CLNN Clene Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$4.11
Price · Aug 19, 2026
Fundamentals as of Aug 14, 2026

CLNN Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$4.11
Market Cap
$45M
P/E (TTM)
EPS (TTM)
Revenue (TTM)
$200.0K
Div Yield
ROE
200.2%
Debt/Equity
52W Range
$4 – $14

CLNN Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $200.0K
6-point trend, -2.9%
2020-12-31 2025-12-31
EPS
Free Cash Flow $-19M
6-point trend, +3.8%
2020-12-31 2025-12-31
Margins -13086.5%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
CLNN
Peer Median
P/S (TTM)
5-point trend, -95.5%
223.0
152.5
P/B
5-point trend, -100.9%
-2.5
2.3
Price / FCF
5-point trend, +97.6%
-2.4

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
CLNN
Peer Median
Operating Margin
5-point trend, -67.0%
-11541.5%
Net Profit Margin
5-point trend, -871.4%
-13086.5%
-7040.5%
ROA
5-point trend, -675.8%
-115.1%
-79.5%
ROE
5-point trend, +287.9%
200.2%
-119.8%
ROIC
5-point trend, +134.5%
131.2%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
CLNN
Peer Median
Current Ratio
5-point trend, -90.8%
0.8
2.8
Quick Ratio
5-point trend, -94.2%
0.5

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
CLNN
Peer Median
Revenue YoY
5-point trend, -72.3%
-41.5%
Revenue CAGR 3Y
5-point trend, -72.3%
-24.9%
Revenue CAGR 5Y
5-point trend, -72.3%
-0.59%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
CLNN
Peer Median

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
CLNN
Peer Median

CLNN Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 11 analysts
  • Strong Buy 2 18.2%
  • Buy 8 72.7%
  • Hold 1 9.1%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

5 analysts · 2026-08-18
Median target $30.00 +629.9%
Mean target $32.20 +683.5%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.08%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.27 $-0.65 0.38%
Dec. 31, 2025 $-0.88 $-0.60 -0.28%
Sept. 30, 2025 $-0.85 $-0.59 -0.26%
June 30, 2025 $-0.78 $-0.48 -0.30%
March 31, 2025 $-0.09 $-0.97 0.88%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CLNN $64M -41.5% -13086.5% 200.2%
BOLD $27M -0.5 -46.7%
HRTX $245M -10.8 7.4% -13.0% 312.5% 73.3%
INMB $41M -0.8 257.1% -91866.0% -175.3%
EXOZ $92M -10.0 -172.3%
INKT -3.8 4.5% -6931.8% 63.4%
RNXT -2.6 2511.6%
XLO $3M -0.2 589.9% -80.0% -165.5%
TCRX -1.0 266.7% -1256.8% -86.6%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for CLNN
Metric Trend 202520242023202220212020
Revenue 6-point trend, -2.9% $200.0K $342.0K $654.0K $473.0K $723.0K $206.0K
Cost of Revenue 5-point trend, -85.1% $43.0K $70.0K $121.0K $26.0K $289.0K ·
R&D Expense 6-point trend, -7.8% $14M $20M $27M $32M $28M $15M
SG&A Expense 6-point trend, +79.2% $9M $13M $14M $17M $22M $5M
Operating Expenses 6-point trend, +14.0% $23M $33M $41M $49M $51M $20M
Operating Income 6-point trend, -14.2% $-23M $-33M $-41M $-48M $-50M $-20M
Interest Expense 4-point trend, +379.8% · · $5M $3M $870.0K $950.0K
Interest Income 4-point trend, -0.9% $223.0K $865.0K $1M $225.0K · ·
Other Non-op 6-point trend, -100.0% $0 $-1.0K $10.0K $32.0K $-12.0K $34.0K
Pretax Income 6-point trend, -38.7% $-26M $-39M $-50M $-30M $-10M $-19M
Income Tax 6-point trend, -100.0% $0 $0 $0 $0 $-428.0K $406.0K
Net Income 6-point trend, -35.8% $-26M $-39M $-50M $-30M $-10M $-19M
EPS (Basic) 5-point trend, -1556.2% $-2.65 $-5.67 $-9.43 $-0.46 $-0.16 ·
Shares (Basic) 5-point trend, -84.0% 9,858,907 6,954,133 5,246,941 65,204,663 61,558,455 ·
EBITDA 6-point trend, -14.2% $-23M $-33M $-41M $-48M $-50M $-20M
Balance Sheet 27
Annual Balance Sheet data for CLNN
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, -91.2% $5M $12M $29M $18M $50M $59M
Short-term Investments 4-point trend, +0.00 · $0 $6M $5M $0 ·
Receivables 6-point trend, -100.0% $0 $64.0K $143.0K $189.0K $49.0K $21.0K
Inventory 6-point trend, -80.6% $37.0K $68.0K $37.0K $43.0K $41.0K $191.0K
Prepaid Expense 6-point trend, +7.1% $4M $4M $4M $6M $4M $4M
Other Current Assets 5-point trend, +5.2% $425.0K $137.0K $568.0K $581.0K $404.0K ·
Current Assets 6-point trend, -85.7% $9M $16M $39M $29M $55M $63M
PP&E (Net) 2-point trend, +22.4% · · · · $5M $4M
PP&E (Gross) 2-point trend, +24.5% · · · · $9M $8M
Accum. Depreciation 2-point trend, +27.2% · · · · $4M $3M
Total Assets 6-point trend, -73.4% $18M $27M $52M $44M $63M $68M
Accounts Payable 6-point trend, -20.6% $892.0K $1M $2M $3M $2M $1M
Accrued Liabilities 6-point trend, +26.3% $5M $8M $4M $4M $4M $4M
Short-term Debt 4-point trend, +359000.00 · $359.0K $15M $6M $0 ·
Current Liabilities 6-point trend, -7.6% $11M $10M $25M $14M $6M $12M
Capital Leases 6-point trend, +82.1% $3M $4M $5M $6M $4M $2M
Deferred Tax 2-point trend, -100.0% · · · · $0 $260.0K
Total Liabilities 6-point trend, -47.4% $36M $36M $39M $41M $50M $68M
Long-term Debt $18M · · · · ·
Total Debt 4-point trend, -93.9% · $359.0K $15M $6M · $6M
Common Stock 6-point trend, -83.3% $1.0K $1.0K $1.0K $7.0K $6.0K $6.0K
Paid-in Capital 6-point trend, +89.2% $291M $273M $256M $196M $176M $154M
Retained Earnings 6-point trend, -100.8% $-308M $-282M $-243M $-193M $-163M $-154M
AOCI 6-point trend, -47.1% $172.0K $71.0K $199.0K $203.0K $233.0K $325.0K
Stockholders' Equity 6-point trend, -5258.9% $-18M $-9M $13M $3M $13M $341.0K
Liabilities + Equity 6-point trend, -73.4% $18M $27M $52M $44M $63M $68M
Shares Outstanding 6-point trend, -81.8% 10,849,974 8,089,565 6,421,084 74,759,591 62,312,097 59,526,171
Cash Flow 11
Annual Cash Flow data for CLNN
Metric Trend 202520242023202220212020
Stock-based Comp 6-point trend, +738.6% $6M $8M $9M $9M $12M $761.0K
Deferred Tax 3-point trend, -100.0% · · · $0 $-282.0K $260.0K
Operating Cash Flow 6-point trend, +2.0% $-19M $-21M $-30M $-39M $-35M $-19M
CapEx 6-point trend, -89.9% $39.0K $15.0K $330.0K $5M $1M $387.0K
Investing Cash Flow 6-point trend, +89.9% $-39.0K $6M $-1M $-10M $-1M $-387.0K
Stock Issued 2-point trend, +11460000.00 · · · $11M $0 ·
Net Stock Activity · · · $11M · ·
Financing Cash Flow 6-point trend, -83.4% $12M $-2M $42M $17M $27M $70M
Net Change in Cash 6-point trend, -113.8% $-7M $-17M $10M $-32M $-9M $50M
Free Cash Flow 6-point trend, +3.8% $-19M $-21M $-31M $-44M $-36M $-19M
Levered FCF 3-point trend, -72.8% · · $-35M · $-37M $-20M
Profitability 7
Annual Profitability data for CLNN
Metric Trend 202520242023202220212020
Operating Margin 6-point trend, -17.6% -11541.5% -9676.3% -6198.8% -10234.5% -6912.6% -9812.6%
Net Margin 6-point trend, -39.8% -13086.5% -11520.5% -7569.4% -6325.2% -1347.2% -9357.8%
Pretax Margin 6-point trend, -42.9% -13086.5% -11520.5% -7569.4% -6325.2% -1406.4% -9160.7%
EBITDA Margin 6-point trend, -17.6% -11541.5% -9676.3% -6198.8% -10234.5% -6912.6% -9812.6%
ROA 6-point trend, -148.2% -115.1% -98.9% -102.2% -55.6% -14.8% -46.4%
ROE 6-point trend, +351.4% 200.2% 607.0% -284.6% 983.8% -106.5% 44.4%
ROIC 6-point trend, +139.8% 131.2% 389.4% -144.7% -501.4% -380.1% -329.6%
Liquidity & Solvency 4
Annual Liquidity & Solvency data for CLNN
Metric Trend 202520242023202220212020
Current Ratio 6-point trend, -84.6% 0.8 1.6 1.5 2.1 9.1 5.4
Quick Ratio 6-point trend, -90.5% 0.5 1.2 1.4 1.7 8.4 5.1
Debt / Equity 4-point trend, -100.2% · -0.0 1.1 2.0 · 17.4
Interest Coverage 3-point trend, +58.2% · · -8.9 · -57.4 -21.3
Efficiency 3
Annual Efficiency data for CLNN
Metric Trend 202520242023202220212020
Asset Turnover 6-point trend, +76.0% 0.0 0.0 0.0 0.0 0.0 0.0
Inventory Turnover 4-point trend, +32.3% 0.8 1.3 3.0 0.6 · ·
Receivables Turnover 5-point trend, -69.7% 6.2 3.3 3.9 4.0 20.7 ·
Per Share 2
Annual Per Share data for CLNN
Metric Trend 202520242023202220212020
Book Value / Share 6-point trend, -28545.6% $-1.62 $-1.09 $0.10 $0.04 $0.20 $0.01
Cash / Share 6-point trend, -52.0% $0.48 $1.50 $0.22 $0.25 $0.81 $1.00
Growth Rates 3
Annual Growth Rates data for CLNN
Metric Trend 202520242023202220212020
Revenue YoY 5-point trend, -116.5% -41.5% -47.7% 38.3% -34.6% 251.0% ·
Revenue CAGR 3Y 3-point trend, -153.1% -24.9% -22.1% 47.0% · · ·
Revenue CAGR 5Y -0.59% · · · · ·
Valuation (TTM) 12
Annual Valuation (TTM) data for CLNN
Metric Trend 202520242023202220212020
Revenue TTM 6-point trend, -2.9% $200.0K $342.0K $654.0K $473.0K $723.0K $206.0K
Net Income TTM 6-point trend, -35.8% $-26M $-39M $-50M $-30M $-10M $-19M
Market Cap 6-point trend, -99.5% $64M $43M $771M $1.50B $5.11B $12.88B
Enterprise Value 4-point trend, -99.8% · $31M $750M $1.48B · $12.83B
P/S 6-point trend, -99.5% 318.4 125.6 1178.2 3161.1 7067.2 62531.4
P/B 6-point trend, -100.0% -3.6 -4.8 57.5 461.9 405.6 37775.6
P / Tangible Book 4-point trend, -99.8% · · 57.5 461.9 405.6 37775.6
P / Cash Flow 6-point trend, +99.5% -3.4 -2.0 -25.5 -38.3 -147.6 -680.5
P / FCF 6-point trend, +99.5% -3.4 -2.0 -25.3 -33.8 -142.1 -666.9
EV / EBITDA 4-point trend, +99.9% · -0.9 -18.5 -30.5 · -634.6
EV / FCF 4-point trend, +99.8% · -1.5 -24.6 -33.5 · -664.1
EV / Revenue 4-point trend, -99.9% · 91.1 1147.0 3125.4 · 62272.4

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $200.0K$342.0K$654.0K$473.0K$723.0K
Operating Margin % -11541.5%-9676.3%-6198.8%-10234.5%-6912.6%
Net Income $-26M$-39M$-50M$-30M$-10M
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity -0.01.12.0
Current Ratio 0.81.61.52.19.1
Quick Ratio 0.51.21.41.78.4
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-19M$-21M$-31M$-44M$-36M

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Institutional owners (13F) 37 filers · $21.3M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
10 (+9 vs prior Q) 2 (0 vs prior Q) 6 (0 vs prior Q) 6 (+4 vs prior Q) +1.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Empery Asset Management, LP $5,641,254 916,532 26.55% Shares
SCOGGIN MANAGEMENT LP $3,693,000 600,000 17.38% Shares
Boxer Capital Management, LLC $2,939,105 477,515 13.83% Shares
Ensign Peak Advisors, Inc $2,142,322 348,062 10.08% Shares
SymBiosis Capital Partners, LLC $2,125,293 431,094 10.00% Shares
VANGUARD CAPITAL MANAGEMENT LLC $2,053,960 333,706 9.67% Shares
GEODE CAPITAL MANAGEMENT, LLC $515,618 83,689 2.43% Shares
VANGUARD FIDUCIARY TRUST CO $355,544 57,765 1.67% Shares
Lunt Capital Management, Inc. $321,660 52,260 1.51% Shares
VANGUARD GROUP INC $256,607 43,715 1.21% Shares
PARSONS CAPITAL MANAGEMENT INC/RI $229,231 37,243 1.08% Shares
PEAK6 LLC $184,724 30,012 0.87% Shares
STATE STREET CORP $183,425 29,801 0.86% Shares
NORTHERN TRUST CORP $121,395 19,723 0.57% Shares
ADAR1 Capital Management, LLC $92,325 15,000 0.43% Shares
Arax Advisory Partners $68,567 11,140 0.32% Shares
PENN DAVIS MCFARLAND INC $67,705 11,000 0.32% Shares
JANE STREET GROUP, LLC $62,799 10,203 0.30% Shares
WELLS FARGO & COMPANY/MN $36,481 5,927 0.17% Shares
Vanguard Global Advisers, LLC $34,523 5,609 0.16% Shares
JONES FINANCIAL COMPANIES LLLP $30,300 5,000 0.14% Shares
ROYAL BANK OF CANADA $18,000 3,000 0.08% Shares
PNC Financial Services Group, Inc. $16,834 2,735 0.08% Shares
Atlantic Private Wealth, LLC $13,572 2,205 0.06% Shares
Steward Partners Investment Advisory, LLC $12,310 2,000 0.06% Shares
BlackRock, Inc. $10,611 1,724 0.05% Shares
OSAIC HOLDINGS, INC. $6,493 1,055 0.03% Shares
SBI Securities Co., Ltd. $6,309 1,025 0.03% Shares
GROUP ONE TRADING LLC $4,222 686 0.02% Shares
Sandy Spring Bank $3,080 1,000 0.01% Shares
UBS Group AG $2,050 333 0.01% Shares
BARCLAYS PLC $1,397 227 0.01% Shares
Lindbrook Capital, LLC $308 100 0.00% Shares
MORGAN STANLEY $160 26 0.00% Shares
US BANCORP \DE\ $123 20 0.00% Shares
HRT FINANCIAL LP $112 18,321 0.00% Shares
BNP PARIBAS FINANCIAL MARKETS $80 13 0.00% Shares

Company insiders 13 insiders · 3 officers · 1 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Robert Dee Etherington President & CEO June 11, 2026 A 0 0 $0
Morgan R Brown Chief Financial Officer June 11, 2026 A 0 0 $0
Mark Mortenson Chief Science Officer June 11, 2026 A 0 0 $0
Matthew Kiernan Aug. 13, 2026 A 0 0 $0
Arjun Jj Desai Aug. 13, 2026 A 0 0 $0
Vallerie Mclaughlin Aug. 13, 2026 A 0 0 $0
Shalom Jacobovitz Aug. 13, 2026 A 0 0 $0
Alison Mosca Aug. 13, 2026 A 280,500 0 0 $0
Jonathon Gay Aug. 13, 2026 A 0 0 $0
Reed N Wilcox Aug. 13, 2026 A 0 0 $0
David J Matlin Aug. 13, 2026 A 0 0 $0
Chidozie Ugwumba July 17, 2026 J 13,018,908 0 0 $0
General Resonance LLC May 16, 2022 S 15,560,212 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 3 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
David J. Matlin ×5 filings Oct. 2, 2024 Initial filing Passive investment SEC
Chidozie Ugwumba ×2 filings Feb. 13, 2023 Initial filing Passive investment SEC
Undisclosed reporting person Jan. 11, 2021 Initial filing M&A / sale SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 3 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
IWC · iShares Trust 0.01% 26,027 SH Aug. 8, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 99,589 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 231,131 SH Aug. 8, 2026 Daily