CDXS Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $1.36
Market Cap (MRQ) $124M
P/E (TTM) -4.2
EPS (TTM) $-0.32
Revenue (TTM) $78M
ROE (TTM) -69.4%
Debt/Equity (MRQ) 1.2
52W Range $1–$3

CDXS Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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About Codexis, Inc. - Common Stock Company overview from Wikipedia

05 · wikidata

Codexis, Inc. is a protein engineering company that develops enzymes for pharmaceutical, food and medical applications.

History

Codexis is based in Redwood City, CA and was incorporated in 2002. It went public in April 2010 on NASDAQ, and in October, acquired Maxygen's MolecularBreeding technology portfolio.

Pharmaceutical

Codexis won the Presidential Green Chemistry Challenge Award from the U.S. Environmental Protection Agency (EPA) in 2006 for its work on a building block of Lipitor. It then won a second time in 2010 for its work with Merck & Co. on the active ingredient in Januvia.

Nutrition

In 2017, the company entered a partnership with Tate & Lyle to provide research and development for the production of new ingredients. That same year, Codexis announced a collaboration with Nestle to provide enzymes for metabolic disorders.

Biotherapeutics

In 2017, Codexis developed a recombinant phenylalanine ammonia-lyase (PAL) enzyme, to act as a substitute phenylalanine hydroxylase (PAH) enzyme for people who suffer from phenylketonuria. The enzyme was in-licensed by Nestle Health Sciences.

In 2020, Takeda Pharmaceutical announced a collaboration with Codexis to research and create gene therapies for rare diseases, including lysosomal storage disorders.

Life science

In June 2020, they announced a partnership with Molecular Assemblies to engineer enzymes for DNA synthesis.

Technology

Codexis uses directed evolution to develop its enzymes. Using this method, scientists genetically engineer genes, then screen the enzymes produced to see if it creates the properties needed for a specific reaction. Their protein engineering platform, called CodeEvolver, uses machine learning and high-throughput experimentation to learn protein sequence changes and their impacts on protein function.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

sectorHealthcare industryLife Sciences Tools & Services employees146 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$70M
2016-12-31 → 2025-12-31
EPS$-0.50
2019-12-31 → 2025-12-31
Free Cash Flow$-24M
2016-12-31 → 2025-12-31
Net margin-39.6%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend CDXS 5Y avg Peer Median Verdict
P/E (TTM) -4.25Y avg ≈-23.0 ≈-23.0 · ·
P/S (TTM) 1.65Y avg ≈6.7 ≈6.7 4.2 Undervalued
P/B (MRQ) 3.85Y avg ≈5.1 ≈5.1 0.9 Overvalued
EV / EBITDA (TTM) -4.9 · · ·
Price / FCF (TTM) -10.25Y avg ≈2.7 ≈2.7 · ·
Price / Cash Flow (TTM) -11.95Y avg ≈-27.0 ≈-27.0 · ·
EV / Revenue (TTM) 1.4 · · ·
EV / FCF (TTM) -9.1 · · ·
Price / Tangible Book 2.65Y avg ≈5.3 ≈5.3 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 15.7%
Next Report Nov 04, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 11, 2026 $-0.13 $-0.14 7.7%
March 31, 2026 May 12, 2026 $-0.10 $-0.14 28.3%
Dec. 31, 2025 $0.11 $-0.04 357.0%
Sept. 30, 2025 $-0.22 $-0.15 -45.2%
June 30, 2025 $-0.16 $-0.19 16.8%
March 31, 2025 $-0.25 $-0.24 -3.3%
Dec. 31, 2024 $-0.13 $-0.04 -251.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 16
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $70M$59M$70M$139M$105M$69M$68M$61M$50M$49M$42M$35M
Cost of Revenue $9M$16M$13M$38M$22M$14M$16M$13M$14M$10M$7M$10M
R&D Expense $52M$46M$59M$80M$56M$44M$34M$30M$30M$22M$21M$23M
SG&A Expense $47M$55M$53M$52M$49M$35M$32M$29M$29M$25M$22M$22M
Operating Expenses $112M$118M$138M$173M$127M$93M$81M$72M$73M$57M$50M$54M
Operating Income $-42M$-59M$-68M$-35M$-23M$-24M$-13M$-11M$-23M$-9M$-8M$-19M
Interest Income $3M$4M$4M$1M$459.0K$405.0K$1M$671.0K$147.0K$60.0K$19.0K$18.0K
Other Non-op $-5M$-10M$-12M$124.0K$1M$-156.0K$-656.0K$-291.0K$-92.0K$-94.0K··
Pretax Income $-44M$-65M$-76M$-33M$-21M$-24M$-12M$-11M$-23M$-9M$-8M$-19M
Income Tax $47.0K$34.0K$69.0K$276.0K$189.0K$339.0K$17.0K$-37.0K$81.0K$-40.0K$-338.0K$-256.0K
Net Income $-44M$-65M$-76M$-34M$-21M$-24M$-12M$-11M$-23M$-9M$-8M$-19M
EPS (Basic) $-0.50$-0.89$-1.12$-0.51$-0.33$-0.40$-0.21·····
EPS (Diluted) $-0.50$-0.89$-1.12$-0.51$-0.33$-0.40$-0.21·····
Shares (Basic) 87,142,00073,408,00068,131,00065,344,00064,568,00059,360,00056,525,000·····
Shares (Diluted) 87,142,00073,408,00068,131,00065,344,00064,568,00059,360,00056,525,000·····
EBITDA $-36M$-54M$-68M$-35M$-23M$-24M$-13M$-11M$-23M$-9M$-8M$-19M
Balance Sheet 29
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $51M$19M$65M$114M$117M$149M$90M$53M$31M$19M$23M$26M
Short-term Investments $27M$54M$0·········
Receivables ··$10M$32M$25M$14M$9M$12M$11M$6M$7M$4M
Inventory $2M$2M$3M$2M$1M$964.0K$371.0K$589.0K$1M$825.0K$992.0K$1M
Prepaid Expense $6M$4M$5M$5M$6M$3M$3M$1M$984.0K$1M$1M$1M
Other Current Assets $500.0K$500.0K$600.0K$700.0K········
Current Assets $97M$99M$93M$163M$162M$184M$114M$68M$45M$27M$33M$33M
PP&E (Net) $13M$14M$15M$23M$21M$10M$6M$5M$3M$2M$3M$4M
PP&E (Gross) $58M$55M$55M$62M$57M$43M$40M$38M$35M$34M$35M$37M
Accum. Depreciation $45M$41M$39M$40M$36M$33M$33M$33M$32M$32M$32M$31M
Goodwill $2M$2M$2M$3M$3M$3M$3M$3M$3M$3M$3M$3M
Intangibles ·········$0$3M$6M
Other Non-current Assets $883.0K$1M$1M$350.0K$276.0K$294.0K$178.0K$1M$302.0K$259.0K$310.0K$294.0K
Total Assets $148M$149M$137M$250M$246M$222M$149M$79M$54M$36M$45M$48M
Accounts Payable $2M$3M$6M$3M$3M$3M$3M$3M$4M$4M$3M$5M
Accrued Liabilities $3M$6M$5M$15M$13M$10M$7M$5M$4M$2M$2M$3M
Current Liabilities $25M$24M$36M$49M$33M$25M$15M$18M$25M$12M$15M$14M
Capital Leases $30M$28M$12M$38M$44M$22M$25M$61.0K$302.0K···
Other Non-current Liabilities $1M$1M$1M$1M$1M$1M$1M$1M$2M$2M$2M$3M
Total Liabilities $97M$82M$50M$106M$82M$52M$44M$23M$29M$17M$22M·
Long-term Debt $40M$29M··········
Total Debt $40M$29M······$302.0K···
Common Stock $9.0K$8.0K$7.0K$6.0K$6.0K$6.0K$6.0K$5.0K$5.0K$4.0K$4.0K$4.0K
Paid-in Capital $657M$630M$584M$566M$552M$537M$448M$387M$340M$311M$306M$302M
Retained Earnings $-607M$-563M$-498M$-421M$-388M$-366M$-342M$-330M$-315M$-292M$-284M$-276M
AOCI $8.0K$52.0K$0····$0$-472.0K$0$405.0K$-142.0K
Stockholders' Equity $51M$67M$87M$145M$164M$170M$106M$56M$25M$19M$23M$26M
Liabilities + Equity $148M$149M$137M$250M$246M$222M$149M$79M$54M$36M$45M$48M
Shares Outstanding 90,478,00081,850,00069,905,00065,811,00065,109,00064,283,00058,877,00054,065,00048,365,00041,255,00040,343,00039,563,000
Cash Flow 17
Metric Trend 202520242023202220212020201920182017201620152014
D&A $5M$5M$6M$5M········
Stock-based Comp $10M$13M$10M$15M$12M$8M$7M$8M$7M$6M$5M$5M
Deferred Tax $-3.0K$-2.0K$0$-7.0K$-9.0K$-8.0K$-6.0K$-29.0K$12.0K$-31.0K$-330.0K$110.0K
Amort. of Intangibles ·······$0$0$3M$3M$3M
Restructuring $3M$0$3M$3M$0$0······
Other Non-cash $10M$-2M··········
Operating Cash Flow $-19M$-49M$-53M$11M$-14M$-16M$-13M$-14M$-9M$-2M$-433.0K$321.0K
CapEx $4M$4M$4M$8M$14M$4M$4M$3M$985.0K$888.0K$1M$302.0K
Investing Cash Flow $24M$-57M$-5M$-14M$-21M$-6M$-4M$-3M$-983.0K$-846.0K$-1M$5M
Debt Issued $10M$30M$0$0········
Net Debt Issued $10M$30M··········
Stock Issued $17M$31M$9M$0$0$86M$0$37M$24M$0$0$9.0K
Net Stock Activity $17M$31M$9M$0$0$86M$50M·$24M$0$0$9.0K
Financing Cash Flow $28M$61M$8M$-575.0K$4M$81M$54M$39M$22M$-490.0K$-2M$-611.0K
Net Change in Cash $32M$-46M$-49M$-3M$-32M$59M$38M$22M$12M$-3M$-3M$4M
Taxes Paid ·$17.0K$194.0K$100.0K$102.0K$312.0K$5.0K$5.0K$32.0K$5.0K$8.0K$15.0K
Free Cash Flow $-24M$-54M$-57M$3M$-28M$-20M$-16M$-17M$-10M$-4M$-2M$19.0K
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin -59.3%-98.6%-97.0%-25.2%-21.7%-34.6%-18.3%-18.6%-45.9%-17.5%-18.6%-54.1%
Net Margin -62.5%-110.0%-108.7%-24.2%-20.3%-34.8%-17.4%-17.9%-46.0%-17.5%-18.1%-54.0%
Pretax Margin -62.4%-109.9%-108.6%-24.0%-20.1%-34.3%-17.4%-18.0%-45.8%-17.6%-18.9%-54.7%
EBITDA Margin -51.8%-90.3%-97.0%-25.2%-21.7%-34.6%-18.3%-18.6%-45.9%-17.5%-18.6%-54.1%
ROA -29.6%-45.7%-39.4%-13.5%-9.1%-13.0%-10.4%-16.4%-51.5%-21.3%-16.3%-35.7%
ROE -82.8%-93.0%-85.6%-22.5%-12.8%-18.4%-11.5%-19.6%-98.6%-40.8%-30.8%-56.3%
ROIC -46.1%-61.1%-78.7%-24.3%-13.9%-14.3%-11.9%-20.0%-92.8%-44.6%-32.5%-71.7%
Liquidity & Solvency 4
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 3.84.22.63.34.97.47.43.81.82.22.22.4
Quick Ratio 3.13.12.13.04.26.56.53.61.72.02.12.2
Debt / Equity 0.80.4······0.0···
LT Debt / Equity 0.80.4······0.0···
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.50.40.40.60.40.40.60.91.11.20.90.7
Inventory Turnover 5.27.35.423.920.920.632.615.515.410.75.56.7
Receivables Turnover ··3.34.95.46.06.75.35.67.47.57.6
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $0.56$0.82$1.24$2.20$2.52$2.65$1.79$1.03$0.51$0.46$0.57$0.67
Revenue / Share $0.81$0.81$1.03$2.12$1.62·······
Cash Flow / Share $-0.22$-0.67$-0.77$0.17$-0.22·······
Cash / Share $0.56$0.24$0.93$1.73$1.79$2.32$1.54$0.97$0.65$0.47$0.58$0.67
EPS (TTM) $-0.50$-0.89$-1.12$-0.51$-0.33$-0.40$-0.21·····
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 18.6%-15.4%-49.4%32.3%51.7%·······
Revenue CAGR 3Y -20.2%-17.3%0.52%·········
Revenue CAGR 5Y 0.38%···········
Valuation (TTM) 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $70M$59M$70M$139M$105M$69M$68M$61M$50M$49M$42M$35M
Net Income TTM $-44M$-65M$-76M$-34M$-21M$-24M$-12M$-11M$-23M$-9M$-8M$-19M
Market Cap $147M$390M$213M$307M$2.04B$1.40B$941M$912M$404M$190M$171M$100M
Enterprise Value $109M$346M······$373M···
P/E -3.3-5.4-2.7-9.1-94.8-54.6-76.1·····
P/S 2.16.63.02.219.420.313.815.08.13.94.12.8
P/B 2.95.82.52.112.48.28.916.216.59.97.53.8
P / Tangible Book 3.16.12.52.212.68.4······
P / Cash Flow -7.6-7.9-4.127.2-142.7-85.2-75.0-64.7-46.1-70.3-394.1310.6
P / FCF -6.2-7.3-3.7103.0-72.5-69.4-57.8-54.1-41.4-52.9-104.65247.3
EV / EBITDA -3.0-6.5······-16.2···
EV / FCF -4.6-6.4······-38.3···
EV / Revenue 1.65.8······7.5···
Earnings Yield -30.7%-18.7%-36.7%-10.9%-1.1%-1.8%-1.3%·····

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $70M $59M $70M $139M $105M
Operating Margin % -59.3% -98.6% -97.0% -25.2% -21.7%
Net Income $-44M $-65M $-76M $-34M $-21M
Diluted EPS $-0.50 $-0.89 $-1.12 $-0.51 $-0.33

Institutional owners (13F) 155 filers · $154.0M total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 155
Value held $154.0M
New positions 29
Exited positions 11
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
29 (-4 vs prior Q) 11 (-10 vs prior Q) 61 (+13 vs prior Q) 36 (+4 vs prior Q) +3.0M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BlackRock, Inc. $16,462,635 7,284,352 10.69% Shares
Opaleye Management Inc. $15,334,100 6,785,000 9.96% Shares
Aberdeen Group plc $15,300,096 6,769,954 9.94% Shares
MILLENNIUM MANAGEMENT LLC $12,541,054 5,549,139 8.15% Shares
Telemark Asset Management, LLC $8,692,889 3,846,411 5.65% Shares
AMERIPRISE FINANCIAL INC $8,609,334 3,809,440 5.59% Shares
Nantahala Capital Management, LLC $8,189,365 3,623,613 5.32% Shares
VANGUARD CAPITAL MANAGEMENT LLC $8,174,666 3,617,109 5.31% Shares
VANGUARD GROUP INC $8,054,714 4,941,542 5.23% Shares
GEODE CAPITAL MANAGEMENT, LLC $4,887,990 2,162,393 3.17% Shares
STATE STREET CORP $3,970,400 1,756,814 2.58% Shares
D. E. Shaw & Co., Inc. $3,032,952 1,342,014 1.97% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $3,006,263 1,330,205 1.95% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $2,954,206 1,307,171 1.92% Shares
Assenagon Asset Management S.A. $2,888,746 1,278,206 1.88% Shares
AQR CAPITAL MANAGEMENT LLC $1,910,675 845,431 1.24% Shares
TWO SIGMA INVESTMENTS, LP $1,574,314 696,599 1.02% Shares
NORTHERN TRUST CORP $1,543,444 682,940 1.00% Shares
FRANKLIN RESOURCES INC $1,533,726 678,640 1.00% Shares
MORGAN STANLEY $1,467,125 649,170 0.95% Shares
VANGUARD FIDUCIARY TRUST CO $1,313,191 581,058 0.85% Shares
Man Group plc $1,278,240 565,593 0.83% Shares
Post Resch Tallon Group Inc. $1,273,460 563,478 0.83% Shares
PERKINS CAPITAL MANAGEMENT INC $1,188,986 526,100 0.77% Shares
FMR LLC $1,081,371 478,483 0.70% Shares
GOLDMAN SACHS GROUP INC $982,929 434,924 0.64% Shares
ALGERT GLOBAL LLC $973,857 430,910 0.63% Shares
Nuveen, LLC $886,524 392,267 0.58% Shares
TUDOR INVESTMENT CORP ET AL $808,910 357,925 0.53% Shares
DIMENSIONAL FUND ADVISORS LP $708,690 313,386 0.46% Shares
Russell Investments Group, Ltd. $696,292 308,095 0.45% Shares
PLATINUM INVESTMENT MANAGEMENT LTD $597,689 264,464 0.39% Shares
ROYAL BANK OF CANADA $594,000 262,926 0.39% Shares
Potomac Capital Management, Inc. $587,600 260,000 0.38% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $547,397 242,211 0.36% Shares
XTX Topco Ltd $543,817 240,627 0.35% Shares
BANK OF AMERICA CORP /DE/ $543,568 240,517 0.35% Shares
UBS Group AG $542,190 239,907 0.35% Shares
Bank of New York Mellon Corp $510,849 226,039 0.33% Shares
CITADEL ADVISORS LLC $432,971 191,580 0.28% Shares
Invesco Ltd. $366,732 162,271 0.24% Shares
Cubist Systematic Strategies, LLC $359,610 147,381 0.23% Shares
BARCLAYS PLC $350,920 155,274 0.23% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $334,595 148,051 0.22% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $284,552 125,908 0.18% Shares
STRS OHIO $273,460 121,000 0.18% Shares
JANE STREET GROUP, LLC $273,042 120,815 0.18% Shares
MARSHALL WACE, LLP $264,726 117,135 0.17% Shares
Stonepine Capital Management, LLC $247,836 109,662 0.16% Shares
RHUMBLINE ADVISERS $233,449 103,301 0.15% Shares

Show all 155 institutional owners →

Activists & 5%+ owners 3 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
John Nicols Feb. 16, 2021 · Initial filing Passive investment SEC
– I.RS. IDENTIFICATION NO. OF ABOVE PERSON RAÍZEN ENERGIA S.A., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON SHELL BRAZIL HOLDING B.V., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON ROYAL DUTCH SHELL PLC, – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN S.A. INDUSTRIA E COMÉRCIO, – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN INVESTIMENTOS E PARTICIPAÇÕES S.A., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN LIMITED ×2 filings May 26, 2015 · Initial filing · SEC
– I.RS. IDENTIFICATION NO. OF ABOVE PERSON RAIZEN ENERGIA PARTICIPA Ç Õ ES S.A., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON ISPAGNAC PARTICIPA Ç Õ ES LTDA., – I.RS. IDENTIFICATION NO. OF ABOVE PERSON ROYAL DUTCH SHELL PLC, – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN S.A. INDUSTRIA E COM É RCIO, – I.RS. IDENTIFICATION NO. OF ABOVE PERSON COSAN LIMITED June 7, 2011 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 44 insiders · 19 officers · 22 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Alison Moore President and CEO Feb. 23, 2026 A 250,506 0 2 $-20,672
Peter M Strumph Interim President and CEO June 1, 2012 A 60,756 0 0 $0
Alan Shaw President and CEO Dec. 16, 2011 S 202,000 0 0 $0
Georgia Erbez Chief Financial Officer and Chief Business Officer Feb. 23, 2026 A 66,810 0 2 $-20,610
Sriram Ryali Chief Financial Officer Jan. 1, 2024 A 175,791 0 0 $0
Gordon Sangster SVP & Chief Financial Officer March 21, 2019 M 134,453 0 0 $0
David D O'Toole SVP & Chief Financial Officer Sept. 4, 2013 F 110,687 0 0 $0
Brian Paul Dowd Interim CFO June 1, 2012 A 28,310 0 0 $0
Robert J Lawson SVP and CFO May 11, 2011 P 44,000 0 0 $0
Kevin Norrett Chief Operating Officer Feb. 5, 2025 A 177,327 0 0 $0
Stefan Lutz Chief Scientific Officer Feb. 23, 2026 A 130,421 0 3 $-17,853
Margaret Nell Fitzgerald Chief Legal and Compliance Officer Jan. 1, 2024 A 133,770 0 0 $0
James Lalonde SVP, R&D May 14, 2019 M 133,402 0 0 $0
Michael D. Aldridge Senior Vice President, Corporate & Strategic Development May 17, 2018 M 0 0 0 $0
Douglas T. Sheehy EVP, Chief Administrative Officer, General Counsel & Secretary March 5, 2016 F 247,617 0 0 $0
Matthew Tobin SVP, Research & Development May 16, 2013 M 78,707 0 0 $0
David L. Anton SVP, BioIndustrials Feb. 10, 2013 F 93,777 0 0 $0
Seufer-Wasserthal Peter SVP, Pharmaceuticals Jan. 24, 2013 A 93,064 0 0 $0
Joseph J. Sarret SVP and CBO March 7, 2012 A 74,000 0 0 $0
Raymond De Vre Director June 17, 2026 A 84,811 0 2 $-8,633
Esther Martinborough Director June 17, 2026 A 129,036 0 0 $0
Christos Richards Director June 17, 2026 A 85,133 0 0 $0
Cynthia Collins Director June 17, 2026 A 112,157 0 0 $0
Stephen George Dilly Director June 17, 2026 A 727,053 0 0 $0
Rahul Singhvi Director June 17, 2026 A 137,052 0 0 $0
David V Smith Director June 17, 2026 A 105,705 0 0 $0
PARKER H STEWART Director June 17, 2026 A 143,583 0 0 $0
Dennis P Wolf Director Nov. 21, 2025 S 138,951 0 1 $-13,965
Byron L Dorgan Director June 11, 2024 A 223,581 0 0 $0
Jennifer Aaker Director June 13, 2023 A 66,211 0 0 $0
John J Nicols Director April 18, 2023 M 783,965 0 0 $0
Patrick Y Yang Director June 14, 2022 A 53,785 0 0 $0
Bernard J Kelley Director Aug. 10, 2021 M 206,136 0 0 $0
Thomas R Baruch Director June 12, 2020 S 33,093 0 0 $0
Pam P. Cheng Director June 11, 2019 A 69,589 0 0 $0
Kathleen Sereda Glaub Director June 11, 2019 A 68,481 0 0 $0
Alexander Karsner Director Jan. 2, 2014 A 78,519 0 0 $0
Bruce A Pasternack Director Aug. 24, 2010 P 10,000 0 0 $0
James R Sulat Director April 27, 2010 J 5,957,108 0 0 $0
Opaleye Management Inc. 10% owner Dec. 1, 2025 S 179,989 0 27 $-7,596,890
Brazil Holding B.V. Shell 10% owner May 31, 2011 J 5,573,319 0 0 $0
Equilon Enterprises LLC 10% owner May 20, 2011 J 5,573,319 0 0 $0
MAXYGEN INC 10% owner Dec. 14, 2010 J 524,643 0 0 $0
Dean Ross Taylor JR · Feb. 7, 2023 F 38,554 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 19 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
QQQS · Invesco Exchange-Traded Fund Trust … 0.42% 70,133 SH Oct. 2, 2026 Daily
IWC · iShares Trust 0.03% 288,891 SH Sept. 11, 2026 Daily
IBB · iShares Trust 0.01% 766,290 SH Sept. 11, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 496,936 SH Aug. 19, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 78,444 SH Aug. 19, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.01% 7,738 SH Oct. 1, 2026 Daily
IWO · iShares Trust 0.01% 696,097 SH Sept. 11, 2026 Daily
IWM · iShares Trust 0.00% 2,244,630 SH Sept. 11, 2026 Daily
RSSL · Global X Funds 0.00% 41,308 NS July 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.00% 69,999 SH Oct. 2, 2026 Daily
DFAS · Dimensional ETF Trust 0.00% 52,788 NS July 31, 2026 N-PORT
IWV · iShares Trust 0.00% 17,106 SH Sept. 3, 2026 Daily
DFAC · Dimensional ETF Trust 0.00% 19,277 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 1,729 NS July 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.00% 895,869 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 2,633,770 SH Aug. 19, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.00% 9,454 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 6,744 SH Aug. 19, 2026 Daily
IWN · iShares Trust · 129,318 SH Sept. 11, 2026 Daily

CDXS Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 13 analysts BUY
Median target $5.00 +267.6%
4 30.8% Strong Buy
6 46.2% Buy
3 23.1% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

7 analysts · 2026-10-01

Mean target $6.14 +351.7%

← Below all targets Current price $1.36
Low$2.00 Mean$6.14 High$11.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CDXS $147M -3.3 18.6% -62.5% -82.8% ·
LAB $495M -6.4 -6.2% -87.8% -17.6% 49.9%
QSI · · · · · ·
LFCR $249M -5.3 0.47% -30.0% -461.3% 31.3%
NAUT $247M -4.1 · · -34.9% ·
QTRX $297M -2.5 1.1% -77.1% -36.4% 46.8%
SEER · -1.4 17.0% · · ·
MXCT $166M -3.7 -14.5% -135.1% -24.6% 81.2%
CSBR $83M -74.5 4.4% -2.0% -30.5% ·
HYFT · · · -89.7% -78.9% 58.8%
CIRC · · · · · ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 11, 2026