NAUT Nautilus Biotechnology, Inc. - Common Stock

NASDAQ · Life Sciences Tools & Services · View on SEC EDGAR ↗
$0.89
Price · Aug 19, 2026
Fundamentals as of Jul 28, 2026

NAUT Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$0.89
Market Cap
$114M
P/E (TTM)
-1.9
EPS (TTM)
$-0.47
Revenue (TTM)
Div Yield
ROE
-34.9%
Debt/Equity
52W Range
$1 – $4

NAUT Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
EPS $-0.47
6-point trend, +13.0%
2020-12-31 2025-12-31
Free Cash Flow $-52M
5-point trend, -25.2%
2021-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
NAUT
Peer Median
P/E (TTM)
5-point trend, +51.9%
-1.9
17.5
P/B
5-point trend, -11.3%
0.7
1.5
Price / FCF
5-point trend, +69.4%
-2.2

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
NAUT
Peer Median
ROA
5-point trend, -30.7%
-27.2%
-21.2%
ROE
5-point trend, -157.2%
-34.9%
-35.1%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
NAUT
Peer Median
Current Ratio
5-point trend, -77.8%
13.3
6.7
Quick Ratio
5-point trend, -95.1%
1.6

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
NAUT
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
NAUT
Peer Median
EPS (Diluted)
5-point trend, +21.7%
$-0.47

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
NAUT
Peer Median

NAUT Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 8 analysts
  • Strong Buy 3 37.5%
  • Buy 4 50.0%
  • Hold 1 12.5%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

1 analysts · 2026-08-15
Median target $4.00 +347.7%
Mean target $4.00 +347.7%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.03%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.11 $-0.14 0.03%
March 31, 2026 $-0.12 $-0.15 0.03%
Dec. 31, 2025 $-0.11 $-0.14 0.03%
Sept. 30, 2025 $-0.11 $-0.15 0.04%
June 30, 2025 $-0.12 $-0.16 0.04%
March 31, 2025 $-0.13 $-0.15 0.02%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
NAUT $247M -4.1 -34.9%
CDXS $147M -3.3 18.6% -62.5% -82.8%
QSI
MXCT $166M -3.7 -14.5% -135.1% -24.6% 81.2%
QTRX $297M -2.5 1.1% -77.1% -36.4% 46.8%
SEER -1.4 17.0%
RPID -2.8 19.7% -140.3% -107.4%
CSBR $83M -74.5 4.4% -2.0% -30.5%
HYFT
TMO $257.86B 32.7 3.9% 15.0% 13.0%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 10
Annual Income Statement data for NAUT
Metric Trend 202520242023202220212020
R&D Expense 6-point trend, +230.7% $41M $50M $47M $38M $29M $12M
SG&A Expense 6-point trend, +676.8% $26M $31M $29M $26M $21M $3M
Operating Expenses 6-point trend, +324.5% $67M $81M $76M $64M $50M $16M
Other Non-op 6-point trend, +6168.8% $8M $11M $12M $6M $183.0K $125.0K
Income Tax Flat — no change across 6 periods $0 $0 $0 $0 $0 $0
Net Income 6-point trend, -277.8% $-59M $-71M $-64M $-58M $-50M $-16M
EPS (Basic) 6-point trend, +13.0% $-0.47 $-0.56 $-0.51 $-0.46 $-0.60 $-0.54
EPS (Diluted) 6-point trend, +13.0% $-0.47 $-0.56 $-0.51 $-0.46 $-0.60 $-0.54
Shares (Basic) 6-point trend, +334.0% 126,256,583 125,426,509 124,919,144 124,589,555 84,464,081 29,089,778
Shares (Diluted) 6-point trend, +334.0% 126,256,583 125,426,509 124,919,144 124,589,555 84,464,081 29,089,778
Balance Sheet 20
Annual Balance Sheet data for NAUT
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, -66.2% $12M $28M $19M $115M $186M $37M
Prepaid Expense 6-point trend, +178.8% $3M $3M $3M $3M $3M $917.0K
Current Assets 6-point trend, +36.4% $106M $133M $177M $187M $349M $78M
PP&E (Net) 6-point trend, +152.2% $3M $4M $4M $4M $2M $1M
PP&E (Gross) 6-point trend, +335.9% $12M $11M $9M $7M $4M $3M
Accum. Depreciation 6-point trend, +532.0% $8M $7M $5M $3M $2M $1M
Other Non-current Assets 6-point trend, +3.6% $1M $1M $1M $1M $997.0K $1M
Total Assets 6-point trend, +124.8% $191M $243M $306M $350M $398M $85M
Accounts Payable 6-point trend, +100.6% $943.0K $987.0K $2M $1M $2M $470.0K
Accrued Liabilities · · · · · $388.5K
Current Liabilities 6-point trend, +163.5% $8M $8M $9M $7M $6M $3M
Capital Leases 6-point trend, +694.5% $26M $26M $31M $28M $29M $3M
Total Liabilities 6-point trend, +440.7% $34M $34M $40M $35M $35M $6M
Common Stock 6-point trend, +1200.0% $13.0K $13.0K $13.0K $12.0K $12.0K $1.0K
Paid-in Capital 6-point trend, +81356.2% $489M $482M $468M $455M $444M $600.0K
Retained Earnings 6-point trend, -994.9% $-332M $-273M $-202M $-139M $-81M $-30M
AOCI 6-point trend, +8000.0% $243.0K $57.0K $-255.0K $-2M $-184.0K $3.0K
Stockholders' Equity 6-point trend, +628.2% $157M $209M $265M $315M $364M $-30M
Liabilities + Equity 6-point trend, +124.8% $191M $243M $306M $350M $398M $85M
Shares Outstanding 6-point trend, +282.4% 126,469,610 126,106,176 125,068,601 124,865,485 124,303,083 33,069,513
Cash Flow 7
Annual Cash Flow data for NAUT
Metric Trend 202520242023202220212020
Stock-based Comp 6-point trend, +1754.7% $7M $13M $12M $10M $8M $369.0K
Operating Cash Flow 6-point trend, -262.2% $-51M $-59M $-52M $-46M $-39M $-14M
CapEx 6-point trend, +38.7% $1M $2M $2M $2M $2M $921.0K
Investing Cash Flow 6-point trend, +239.3% $35M $66M $-44M $-26M $-139M $-25M
Financing Cash Flow 6-point trend, -99.7% $214.0K $1M $368.0K $562.0K $327M $76M
Net Change in Cash 6-point trend, -141.7% $-15M $8M $-95M $-71M $149M $37M
Free Cash Flow 5-point trend, -25.2% $-52M $-61M $-54M $-48M $-42M ·
Profitability 2
Annual Profitability data for NAUT
Metric Trend 202520242023202220212020
ROA 5-point trend, -30.7% -27.2% -25.8% -19.4% -15.5% -20.8% ·
ROE 5-point trend, -157.2% -34.9% -32.8% -23.5% -18.1% -13.6% ·
Liquidity & Solvency 2
Annual Liquidity & Solvency data for NAUT
Metric Trend 202520242023202220212020
Current Ratio 6-point trend, +296.8% 13.3 17.4 19.4 27.6 60.1 3.4
Quick Ratio 6-point trend, -39.5% 1.6 3.6 2.1 16.9 31.9 2.6
Per Share 4
Annual Per Share data for NAUT
Metric Trend 202520242023202220212020
Book Value / Share 5-point trend, -57.6% $1.24 $1.66 $2.12 $2.52 $2.92 ·
Cash Flow / Share 5-point trend, +13.6% $-0.40 $-0.47 $-0.41 $-0.37 $-0.46 ·
Cash / Share 5-point trend, -93.4% $0.10 $0.22 $0.16 $0.92 $1.49 ·
EPS (TTM) 6-point trend, +13.0% $-0.47 $-0.56 $-0.51 $-0.46 $-0.60 $-0.54
Valuation (TTM) 8
Annual Valuation (TTM) data for NAUT
Metric Trend 202520242023202220212020
Net Income TTM 6-point trend, -277.8% $-59M $-71M $-64M $-58M $-50M $-16M
Market Cap 5-point trend, -61.7% $247M $212M $374M $225M $644M ·
P/E 6-point trend, +79.4% -4.1 -3.0 -5.9 -3.9 -8.6 -20.1
P/B 5-point trend, -11.3% 1.6 1.0 1.4 0.7 1.8 ·
P / Tangible Book 5-point trend, -11.3% 1.6 1.0 1.4 0.7 1.8 ·
P / Cash Flow 5-point trend, +70.4% -4.9 -3.6 -7.2 -4.9 -16.4 ·
P / FCF 5-point trend, +69.4% -4.7 -3.5 -6.9 -4.7 -15.5 ·
Earnings Yield 6-point trend, -383.9% -24.1% -33.3% -17.1% -25.6% -11.6% -5.0%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-59M$-71M$-64M$-58M$-50M
Diluted EPS $-0.47$-0.56$-0.51$-0.46$-0.60
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 13.317.419.427.660.1
Quick Ratio 1.63.62.116.931.9
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-52M$-61M$-54M$-48M$-42M

My Metrics Your personal watchlist — selected rows from Full Fundamentals

📊

Pick the metrics that matter to you — click the ➕ next to any row in Full Fundamentals above.

Your selection is saved and follows you across all tickers.

Institutional owners (13F) 105 filers · $77.6M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
35 (+10 vs prior Q) 18 (+11 vs prior Q) 25 (+10 vs prior Q) 14 (+1 vs prior Q) -7.8M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
PERCEPTIVE ADVISORS LLC $21,755,974 11,634,211 28.05% Shares
a16z Capital Management, L.L.C. $16,947,911 9,063,054 21.85% Shares
Cercano Management LLC $13,413,482 7,172,985 17.29% Shares
VANGUARD CAPITAL MANAGEMENT LLC $4,768,461 2,549,979 6.15% Shares
Comprehensive Financial Management LLC $4,128,248 2,207,619 5.32% Shares
GEODE CAPITAL MANAGEMENT, LLC $2,028,163 1,084,281 2.61% Shares
Clearstead Advisors, LLC $1,669,512 892,787 2.15% Shares
BARCLAYS PLC $1,349,958 721,902 1.74% Shares
RENAISSANCE TECHNOLOGIES LLC $1,291,261 690,514 1.66% Shares
STATE STREET CORP $1,046,280 559,508 1.35% Shares
Clarius Group, LLC $746,131 866,586 0.96% Shares
DIMENSIONAL FUND ADVISORS LP $710,213 379,793 0.92% Shares
VANGUARD FIDUCIARY TRUST CO $660,284 353,093 0.85% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $631,589 337,748 0.81% Shares
VANGUARD GROUP INC $595,776 305,526 0.77% Shares
Qube Research & Technologies Ltd $481,237 257,346 0.62% Shares
HILLMAN CO $374,000 200,000 0.48% Shares
GOLDMAN SACHS GROUP INC $368,498 197,058 0.48% Shares
MILLENNIUM MANAGEMENT LLC $352,925 188,730 0.46% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $336,600 180,000 0.43% Shares
Corient Private Wealth LP $308,154 164,788 0.40% Shares
MARSHALL WACE, LLP $281,972 150,787 0.36% Shares
Crewe Advisors LLC $254,418 136,052 0.33% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $231,289 123,684 0.30% Shares
Point72 Asset Management, L.P. $127,044 67,938 0.16% Shares
Palumbo Wealth Management LLC $123,854 66,232 0.16% Shares
Nuveen, LLC $123,798 66,202 0.16% Shares
Quadrature Capital Ltd $109,505 58,559 0.14% Shares
Y-Intercept (Hong Kong) Ltd $108,744 58,152 0.14% Shares
AMERICAN CENTURY COMPANIES INC $98,528 52,689 0.13% Shares
CITIZENS FINANCIAL GROUP INC/RI $93,500 50,000 0.12% Shares
HSBC HOLDINGS PLC $91,233 49,449 0.12% Shares
DEUTSCHE BANK AG\ $90,729 48,518 0.12% Shares
Bank of New York Mellon Corp $89,106 47,650 0.11% Shares
Caprock Group, LLC $88,058 47,090 0.11% Shares
Ashton Thomas Private Wealth, LLC $84,150 45,000 0.11% Shares
Fayez Sarofim & Co $84,150 45,000 0.11% Shares
WELLS FARGO & COMPANY/MN $78,555 42,008 0.10% Shares
SEI INVESTMENTS CO $72,262 38,643 0.09% Shares
RHUMBLINE ADVISERS $68,374 36,567 0.09% Shares
Presidio Capital Management, LLC $64,822 34,664 0.08% Shares
AXQ CAPITAL, LP $63,855 34,147 0.08% Shares
CAPTRUST FINANCIAL ADVISORS $63,580 34,000 0.08% Shares
Squarepoint Ops LLC $63,105 33,746 0.08% Shares
BlackRock, Inc. $57,422 30,707 0.07% Shares
Badgley Phelps Wealth Managers, LLC $56,100 30,000 0.07% Shares
BANK OF AMERICA CORP /DE/ $53,216 28,458 0.07% Shares
JPMORGAN CHASE & CO $53,041 29,632 0.07% Shares
Catalyst Funds Management Pty Ltd $49,256 26,340 0.06% Shares
Callan Family Office, LLC $48,564 25,970 0.06% Shares
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $42,819 22,898 0.06% Shares
LAKE STREET ADVISORS GROUP, LLC $38,240 22,762 0.05% Shares
CITIGROUP INC $37,778 20,202 0.05% Shares
Invesco Ltd. $37,080 19,829 0.05% Shares
CITADEL ADVISORS LLC $37,026 19,800 0.05% Put option
Police & Firemen's Retirement System of New Jersey $35,498 18,983 0.05% Shares
CITADEL ADVISORS LLC $35,156 18,800 0.05% Call option
Engineers Gate Manager LP $33,623 17,980 0.04% Shares
UBS Group AG $31,996 17,110 0.04% Shares
Vanguard Global Advisers, LLC $31,055 16,607 0.04% Shares
TD Waterhouse Canada Inc. $29,280 16,000 0.04% Shares
NEW YORK STATE COMMON RETIREMENT FUND $26,180 14,000 0.03% Shares
Balyasny Asset Management L.P. $24,654 13,184 0.03% Shares
Vanguard Capital Wealth Advisors $24,310 13,000 0.03% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $22,580 12,075 0.03% Shares
INTECH INVESTMENT MANAGEMENT LLC $22,173 11,857 0.03% Shares
BNP PARIBAS FINANCIAL MARKETS $21,494 11,494 0.03% Shares
Garde Capital, Inc. $20,570 11,000 0.03% Shares
BLAIR WILLIAM & CO/IL $18,700 10,000 0.02% Shares
Rockefeller Capital Management L.P. $17,578 9,400 0.02% Shares
GROUP ONE TRADING LLC $15,328 8,197 0.02% Shares
NORTHERN TRUST CORP $14,513 7,761 0.02% Shares
Point72 Asia (Singapore) Pte. Ltd. $13,747 16,271 0.02% Shares
BFSG, LLC $12,529 6,700 0.02% Shares
Madrona Venture Group, LLC $11,741 6,020,770 0.02% Shares
Legal & General Group Plc $9,058 4,844 0.01% Shares
Ameritas Investment Partners, Inc. $8,439 4,513 0.01% Shares
Russell Investments Group, Ltd. $7,435 3,976 0.01% Shares
FMR LLC $6,700 3,583 0.01% Shares
OSAIC HOLDINGS, INC. $5,753 3,078 0.01% Shares
Federation des caisses Desjardins du Quebec $5,610 3,000 0.01% Shares
Nuveen Asset Management, LLC $5,509 3,279 0.01% Shares
Tower Research Capital LLC (TRC) $5,286 2,827 0.01% Shares
ROYAL BANK OF CANADA $3,000 1,565 0.00% Shares
SIMPLEX TRADING, LLC $2,038 1,090 0.00% Shares
ACADIAN ASSET MANAGEMENT LLC $1,965 1,055,461 0.00% Shares
Sterling Capital Management LLC $1,724 922 0.00% Shares
SENTINEL TRUST CO LBA $1,402 750,000 0.00% Shares
MORGAN STANLEY $1,262 675 0.00% Shares
GILL CAPITAL PARTNERS, LLC $970 250 0.00% Shares
CITADEL ADVISORS LLC $935 500 0.00% Shares
HRT FINANCIAL LP $675 361,073 0.00% Shares
Point72 (DIFC) Ltd $667 789 0.00% Shares
Guerra Advisors Inc $338 400 0.00% Shares
Caitong International Asset Management Co., Ltd $223 119 0.00% Shares
GSA CAPITAL PARTNERS LLP $189 101,112 0.00% Shares
SBI Securities Co., Ltd. $187 100 0.00% Shares
Allworth Financial LP $135 72 0.00% Shares
CWM, LLC $113 29 0.00% Shares
Virtu Financial LLC $93 49,943 0.00% Shares

Company insiders 10 insiders · 1 officers · 7 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Adam Leo Stone Chief Executive Officer Aug. 11, 2020 J 499,000 0 0 $0
Melissa B, Epperly Director June 18, 2026 A 0 0 $0
Karen Akinsanya Director June 18, 2026 A 0 0 $0
Matthew L. Posard Director June 18, 2026 A 0 0 $0
Matthew S Mcilwain Director June 18, 2026 A 459,075 0 0 $0
Farzad Nazem Director June 18, 2026 A 0 0 $0
Michael Seth Altman Director June 14, 2024 A 499,000 0 0 $0
ARYA Sciences Holdings III 10% owner Aug. 11, 2020 J 499,000 0 0 $0
Sujal Patel March 4, 2026 P 10,366,721 3 0 $200,085
Gwen E Weld March 2, 2026 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 6 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Perceptive Advisors LLC, Joseph Edelman, Perceptive Life Sciences Master Fund, Ltd., C2 Life Sciences LLC ×6 filings Aug. 14, 2026 9.10% Amendment SEC
AH Bio Fund II, L.P., AH Equity Partners Bio II, L.L.C., Andreessen Horowitz LSV Fund II, L.P., AH Equity Partners LSV II, L.L.C., Marc L. Andreessen, Benjamin A. Horowitz ×2 filings June 30, 2026 7.10% Amendment SEC
Parag Mallick ×3 filings March 4, 2026 17.60% Amendment SEC
Sujal Patel ×4 filings March 4, 2026 16.30% Amendment SEC
McIlwain, Matthew S. Aug. 26, 2021 Initial filing Passive investment SEC
AH Bio Fund II, L.P. (“AH Bio II”), AH Bio Fund II-B, L.P. (“AH Bio II-B”), AH Equity Partners Bio II, L.L.C. (“AH Equity Bio II”), Andreessen Horowitz LSV Fund II, L.P. (“AH LSV II”), Andreessen Horowitz LSV Fund II-B, L.P. (“AH LSV II-B”), Andreessen Horowitz LSV Fund II-Q, L.P. (“AH LSV II-Q”), AH Equity Partners LSV II, L.L.C. (“AH Equity LSV II”), Marc Andreessen (“Andreessen”), Benjamin Horowitz (“Horowitz”) June 30, 2021 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 15 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
VTWV · VANGUARD SCOTTSDALE FUNDS 0.01% 39,046 SH Aug. 8, 2026 Daily
IWC · iShares Trust 0.01% 166,544 SH Aug. 8, 2026 Daily
AVSC · AMERICAN CENTURY ETF TRUST 0.00% 31,556 NS May 31, 2026 N-PORT
OMFS · Invesco Exchange-Traded Self-Indexe… 0.00% 9,215 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.00% 383,593 SH Aug. 8, 2026 Daily
DFAS · Dimensional ETF Trust 0.00% 67,544 NS April 30, 2026 N-PORT
IWM · iShares Trust 0.00% 1,051,130 SH Aug. 8, 2026 Daily
DCOR · Dimensional ETF Trust 0.00% 5,271 NS April 30, 2026 N-PORT
IWO · iShares Trust 0.00% 65,446 SH Aug. 8, 2026 Daily
DFAC · Dimensional ETF Trust 0.00% 71,084 NS April 30, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 543,262 SH Aug. 8, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 1,930,610 SH Aug. 8, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.00% 287,515 SH Aug. 8, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.00% 4,846 SH Aug. 8, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 6,341 SH Aug. 8, 2026 Daily