STOK Stoke Therapeutics, Inc. - Common Stock
STOK Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
STOK Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
STOK Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 8 42,1%
- Achat 10 52,6%
- Conserver 1 5,3%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
12 analystes · 2026-08-15Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.93 | $-0.81 | -0.12% |
| 31 mars 2026 | $-0.79 | $-0.84 | 0.05% |
| 31 décembre 2025 | $-0.97 | $-0.73 | -0.24% |
| 30 septembre 2025 | $-0.65 | $-0.58 | -0.07% |
| 30 juin 2025 | $-0.40 | $-0.52 | 0.12% |
| 31 mars 2025 | $1.98 | $-0.43 | 2.4% |
| 31 décembre 2024 | $-0.18 | $-0.54 | 0.36% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| STOK | $1.87B | -264.5 | 404.5% | -3.7% | -2.0% | — |
| BHVN | $1.50B | -1.6 | — | — | -310.8% | — |
| ADMA | $4.34B | 30.4 | 19.6% | 28.8% | 33.6% | 57.4% |
| VRDN | $3.17B | -7.7 | 23359.9% | -483.6% | -55.4% | — |
| ZBIO | $1.98B | -4.3 | 100.0% | -3777.4% | -156.8% | — |
| AGIO | $1.59B | -3.8 | 48.0% | -764.0% | -32.2% | — |
| TSHA | $1.57B | -16.2 | 17.3% | -1115.3% | -44.0% | — |
| GENB | — | — | — | — | — | — |
| DMRA | — | — | 38.3% | -17981.1% | -167.0% | — |
| SRPT | $2.26B | -3.0 | 15.6% | -32.5% | -57.1% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 15
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue | $184M | $37M | $9M | $12M | |
| R&D Expense | $138M | $89M | $82M | $78M | |
| SG&A Expense | $67M | $49M | $41M | $39M | |
| Operating Expenses | $205M | $138M | $124M | $117M | |
| Operating Income | $-21M | $-101M | $-115M | $-104M | |
| Interest Expense | $9.0K | $26.0K | $49.0K | · | |
| Interest Income | $14M | $13M | $10M | · | |
| Other Non-op | $-51.0K | $-247.0K | $166.0K | $167.0K | |
| Income Tax | $0 | · | · | · | |
| Net Income | $-7M | $-89M | $-105M | $-101M | |
| EPS (Basic) | $-0.12 | $-1.65 | $-2.38 | $-2.60 | |
| EPS (Diluted) | $-0.12 | $-1.65 | $-2.38 | $-2.60 | |
| Shares (Basic) | 59,219,184 | 54,008,883 | 43,994,862 | 38,897,442 | |
| Shares (Diluted) | 59,219,184 | 54,008,883 | 43,994,862 | 38,897,442 | |
| EBITDA | $-21M | $-101M | $-115M | $-104M |
Bilan 21
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $84M | $128M | $191M | $114M | |
| Receivables | $6M | $2M | · | · | |
| Prepaid Expense | $9M | $11M | $11M | $11M | |
| Other Current Assets | $4M | $2M | $3M | $3M | |
| Current Assets | $306M | $233M | $215M | $244M | |
| PP&E (Net) | $3M | $4M | $6M | $7M | |
| PP&E (Gross) | $13M | $13M | $12M | $11M | |
| Accum. Depreciation | $10M | $9M | $7M | $4M | |
| Total Assets | $418M | $272M | $228M | $256M | |
| Accounts Payable | $5M | $2M | $2M | $766.0K | |
| Current Liabilities | $58M | $40M | $31M | $31M | |
| Capital Leases | $1M | $2M | $5M | $3M | |
| Other Non-current Liabilities | $1M | $2M | $5M | $3M | |
| Total Liabilities | $66M | $43M | $69M | $71M | |
| Common Stock | $5.0K | $5.0K | $5.0K | $4.0K | |
| Paid-in Capital | $850M | $720M | $561M | $483M | |
| Retained Earnings | $-498M | $-491M | $-402M | $-297M | |
| AOCI | $543.0K | $-151.0K | $-24.0K | $-1M | |
| Stockholders' Equity | $352M | $229M | $160M | $185M | |
| Liabilities + Equity | $418M | $272M | $228M | $256M | |
| Shares Outstanding | 58,921,999 | 54,032,826 | 45,918,233 | 39,439,575 |
Flux de trésorerie 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $32M | $27M | $25M | $23M | |
| Operating Cash Flow | $46M | $-87M | $-81M | $-32M | |
| CapEx | $670.0K | $203.0K | $2M | $4M | |
| Investing Cash Flow | $-187M | $-107M | $106M | $-46M | |
| Financing Cash Flow | $97M | $131M | $53M | $46M | |
| Net Change in Cash | $-44M | $-63M | $78M | $-31M | |
| Taxes Paid | $573.0K | · | · | · | |
| Free Cash Flow | $45M | $-87M | $-83M | $-36M |
Rentabilité 5
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Operating Margin | -11.2% | -277.3% | -1307.2% | -841.2% | |
| Net Margin | -3.7% | -243.4% | -1192.5% | -814.7% | |
| EBITDA Margin | -11.2% | -277.3% | -1307.2% | -841.2% | |
| ROA | -2.0% | -35.6% | -43.2% | -40.8% | |
| ROE | -2.0% | -38.6% | -63.0% | -52.0% |
Liquidité et Solvabilité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 5.3 | 5.8 | 7.0 | 7.8 | |
| Quick Ratio | 1.6 | 3.2 | 6.2 | 3.6 | |
| Interest Coverage | -2287.8 | -3898.9 | · | · |
Efficacité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Asset Turnover | 0.5 | 0.1 | 0.0 | 0.1 | |
| Receivables Turnover | 48.5 | · | · | · |
Taux de croissance 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue YoY | 404.5% | 316.3% | -29.2% | · | |
| Revenue CAGR 3Y | 145.9% | · | · | · |
Valorisation (TTM) 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Revenue TTM | $184M | $37M | $9M | $12M | |
| Net Income TTM | $-7M | $-89M | $-105M | $-101M | |
| Market Cap | $1.87B | $596M | $242M | $364M | |
| P/E | -264.5 | -6.7 | -2.2 | -3.5 | |
| P/S | 10.1 | 16.3 | 27.5 | 29.3 | |
| P/B | 5.3 | 2.6 | 1.5 | 2.0 | |
| P / Tangible Book | 5.3 | 2.6 | 1.5 | 2.0 | |
| P / Cash Flow | 41.0 | -6.9 | -3.0 | -11.4 | |
| P / FCF | 41.6 | -6.8 | -2.9 | -10.2 | |
| Earnings Yield | -0.38% | -15.0% | -45.2% | -28.2% |
Compte de résultat 16
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $9M | $6M | $1M | $11M | $14M | $159M | $23M | $5M | $5M | $4M | $3M | $3M | $-2M | $5M | $3M | $3M | |
| R&D Expense | $50M | $40M | $42M | $38M | $26M | $33M | $23M | $22M | $21M | $22M | $22M | $20M | $21M | $20M | $21M | $20M | |
| SG&A Expense | $25M | $20M | $21M | $16M | $15M | $15M | $13M | $13M | $13M | $10M | $11M | $10M | $10M | $10M | $9M | $10M | |
| Operating Expenses | $75M | $60M | $63M | $54M | $41M | $47M | $36M | $35M | $34M | $33M | $32M | $31M | $31M | $30M | $30M | $30M | |
| Operating Income | $-65M | $-53M | $-61M | $-43M | $-27M | $111M | $-14M | $-30M | $-29M | $-28M | $-30M | $-27M | $-33M | $-25M | $-27M | $-27M | |
| Interest Expense | $17.0K | $23.0K | $2.0K | $3.0K | $3.0K | $1.0K | $-1.0K | $0 | $5.0K | $22.0K | · | · | · | · | · | · | |
| Interest Income | $4M | $3M | $4M | $3M | $4M | $3M | $3M | $4M | $4M | $2M | · | · | · | · | · | · | |
| Other Non-op | $308.0K | $18.0K | $-110.0K | $3.0K | $28.0K | $28.0K | $201.0K | $28.0K | $-48.0K | $-428.0K | $42.0K | $41.0K | $41.0K | $42.0K | $41.0K | $42.0K | |
| Pretax Income | $-62M | $-50M | · | $-40M | $-23M | $114M | · | $-26M | $-26M | $-26M | · | · | · | · | · | · | |
| Income Tax | $0 | $0 | $0 | $-1M | $0 | $1M | · | $0 | $0 | $0 | · | $0 | $0 | $0 | · | $0 | |
| Net Income | $-62M | $-50M | $-58M | $-38M | $-23M | $113M | $-10M | $-26M | $-26M | $-26M | $-27M | $-25M | $-31M | $-23M | $-26M | $-26M | |
| EPS (Basic) | $-0.93 | $-0.79 | $-1.02 | $-0.65 | $-0.40 | $1.95 | $-0.15 | $-0.47 | $-0.46 | $-0.57 | $-0.61 | $-0.55 | $-0.69 | $-0.53 | $-0.65 | $-0.66 | |
| EPS (Diluted) | $-0.93 | $-0.79 | $-0.97 | $-0.65 | $-0.40 | $1.90 | $-0.15 | $-0.47 | $-0.46 | $-0.57 | $-0.61 | $-0.55 | $-0.69 | $-0.53 | $-0.65 | $-0.66 | |
| Shares (Basic) | 66,017,895 | 63,063,507 | -115,609,022 | 58,611,677 | 58,353,855 | 57,862,674 | -104,345,028 | 56,341,074 | 55,765,948 | 46,246,889 | -86,996,093 | 44,266,017 | 44,188,464 | 42,536,474 | -77,229,527 | 39,420,310 | |
| Shares (Diluted) | 66,017,895 | 63,063,507 | -117,144,948 | 58,611,677 | 58,353,855 | 59,398,600 | -104,345,028 | 56,341,074 | 55,765,948 | 46,246,889 | -86,996,093 | 44,266,017 | 44,188,464 | 42,536,474 | -77,229,527 | 39,420,310 | |
| EBITDA | $-65M | $-53M | · | $-43M | $-27M | $111M | · | $-30M | $-29M | $-28M | · | $-27M | $-33M | $-25M | · | $-27M |
Bilan 21
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $110M | $156M | $84M | $83M | $101M | $275M | $128M | $150M | $193M | $179M | $191M | $190M | $192M | $190M | $114M | $113M | |
| Receivables | $7M | $4M | $6M | $9M | · | · | $2M | · | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $15M | $10M | $9M | $8M | $14M | $13M | $11M | $10M | $10M | $11M | $11M | $11M | $11M | $10M | $11M | $13M | |
| Other Current Assets | $6M | $7M | $4M | $6M | $7M | $5M | $2M | $4M | $4M | $4M | $3M | $4M | $4M | $6M | $3M | · | |
| Current Assets | $323M | $367M | $306M | $272M | $270M | $376M | $233M | $254M | $297M | $193M | $215M | $230M | $246M | $270M | $244M | $265M | |
| PP&E (Net) | $5M | $3M | $3M | $3M | $3M | $4M | $4M | $4M | $5M | $5M | $6M | $6M | $6M | $7M | $7M | $7M | |
| PP&E (Gross) | · | · | $13M | · | · | · | $13M | · | · | · | $12M | · | · | · | $11M | · | |
| Accum. Depreciation | · | · | $10M | · | · | · | $9M | · | · | · | $7M | · | · | · | $4M | · | |
| Total Assets | $394M | $443M | $418M | $360M | $385M | $407M | $272M | $293M | $308M | $205M | $228M | $240M | $257M | $282M | $256M | $278M | |
| Accounts Payable | $5M | $7M | $5M | $6M | $4M | $2M | $2M | $2M | $4M | $2M | $2M | $3M | $2M | $4M | $766.0K | $2M | |
| Current Liabilities | $42M | $41M | $58M | $42M | $39M | $45M | $40M | $50M | $44M | $36M | $31M | $25M | $22M | $32M | $31M | $29M | |
| Capital Leases | $837.0K | $990.0K | $1M | $2M | $1M | $2M | $2M | $3M | $4M | $4M | $5M | $819.0K | $1M | $2M | $3M | $3M | |
| Other Non-current Liabilities | $837.0K | $991.0K | $1M | $2M | $1M | $2M | $2M | $3M | $4M | $4M | $5M | $959.0K | $2M | $2M | $3M | $4M | |
| Total Liabilities | $48M | $48M | $66M | $52M | $50M | $57M | $43M | $61M | $65M | $65M | $69M | $67M | $67M | $68M | $71M | $73M | |
| Common Stock | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Paid-in Capital | $955M | $943M | $850M | $747M | $736M | $728M | $720M | $712M | $697M | $569M | $561M | $548M | $541M | $534M | $483M | $477M | |
| Retained Earnings | $-609M | $-548M | $-498M | $-440M | $-401M | $-378M | $-491M | $-480M | $-454M | $-428M | $-402M | $-375M | $-350M | $-320M | $-297M | $-271M | |
| AOCI | $-542.0K | $-115.0K | $543.0K | $446.0K | $96.0K | $-104.0K | $-151.0K | $166.0K | $-15.0K | · | $-24.0K | $-147.0K | $-379.0K | $-598.0K | $-1M | $-2M | |
| Stockholders' Equity | $346M | $395M | $352M | $308M | $335M | $350M | $229M | $232M | $243M | $140M | $160M | $173M | $190M | $214M | $185M | $204M | |
| Liabilities + Equity | $394M | $443M | $418M | $360M | $385M | $407M | $272M | $293M | $308M | $205M | $228M | $240M | $257M | $282M | $256M | $278M | |
| Shares Outstanding | 62,402,595 | 62,240,347 | 58,921,999 | 55,120,002 | 54,723,455 | 54,595,714 | 54,032,826 | 52,941,191 | 52,305,641 | 46,498,077 | 45,918,233 | 44,293,115 | 44,202,997 | 44,175,089 | 39,439,575 | 39,426,440 |
Flux de trésorerie 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $11M | $9M | $10M | $8M | $8M | $7M | $7M | $7M | $7M | $5M | $6M | $7M | $7M | $6M | $6M | $6M | |
| Operating Cash Flow | $-57M | $-61M | $-30M | $-30M | $-25M | $132M | $-23M | $-22M | $-17M | $-25M | $-21M | $-17M | $-22M | $-21M | $-22M | $-22M | |
| CapEx | $2M | $353.0K | $232.0K | $132.0K | $154.0K | $152.0K | $42.0K | $103.0K | $46.0K | $12.0K | $229.0K | $383.0K | $839.0K | $165.0K | $409.0K | $2M | |
| Investing Cash Flow | $9M | $51M | $-61M | $9M | $-148M | $14M | $819.0K | $-30M | $-88M | $10M | $15M | $15M | $23M | $53M | $22M | $67M | |
| Financing Cash Flow | $2M | $84M | $92M | $3M | $554.0K | $1M | $568.0K | $8M | $121M | $2M | $7M | $562.0K | $48.0K | $45M | $43.0K | $434.0K | |
| Net Change in Cash | $-46M | $74M | $826.0K | $-18M | $-173M | $147M | $-22M | $-43M | $15M | $-13M | $1M | $-2M | $2M | $77M | $160.0K | $46M | |
| Free Cash Flow | · | $-61M | · | · | · | $132M | · | · | · | $-25M | · | · | · | $-22M | · | · | |
| Levered FCF | · | $-61M | · | · | · | $132M | · | · | · | · | · | · | · | · | · | · |
Rentabilité 7
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -701.6% | -857.6% | · | -405.3% | -197.6% | 70.2% | · | -613.1% | -607.4% | -673.0% | · | -823.3% | 1340.7% | -479.2% | · | -934.5% | |
| Net Margin | -660.8% | -802.8% | · | -360.7% | -170.0% | 71.2% | · | -540.0% | -531.9% | -625.6% | · | -741.9% | 1235.5% | -437.6% | · | -898.8% | |
| Pretax Margin | -660.8% | -802.8% | · | -372.7% | -170.0% | 72.0% | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -701.6% | -857.6% | · | -405.3% | -197.6% | 70.2% | · | -613.1% | -607.4% | -673.0% | · | -823.3% | 1340.7% | -479.2% | · | -934.5% | |
| ROA | -15.8% | -11.8% | · | -11.7% | -6.8% | 36.9% | · | -9.9% | -9.1% | -10.8% | · | -9.5% | -11.0% | -7.5% | · | -9.8% | |
| ROE | -18.1% | -13.4% | · | -14.2% | -8.1% | 46.0% | · | -13.1% | -11.9% | -14.9% | · | -13.0% | -14.8% | -9.9% | · | -11.8% | |
| ROIC | -18.9% | -13.5% | · | -13.5% | -8.2% | 31.4% | · | · | · | · | · | · | · | · | · | · |
Liquidité et Solvabilité 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.7 | 9.0 | · | 6.5 | 7.0 | 8.4 | · | 5.1 | 6.7 | 5.4 | · | 9.1 | 11.3 | 8.6 | · | 9.2 | |
| Quick Ratio | 2.8 | 3.9 | · | 2.2 | 2.6 | 6.2 | · | 3.0 | 4.3 | 5.0 | · | 7.5 | 8.8 | 6.0 | · | 3.9 | |
| Interest Coverage | -3848.8 | -2322.5 | · | -14363.7 | -9100.0 | 111240.0 | · | · | · | · | · | · | · | · | · | · |
Efficacité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.5 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | -0.0 | 0.0 | · | 0.0 | |
| Receivables Turnover | 2.6 | 2.8 | · | 2.3 | · | · | · | · | · | · | · | · | · | · | · | · |
Valorisation (TTM) 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $40M | $189M | · | $188M | $182M | $173M | · | $17M | $10M | $10M | · | $9M | $9M | $14M | · | · | |
| Net Income TTM | $-173M | $1M | · | $25M | $37M | $34M | · | $-103M | $-107M | $-104M | · | $-104M | $-104M | $-98M | · | $-98M | |
| Market Cap | $2.04B | $2.03B | · | $1.30B | $621M | $363M | · | $651M | $707M | $628M | · | $175M | $470M | $368M | · | $506M | |
| P/E | -11.8 | 542.7 | · | 61.8 | 19.9 | 16.6 | · | -6.0 | -6.0 | -5.8 | · | -1.6 | -4.2 | -3.4 | · | -5.0 | |
| P/S | 51.0 | 10.7 | · | 6.9 | 3.4 | 2.1 | · | 37.7 | 71.6 | 61.6 | · | 19.6 | 53.4 | 25.8 | · | · | |
| P/B | 5.9 | 5.1 | · | 4.2 | 1.9 | 1.0 | · | 2.8 | 2.9 | 4.5 | · | 1.0 | 2.5 | 1.7 | · | 2.5 | |
| P / Tangible Book | 5.9 | 5.1 | · | 4.2 | 1.9 | 1.0 | · | 2.8 | 2.9 | 4.5 | · | 1.0 | 2.5 | 1.7 | · | 2.5 | |
| P / Cash Flow | · | -33.5 | · | · | · | 2.8 | · | · | · | -25.6 | · | · | · | -17.2 | · | · | |
| P / FCF | · | -33.3 | · | · | · | 2.8 | · | · | · | -25.5 | · | · | · | -17.1 | · | · | |
| Earnings Yield | -8.5% | 0.18% | · | 1.6% | 5.0% | 6.0% | · | -16.7% | -16.8% | -17.3% | · | -61.7% | -23.6% | -29.8% | · | -19.9% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $184M | $37M | $9M | $12M | — |
| Marge d'exploitation % | -11.2% | -277.3% | -1307.2% | -841.2% | — |
| Résultat net | $-7M | $-89M | $-105M | $-101M | $-86M |
| BPA dilué | $-0.12 | $-1.65 | $-2.38 | $-2.60 | $-2.34 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 5.3 | 5.8 | 7.0 | 7.8 | 13.4 |
| Ratio de liquidité réduite | 1.6 | 3.2 | 6.2 | 3.6 | 8.5 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $45M | $-87M | $-83M | $-36M | $-68M |
Dernières actualités Actualités récentes mentionnant cette entreprise
Signaux de trading Signaux d'achat/vente récents avec prix d'entrée et ratio risque/récompense
Mes métriques Votre watchlist personnelle — lignes sélectionnées de Fondamentaux Complets
Choisissez les indicateurs qui vous importent — cliquez sur le ➕ à côté de n'importe quelle ligne dans Fondamentaux Complets ci-dessus.
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Détenteurs institutionnels (13F) 206 déclarants · $2.0B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 37 (-2 vs T. préc.) | 25 (-1 vs T. préc.) | 64 (-8 vs T. préc.) | 57 (-1 vs T. préc.) | +7.1M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| RTW INVESTMENTS, LP | $184 001 738 | 5 623 525 | 9,14% | Actions |
| FMR LLC | $150 968 444 | 4 613 950 | 7,50% | Actions |
| Lynx1 Capital Management LP | $132 136 579 | 4 038 404 | 6,56% | Actions |
| Redmile Group, LLC | $129 110 502 | 3 945 920 | 6,41% | Actions |
| BAKER BROS. ADVISORS LP | $109 176 726 | 3 336 697 | 5,42% | Actions |
| TORONTO DOMINION BANK | $103 829 002 | 3 173 258 | 5,16% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $97 499 612 | 2 979 817 | 4,84% | Actions |
| STATE STREET CORP | $93 325 293 | 2 852 240 | 4,63% | Actions |
| VANGUARD GROUP INC | $86 966 267 | 2 739 958 | 4,32% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $84 644 579 | 2 586 937 | 4,20% | Actions |
| BVF INC/IL | $83 356 065 | 2 547 557 | 4,14% | Actions |
| Siren, L.L.C. | $65 287 754 | 1 995 347 | 3,24% | Actions |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $59 664 920 | 1 823 500 | 2,96% | Actions |
| Skorpios Trust | $53 020 254 | 2 256 181 | 2,63% | Actions |
| JANUS HENDERSON GROUP PLC | $51 840 980 | 1 593 881 | 2,57% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $43 134 838 | 1 318 037 | 2,14% | Actions |
| Assenagon Asset Management S.A. | $36 920 855 | 1 128 388 | 1,83% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $31 236 868 | 954 672 | 1,55% | Actions |
| Polar Capital Holdings Plc | $27 279 188 | 833 716 | 1,35% | Actions |
| EcoR1 Capital, LLC | $24 049 200 | 735 000 | 1,19% | Actions |
| MPM BIOIMPACT LLC | $23 666 834 | 723 314 | 1,18% | Actions |
| Opaleye Management Inc. | $22 904 000 | 700 000 | 1,14% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $18 552 011 | 566 993 | 0,92% | Actions |
| Troluce Capital Advisors LLC | $16 242 732 | 496 416 | 0,81% | Actions |
| FIRST TRUST ADVISORS LP | $16 062 673 | 490 913 | 0,80% | Actions |
| Candriam S.C.A. | $15 694 935 | 480 136 | 0,78% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $15 280 633 | 467 012 | 0,76% | Actions |
| Granahan Investment Management, LLC | $15 103 814 | 461 608 | 0,75% | Actions |
| Erste Asset Management GmbH | $13 875 261 | 428 381 | 0,69% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $13 169 898 | 402 503 | 0,65% | Actions |
| GOLDMAN SACHS GROUP INC | $12 775 295 | 390 443 | 0,63% | Actions |
| Parkman Healthcare Partners LLC | $11 630 095 | 355 443 | 0,58% | Actions |
| Artisan Partners Limited Partnership | $11 620 606 | 355 153 | 0,58% | Actions |
| TANG CAPITAL MANAGEMENT LLC | $9 816 000 | 300 000 | 0,49% | Actions |
| MILLENNIUM MANAGEMENT LLC | $8 540 836 | 261 028 | 0,42% | Actions |
| CITADEL ADVISORS LLC | $7 719 237 | 235 918 | 0,38% | Actions |
| Birchview Capital, LP | $5 827 759 | 178 110 | 0,29% | Actions |
| NORGES BANK | $5 339 904 | 163 200 | 0,27% | Actions |
| BAILLIE GIFFORD & CO | $4 441 216 | 135 734 | 0,22% | Actions |
| DAFNA Capital Management LLC | $4 282 230 | 130 875 | 0,21% | Actions |
| ExodusPoint Capital Management, LP | $4 242 475 | 129 660 | 0,21% | Actions |
| BANK OF AMERICA CORP /DE/ | $4 226 737 | 129 179 | 0,21% | Actions |
| JANE STREET GROUP, LLC | $3 932 879 | 120 198 | 0,20% | Actions |
| GILDER GAGNON HOWE & CO LLC | $3 699 487 | 113 065 | 0,18% | Actions |
| BlackRock, Inc. | $3 657 180 | 111 772 | 0,18% | Actions |
| Jump Financial, LLC | $3 414 332 | 104 350 | 0,17% | Actions |
| Schonfeld Strategic Advisors LLC | $3 344 932 | 102 229 | 0,17% | Actions |
| JPMORGAN CHASE & CO | $2 800 925 | 83 993 | 0,14% | Actions |
| Palo Alto Investors LP | $2 769 126 | 84 631 | 0,14% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $2 649 273 | 80 968 | 0,13% | Actions |
| XTX Topco Ltd | $2 604 937 | 79 613 | 0,13% | Actions |
| RHUMBLINE ADVISERS | $2 484 451 | 75 931 | 0,12% | Actions |
| Swiss National Bank | $2 427 824 | 74 200 | 0,12% | Actions |
| Trexquant Investment LP | $2 404 102 | 73 475 | 0,12% | Actions |
| TD Asset Management Inc | $2 198 784 | 67 200 | 0,11% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2 164 755 | 66 160 | 0,11% | Actions |
| CITIGROUP INC | $2 164 330 | 66 147 | 0,11% | Actions |
| Rhenman & Partners Asset Management AB | $2 110 440 | 64 500 | 0,10% | Actions |
| ALPS ADVISORS INC | $2 061 687 | 63 010 | 0,10% | Actions |
| TWO SIGMA INVESTMENTS, LP | $2 040 779 | 62 371 | 0,10% | Actions |
| ALLIANCEBERNSTEIN L.P. | $2 031 418 | 62 390 | 0,10% | Actions |
| HighVista Strategies LLC | $2 006 260 | 61 316 | 0,10% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 968 664 | 60 167 | 0,10% | Actions |
| PANAGORA ASSET MANAGEMENT INC | $1 925 343 | 58 843 | 0,10% | Actions |
| Bank of New York Mellon Corp | $1 903 453 | 58 174 | 0,09% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1 680 291 | 51 606 | 0,08% | Actions |
| Woodline Partners LP | $1 639 926 | 50 120 | 0,08% | Actions |
| Quantinno Capital Management LP | $1 633 644 | 49 928 | 0,08% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $1 623 272 | 49 611 | 0,08% | Actions |
| Moran Wealth Management, LLC | $1 569 807 | 47 977 | 0,08% | Actions |
| VICTORY CAPITAL MANAGEMENT INC | $1 469 128 | 44 900 | 0,07% | Actions |
| Rafferty Asset Management, LLC | $1 431 238 | 43 742 | 0,07% | Actions |
| HUSSMAN STRATEGIC ADVISORS, INC. | $1 374 240 | 42 000 | 0,07% | Actions |
| Quadrature Capital Ltd | $1 348 882 | 41 225 | 0,07% | Actions |
| PLATINUM INVESTMENT MANAGEMENT LTD | $1 335 467 | 40 815 | 0,07% | Actions |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $1 164 766 | 35 598 | 0,06% | Actions |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $1 093 033 | 33 746 | 0,05% | Actions |
| MetLife Investment Management, LLC | $1 051 359 | 32 132 | 0,05% | Actions |
| Corient Private Wealth LP | $1 009 020 | 30 838 | 0,05% | Actions |
| OMERS ADMINISTRATION Corp | $981 600 | 30 000 | 0,05% | Actions |
| Squarepoint Ops LLC | $959 023 | 29 310 | 0,05% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $883 833 | 27 012 | 0,04% | Actions |
| Vanguard Global Advisers, LLC | $871 628 | 26 639 | 0,04% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $821 730 | 25 114 | 0,04% | Actions |
| Cresset Asset Management, LLC | $798 728 | 24 411 | 0,04% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $736 200 | 22 500 | 0,04% | Option d'achat |
| PROFUND ADVISORS LLC | $733 452 | 22 416 | 0,04% | Actions |
| Invesco Ltd. | $719 415 | 21 987 | 0,04% | Actions |
| D. E. Shaw & Co., Inc. | $698 736 | 21 355 | 0,03% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $687 120 | 21 000 | 0,03% | Option de vente |
| LPL Financial LLC | $675 504 | 20 645 | 0,03% | Actions |
| AMERIPRISE FINANCIAL INC | $668 240 | 20 423 | 0,03% | Actions |
| Balyasny Asset Management L.P. | $652 404 | 19 939 | 0,03% | Actions |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $558 432 | 17 067 | 0,03% | Actions |
| Police & Firemen's Retirement System of New Jersey | $531 536 | 16 245 | 0,03% | Actions |
| Aquatic Capital Management LLC | $506 211 | 15 471 | 0,03% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $498 587 | 15 238 | 0,02% | Actions |
| AlphaQuest LLC | $477 243 | 15 036 | 0,02% | Actions |
| MORGAN STANLEY | $476 959 | 14 577 | 0,02% | Actions |
| CIM, LLC | $476 272 | 14 556 | 0,02% | Actions |
Initiés de la société 16 initiés · 7 dirigeants · 9 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Ian F Smith | Chief Executive Officer | 17 février 2026 A | — | 0 | 0 | $0 |
| Stephen J Tulipano | CFO | 1 décembre 2023 A | 11 762 | 0 | 0 | $0 |
| Huw M. Nash | COO & CBO | 1 décembre 2023 A | 0 | 0 | 0 | $0 |
| Jonathan Allan | GENERAL COUNSEL & CORP SEC | 14 août 2026 M | 21 225 | 0 | 3 | $-135 284 |
| Barry Ticho | CHIEF MEDICAL OFFICER | 14 août 2026 M | 25 655 | 0 | 7 | $-652 076 |
| Thomas Mccauley | Chief Scientific Officer | 15 juillet 2026 A | — | 0 | 0 | $0 |
| Gene Liau | EVP Research & Preclinical Dev | 2 mars 2021 M | 21 351 | 0 | 0 | $0 |
| Edward M. Kaye MD | Administrateur | 14 août 2026 M | 124 557 | 0 | 2 | $-402 562 |
| Seth Loring Harrison | Administrateur | 16 juillet 2026 G | 17 161 713 | 0 | 0 | $0 |
| Adrian R. Krainer | Administrateur | 3 juin 2026 A | — | 0 | 0 | $0 |
| Jennifer Burstein | Administrateur | 3 juin 2026 A | — | 0 | 0 | $0 |
| Arthur Tzianabos | Administrateur | 3 juin 2026 A | — | 0 | 0 | $0 |
| Julie Smith | Administrateur | 3 juin 2026 A | — | 0 | 0 | $0 |
| LEVIN ARTHUR A | Administrateur | 3 juin 2026 A | 4 237 | 0 | 1 | $-22 264 |
| Garry E Menzel | Administrateur | 13 juin 2023 A | — | 0 | 0 | $0 |
| Robin A. Walker | — | 7 juillet 2020 S | 0 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 4 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Blue Horizon Enterprise Ltd, Ezbon International Ltd, Montrago Trustees Ltd, Skorpios Trust ×3 dépôts | 26 août 2025 | 4,10% | Amendement | — | SEC |
| Blue Horizon Enterprise Ltd., Ezbon International Limited, Montrago Trustees Limited, Skorpios Trust ×4 dépôts | 27 décembre 2024 | 13,00% | Amendement | — | SEC |
| ATP Life Science Ventures, L.P., formerly known as Apple Tree Partners IV, L.P., ATP III GP, Ltd., Seth L. Harrison | 29 juin 2021 | — | Dépôt initial | — | SEC |
| Apple Tree Partners IV, L.P., ATP III GP, Ltd., Seth L. Harrison ×2 dépôts | 27 novembre 2020 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 50 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| GNOM · Global X Funds | 1,45% | 26 232 NS | 31 mai 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 1,18% | 15 670 NS | 31 mai 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 1,12% | 58 873 NS | 31 mai 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,75% | 8 521 NS | 30 avril 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,60% | 10 049 NS | 31 mai 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0,56% | 179 037 NS | 30 avril 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,41% | 64 471 NS | 30 avril 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,26% | 100 854 NS | 30 avril 2026 | N-PORT |
| FYX · First Trust Exchange-Traded AlphaDE… | 0,23% | 85 288 NS | 30 avril 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,14% | 3 388 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,12% | 361 674 SH | 8 août 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | 0,12% | 75 065 SH | 8 août 2026 | Quotidien |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,11% | 16 704 NS | 30 avril 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,11% | 59 041 SH | 8 août 2026 | Quotidien |
| IWO · iShares Trust | 0,11% | 496 085 SH | 8 août 2026 | Quotidien |
| FSMD · FIDELITY COVINGTON TRUST | 0,10% | 72 925 NS | 30 avril 2026 | N-PORT |
| BIB · ProShares Trust | 0,09% | 2 111 NS | 31 mai 2026 | N-PORT |
| ESSC · Strategy Shares | 0,08% | 623 NS | 30 avril 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,07% | 6 327 SH | 8 août 2026 | Quotidien |
| GSSC · Goldman Sachs ETF Trust | 0,07% | 22 102 NS | 31 mai 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,06% | 13 588 NS | 30 avril 2026 | N-PORT |
| IWM · iShares Trust | 0,05% | 1 385 028 SH | 8 août 2026 | Quotidien |
| ISCG · iShares Trust | 0,05% | 16 624 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,05% | 317 008 SH | 8 août 2026 | Quotidien |
| RSSL · Global X Funds | 0,05% | 21 239 NS | 30 avril 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,04% | 179 692 NS | 30 avril 2026 | N-PORT |
| ITWO · ProShares Trust | 0,04% | 2 305 NS | 31 mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,03% | 247 558 NS | 31 mai 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,03% | 27 702 SH | 8 août 2026 | Quotidien |
| ISCB · iShares Trust | 0,03% | 2 364 SH | 8 août 2026 | Quotidien |
| UWM · ProShares Trust | 0,02% | 1 803 NS | 31 mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,02% | 18 412 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,02% | 643 361 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,02% | 111 259 SH | 8 août 2026 | Quotidien |
| URTY · ProShares Trust | 0,02% | 1 824 NS | 31 mai 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 2 915 SH | 8 août 2026 | Quotidien |
| DFAC · Dimensional ETF Trust | 0,01% | 127 867 NS | 30 avril 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 1 903 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 46 NS | 31 mai 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 4 751 NS | 30 avril 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 16 308 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 10 507 NS | 30 avril 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 80 160 SH | 8 août 2026 | Quotidien |
| IWV · iShares Trust | 0,00% | 13 581 SH | 8 août 2026 | Quotidien |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 28 492 NS | 31 mai 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 11 068 NS | 30 avril 2026 | N-PORT |
| DFSU · Dimensional ETF Trust | 0,00% | 407 NS | 30 avril 2026 | N-PORT |
| DFUV · Dimensional ETF Trust | 0,00% | 341 NS | 30 avril 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 885 403 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 4 620 SH | 8 août 2026 | Quotidien |