DNLI Denali Therapeutics Inc. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 6, 2026
$20.00
· of 52w range
· above low
· to high
$13.7552w low
$27.3052w high
Market Cap (MRQ)
$3.20B
P/E
-6.8
EPS
$-2.97
Revenue
$0
your badges
52W Range
$14–$27
Analyst Rating
BUY
Price Target
$36
P/E
-6.8
ROE
-50.2%
Net Profit Margin
·
Your badge strip is empty — pin a metric anywhere on this page.
DNLI Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$20.00
Market Cap (MRQ)
$3.20B
P/E
-6.8
EPS
$-2.97
Revenue
$0
ROE
-50.2%
52W Range
$14–$27
DNLI Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
range
bars
Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.
10-Year Performance Revenue, net income, margins and EPS trends
Revenue$02016-12-31 → 2025-12-31
EPS$-2.972018-12-31 → 2025-12-31
Free Cash Flow$-422M2018-12-31 → 2025-12-31
Net margin·2018-12-31 → 2023-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | DNLI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -6.85Y avg ≈-12.6 | ≈-12.6 | · | · | |
| P/B (MRQ) | 3.85Y avg ≈3.4 | ≈3.4 | 4.2 | Pricier | |
| Price / FCF (TTM) | -7.35Y avg ≈-12.3 | ≈-12.3 | · | · | |
| Price / Cash Flow (TTM) | -7.45Y avg ≈-12.9 | ≈-12.9 | · | · | |
| Price / Tangible Book (MRQ) | 4.05Y avg ≈3.4 | ≈3.4 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | DNLI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -40.7%5Y avg ≈-25.5% | ≈-25.5% | -7.4% | Weak | |
| ROE | -50.2%5Y avg ≈-32.3% | ≈-32.3% | -8.3% | Weak |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | DNLI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 8.45Y avg ≈7.5 | ≈7.5 | 6.5 | Strong liquidity | |
| Quick Ratio (MRQ) | 7.95Y avg ≈7.2 | ≈7.2 | 5.0 | Strong liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
| Metric | 5Y trend | DNLI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Revenue YoY | 204.7%5Y avg ≈80.7% | ≈80.7% | · | · | |
| Revenue CAGR 3Y | -0.51% | · | · | · |
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
| Metric | 5Y trend | DNLI | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Asset Turnover | 0.05Y avg ≈0.1 | ≈0.1 | 0.2 | Weak | |
| Revenue / Employee | ≈$0.00 | · | · | · |
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.52%
Next Report
Nov 04, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 10, 2026 | $-0.68 | $-0.67 | -1.5% |
| March 31, 2026 | $-0.69 | $-0.74 | 6.8% | |
| Dec. 31, 2025 | $-0.73 | $-0.76 | 3.8% | |
| Sept. 30, 2025 | $-0.74 | $-0.77 | 3.5% | |
| June 30, 2025 | $-0.72 | $-0.73 | 1.9% | |
| March 31, 2025 | $-0.78 | $-0.70 | -11.4% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $331M | $108M | $49M | $336M | $27M | $129M | $0 | |
| R&D Expense | $419M | $396M | $424M | $359M | $265M | $213M | $193M | $143M | $74M | |
| SG&A Expense | $137M | $105M | $103M | $90M | $79M | $60M | $46M | $32M | $16M | |
| Operating Expenses | $555M | $502M | $527M | $449M | $344M | $273M | $240M | $176M | $90M | |
| Operating Income | $-555M | $-487M | $-197M | $-341M | $-296M | $63M | $-213M | $-46M | $-90M | |
| Other Non-op | · | · | $52M | $15M | $5M | $9M | $15M | $10M | $2M | |
| Income Tax | $102.0K | $68.0K | $30.0K | $21.0K | $-575.0K | $823.0K | $-351.0K | $0 | $0 | |
| Net Income | $-513M | $-423M | $-145M | $-326M | $-291M | $71M | $-198M | $-36M | $-88M | |
| EPS (Basic) | $-2.97 | $-2.57 | $-1.06 | $-2.60 | $-2.39 | $0.65 | $-2.07 | $-0.39 | · | |
| EPS (Diluted) | $-2.97 | $-2.57 | $-1.06 | $-2.60 | $-2.39 | $0.63 | $-2.07 | $-0.39 | · | |
| Shares (Basic) | 172,649,097 | 164,473,772 | 137,370,897 | 125,530,703 | 121,524,795 | 108,974,137 | 95,608,208 | 92,621,991 | · | |
| Shares (Diluted) | 172,649,097 | 164,473,772 | 137,370,897 | 125,530,703 | 121,524,795 | 112,703,108 | 95,608,208 | 92,621,991 | · | |
| EBITDA | $-544M | $-480M | $-180M | $-330M | $-287M | $71M | $-205M | $-39M | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $205M | $175M | $127M | $218M | $293M | $507M | $79M | $77M | $218M | |
| Short-term Investments | $663M | $657M | $907M | $1.12B | $572M | $963M | $336M | $387M | $188M | |
| Receivables | $0 | · | · | · | · | $9M | · | · | · | |
| Inventory | $0 | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $33M | $32M | $30M | $36M | $31M | $20M | $15M | $17M | $3M | |
| Current Assets | $901M | $864M | $1.06B | $1.37B | $897M | $1.50B | $430M | $481M | $410M | |
| PP&E (Net) | $52M | $55M | $46M | $44M | $39M | $41M | $47M | $25M | $15M | |
| PP&E (Gross) | $115M | $107M | $92M | $81M | $68M | $62M | $59M | $37M | $20M | |
| Accum. Depreciation | $63M | $52M | $46M | $37M | $29M | $21M | $12M | $12M | $5M | |
| Intangibles | $0 | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $26M | $25M | $18M | $13M | $12M | $2M | $3M | $8M | $1M | |
| Total Assets | $1.14B | $1.37B | $1.15B | $1.46B | $1.40B | $1.60B | $553M | $662M | $487M | |
| Accounts Payable | $505.0K | $11M | $9M | $3M | $5M | $1M | $3M | $2M | $3M | |
| Accrued Liabilities | $98M | $91M | $68M | $67M | · | $8M | $7M | $9M | $5M | |
| Current Liabilities | $98M | $102M | $78M | $364M | $378M | $72M | $45M | $33M | $14M | |
| Capital Leases | $27M | $37M | $45M | $53M | $59M | $64M | $69M | · | · | |
| Other Non-current Liabilities | · | · | $0 | $379.0K | $379.0K | $701.0K | $379.0K | $471.0K | $467.0K | |
| Total Liabilities | $131M | $144M | $123M | $418M | $442M | $454M | $158M | $115M | $21M | |
| Common Stock | · | · | $2M | $2M | $2M | $2M | $1M | $1M | $1M | |
| Paid-in Capital | $3.06B | $2.76B | $2.14B | $2.02B | $1.61B | $1.50B | $819M | $774M | $657M | |
| Retained Earnings | $-2.05B | $-1.54B | $-1.12B | $-971M | $-645M | $-354M | $-426M | $-228M | $-192M | |
| AOCI | $682.0K | $2M | $643.0K | $-7M | $-2M | $-245.0K | $350.0K | $-649.0K | $-368.0K | |
| Stockholders' Equity | $1.01B | $1.23B | $1.03B | $1.04B | $962M | $1.15B | $395M | $547M | $466M | |
| Liabilities + Equity | $1.14B | $1.37B | $1.15B | $1.46B | $1.40B | $1.60B | $553M | $662M | $487M | |
| Shares Outstanding | 156,182,177 | 144,220,986 | 138,385,498 | 135,965,918 | 122,283,305 | 120,531,333 | 96,189,935 | 94,662,435 | 87,480,362 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $11M | $8M | $17M | $10M | $9M | $9M | $8M | $7M | $3M | |
| Stock-based Comp | $100M | $103M | $108M | $100M | $85M | $50M | $38M | $19M | $4M | |
| Deferred Tax | $0 | $0 | $0 | $0 | $0 | $0 | $-351.0K | · | · | |
| Other Non-cash | $-11M | $-36M | $-338M | $-29M | $-15M | $286M | $-331.0K | $60M | · | |
| Operating Cash Flow | $-413M | $-348M | $-358M | $-245M | $-211M | $416M | $-152M | $50M | $-77M | |
| CapEx | $10M | $16M | $13M | $18M | $8M | $3M | $18M | $3M | $3M | |
| Investing Cash Flow | $255M | $-89M | $249M | $-141M | $-22M | $-623M | $148M | $-287M | $-41M | |
| Stock Issued | · | $0 | $0 | $296M | $0 | $194M | $0 | $0 | $266M | |
| Net Stock Activity | · | $0 | $0 | $296M | $0 | $194M | $0 | $0 | · | |
| Financing Cash Flow | $189M | $484M | $18M | $311M | $19M | $635M | $6M | $97M | $296M | |
| Net Change in Cash | $32M | $48M | $-91M | $-75M | $-214M | $428M | · | · | · | |
| Taxes Paid | $46.0K | $0 | $3.0K | $47.0K | $210.0K | $0 | · | · | · | |
| Free Cash Flow | $-422M | $-364M | $-371M | $-263M | $-220M | $413M | $-169M | $47M | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | -59.5% | -314.2% | -607.8% | 18.7% | -799.1% | -35.9% | · | |
| Net Margin | · | · | -43.9% | -300.6% | -597.1% | 21.2% | -740.7% | -28.1% | · | |
| EBITDA Margin | · | · | -54.4% | -304.6% | -590.1% | 21.2% | -769.1% | -30.2% | · | |
| ROA | -40.7% | -33.5% | -11.1% | -22.8% | -19.3% | 6.6% | -32.5% | -6.3% | · | |
| ROE | -50.2% | -33.2% | -13.5% | -35.2% | -29.4% | 7.0% | -47.4% | -7.2% | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 9.2 | 8.5 | 13.6 | 3.8 | 2.4 | 20.9 | 9.5 | 14.7 | · | |
| Quick Ratio | 8.8 | 8.1 | 13.3 | 3.7 | 2.3 | 20.5 | 9.2 | 14.2 | · |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.3 | 0.1 | 0.0 | 0.3 | 0.0 | 0.2 | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $6.49 | $8.53 | $7.45 | $7.67 | $7.87 | $9.55 | $4.11 | $5.78 | · | |
| Revenue / Share | $0.00 | $0.00 | $2.41 | $0.86 | $0.40 | $2.98 | · | · | · | |
| Cash Flow / Share | $-2.39 | $-2.11 | $-2.61 | $-1.95 | $-1.74 | $3.69 | · | · | · | |
| Cash / Share | $1.31 | $1.21 | $0.92 | $1.60 | $2.40 | $4.21 | $0.83 | $0.81 | · | |
| EPS (TTM) | $-2.97 | $-2.57 | $-1.06 | $-2.60 | $-2.39 | $0.63 | $-2.07 | $-0.39 | · |
Growth Rates
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | 204.7% | 122.9% | -85.5% | · | · | · | · | |
| Revenue CAGR 3Y | · | · | -0.51% | · | · | · | · | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $0 | $331M | $108M | $49M | $336M | $27M | $129M | $0 | |
| Net Income TTM | $-513M | $-423M | $-145M | $-326M | $-291M | $71M | $-198M | $-36M | $-88M | |
| Market Cap | $2.58B | $2.94B | $2.97B | $3.78B | $5.45B | $10.10B | $1.68B | $1.96B | · | |
| P/E | -5.6 | -7.9 | -20.2 | -10.7 | -18.7 | 133.0 | -8.4 | -53.0 | · | |
| P/S | · | · | 9.0 | 34.9 | 112.1 | 30.1 | 62.8 | 15.1 | · | |
| P/B | 2.5 | 2.4 | 2.9 | 3.6 | 5.7 | 8.8 | 4.2 | 3.6 | · | |
| P / Tangible Book | 2.5 | 2.4 | 2.9 | 3.6 | 5.7 | 8.8 | · | · | · | |
| P / Cash Flow | -6.2 | -8.5 | -8.3 | -15.5 | -25.8 | 24.3 | -11.1 | 39.0 | · | |
| P / FCF | -6.1 | -8.1 | -8.0 | -14.4 | -24.8 | 24.4 | -9.9 | 41.9 | · | |
| Earnings Yield | -18.0% | -12.6% | -4.9% | -9.3% | -5.4% | 0.75% | -11.9% | -1.9% | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $4M | · | · | · | $0 | · | $0 | $0 | $0 | $0 | $1M | $294M | $35M | $4M | $52M | $42M | |
| Cost of Revenue | $93.0K | · | · | · | $0 | · | · | · | · | · | · | · | · | · | · | · | |
| R&D Expense | $97M | $104M | $98M | $102M | $103M | $116M | $100M | $98M | $91M | $107M | $90M | $98M | $129M | $88M | $93M | $86M | |
| SG&A Expense | $36M | $34M | $39M | $35M | $32M | $29M | $30M | $25M | $25M | $25M | $25M | $26M | $27M | $23M | $21M | $23M | |
| Operating Expenses | $134M | $137M | $137M | $137M | $135M | $146M | $130M | $123M | $117M | $132M | $115M | $124M | $156M | $111M | $114M | $109M | |
| Operating Income | $-131M | $-137M | $-137M | $-137M | $-135M | $-146M | $-130M | $-123M | $-117M | $-118M | $-114M | $170M | $-121M | $-107M | $-61M | $-66M | |
| Other Non-op | · | · | · | · | · | · | · | · | · | · | $14M | $13M | $11M | $4M | $3M | $1M | |
| Income Tax | · | · | · | · | · | · | · | · | · | · | $0 | $0 | · | $0 | $27.0K | · | |
| Net Income | $-128M | $-128M | $-129M | $-127M | $-124M | $-133M | $-115M | $-107M | $-99M | $-102M | $-99M | $183M | $-110M | $-103M | $-59M | $-65M | |
| EPS (Basic) | $-0.68 | $-0.69 | $-0.73 | $-0.74 | $-0.72 | $-0.78 | $-0.67 | $-0.63 | $-0.59 | $-0.68 | $-0.72 | $1.34 | $-0.80 | $-0.84 | $-0.48 | $-0.53 | |
| EPS (Diluted) | $-0.68 | $-0.69 | $-0.73 | $-0.74 | $-0.72 | $-0.78 | $-0.67 | $-0.63 | $-0.59 | $-0.68 | $-0.72 | $1.30 | $-0.80 | $-0.84 | $-0.48 | $-0.53 | |
| Shares (Basic) | 187,314,501 | 186,636,978 | · | 172,421,492 | 171,449,847 | 171,222,030 | · | 169,456,988 | 168,831,329 | 149,404,188 | 137,644,534 | 137,047,227 | 136,524,528 | 123,473,390 | 123,008,558 | 122,673,935 | |
| Shares (Diluted) | 187,314,501 | 186,636,978 | · | 172,421,492 | 171,449,847 | 171,222,030 | · | 169,456,988 | 168,831,329 | 149,404,188 | 137,644,534 | 140,930,625 | 136,524,528 | 123,473,390 | 123,008,558 | 122,673,935 | |
| EBITDA | $-131M | $-135M | · | $-137M | $-135M | $-143M | · | $-123M | $-117M | $-116M | $-114M | $170M | $-111M | $-107M | $-61M | $-64M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $202M | $388M | $205M | $91M | $141M | $57M | $175M | $91M | $75M | $61M | $148M | $132M | $68M | $119M | $155M | $105M | |
| Short-term Investments | $509M | $600M | $663M | $757M | $758M | $761M | $657M | $746M | $821M | $876M | $961M | $1.06B | $1.22B | $987M | $914M | $853M | |
| Receivables | $4M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Inventory | $4M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $35M | $35M | $33M | $34M | $36M | $61M | $32M | $32M | $32M | $37M | $34M | $33M | $37M | $32M | $46M | $31M | |
| Current Assets | $754M | $1.02B | $901M | $883M | $935M | $879M | $864M | $869M | $928M | $974M | $1.14B | $1.22B | $1.33B | $1.14B | $1.11B | $988M | |
| PP&E (Net) | $50M | $52M | $52M | $54M | $59M | $58M | $55M | $51M | $48M | $47M | $48M | $40M | $42M | $42M | $39M | $38M | |
| PP&E (Gross) | · | · | $115M | · | · | · | $107M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $63M | · | · | · | $52M | · | · | · | · | · | · | · | · | · | |
| Intangibles | $35M | $36M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Other Non-current Assets | $26M | $26M | $26M | $25M | $23M | $27M | $25M | $26M | $51M | $45M | $11M | $14M | $14M | $16M | $15M | $14M | |
| Total Assets | $1.16B | $1.27B | $1.14B | $1.06B | $1.17B | $1.27B | $1.37B | $1.45B | $1.50B | $1.58B | $1.24B | $1.31B | $1.41B | $1.23B | $1.29B | $1.32B | |
| Accounts Payable | $12M | $40M | $3M | $7M | $11M | $8M | $11M | $10M | $14M | $12M | · | · | · | $8M | $7M | $3M | |
| Accrued Liabilities | $78M | $70M | $95M | $5M | $7M | $7M | $91M | $5M | $6M | $6M | · | · | · | · | · | · | |
| Current Liabilities | $90M | $110M | $98M | $90M | $91M | $92M | $102M | $87M | $75M | $83M | $71M | $69M | $391M | $361M | $348M | $341M | |
| Capital Leases | $22M | $25M | $27M | $30M | $32M | $34M | $37M | $39M | $41M | $43M | $47M | $49M | $51M | $55M | $56M | $57M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | $379.0K | $379.0K | $379.0K | $379.0K | $379.0K | $379.0K | |
| Total Liabilities | $323M | $340M | $131M | $129M | $139M | $149M | $144M | $136M | $116M | $126M | $118M | $119M | $443M | $416M | $408M | $403M | |
| Common Stock | · | · | · | · | · | · | · | · | · | · | $2M | $2M | $2M | $2M | $2M | $2M | |
| Paid-in Capital | $3.14B | $3.10B | $3.06B | $2.85B | $2.82B | $2.79B | $2.76B | $2.74B | $2.70B | $2.67B | $2.11B | $2.08B | $2.05B | $1.69B | $1.66B | $1.64B | |
| Retained Earnings | $-2.31B | $-2.18B | $-2.05B | $-1.92B | $-1.80B | $-1.67B | $-1.54B | $-1.42B | $-1.32B | $-1.22B | $-997M | $-897M | $-1.08B | $-872M | $-769M | $-710M | |
| AOCI | $-2M | $-682.0K | $682.0K | $1M | $939.0K | $2M | $2M | $6M | $-3M | $-1M | $-651.0K | $-1M | $-3M | $-12M | $-12M | $-9M | |
| Stockholders' Equity | $835M | $926M | $1.01B | $926M | $1.03B | $1.12B | $1.23B | $1.32B | $1.39B | $1.46B | $1.12B | $1.19B | $967M | $811M | $884M | $918M | |
| Liabilities + Equity | $1.16B | $1.27B | $1.14B | $1.06B | $1.17B | $1.27B | $1.37B | $1.45B | $1.50B | $1.58B | $1.24B | $1.31B | $1.41B | $1.23B | $1.29B | $1.32B | |
| Shares Outstanding | 159,755,526 | 158,656,318 | 156,182,177 | 146,625,722 | 145,685,442 | 145,251,258 | 144,220,986 | 143,840,029 | 143,123,582 | 142,512,856 | 138,051,798 | 137,362,688 | 136,741,627 | 123,796,438 | 123,157,278 | 122,857,908 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $4M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $10M | $2M | $2M | $2M | |
| Stock-based Comp | $23M | $23M | $24M | $25M | $25M | $25M | $25M | $25M | $25M | $28M | $27M | $27M | $28M | $25M | $24M | $26M | |
| Amort. of Intangibles | $750.0K | · | · | · | $0 | · | · | · | · | · | · | · | · | · | · | · | |
| Other Non-cash | · | $-29M | · | · | · | $-26M | · | · | · | $-42M | · | · | $13M | · | · | $-35M | |
| Operating Cash Flow | $-97M | $-131M | $-99M | $-107M | $-75M | $-131M | $-84M | $-59M | $-91M | $-114M | $-87M | $-113M | $-59M | $-57M | $-43M | $-72M | |
| CapEx | $805.0K | $2M | $2M | $-1M | $4M | $5M | $5M | $4M | $5M | $2M | $2M | $6M | $3M | $6M | $3M | $4M | |
| Investing Cash Flow | $-104M | $94M | $21M | $58M | $158M | $19M | $172M | $94M | $99M | $-453M | $101M | $168M | $-93M | $15M | $89M | $-118M | |
| Stock Issued | $0 | $12M | · | $0 | $0 | $0 | · | $0 | $0 | $499M | $0 | $0 | $0 | · | · | · | |
| Net Stock Activity | · | $12M | · | · | · | $0 | · | · | · | $499M | · | · | · | · | · | · | |
| Financing Cash Flow | $15M | $219M | $192M | $-778.0K | $2M | $-4M | $-4M | $-19M | $7M | $500M | $2M | $9M | $2M | $5M | $4M | $1M | |
| Net Change in Cash | $-186M | $182M | $114M | $-50M | $84M | $-116M | $84M | $16M | $14M | $-67M | $16M | $64M | $-150M | $-36M | $50M | $-189M | |
| Taxes Paid | · | · | · | · | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $4.0K | $0 | $0 | $0 | |
| Free Cash Flow | · | $-134M | · | · | · | $-137M | · | · | · | $-116M | · | · | $-62M | · | · | $-76M |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -3622.1% | · | · | · | · | · | · | · | · | · | -8981.4% | 58.0% | -343.8% | -3020.1% | -117.0% | -157.8% | |
| Net Margin | -3539.2% | · | · | · | · | · | · | · | · | · | -7841.6% | 62.4% | -312.4% | -2902.5% | -112.0% | -154.8% | |
| EBITDA Margin | -3622.1% | · | · | · | · | · | · | · | · | · | -8981.4% | 58.0% | -315.2% | -3020.1% | -117.0% | -152.9% | |
| ROA | -11.0% | -10.1% | · | -10.1% | -9.3% | -9.3% | · | -8.0% | -7.0% | -6.8% | -8.1% | 14.1% | -8.0% | -7.7% | -4.2% | -4.5% | |
| ROE | -13.7% | -12.5% | · | -11.3% | -10.3% | -10.3% | · | -8.8% | -7.7% | -8.4% | -10.3% | 17.7% | -11.7% | -11.3% | -6.0% | -6.5% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 8.4 | 9.3 | · | 9.8 | 10.3 | 9.6 | · | 10.0 | 12.5 | 11.8 | 16.1 | 17.6 | 3.4 | 3.2 | 3.2 | 2.9 | |
| Quick Ratio | 7.9 | 9.0 | · | 9.4 | 9.9 | 8.9 | · | 9.6 | 12.0 | 11.3 | 15.6 | 17.2 | 3.3 | 3.1 | 3.1 | 2.8 |
Efficiency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | · | · | · | · | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | 0.0 | 0.0 | 0.0 | 0.0 | |
| Inventory Turnover | 0.0 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Receivables Turnover | 0.4 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $5.23 | $5.84 | · | $6.32 | $7.05 | $7.73 | · | $9.17 | $9.69 | $10.21 | $8.10 | $8.64 | $7.07 | $6.55 | $7.18 | $7.47 | |
| Revenue / Share | $0.02 | · | · | · | · | · | · | $0.00 | $0.00 | $0.00 | $0.01 | $2.09 | $0.26 | $0.03 | $0.43 | $0.34 | |
| Cash Flow / Share | · | $-0.70 | · | · | · | $-0.77 | · | · | · | $-0.76 | · | · | $-0.43 | · | · | $-0.59 | |
| Cash / Share | $1.26 | $2.44 | · | $0.62 | $0.97 | $0.39 | · | $0.63 | $0.52 | $0.42 | $1.07 | $0.96 | $0.50 | $0.96 | $1.26 | $0.85 | |
| EPS (TTM) | $-2.84 | $-2.88 | · | $-2.91 | $-2.80 | $-2.67 | · | $-2.74 | $-2.83 | $-0.94 | $-0.97 | $-1.09 | $-2.87 | $-2.47 | $-2.32 | $-2.34 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | · | · | · | · | · | $0 | · | $0 | $1M | $295M | $341M | $343M | $101M | $111M | $112M | $83M | |
| Net Income TTM | $-511M | $-508M | · | $-499M | $-479M | $-454M | · | $-427M | $-420M | $-137M | $-124M | $-128M | $-371M | $-303M | $-284M | $-286M | |
| Market Cap | $4.11B | $3.05B | · | $2.13B | $2.04B | $1.97B | · | $4.19B | $3.32B | $2.92B | $2.85B | $4.05B | $3.15B | $3.80B | $3.62B | $3.95B | |
| P/E | -9.1 | -6.7 | · | -5.0 | -5.0 | -5.1 | · | -10.6 | -8.2 | -21.8 | -21.3 | -27.1 | -8.0 | -12.4 | -12.7 | -13.7 | |
| P/S | · | · | · | · | · | · | · | · | 2623.0 | 9.9 | 8.4 | 11.8 | 31.1 | 34.3 | 32.2 | 47.7 | |
| P/B | 4.9 | 3.3 | · | 2.3 | 2.0 | 1.8 | · | 3.2 | 2.4 | 2.0 | 2.5 | 3.4 | 3.3 | 4.7 | 4.1 | 4.3 | |
| P / Tangible Book | 5.1 | 3.4 | · | 2.3 | 2.0 | 1.8 | · | 3.2 | 2.4 | 2.0 | 2.5 | 3.4 | 3.3 | 4.7 | 4.1 | 4.3 | |
| P / Cash Flow | · | -23.2 | · | · | · | -15.0 | · | · | · | -25.7 | · | · | -53.6 | · | · | -54.8 | |
| Earnings Yield | -11.0% | -15.0% | · | -20.0% | -20.0% | -19.6% | · | -9.4% | -12.2% | -4.6% | -4.7% | -3.7% | -12.5% | -8.1% | -7.9% | -7.3% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $331M | $108M | $49M |
| Operating Margin % | · | · | -59.5% | -314.2% | -607.8% |
| Net Income | $-513M | $-423M | $-145M | $-326M | $-291M |
| Diluted EPS | $-2.97 | $-2.57 | $-1.06 | $-2.60 | $-2.39 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Current Ratio | 9.2 | 8.5 | 13.6 | 3.8 | 2.4 |
| Quick Ratio | 8.8 | 8.1 | 13.3 | 3.7 | 2.3 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | $-422M | $-364M | $-371M | $-263M | $-220M |
Institutional owners (13F) 315 filers · $3.8B total · As of Sept. 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
315
Value held
$3.8B
New positions
55
Exited positions
27
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 55 (-11 vs prior Q) | 27 (+1 vs prior Q) | 123 (+18 vs prior Q) | 68 (+11 vs prior Q) | +6.1M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| BlackRock, Inc. | $360,759,342 | 14,026,413 | 9.60% | Shares |
| BAILLIE GIFFORD & CO | $307,617,116 | 11,960,230 | 8.18% | Shares |
| VANGUARD GROUP INC | $215,585,764 | 13,057,890 | 5.74% | Shares |
| STATE STREET CORP | $181,308,099 | 7,049,304 | 4.82% | Shares |
| Temasek Holdings (Private) Ltd | $180,373,691 | 7,012,974 | 4.80% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $166,589,906 | 6,477,057 | 4.43% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $161,411,750 | 6,275,729 | 4.29% | Shares |
| FMR LLC | $116,661,699 | 4,535,836 | 3.10% | Shares |
| GOLDMAN SACHS GROUP INC | $106,889,625 | 4,155,895 | 2.84% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $102,212,911 | 3,973,342 | 2.72% | Shares |
| Holocene Advisors, LP | $100,442,387 | 3,905,225 | 2.67% | Shares |
| BAKER BROS. ADVISORS LP | $96,047,122 | 3,734,336 | 2.56% | Shares |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $85,100,430 | 4,432,314 | 2.26% | Shares |
| UBS Group AG | $80,261,627 | 3,120,592 | 2.14% | Shares |
| DIMENSIONAL FUND ADVISORS LP | $73,575,277 | 2,860,604 | 1.96% | Shares |
| NORGES BANK | $72,652,467 | 2,824,746 | 1.93% | Shares |
| Pictet Asset Management Holding SA | $71,894,854 | 2,791,206 | 1.91% | Shares |
| Capital Research Global Investors | $65,992,813 | 2,565,817 | 1.76% | Shares |
| Fisher Asset Management, LLC | $62,092,245 | 2,414,162 | 1.65% | Shares |
| ALLIANCEBERNSTEIN L.P. | $57,308,294 | 2,984,807 | 1.52% | Shares |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $56,797,000 | 2,208,263 | 1.51% | Shares |
| Casdin Capital, LLC | $52,597,400 | 2,045,000 | 1.40% | Shares |
| Crestline Management, L.P. | $49,144,027 | 1,910,732 | 1.31% | Shares |
| PRINCIPAL FINANCIAL GROUP INC | $36,524,535 | 1,420,083 | 0.97% | Shares |
| Foresite Capital Management VI LLC | $35,924,950 | 1,396,771 | 0.96% | Shares |
| Siren, L.L.C. | $35,918,314 | 1,396,513 | 0.96% | Shares |
| NORTHERN TRUST CORP | $35,744,756 | 1,389,765 | 0.95% | Shares |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $34,863,820 | 1,355,514 | 0.93% | Shares |
| Aberdeen Group plc | $34,605,771 | 1,345,481 | 0.92% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $32,020,243 | 1,244,955 | 0.85% | Shares |
| BANK OF AMERICA CORP /DE/ | $31,660,215 | 1,230,957 | 0.84% | Shares |
| Artisan Partners Limited Partnership | $31,494,063 | 1,224,497 | 0.84% | Shares |
| Candriam S.C.A. | $30,574,423 | 1,189,886 | 0.81% | Shares |
| MILLENNIUM MANAGEMENT LLC | $28,954,239 | 1,125,748 | 0.77% | Shares |
| ADAR1 Capital Management, LLC | $26,467,938 | 1,029,080 | 0.70% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $25,511,771 | 991,904 | 0.68% | Shares |
| MORGAN STANLEY | $24,718,235 | 961,050 | 0.66% | Shares |
| Bank of New York Mellon Corp | $20,583,293 | 800,283 | 0.55% | Shares |
| DAFNA Capital Management LLC | $19,007,440 | 739,014 | 0.51% | Shares |
| AMERICAN CENTURY COMPANIES INC | $18,326,346 | 712,526 | 0.49% | Shares |
| Cercano Management LLC | $16,075,000 | 625,000 | 0.43% | Shares |
| Nuveen, LLC | $15,662,631 | 608,967 | 0.42% | Shares |
| Ensign Peak Advisors, Inc | $14,986,247 | 582,669 | 0.40% | Shares |
| MARSHALL WACE, LLP | $14,141,627 | 549,830 | 0.38% | Shares |
| SEGALL BRYANT & HAMILL, LLC | $13,361,103 | 519,483 | 0.36% | Shares |
| CITIGROUP INC | $12,532,790 | 487,278 | 0.33% | Shares |
| CITADEL ADVISORS LLC | $11,723,176 | 455,800 | 0.31% | Put option |
| Balyasny Asset Management L.P. | $11,131,616 | 432,800 | 0.30% | Call option |
| Defilade Capital Management, L.P. | $10,078,794 | 391,866 | 0.27% | Shares |
| AQR CAPITAL MANAGEMENT LLC | $9,991,416 | 388,469 | 0.27% | Shares |
Company insiders 18 insiders · 4 officers · 13 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Ryan J. Watts | President and CEO | Aug. 12, 2026 G | 2,120,384 | 0 | 1 | $-580,767 |
| Peter Scott Chin | Chief Medical Officer | Sept. 4, 2026 S | 204,538 | 0 | 1 | $-36,868 |
| Alexander O. Schuth | COFO and Secretary | Sept. 1, 2026 S | 278,995 | 0 | 3 | $-420,604 |
| Carole Ho | Chief Medical Officer | Aug. 13, 2025 S | 216,585 | 0 | 0 | $0 |
| Nancy Thornberry | Director | Sept. 2, 2026 S | 19,686 | 0 | 2 | $-261,928 |
| Timothy Van Hauwermeiren | Director | June 3, 2026 A | 17,040 | 0 | 0 | $0 |
| Jennifer E. Cook | Director | June 3, 2026 A | 32,483 | 0 | 0 | $0 |
| Steve E. Krognes | Director | June 3, 2026 A | 38,202 | 0 | 0 | $0 |
| David P Schenkein | Director | June 3, 2026 A | 21,665 | 0 | 0 | $0 |
| Peter S Klein | Director | June 3, 2026 A | 33,941 | 0 | 0 | $0 |
| Jay T Flatley | Director | June 3, 2026 A | 22,628 | 0 | 0 | $0 |
| Marc Tessier-Lavigne | Director | June 3, 2025 A | 1,886,576 | 0 | 0 | $0 |
| Vicki L Sato | Director | Jan. 2, 2025 S | 107,976 | 0 | 0 | $0 |
| Erik Harris | Director | May 31, 2024 A | 17,052 | 0 | 0 | $0 |
| Douglas G. Cole | Director | June 1, 2023 A | 26,564 | 0 | 0 | $0 |
| Robert Nelsen | Director | June 2, 2021 A | 12,432 | 0 | 0 | $0 |
| FMR LLC | · | April 9, 2018 | · | 0 | 0 | $0 |
| FIL Ltd | · | Dec. 12, 2017 C | 1,379 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 39 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IBRN · iShares Trust | 3.34% | 11,666 SH | Sept. 11, 2026 | Daily |
| BBP · ETFis Series Trust I | 1.46% | 62,658 NS | July 31, 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0.55% | 117,771 NS | July 31, 2026 | N-PORT |
| IBB · iShares Trust | 0.24% | 1,135,594 SH | Sept. 11, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.23% | 121,790 SH | Aug. 19, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0.22% | 11,322 SH | Oct. 2, 2026 | Daily |
| PWS · Pacer Funds Trust | 0.15% | 1,609 NS | July 31, 2026 | N-PORT |
| BKSE · BNY Mellon ETF Trust | 0.15% | 5,790 NS | July 31, 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0.14% | 186,003 SH | Oct. 2, 2026 | Daily |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0.12% | 36,586 NS | July 31, 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.11% | 846,335 SH | Aug. 19, 2026 | Daily |
| RSSL · Global X Funds | 0.11% | 70,425 NS | July 31, 2026 | N-PORT |
| IWM · iShares Trust | 0.10% | 3,761,614 SH | Sept. 11, 2026 | Daily |
| VBK · VANGUARD INDEX FUNDS | 0.09% | 1,784,440 SH | Aug. 19, 2026 | Daily |
| DFAS · Dimensional ETF Trust | 0.07% | 456,915 NS | July 31, 2026 | N-PORT |
| ESML · iShares Trust | 0.06% | 76,805 SH | Sept. 11, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | 0.05% | 405,796 SH | Aug. 19, 2026 | Daily |
| FHLC · FIDELITY COVINGTON TRUST | 0.04% | 64,057 NS | July 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0.04% | 1,731,356 SH | Aug. 19, 2026 | Daily |
| VB · VANGUARD INDEX FUNDS | 0.04% | 3,091,727 SH | Aug. 19, 2026 | Daily |
| WSML · iShares Trust | 0.03% | 7,770 SH | Sept. 11, 2026 | Daily |
| DFAC · Dimensional ETF Trust | 0.01% | 238,844 NS | July 31, 2026 | N-PORT |
| IWO · iShares Trust | 0.01% | 74,347 SH | Sept. 11, 2026 | Daily |
| TILT · FlexShares Trust | 0.01% | 10,428 NS | July 31, 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0.01% | 14,634 NS | July 31, 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.01% | 8,139 SH | Aug. 19, 2026 | Daily |
| ESGV · VANGUARD WORLD FUND | 0.01% | 32,379 SH | Aug. 19, 2026 | Daily |
| DFAU · Dimensional ETF Trust | 0.01% | 38,627 NS | July 31, 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0.01% | 1,615 NS | July 31, 2026 | N-PORT |
| ITOT · iShares Trust | 0.00% | 208,727 SH | Sept. 11, 2026 | Daily |
| IWV · iShares Trust | 0.00% | 41,910 SH | Sept. 10, 2026 | Daily |
| DFUS · Dimensional ETF Trust | 0.00% | 39,869 NS | July 31, 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0.00% | 4,289,786 SH | Aug. 19, 2026 | Daily |
| VT · VANGUARD INTERNATIONAL EQUITY INDEX… | 0.00% | 117,791 SH | Aug. 19, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0.00% | 11,822 SH | Aug. 19, 2026 | Daily |
| IWN · iShares Trust | · | 1,308,489 SH | Sept. 11, 2026 | Daily |
| ISCB · iShares Trust | · | 6,080 SH | Sept. 11, 2026 | Daily |
| ISCV · iShares Trust | · | 29,811 SH | Sept. 11, 2026 | Daily |
| SMLF · iShares Trust | · | 257,359 SH | Sept. 11, 2026 | Daily |
DNLI Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 26 analysts
BUY
Median target
$35.00
+75.0%
11 42.3%
Strong Buy
13 50.0%
Buy
2 7.7%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
16 analysts · 2026-10-02Mean target $36.06 +80.3%
← Below all targets
Current price $20.00
Low$27.00
Mean$36.06
High$42.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| DNLI | $2.58B | -5.6 | 204.7% | · | -50.2% | · |
| CELC | $4.81B | -26.3 | · | · | -244.3% | · |
| PBLS | · | · | · | · | · | · |
| CDNA | $959M | -47.1 | 13.8% | -5.6% | -6.8% | · |
| ACAD | $4.55B | 11.6 | 11.9% | 36.5% | 38.1% | · |
| ARQT | $3.58B | -223.4 | 91.3% | -4.3% | -9.8% | · |
| RCUS | $2.99B | -7.2 | -4.3% | -142.9% | -59.8% | · |
| PGEN | $1.48B | -3.1 | 146.7% | -2588.2% | 3159.1% | · |
| DYN | $3.23B | -5.6 | · | · | -57.8% | · |
| PURR | $1.58B | 2.5 | · | 3229.8% | 24.8% | · |
Latest News Recent headlines mentioning this company
My Metrics Your personal watchlist — selected rows from Full Fundamentals
Pick the metrics that matter to you — click the + next to any row in Full Fundamentals above.
Your selection is saved and follows you across all tickers.
Source: SEC 10-Q filed Aug 6, 2026