DYN Dyne Therapeutics, Inc. - Common Stock
$25,79
Prix · Aoû 18, 2026
Données fondamentales au Jul 29, 2026
Fourchette 52 semaines
$12–$27
90% of range
Note des analystes
BUY
21 analysts
Objectif de cours
$39
+53% upside
P/E (TTM)
-7.4
ROE
-57.8%
Marge nette
—
DYN Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$25.79
Capitalisation Boursière
$4.25B
P/E (TTM)
-7.4
BPA (TTM)
$-3.47
Revenus (TTM)
—
Rendement div.
—
ROE
-57.8%
Dette/Capitaux propres
—
Fourchette 52 semaines
$12 – $27
DYN Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
—
BPA
$-3.47
2021-12-31
→
2025-12-31
Flux de trésorerie libre
$-405M
2020-12-31
→
2025-12-31
Marges
—
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
DYN
Médiane des pairs
P/E (TTM)
-7.4
13.2
P/B
4.4
3.5
Price / FCF (Cours / FCF)
-10.5
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
DYN
Médiane des pairs
ROA
-47.5%
-42.2%
ROE
-57.8%
-52.8%
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
DYN
Médiane des pairs
Current Ratio (Ratio de liquidité)
22.3
10.3
Quick Ratio (Ratio de liquidité réduite)
17.6
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
DYN
Médiane des pairs
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
DYN
Médiane des pairs
DYN Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
21 analystes
- Achat fort 7 33,3%
- Achat 12 57,1%
- Conserver 2 9,5%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
15 analystes · 2026-08-15
Médiane
$40.00
Maintenant
$25.79
Bas
$17.00
Haut
$50.00
Objectif médian
$40.00
+55,1%
Objectif moyen
$39.40
+52,8%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
-0.06%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-1.08 | $-0.76 | -0.32% |
| 31 mars 2026 | $-0.73 | $-0.78 | 0.05% |
| 31 décembre 2025 | $-0.76 | $-0.78 | 0.02% |
| 30 septembre 2025 | $-0.76 | $-0.85 | 0.09% |
| 30 juin 2025 | $-0.97 | $-0.96 | -0.01% |
| 31 mars 2025 | $-1.05 | $-0.89 | -0.16% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| DYN | $3.23B | -5.6 | — | — | -57.8% | — |
| CAI | $7.62B | -8.4 | 97.0% | -8.4% | -13.2% | — |
| PTCT | $6.19B | 9.8 | 114.5% | 39.4% | -331.5% | — |
| TVTX | $3.47B | -131.8 | 110.5% | -5.2% | -34.6% | — |
| ACAD | $4.55B | 11.6 | 11.9% | 36.5% | 38.1% | — |
| CELC | $4.81B | -26.3 | — | — | -244.3% | — |
| RLAY | $1.47B | -5.3 | 53.4% | -1800.6% | -44.9% | — |
| PBLS | — | — | — | — | — | — |
| TNGX | $1.20B | -10.2 | 48.3% | -162.8% | -42.2% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $398M | $281M | $211M | $143M | $121M | $45M | $11M | |
| SG&A Expense | $70M | $62M | $31M | $28M | $29M | $13M | $3M | |
| Operating Expenses | $468M | $344M | $242M | $171M | $150M | $59M | $14M | |
| Operating Income | $-468M | $-344M | $-242M | $-171M | $-150M | $-59M | $-14M | |
| Other Non-op | $22M | $26M | $6M | $3M | $734.0K | $-790.0K | $-1M | |
| Income Tax | $0 | $0 | $0 | · | · | · | · | |
| Net Income | $-446M | $-317M | $-236M | $-168M | $-149M | $-59M | $-15M | |
| EPS (Basic) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 | · | · | |
| EPS (Diluted) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 | · | · | |
| EBITDA | $-466M | $-342M | $-240M | $-169M | $-149M | $-58M | · |
Bilan 20
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $893M | $435M | $122M | $172M | $201M | $301M | $15M | |
| Prepaid Expense | $16M | $17M | $6M | $10M | $6M | $4M | $127.0K | |
| Current Assets | $1.13B | $659M | $129M | $266M | $382M | $349M | $15M | |
| PP&E (Net) | $24M | $5M | $5M | $6M | $5M | $2M | $1M | |
| PP&E (Gross) | $33M | $12M | $10M | $10M | $7M | $3M | $2M | |
| Accum. Depreciation | $9M | $7M | $5M | $4M | $2M | $995.0K | $295.0K | |
| Other Non-current Assets | · | · | · | · | · | · | $191.0K | |
| Total Assets | $1.19B | $691M | $165M | $306M | $426M | $353M | $16M | |
| Accounts Payable | $8M | $7M | $23M | $5M | $4M | $3M | $1M | |
| Current Liabilities | $51M | $42M | $51M | $28M | $29M | $11M | $2M | |
| Capital Leases | $15M | $19M | $23M | $26M | $29M | $0 | · | |
| Total Liabilities | $215M | $61M | $74M | $54M | $57M | $11M | $2M | |
| Long-term Debt | $149M | $0 | · | · | · | · | · | |
| Common Stock | $16.0K | $10.0K | $6.0K | $6.0K | $6.0K | $5.0K | $1.0K | |
| Paid-in Capital | $2.37B | $1.58B | $724M | $650M | $597M | $422M | $6M | |
| Retained Earnings | $-1.40B | $-950M | $-633M | $-397M | $-228M | $-79M | $-20M | |
| AOCI | $475.0K | $6.0K | $0 | $-571.0K | $-269.0K | $-27.0K | · | |
| Stockholders' Equity | $972M | $630M | $91M | $252M | $368M | $342M | $14M | |
| Liabilities + Equity | $1.19B | $691M | $165M | $306M | $426M | $353M | $16M | |
| Shares Outstanding | 164,950,540 | 102,318,629 | 61,468,743 | 55,636,505 | 51,569,381 | 45,076,574 | 2,586,535 |
Flux de trésorerie 13
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $2M | $1M | $700.0K | $271.0K | |
| Stock-based Comp | $46M | $46M | $20M | $15M | $18M | $7M | $26.0K | |
| Other Non-cash | $-5M | $-22M | $26M | $-2M | $11M | $6M | · | |
| Operating Cash Flow | $-403M | $-292M | $-188M | $-154M | $-120M | $-47M | $-12M | |
| CapEx | $2M | $2M | $729.0K | $3M | $4M | $1M | $2M | |
| Investing Cash Flow | $-29M | $-204M | $83M | $87M | $-138M | $-46M | $-2M | |
| Debt Issued | $148M | $0 | $0 | · | · | $10M | · | |
| Net Debt Issued | $148M | · | · | · | · | $10M | · | |
| Stock Issued | $141M | $98M | $52M | $37M | · | · | · | |
| Net Stock Activity | $141M | $98M | · | · | · | · | · | |
| Financing Cash Flow | $890M | $810M | $54M | $37M | $158M | $381M | $20M | |
| Net Change in Cash | $458M | $313M | $-51M | $-29M | $-100M | $289M | $7M | |
| Free Cash Flow | $-405M | $-295M | $-189M | $-157M | $-123M | $-48M | · |
Rentabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -47.5% | -74.1% | -100.1% | -45.9% | -38.3% | -32.1% | · | |
| ROE | -57.8% | -47.5% | -193.9% | -67.0% | -38.2% | -16.8% | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 22.3 | 15.6 | 2.5 | 9.5 | 13.3 | 31.8 | · | |
| Quick Ratio | 17.6 | 10.3 | 2.4 | 6.1 | 7.0 | 27.4 | · |
Valorisation (TTM) 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-446M | $-317M | $-236M | $-168M | $-149M | $-59M | · | |
| Market Cap | $3.23B | $2.41B | $818M | $645M | $613M | $947M | · | |
| P/E | -5.6 | -7.0 | -3.4 | -3.6 | -4.1 | · | · | |
| P/B | 3.3 | 3.8 | 9.0 | 2.6 | 1.7 | 2.8 | · | |
| P / Tangible Book | 3.3 | 3.8 | 9.0 | 2.6 | 1.7 | 2.8 | · | |
| P / Cash Flow | -8.0 | -8.2 | -4.3 | -4.2 | -5.1 | -20.4 | · | |
| P / FCF | -8.0 | -8.2 | -4.3 | -4.1 | -5.0 | -19.9 | · | |
| Earnings Yield | -17.7% | -14.3% | -29.7% | -27.9% | -24.6% | · | · |
Compte de résultat 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $152M | $101M | $95M | $97M | $99M | $106M | $82M | $93M | $62M | $45M | $55M | $59M | $38M | $35M | $47M | $28M | |
| SG&A Expense | $29M | $24M | $21M | $17M | $17M | $16M | $15M | $13M | $10M | $25M | $7M | $8M | $8M | $8M | $6M | $8M | |
| Operating Expenses | $182M | $125M | $116M | $114M | $116M | $122M | $97M | $106M | $72M | $69M | $62M | $67M | $45M | $42M | $53M | $36M | |
| Operating Income | $-182M | $-125M | $-116M | $-114M | $-116M | $-122M | $-97M | $-106M | $-72M | $-69M | $-62M | $-67M | $-45M | $-42M | $-53M | $-36M | |
| Interest Expense | · | · | · | $3M | $94.0K | · | · | $0 | · | · | · | · | · | · | · | · | |
| Other Non-op | $3M | $4M | $4M | $6M | $5M | $7M | $8M | $9M | $7M | $4M | $2M | $2M | $1M | $894.0K | $451.0K | $200.0K | |
| Net Income | $-179M | $-121M | $-112M | $-108M | $-111M | $-115M | $-90M | $-97M | $-65M | $-66M | $-60M | $-65M | $-44M | $-41M | $-52M | $-36M | |
| EPS (Basic) | $-1.08 | $-0.73 | $-0.69 | $-0.76 | $-0.97 | $-1.05 | $-0.90 | $-0.96 | $-0.70 | $-0.81 | $-0.99 | $-1.08 | $-0.78 | $-0.80 | $-1.01 | $-0.69 | |
| EPS (Diluted) | $-1.08 | $-0.73 | $-0.69 | $-0.76 | $-0.97 | $-1.05 | $-0.90 | $-0.96 | $-0.70 | $-0.81 | $-0.99 | $-1.08 | $-0.78 | $-0.80 | $-1.01 | $-0.69 | |
| EBITDA | $-181M | $-125M | · | $-113M | $-115M | $-122M | · | $-105M | $-72M | $-69M | $-62M | $-66M | $-45M | $-42M | $-52M | $-35M |
Bilan 19
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $676M | $753M | $893M | $574M | $485M | $472M | $435M | $532M | $608M | $272M | $130M | $168M | $181M | $145M | $136M | $148M | |
| Prepaid Expense | $39M | $49M | $16M | $14M | $14M | $12M | $17M | $13M | $13M | $35M | $10M | $5M | $11M | $10M | $6M | $21M | |
| Current Assets | $938M | $1.02B | $1.13B | $806M | $698M | $690M | $659M | $736M | $792M | $488M | $168M | $213M | $249M | $258M | $298M | $344M | |
| PP&E (Net) | $25M | $24M | $24M | $24M | $6M | $6M | $5M | $5M | $5M | $5M | $5M | $5M | $6M | $6M | $5M | $6M | |
| PP&E (Gross) | $34M | $33M | $33M | $32M | $13M | $13M | $12M | $11M | $11M | $10M | $10M | $10M | $10M | $9M | $8M | $8M | |
| Accum. Depreciation | $10M | $9M | $9M | $8M | $8M | $7M | $7M | $7M | $6M | $6M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Total Assets | $994M | $1.08B | $1.19B | $867M | $729M | $721M | $691M | $769M | $826M | $522M | $205M | $251M | $289M | $300M | $340M | $388M | |
| Accounts Payable | $12M | $11M | $8M | $12M | $14M | $7M | $7M | $6M | $2M | $7M | $4M | $3M | $9M | $919.0K | $7M | $5M | |
| Current Liabilities | $78M | $51M | $51M | $60M | $41M | $34M | $42M | $43M | $30M | $22M | $30M | $20M | $22M | $23M | $26M | $23M | |
| Capital Leases | $15M | $14M | $15M | $16M | $17M | $18M | $19M | $20M | $21M | $22M | $24M | $24M | $25M | $27M | $27M | $28M | |
| Total Liabilities | $292M | $215M | $215M | $175M | $158M | $52M | $61M | $63M | $51M | $44M | $53M | $45M | $47M | $50M | $53M | $51M | |
| Long-term Debt | $199M | $149M | $149M | $99M | $99M | · | $0 | · | · | · | · | · | · | · | · | · | |
| Common Stock | $16.0K | $16.0K | $16.0K | $14.0K | $11.0K | $11.0K | $10.0K | $10.0K | $10.0K | $9.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | |
| Paid-in Capital | $2.40B | $2.38B | $2.37B | $1.98B | $1.75B | $1.73B | $1.58B | $1.57B | $1.54B | $1.18B | $718M | $713M | $683M | $608M | $605M | $601M | |
| Retained Earnings | $-1.70B | $-1.52B | $-1.40B | $-1.28B | $-1.18B | $-1.07B | $-950M | $-860M | $-763M | $-698M | $-566M | $-506M | $-441M | $-358M | $-316M | $-264M | |
| AOCI | $-353.0K | $-137.0K | $475.0K | $496.0K | $252.0K | $241.0K | $6.0K | $478.0K | $-240.0K | $-132.0K | $-13.0K | $-56.0K | $-203.0K | $-983.0K | $-1M | $-930.0K | |
| Stockholders' Equity | $702M | $865M | $972M | $692M | $571M | $669M | $630M | $706M | $775M | $478M | $152M | $207M | $242M | $250M | $287M | $336M | |
| Liabilities + Equity | $994M | $1.08B | $1.19B | $867M | $729M | $721M | $691M | $769M | $826M | $522M | $205M | $251M | $289M | $300M | $340M | $388M | |
| Shares Outstanding | 165,670,880 | 165,201,329 | 164,950,540 | 142,613,248 | 114,338,610 | 113,633,782 | 102,318,629 | 101,753,378 | 100,119,518 | 87,089,649 | 61,322,283 | 61,013,986 | 58,305,480 | 51,906,773 | 51,734,361 | 51,649,423 |
Flux de trésorerie 12
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $600.0K | $550.0K | $547.0K | $500.0K | $500.0K | $502.0K | $487.0K | $400.0K | $400.0K | $386.0K | $400.0K | $400.0K | $412.0K | $400.0K | $500.0K | $425.0K | |
| Stock-based Comp | $15M | $13M | $11M | $11M | $11M | $13M | $10M | $9M | $7M | $20M | $5M | $5M | $5M | $4M | $3M | $4M | |
| Other Non-cash | · | $-38M | · | · | · | $-4M | · | · | · | $-33M | · | · | $-8M | · | · | $-20M | |
| Operating Cash Flow | $-130M | $-145M | $-112M | $-91M | $-95M | $-106M | $-84M | $-75M | $-55M | $-79M | $-51M | $-56M | $-47M | $-43M | $-31M | $-51M | |
| CapEx | $2M | $221.0K | $484.0K | $395.0K | $60.0K | $981.0K | $1M | $253.0K | $857.0K | $191.0K | $167.0K | $250.0K | $230.0K | $886.0K | $261.0K | $1M | |
| Investing Cash Flow | $-5M | $-2M | $982.0K | $-38M | $7M | $1M | $-16M | $-19M | $11M | $-180M | $13M | $17M | $27M | $52M | $18M | $-2M | |
| Debt Issued | · | · | $49M | $0 | · | · | $0 | $0 | · | · | · | · | · | · | · | · | |
| Stock Issued | $0 | $0 | $0 | $0 | $0 | $141M | $0 | $0 | $24M | $74M | $0 | $24M | $28M | · | · | · | |
| Net Stock Activity | · | $0 | · | · | · | $141M | · | · | · | $74M | · | · | · | · | · | · | |
| Financing Cash Flow | $58M | $7M | $431M | $217M | $101M | $141M | $4M | $18M | $380M | $408M | $454.0K | $25M | $29M | $70.0K | $99.0K | $18.0K | |
| Net Change in Cash | $-77M | $-140M | $320M | $89M | $13M | $37M | $-97M | $-76M | $336M | $150M | $-37M | $-14M | $9M | $9M | $-12M | $-53M | |
| Free Cash Flow | · | $-145M | · | · | · | $-107M | · | · | · | $-79M | · | · | $-47M | · | · | $-52M |
Rentabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -20.7% | -13.4% | · | -13.2% | -14.3% | -18.6% | · | -19.9% | -12.1% | -16.2% | -23.8% | -21.9% | -13.1% | -10.8% | -13.0% | -8.1% | |
| ROE | -28.0% | -15.8% | · | -15.5% | -16.5% | -20.1% | · | -22.7% | -13.3% | -18.2% | -30.0% | -26.3% | -15.3% | -12.5% | -14.1% | -8.7% |
Liquidité et Solvabilité 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.0 | 19.9 | · | 13.5 | 16.8 | 20.4 | · | 17.0 | 26.6 | 21.8 | 5.7 | 10.5 | 11.5 | 11.1 | 11.6 | 14.8 | |
| Quick Ratio | 8.7 | 14.7 | · | 9.6 | 11.7 | 13.9 | · | 12.3 | 20.4 | 12.2 | 4.4 | 8.3 | 8.4 | 6.2 | 5.3 | 6.4 | |
| Interest Coverage | · | · | · | -39.2 | -1231.8 | · | · | · | · | · | · | · | · | · | · | · |
Valorisation (TTM) 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-518M | $-455M | · | $-431M | $-388M | $-343M | · | $-288M | $-256M | $-235M | $-211M | $-203M | $-173M | $-172M | $-160M | $-133M | |
| Market Cap | $3.68B | $3.00B | · | $1.80B | $1.09B | $1.19B | · | $3.65B | $3.53B | $2.47B | $549M | $686M | $672M | $659M | $355M | $498M | |
| P/E | -6.3 | -5.2 | · | -3.4 | -2.6 | -3.0 | · | -10.4 | -9.9 | -7.8 | -2.5 | -3.1 | -3.5 | -3.8 | -2.2 | · | |
| P/B | 5.2 | 3.5 | · | 2.6 | 1.9 | 1.8 | · | 5.2 | 4.6 | 5.2 | 3.6 | 3.3 | 2.8 | 2.6 | 1.2 | 1.5 | |
| P / Tangible Book | 5.2 | 3.5 | · | 2.6 | 1.9 | 1.8 | · | 5.2 | 4.6 | 5.2 | 3.6 | 3.3 | 2.8 | 2.6 | 1.2 | 1.5 | |
| P / Cash Flow | · | -20.7 | · | · | · | -11.2 | · | · | · | -31.5 | · | · | -14.3 | · | · | -9.8 | |
| P / FCF | · | -20.6 | · | · | · | -11.1 | · | · | · | -31.4 | · | · | -14.2 | · | · | -9.5 | |
| Earnings Yield | -15.9% | -19.4% | · | -29.6% | -38.7% | -33.7% | · | -9.6% | -10.1% | -12.9% | -40.7% | -32.6% | -28.5% | -26.2% | -45.3% | · |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Résultat net | $-446M | $-317M | $-236M | $-168M | $-149M |
| BPA dilué | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 22.3 | 15.6 | 2.5 | 9.5 | 13.3 |
| Ratio de liquidité réduite | 17.6 | 10.3 | 2.4 | 6.1 | 7.0 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-405M | $-295M | $-189M | $-157M | $-123M |
Dernières actualités Actualités récentes mentionnant cette entreprise
Mes métriques Votre watchlist personnelle — lignes sélectionnées de Fondamentaux Complets
📊
Choisissez les indicateurs qui vous importent — cliquez sur le ➕ à côté de n'importe quelle ligne dans Fondamentaux Complets ci-dessus.
Votre sélection est enregistrée et vous suit sur tous les tickers.
Détenteurs institutionnels (13F) 261 déclarants · $2.5B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 54 (+19 vs T. préc.) | 27 (-14 vs T. préc.) | 87 (-11 vs T. préc.) | 70 (+7 vs T. préc.) | +15.5M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| STATE STREET CORP | $165 648 021 | 7 458 263 | 6,74% | Actions |
| FMR LLC | $160 201 907 | 7 213 053 | 6,52% | Actions |
| Orbis Allan Gray Ltd | $155 111 575 | 6 983 862 | 6,31% | Actions |
| Atlas Venture Life Science Advisors, LLC | $151 030 199 | 6 800 099 | 6,14% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $140 166 621 | 6 310 969 | 5,70% | Actions |
| TCG Crossover Management, LLC | $102 502 348 | 4 615 144 | 4,17% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $89 915 586 | 4 048 428 | 3,66% | Actions |
| Vestal Point Capital, LP | $74 958 750 | 3 375 000 | 3,05% | Actions |
| ORBIMED ADVISORS LLC | $71 864 542 | 3 235 684 | 2,92% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $71 309 878 | 3 209 934 | 2,90% | Actions |
| Frazier Life Sciences Management, L.P. | $70 029 951 | 3 153 082 | 2,85% | Actions |
| ARMISTICE CAPITAL, LLC | $68 567 289 | 3 087 226 | 2,79% | Actions |
| PERCEPTIVE ADVISORS LLC | $59 727 909 | 2 689 235 | 2,43% | Actions |
| Logos Global Management LP | $56 635 500 | 2 550 000 | 2,30% | Actions |
| Venrock Adviser, LLC | $48 282 608 | 2 173 913 | 1,96% | Actions |
| Siren, L.L.C. | $47 287 866 | 2 129 125 | 1,92% | Actions |
| MPM BIOIMPACT LLC | $42 689 686 | 1 922 093 | 1,74% | Actions |
| GOLDMAN SACHS GROUP INC | $41 625 071 | 1 874 159 | 1,69% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $40 865 556 | 1 839 962 | 1,66% | Actions |
| Sofinnova Investments, Inc. | $36 832 709 | 1 658 384 | 1,50% | Actions |
| Palo Alto Investors LP | $36 591 441 | 1 647 521 | 1,49% | Actions |
| Vivo Capital, LLC | $34 591 320 | 1 557 466 | 1,41% | Actions |
| Aberdeen Group plc | $34 190 829 | 1 539 434 | 1,39% | Actions |
| Deep Track Capital, LP | $33 315 000 | 1 500 000 | 1,35% | Actions |
| BANK OF AMERICA CORP /DE/ | $31 725 719 | 1 428 443 | 1,29% | Actions |
| FCPM III SERVICES B.V. | $31 679 678 | 1 426 370 | 1,29% | Actions |
| Polar Capital Holdings Plc | $28 580 072 | 1 286 811 | 1,16% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $26 700 929 | 1 202 203 | 1,09% | Actions |
| CITADEL ADVISORS LLC | $25 407 307 | 1 143 958 | 1,03% | Actions |
| Saturn V Capital Management LP | $23 486 920 | 1 057 493 | 0,96% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $21 964 557 | 988 949 | 0,89% | Actions |
| NOVO HOLDINGS A/S | $21 330 351 | 960 394 | 0,87% | Actions |
| Rock Springs Capital Management LP | $20 925 240 | 942 154 | 0,85% | Actions |
| BRAIDWELL LP | $20 468 692 | 921 598 | 0,83% | Actions |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $19 414 605 | 874 138 | 0,79% | Actions |
| BAKER BROS. ADVISORS LP | $18 066 702 | 813 449 | 0,73% | Actions |
| SAMLYN CAPITAL, LLC | $14 875 658 | 669 773 | 0,61% | Actions |
| Artisan Partners Limited Partnership | $14 653 847 | 659 786 | 0,60% | Actions |
| TD Asset Management Inc | $12 173 568 | 548 112 | 0,50% | Actions |
| ALGERT GLOBAL LLC | $11 244 323 | 506 273 | 0,46% | Actions |
| MILLENNIUM MANAGEMENT LLC | $9 591 389 | 431 850 | 0,39% | Actions |
| Clearbridge Investments, LLC | $9 220 070 | 415 131 | 0,37% | Actions |
| ArrowMark Colorado Holdings LLC | $8 822 278 | 397 221 | 0,36% | Actions |
| MPM ASSET MANAGEMENT LLC | $8 632 056 | 682 376 | 0,35% | Actions |
| WASATCH ADVISORS LP | $8 043 701 | 443 668 | 0,33% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $8 008 304 | 360 572 | 0,33% | Actions |
| Tetragon Partners GP Ltd | $7 921 352 | 356 657 | 0,32% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $7 905 716 | 355 953 | 0,32% | Actions |
| Granahan Investment Management, LLC | $7 519 529 | 338 565 | 0,31% | Actions |
| University of Wisconsin Foundation | $6 964 146 | 313 559 | 0,28% | Actions |
| MOORE CAPITAL MANAGEMENT, LP | $6 791 685 | 305 794 | 0,28% | Actions |
| Squarepoint Ops LLC | $6 664 644 | 300 074 | 0,27% | Actions |
| Fisher Asset Management, LLC | $6 629 795 | 298 505 | 0,27% | Actions |
| AMERIPRISE FINANCIAL INC | $6 625 622 | 298 317 | 0,27% | Actions |
| RAYMOND JAMES FINANCIAL INC | $6 468 951 | 291 263 | 0,26% | Actions |
| Ensign Peak Advisors, Inc | $6 434 903 | 289 730 | 0,26% | Actions |
| Alyeska Investment Group, L.P. | $5 447 624 | 245 278 | 0,22% | Actions |
| Catalio Capital Management, LP | $5 439 873 | 244 929 | 0,22% | Actions |
| Swiss National Bank | $5 152 720 | 232 000 | 0,21% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $4 432 983 | 199 594 | 0,18% | Actions |
| SummitTX Capital, L.P. | $4 323 021 | 194 643 | 0,18% | Actions |
| RHUMBLINE ADVISERS | $4 082 158 | 183 799 | 0,17% | Actions |
| CITIGROUP INC | $3 998 733 | 180 042 | 0,16% | Actions |
| HighVista Strategies LLC | $3 819 254 | 171 961 | 0,16% | Actions |
| ALPS ADVISORS INC | $3 710 891 | 167 082 | 0,15% | Actions |
| Y-Intercept (Hong Kong) Ltd | $3 469 269 | 156 203 | 0,14% | Actions |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3 467 781 | 156 136 | 0,14% | Actions |
| AXXCESS WEALTH MANAGEMENT, LLC | $3 448 547 | 155 270 | 0,14% | Actions |
| Darwin Wealth Management, LLC | $3 448 546 | 155 270 | 0,14% | Actions |
| Aegis Wealth Management LLC | $3 332 166 | 150 030 | 0,14% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3 331 500 | 150 000 | 0,14% | Actions |
| Woodline Partners LP | $3 317 907 | 149 388 | 0,13% | Actions |
| BlackRock, Inc. | $3 223 182 | 145 123 | 0,13% | Actions |
| Bank of New York Mellon Corp | $3 129 789 | 140 918 | 0,13% | Actions |
| ALLIANCEBERNSTEIN L.P. | $3 119 810 | 172 080 | 0,13% | Actions |
| Schonfeld Strategic Advisors LLC | $2 992 841 | 134 752 | 0,12% | Actions |
| XTX Topco Ltd | $2 793 707 | 125 786 | 0,11% | Actions |
| Jain Global LLC | $2 583 934 | 116 341 | 0,11% | Actions |
| Rafferty Asset Management, LLC | $2 556 415 | 115 102 | 0,10% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2 532 090 | 139 663 | 0,10% | Actions |
| MORGAN STANLEY | $2 460 571 | 110 786 | 0,10% | Actions |
| AXA Investment Managers S.A. | $2 064 872 | 163 231 | 0,08% | Actions |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $1 933 798 | 87 069 | 0,08% | Actions |
| JANUS HENDERSON GROUP PLC | $1 810 516 | 99 863 | 0,07% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $1 804 296 | 81 238 | 0,07% | Actions |
| MetLife Investment Management, LLC | $1 771 803 | 79 775 | 0,07% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 746 195 | 78 622 | 0,07% | Actions |
| FIFTH THIRD BANCORP | $1 684 826 | 75 859 | 0,07% | Actions |
| CIBC WORLD MARKET INC. | $1 683 140 | 75 783 | 0,07% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 548 081 | 69 702 | 0,06% | Actions |
| ENVESTNET ASSET MANAGEMENT INC | $1 478 808 | 66 583 | 0,06% | Actions |
| VANGUARD GROUP INC | $1 433 904 | 73 308 | 0,06% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1 395 321 | 62 824 | 0,06% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 390 346 | 62 600 | 0,06% | Option de vente |
| JANE STREET GROUP, LLC | $1 377 020 | 62 000 | 0,06% | Option de vente |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $1 309 213 | 58 947 | 0,05% | Actions |
| PROFUND ADVISORS LLC | $1 306 170 | 58 810 | 0,05% | Actions |
| Invesco Ltd. | $1 212 555 | 54 595 | 0,05% | Actions |
| VICTORY CAPITAL MANAGEMENT INC | $1 210 400 | 54 498 | 0,05% | Actions |
| Vanguard Global Advisers, LLC | $1 202 383 | 54 137 | 0,05% | Actions |
Initiés de la société 26 initiés · 7 dirigeants · 10 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Joshua T Brumm | CEO & President | 11 mars 2024 M | 537 998 | 0 | 0 | $0 |
| Susanna Gatti High | Chief Operating Officer | 18 septembre 2024 S | 131 636 | 0 | 0 | $0 |
| Oxana Beskrovnaya | Chief Scientific Officer | 11 mars 2025 S | 195 840 | 0 | 0 | $0 |
| Richard William Scalzo | SVP, Head of Finance & Admin. | 11 mars 2025 S | 122 330 | 0 | 0 | $0 |
| Wildon Farwell | Chief Medical Officer | 19 août 2024 S | 143 222 | 0 | 0 | $0 |
| Jonathan Mcneill | Chief Business Officer | 19 août 2024 S | 132 106 | 0 | 0 | $0 |
| Romesh Subramanian | Chief Scientific Officer | 16 septembre 2020 A | 566 249 | 0 | 0 | $0 |
| Dirk Kersten | Administrateur | 27 juillet 2026 S | 3 586 796 | 0 | 19 | $-38 570 974 |
| Barry E Greene | Administrateur | 22 juin 2026 A | — | 0 | 0 | $0 |
| Carlo Incerti | Administrateur | 5 juin 2026 A | 0 | 0 | 0 | $0 |
| Catherine Stehman-Breen | Administrateur | 5 juin 2026 A | 115 713 | 0 | 0 | $0 |
| David Charles Lubner | Administrateur | 5 juin 2026 A | 0 | 0 | 0 | $0 |
| Brian S Posner | Administrateur | 5 juin 2026 A | 24 500 | 7 | 0 | $274 840 |
| Edward Hurwitz | Administrateur | 5 juin 2026 A | 91 081 | 0 | 0 | $0 |
| Vikram Karnani | Administrateur | 22 décembre 2025 A | — | 0 | 0 | $0 |
| Lawrence Otto Klein | Administrateur | 5 juillet 2022 A | 10 725 | 0 | 0 | $0 |
| Atlas Venture Fund XI, L.P. | Détenteur de 10% | 13 juillet 2021 J | 7 326 117 | 0 | 0 | $0 |
| CureDuchenne Ventures, LLC | Détenteur de 10% | 21 septembre 2020 C | 602 972 | 0 | 0 | $0 |
| Forbion Capital Fund IV Cooperatief U.A. | Détenteur de 10% | 21 septembre 2020 C | 6 131 079 | 0 | 0 | $0 |
| Logos Global Management LP | Détenteur de 10% | 21 septembre 2020 C | 1 504 392 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | Détenteur de 10% | 21 septembre 2020 C | 1 608 785 | 0 | 0 | $0 |
| Jason P Rhodes | — | 14 août 2026 S | 428 946 | 0 | 31 | $-99 402 433 |
| Johanna Friedl-Naderer | — | 13 août 2026 S | 153 982 | 0 | 7 | $-31 766 |
| Douglas Kerr | — | 13 août 2026 S | 167 599 | 0 | 7 | $-176 412 |
| Erick Lucera | — | 13 août 2026 S | 119 766 | 0 | 4 | $-228 675 |
| John Cox | — | 13 août 2026 S | 363 165 | 0 | 5 | $-336 865 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 1 participation
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Vida Ventures II, LLC, Vida Ventures II-A, LLC, VV Manager II, LLC ×2 dépôts | 10 février 2023 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 52 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| IBRN · iShares Trust | 3,47% | 10 352 SH | 8 août 2026 | Quotidien |
| BBC · ETFis Series Trust I | 0,67% | 14 322 NS | 30 avril 2026 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,67% | 4 266 NS | 30 avril 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,67% | 196 941 NS | 30 avril 2026 | N-PORT |
| IBB · iShares Trust | 0,30% | 1 099 711 SH | 8 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,30% | 8 997 SH | 8 août 2026 | Quotidien |
| ESSC · Strategy Shares | 0,18% | 2 581 NS | 30 avril 2026 | N-PORT |
| IWN · iShares Trust | 0,16% | 919 017 SH | 8 août 2026 | Quotidien |
| BIB · ProShares Trust | 0,16% | 6 087 NS | 31 mai 2026 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,13% | 77 375 SH | 8 août 2026 | Quotidien |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,12% | 51 630 NS | 30 avril 2026 | N-PORT |
| IWM · iShares Trust | 0,12% | 3 833 065 SH | 8 août 2026 | Quotidien |
| BKSE · BNY Mellon ETF Trust | 0,10% | 4 423 NS | 30 avril 2026 | N-PORT |
| ISCG · iShares Trust | 0,09% | 36 532 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,09% | 784 894 SH | 8 août 2026 | Quotidien |
| IWO · iShares Trust | 0,08% | 463 505 SH | 8 août 2026 | Quotidien |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,08% | 82 893 SH | 8 août 2026 | Quotidien |
| ESML · iShares Trust | 0,08% | 84 297 SH | 8 août 2026 | Quotidien |
| RSSL · Global X Funds | 0,07% | 57 752 NS | 30 avril 2026 | N-PORT |
| ITWO · ProShares Trust | 0,06% | 6 271 NS | 31 mai 2026 | N-PORT |
| ISCB · iShares Trust | 0,06% | 6 733 SH | 8 août 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,06% | 50 849 SH | 8 août 2026 | Quotidien |
| SCHA · SCHWAB STRATEGIC TRUST | 0,06% | 688 953 NS | 31 mai 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,05% | 47 064 SH | 8 août 2026 | Quotidien |
| DFAS · Dimensional ETF Trust | 0,05% | 390 218 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,04% | 1 689 620 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,04% | 347 244 SH | 8 août 2026 | Quotidien |
| ISCV · iShares Trust | 0,04% | 10 732 SH | 8 août 2026 | Quotidien |
| UWM · ProShares Trust | 0,04% | 4 905 NS | 31 mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,03% | 53 716 NS | 30 avril 2026 | N-PORT |
| WSML · iShares Trust | 0,03% | 8 466 SH | 8 août 2026 | Quotidien |
| VBR · VANGUARD INDEX FUNDS | 0,03% | 1 020 875 SH | 8 août 2026 | Quotidien |
| URTY · ProShares Trust | 0,03% | 4 964 NS | 31 mai 2026 | N-PORT |
| TILT · FlexShares Trust | 0,02% | 25 564 NS | 30 avril 2026 | N-PORT |
| VB · VANGUARD INDEX FUNDS | 0,02% | 1 607 020 SH | 8 août 2026 | Quotidien |
| SMLF · iShares Trust | 0,02% | 32 751 SH | 8 août 2026 | Quotidien |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 4 701 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 125 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 44 010 NS | 31 mai 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,01% | 11 272 NS | 31 mai 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 9 076 NS | 30 avril 2026 | N-PORT |
| ITOT · iShares Trust | 0,01% | 199 812 SH | 8 août 2026 | Quotidien |
| IWV · iShares Trust | 0,01% | 38 879 SH | 8 août 2026 | Quotidien |
| DFAC · Dimensional ETF Trust | 0,00% | 123 282 NS | 30 avril 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 84 436 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 21 333 NS | 30 avril 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 720 NS | 30 avril 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 33 452 NS | 30 avril 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 5 252 NS | 31 mai 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 4 473 029 SH | 8 août 2026 | Quotidien |