4%
Revenue CAGR 3Y
5-point trend, +682.8%
62.5%
Revenue CAGR 5Y
5-point trend, +682.8%
62.1%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
IDYA
Peer Median
EPS (Diluted)
5-point trend, +9.2%
$-1.28

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
IDYA
Peer Median

IDYA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 22 analysts
  • Strong Buy 7 31.8%
  • Buy 13 59.1%
  • Hold 2 9.1%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

13 analysts · 2026-08-13
Median target $51.00 +31.2%
Mean target $52.15 +34.2%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.25%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-1.22 $-1.11 -0.11%
March 31, 2026 $-1.11 $-1.01 -0.10%
Dec. 31, 2025 $-0.94 $-0.99 0.05%
Sept. 30, 2025 $1.33 $-0.56 1.9%
June 30, 2025 $-0.88 $-0.81 -0.07%
March 31, 2025 $-0.82 $-0.67 -0.15%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
IDYA $3.04B -27.0 3024.4% -52.0% -11.5%
LEGN
DNLI $2.58B -5.6 204.7% -50.2%
RCUS $2.99B -7.2 -4.3% -142.9% -59.8%
VKTX $4.04B -11.0 -47.3%
VCYT $3.34B 51.3 16.0% 12.8% 5.2% 70.1%
IOVA $1.12B -2.5 60.6% -148.4% -56.0%
ARQT $3.58B -223.4 91.3% -4.3% -9.8%
GRAL $3.45B -7.7 17.2% -277.5% -16.7%
CLDX $1.81B -7.0 -78.0% -16748.0% -43.8%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 14
Annual Income Statement data for IDYA
Metric Trend 2025202420232022202120202019
Revenue 7-point trend, +218710000.00 $219M $7M $23M $51M $28M $20M $0
R&D Expense 7-point trend, +817.0% $315M $295M $130M $90M $58M $40M $34M
SG&A Expense 7-point trend, +536.2% $63M $39M $28M $24M $20M $15M $10M
Operating Expenses 7-point trend, +753.9% $378M $334M $158M $113M $78M $55M $44M
Operating Income 7-point trend, -259.9% $-159M $-327M $-134M $-63M $-50M $-35M $-44M
Interest Income · · · · · · $2M
Other Non-op 7-point trend, +1886.7% $46M $52M $21M $4M $506.0K $849.0K $2M
Income Tax Flat — no change across 7 periods $0 $0 $0 $0 $0 $0 $0
Net Income 7-point trend, -170.9% $-114M $-274M $-113M $-59M $-50M $-34M $-42M
EPS (Basic) 6-point trend, +8.6% $-1.28 $-3.36 $-1.96 $-1.42 $-1.41 $-1.40 ·
EPS (Diluted) 6-point trend, +8.6% $-1.28 $-3.36 $-1.96 $-1.42 $-1.41 $-1.40 ·
Shares (Basic) 6-point trend, +257.9% 88,485,238 81,678,069 57,519,929 41,444,696 35,252,443 24,721,775 ·
Shares (Diluted) 6-point trend, +257.9% 88,485,238 81,678,069 57,519,929 41,444,696 35,252,443 24,721,775 ·
EBITDA 7-point trend, -264.0% $-157M $-325M $-132M $-60M $-49M $-34M $-43M
Balance Sheet 22
Annual Balance Sheet data for IDYA
Metric Trend 2025202420232022202120202019
Cash & Equivalents 7-point trend, +231.2% $113M $84M $157M $69M $92M $72M $34M
Short-term Investments 7-point trend, +711.5% $527M $592M $368M $296M $155M $212M $65M
Receivables 5-point trend, -99.8% · $3.0K $18.0K $211.0K $1M $2M ·
Prepaid Expense 7-point trend, +691.9% $21M $13M $8M $5M $3M $3M $3M
Current Assets 7-point trend, +555.9% $667M $690M $533M $370M $251M $289M $102M
PP&E (Net) 7-point trend, +77.0% $8M $9M $6M $7M $5M $4M $5M
PP&E (Gross) 7-point trend, +214.0% $22M $21M $16M $14M $10M $8M $7M
Accum. Depreciation 7-point trend, +466.6% $14M $12M $10M $8M $6M $4M $3M
Other Non-current Assets 5-point trend, +56.2% · · $25.0K $99.0K $291.0K $82.0K $16.0K
Total Assets 7-point trend, +881.7% $1.11B $1.12B $649M $388M $381M $298M $113M
Accounts Payable 7-point trend, +2380.1% $18M $15M $7M $4M $2M $953.0K $709.0K
Accrued Liabilities 7-point trend, +714.1% $41M $30M $19M $17M $12M $9M $5M
Current Liabilities 7-point trend, +747.5% $59M $46M $27M $32M $45M $39M $7M
Capital Leases 7-point trend, +390.0% $28M $19M $1M $2M $3M $5M $6M
Other Non-current Liabilities 2-point trend, -64.7% · · · · · $12.0K $34.0K
Total Liabilities 7-point trend, +585.6% $86M $65M $28M $39M $80M $100M $13M
Common Stock 7-point trend, +350.0% $9.0K $9.0K $7.0K $5.0K $4.0K $3.0K $2.0K
Retained Earnings 7-point trend, -696.3% $-737M $-623M $-348M $-235M $-177M $-127M $-92M
AOCI 7-point trend, +3387.7% $2M $812.0K $562.0K $-3M $-712.0K $7.0K $65.0K
Stockholders' Equity 7-point trend, +918.9% $1.02B $1.06B $621M $349M $302M $198M $100M
Liabilities + Equity 7-point trend, +881.7% $1.11B $1.12B $649M $388M $381M $298M $113M
Shares Outstanding 7-point trend, +331.7% 87,796,561 86,503,509 65,039,369 48,193,179 38,533,045 29,537,216 20,339,461
Cash Flow 12
Annual Cash Flow data for IDYA
Metric Trend 2025202420232022202120202019
D&A 7-point trend, +116.9% $3M $2M $2M $2M $2M $1M $1M
Stock-based Comp 7-point trend, +2027.1% $46M $35M $18M $12M $8M $4M $2M
Other Non-cash 7-point trend, -727.6% $-6M $-10M $-23M $-42M $-16M $85M $-751.0K
Operating Cash Flow 7-point trend, -80.9% $-71M $-248M $-115M $-87M $-56M $55M $-39M
CapEx 7-point trend, +75.0% $2M $4M $2M $3M $3M $493.0K $1M
Investing Cash Flow 7-point trend, +2989.4% $70M $-503M $-158M $-33M $-70M $-146M $2M
Stock Issued 7-point trend, -100.0% $0 $274M $281M $86M $86M $101M $50M
Net Stock Activity 6-point trend, -100.0% $0 $274M $281M $86M $86M $101M ·
Financing Cash Flow 7-point trend, -41.2% $30M $678M $363M $97M $145M $129M $51M
Net Change in Cash 7-point trend, +111.3% $29M $-73M $89M $-23M $20M $38M $14M
Taxes Paid 5-point trend, -100.0% · · $0 $0 $4.0K $1.0K $1.0K
Free Cash Flow 7-point trend, -80.7% $-73M $-251M $-118M $-91M $-58M $55M $-41M
Profitability 5
Annual Profitability data for IDYA
Metric Trend 2025202420232022202120202019
Operating Margin 6-point trend, +59.7% -72.8% -4671.1% -574.9% -122.7% -179.9% -180.9% ·
Net Margin 6-point trend, +70.6% -52.0% -3921.1% -483.0% -115.2% -178.1% -176.6% ·
EBITDA Margin 6-point trend, +58.8% -71.6% -4637.0% -564.3% -118.6% -173.7% -173.8% ·
ROA 7-point trend, +74.6% -10.2% -30.9% -21.8% -15.2% -14.6% -16.8% -40.1%
ROE 7-point trend, +71.2% -11.5% -24.5% -20.0% -16.3% -16.1% -17.5% -39.8%
Liquidity & Solvency 2
Annual Liquidity & Solvency data for IDYA
Metric Trend 2025202420232022202120202019
Current Ratio 7-point trend, -22.6% 11.3 15.0 19.7 11.7 5.6 7.5 14.6
Quick Ratio 7-point trend, -23.8% 10.9 14.7 19.4 11.5 5.5 7.4 14.3
Efficiency 2
Annual Efficiency data for IDYA
Metric Trend 2025202420232022202120202019
Asset Turnover 6-point trend, +106.2% 0.2 0.0 0.0 0.1 0.1 0.1 ·
Receivables Turnover 5-point trend, +3102.3% · 666.7 204.2 77.5 18.8 20.8 ·
Per Share 5
Annual Per Share data for IDYA
Metric Trend 2025202420232022202120202019
Book Value / Share 7-point trend, +136.0% $11.65 $12.24 $9.55 $7.25 $7.82 $6.71 $4.94
Revenue / Share 4-point trend, +101.1% $2.47 $0.09 $0.41 $1.23 · · ·
Cash Flow / Share 4-point trend, +61.8% $-0.80 $-3.03 $-2.00 $-2.10 · · ·
Cash / Share 7-point trend, -23.3% $1.29 $0.98 $2.41 $1.42 $2.39 $2.44 $1.67
EPS (TTM) 6-point trend, +8.6% $-1.28 $-3.36 $-1.96 $-1.42 $-1.41 $-1.40 ·
Growth Rates 3
Annual Growth Rates data for IDYA
Metric Trend 2025202420232022202120202019
Revenue YoY 5-point trend, +6931.9% 3024.4% -70.1% -54.1% 82.3% 43.0% · ·
Revenue CAGR 3Y 3-point trend, +913.6% 62.5% -37.0% 6.2% · · · ·
Revenue CAGR 5Y 62.1% · · · · · ·
Valuation (TTM) 10
Annual Valuation (TTM) data for IDYA
Metric Trend 2025202420232022202120202019
Revenue TTM 7-point trend, +218710000.00 $219M $7M $23M $51M $28M $20M $0
Net Income TTM 7-point trend, -170.9% $-114M $-274M $-113M $-59M $-50M $-34M $-42M
Market Cap 7-point trend, +1889.6% $3.04B $2.22B $2.31B $876M $911M $414M $153M
P/E 6-point trend, -170.1% -27.0 -7.6 -18.2 -12.8 -16.8 -10.0 ·
P/S 6-point trend, -34.4% 13.9 317.6 99.0 17.2 32.6 21.2 ·
P/B 7-point trend, +95.3% 3.0 2.1 3.7 2.5 3.0 2.1 1.5
P / Tangible Book 6-point trend, +42.3% 3.0 2.1 3.7 2.5 3.0 2.1 ·
P / Cash Flow 7-point trend, -1000.2% -42.7 -9.0 -20.1 -10.0 -16.3 7.5 -3.9
P / FCF 7-point trend, -1001.3% -41.3 -8.8 -19.7 -9.7 -15.6 7.5 -3.8
Earnings Yield 6-point trend, +63.0% -3.7% -13.1% -5.5% -7.8% -6.0% -10.0% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $219M$7M$23M$51M$28M
Operating Margin % -72.8%-4671.1%-574.9%-122.7%-179.9%
Net Income $-114M$-274M$-113M$-59M$-50M
Diluted EPS $-1.28$-3.36$-1.96$-1.42$-1.41
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 11.315.019.711.75.6
Quick Ratio 10.914.719.411.55.5
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-73M$-251M$-118M$-91M$-58M

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Institutional owners (13F) 307 filers · $2.5B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
71 (+16 vs prior Q) 32 (+3 vs prior Q) 83 (0 vs prior Q) 89 (+12 vs prior Q) +4.1M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
FMR LLC $291,702,935 7,826,749 11.58% Shares
Capital Research Global Investors $199,197,006 5,344,701 7.91% Shares
BAKER BROS. ADVISORS LP $186,723,818 5,010,030 7.41% Shares
STATE STREET CORP $169,537,913 4,548,911 6.73% Shares
VANGUARD CAPITAL MANAGEMENT LLC $154,023,716 4,132,646 6.12% Shares
Logos Global Management LP $111,810,000 3,000,000 4.44% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $101,202,623 2,715,391 4.02% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $101,169,527 2,714,503 4.02% Shares
GEODE CAPITAL MANAGEMENT, LLC $77,954,975 2,091,183 3.10% Shares
DIMENSIONAL FUND ADVISORS LP $58,086,860 1,558,542 2.31% Shares
ALLIANCEBERNSTEIN L.P. $54,229,000 1,627,521 2.15% Shares
FEDERATED HERMES, INC. $53,356,850 1,431,630 2.12% Shares
GSK plc $49,693,321 1,333,333 1.97% Shares
Candriam S.C.A. $40,670,890 1,092,301 1.62% Shares
Sofinnova Investments, Inc. $34,479,185 925,119 1.37% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $33,230,230 891,608 1.32% Shares
Fisher Asset Management, LLC $31,728,173 851,306 1.26% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $30,621,479 821,612 1.22% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $28,134,676 754,888 1.12% Shares
Pictet Asset Management Holding SA $26,561,360 712,674 1.05% Shares
Redmile Group, LLC $23,860,329 640,202 0.95% Shares
VANGUARD FIDUCIARY TRUST CO $23,145,602 621,025 0.92% Shares
Qube Research & Technologies Ltd $22,081,469 592,473 0.88% Shares
Aberdeen Group plc $20,906,010 560,934 0.83% Shares
GOLDMAN SACHS GROUP INC $20,293,627 544,503 0.81% Shares
VANGUARD GROUP INC $19,118,213 553,029 0.76% Shares
NEW YORK STATE COMMON RETIREMENT FUND $18,709,167 501,990 0.74% Shares
DAFNA Capital Management LLC $18,532,135 497,240 0.74% Shares
Sio Capital Management, LLC $17,903,874 480,383 0.71% Shares
TANG CAPITAL MANAGEMENT LLC $16,771,500 450,000 0.67% Shares
Iron Triangle Partners LP $16,160,922 467,484 0.64% Shares
Affinity Asset Advisors, LLC $14,908,000 400,000 0.59% Shares
Walleye Capital LLC $14,393,040 386,183 0.57% Shares
RTW INVESTMENTS, LP $13,803,690 370,370 0.55% Shares
BANK OF AMERICA CORP /DE/ $13,420,442 360,087 0.53% Shares
Rhenman & Partners Asset Management AB $12,813,426 343,800 0.51% Shares
BIT Capital GmbH $11,603,381 311,333 0.46% Shares
GENERAL AMERICAN INVESTORS CO INC $11,488,105 308,240 0.46% Shares
FIRST TRUST ADVISORS LP $11,431,789 306,729 0.45% Shares
CITADEL ADVISORS LLC $11,197,324 300,438 0.44% Shares
Balyasny Asset Management L.P. $11,090,248 297,565 0.44% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $10,267,885 275,500 0.41% Call option
BNP PARIBAS ASSET MANAGEMENT Holding S.A. $10,229,460 274,469 0.41% Shares
Ensign Peak Advisors, Inc $9,957,873 267,182 0.40% Shares
JENNISON ASSOCIATES LLC $9,263,794 248,559 0.37% Shares
Man Group plc $9,144,269 245,352 0.36% Shares
AXA Investment Managers S.A. $8,857,209 325,513 0.35% Shares
ENVESTNET ASSET MANAGEMENT INC $8,352,542 224,109 0.33% Shares
AMERICAN CENTURY COMPANIES INC $7,804,114 209,394 0.31% Shares
SummitTX Capital, L.P. $7,635,579 204,872 0.30% Shares
Susquehanna Portfolio Strategies, LLC $7,627,641 204,659 0.30% Shares
Woodline Partners LP $7,516,129 201,667 0.30% Shares
Burkehill Global Management, LP $7,454,000 200,000 0.30% Shares
SPHERA FUNDS MANAGEMENT LTD. $7,320,126 196,408 0.29% Shares
Verition Fund Management LLC $6,859,693 184,054 0.27% Shares
SCHRODER INVESTMENT MANAGEMENT GROUP $6,825,384 186,741 0.27% Shares
BlackRock, Inc. $6,732,900 180,652 0.27% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $6,365,716 170,800 0.25% Put option
WCM INVESTMENT MANAGEMENT, LLC $6,351,842 173,785 0.25% Shares
Swiss National Bank $5,911,022 158,600 0.23% Shares
VICTORY CAPITAL MANAGEMENT INC $5,641,932 151,380 0.22% Shares
PLATINUM INVESTMENT MANAGEMENT LTD $5,169,647 138,708 0.21% Shares
FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. $5,155,785 138,336 0.20% Shares
TD Asset Management Inc $4,422,831 118,670 0.18% Shares
CONGRESS ASSET MANAGEMENT CO $4,387,164 117,713 0.17% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $4,204,057 112,800 0.17% Shares
RHUMBLINE ADVISERS $4,165,430 111,764 0.17% Shares
MANUFACTURERS LIFE INSURANCE COMPANY, THE $4,009,693 107,585 0.16% Shares
CITIGROUP INC $3,941,750 105,762 0.16% Shares
Odyssean, LLC $3,823,231 102,582 0.15% Shares
Integral Health Asset Management, LLC $3,727,000 100,000 0.15% Shares
Bank of New York Mellon Corp $3,683,692 98,838 0.15% Shares
Atle Fund Management AB $3,521,195 94,478 0.14% Shares
Connor, Clark & Lunn Investment Management Ltd. $3,352,958 89,964 0.13% Shares
ALPS ADVISORS INC $3,308,421 88,769 0.13% Shares
GREAT LAKES ADVISORS, LLC $3,262,802 87,545 0.13% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $3,220,545 96,655 0.13% Shares
UBS Group AG $3,052,860 81,912 0.12% Shares
JANE STREET GROUP, LLC $3,018,870 81,000 0.12% Put option
CITIGROUP INC $2,985,327 80,100 0.12% Call option
KVP Capital Advisors, LP $2,970,419 79,700 0.12% Shares
MARTINGALE ASSET MANAGEMENT L P $2,622,318 70,360 0.10% Shares
Ally Bridge Group (NY) LLC $2,515,725 67,500 0.10% Shares
AQR CAPITAL MANAGEMENT LLC $2,512,184 67,405 0.10% Shares
TEMA ETFS LLC $2,424,325 70,128 0.10% Shares
ASSETMARK, INC $2,423,333 65,021 0.10% Shares
EVENTIDE ASSET MANAGEMENT, LLC $2,422,550 65,000 0.10% Shares
Rafferty Asset Management, LLC $2,390,871 64,150 0.09% Shares
VANGUARD ASSET MANAGEMENT, Ltd $2,374,658 63,715 0.09% Shares
Mitsubishi UFJ Asset Management Co., Ltd. $2,228,001 59,780 0.09% Shares
MML INVESTORS SERVICES, LLC $2,163,412 58,047 0.09% Shares
AlphaCore Capital LLC $2,127,260 57,077 0.08% Shares
Atom Investors LP $2,046,608 54,913 0.08% Shares
XTX Topco Ltd $1,909,678 51,239 0.08% Shares
Lido Advisors, LLC $1,908,671 51,212 0.08% Shares
SEVEN GRAND MANAGERS, LLC $1,863,500 50,000 0.07% Shares
Ghisallo Capital Management LLC $1,863,500 50,000 0.07% Shares
Orion Porfolio Solutions, LLC $1,839,339 49,352 0.07% Shares
MetLife Investment Management, LLC $1,820,267 48,840 0.07% Shares
Phocas Financial Corp. $1,819,596 48,822 0.07% Shares

Company insiders 7 insiders · 1 officers · 6 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Briseno Andres Ruiz Chief Accounting Officer July 7, 2026 M 26,466 0 1 $-382,096
Malcolm Garret Hampton Director June 16, 2026 A 0 0 $0
Scott W Morrison Director June 16, 2026 A 0 0 $0
Catherine J Mackey Director June 16, 2026 A 0 0 $0
Jeffrey Stein Director June 16, 2026 A 0 0 $0
Terry J Rosen Director June 16, 2026 A 0 0 $0
Wendy L Yarno Director June 16, 2026 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
5AM Ventures IV, L.P., 5AM Co-Investors IV, L.P., 5AM Partners IV, LLC, 5AM Opportunities I, L.P., 5AM Opportunities I (GP), LLC, Dr. John D. Diekman, Andrew J. Schwab, Dr. Scott M. Rocklage ×4 filings Aug. 11, 2021 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 58 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
CANC · Tema ETF Trust 2.27% 135,847 NS May 31, 2026 N-PORT
SBIO · ALPS ETF Trust 1.65% 90,520 NS May 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.63% 8,112 NS April 30, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.52% 93,300 NS April 30, 2026 N-PORT
ILDR · First Trust Exchange-Traded Fund VI… 0.45% 43,312 NS May 31, 2026 N-PORT
FYC · First Trust Exchange-Traded AlphaDE… 0.39% 140,187 NS April 30, 2026 N-PORT
FYX · First Trust Exchange-Traded AlphaDE… 0.20% 83,341 NS April 30, 2026 N-PORT
AVSC · AMERICAN CENTURY ETF TRUST 0.20% 184,846 NS May 31, 2026 N-PORT
BIB · ProShares Trust 0.13% 3,246 NS May 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.13% 32,474 NS April 30, 2026 N-PORT
GINN · Goldman Sachs ETF Trust 0.12% 8,889 NS May 31, 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0.11% 2,925 NS April 30, 2026 N-PORT
FSMD · FIDELITY COVINGTON TRUST 0.10% 81,937 NS April 30, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.08% 13,071 NS April 30, 2026 N-PORT
RSSL · Global X Funds 0.07% 36,699 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.06% 3,986 NS May 31, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.06% 278,313 NS April 30, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.05% 423,102 NS May 31, 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0.05% 17,521 NS May 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.04% 36,855 NS April 30, 2026 N-PORT
UWM · ProShares Trust 0.04% 3,117 NS May 31, 2026 N-PORT
URTY · ProShares Trust 0.03% 3,151 NS May 31, 2026 N-PORT
TILT · FlexShares Trust 0.02% 14,784 NS April 30, 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0.01% 3,303 NS May 31, 2026 N-PORT
DXUV · Dimensional ETF Trust 0.01% 1,630 NS April 30, 2026 N-PORT
HDG · ProShares Trust 0.01% 79 NS May 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.01% 10,987 NS April 30, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.01% 129,589 NS April 30, 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0.01% 30,205 NS May 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.01% 23,436 NS April 30, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 24,537 NS April 30, 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0.00% 50,817 NS May 31, 2026 N-PORT
AVUS · AMERICAN CENTURY ETF TRUST 0.00% 12,633 NS May 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTI · VANGUARD INDEX FUNDS July 15, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND July 30, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS July 15, 2026 Daily
ITOT · iShares Trust Aug. 5, 2026 Daily
IWV · iShares Trust Aug. 18, 2026 Daily
IWN · iShares Trust Aug. 17, 2026 Daily
IWO · iShares Trust Aug. 18, 2026 Daily
IWM · iShares Trust Aug. 18, 2026 Daily
IBB · iShares Trust Aug. 18, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust July 23, 2026 Daily
OMFS · Invesco Exchange-Traded Self-Indexe… July 16, 2026 Daily
VHT · VANGUARD WORLD FUND July 20, 2026 Daily
ISCB · iShares Trust Aug. 5, 2026 Daily