SRPT Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $17.50
Market Cap (MRQ) $1.85B
P/E (TTM) -10.9
EPS (TTM) $-1.60
Revenue (TTM) $1.97B
ROE (TTM) -9.5%
52W Range $15–$25

SRPT Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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Stock splits 1
Ex-date Split Type
July 12, 2012 1-for-6 Reverse

About Sarepta Therapeutics, Inc. - Common Stock Company overview from Wikipedia

05 · wikidata

Sarepta Therapeutics, Inc. is a medical research and drug development company with corporate offices and research facilities in Cambridge, Massachusetts, United States. Incorporated in 1980 as AntiVirals, shortly before going public the company changed its name from AntiVirals to AVI BioPharma soon with stock symbol AVII and in July 2012 changed name from AVI BioPharma to Sarepta Therapeutics and SRPT respectively. As of 2023, the company has four approved drugs.

History

Sarepta started in Corvallis, Oregon on January 1, 1980 and was originally named Antivirals Inc. After occupying several research laboratory spaces in Corvallis, the company opened a production laboratory in Corvallis in February 2002 and was renamed AVI BioPharma Inc. The company made headlines in 2003 when it announced work on treatments for severe acute respiratory syndrome (SARS) and the West Nile virus. In July 2009, the company announced they would move their headquarters from Portland, Oregon, north to Bothell, Washington, near Seattle. At that time, the company led by president and CEO Leslie Hudson had 83 employees and quarterly revenues of $3.2 million. AVI had yet to turn a profit and had not yet developed any commercial products as of July 2009. The company lost $19.7 million in the second quarter of 2009, and then won an $11.5 million contract with the U.S. Department of Defense's Defense Threat Reduction Agency in October 2009. By this time, the company had completed its headquarters move to Bothell.

In 2012, the company moved a second time, to Cambridge, Massachusetts. At the time, CEO Chris Garabedian indicated the move was motivated by the need to recruit expertise in rare diseases. The Corvallis laboratory facility was closed in 2016.

In June 2017, Sarepta Therapeutics appointed former Allergan executive Doug Ingram as its new CEO to replace Edward Kaye who had announced plans to step down earlier that year.

In February 2019, Sarepta acquired five gene therapy candidates for $165 million after one of them, MYO-101, produced results with a new gene therapy candidate for patients with Limb-Girdle muscular dystrophy; two months after receiving a single treatment, muscles from all three patients were producing the protein they couldn't make on their own. In 2019, the FDA rejected a Serepta Duchenne muscular dystrophy drug before reversing course 3 months later.

The company opened a new Genetic Therapies Center of Excellence in Columbus, Ohio in October, 2021 in order to dramatically advance research into therapeutics for several muscular dystrophies that had begun at Nationwide Children's Hospital several years earlier. As of 2022, there are three FDA-approved DMD drugs in Sarepta Therapeutics' portfolio. In January 2023, Sarepta partnered with Catalent to manufacture delandistrogene moxeparvovec (SRP-9001).

In June 2023, the FDA approved Sarepta Therapeutics’ fourth therapy, delandistrogene moxeparvovec-rokl, the first gene therapy to treat Duchenne muscular dystrophy (DMD). The product was approved under the accelerated approval pathway for 4-5 year olds with a confirmed DMD diagnosis. Accelerated approval requires that the product be studied further to verify its clinical benefit.

In July 2025, Sarepta announced plans to lay off 500 employees, about 36% of its workforce, following the deaths of two patients linked to its Duchenne muscular dystrophy gene therapy, ELEVIDYS. The layoffs are part of a restructuring effort expected to generate around $400 million in cost savings by 2026.

Products

Its primary products are based on Morpholino oligomers (PMOs), synthetic nucleic acid analogs that were conceived of by James Summerton and invented by Summerton with Dwight Weller, originally developed under the name NeuGene Antisense. Since morpholino oligomers can form sequence-specific double-stranded complexes with RNA they are suitable use in antisense therapy. In one application, translation blocking, a morpholino oligomer binds to messenger RNA produced by a known disease-causing gene to prevent it from being translated into protein. Morpholinos can also work as splice-switching oligos, targeting pre-mRNA to alter splicing and so causing changes in the structure of the mature mRNA (the mechanism of the approved drug eteplirsen). Morpholinos have been tested for a wide range of applications including prevention of cardiac restenosis after angioplasty, treatment of coronary artery bypass grafts, treatment of polycystic kidney disease, redirection of drug metabolism, treatment of some mutations causing Duchenne muscular dystrophy (DMD), and inhibition of infectious diseases. Their greatest clinical and commercial success thus far has been in the treatment of DMD. A new class of Morpholino oligos, the peptide-linked Morpholinos or PPMO, are linked to an arginine-rich cell-penetrating peptide to enhance their delivery into cells and have entered clinical trials.

The Morpholino drug eteplirsen, targeting exon 51 of the dystrophin mRNA, was approved as a human therapeutic by the FDA in 2016 and antisense oligonucleotides for Morpholinos targeting other exons are also subsequently approved. Morpholinos have been used in preclinical studies to inhibit replication of a broad range of viruses, including influenza, West Nile virus, SARS, hepatitis C, dengue fever, Ebola and Calicivirus, all of which are single stranded RNA viruses. They are in advanced development for prevention and treatment of Ebola and Marburg viruses. In March 2013, the Company announced positive results from a non-human primate study of AVI-7288, the drug candidate for treatment of Marburg virus infection. The results showed that intramuscular administration of AVI-7288 resulted in survival rates up to 100 percent in monkeys exposed to this fatal virus. These results are similar to those in previous studies when the drug was given by intravenous injection.

In December 2019, golodirsen (Vyondys 53) received US FDA approval for the treatment of cases that can benefit from skipping exon 53 of the dystrophin transcript. The other approved PMO developed by Sarepta is casimersen (AMONDYS45) which is indicated for the treatment of DMD in patients amendable by exon 45 skipping.

In addition to development of Morpholinos as therapeutics, AVI has conducted six human trials for colorectal and pancreatic cancers using their cancer vaccine AVICINE.

In 2019, Sarepta signed a licensing agreement with Roche for the development, and commercialization outside of USA, for SRP-9001. In June 2023, ELEVIDYS (Delandistrogene moxeparvovec) was approved by the FDA for use in 4-5-year-old boys with mutations in the DMD gene. The FDA granted accelerated approval to ELEVIDYS, which requires that the product be further studied to verify its clinical benefit.

In June 2024, the U.S. Food and Drug Administration expanded approval of delandistrogene moxeparvovec to include individuals with Duchenne muscular dystrophy with a confirmed mutation in the DMD gene who are at least 4 years of age. The FDA granted traditional approval for ambulatory patients and accelerated approval for non-ambulatory patients.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

sectorHealthcare industryBiotechnology employees835 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$2.20B
2016-12-31 → 2025-12-31
EPS$-7.13
2020-12-31 → 2025-12-31
Free Cash Flow$-307M
2016-12-31 → 2025-12-31
Net margin-6.9%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend SRPT 5Y avg Peer Median Verdict
P/E (TTM) -10.95Y avg ≈-0.3 ≈-0.3 · ·
P/S (TTM) 0.95Y avg ≈7.6 ≈7.6 31.2 Undervalued
P/B (MRQ) 1.25Y avg ≈11.7 ≈11.7 4.7 Undervalued
Price / FCF (TTM) 22.65Y avg ≈-21.1 ≈-21.1 · ·
Price / Cash Flow (TTM) 16.75Y avg ≈-27.8 ≈-27.8 · ·
Price / Tangible Book (MRQ) 1.25Y avg ≈11.9 ≈11.9 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -46.3%
Next Report Nov 02, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 4, 2026 $-0.05 $0.26 -119.0%
March 31, 2026 $2.88 $1.01 184.7%
Dec. 31, 2025 $-3.93 $-1.26 -213.0%
Sept. 30, 2025 $-0.01 $-0.83 98.8%
June 30, 2025 $1.89 $0.77 146.8%
March 31, 2025 $-4.60 $-0.97 -376.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 17
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $2.20B$1.90B$1.24B$933M$702M$540M$381M$301M$155M$5M$1M$10M
Cost of Revenue $26M········$130.0K··
R&D Expense ·······$402M$167M$188M$146M$94M
SG&A Expense $492M$558M$482M$451M$283M$318M$285M$208M$123M$84M$75M$49M
Operating Expenses $2.90B$1.68B$1.51B$1.47B$1.16B$1.10B$1.09B$645M$326M$272M$221M$144M
Operating Income $-700M$218M$-268M$-536M$-460M$-564M$-706M$-344M$-172M$-267M$-220M$-134M
Interest Expense $-38M$-18M$-22M$-53M$64M$60M$31M$34M$6M$2M$1M·
Interest Income $31M$31M$36M$16M$354.0K$3M$7M$7M$2M$507.0K$890.0K·
Other Non-op $-19M$43M$33M$-28M$-61M$11M$-236.0K$-656.0K$601.0K$930.0K$154.0K$779.0K
Pretax Income $-702M$261M$-520M$-690M$-419M$-553M$-714M$-363M$-49M$-267M$-220M·
Income Tax $11M$26M$16M$14M$-168.0K$1M$1M$-692.0K$2M···
Net Income $-713M$235M$-536M$-703M$-419M$-554M$-715M$-362M$-51M$-267M$-220M$-136M
EPS (Basic) $-7.13$2.47$-5.80$-8.03$-5.15$-7.11······
EPS (Diluted) $-7.13$2.34$-5.80$-8.03$-5.15$-7.11······
Shares (Basic) 100,120,00095,075,00092,398,00087,559,00081,262,00077,956,00073,615,00066,250,00058,818,00048,697,00042,290,00040,026,000
Shares (Diluted) 100,120,000107,875,00092,398,00087,559,00081,262,00077,956,00073,615,00066,250,00058,818,000···
EBITDA $-655M$256M$-223M$-494M$-422M$-537M$-675M$-331M$-164M$-261M·$-130M
Balance Sheet 30
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $801M$1.10B$428M$967M$2.12B$1.50B$835M$371M$600M$122M$80M$74M
Short-term Investments $138M$252M$1.25B$1.02B$0$436M$290M$803M$479M$195M$112M$137M
Receivables $398M$602M$400M$215M$153M$101M$91M$49M$29M$5M$4M$2M
Inventory $915M$750M$323M$204M$186M$232M$171M$125M$84M$13M··
Prepaid Expense ·········$1M$3M$3M
Other Current Assets $172M$90M$78M$150M$149M$213M$82M$78M$37M$27M$17M$35M
Current Assets $2.54B$3.07B$2.58B$2.56B$2.60B$2.49B$1.47B$1.43B$1.23B$373M$225M$248M
PP&E (Net) $345M$340M$227M$180M$191M$190M$130M$97M$43M$38M$37M$39M
PP&E (Gross) $626M$574M$418M$329M$304M$266M$181M$125M$61M$68M$62M$58M
Accum. Depreciation $280M$234M$191M$149M$113M$76M$51M$28M$18M$30M$25M$20M
Intangibles $29M$27M$30M$8M$14M$14M$12M$12M$14M$8M$7M$6M
Other Non-current Assets $156M$80M$137M$163M$293M$204M$174M$107M$22M$4M$4M$2M
Total Assets $3.35B$3.96B$3.26B$3.13B$3.15B$2.98B$1.82B$1.64B$1.31B$424M$274M$295M
Accounts Payable $281M$214M$165M$96M$77M$111M$68M$34M$8M$30M$20M$12M
Accrued Liabilities $360M$374M$315M$419M$272M$194M$186M$134M$69M$31M$29M$17M
Short-term Debt ··········$2M$2M
Current Liabilities $1.10B$732M$654M$620M$453M$416M$265M$174M$88M$75M$62M$37M
Capital Leases $199M$192M$141M$58M$42M$80M$48M·····
Other Non-current Liabilities $2M$2M$3M$42.0K$11M$20M$5M$16M$6M$6M$6M$7M
Total Liabilities $2.21B$2.44B$2.41B$2.74B$2.22B$2.22B$1.00B$610M$519M$87M$83M$47M
Long-term Debt $829M$1.14B$1.24B$1.54B$564M··$421M$431M$18M$27M$7M
Total Debt ·$0$105M········$4M
Common Stock $11.0K$10.0K$9.0K$9.0K$9.0K$8.0K$8.0K$7.0K$6.0K$5.0K$5.0K$4.0K
Paid-in Capital ···········$927M
Retained Earnings $-4.88B$-4.21B$-4.45B$-3.91B$-3.21B$-2.85B$-2.29B$-1.58B$-1.22B$-1.17B$-899M$-679M
Treasury Stock $25M$0··········
AOCI $272.0K$-218.0K$918.0K$-2M$-20.0K$3.0K$50.0K$-99.0K$-379.0K$-120.0K$-111.0K$-95.0K
Stockholders' Equity $1.14B$1.53B$859M$385M$928M$762M$818M$1.03B$789M$337M$190M$248M
Liabilities + Equity $3.35B$3.96B$3.26B$3.13B$3.15B$2.98B$1.82B$1.64B$1.31B$424M$274M$295M
Shares Outstanding 104,964,22096,900,49693,731,83187,950,11787,126,97479,374,24775,184,86371,071,88764,791,67054,759,23445,629,52941,311,512
Cash Flow 19
Metric Trend 202520242023202220212020201920182017201620152014
D&A $45M$38M$44M$42M$38M$27M$24M$12M$8M$6M$5M$4M
Stock-based Comp $123M$184M$183M$233M$114M$108M$79M$50M$30M$30M$32M$20M
Deferred Tax $-363.0K$-249.0K$-165.0K$-612.0K$-309.0K$-245.0K$-376.0K$-240.0K····
Amort. of Intangibles $3M$2M$2M$714.0K$706.0K$662.0K$849.0K$865.0K$1M$29.0K··
Restructuring $42M$0$0·····$3M$4M·$14.0K
Other Non-cash $340M$-663M$-192M$104M$-176M$527M$150M$-89M$-220M$-14M·$-17M
Operating Cash Flow $-205M$-206M$-501M$-325M$-443M$107M$-456M$-389M$-232M$-246M$-149M$-129M
CapEx $102M$137M$76M$31M$38M$82M$60M$61M$12M$5M$3M$25M
Investing Cash Flow $70M$756M$-166M$-1.05B$495M$-122M$287M$-370M$-179M$-90M··
Debt Issued ···$0$0$291M$246M·$30M·$20M·
Net Debt Issued ···$0·$291M··$30M··$-94.0K
Stock Issued $20M$0$0$0$0$312M·$513M$354M$365M$120M$95M
Stock Repurchased $25M$0$0·········
Net Stock Activity $-5M··$0·$312M$365M$513M$354M$365M··
Financing Cash Flow $-168M$125M$125M$233M$562M$682M$643M$530M$888M$378M··
Net Change in Cash $-304M$675M$-542M$-1.14B$614M$668M$473M$-229M$477M$42M$7M$-183M
Taxes Paid $38M$23M$15M$2M$583.0K$3M$933.0K$2M$5M···
Free Cash Flow $-307M$-343M$-577M$-356M$-482M$25M$-516M$-450M$-244M$-251M·$-154M
Levered FCF $-269M$-326M$-600M$-410M$-545M$-35M$-547M$-483M$-250M···
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin -31.8%11.5%-21.5%-57.5%-65.5%-104.5%-185.3%-114.1%-111.0%-4920.3%··
Net Margin -32.5%12.4%-43.1%-75.4%-59.7%-102.6%-187.8%-120.2%-32.8%-4930.2%··
Pretax Margin -31.9%13.7%-41.8%-74.0%-59.7%-102.4%-187.5%-120.4%-31.5%···
EBITDA Margin -29.8%13.5%-18.0%-53.0%-60.1%-99.5%-177.2%-110.1%-105.8%-4816.8%··
ROA -19.5%6.5%-16.8%-22.4%-13.7%-23.1%-41.3%-24.5%-5.9%-76.6%·-46.3%
ROE -57.1%17.1%-66.0%-172.5%-59.9%-67.0%-78.9%-43.3%-9.0%-101.4%·-54.9%
ROIC -62.3%12.9%-28.6%-142.0%-49.5%-74.2%-86.4%-33.2%-22.7%···
Liquidity & Solvency 5
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 2.34.23.94.15.86.05.58.213.95.0·6.7
Quick Ratio 1.22.73.23.65.04.94.67.012.54.3·5.8
Debt / Equity ·0.00.1········0.0
LT Debt / Equity ···········0.0
Interest Coverage 18.3-11.9-12.2-10.1-7.2-9.4-23.0-10.2-29.7···
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.60.50.40.30.20.20.20.20.20.0··
Inventory Turnover 0.0········0.0··
Receivables Turnover 4.43.84.05.15.55.65.47.78.91.2··
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $10.87$15.77$9.17$4.38$10.65$9.60$10.88$14.52$12.18$6.15·$5.99
Revenue / Share $21.96$17.63$13.46$10.66$8.64$6.93$5.17·····
Cash Flow / Share $-2.05$-1.91$-5.42$-3.72$-5.45$1.38$-6.20·····
Cash / Share $7.63$11.38$4.57$10.99$24.28$18.93$11.11$5.22$9.26$2.24·$1.78
EPS (TTM) $-7.13$2.34$-5.80$-8.03$-5.15$-7.11$-3.37$-3.37$-0.80·$-6.37$-6.37
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 15.6%53.0%33.3%32.9%30.0%·······
Revenue CAGR 3Y 33.1%39.4%32.0%·········
Revenue CAGR 5Y 32.4%···········
Valuation (TTM) 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $2.20B$1.90B$1.24B$933M$702M$540M$381M$301M$155M$5M$1M$10M
Net Income TTM $-713M$235M$-536M$-703M$-419M$-554M$-715M$-362M$-51M$-267M$-220M$-136M
Market Cap $2.26B$11.78B$9.04B$11.40B$7.85B$13.53B$9.70B$7.76B$3.61B$1.50B·$598M
Enterprise Value ·$10.43B$7.47B········$391M
P/E -3.052.0-16.6-16.1-17.5-24.0-38.3-32.4-69.5·-6.1-2.3
P/S 1.06.27.312.211.225.125.525.823.3277.1·61.3
P/B 2.07.710.529.68.517.811.97.54.64.5·2.4
P / Tangible Book 2.07.910.930.28.618.1······
P / Cash Flow -11.0-57.3-18.0-35.0-17.7125.9-21.3-20.0-15.5-6.1·-4.7
P / FCF -7.3-34.4-15.7-32.0-16.3535.6-18.8-17.2-14.8-6.0·-3.9
EV / EBITDA ·40.8-33.4········-3.0
EV / FCF ·-30.4-12.9········-2.5
EV / Revenue ·5.56.0········40.1
Earnings Yield -33.1%1.9%-6.0%-6.2%-5.7%-4.2%-2.6%-3.1%-1.4%·-16.5%-44.0%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $2.20B $1.90B $1.24B $933M $702M
Operating Margin % -31.8% 11.5% -21.5% -57.5% -65.5%
Net Income $-713M $235M $-536M $-703M $-419M
Diluted EPS $-7.13 $2.34 $-5.80 $-8.03 $-5.15

Institutional owners (13F) 366 filers · $2.3B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 366
Value held $2.3B
New positions 50
Exited positions 60
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
50 (-9 vs prior Q) 60 (+14 vs prior Q) 101 (-10 vs prior Q) 125 (-17 vs prior Q) +3.1M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BlackRock, Inc. $341,339,398 18,994,958 14.85% Shares
VANGUARD GROUP INC $254,166,887 11,810,729 11.06% Shares
STATE STREET CORP $160,222,137 8,916,090 6.97% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $150,543,136 8,377,470 6.55% Shares
TWO SIGMA INVESTMENTS, LP $82,639,268 4,598,735 3.60% Shares
VANGUARD CAPITAL MANAGEMENT LLC $82,513,837 4,591,755 3.59% Shares
FIRST TRUST ADVISORS LP $78,456,086 4,365,951 3.41% Shares
AQR CAPITAL MANAGEMENT LLC $76,867,492 4,325,689 3.35% Shares
GEODE CAPITAL MANAGEMENT, LLC $49,818,796 2,771,758 2.17% Shares
Erste Asset Management GmbH $45,513,625 2,568,945 1.98% Shares
TWO SIGMA ADVISERS, LP $44,575,108 2,071,334 1.94% Shares
MARSHALL WACE, LLP $39,642,216 2,206,022 1.73% Shares
MORGAN STANLEY $39,581,468 2,202,641 1.72% Shares
Aberdeen Group plc $39,443,216 2,194,948 1.72% Shares
BANK OF AMERICA CORP /DE/ $36,946,051 2,055,985 1.61% Shares
GOLDMAN SACHS GROUP INC $36,703,734 2,042,501 1.60% Shares
UBS Group AG $29,190,737 1,624,415 1.27% Shares
FEDERATED HERMES, INC. $28,578,248 1,590,331 1.24% Shares
LMR Partners LLP $25,021,428 1,392,400 1.09% Put option
CITADEL ADVISORS LLC $23,727,588 1,320,400 1.03% Call option
NORTHERN TRUST CORP $21,756,855 1,210,732 0.95% Shares
MILLENNIUM MANAGEMENT LLC $21,446,620 1,193,468 0.93% Shares
CITIGROUP INC $20,755,457 1,155,006 0.90% Shares
RENAISSANCE TECHNOLOGIES LLC $20,151,163 1,121,378 0.88% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $17,616,368 980,321 0.77% Shares
Connor, Clark & Lunn Investment Management Ltd. $17,493,669 973,493 0.76% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $16,823,514 936,200 0.73% Put option
Invesco Ltd. $16,233,721 903,379 0.71% Shares
Legal & General Group Plc $15,770,961 877,627 0.69% Shares
683 Capital Management, LLC $14,061,525 782,500 0.61% Shares
Bank of New York Mellon Corp $13,911,725 774,164 0.61% Shares
ADAR1 Capital Management, LLC $13,129,763 730,649 0.57% Shares
DIMENSIONAL FUND ADVISORS LP $12,640,823 703,629 0.55% Shares
VANGUARD FIDUCIARY TRUST CO $12,548,685 698,313 0.55% Shares
BNP PARIBAS FINANCIAL MARKETS $12,240,212 681,147 0.53% Shares
Jump Financial, LLC $12,209,627 679,445 0.53% Shares
Voleon Capital Management LP $12,116,183 674,245 0.53% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $12,059,667 671,100 0.52% Call option
Qube Research & Technologies Ltd $10,958,034 609,796 0.48% Shares
MACKENZIE FINANCIAL CORP $10,774,381 599,576 0.47% Shares
HOTCHKIS & WILEY CAPITAL MANAGEMENT LLC $10,165,988 565,720 0.44% Shares
JPMORGAN CHASE & CO $9,345,699 544,392 0.41% Shares
Point72 Asset Management, L.P. $9,181,017 510,908 0.40% Shares
PRINCIPAL FINANCIAL GROUP INC $9,175,572 510,605 0.40% Shares
Casdin Capital, LLC $8,445,900 470,000 0.37% Shares
Assenagon Asset Management S.A. $8,165,119 454,375 0.36% Shares
PANAGORA ASSET MANAGEMENT INC $8,120,068 451,868 0.35% Shares
Hudson Bay Capital Management LP $8,086,500 450,000 0.35% Shares
Man Group plc $7,154,647 398,144 0.31% Shares
PRUDENTIAL FINANCIAL INC $7,083,235 394,170 0.31% Shares

Show all 366 institutional owners →

Activists & 5%+ owners 6 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Richard J. Barry (2) May 5, 2015 · Initial filing · SEC
George W. Haywood, Cheryl Haywood, Rockall Emerging Markets Master Fund Ltd., Meldrum Asset Management, LLC, Con Egan, Conor O’Driscoll ×2 filings April 22, 2010 · Initial filing · SEC
Eastbourne Capital Management, L.L.C., Richard Jon Barry, Black Bear Offshore Master Fund, L.P., Black Bear Fund I, L.P., Black Bear Fund II, L.L.C. ×4 filings March 8, 2010 · Initial filing · SEC
Medtronic, Inc., Medtronic International, Ltd. Feb. 14, 2005 · Initial filing Passive investment SEC
Undisclosed reporting person Jan. 8, 2002 · Initial filing Passive investment SEC
Undisclosed reporting person June 29, 2001 · Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 65 insiders · 29 officers · 18 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Michael Severino Chief Executive Officer July 28, 2026 A 756,104 0 0 $0
Douglas S Ingram Chief Executive Officer Dec. 7, 2025 A 929,391 0 0 $0
David J Boyle II CEO Aug. 27, 2010 P 70,282 0 0 $0
Leslie Hudson Former CEO July 30, 2010 M 384,559 0 0 $0
Denis R Burger Chief Executive Officer April 3, 2007 A 151,717 0 0 $0
Ryan Ho-Yan Wong Chief Financial Officer Sept. 4, 2026 F 121,792 0 0 $0
Sandesh Mahatme EVP, CFO & CBO July 8, 2020 M 20,260 0 0 $0
Louise Rodino-Klapac President, R&D and Tech Ops Sept. 4, 2026 F 203,900 0 0 $0
Ian Michael Estepan Chief Operating Officer Sept. 4, 2026 F 177,184 0 1 $-294,202
Cristin Rothfuss EVP, General Counsel Sept. 4, 2026 F 115,519 0 0 $0
Bilal Arif Chief Tech Ops Officer Aug. 5, 2025 A 32,500 0 0 $0
Dallan Murray Chief Customer Officer March 10, 2025 A 38,202 0 0 $0
Ryan Edward Brown EVP, General Counsel June 25, 2024 M 17,129 0 0 $0
William Ciambrone EVP March 7, 2022 A 22,099 0 0 $0
Joseph Bratica Principal Financial Officer Dec. 11, 2020 M 8,140 0 0 $0
David T Howton EVP, General Counsel June 22, 2020 M 31,871 0 0 $0
Alexander Cumbo EVP, Chief Commercial Officer Feb. 28, 2020 A 8,567 0 0 $0
Shamim Ruff SVP, Chief Regulatory Affairs May 22, 2018 M 31,936 0 0 $0
Guriqbal S. Basi SVP, Chief Scientific Officer March 5, 2018 A · 0 0 $0
Arthur M Krieg SVP, Chief Scientific Officer Jan. 13, 2014 A · 0 0 $0
Michael A Jacobsen VP of Finance and PAO Aug. 23, 2012 A 7,500 0 0 $0
Bracha Ephrat Toshav Sr VP & General Counsel Aug. 31, 2011 A · 0 0 $0
Melinda G Mile Controller and PAO Aug. 31, 2011 A · 0 0 $0
Peter S Linsley SVP & Chief Scientific Officer May 16, 2011 A · 0 0 $0
Graham Johnson Sr VP Preclinical Dev & Rsrch Aug. 23, 2010 A · 0 0 $0
Paul Medeiros SVP Business Development Aug. 23, 2010 A · 0 0 $0
Stephen B Shrewsbury SVP/Regulatory Affairs Aug. 23, 2010 A 60,000 0 0 $0
Patrick L Iversen Sr VP of Research & Devlopment Aug. 23, 2010 A 86,303 0 0 $0
Dwight D Weller Sr. VP Chemistry & Mfg. Aug. 23, 2010 A 314,741 0 0 $0
Michael Andrew Chambers Director June 4, 2026 A 27,535 0 0 $0
Stephen Mayo Director June 4, 2026 A 18,640 0 1 $-123,208
Kathryn Jean Boor Director June 4, 2026 A 25,138 0 0 $0
Claude Nicaise Director June 4, 2026 A 48,407 0 0 $0
Richard Barry Director June 4, 2026 A 2,983,542 0 0 $0
Hans Lennart Rudolf Wigzell Director June 4, 2026 A 42,098 0 0 $0
Deirdre P Connelly Director June 4, 2026 A 22,100 0 0 $0
Kathleen M Behrens Director June 4, 2026 A 214,357 0 0 $0
Mary Ann Gray Director March 7, 2022 A 12,356 0 0 $0
John C Martin Director March 3, 2021 A 7,913 0 0 $0
Michael W Bonney Director Feb. 28, 2020 A 9,126 0 0 $0
Edward M. Kaye MD Director Aug. 3, 2017 M 71,229 0 0 $0
Jean-Paul Kress Director March 10, 2017 A 2,000 0 0 $0
Ben Gil Price Director March 14, 2016 P 42,830 0 0 $0
William Alden Goolsbee Director Feb. 29, 2016 A 8,166 0 0 $0
EASTBOURNE CAPITAL MANAGEMENT LLC/CA 10% owner March 4, 2010 S 5,659,211 0 0 $0
MEDTRONIC INC 10% owner May 25, 2004 S 0 0 0 $0
Gilmore Neil O'Neill · March 3, 2021 A 28,546 0 0 $0
Catherine Stehman-Breen · April 3, 2017 A · 0 0 $0
Jayant Aphale · Sept. 19, 2016 M 11,490 0 0 $0
Nishan Garabedian Christopher · Feb. 27, 2015 A 29,552 0 0 $0
Anthony R Chase · Feb. 27, 2015 A 67,194 0 0 $0
John Hodgman · Feb. 27, 2015 A 6,333 0 0 $0
Anthony Martignetti · June 4, 2013 A · 0 0 $0
Ryszard Kole · Feb. 9, 2010 A 1,862,926 0 0 $0
George Weaver Haywood · Aug. 25, 2009 P 8,213,717 0 0 $0
Michael D Casey · May 19, 2009 A 5,000 0 0 $0
FORREST K MICHAEL · May 19, 2009 A 15,000 0 0 $0
Christopher S Henney · March 31, 2009 A · 0 0 $0
John W Fara PHD · May 20, 2008 A · 0 0 $0
Peter D Ohanley · Feb. 28, 2008 A · 0 0 $0
Mark Miles Webber · Feb. 28, 2008 A · 0 0 $0
Alan P Timmins · Feb. 2, 2008 J · 0 0 $0
James B Hicks · May 22, 2007 A 6,000 0 0 $0
Jack L Bowman · May 22, 2007 A 5,000 0 0 $0
Joseph B Horn · March 22, 2006 A · 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 56 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PBE · Invesco Exchange-Traded Fund Trust 2.63% 620,211 SH Oct. 2, 2026 Daily
IBRN · iShares Trust 2.18% 7,938 SH Sept. 11, 2026 Daily
BBP · ETFis Series Trust I 1.34% 88,646 NS July 31, 2026 N-PORT
PSCH · Invesco Exchange-Traded Fund Trust … 1.02% 100,590 SH Oct. 2, 2026 Daily
HAPS · Harbor ETF Trust 0.81% 92,720 NS July 31, 2026 N-PORT
XSHQ · Invesco Exchange-Traded Fund Trust … 0.50% 82,108 SH Oct. 2, 2026 Daily
LABU · Direxion Shares ETF Trust 0.45% 151,157 NS July 31, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.44% 5,675 SH Oct. 2, 2026 Daily
IBB · iShares Trust 0.15% 772,730 SH Sept. 11, 2026 Daily
SMDX · Tidal Trust III 0.15% 13,054 NS July 31, 2026 N-PORT
VFVA · VANGUARD WELLINGTON FUND 0.14% 64,607 SH Aug. 19, 2026 Daily
VIOG · VANGUARD ADMIRAL FUNDS 0.13% 76,657 SH Aug. 19, 2026 Daily
ESSC · Strategy Shares 0.13% 3,094 NS July 31, 2026 N-PORT
PWS · Pacer Funds Trust 0.13% 2,065 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.12% 7,460 SH Oct. 2, 2026 Daily
QVMS · Invesco Exchange-Traded Fund Trust … 0.11% 15,261 SH Oct. 2, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.11% 84,228 SH Aug. 19, 2026 Daily
FYC · First Trust Exchange-Traded AlphaDE… 0.11% 95,830 NS July 31, 2026 N-PORT
RWJ · Invesco Exchange-Traded Fund Trust … 0.10% 113,747 SH Oct. 2, 2026 Daily
VIOO · VANGUARD ADMIRAL FUNDS 0.10% 369,221 SH Aug. 19, 2026 Daily
VIOV · VANGUARD ADMIRAL FUNDS 0.08% 87,370 SH Aug. 19, 2026 Daily
IWM · iShares Trust 0.07% 2,658,934 SH Sept. 11, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.06% 598,819 SH Aug. 19, 2026 Daily
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.06% 27,534 NS July 31, 2026 N-PORT
VBK · VANGUARD INDEX FUNDS 0.05% 1,332,977 SH Aug. 19, 2026 Daily
RSSL · Global X Funds 0.05% 49,826 NS July 31, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.03% 299,980 SH Aug. 19, 2026 Daily
FAD · First Trust Exchange-Traded AlphaDE… 0.02% 8,682 NS July 31, 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0.02% 46,891 NS July 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.02% 1,210,549 SH Aug. 19, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.02% 2,292,990 SH Aug. 19, 2026 Daily
WSML · iShares Trust 0.02% 6,093 SH Sept. 11, 2026 Daily
DXUV · Dimensional ETF Trust 0.02% 6,769 NS July 31, 2026 N-PORT
PRF · Invesco Exchange-Traded Fund Trust 0.01% 68,063 SH Oct. 2, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 7,772 SH Aug. 19, 2026 Daily
IWO · iShares Trust 0.01% 67,657 SH Sept. 11, 2026 Daily
TILT · FlexShares Trust 0.01% 13,904 NS July 31, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.01% 83,934 NS July 31, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.01% 11,994 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 8,729 NS July 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 141,450 SH Sept. 11, 2026 Daily
DFUS · Dimensional ETF Trust 0.00% 37,436 NS July 31, 2026 N-PORT
IWV · iShares Trust 0.00% 25,570 SH Sept. 11, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 22,144 NS July 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 65,871 NS July 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.00% 3,187,072 SH Aug. 19, 2026 Daily
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.00% 80,332 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 8,458 SH Aug. 19, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.00% 23,052 SH Aug. 19, 2026 Daily
IJR · iShares Trust · 6,444,975 SH Sept. 10, 2026 Daily
IJT · iShares Trust · 613,122 SH Sept. 9, 2026 Daily
IJS · iShares Trust · 369,121 SH Sept. 8, 2026 Daily
IWN · iShares Trust · 910,181 SH Sept. 11, 2026 Daily
XJR · iShares Trust · 14,552 SH Aug. 31, 2026 Daily
ISCB · iShares Trust · 4,621 SH Sept. 11, 2026 Daily
ISCV · iShares Trust · 22,361 SH Sept. 11, 2026 Daily

SRPT Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 33 analysts HOLD
Median target $20.00 +14.3%
8 24.2% Strong Buy
6 18.2% Buy
13 39.4% Hold
5 15.2% Sell
1 3.0% Strong Sell

12-Month Price Target

22 analysts · 2026-10-03

Mean target $21.73 +24.2%

Now Current price $17.50
Low$5.00 Mean$21.73 High$38.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
SRPT $2.26B -3.0 15.6% -32.5% -57.1% ·
BHVN $1.50B -1.6 · · -310.8% ·
PVLA $1.30B -28.2 65.3% -1610.6% -110.1% ·
ABSI $529M -4.2 -38.2% -4113.7% -63.5% ·
AGIO $1.59B -3.8 48.0% -764.0% -32.2% ·
VIR $841M -1.9 -7.6% -638.9% -51.1% ·
GENB · · · · · ·
NVAX $1.09B 2.6 64.7% 39.2% -977.1% ·
NTLA $1.05B -2.4 16.9% -609.8% -59.5% ·
STOK $1.87B -264.5 404.5% -3.7% -2.0% ·

Latest News Recent headlines mentioning this company

23

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 5, 2026