CNTB Connect Biopharma Holdings Limited - Ordinary Shares
$2.54
Price · Aug 19, 2026
Fundamentals as of Aug 12, 2026
52W Range
$1–$4
50% of range
Analyst Rating
BUY
14 analysts
Price Target
$7
+186% upside
P/E (TTM)
-2.8
ROE
-97.9%
Net Profit Margin
-86687.5%
CNTB Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$2.54
Market Cap
$159M
P/E (TTM)
-2.8
EPS (TTM)
$-1.00
Revenue (TTM)
$64.0K
Div Yield
—
ROE
-97.9%
Debt/Equity
—
52W Range
$1 – $4
CNTB Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
$64.0K
2023-12-31
→
2025-12-31
EPS
$-1.00
2023-12-31
→
2025-12-31
Free Cash Flow
$-52M
2024-12-31
→
2025-12-31
Margins
-86687.5%
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
CNTB
Peer Median
P/E (TTM)
-2.8
1.2
P/S (TTM)
2484.0
14.2
P/B
3.8
1.2
Price / FCF
-3.1
—
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
CNTB
Peer Median
Operating Margin
-90740.6%
—
Net Profit Margin
-86687.5%
-1189.1%
ROA
-70.5%
-58.9%
ROE
-97.9%
-79.0%
ROIC
-138.8%
—
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
CNTB
Peer Median
Current Ratio
3.7
5.4
Quick Ratio
3.3
—
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
CNTB
Peer Median
Revenue YoY
-99.8%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
CNTB
Peer Median
CNTB Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
14 analysts
- Strong Buy 5 35.7%
- Buy 8 57.1%
- Hold 1 7.1%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
8 analysts · 2026-08-17
Median
$7.00
← Below all targets
$2.54
Low
$4.00
High
$10.00
Median target
$7.00
+176.1%
Mean target
$7.25
+186.0%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
1.0%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $-0.34 | $-0.23 | -0.11% |
| Dec. 31, 2025 | $-0.27 | $-0.21 | -0.06% |
| Sept. 30, 2025 | $-0.31 | $-1.01 | 0.70% |
| June 30, 2025 | $-0.23 | $-0.92 | 0.69% |
| March 31, 2025 | $-0.19 | $-1.92 | 1.7% |
| June 30, 2023 | $-3.90 | $-7.07 | 3.2% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| CNTB | $159M | -2.8 | -99.8% | -86687.5% | -97.9% | — |
| CRBU | $151M | -1.0 | 11.7% | -1327.4% | -102.8% | — |
| OKUR | — | -0.7 | — | -1733.7% | -88.6% | — |
| CNTN | $112M | -2.7 | — | — | -18.0% | — |
| TNYA | $154M | -1.2 | — | — | -81.2% | — |
| UNCY | $128M | -3.5 | -29.0% | — | -113.9% | — |
| SPRB | $120M | -1.7 | -51.3% | — | -139.9% | — |
| EQ | $95M | -4.0 | 13.9% | — | -133.1% | — |
| IMDX | $215M | -4.5 | 115.6% | -1238.5% | 330.8% | 56.7% |
| HURA | — | -1.2 | — | — | — | — |
| INO | $120M | -1.0 | -70.0% | -130000.0% | -322.8% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $64.0K | $26M | $0 | |
| R&D Expense | $38M | $29M | $53M | |
| SG&A Expense | $20M | $19M | $16M | |
| Operating Expenses | $58M | $48M | $69M | |
| Operating Income | $-58M | $-22M | $-69M | |
| Other Non-op | $523.0K | $3M | $2M | |
| Pretax Income | $-55M | $-15M | $-62M | |
| Income Tax | $197.0K | $223.0K | $120.0K | |
| Net Income | $-55M | $-16M | $-62M | |
| EPS (Basic) | $-1.00 | $-0.28 | $-1.13 | |
| EPS (Diluted) | $-1.00 | $-0.28 | $-1.13 | |
| Shares (Basic) | 55,660,000 | 55,213,000 | 55,067,000 | |
| Shares (Diluted) | 55,660,000 | 55,213,000 | 55,067,000 | |
| EBITDA | $-57M | $-22M | · |
Balance Sheet 26
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $38M | $78M | $106M | |
| Short-term Investments | $6M | $15M | $13M | |
| Receivables | $13.0K | $789.0K | $0 | |
| Prepaid Expense | $7M | $2M | $4M | |
| Other Current Assets | · | $53.0K | $54.0K | |
| Current Assets | $51M | $97M | $123M | |
| PP&E (Net) | $4M | $4M | $4M | |
| PP&E (Gross) | $7M | $7M | $6M | |
| Accum. Depreciation | $3M | $3M | $2M | |
| Intangibles | $45.0K | $53.0K | $62.0K | |
| Other Non-current Assets | $646.0K | $33.0K | $24.0K | |
| Total Assets | $56M | $101M | $127M | |
| Accounts Payable | $2M | $342.0K | $2M | |
| Accrued Liabilities | $11M | $8M | $9M | |
| Current Liabilities | $14M | $8M | $25M | |
| Capital Leases | $368.0K | $24.0K | $180.0K | |
| Other Non-current Liabilities | $114.0K | $632.0K | · | |
| Total Liabilities | $14M | $9M | $26M | |
| Common Stock | $10.0K | $10.0K | $10.0K | |
| Paid-in Capital | $444M | $439M | $432M | |
| Retained Earnings | $-401M | $-345M | $-330M | |
| Treasury Stock | $180.0K | $180.0K | $180.0K | |
| AOCI | $-1M | $-2M | $-1M | |
| Stockholders' Equity | $42M | $92M | $101M | |
| Liabilities + Equity | $56M | $101M | $127M | |
| Shares Outstanding | 56,442,308 | 55,349,000 | 55,103,000 |
Cash Flow 11
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| D&A | $704.0K | $660.0K | $720.0K | |
| Stock-based Comp | $4M | $7M | $5M | |
| Restructuring | · | $3M | · | |
| Other Non-cash | $-156.0K | $-15M | · | |
| Operating Cash Flow | $-51M | $-24M | $-48M | |
| CapEx | $434.0K | $750.0K | $81.0K | |
| Investing Cash Flow | $10M | $-3M | $75M | |
| Financing Cash Flow | $1M | $227.0K | $45.0K | |
| Net Change in Cash | $-40M | $-27M | $27M | |
| Taxes Paid | · | $111.0K | $120.0K | |
| Free Cash Flow | $-52M | $-24M | · |
Profitability 7
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -90740.6% | -86.2% | · | |
| Net Margin | -86687.5% | -60.0% | · | |
| Pretax Margin | -86379.7% | -59.2% | · | |
| EBITDA Margin | -89640.6% | -83.7% | · | |
| ROA | -70.5% | -13.7% | · | |
| ROE | -97.9% | -16.2% | · | |
| ROIC | -138.8% | -24.7% | · |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 3.7 | 11.5 | · | |
| Quick Ratio | 3.3 | 11.2 | · |
Efficiency 2
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.2 | · | |
| Receivables Turnover | 0.2 | 66.0 | · |
Growth Rates 1
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | -99.8% | · | · |
Valuation (TTM) 10
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $64.0K | $26M | · | |
| Net Income TTM | $-55M | $-16M | · | |
| Market Cap | $159M | $76M | · | |
| P/E | -2.8 | -4.9 | · | |
| P/S | 2487.0 | 2.9 | · | |
| P/B | 3.8 | 0.8 | · | |
| P / Tangible Book | 3.8 | 0.8 | · | |
| P / Cash Flow | -3.1 | -3.2 | · | |
| P / FCF | -3.1 | -3.1 | · | |
| Earnings Yield | -35.5% | -20.3% | · |
Income Statement 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $3M | $169.0K | $0 | $16.0K | $48.0K | $0 | $698.0K | $1M | $24M | |
| R&D Expense | $16M | $15M | $11M | $11M | $9M | $7M | $6M | $9M | $5M | |
| SG&A Expense | $4M | $5M | $4M | $7M | $5M | $5M | $4M | $6M | $5M | |
| Operating Expenses | $20M | $20M | $16M | $18M | $13M | $11M | $10M | $15M | $10M | |
| Operating Income | $-18M | $-20M | $-16M | $-18M | $-13M | $-11M | $-10M | $-14M | $14M | |
| Other Non-op | $67.0K | $-3.0K | $60.0K | $-7.0K | $-39.0K | $509.0K | $-30.0K | $-108.0K | $9.0K | |
| Pretax Income | $-17M | $-19M | $-15M | $-17M | $-13M | $-10M | $-9M | $-13M | $15M | |
| Income Tax | $60.0K | $48.0K | $27.0K | $61.0K | $55.0K | $54.0K | $106.0K | $57.0K | $30.0K | |
| Net Income | $-17M | $-19M | $-15M | $-17M | $-13M | $-10M | $-9M | $-13M | $15M | |
| EPS (Basic) | $-0.27 | $-0.34 | $-0.27 | $-0.31 | $-0.23 | $-0.19 | $-0.16 | $-0.23 | $0.27 | |
| EPS (Diluted) | $-0.27 | $-0.34 | $-0.27 | $-0.31 | $-0.23 | $-0.19 | $-0.16 | $-0.23 | $0.27 | |
| Shares (Basic) | 62,884,000 | 56,545,000 | -110,906,000 | 55,716,000 | 55,498,000 | 55,352,000 | -110,330,000 | 55,254,000 | 55,186,000 | |
| Shares (Diluted) | 62,884,000 | 56,545,000 | -110,906,000 | 55,716,000 | 55,498,000 | 55,352,000 | -110,854,000 | 55,254,000 | 55,710,000 | |
| EBITDA | $-18M | $-19M | · | $-18M | $-13M | $-11M | · | · | · |
Balance Sheet 26
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $27M | $46M | $38M | $38M | $41M | $48M | $78M | · | · | |
| Short-term Investments | $4M | $0 | $6M | $17M | $31M | $36M | $15M | · | · | |
| Receivables | $3M | $0 | $13.0K | $17.0K | $0 | $8.0K | $789.0K | · | · | |
| Prepaid Expense | $4M | $9M | $7M | $8M | $6M | $4M | $2M | · | · | |
| Other Current Assets | · | · | · | · | $228.0K | $65.0K | · | · | · | |
| Current Assets | $39M | $55M | $51M | $63M | $78M | $88M | $97M | · | · | |
| PP&E (Net) | $4M | $4M | $4M | $4M | $4M | $4M | $4M | · | · | |
| PP&E (Gross) | · | · | $7M | · | · | · | $7M | · | · | |
| Accum. Depreciation | · | · | $3M | · | · | · | $3M | · | · | |
| Intangibles | $42.0K | $43.0K | $45.0K | $47.0K | $48.0K | $50.0K | $53.0K | · | · | |
| Other Non-current Assets | $646.0K | $646.0K | $646.0K | $45.0K | $45.0K | $45.0K | $33.0K | · | · | |
| Total Assets | $43M | $60M | $56M | $67M | $83M | $93M | $101M | · | · | |
| Accounts Payable | $2M | $4M | $2M | $2M | $2M | $817.0K | $342.0K | · | · | |
| Accrued Liabilities | $14M | $12M | $11M | $9M | $8M | $7M | $8M | · | · | |
| Current Liabilities | $16M | $17M | $14M | $11M | $11M | $9M | $8M | · | · | |
| Capital Leases | $203.0K | $287.0K | $368.0K | $445.0K | $520.0K | $594.0K | $24.0K | · | · | |
| Other Non-current Liabilities | $107.0K | $111.0K | $114.0K | $118.0K | $122.0K | $627.0K | $632.0K | · | · | |
| Total Liabilities | $17M | $17M | $14M | $12M | $11M | $10M | $9M | · | · | |
| Common Stock | $11.0K | $11.0K | $10.0K | $10.0K | $10.0K | $10.0K | $10.0K | · | · | |
| Paid-in Capital | $466M | $464M | $444M | $443M | $441M | $440M | $439M | · | · | |
| Retained Earnings | $-438M | $-420M | $-401M | $-386M | $-369M | $-356M | $-345M | · | · | |
| Treasury Stock | $180.0K | $180.0K | $180.0K | $180.0K | $180.0K | $180.0K | $180.0K | · | · | |
| AOCI | $-962.0K | $-1M | $-1M | $-1M | $-1M | $-2M | $-2M | · | · | |
| Stockholders' Equity | $27M | $43M | $42M | $55M | $71M | $83M | $92M | · | · | |
| Liabilities + Equity | $43M | $60M | $56M | $67M | $83M | $93M | $101M | · | · | |
| Shares Outstanding | 62,974,309 | 62,711,690 | 56,442,308 | 55,786,000 | 55,580,000 | 55,352,000 | 55,349,208 | · | · |
Cash Flow 13
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $161.0K | $164.0K | $181.0K | $179.0K | $171.0K | $173.0K | $158.0K | $176.0K | $162.0K | |
| Stock-based Comp | $1M | $1M | $917.0K | $916.0K | $951.0K | $942.0K | $1M | $2M | $2M | |
| Restructuring | · | · | · | · | · | · | $0 | $2M | $1M | |
| Other Non-cash | · | $2M | · | · | · | $-802.0K | · | · | · | |
| Operating Cash Flow | $-16M | $-16M | $-11M | $-17M | $-13M | $-10M | $-2M | $-13M | $-8M | |
| CapEx | $0 | $0 | $16.0K | $34.0K | $303.0K | $81.0K | $313.0K | $147.0K | $290.0K | |
| Investing Cash Flow | $-4M | $6M | $11M | $14M | $5M | $-21M | $-16M | $-147.0K | $3M | |
| Stock Issued | $0 | $137.0K | · | · | $18.0K | $2.0K | · | · | · | |
| Net Stock Activity | · | $137.0K | · | · | · | · | · | · | · | |
| Financing Cash Flow | $1M | $18M | $715.0K | $215.0K | $161.0K | $2.0K | $106.0K | $0 | $121.0K | |
| Net Change in Cash | $-19M | $8M | $500.0K | $-3M | $-7M | $-31M | $-19M | $-13M | $-4M | |
| Taxes Paid | · | · | · | $0 | · | · | · | $111.0K | · | |
| Free Cash Flow | · | $-16M | · | · | · | $-10M | · | · | · |
Profitability 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -636.0% | -11601.8% | · | -110481.2% | -27966.7% | · | · | · | · | |
| Net Margin | -624.4% | -11478.1% | · | -107500.0% | -26872.9% | · | · | · | · | |
| Pretax Margin | -622.2% | -11449.7% | · | -107118.8% | -26758.3% | · | · | · | · | |
| EBITDA Margin | -636.0% | -11504.7% | · | -110481.2% | -27966.7% | · | · | · | · | |
| ROA | -27.4% | -25.4% | · | -51.1% | -31.2% | -22.2% | · | · | · | |
| ROE | -35.2% | -30.9% | · | -62.1% | -36.2% | -24.8% | · | · | · | |
| ROIC | -65.8% | -46.1% | · | -32.0% | -18.9% | -13.9% | · | · | · |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.4 | 3.2 | · | 5.5 | 7.2 | 10.2 | · | · | · | |
| Quick Ratio | 2.1 | 2.7 | · | 4.8 | 6.7 | 9.8 | · | · | · |
Efficiency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | · | · | · | · | |
| Receivables Turnover | 1.9 | 42.2 | · | 1.9 | · | · | · | · | · |
Valuation (TTM) 10
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $3M | $233.0K | · | · | · | · | · | · | · | |
| Net Income TTM | $-67M | $-60M | · | $-53M | $-21M | $-17M | · | · | · | |
| Market Cap | $150M | $164M | · | $84M | $54M | $30M | · | · | · | |
| P/E | -2.1 | -2.4 | · | -1.6 | -2.6 | -1.8 | · | · | · | |
| P/S | 49.9 | 705.2 | · | · | · | · | · | · | · | |
| P/B | 5.6 | 3.9 | · | 1.5 | 0.8 | 0.4 | · | · | · | |
| P / Tangible Book | 5.6 | 3.9 | · | 1.5 | 0.8 | 0.4 | · | · | · | |
| P / Cash Flow | · | -10.3 | · | · | · | -3.1 | · | · | · | |
| P / FCF | · | -10.3 | · | · | · | -3.0 | · | · | · | |
| Earnings Yield | -48.3% | -40.8% | · | -63.6% | -38.8% | -56.4% | · | · | · |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Revenue | $64.0K | $26M | $0 |
| Operating Margin % | -90740.6% | -86.2% | — |
| Net Income | $-55M | $-16M | $-62M |
| Diluted EPS | $-1.00 | $-0.28 | $-1.13 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Current Ratio | 3.7 | 11.5 | — |
| Quick Ratio | 3.3 | 11.2 | — |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | |
|---|---|---|---|
| Free Cash Flow | $-52M | $-24M | — |
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Institutional owners (13F) 56 filers · $29.2M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 24 (+4 vs prior Q) | 9 (+6 vs prior Q) | 14 (+7 vs prior Q) | 11 (+4 vs prior Q) | -260K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Ikarian Capital, LLC | $10,801,710 | 4,538,534 | 36.96% | Shares |
| 683 Capital Management, LLC | $3,058,300 | 1,285,000 | 10.46% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $2,317,482 | 973,732 | 7.93% | Shares |
| PERCEPTIVE ADVISORS LLC | $1,886,616 | 792,696 | 6.45% | Shares |
| ADAR1 Capital Management, LLC | $1,666,000 | 700,000 | 5.70% | Shares |
| BML Capital Management, LLC | $1,364,423 | 573,287 | 4.67% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1,297,100 | 545,000 | 4.44% | Shares |
| Knott David M Jr | $1,058,772 | 444,862 | 3.62% | Shares |
| Stonepine Capital Management, LLC | $866,925 | 364,254 | 2.97% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $561,099 | 235,756 | 1.92% | Shares |
| TWO SIGMA INVESTMENTS, LP | $474,527 | 199,381 | 1.62% | Shares |
| DIADEMA PARTNERS LP | $468,824 | 196,985 | 1.60% | Shares |
| MARSHALL WACE, LLP | $388,341 | 163,168 | 1.33% | Shares |
| Burkehill Global Management, LP | $357,000 | 150,000 | 1.22% | Shares |
| Richmond Brothers, Inc. | $334,169 | 140,408 | 1.14% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $244,557 | 102,755 | 0.84% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $243,112 | 102,148 | 0.83% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $207,774 | 87,300 | 0.71% | Shares |
| SIMPLEX TRADING, LLC | $195,036 | 81,948 | 0.67% | Shares |
| STATE STREET CORP | $158,746 | 66,700 | 0.54% | Shares |
| UBS Group AG | $158,153 | 66,451 | 0.54% | Shares |
| Persistent Asset Partners Ltd | $118,698 | 49,873 | 0.41% | Shares |
| Koa Wealth Management, LLC | $118,048 | 49,600 | 0.40% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $115,192 | 48,400 | 0.39% | Shares |
| MILLENNIUM MANAGEMENT LLC | $104,025 | 43,708 | 0.36% | Shares |
| BANK OF AMERICA CORP /DE/ | $97,390 | 40,920 | 0.33% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $87,489 | 36,760 | 0.30% | Shares |
| XTX Topco Ltd | $68,208 | 28,659 | 0.23% | Shares |
| Bank of New York Mellon Corp | $57,006 | 23,952 | 0.20% | Shares |
| Nuveen, LLC | $47,060 | 19,773 | 0.16% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $43,554 | 18,300 | 0.15% | Put option |
| Y-Intercept (Hong Kong) Ltd | $35,864 | 15,069 | 0.12% | Shares |
| WELLS FARGO & COMPANY/MN | $31,511 | 13,240 | 0.11% | Shares |
| SmartHarvest Portfolios, LLC | $30,695 | 12,897 | 0.11% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $26,927 | 11,314 | 0.09% | Shares |
| MONOGRAPH WEALTH ADVISORS, LLC | $26,489 | 11,130 | 0.09% | Shares |
| RHUMBLINE ADVISERS | $26,124 | 10,979 | 0.09% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $16,432 | 6,904 | 0.06% | Shares |
| JPMORGAN CHASE & CO | $14,794 | 6,216 | 0.05% | Shares |
| CITIGROUP INC | $14,568 | 6,121 | 0.05% | Shares |
| Legal & General Group Plc | $5,748 | 2,415 | 0.02% | Shares |
| NORTHERN TRUST CORP | $5,693 | 2,392 | 0.02% | Shares |
| MORGAN STANLEY | $5,622 | 2,362 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $5,450 | 2,290 | 0.02% | Shares |
| BARCLAYS PLC | $4,698 | 1,974 | 0.02% | Shares |
| Russell Investments Group, Ltd. | $2,844 | 1,195 | 0.01% | Shares |
| BlackRock, Inc. | $2,509 | 1,054 | 0.01% | Shares |
| HUNTINGTON NATIONAL BANK | $2,370 | 996 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $2,099 | 882 | 0.01% | Shares |
| ROYAL BANK OF CANADA | $1,000 | 540 | 0.00% | Shares |
| FMR LLC | $747 | 314 | 0.00% | Shares |
| Sterling Capital Management LLC | $357 | 150 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $157 | 66 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $30 | 12,469 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $14 | 6 | 0.00% | Shares |
| FNY Investment Advisers, LLC | $11 | 5,000 | 0.00% | Shares |
Company insiders 3 insiders · 0 officers · 3 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Kleanthis Gabriel Xanthopoulos | Director | June 30, 2026 A | 86,554 | 0 | 0 | $0 |
| Jean I Liu | Director | June 30, 2026 A | 11,779 | 0 | 0 | $0 |
| James Huang | Director | May 29, 2026 P | 13,310,000 | 2 | 0 | $4,374,000 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 2 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Panacea Innovation Limited, Panacea Venture Healthcare Fund II, L.P., Panacea Venture Healthcare Fund II GP Company, Ltd., James Huang ×6 filings | April 1, 2026 | 21.20% | Amendment | — | SEC |
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×6 filings | Feb. 27, 2024 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
ETF ownership Held by 6 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| IWO · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IWM · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IWC · iShares Trust | — | — | Aug. 18, 2026 | Daily |