FHTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $2.02
Market Cap (MRQ) $119M
P/E (TTM) -2.0
EPS (TTM) $-0.99
Revenue (TTM) $37M
ROE (TTM) 81.9%
52W Range $2–$8

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10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$31M
2020-12-31 → 2025-12-31
EPS$-1.18
2020-12-31 → 2025-12-31
Free Cash Flow$-86M
2021-12-31 → 2025-12-31
Net margin-175.8%
2021-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend FHTX 5Y avg Peer Median Verdict
P/E (TTM) -2.05Y avg ≈-4.2 ≈-4.2 · ·
P/S (TTM) 3.25Y avg ≈10.8 ≈10.8 48.5 Undervalued
P/B (MRQ) -1.55Y avg ≈592.3 ≈592.3 · ·
Price / FCF (TTM) -1.45Y avg ≈-1.8 ≈-1.8 · ·
Price / Cash Flow (TTM) -1.45Y avg ≈-1.8 ≈-1.8 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 16.3%
Next Report Nov 03, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 11, 2026 $-0.10 $-0.26 61.7%
March 31, 2026 May 12, 2026 $-0.29 $-0.31 6.8%
Dec. 31, 2025 $-0.34 $-0.25 -34.8%
Sept. 30, 2025 $-0.25 $-0.34 26.4%
June 30, 2025 $-0.28 $-0.37 23.4%
March 31, 2025 $-0.30 $-0.35 14.0%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

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Income Statement 15
Metric Trend 202520242023202220212020
Revenue $31M$23M$34M$19M$1M$430.0K
R&D Expense $85M$95M$110M$106M$80M$58M
SG&A Expense $28M$28M$32M$31M$22M$11M
Operating Expenses $117M$125M$142M$136M$102M$69M
Operating Income $-86M$-103M$-108M$-117M$-101M$-69M
Interest Expense ····$2M$979.0K
Other Non-op $12M$16M$14M$8M$2M$-269.0K
Pretax Income ·$-87M$-94M$-109M··
Income Tax $0$0$4M$0·$0
Net Income $-74M$-87M$-98M$-109M$-101M$-69M
EPS (Basic) $-1.18$-1.58$-2.34$-2.62$-2.73$-6.23
EPS (Diluted) $-1.18$-1.58$-2.34$-2.62$-2.73$-6.23
Shares (Basic) 62,980,95954,899,43241,974,48441,591,43337,171,14711,046,802
Shares (Diluted) 62,980,95954,899,43241,974,48441,591,43337,171,14711,046,802
EBITDA $-83M$-100M$-104M$-114M$-98M·
Balance Sheet 23
Metric Trend 202520242023202220212020
Cash & Equivalents $81M$55M$80M$52M$101M$93M
Prepaid Expense $3M$6M$6M$6M$5M$5M
Current Assets $163M$250M$240M$351M$460M$191M
PP&E (Net) ·····$20M
PP&E (Gross) ·····$22M
Accum. Depreciation ·····$2M
Other Non-current Assets $4.0K$68.0K$1M$2M$2M$842.0K
Total Assets $198M$284M$286M$405M$520M$256M
Accounts Payable $4M$4M$6M$5M$4M$4M
Accrued Liabilities $11M$9M$9M$11M$10M$9M
Current Liabilities $60M$67M$58M$55M$49M$19M
Capital Leases $40M$28M$37M$46M$51M$58M
Other Non-current Liabilities $556.0K$0$0$29.0K$143.0K$0
Total Liabilities $307M$330M$363M$405M$423M$109M
Long-term Debt ·····$20M
Total Debt ····$0·
Common Stock $6.0K$6.0K$4.0K$4.0K$4.0K$4.0K
Paid-in Capital $524M$513M$395M$377M$361M$309M
Retained Earnings $-632M$-558M$-472M$-373M$-264M$-163M
AOCI $24.0K$135.0K$-826.0K$-4M$-10.0K$-7.0K
Stockholders' Equity $-108M$-46M$-77M$112.0K$97M$146M
Liabilities + Equity $198M$284M$286M$405M$520M$256M
Shares Outstanding 56,657,32955,594,13142,282,04041,803,43641,299,72036,790,946
Cash Flow 11
Metric Trend 202520242023202220212020
D&A $3M$3M$3M$3M$3M$1M
Stock-based Comp $10M$12M$16M$14M$8M$3M
Other Non-cash $-26M$-29M$-39M$285M$39M·
Operating Cash Flow $-86M$-100M$-118M$194M$-50M$-31M
CapEx $50.0K$906.0K$1M$1M$3M$16M
Investing Cash Flow $112M$-30M$144M$-244M$36M$-109M
Stock Issued ·$103M$0···
Net Stock Activity ·$103M····
Financing Cash Flow $1M$105M$2M$2M$22M$217M
Taxes Paid $9.0K$860.0K$4M···
Free Cash Flow $-86M$-101M$-119M$192M$-54M·
Profitability 7
Metric Trend 202520242023202220212020
Operating Margin -279.5%-454.3%-315.9%-609.2%-7637.1%·
Net Margin -240.3%-383.2%-288.2%-566.3%-7681.6%·
Pretax Margin ·-383.2%-275.8%···
EBITDA Margin -268.7%-440.5%-305.8%-591.9%-7392.5%·
ROA -30.8%-30.4%-28.5%-23.5%··
ROE 80.2%234.7%146.3%-891.2%··
ROIC ·225.5%146.1%···
Liquidity & Solvency 3
Metric Trend 202520242023202220212020
Current Ratio 2.73.74.16.4··
Quick Ratio 1.40.81.40.9··
Interest Coverage ····-52.9·
Efficiency 1
Metric Trend 202520242023202220212020
Asset Turnover 0.10.10.10.0··
Per Share 5
Metric Trend 202520242023202220212020
Book Value / Share $-1.92$-0.82$-1.83$0.00··
Revenue / Share $0.49$0.41$0.81$0.46$0.04·
Cash Flow / Share $-1.37$-1.83$-2.81$4.66$-1.35·
Cash / Share $1.43$1.00$1.90$1.25··
EPS (TTM) $-1.18$-1.58$-2.34$-2.62$-2.73$-6.23
Growth Rates 3
Metric Trend 202520242023202220212020
Revenue YoY 36.8%-33.8%77.6%1357.8%206.7%·
Revenue CAGR 3Y 17.1%157.8%329.9%···
Revenue CAGR 5Y 135.1%·····
Valuation (TTM) 10
Metric Trend 202520242023202220212020
Revenue TTM $31M$23M$34M$19M$1M$430.0K
Net Income TTM $-74M$-87M$-98M$-109M$-101M$-69M
Market Cap $306M$262M$273M$267M··
P/E -4.6-3.0-2.8-2.4-8.4-3.3
P/S 9.911.68.013.9··
P/B -2.8-5.8-3.52381.3··
P / Tangible Book ···2381.39.85.1
P / Cash Flow -3.6-2.6-2.31.4··
P / FCF -3.6-2.6-2.31.4··
Earnings Yield -21.9%-33.5%-36.3%-41.1%-11.9%-30.7%

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $31M $23M $34M $19M $1M
Operating Margin % -279.5% -454.3% -315.9% -609.2% -7637.1%
Net Income $-74M $-87M $-98M $-109M $-101M
Diluted EPS $-1.18 $-1.58 $-2.34 $-2.62 $-2.73

Institutional owners (13F) 106 filers · $229.3M total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 106
Value held $229.3M
New positions 15
Exited positions 14
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
15 (-7 vs prior Q) 14 (+5 vs prior Q) 38 (-1 vs prior Q) 26 (+6 vs prior Q) +940K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Flagship Pioneering, LLC $61,849,706 12,674,120 26.98% Shares
BVF INC/IL $28,508,960 5,842,000 12.44% Shares
FMR LLC $27,845,075 5,705,958 12.15% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $21,444,511 4,394,367 9.35% Shares
BlackRock, Inc. $12,818,939 2,626,832 5.59% Shares
RAYMOND JAMES FINANCIAL INC $12,151,093 2,489,978 5.30% Shares
VANGUARD GROUP INC $10,416,557 1,928,992 4.54% Shares
Euclidean Capital LLC $7,679,954 1,573,761 3.35% Shares
VANGUARD CAPITAL MANAGEMENT LLC $7,293,702 1,494,611 3.18% Shares
GEODE CAPITAL MANAGEMENT, LLC $4,446,091 910,866 1.94% Shares
Siren, L.L.C. $3,517,114 720,720 1.53% Shares
STATE STREET CORP $3,403,649 697,469 1.48% Shares
AMERIPRISE FINANCIAL INC $2,726,383 558,685 1.19% Shares
RENAISSANCE TECHNOLOGIES LLC $1,844,328 377,936 0.80% Shares
Candriam S.C.A. $1,529,700 313,765 0.67% Shares
NORTHERN TRUST CORP $1,511,703 309,775 0.66% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $1,490,518 305,434 0.65% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $1,485,628 304,432 0.65% Shares
Birchview Capital, LP $1,375,853 281,937 0.60% Shares
VANGUARD FIDUCIARY TRUST CO $1,290,379 264,422 0.56% Shares
Qube Research & Technologies Ltd $992,084 203,296 0.43% Shares
Woodline Partners LP $986,468 202,145 0.43% Shares
B Group, Inc. $976,000 200,000 0.43% Shares
PANAGORA ASSET MANAGEMENT INC $855,981 175,406 0.37% Shares
GOLDMAN SACHS GROUP INC $801,569 164,256 0.35% Shares
CITADEL ADVISORS LLC $775,051 158,822 0.34% Shares
Squarepoint Ops LLC $636,088 130,346 0.28% Shares
DAFNA Capital Management LLC $545,872 111,859 0.24% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $535,731 109,781 0.23% Shares
SCS Capital Management LLC $522,062 106,980 0.23% Shares
MORGAN STANLEY $449,429 92,096 0.20% Shares
Palumbo Wealth Management LLC $447,687 91,739 0.20% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $437,248 89,600 0.19% Shares
Bank of New York Mellon Corp $387,253 79,355 0.17% Shares
Invesco Ltd. $381,298 78,135 0.17% Shares
DIADEMA PARTNERS LP $326,511 66,908 0.14% Shares
AQR CAPITAL MANAGEMENT LLC $323,247 66,239 0.14% Shares
Nuveen, LLC $317,390 65,039 0.14% Shares
Lynx1 Capital Management LP $300,549 61,588 0.13% Shares
STATE OF WISCONSIN INVESTMENT BOARD $283,499 58,094 0.12% Shares
MILLENNIUM MANAGEMENT LLC $261,124 53,509 0.11% Shares
Verdad Advisers, LP $259,767 53,231 0.11% Shares
Persistent Asset Partners Ltd $228,735 46,872 0.10% Shares
SILVERARC CAPITAL MANAGEMENT, LLC $224,358 45,975 0.10% Shares
RHUMBLINE ADVISERS $193,152 39,582 0.08% Shares
DEUTSCHE BANK AG\ $178,301 36,537 0.08% Shares
Jump Financial, LLC $177,549 36,383 0.08% Shares
WELLS FARGO & COMPANY/MN $172,268 35,301 0.08% Shares
ALLIANCEBERNSTEIN L.P. $142,253 29,760 0.06% Shares
BANK OF AMERICA CORP /DE/ $127,383 26,103 0.06% Shares

Show all 106 institutional owners →

Activists & 5%+ owners 2 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Flagship Ventures Fund V, L.P., Flagship Ventures Fund V General Partner LLC, Flagship Ventures Opportunities Fund I, L.P., Flagship Ventures Opportunities Fund I General Partner LLC, Flagship Pioneering Special Opportunities Fund II, L.P., Flagship Pioneering Special Opportunities Fund II General Partner LLC, Flagship Pioneering Fund VII, L.P., Flagship Pioneering Fund VII General Partner LLC, Flagship Pioneering, LLC, Noubar Afeyan Jan. 13, 2026 27.20% Amendment · SEC
Flagship Ventures Fund V, L.P. (2), Flagship Ventures Fund V General Partner LLC (2), Flagship Ventures Opportunities Fund I, L.P. (2), Flagship Ventures Opportunities Fund I General Partner LLC (2), Flagship Pioneering Special Opportunities Fund II, L.P. (2), Flagship Pioneering Special Opportunities Fund II General Partner LLC (2), Flagship Pioneering Fund VII, L.P. (2), Flagship Pioneering Fund VII General Partner LLC (2), Flagship Pioneering, Inc. (2), Noubar Afeyan (2) ×2 filings May 24, 2024 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 23 insiders · 11 officers · 12 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Adrian Gottschalk Chief Executive Officer April 10, 2026 G 270,912 0 0 $0
Kristian Humer Chief Financial Officer Jan. 22, 2025 A · 0 0 $0
Allan Reine Chief Financial Officer Jan. 26, 2023 A 53,784 0 0 $0
Anna Rivkin Chief Business Officer Jan. 30, 2026 A · 0 0 $0
Carlos Costa Chief People Officer Jan. 30, 2026 A 0 0 0 $0
Michael Lacascia Chief Legal Officer Jan. 30, 2026 A · 0 0 $0
Steven F. Bellon Chief Scientific Officer Jan. 30, 2026 A 101,957 0 0 $0
Alfonso Quintas Cardama Chief Medical Officer Jan. 30, 2026 A · 0 0 $0
Fanny Cavalie Chief Strategy/Bus Ops Officer March 11, 2024 S 75,992 0 0 $0
Samuel Agresta Chief Medical Officer Aug. 16, 2023 M 0 0 0 $0
Carl Decicco Chief Scientific Officer Dec. 9, 2021 M 362,707 0 0 $0
Neil Gallagher Director June 24, 2026 A · 0 0 $0
Stuart Duty Director June 24, 2026 A · 0 0 $0
Michael Mendelsohn Director June 24, 2026 A · 0 0 $0
Scott Biller Director June 24, 2026 A · 0 0 $0
Douglas G. Cole Director June 24, 2026 A · 0 0 $0
Thomas J. Lynch Jr. Director June 24, 2026 A · 0 0 $0
Ian F Smith Director June 24, 2026 A · 0 0 $0
Simba Gill Director June 24, 2026 A 34,061 0 0 $0
Lynne B Parshall Director June 24, 2026 A · 0 0 $0
Adam Koppel Director June 26, 2024 A · 0 0 $0
Cigall Kadoch Director June 21, 2022 A · 0 0 $0
Ryan D Maynard · Feb. 23, 2026 A · 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 13 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
OMFS · Invesco Exchange-Traded Self-Indexe… 0.07% 49,159 SH Oct. 1, 2026 Daily
IWC · iShares Trust 0.04% 124,539 SH Sept. 11, 2026 Daily
IBBQ · Invesco Exchange-Traded Fund Trust … 0.01% 4,209 SH Oct. 1, 2026 Daily
IWO · iShares Trust 0.01% 342,513 SH Sept. 11, 2026 Daily
IBB · iShares Trust 0.01% 236,414 SH Sept. 11, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.01% 209,037 SH Aug. 19, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.01% 39,520 SH Aug. 19, 2026 Daily
RSSL · Global X Funds 0.01% 17,433 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.01% 880,194 SH Sept. 11, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.00% 10,850 SH Sept. 29, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.00% 428,310 SH Aug. 19, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 1,027,071 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 2,231 SH Aug. 19, 2026 Daily

FHTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 16 analysts BUY
Median target $12.00 +494.1%
7 43.8% Strong Buy
8 50.0% Buy
1 6.2% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

9 analysts · 2026-09-20

Mean target $11.44 +466.6%

← Below all targets Current price $2.02
Low$9.00 Mean$11.44 High$14.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
FHTX $306M -4.6 36.8% -240.3% 80.2% ·
ABOS $128M -1.1 · · -129.4% ·
HUMA · · · · · ·
KRRO $75M -0.6 181.5% -1834.5% -140.8% ·
OTLK $57M -0.6 · -4416.2% 193.1% 4.0%
PMVP $67M -0.8 -40.5% -1226.8% -63.4% ·
RNA $10.91B -14.5 72.1% -3650.4% -47.5% ·
CRBU $151M -1.0 11.7% -1327.4% -102.8% ·
SPRB $120M -1.7 -51.3% · -139.9% ·
TNYA $154M -1.2 · · -81.2% ·

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Source: SEC 10-Q filed Aug 6, 2026