CNTB Connect Biopharma Holdings Limited - Ordinary Shares
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 12, 2026
$0.93
· of 52w range
· above low
· to high
$0.8952w low
$3.8252w high
Market Cap (MRQ)
$58M
P/E (TTM)
-0.8
EPS (TTM)
$-1.19
Revenue (TTM)
$3M
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52W Range
$1–$4
Analyst Rating
BUY
Price Target
$6
P/E
-0.8
ROE
-140.5%
Net Profit Margin
-2336.3%
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CNTB Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$0.93
Market Cap (MRQ)
$58M
P/E (TTM)
-0.8
EPS (TTM)
$-1.19
Revenue (TTM)
$3M
ROE (TTM)
-140.5%
52W Range
$1–$4
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue$64.0K2023-12-31 → 2025-12-31
EPS$-1.002023-12-31 → 2025-12-31
Free Cash Flow$-52M2024-12-31 → 2025-12-31
Net margin-2336.3%2024-12-31 → 2025-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | CNTB | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E (TTM) | -0.8 | · | · | · | |
| P/S (TTM) | 19.8 | · | 28.7 | Pricier | |
| P/B (MRQ) | 2.2 | · | 1.7 | Overvalued | |
| Price / FCF (TTM) | -1.0 | · | · | · | |
| Price / Cash Flow (TTM) | -1.0 | · | · | · | |
| Price / Tangible Book (MRQ) | 2.2 | · | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | CNTB | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Operating Margin (TTM) | -2384.5% | · | -682.2% | In line | |
| EBITDA Margin (TTM) | -2361.3% | · | -682.2% | In line | |
| Pretax Margin (TTM) | -2329.7% | · | -487.0% | Weak | |
| Net Profit Margin (TTM) | -2336.3% | · | -781.7% | Top tier | |
| ROA (TTM) | -109.3% | · | -62.3% | Weak | |
| ROE (TTM) | -140.5% | · | -66.9% | Weak | |
| ROIC | -138.8% | · | -58.6% | Weak |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | CNTB | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 2.4 | · | 5.5 | Low liquidity | |
| Quick Ratio (MRQ) | 2.1 | · | 5.1 | Low liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
| Metric | 5Y trend | CNTB | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Revenue YoY | -99.8% | · | · | · |
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
| Metric | 5Y trend | CNTB | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | 0.0 | In line | |
| Receivables Turnover | 0.2 | · | · | · | |
| Revenue / Employee | ≈$1.0K | · | · | · |
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
30.8%
Next Report
Nov 10, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 17, 2026 | $-0.27 | $-0.32 | 16.0% |
| March 31, 2026 | May 22, 2026 | $-0.34 | $-0.23 | -50.2% |
| Dec. 31, 2025 | $-0.27 | $-0.21 | -29.8% | |
| Sept. 30, 2025 | $-0.31 | $-1.01 | 69.4% | |
| June 30, 2025 | $-0.23 | $-0.92 | 75.0% | |
| March 31, 2025 | $-0.19 | $-1.92 | 90.1% | |
| June 30, 2023 | $-3.90 | $-7.07 | 44.8% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $64.0K | $26M | $0 | |
| R&D Expense | $38M | $29M | $53M | |
| SG&A Expense | $20M | $19M | $16M | |
| Operating Expenses | $58M | $48M | $69M | |
| Operating Income | $-58M | $-22M | $-69M | |
| Other Non-op | $523.0K | $3M | $2M | |
| Pretax Income | $-55M | $-15M | $-62M | |
| Income Tax | $197.0K | $223.0K | $120.0K | |
| Net Income | $-55M | $-16M | $-62M | |
| EPS (Basic) | $-1.00 | $-0.28 | $-1.13 | |
| EPS (Diluted) | $-1.00 | $-0.28 | $-1.13 | |
| Shares (Basic) | 55,660,000 | 55,213,000 | 55,067,000 | |
| Shares (Diluted) | 55,660,000 | 55,213,000 | 55,067,000 | |
| EBITDA | $-57M | $-22M | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $38M | $78M | $106M | |
| Short-term Investments | $6M | $15M | $13M | |
| Receivables | $13.0K | $789.0K | $0 | |
| Prepaid Expense | $7M | $2M | $4M | |
| Other Current Assets | · | $53.0K | $54.0K | |
| Current Assets | $51M | $97M | $123M | |
| PP&E (Net) | $4M | $4M | $4M | |
| PP&E (Gross) | $7M | $7M | $6M | |
| Accum. Depreciation | $3M | $3M | $2M | |
| Intangibles | $45.0K | $53.0K | $62.0K | |
| Other Non-current Assets | $646.0K | $33.0K | $24.0K | |
| Total Assets | $56M | $101M | $127M | |
| Accounts Payable | $2M | $342.0K | $2M | |
| Accrued Liabilities | $11M | $8M | $9M | |
| Current Liabilities | $14M | $8M | $25M | |
| Capital Leases | $368.0K | $24.0K | $180.0K | |
| Other Non-current Liabilities | $114.0K | $632.0K | · | |
| Total Liabilities | $14M | $9M | $26M | |
| Common Stock | $10.0K | $10.0K | $10.0K | |
| Paid-in Capital | $444M | $439M | $432M | |
| Retained Earnings | $-401M | $-345M | $-330M | |
| Treasury Stock | $180.0K | $180.0K | $180.0K | |
| AOCI | $-1M | $-2M | $-1M | |
| Stockholders' Equity | $42M | $92M | $101M | |
| Liabilities + Equity | $56M | $101M | $127M | |
| Shares Outstanding | 56,442,308 | 55,349,000 | 55,103,000 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| D&A | $704.0K | $660.0K | $720.0K | |
| Stock-based Comp | $4M | $7M | $5M | |
| Restructuring | · | $3M | · | |
| Other Non-cash | $-156.0K | $-15M | · | |
| Operating Cash Flow | $-51M | $-24M | $-48M | |
| CapEx | $434.0K | $750.0K | $81.0K | |
| Investing Cash Flow | $10M | $-3M | $75M | |
| Financing Cash Flow | $1M | $227.0K | $45.0K | |
| Net Change in Cash | $-40M | $-27M | $27M | |
| Taxes Paid | · | $111.0K | $120.0K | |
| Free Cash Flow | $-52M | $-24M | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -90740.6% | -86.2% | · | |
| Net Margin | -86687.5% | -60.0% | · | |
| Pretax Margin | -86379.7% | -59.2% | · | |
| EBITDA Margin | -89640.6% | -83.7% | · | |
| ROA | -70.5% | -13.7% | · | |
| ROE | -97.9% | -16.2% | · | |
| ROIC | -138.8% | -24.7% | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 3.7 | 11.5 | · | |
| Quick Ratio | 3.3 | 11.2 | · |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.2 | · | |
| Receivables Turnover | 0.2 | 66.0 | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Book Value / Share | $0.74 | $1.67 | · | |
| Revenue / Share | $0.00 | $0.47 | · | |
| Cash Flow / Share | $-0.92 | $-0.43 | · | |
| Cash / Share | $0.68 | $1.41 | · | |
| EPS (TTM) | $-1.00 | $-0.28 | · |
Growth Rates
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | -99.8% | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $64.0K | $26M | · | |
| Net Income TTM | $-55M | $-16M | · | |
| Market Cap | $159M | $76M | · | |
| P/E | -2.8 | -4.9 | · | |
| P/S | 2487.0 | 2.9 | · | |
| P/B | 3.8 | 0.8 | · | |
| P / Tangible Book | 3.8 | 0.8 | · | |
| P / Cash Flow | -3.1 | -3.2 | · | |
| P / FCF | -3.1 | -3.1 | · | |
| Earnings Yield | -35.5% | -20.3% | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $3M | $169.0K | $0 | $16.0K | $48.0K | $0 | $698.0K | $1M | $24M | |
| R&D Expense | $16M | $15M | $11M | $11M | $9M | $7M | $6M | $9M | $5M | |
| SG&A Expense | $4M | $5M | $4M | $7M | $5M | $5M | $4M | $6M | $5M | |
| Operating Expenses | $20M | $20M | $16M | $18M | $13M | $11M | $10M | $15M | $10M | |
| Operating Income | $-18M | $-20M | $-16M | $-18M | $-13M | $-11M | $-10M | $-14M | $14M | |
| Other Non-op | $67.0K | $-3.0K | $60.0K | $-7.0K | $-39.0K | $509.0K | $-30.0K | $-108.0K | $9.0K | |
| Pretax Income | $-17M | $-19M | $-15M | $-17M | $-13M | $-10M | $-9M | $-13M | $15M | |
| Income Tax | $60.0K | $48.0K | $27.0K | $61.0K | $55.0K | $54.0K | $106.0K | $57.0K | $30.0K | |
| Net Income | $-17M | $-19M | $-15M | $-17M | $-13M | $-10M | $-9M | $-13M | $15M | |
| EPS (Basic) | $-0.27 | $-0.34 | $-0.27 | $-0.31 | $-0.23 | $-0.19 | $-0.16 | $-0.23 | $0.27 | |
| EPS (Diluted) | $-0.27 | $-0.34 | $-0.27 | $-0.31 | $-0.23 | $-0.19 | $-0.16 | $-0.23 | $0.27 | |
| Shares (Basic) | 62,884,000 | 56,545,000 | · | 55,716,000 | 55,498,000 | 55,352,000 | · | 55,254,000 | 55,186,000 | |
| Shares (Diluted) | 62,884,000 | 56,545,000 | · | 55,716,000 | 55,498,000 | 55,352,000 | · | 55,254,000 | 55,710,000 | |
| EBITDA | $-18M | $-19M | · | $-18M | $-13M | $-11M | · | · | · |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $27M | $46M | $38M | $38M | $41M | $48M | $78M | · | · | |
| Short-term Investments | $4M | $0 | $6M | $17M | $31M | $36M | $15M | · | · | |
| Receivables | $3M | $0 | $13.0K | $17.0K | $0 | $8.0K | $789.0K | · | · | |
| Prepaid Expense | $4M | $9M | $7M | $8M | $6M | $4M | $2M | · | · | |
| Other Current Assets | · | · | · | · | $228.0K | $65.0K | · | · | · | |
| Current Assets | $39M | $55M | $51M | $63M | $78M | $88M | $97M | · | · | |
| PP&E (Net) | $4M | $4M | $4M | $4M | $4M | $4M | $4M | · | · | |
| PP&E (Gross) | · | · | $7M | · | · | · | $7M | · | · | |
| Accum. Depreciation | · | · | $3M | · | · | · | $3M | · | · | |
| Intangibles | $42.0K | $43.0K | $45.0K | $47.0K | $48.0K | $50.0K | $53.0K | · | · | |
| Other Non-current Assets | $646.0K | $646.0K | $646.0K | $45.0K | $45.0K | $45.0K | $33.0K | · | · | |
| Total Assets | $43M | $60M | $56M | $67M | $83M | $93M | $101M | · | · | |
| Accounts Payable | $2M | $4M | $2M | $2M | $2M | $817.0K | $342.0K | · | · | |
| Accrued Liabilities | $14M | $12M | $11M | $9M | $8M | $7M | $8M | · | · | |
| Current Liabilities | $16M | $17M | $14M | $11M | $11M | $9M | $8M | · | · | |
| Capital Leases | $203.0K | $287.0K | $368.0K | $445.0K | $520.0K | $594.0K | $24.0K | · | · | |
| Other Non-current Liabilities | $107.0K | $111.0K | $114.0K | $118.0K | $122.0K | $627.0K | $632.0K | · | · | |
| Total Liabilities | $17M | $17M | $14M | $12M | $11M | $10M | $9M | · | · | |
| Common Stock | $11.0K | $11.0K | $10.0K | $10.0K | $10.0K | $10.0K | $10.0K | · | · | |
| Paid-in Capital | $466M | $464M | $444M | $443M | $441M | $440M | $439M | · | · | |
| Retained Earnings | $-438M | $-420M | $-401M | $-386M | $-369M | $-356M | $-345M | · | · | |
| Treasury Stock | $180.0K | $180.0K | $180.0K | $180.0K | $180.0K | $180.0K | $180.0K | · | · | |
| AOCI | $-962.0K | $-1M | $-1M | $-1M | $-1M | $-2M | $-2M | · | · | |
| Stockholders' Equity | $27M | $43M | $42M | $55M | $71M | $83M | $92M | · | · | |
| Liabilities + Equity | $43M | $60M | $56M | $67M | $83M | $93M | $101M | · | · | |
| Shares Outstanding | 62,974,309 | 62,711,690 | 56,442,308 | 55,786,000 | 55,580,000 | 55,352,000 | 55,349,208 | · | · |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $161.0K | $164.0K | $181.0K | $179.0K | $171.0K | $173.0K | $158.0K | $176.0K | $162.0K | |
| Stock-based Comp | $1M | $1M | $917.0K | $916.0K | $951.0K | $942.0K | $1M | $2M | $2M | |
| Restructuring | · | · | · | · | · | · | $0 | $2M | $1M | |
| Other Non-cash | · | $2M | · | · | · | $-802.0K | · | · | · | |
| Operating Cash Flow | $-16M | $-16M | $-11M | $-17M | $-13M | $-10M | $-2M | $-13M | $-8M | |
| CapEx | $0 | $0 | $16.0K | $34.0K | $303.0K | $81.0K | $313.0K | $147.0K | $290.0K | |
| Investing Cash Flow | $-4M | $6M | $11M | $14M | $5M | $-21M | $-16M | $-147.0K | $3M | |
| Stock Issued | $0 | $137.0K | · | · | $18.0K | $2.0K | · | · | · | |
| Net Stock Activity | · | $137.0K | · | · | · | · | · | · | · | |
| Financing Cash Flow | $1M | $18M | $715.0K | $215.0K | $161.0K | $2.0K | $106.0K | $0 | $121.0K | |
| Net Change in Cash | $-19M | $8M | $500.0K | $-3M | $-7M | $-31M | $-19M | $-13M | $-4M | |
| Taxes Paid | · | · | · | $0 | · | · | · | $111.0K | · | |
| Free Cash Flow | · | $-16M | · | · | · | $-10M | · | · | · |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -636.0% | -11601.8% | · | -110481.2% | -27966.7% | · | · | · | · | |
| Net Margin | -624.4% | -11478.1% | · | -107500.0% | -26872.9% | · | · | · | · | |
| Pretax Margin | -622.2% | -11449.7% | · | -107118.8% | -26758.3% | · | · | · | · | |
| EBITDA Margin | -636.0% | -11504.7% | · | -110481.2% | -27966.7% | · | · | · | · | |
| ROA | -27.4% | -25.4% | · | -51.1% | -31.2% | -22.2% | · | · | · | |
| ROE | -35.2% | -30.9% | · | -62.1% | -36.2% | -24.8% | · | · | · | |
| ROIC | -65.8% | -46.1% | · | -32.0% | -18.9% | -13.9% | · | · | · |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.4 | 3.2 | · | 5.5 | 7.2 | 10.2 | · | · | · | |
| Quick Ratio | 2.1 | 2.7 | · | 4.8 | 6.7 | 9.8 | · | · | · |
Efficiency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | · | · | · | · | |
| Receivables Turnover | 1.9 | 42.2 | · | 1.9 | · | · | · | · | · |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $0.43 | $0.68 | · | $0.99 | $1.28 | $1.50 | · | · | · | |
| Revenue / Share | $0.04 | $0.00 | · | $0.00 | $0.00 | · | · | · | · | |
| Cash Flow / Share | · | $-0.28 | · | · | · | $-0.18 | · | · | · | |
| Cash / Share | $0.43 | $0.73 | · | $0.68 | $0.73 | $0.86 | · | · | · | |
| EPS (TTM) | $-1.19 | $-1.15 | · | $-0.89 | $-0.81 | $-0.31 | · | · | · |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 |
|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $3M | $233.0K | · | $762.0K | $2M | $26M | · | · | · | |
| Net Income TTM | $-69M | $-65M | · | $-49M | $-45M | $-17M | · | · | · | |
| Market Cap | $150M | $164M | · | $84M | $54M | $30M | · | · | · | |
| P/E | -2.0 | -2.3 | · | -1.7 | -1.2 | -1.8 | · | · | · | |
| P/S | 50.8 | 705.2 | · | 110.5 | 27.7 | 1.2 | · | · | · | |
| P/B | 5.6 | 3.9 | · | 1.5 | 0.8 | 0.4 | · | · | · | |
| P / Tangible Book | 5.6 | 3.9 | · | 1.5 | 0.8 | 0.4 | · | · | · | |
| P / Cash Flow | · | -10.3 | · | · | · | -3.1 | · | · | · | |
| Earnings Yield | -50.0% | -43.9% | · | -58.9% | -82.7% | -56.4% | · | · | · |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Revenue | $64.0K | $26M | $0 |
| Operating Margin % | -90740.6% | -86.2% | · |
| Net Income | $-55M | $-16M | $-62M |
| Diluted EPS | $-1.00 | $-0.28 | $-1.13 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Current Ratio | 3.7 | 11.5 | · |
| Quick Ratio | 3.3 | 11.2 | · |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 |
|---|---|---|---|
| Free Cash Flow | $-52M | $-24M | · |
Institutional owners (13F) 56 filers · $33.0M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
56
Value held
$33.0M
New positions
24
Exited positions
9
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 24 (+4 vs prior Q) | 9 (+6 vs prior Q) | 15 (+7 vs prior Q) | 10 (+4 vs prior Q) | +870K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Ikarian Capital, LLC | $10,801,710 | 4,538,534 | 32.71% | Shares |
| 683 Capital Management, LLC | $3,058,300 | 1,285,000 | 9.26% | Shares |
| BOOTHBAY FUND MANAGEMENT, LLC | $2,317,482 | 973,732 | 7.02% | Shares |
| BlackRock, Inc. | $2,074,534 | 871,653 | 6.28% | Shares |
| PERCEPTIVE ADVISORS LLC | $1,886,616 | 792,696 | 5.71% | Shares |
| ADAR1 Capital Management, LLC | $1,666,000 | 700,000 | 5.05% | Shares |
| BML Capital Management, LLC | $1,364,423 | 573,287 | 4.13% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1,297,100 | 545,000 | 3.93% | Shares |
| Richmond Brothers, Inc. | $1,274,755 | 535,612 | 3.86% | Shares |
| Knott David M Jr | $1,058,772 | 444,862 | 3.21% | Shares |
| Stonepine Capital Management, LLC | $866,925 | 364,254 | 2.63% | Shares |
| MARSHALL WACE, LLP | $798,830 | 335,642 | 2.42% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $612,740 | 257,454 | 1.86% | Shares |
| TWO SIGMA INVESTMENTS, LP | $474,527 | 199,381 | 1.44% | Shares |
| DIADEMA PARTNERS LP | $468,824 | 196,985 | 1.42% | Shares |
| Burkehill Global Management, LP | $357,000 | 150,000 | 1.08% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $244,557 | 102,755 | 0.74% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $243,112 | 102,148 | 0.74% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $207,774 | 87,300 | 0.63% | Shares |
| NORTHERN TRUST CORP | $197,212 | 82,862 | 0.60% | Shares |
| SIMPLEX TRADING, LLC | $195,036 | 81,948 | 0.59% | Shares |
| STATE STREET CORP | $158,746 | 66,700 | 0.48% | Shares |
| UBS Group AG | $158,153 | 66,451 | 0.48% | Shares |
| Persistent Asset Partners Ltd | $118,698 | 49,873 | 0.36% | Shares |
| Koa Wealth Management, LLC | $118,048 | 49,600 | 0.36% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $115,192 | 48,400 | 0.35% | Shares |
| MILLENNIUM MANAGEMENT LLC | $104,025 | 43,708 | 0.32% | Shares |
| BANK OF AMERICA CORP /DE/ | $97,390 | 40,920 | 0.29% | Shares |
| ROYAL BANK OF CANADA | $97,000 | 40,940 | 0.29% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $87,489 | 36,760 | 0.26% | Shares |
| XTX Topco Ltd | $68,208 | 28,659 | 0.21% | Shares |
| Bank of New York Mellon Corp | $57,008 | 23,953 | 0.17% | Shares |
| Nuveen, LLC | $47,060 | 19,773 | 0.14% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $43,554 | 18,300 | 0.13% | Put option |
| Y-Intercept (Hong Kong) Ltd | $35,864 | 15,069 | 0.11% | Shares |
| WELLS FARGO & COMPANY/MN | $31,511 | 13,240 | 0.10% | Shares |
| SmartHarvest Portfolios, LLC | $30,695 | 12,897 | 0.09% | Shares |
| JPMORGAN CHASE & CO | $27,889 | 11,718 | 0.08% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $26,927 | 11,314 | 0.08% | Shares |
| MONOGRAPH WEALTH ADVISORS, LLC | $26,489 | 11,130 | 0.08% | Shares |
| RHUMBLINE ADVISERS | $26,124 | 10,979 | 0.08% | Shares |
| MORGAN STANLEY | $20,561 | 8,639 | 0.06% | Shares |
| CITIGROUP INC | $16,627 | 6,986 | 0.05% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $16,432 | 6,904 | 0.05% | Shares |
| BARCLAYS PLC | $6,852 | 2,879 | 0.02% | Shares |
| Legal & General Group Plc | $5,748 | 2,415 | 0.02% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $5,450 | 2,290 | 0.02% | Shares |
| Russell Investments Group, Ltd. | $2,844 | 1,195 | 0.01% | Shares |
| HUNTINGTON NATIONAL BANK | $2,370 | 996 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $2,099 | 882 | 0.01% | Shares |
Activists & 5%+ owners 2 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Panacea Innovation Limited, Panacea Venture Healthcare Fund II, L.P., Panacea Venture Healthcare Fund II GP Company, Ltd., James Huang ×6 filings | April 1, 2026 | 21.20% | Amendment | · | SEC |
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×6 filings | Feb. 27, 2024 | · | Initial filing | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 3 insiders · 0 officers · 3 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Kleanthis Gabriel Xanthopoulos | Director | Sept. 30, 2026 A | 91,554 | 0 | 0 | $0 |
| Jean I Liu | Director | Sept. 30, 2026 A | 20,763 | 0 | 0 | $0 |
| James Huang | Director | May 29, 2026 P | 13,310,000 | 2 | 0 | $4,374,000 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 7 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| IWC · iShares Trust | 0.01% | 49,778 SH | Sept. 11, 2026 | Daily |
| IWO · iShares Trust | 0.01% | 379,621 SH | Sept. 11, 2026 | Daily |
| IWM · iShares Trust | 0.00% | 377,004 SH | Sept. 11, 2026 | Daily |
| RSSL · Global X Funds | 0.00% | 7,144 NS | July 31, 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0.00% | 86,692 SH | Aug. 19, 2026 | Daily |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0.00% | 6,283 SH | Aug. 19, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0.00% | 9,780 SH | Aug. 19, 2026 | Daily |
CNTB Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 14 analysts
BUY
Median target
$6.50
+601.2%
5 35.7%
Strong Buy
8 57.1%
Buy
1 7.1%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
8 analysts · 2026-09-28Mean target $6.50 +601.2%
← Below all targets
Current price $0.93
Low$4.00
Mean$6.50
High$10.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| CNTB | $159M | -2.8 | -99.8% | -86687.5% | -97.9% | · |
| GOSS | $724M | -4.1 | -57.7% | -351.5% | 201.8% | · |
| NMAD | · | · | · | · | · | · |
| FRMM | · | · | · | -6881.3% | -368.1% | · |
| INKT | · | -3.8 | 4.5% | -6931.8% | 63.4% | · |
| ACET | · | -0.5 | · | · | · | · |
| BOLD | $27M | -0.5 | · | · | -46.7% | · |
| CLNN | $64M | · | -41.5% | -13086.5% | 200.2% | · |
| KLRS | $193M | -3.0 | · | · | -65.8% | · |
| INMB | $41M | -0.8 | 257.1% | -91866.0% | -175.3% | · |
| XLO | $3M | -0.2 | 589.9% | -80.0% | -165.5% | · |
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Source: SEC 10-Q filed Aug 12, 2026