WVE Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $3.78
Market Cap (MRQ) $731M
P/E -14.0
EPS $-1.21
Revenue $43M
52W Range $4–$21

WVE Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

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About Wave Life Sciences Ltd. - Ordinary Shares Company overview from Wikipedia

05 · wikidata
sectorHealthcare industryPharmaceuticals employees317 countrySG

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$43M
2016-12-31 → 2025-12-31
EPS$-1.21
2021-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend WVE 5Y avg Peer Median Verdict
P/E -14.05Y avg ≈-9.2 ≈-9.2 · ·
P/B (MRQ) 1.6 · · ·
Price / FCF (TTM) -3.8 · · ·
Price / Cash Flow (TTM) -3.8 · · ·
Price / Tangible Book 6.25Y avg ≈9.0 ≈9.0 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

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Avg Surprise 3.3%
Next Report Nov 09, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Jul 28, 2026 $-0.34 $-0.31 -8.9%
March 31, 2026 May 7, 2026 $-0.13 $-0.33 60.7%
Dec. 31, 2025 $-0.30 $-0.27 -10.0%
Sept. 30, 2025 $-0.32 $-0.30 -6.2%
June 30, 2025 $-0.31 $-0.29 -5.6%
March 31, 2025 $-0.29 $-0.26 -10.1%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

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Income Statement 13
Metric Trend 20252024202320222021202020192018201720162015
Revenue $43M$108M$113M$4M$41M$20M$16M$14M$4M$1M$152.0K
R&D Expense $183M$160M$130M$116M$122M$131M$175M$134M$79M$41M$9M
SG&A Expense $75M$59M$51M$51M$46M$43M$49M$40M$27M$16M$10M
Operating Expenses $258M$219M$181M$166M$168M$173M$224M$174M$106M$57M$19M
Operating Income $-215M$-110M$-68M$-163M$-127M$-153M$-208M$-160M$-102M$-56M$-19M
Other Non-op $527.0K$3M$2M$7.0K$5M$2M$10M$10M$-331.0K$-50.0K$56.0K
Pretax Income $-204M$-97M$-58M$-161M$-122M$-151M$-194M$-147M$-101M$-55M$-19M
Income Tax $0$0$-677.0K$681.0K$-204.0K$-841.0K$0$69.0K$842.0K$482.0K$44.0K
Net Income $-204M$-97M$-58M$-162M$-122M$-150M$-194M$-147M$-102M$-56M$-19M
EPS (Basic) $-1.21$-0.70$-0.54$-2.05$-2.36······
EPS (Diluted) $-1.21$-0.70$-0.54$-2.05$-2.36······
Shares (Basic) 168,649,795138,277,468106,097,26878,855,81051,825,566······
Shares (Diluted) 168,649,795138,277,468106,097,26878,855,81051,825,566······
Balance Sheet 23
Metric Trend 20252024202320222021202020192018201720162015
Cash & Equivalents $602M$302M$200M$88M$151M$184M$147M$175M$143M$150M$161M
Receivables $1M$1M$21M··$30M$20M$10M$1M··
Prepaid Expense $8M$10M$10M$8M$7M$10M$10M$7M$7M$1M$146.0K
Other Current Assets $3M$7M$4M$2M$5M$5M$9M$11M···
Current Assets $615M$320M$235M$99M$163M$230M$185M$202M$150M$152M$161M
PP&E (Net) $7M$10M$13M$17M$22M$29M$36M$40M$27M$9M$3M
PP&E (Gross) $57M$56M$56M$55M$54M$54M$53M$49M$32M$11M$4M
Accum. Depreciation $50M$46M$43M$38M$32M$25M$17M$10M$4M$2M$2M
Other Non-current Assets $16.0K$55.0K$156.0K········
Total Assets $638M$352M$275M$146M$207M$279M$284M$296M$182M$165M$165M
Accounts Payable $16M$16M$13M$17M$7M$14M$9M$13M$8M$5M$3M
Accrued Liabilities $7M$5M$2M$4M$4M$2M$5M$6M$3M··
Current Liabilities $95M$111M$186M$72M$64M$121M$118M$130M$18M$12M$4M
Capital Leases $9M$18M$25M$32M$25M$26M$29M··$16.0K$78.0K
Other Non-current Liabilities ···$190.0K·$474.0K$2M$2M$2M$796.0K$163.0K
Total Liabilities $112M$135M$227M$184M$167M$189M$213M$215M$34M$22M$4M
Common Stock $1.62B$1.18B$935M$803M$750M$694M$540M$375M$310M$216M$185M
Paid-in Capital $228M$156M$129M$119M$88M$72M$57M$38M$22M$10M$3M
Retained Earnings $-1.33B$-1.12B$-1.02B$-967M$-806M$-683M$-533M$-340M$-193M$-90M$-35M
AOCI $-250.0K$-262.0K$-124.0K$-29.0K$181.0K$389.0K$267.0K$153.0K$116.0K$-291.0K$41.0K
Stockholders' Equity $518M$210M$40M$-45M$32M$83M$64M$73M$140M$135M$153M
Liabilities + Equity $638M$352M$275M$146M$207M$279M$284M$296M$182M$165M$165M
Shares Outstanding 187,660,263153,037,286119,162,23486,924,64359,841,11648,778,67834,340,69029,472,19727,829,07923,502,16921,551,423
Cash Flow 10
Metric Trend 20252024202320222021202020192018201720162015
D&A ········$2M$784.0K$594.0K
Stock-based Comp ··········$4M
Deferred Tax $0$0$0·····$908.0K$-698.0K$36.0K
Operating Cash Flow $-187M$-151M$-19M$-128M$-89M$-116M$-188M$-23M$-84M$-32M$-13M
CapEx $718.0K$938.0K$1M$1M$560.0K$1M$4M$10M$19M$6M$2M
Investing Cash Flow $-718.0K$-938.0K$-1M$-1M$-560.0K$-1M$-4M$-10M$-19M$-6M·
Stock Issued ··$94M$51M·$94M$162M$60M$94M$30M$12M
Financing Cash Flow $488M$254M$133M$67M$56M$155M$164M$65M$94M$29M·
Net Change in Cash $300M$102M$112M$-62M$-34M$37M$-28M$32M$-8M$-8M$160M
Taxes Paid ········$-11.0K$554.0K·
Per Share 1
Metric Trend 20252024202320222021202020192018201720162015
EPS (TTM) $-1.21$-0.70$-0.54$-2.05$-2.36······
Growth Rates 3
Metric Trend 20252024202320222021202020192018201720162015
Revenue YoY -60.6%-4.4%3005.1%-91.1%104.0%······
Revenue CAGR 3Y 127.1%38.3%78.0%········
Revenue CAGR 5Y 16.3%··········
Valuation (TTM) 5
Metric Trend 20252024202320222021202020192018201720162015
Revenue TTM $43M$108M$113M$4M$41M$20M$16M$14M$4M$1M$152.0K
Net Income TTM $-204M$-97M$-58M$-162M$-122M$-150M$-194M$-147M$-102M$-56M$-19M
P/E -14.0-17.7-9.4-3.4-1.3······
P / Tangible Book 6.29.015.2·5.84.6·····
Earnings Yield -7.1%-5.7%-10.7%-29.3%-75.2%······

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $43M $108M $113M $4M $41M
Net Income $-204M $-97M $-58M $-162M $-122M
Diluted EPS $-1.21 $-0.70 $-0.54 $-2.05 $-2.36

Institutional owners (13F) 260 filers · $1.1B total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 260
Value held $1.1B
New positions 50
Exited positions 39
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
50 (-7 vs prior Q) 39 (+3 vs prior Q) 99 (-14 vs prior Q) 59 (+5 vs prior Q) +5.4M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
RA CAPITAL MANAGEMENT, L.P. $156,727,684 26,975,505 14.03% Shares
BlackRock, Inc. $111,566,297 19,202,461 9.99% Shares
GSK plc $106,007,465 18,245,691 9.49% Shares
VANGUARD GROUP INC $60,753,682 3,573,746 5.44% Shares
MAVERICK CAPITAL LTD $59,715,848 10,278,115 5.35% Shares
Driehaus Capital Management LLC $31,624,661 5,443,143 2.83% Shares
PRIMECAP MANAGEMENT CO/CA/ $31,110,354 5,354,622 2.79% Shares
683 Capital Management, LLC $28,759,500 4,950,000 2.57% Shares
FMR LLC $28,599,589 4,922,477 2.56% Shares
STATE STREET CORP $28,116,432 4,839,317 2.52% Shares
READYSTATE ASSET MANAGEMENT LP $27,464,678 4,727,139 2.46% Shares
M28 Capital Management LP $26,657,930 4,588,284 2.39% Shares
GEODE CAPITAL MANAGEMENT, LLC $22,489,218 3,869,998 2.01% Shares
TWO SIGMA INVESTMENTS, LP $21,541,656 3,707,686 1.93% Shares
ALGERT GLOBAL LLC $16,370,343 2,817,615 1.47% Shares
Qube Research & Technologies Ltd $16,128,560 2,776,000 1.44% Shares
Squarepoint Ops LLC $14,765,778 2,541,442 1.32% Shares
MORGAN STANLEY $14,075,916 2,422,705 1.26% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $12,263,463 2,110,751 1.10% Shares
Pfizer Inc $10,931,250 1,875,000 0.98% Shares
MILLENNIUM MANAGEMENT LLC $10,523,548 1,811,282 0.94% Shares
D. E. Shaw & Co., Inc. $10,296,645 1,772,228 0.92% Shares
VANGUARD CAPITAL MANAGEMENT LLC $10,175,651 1,751,403 0.91% Shares
SCHRODER INVESTMENT MANAGEMENT GROUP $9,920,932 1,746,643 0.89% Shares
DIMENSIONAL FUND ADVISORS LP $9,920,137 1,707,809 0.89% Shares
RENAISSANCE TECHNOLOGIES LLC $9,903,261 1,704,520 0.89% Shares
AQR CAPITAL MANAGEMENT LLC $9,575,141 1,648,045 0.86% Shares
GOLDMAN SACHS GROUP INC $9,425,807 1,622,342 0.84% Shares
Point72 Asset Management, L.P. $8,627,786 1,484,989 0.77% Shares
FEDERATED HERMES, INC. $8,518,820 1,466,234 0.76% Shares
RTW INVESTMENTS, LP $7,843,500 1,350,000 0.70% Shares
NORTHERN TRUST CORP $7,282,835 1,253,500 0.65% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $7,114,025 1,224,445 0.64% Shares
EMERALD ADVISERS, LLC $7,111,237 1,223,965 0.64% Shares
MARSHALL WACE, LLP $5,807,286 999,533 0.52% Shares
SymBiosis Capital Partners, LLC $5,437,500 750,000 0.49% Shares
Pictet Asset Management Holding SA $5,330,146 917,409 0.48% Shares
VANGUARD FIDUCIARY TRUST CO $5,157,403 887,677 0.46% Shares
Aberdeen Group plc $5,092,221 876,458 0.46% Shares
EMERALD MUTUAL FUND ADVISERS TRUST $4,926,874 847,999 0.44% Shares
BAKER BROS. ADVISORS LP $4,779,527 822,638 0.43% Shares
BNP PARIBAS FINANCIAL MARKETS $4,712,241 811,057 0.42% Shares
CAPITAL FUND MANAGEMENT S.A. $4,268,874 734,746 0.38% Shares
SPHERA FUNDS MANAGEMENT LTD. $3,708,360 638,272 0.33% Shares
JPMORGAN CHASE & CO $3,546,519 618,172 0.32% Shares
Y-Intercept (Hong Kong) Ltd $3,544,646 610,094 0.32% Shares
Susquehanna Portfolio Strategies, LLC $3,533,607 608,194 0.32% Shares
TANG CAPITAL MANAGEMENT LLC $3,486,000 600,000 0.31% Shares
Walleye Capital LLC $3,401,482 585,453 0.30% Shares
Nuveen, LLC $3,191,328 549,282 0.29% Shares

Show all 260 institutional owners →

Activists & 5%+ owners 4 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×9 filings Aug. 11, 2026 16.80% Amendment · SEC
Shin Nippon Biomedical Laboratories, Ltd., SNBL USA, Ltd., Ken Takanashi ×6 filings Aug. 12, 2022 · Initial filing · SEC
Kagoshima Shinsangyo Sousei Investment Limited Partnership, Kagoshima Development Co. Ltd. ×5 filings July 20, 2022 · Initial filing · SEC
RA Capital Management, LLC, Peter Kolchinsky ×3 filings Jan. 28, 2019 · Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 22 insiders · 8 officers · 9 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Paul Bolno President and CEO Feb. 5, 2026 A 275,520 0 1 $-140,956
Kyle Moran Chief Financial Officer Feb. 5, 2026 A 134,385 0 7 $-4,151,988
David G Gaiero Interim CFO March 3, 2020 A 6,392 0 0 $0
Keith Regnante Chief Financial Officer March 7, 2019 A 29,186 0 0 $0
Chris Francis SVP, Corporate Development, Head of Emerging Areas Feb. 26, 2026 M 61,867 0 14 $-7,103,233
Chandra Vargeese Chief Technology Officer, Head of Platform Discovery Sciences Feb. 5, 2026 A 408,246 0 1 $-43,417
Michael A. Panzara Chief Medical Officer, Head of Therapeutics Discovery and Development July 25, 2022 A 109,103 0 0 $0
Mark Baldry Chief Commerical Officer Aug. 5, 2019 A 39,000 0 0 $0
Gregory L. Verdine Director Dec. 8, 2025 S 275,217 0 2 $-269,461
Christian O Henry Director Dec. 8, 2025 M 12,700 0 4 $-1,369,324
Mark Corrigan Director Dec. 8, 2025 S 28,815 0 2 $-217,265
Amy Pott Director Aug. 18, 2020 A · 0 0 $0
Peter Kolchinsky Director Aug. 18, 2020 A · 0 0 $0
Koji Miura Director Aug. 15, 2019 A · 0 0 $0
Masaharu Tanaka Director Nov. 10, 2016 A · 0 0 $0
Takeshi Wada Director Nov. 10, 2016 A · 0 0 $0
GSK plc 10% owner Dec. 11, 2025 P 18,245,691 1 0 $27,930,000
Adrian Rawcliffe · Aug. 12, 2026 S 0 0 3 $-806,604
Tan Aik Na · Aug. 11, 2026 S 24,968 0 9 $-1,825,754
Ken Takanashi · Aug. 11, 2026 S 20,079 0 1 $-23,223
Heidi L Wagner · Aug. 11, 2026 M 44,930 0 3 $-231,070
Roberto Guerciolini · Dec. 7, 2016 M 4,000 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 30 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PILL · Direxion Shares ETF Trust 1.11% 41,500 NS July 31, 2026 N-PORT
IHE · iShares Trust 0.16% 562,937 SH Sept. 11, 2026 Daily
IWC · iShares Trust 0.15% 470,896 SH Sept. 11, 2026 Daily
IBB · iShares Trust 0.06% 1,217,594 SH Sept. 11, 2026 Daily
NUSC · Nushares ETF Trust 0.05% 122,389 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.05% 13,788 SH Oct. 2, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.05% 111,824 SH Aug. 19, 2026 Daily
RSSL · Global X Funds 0.02% 66,050 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.02% 3,532,850 SH Sept. 11, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.02% 793,588 SH Aug. 19, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 386,104 NS July 31, 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0.01% 86,919 SH Oct. 2, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.01% 1,751,403 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.01% 390,910 SH Aug. 19, 2026 Daily
ISCG · iShares Trust 0.01% 14,841 SH Sept. 11, 2026 Daily
WSML · iShares Trust 0.01% 7,302 SH Sept. 11, 2026 Daily
DXUV · Dimensional ETF Trust 0.00% 4,263 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 19,243 NS July 31, 2026 N-PORT
IWO · iShares Trust 0.00% 88,152 SH Sept. 11, 2026 Daily
DFAC · Dimensional ETF Trust 0.00% 195,202 NS July 31, 2026 N-PORT
IWV · iShares Trust 0.00% 64,397 SH Sept. 10, 2026 Daily
DFSU · Dimensional ETF Trust 0.00% 6,250 NS July 31, 2026 N-PORT
ITOT · iShares Trust 0.00% 248,363 SH Sept. 11, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 19,385 NS July 31, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 33,180 NS July 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.00% 10,069 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 11,431 SH Aug. 19, 2026 Daily
IWN · iShares Trust · 1,201,565 SH Sept. 11, 2026 Daily
ISCB · iShares Trust · 6,085 SH Sept. 11, 2026 Daily
ISCV · iShares Trust · 18,901 SH Sept. 11, 2026 Daily

WVE Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 21 analysts BUY
Median target $15.00 +296.8%
7 33.3% Strong Buy
13 61.9% Buy
1 4.8% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

17 analysts · 2026-09-28

Mean target $18.53 +390.2%

← Below all targets Current price $3.78
Low$10.00 Mean$18.53 High$42.00

Latest News Recent headlines mentioning this company

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Source: SEC 10-Q filed Jul 30, 2026