ORIC Oric Pharmaceuticals, Inc. - Common Stock
$14,35
Prix · Aoû 19, 2026
Données fondamentales au Aoû 3, 2026
Fourchette 52 semaines
$7–$15
92% of range
Note des analystes
BUY
21 analysts
Objectif de cours
$21
+44% upside
P/E (TTM)
-10.3
ROE
-36.5%
Marge nette
—
ORIC Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$14.35
Capitalisation Boursière
$1.49B
P/E (TTM)
-10.3
BPA (TTM)
$-1.47
Revenus (TTM)
—
Rendement div.
—
ROE
-36.5%
Dette/Capitaux propres
—
Fourchette 52 semaines
$7 – $15
ORIC Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
—
BPA
$-1.47
2021-12-31
→
2025-12-31
Flux de trésorerie libre
$-112M
2020-12-31
→
2025-12-31
Marges
—
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
ORIC
Médiane des pairs
P/E (TTM)
-10.3
—
P/B
3.9
3.6
Price / FCF (Cours / FCF)
-13.3
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
ORIC
Médiane des pairs
ROA
-37.9%
-40.9%
ROE
-36.5%
-47.9%
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
ORIC
Médiane des pairs
Current Ratio (Ratio de liquidité)
14.1
8.3
Quick Ratio (Ratio de liquidité réduite)
2.2
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
ORIC
Médiane des pairs
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
ORIC
Médiane des pairs
ORIC Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
21 analystes
- Achat fort 9 42,9%
- Achat 10 47,6%
- Conserver 2 9,5%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
12 analystes · 2026-08-19
Médiane
$21.50
Maintenant
$14.35
Bas
$14.00
Haut
$27.00
Objectif médian
$21.50
+49,8%
Objectif moyen
$20.67
+44,0%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
0.04%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.38 | $-0.37 | -0.01% |
| 31 mars 2026 | $-0.34 | $-0.33 | -0.01% |
| 31 décembre 2025 | $-0.30 | $-0.37 | 0.07% |
| 30 septembre 2025 | $-0.33 | $-0.41 | 0.08% |
| 30 juin 2025 | $-0.47 | $-0.45 | -0.02% |
| 31 mars 2025 | $-0.42 | $-0.52 | 0.10% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| ORIC | $806M | -5.6 | — | — | -36.5% | — |
| ABSI | $529M | -4.2 | -38.2% | -4113.7% | -63.5% | — |
| XNCR | $1.10B | -12.3 | 13.7% | -73.2% | -14.0% | — |
| TYRA | $1.41B | -13.1 | — | — | -42.7% | — |
| PURR | — | — | — | — | — | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| INBX | $1.15B | -8.7 | 550.0% | -10773.5% | -365.9% | — |
| AVBP | $854M | -4.7 | — | — | -59.7% | — |
| JBIO | $761M | -4.8 | — | — | -47.7% | — |
| REPL | $633M | -2.3 | — | — | -146.2% | — |
| MGTX | $645M | -5.6 | 144.6% | -140.3% | 8062.2% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 11
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| SG&A Expense | $33M | $29M | $26M | $25M | $22M | $13M | $6M | |
| Operating Expenses | $143M | $143M | $111M | $92M | $79M | $74M | $29M | |
| Operating Income | $-143M | $-143M | $-111M | $-92M | $-79M | $-74M | $-29M | |
| Other Non-op | $14M | $15M | $10M | $3M | $156.0K | $483.0K | $2M | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-129M | $-128M | $-101M | $-89M | $-79M | $-74M | $-27M | |
| EPS (Basic) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · | |
| EPS (Diluted) | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 | · | · | |
| Shares (Basic) | 87,793,801 | 69,727,940 | 51,450,848 | 39,655,260 | 37,954,280 | · | · | |
| Shares (Diluted) | 87,793,801 | 69,727,940 | 51,450,848 | 39,655,260 | 37,954,280 | · | · | |
| EBITDA | $-143M | $-143M | $-111M | $-92M | $-79M | $-74M | · |
Bilan 22
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $46M | $59M | $23M | $67M | $226M | $78M | $89M | |
| Short-term Investments | · | · | · | · | · | $215M | · | |
| Prepaid Expense | $7M | $6M | $4M | $4M | $4M | $3M | $840.0K | |
| Current Assets | $288M | $262M | $213M | $210M | $241M | $297M | $90M | |
| PP&E (Net) | $2M | $3M | $3M | $3M | $2M | $2M | $2M | |
| PP&E (Gross) | $10M | $10M | $9M | $9M | $7M | $6M | $6M | |
| Accum. Depreciation | $8M | $7M | $6M | $6M | $5M | $4M | $4M | |
| Other Non-current Assets | $7M | $9M | $10M | $12M | $12M | $319.0K | $2M | |
| Total Assets | $409M | $274M | $252M | $247M | $299M | $299M | $94M | |
| Accounts Payable | $4M | $2M | $944.0K | $1M | $2M | $757.0K | $152.0K | |
| Accrued Liabilities | $17M | $23M | $20M | $14M | $13M | $8M | $5M | |
| Current Liabilities | $20M | $25M | $20M | $15M | $15M | $9M | $5M | |
| Capital Leases | $4M | $6M | $7M | $9M | $10M | · | · | |
| Other Non-current Liabilities | $4M | $6M | $7M | $9M | $11M | $219.0K | · | |
| Total Liabilities | $25M | $31M | $28M | $25M | $26M | $9M | $6M | |
| Long-term Debt | · | · | · | · | $10M | · | · | |
| Common Stock | $11.0K | $7.0K | $6.0K | $5.0K | $4.0K | $4.0K | · | |
| Retained Earnings | $-692M | $-563M | $-435M | $-334M | $-245M | $-166M | $-93M | |
| AOCI | $786.0K | $379.0K | $258.0K | $-1M | $-103.0K | $-31.0K | · | |
| Stockholders' Equity | $384M | $243M | $224M | $222M | $273M | $290M | $-90M | |
| Liabilities + Equity | $409M | $274M | $252M | $247M | $299M | $299M | $94M | |
| Shares Outstanding | 98,528,949 | 71,021,855 | 54,865,553 | 45,089,537 | 39,430,120 | 36,672,415 | 1,984,222 |
Flux de trésorerie 9
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $25M | $20M | $15M | $14M | $13M | $5M | $1M | |
| Operating Cash Flow | $-111M | $-113M | $-86M | $-75M | $-60M | $-45M | $-24M | |
| CapEx | $712.0K | $1M | $849.0K | $2M | $939.0K | $667.0K | $768.0K | |
| Investing Cash Flow | $-148M | $22M | $-43M | $-109M | $158M | $-216M | $-768.0K | |
| Stock Issued | $244M | $125M | $85M | $25M | $50M | $271M | · | |
| Net Stock Activity | $244M | $125M | $85M | $25M | $50M | $133M | · | |
| Financing Cash Flow | $245M | $127M | $86M | $25M | $49M | $251M | $71M | |
| Net Change in Cash | $-14M | $36M | $-43M | $-159M | $148M | $-11M | $47M | |
| Free Cash Flow | $-112M | $-114M | $-87M | $-77M | $-60M | $-46M | · |
Rentabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -37.9% | -48.6% | -40.3% | -32.7% | -26.3% | -37.5% | · | |
| ROE | -36.5% | -49.5% | -42.7% | -40.8% | -27.9% | -31.1% | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.1 | 10.6 | 10.4 | 13.7 | 15.9 | 33.0 | · | |
| Quick Ratio | 2.2 | 2.4 | 1.1 | 4.3 | 14.9 | 32.6 | · |
Valorisation (TTM) 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-129M | $-128M | $-101M | $-89M | $-79M | $-74M | · | |
| Market Cap | $806M | $573M | $505M | $266M | $580M | $1.24B | · | |
| P/E | -5.6 | -4.4 | -4.7 | -2.6 | -7.1 | · | · | |
| P/B | 2.1 | 2.4 | 2.3 | 1.2 | 2.1 | 4.3 | · | |
| P / Tangible Book | 2.1 | 2.4 | 2.3 | 1.2 | 2.1 | 4.3 | · | |
| P / Cash Flow | -7.3 | -5.1 | -5.9 | -3.5 | -9.7 | -27.4 | · | |
| P / FCF | -7.2 | -5.0 | -5.8 | -3.4 | -9.6 | -27.0 | · | |
| Earnings Yield | -18.0% | -22.7% | -21.3% | -38.2% | -14.1% | · | · |
Compte de résultat 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SG&A Expense | $9M | $8M | $9M | $8M | $9M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | $6M | $6M | $6M | $6M | |
| Operating Expenses | $45M | $40M | $35M | $37M | $39M | $33M | $40M | $38M | $36M | $29M | $31M | $29M | $25M | $26M | $22M | $26M | |
| Operating Income | $-45M | $-40M | $-35M | $-37M | $-39M | $-33M | $-40M | $-38M | $-36M | $-29M | $-31M | $-29M | $-25M | $-26M | $-22M | $-26M | |
| Other Non-op | $4M | $4M | $4M | $4M | $3M | $3M | $3M | $4M | $4M | $4M | $3M | $3M | $2M | $2M | $1M | $865.0K | |
| Net Income | $-41M | $-36M | $-31M | $-33M | $-36M | $-30M | $-36M | $-35M | $-32M | $-25M | $-28M | $-25M | $-23M | $-24M | $-21M | $-25M | |
| EPS (Basic) | $-0.38 | $-0.34 | $-0.25 | $-0.33 | $-0.47 | $-0.42 | $-0.52 | $-0.49 | $-0.45 | $-0.37 | $-0.49 | $-0.44 | $-0.50 | $-0.53 | $-0.52 | $-0.63 | |
| EPS (Diluted) | $-0.38 | $-0.34 | $-0.25 | $-0.33 | $-0.47 | $-0.42 | $-0.52 | $-0.49 | $-0.45 | $-0.37 | $-0.49 | $-0.44 | $-0.50 | $-0.53 | $-0.52 | $-0.63 | |
| Shares (Basic) | 108,012,388 | 105,472,766 | -160,326,367 | 98,953,331 | 78,126,257 | 71,040,580 | -138,512,709 | 70,542,684 | 70,348,414 | 67,349,551 | -96,695,752 | 57,402,226 | 45,654,208 | 45,090,166 | -78,833,750 | 39,575,660 | |
| Shares (Diluted) | 108,012,388 | 105,472,766 | -160,326,367 | 98,953,331 | 78,126,257 | 71,040,580 | -138,512,709 | 70,542,684 | 70,348,414 | 67,349,551 | -96,695,752 | 57,402,226 | 45,654,208 | 45,090,166 | -78,833,750 | 39,575,660 | |
| EBITDA | $-45M | $-40M | · | $-37M | $-39M | $-33M | · | $-38M | $-36M | $-29M | · | $-29M | $-25M | $-26M | · | $-26M |
Bilan 20
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $37M | $56M | $46M | $50M | $76M | $49M | $59M | $44M | $50M | $56M | $23M | $26M | $104M | $59M | $67M | $29M | |
| Prepaid Expense | $9M | $8M | $7M | $8M | $9M | $8M | $6M | $7M | $8M | $7M | $4M | $5M | $4M | $4M | $4M | $5M | |
| Current Assets | $274M | $290M | $288M | $296M | $291M | $211M | $262M | $279M | $295M | $324M | $213M | $232M | $268M | $193M | $210M | $199M | |
| PP&E (Net) | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | |
| PP&E (Gross) | $10M | $10M | $10M | $11M | $11M | $11M | $10M | $10M | $10M | $9M | $9M | $10M | $10M | $9M | $9M | $9M | |
| Accum. Depreciation | $8M | $8M | $8M | $8M | $8M | $8M | $7M | $7M | $7M | $7M | $6M | $7M | $6M | $6M | $6M | $6M | |
| Other Non-current Assets | $6M | $7M | $7M | $7M | $8M | $8M | $9M | $10M | $9M | $9M | $10M | $10M | $11M | $11M | $12M | $12M | |
| Total Assets | $405M | $437M | $409M | $431M | $347M | $243M | $274M | $302M | $329M | $351M | $252M | $274M | $292M | $227M | $247M | $238M | |
| Accounts Payable | $4M | $3M | $4M | $3M | $3M | $5M | $2M | $4M | $2M | $3M | $944.0K | $4M | $3M | $2M | $1M | $2M | |
| Accrued Liabilities | $17M | $15M | $17M | $17M | $15M | $12M | $23M | $17M | $17M | $12M | $20M | $15M | $11M | $13M | $14M | $12M | |
| Current Liabilities | $21M | $18M | $20M | $20M | $18M | $18M | $25M | $21M | $20M | $15M | $20M | $19M | $15M | $15M | $15M | $13M | |
| Capital Leases | · | · | $4M | · | · | · | $6M | · | · | · | $7M | · | · | · | $9M | · | |
| Other Non-current Liabilities | $3M | $3M | $4M | $4M | $5M | $6M | $6M | $7M | $7M | $7M | $7M | $8M | $8M | $9M | $9M | $10M | |
| Total Liabilities | $23M | $21M | $25M | $24M | $23M | $23M | $31M | $28M | $27M | $22M | $28M | $27M | $23M | $24M | $25M | $23M | |
| Common Stock | $11.0K | $11.0K | $11.0K | $11.0K | $9.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $6.0K | $6.0K | $6.0K | $5.0K | $5.0K | $4.0K | |
| Retained Earnings | $-770M | $-728M | $-692M | $-662M | $-629M | $-593M | $-563M | $-526M | $-492M | $-460M | $-435M | $-407M | $-381M | $-358M | $-334M | $-313M | |
| AOCI | $-1M | $-290.0K | $786.0K | $615.0K | $187.0K | $209.0K | $379.0K | $722.0K | $-256.0K | $-162.0K | $258.0K | $-369.0K | $-567.0K | $-499.0K | $-1M | $-2M | |
| Stockholders' Equity | $381M | $416M | $384M | $407M | $324M | $220M | $243M | $274M | $302M | $329M | $224M | $247M | $269M | $203M | $222M | $215M | |
| Liabilities + Equity | $405M | $437M | $409M | $431M | $347M | $243M | $274M | $302M | $329M | $351M | $252M | $274M | $292M | $227M | $247M | $238M | |
| Shares Outstanding | 103,636,424 | 103,486,412 | 98,528,949 | 97,278,032 | 86,187,328 | 71,078,511 | 71,021,855 | 70,559,183 | 67,672,303 | 67,420,338 | 54,865,553 | 54,540,715 | 54,532,171 | 45,091,215 | 45,089,537 | 39,576,047 |
Flux de trésorerie 9
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $7M | $7M | $6M | $6M | $7M | $7M | $5M | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $3M | $3M | |
| Operating Cash Flow | $-32M | $-32M | $-22M | $-25M | $-31M | $-33M | $-28M | $-29M | $-26M | $-30M | $-24M | $-20M | $-21M | $-21M | $-15M | $-19M | |
| CapEx | $356.0K | $2.0K | $227.0K | $35.0K | $63.0K | $387.0K | $219.0K | $418.0K | $333.0K | $218.0K | $57.0K | $77.0K | $405.0K | $310.0K | $287.0K | $401.0K | |
| Investing Cash Flow | $12M | $-18M | $17M | $-111M | $-77M | $22M | $43M | $23M | $18M | $-62M | $21M | $-58M | $-19M | $13M | $28M | $-685.0K | |
| Stock Issued | $0 | $61M | $0 | $110M | $134M | $0 | $0 | $0 | $0 | $125M | $0 | $226.0K | $85M | $0 | $25M | $-354.0K | |
| Net Stock Activity | · | $61M | · | · | · | $0 | · | · | · | $125M | · | · | · | · | · | · | |
| Financing Cash Flow | $828.0K | $61M | $2M | $109M | $134M | $11.0K | $575.0K | $126.0K | $816.0K | $125M | $453.0K | $31.0K | $85M | $0 | $25M | $1.0K | |
| Net Change in Cash | $-19M | $11M | $-4M | $-26M | $27M | $-10M | $15M | $-6M | $-7M | $33M | $-3M | $-77M | $45M | $-8M | $38M | $-20M | |
| Free Cash Flow | · | $-32M | · | · | · | $-33M | · | · | · | $-30M | · | · | · | $-21M | · | · |
Rentabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -11.0% | -10.5% | · | -8.9% | -10.8% | -10.1% | · | -12.0% | -10.3% | -8.7% | · | -10.0% | -8.3% | -9.6% | · | -9.0% | |
| ROE | -11.8% | -11.3% | · | -9.6% | -11.6% | -10.9% | · | -13.3% | -11.2% | -9.4% | · | -11.0% | -9.1% | -10.5% | · | -9.8% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 13.2 | 16.3 | · | 14.6 | 16.1 | 12.0 | · | 13.2 | 15.1 | 21.3 | · | 12.3 | 18.5 | 13.0 | · | 15.0 | |
| Quick Ratio | 1.8 | 3.2 | · | 2.5 | 4.2 | 2.8 | · | 2.1 | 2.6 | 3.7 | · | 1.4 | 7.1 | 4.0 | · | 2.2 |
Valorisation (TTM) 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-146M | $-135M | · | $-134M | $-133M | $-122M | · | $-117M | $-105M | $-97M | · | $-97M | $-92M | $-92M | · | $-87M | |
| Market Cap | $1.12B | $1.31B | · | $1.17B | $875M | $397M | · | $723M | $478M | $927M | · | $330M | $423M | $257M | · | $127M | |
| P/E | -7.1 | -8.1 | · | -7.0 | -5.5 | -3.2 | · | -5.9 | -4.0 | -7.5 | · | -2.9 | -3.6 | -2.5 | · | -1.5 | |
| P/B | 2.9 | 3.2 | · | 2.9 | 2.7 | 1.8 | · | 2.6 | 1.6 | 2.8 | · | 1.3 | 1.6 | 1.3 | · | 0.6 | |
| P / Tangible Book | 2.9 | 3.2 | · | 2.9 | 2.7 | 1.8 | · | 2.6 | 1.6 | 2.8 | · | 1.3 | 1.6 | 1.3 | · | 0.6 | |
| P / Cash Flow | · | -40.4 | · | · | · | -12.2 | · | · | · | -30.7 | · | · | · | -12.5 | · | · | |
| P / FCF | · | -40.4 | · | · | · | -12.0 | · | · | · | -30.5 | · | · | · | -12.3 | · | · | |
| Earnings Yield | -14.0% | -12.3% | · | -14.2% | -18.0% | -31.0% | · | -17.1% | -24.9% | -13.4% | · | -34.7% | -28.0% | -39.6% | · | -68.8% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Résultat net | $-129M | $-128M | $-101M | $-89M | $-79M |
| BPA dilué | $-1.47 | $-1.83 | $-1.96 | $-2.25 | $-2.07 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 14.1 | 10.6 | 10.4 | 13.7 | 15.9 |
| Ratio de liquidité réduite | 2.2 | 2.4 | 1.1 | 4.3 | 14.9 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-112M | $-114M | $-87M | $-77M | $-60M |
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Détenteurs institutionnels (13F) 192 déclarants · $1.1B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 40 (-3 vs T. préc.) | 29 (+11 vs T. préc.) | 68 (+17 vs T. préc.) | 44 (-18 vs T. préc.) | +5.7M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Nextech Invest Ltd. | $77 571 359 | 7 162 637 | 6,91% | Actions |
| EcoR1 Capital, LLC | $72 865 496 | 6 728 116 | 6,49% | Actions |
| VIKING GLOBAL INVESTORS LP | $55 522 832 | 5 126 762 | 4,95% | Actions |
| STATE STREET CORP | $53 002 020 | 4 894 000 | 4,72% | Actions |
| SR One Capital Management, LP | $49 984 609 | 4 615 384 | 4,45% | Actions |
| Venrock Adviser, LLC | $46 783 055 | 4 319 765 | 4,17% | Actions |
| NEA Management Company, LLC | $44 604 665 | 4 118 621 | 3,97% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $42 791 160 | 3 951 169 | 3,81% | Actions |
| Nextech Invest Ltd. | $42 655 712 | 5 285 714 | 3,80% | Actions |
| AIHC Capital Management Ltd | $41 462 222 | 3 828 460 | 3,69% | Actions |
| Column Group LLC | $38 346 615 | 3 540 777 | 3,42% | Actions |
| ALKEON CAPITAL MANAGEMENT LLC | $33 845 158 | 3 125 130 | 3,01% | Actions |
| VANGUARD GROUP INC | $32 441 356 | 3 965 936 | 2,89% | Actions |
| CITADEL ADVISORS LLC | $23 789 416 | 2 196 622 | 2,12% | Actions |
| First Turn Management, LLC | $21 847 186 | 2 017 284 | 1,95% | Actions |
| ORBIMED ADVISORS LLC | $21 822 450 | 2 015 000 | 1,94% | Actions |
| Integral Health Asset Management, LLC | $20 577 000 | 1 900 000 | 1,83% | Actions |
| MPM BIOIMPACT LLC | $20 383 814 | 1 882 162 | 1,82% | Actions |
| Vivo Capital, LLC | $20 022 352 | 1 848 786 | 1,78% | Actions |
| GOLDMAN SACHS GROUP INC | $19 593 582 | 1 809 195 | 1,75% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $19 414 443 | 1 792 258 | 1,73% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $18 476 857 | 1 706 081 | 1,65% | Actions |
| FMR LLC | $14 205 494 | 1 311 680 | 1,27% | Actions |
| Woodline Partners LP | $13 510 587 | 1 247 515 | 1,20% | Actions |
| ALGERT GLOBAL LLC | $13 161 623 | 1 215 293 | 1,17% | Actions |
| BRAIDWELL LP | $13 153 468 | 1 214 540 | 1,17% | Actions |
| Candriam S.C.A. | $12 764 594 | 1 179 768 | 1,14% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11 392 109 | 1 051 903 | 1,01% | Actions |
| Defilade Capital Management, L.P. | $11 346 483 | 1 047 690 | 1,01% | Actions |
| Siren, L.L.C. | $10 912 037 | 1 007 575 | 0,97% | Actions |
| Euclidean Capital LLC | $10 715 310 | 989 410 | 0,95% | Actions |
| ROYCE & ASSOCIATES LP | $10 609 761 | 979 664 | 0,94% | Actions |
| EVENTIDE ASSET MANAGEMENT, LLC | $10 337 886 | 954 768 | 0,92% | Actions |
| Qube Research & Technologies Ltd | $8 604 890 | 794 542 | 0,77% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $8 154 806 | 752 983 | 0,73% | Actions |
| Jones Hill Capital LP | $8 093 400 | 747 313 | 0,72% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $8 001 995 | 738 873 | 0,71% | Actions |
| NEXTBio Capital Management LP | $7 647 323 | 706 124 | 0,68% | Actions |
| MILLENNIUM MANAGEMENT LLC | $7 556 026 | 697 694 | 0,67% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7 340 823 | 677 823 | 0,65% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $6 808 626 | 628 682 | 0,61% | Actions |
| TWO SIGMA INVESTMENTS, LP | $6 537 681 | 603 664 | 0,58% | Actions |
| ArrowMark Colorado Holdings LLC | $6 312 536 | 582 875 | 0,56% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $6 130 192 | 566 038 | 0,55% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $5 614 922 | 518 460 | 0,50% | Actions |
| SUPERSTRING CAPITAL MANAGEMENT LP | $4 397 814 | 406 077 | 0,39% | Actions |
| Blue Owl Capital Holdings LP | $4 332 000 | 400 000 | 0,39% | Actions |
| VICTORY CAPITAL MANAGEMENT INC | $4 256 948 | 393 070 | 0,38% | Actions |
| Redmile Group, LLC | $3 920 568 | 362 010 | 0,35% | Actions |
| Boxer Capital Management, LLC | $3 790 500 | 350 000 | 0,34% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $3 736 762 | 345 038 | 0,33% | Actions |
| Squarepoint Ops LLC | $3 729 235 | 344 343 | 0,33% | Actions |
| Pfizer Inc | $3 553 775 | 372 904 | 0,32% | Actions |
| TD Asset Management Inc | $2 664 202 | 246 002 | 0,24% | Actions |
| CITIGROUP INC | $2 647 339 | 244 445 | 0,24% | Actions |
| BANK OF AMERICA CORP /DE/ | $2 638 892 | 243 665 | 0,24% | Actions |
| Trexquant Investment LP | $2 402 300 | 221 819 | 0,21% | Actions |
| XTX Topco Ltd | $2 359 066 | 217 827 | 0,21% | Actions |
| UBS Group AG | $2 266 578 | 209 287 | 0,20% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 935 321 | 178 700 | 0,17% | Option d'achat |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 886 824 | 174 222 | 0,17% | Actions |
| AMERICAN CENTURY COMPANIES INC | $1 826 241 | 168 628 | 0,16% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 508 251 | 139 266 | 0,13% | Actions |
| Jump Financial, LLC | $1 423 062 | 131 400 | 0,13% | Actions |
| Atom Investors LP | $1 408 756 | 130 079 | 0,13% | Actions |
| Ishara Investments LP | $1 332 090 | 123 000 | 0,12% | Actions |
| Caption Management, LLC | $1 191 300 | 110 000 | 0,11% | Option d'achat |
| SPHERA FUNDS MANAGEMENT LTD. | $1 083 000 | 100 000 | 0,10% | Option d'achat |
| Caption Management, LLC | $1 083 000 | 100 000 | 0,10% | Option de vente |
| RHUMBLINE ADVISERS | $1 017 131 | 93 919 | 0,09% | Actions |
| Rafferty Asset Management, LLC | $982 963 | 90 763 | 0,09% | Actions |
| Abu Dhabi Investment Council Co P.J.S.C | $968 646 | 89 441 | 0,09% | Actions |
| Bank of New York Mellon Corp | $965 776 | 89 176 | 0,09% | Actions |
| Swiss National Bank | $933 546 | 86 200 | 0,08% | Actions |
| WINTON GROUP Ltd | $898 890 | 83 000 | 0,08% | Actions |
| BlackRock, Inc. | $864 407 | 79 816 | 0,08% | Actions |
| ALLIANCEBERNSTEIN L.P. | $808 473 | 63 810 | 0,07% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $745 169 | 68 806 | 0,07% | Actions |
| WELLS FARGO & COMPANY/MN | $696 228 | 64 287 | 0,06% | Actions |
| Engineers Gate Manager LP | $693 683 | 64 052 | 0,06% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $612 835 | 48 369 | 0,05% | Actions |
| Caption Management, LLC | $521 248 | 48 130 | 0,05% | Actions |
| PROFUND ADVISORS LLC | $494 931 | 45 700 | 0,04% | Actions |
| MetLife Investment Management, LLC | $474 787 | 43 840 | 0,04% | Actions |
| TUDOR INVESTMENT CORP ET AL | $459 289 | 42 409 | 0,04% | Actions |
| Virtus Investment Advisers, LLC | $428 489 | 39 565 | 0,04% | Actions |
| Optimize Financial Inc | $409 596 | 32 328 | 0,04% | Actions |
| AXQ CAPITAL, LP | $395 501 | 36 519 | 0,04% | Actions |
| Quadrature Capital Ltd | $393 086 | 36 296 | 0,04% | Actions |
| LMR Partners LLP | $381 942 | 35 267 | 0,03% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $372 639 | 34 408 | 0,03% | Actions |
| AlphaQuest LLC | $363 086 | 44 387 | 0,03% | Actions |
| Russell Investments Group, Ltd. | $332 914 | 30 740 | 0,03% | Actions |
| Brevan Howard Capital Management LP | $331 983 | 30 654 | 0,03% | Actions |
| Invesco Ltd. | $318 456 | 29 405 | 0,03% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $310 626 | 28 682 | 0,03% | Actions |
| Vanguard Global Advisers, LLC | $306 457 | 28 297 | 0,03% | Actions |
| D. E. Shaw & Co., Inc. | $287 103 | 26 510 | 0,03% | Actions |
| CITADEL ADVISORS LLC | $281 580 | 26 000 | 0,03% | Option d'achat |
| VANGUARD ASSET MANAGEMENT, Ltd | $272 797 | 25 189 | 0,02% | Actions |
Initiés de la société 11 initiés · 3 dirigeants · 9 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Jacob Chacko | President and CEO | 2 janvier 2024 A | 808 544 | 0 | 0 | $0 |
| Dominic Piscitelli | Chief Financial Officer | 2 janvier 2024 A | 83 809 | 0 | 0 | $0 |
| Pratik S Multani | Chief Medical Officer | 2 janvier 2024 A | 23 809 | 0 | 0 | $0 |
| Richard A. Heyman | Administrateur | 24 juillet 2026 M | 206 672 | 0 | 3 | $-161 062 |
| Angie You | Administrateur | 14 juin 2023 A | — | 0 | 0 | $0 |
| Mardi Dier | Administrateur | 14 juin 2023 A | — | 0 | 0 | $0 |
| Lori Anne Kunkel | Administrateur | 14 juin 2023 A | — | 0 | 0 | $0 |
| Steven L. Hoerter | Administrateur | 14 juin 2023 A | — | 0 | 0 | $0 |
| Peter Svennilson | Administrateur | 16 juin 2021 A | 4 768 181 | 0 | 0 | $0 |
| GORDON CARL L | Administrateur | 16 juin 2021 A | 2 212 571 | 0 | 0 | $0 |
| Richard H Scheller | Administrateur | 24 mai 2021 S | 39 092 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 2 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| SR One Capital Management, LLC, SR One Capital Opportunities Fund I, LP, SR One Capital Opportunities Partners I, LP, AMZL, LP, SR One Capital SMA Partners, LP, SR One Capital Fund II Aggregator, LP, SR One Capital Partners II, LP, Simeon George ×2 dépôts | 14 août 2025 | 4,75% | Amendement | — | SEC |
| OrbiMed Advisors LLC, OrbiMed Capital GP VI LLC, OrbiMed Capital LLC ×5 dépôts | 27 décembre 2022 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 43 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0,78% | 29 424 NS | 30 avril 2026 | N-PORT |
| CANC · Tema ETF Trust | 0,28% | 57 977 NS | 31 mai 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,24% | 124 292 NS | 30 avril 2026 | N-PORT |
| ESSC · Strategy Shares | 0,08% | 2 136 NS | 30 avril 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,04% | 146 225 NS | 31 mai 2026 | N-PORT |
| BIB · ProShares Trust | 0,04% | 3 711 NS | 31 mai 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,02% | 327 184 NS | 30 avril 2026 | N-PORT |
| RSSL · Global X Funds | 0,02% | 28 629 NS | 30 avril 2026 | N-PORT |
| ITWO · ProShares Trust | 0,01% | 3 114 NS | 31 mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 365 890 NS | 31 mai 2026 | N-PORT |
| UWM · ProShares Trust | 0,01% | 2 435 NS | 31 mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 20 039 NS | 30 avril 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 2 463 NS | 31 mai 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,01% | 2 102 NS | 30 avril 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 9 920 NS | 30 avril 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 40 897 NS | 31 mai 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 2 346 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 30 514 NS | 30 avril 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 62 NS | 31 mai 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 97 392 NS | 30 avril 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 46 809 NS | 31 mai 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 11 258 NS | 30 avril 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 7 147 NS | 31 mai 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTI · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWV · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| ITOT · iShares Trust | — | — | 5 août 2026 | Quotidien |
| IWV · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWN · iShares Trust | — | — | 17 août 2026 | Quotidien |
| IWO · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWM · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IBB · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWC · iShares Trust | — | — | 18 août 2026 | Quotidien |
| PRFZ · Invesco Exchange-Traded Fund Trust | — | — | 13 juillet 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | — | — | 20 juillet 2026 | Quotidien |
| ISCB · iShares Trust | — | — | 5 août 2026 | Quotidien |
| ISCG · iShares Trust | — | — | 5 août 2026 | Quotidien |
| ISCV · iShares Trust | — | — | 5 août 2026 | Quotidien |
| WSML · iShares Trust | — | — | 5 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | — | — | 20 juillet 2026 | Quotidien |