| FMR LLC |
$294502456 |
25410048 |
16.43% |
股份
|
| ARK Investment Management LLC |
$149803896 |
12925271 |
8.36% |
股份
|
| BlackRock, Inc. |
$141111753 |
12175302 |
7.87% |
股份
|
| STATE STREET CORP |
$93847800 |
8097308 |
5.24% |
股份
|
| AMERIPRISE FINANCIAL INC |
$81034560 |
6991763 |
4.52% |
股份
|
| Redmile Group, LLC |
$78112833 |
6739675 |
4.36% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$70961826 |
6122677 |
3.96% |
股份
|
| ADVANCED MICRO DEVICES INC |
$66228563 |
5714285 |
3.70% |
股份
|
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
$66118864 |
5704820 |
3.69% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$63669503 |
5493486 |
3.55% |
股份
|
| D. E. Shaw & Co., Inc. |
$60728749 |
5239754 |
3.39% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$41538252 |
3583163 |
2.32% |
股份
|
| Woodline Partners LP |
$31300823 |
2700675 |
1.75% |
股份
|
| Siren, L.L.C. |
$28682515 |
2474764 |
1.60% |
股份
|
| VANGUARD GROUP INC |
$27606616 |
7910205 |
1.54% |
股份
|
| BVF INC/IL |
$27371802 |
2361674 |
1.53% |
股份
|
| Gem Investment Advisors, LLC |
$25160302 |
2170863 |
1.40% |
股份
|
| BAKER BROS. ADVISORS LP |
$24742367 |
2134803 |
1.38% |
股份
|
| GOLDMAN SACHS GROUP INC |
$20077635 |
1732324 |
1.12% |
股份
|
| Nuveen, LLC |
$19980916 |
1723979 |
1.11% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$19814264 |
1709600 |
1.11% |
买入期权
|
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
$18577796 |
1602916 |
1.04% |
股份
|
| MORGAN STANLEY |
$15932693 |
1374693 |
0.89% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$15519288 |
1339024 |
0.87% |
股份
|
| FRED ALGER MANAGEMENT, LLC |
$13639077 |
1176797 |
0.76% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$13513882 |
1165995 |
0.75% |
股份
|
| UBS Group AG |
$13199202 |
1138844 |
0.74% |
股份
|
| NORTHERN TRUST CORP |
$12885936 |
1111815 |
0.72% |
股份
|
| Sumitomo Mitsui Trust Group, Inc. |
$11889312 |
1025825 |
0.66% |
股份
|
| Amova Asset Management Americas, Inc. |
$11741715 |
1013965 |
0.66% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$11290074 |
974122 |
0.63% |
股份
|
| Casdin Capital, LLC |
$11280083 |
973260 |
0.63% |
股份
|
| Parkman Healthcare Partners LLC |
$10365795 |
894374 |
0.58% |
股份
|
| Integral Health Asset Management, LLC |
$9272000 |
800000 |
0.52% |
股份
|
| LAZARD ASSET MANAGEMENT LLC |
$9059810 |
781692 |
0.51% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$8768309 |
756541 |
0.49% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$6954584 |
600174 |
0.39% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$6559929 |
565999 |
0.37% |
股份
|
| Invesco Ltd. |
$6315773 |
544933 |
0.35% |
股份
|
| GROUP ONE TRADING LLC |
$6081818 |
524747 |
0.34% |
股份
|
| MARSHALL WACE, LLP |
$5822896 |
502407 |
0.32% |
股份
|
| Trexquant Investment LP |
$5581222 |
481555 |
0.31% |
股份
|
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd |
$5546047 |
478520 |
0.31% |
股份
|
| Artia Global Partners LP |
$5382906 |
464444 |
0.30% |
股份
|
| ROYCE & ASSOCIATES LP |
$5166555 |
445777 |
0.29% |
股份
|
| WELLINGTON MANAGEMENT GROUP LLP |
$4694935 |
405085 |
0.26% |
股份
|
| CITADEL ADVISORS LLC |
$4494602 |
387800 |
0.25% |
买入期权
|
| Bank of New York Mellon Corp |
$4483386 |
386832 |
0.25% |
股份
|
| Balyasny Asset Management L.P. |
$4161865 |
359091 |
0.23% |
股份
|
| Ikarian Capital, LLC |
$4100217 |
353772 |
0.23% |
股份
|
| Sofinnova Investments, Inc. |
$3910466 |
337400 |
0.22% |
股份
|
| Schonfeld Strategic Advisors LLC |
$3238152 |
279392 |
0.18% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$2882445 |
248701 |
0.16% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$2829200 |
244107 |
0.16% |
股份
|
| PLATINUM INVESTMENT MANAGEMENT LTD |
$2755685 |
237764 |
0.15% |
股份
|
| Point72 Asset Management, L.P. |
$2641628 |
227923 |
0.15% |
股份
|
| CITIGROUP INC |
$2352817 |
203004 |
0.13% |
股份
|
| ROYAL BANK OF CANADA |
$2322000 |
200339 |
0.13% |
股份
|
| Wilmington Savings Fund Society, FSB |
$2196560 |
189522 |
0.12% |
股份
|
| Palumbo Wealth Management LLC |
$2123207 |
183193 |
0.12% |
股份
|
| RHUMBLINE ADVISERS |
$2067169 |
178359 |
0.12% |
股份
|
| JANE STREET GROUP, LLC |
$1966823 |
169700 |
0.11% |
买入期权
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$1923940 |
166000 |
0.11% |
卖出期权
|
| WELLS FARGO & COMPANY/MN |
$1895498 |
163546 |
0.11% |
股份
|
| Squarepoint Ops LLC |
$1882784 |
162449 |
0.11% |
股份
|
| JPMORGAN CHASE & CO |
$1865214 |
164336 |
0.10% |
股份
|
| Caitong International Asset Management Co., Ltd |
$1823327 |
157319 |
0.10% |
股份
|
| Independent Advisor Alliance |
$1783179 |
153855 |
0.10% |
股份
|
| VICTORY CAPITAL MANAGEMENT INC |
$1756291 |
151535 |
0.10% |
股份
|
| Rafferty Asset Management, LLC |
$1666063 |
143750 |
0.09% |
股份
|
| CERTUITY, LLC |
$1630678 |
140697 |
0.09% |
股份
|
| DEUTSCHE BANK AG\ |
$1590901 |
137265 |
0.09% |
股份
|
| RAYMOND JAMES FINANCIAL INC |
$1568383 |
135322 |
0.09% |
股份
|
| OSAIC HOLDINGS, INC. |
$1516632 |
130878 |
0.08% |
股份
|
| Scientech Research LLC |
$1442190 |
124434 |
0.08% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$1395865 |
120437 |
0.08% |
股份
|
| BOOTHBAY FUND MANAGEMENT, LLC |
$1258361 |
108573 |
0.07% |
股份
|
| CITADEL ADVISORS LLC |
$1191174 |
102776 |
0.07% |
股份
|
| Creative Planning |
$1185889 |
102320 |
0.07% |
股份
|
| PEAK6 LLC |
$1159000 |
100000 |
0.06% |
买入期权
|
| Institute for Wealth Management, LLC. |
$1157749 |
99892 |
0.06% |
股份
|
| TWO SIGMA ADVISERS, LP |
$1096907 |
314300 |
0.06% |
股份
|
| XTX Topco Ltd |
$1076920 |
92918 |
0.06% |
股份
|
| SummitTX Capital, L.P. |
$1054829 |
91012 |
0.06% |
股份
|
| Uniting Wealth Partners, LLC |
$1034408 |
89250 |
0.06% |
股份
|
| Man Group plc |
$988314 |
85273 |
0.06% |
股份
|
| FEDERATED HERMES, INC. |
$986726 |
85136 |
0.06% |
股份
|
| MetLife Investment Management, LLC |
$943797 |
81432 |
0.05% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$927956 |
80411 |
0.05% |
股份
|
| KING LUTHER CAPITAL MANAGEMENT CORP |
$898457 |
77520 |
0.05% |
股份
|
| Vanguard Global Advisers, LLC |
$866260 |
74742 |
0.05% |
股份
|
| HENGEHOLD CAPITAL MANAGEMENT LLC |
$854369 |
73716 |
0.05% |
股份
|
| PROFUND ADVISORS LLC |
$843625 |
72789 |
0.05% |
股份
|
| LPL Financial LLC |
$823806 |
71079 |
0.05% |
股份
|
| BARCLAYS PLC |
$788792 |
68058 |
0.04% |
股份
|
| SBI Securities Co., Ltd. |
$787610 |
67956 |
0.04% |
股份
|
| SIMPLEX TRADING, LLC |
$761544 |
65707 |
0.04% |
股份
|
| BARCLAYS PLC |
$711626 |
61400 |
0.04% |
买入期权
|
| GRIFFIN ASSET MANAGEMENT, INC. |
$658416 |
56760 |
0.04% |
股份
|
| ENVESTNET ASSET MANAGEMENT INC |
$645053 |
55656 |
0.04% |
股份
|
| CITADEL ADVISORS LLC |
$608475 |
52500 |
0.03% |
卖出期权
|
| JANE STREET GROUP, LLC |
$585295 |
50500 |
0.03% |
卖出期权
|
| Russell Investments Group, Ltd. |
$533371 |
46020 |
0.03% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$500688 |
43200 |
0.03% |
股份
|
| Brevan Howard Capital Management LP |
$495658 |
42766 |
0.03% |
股份
|
| PIER 88 INVESTMENT PARTNERS LLC |
$492575 |
42500 |
0.03% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$488670 |
162890 |
0.03% |
股份
|
| MH & ASSOCIATES SECURITIES MANAGEMENT CORP /ADV |
$467506 |
40337 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$466324 |
40235 |
0.03% |
股份
|
| WINTON GROUP Ltd |
$445056 |
38400 |
0.02% |
股份
|
| Caption Management, LLC |
$423035 |
36500 |
0.02% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$421749 |
36389 |
0.02% |
股份
|
| Quantinno Capital Management LP |
$419083 |
36159 |
0.02% |
股份
|
| AXQ CAPITAL, LP |
$417240 |
36000 |
0.02% |
股份
|
| China Universal Asset Management Co., Ltd. |
$403471 |
34812 |
0.02% |
股份
|
| Aerodigm Wealth, LLC |
$395886 |
131962 |
0.02% |
股份
|
| Cherry Creek Investment Advisors, Inc. |
$365027 |
31495 |
0.02% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$364184 |
34357 |
0.02% |
股份
|
| Clearstead Advisors, LLC |
$347770 |
30006 |
0.02% |
股份
|
| Gotham Asset Management, LLC |
$340317 |
29363 |
0.02% |
股份
|
| Golden State Wealth Management, LLC |
$324520 |
28000 |
0.02% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$321565 |
27745 |
0.02% |
股份
|
| Mariner, LLC |
$309370 |
26688 |
0.02% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$308375 |
26607 |
0.02% |
股份
|
| LMR Partners LLP |
$304817 |
26300 |
0.02% |
股份
|
| Engineers Gate Manager LP |
$304701 |
26290 |
0.02% |
股份
|
| Jain Global LLC |
$304411 |
26265 |
0.02% |
股份
|
| Wealthfront Advisers LLC |
$303925 |
26223 |
0.02% |
股份
|
| US BANCORP \DE\ |
$302858 |
26131 |
0.02% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$298269 |
25735 |
0.02% |
股份
|
| MYDA Advisors LLC |
$289750 |
25000 |
0.02% |
股份
|
| Arax Advisory Partners |
$282461 |
24371 |
0.02% |
股份
|
| COMMONWEALTH EQUITY SERVICES, LLC |
$281390 |
24279 |
0.02% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$277731 |
23963 |
0.02% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$272945 |
23550 |
0.02% |
股份
|
| Corient Private Wealth LP |
$269586 |
23260 |
0.02% |
股份
|
| HSBC HOLDINGS PLC |
$249891 |
21340 |
0.01% |
股份
|
| Lynx1 Capital Management LP |
$246230 |
21245 |
0.01% |
股份
|
| E Fund Management Co., Ltd. |
$234918 |
20269 |
0.01% |
股份
|
| NLB Skladi, upravljanje premozenja, d.o.o. |
$231800 |
20000 |
0.01% |
股份
|
| DKM Wealth Management, Inc. |
$231800 |
20000 |
0.01% |
股份
|
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. |
$228462 |
19712 |
0.01% |
股份
|
| KESTRA PRIVATE WEALTH SERVICES, LLC |
$224962 |
19410 |
0.01% |
股份
|
| VISTA CAPITAL PARTNERS, INC. |
$223884 |
19317 |
0.01% |
股份
|
| CAPTRUST FINANCIAL ADVISORS |
$222934 |
19235 |
0.01% |
股份
|
| Vanguard Personalized Indexing Management, LLC |
$212584 |
18342 |
0.01% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$210329 |
19314 |
0.01% |
股份
|
| Merit Financial Group, LLC |
$174904 |
15091 |
0.01% |
股份
|
| Orion Porfolio Solutions, LLC |
$174232 |
15033 |
0.01% |
股份
|
| Cresset Asset Management, LLC |
$168055 |
14500 |
0.01% |
股份
|
| Hudson Bay Capital Management LP |
$162724 |
14040 |
0.01% |
股份
|
| HB Wealth Management, LLC |
$156187 |
13476 |
0.01% |
股份
|
| Legal & General Group Plc |
$155619 |
13427 |
0.01% |
股份
|
| XPONANCE LLC |
$153394 |
13235 |
0.01% |
股份
|
| Focus Partners Wealth |
$148074 |
12776 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$145524 |
12556 |
0.01% |
股份
|
| Cetera Investment Advisers |
$127386 |
10991 |
0.01% |
股份
|
| SIH Partners, LLLP |
$126621 |
10925 |
0.01% |
股份
|
| FOX RUN MANAGEMENT, L.L.C. |
$126424 |
10908 |
0.01% |
股份
|
| Persistent Asset Partners Ltd |
$122750 |
10591 |
0.01% |
股份
|
| Cerity Partners LLC |
$118740 |
10245 |
0.01% |
股份
|
| CWM, LLC |
$118449 |
39483 |
0.01% |
股份
|
| HERITAGE OAK WEALTH ADVISORS LLC |
$115900 |
10000 |
0.01% |
股份
|
| TRUIST FINANCIAL CORP |
$115900 |
10000 |
0.01% |
股份
|
| Farther Finance Advisors, LLC |
$115471 |
9963 |
0.01% |
股份
|
| Rockefeller Capital Management L.P. |
$108379 |
9351 |
0.01% |
股份
|
| Alpha Cubed Investments, LLC |
$91543 |
26230 |
0.01% |
股份
|
| Mirae Asset Global Investments Co., Ltd. |
$80817 |
6973 |
0.00% |
股份
|
| Clarius Group, LLC |
$75300 |
30000 |
0.00% |
股份
|
| Atlatl Advisers LLC |
$57950 |
5000 |
0.00% |
股份
|
| Federation des caisses Desjardins du Quebec |
$56212 |
4850 |
0.00% |
股份
|
| Tower Research Capital LLC (TRC) |
$44819 |
3867 |
0.00% |
股份
|
| GF FUND MANAGEMENT CO. LTD. |
$36903 |
3184 |
0.00% |
股份
|
| Essential Partners LLC |
$31757 |
2740 |
0.00% |
股份
|
| State of Wyoming |
$24455 |
2110 |
0.00% |
股份
|
| Rialto Wealth Management, LLC |
$23690 |
2044 |
0.00% |
股份
|
| Global Retirement Partners, LLC |
$23180 |
2000 |
0.00% |
股份
|
| Truvestments Capital LLC |
$22311 |
1925 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$22253 |
1920 |
0.00% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$22079 |
1905 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$20816 |
1796 |
0.00% |
股份
|
| GAMMA Investing LLC |
$19367 |
1671 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$17270 |
1489993 |
0.00% |
股份
|
| Steward Partners Investment Advisory, LLC |
$15032 |
1297 |
0.00% |
股份
|
| NATIONAL BANK OF CANADA /FI/ |
$11869 |
1025 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$10083 |
870 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$10037 |
866 |
0.00% |
股份
|
| Versant Capital Management, Inc |
$9855 |
915 |
0.00% |
股份
|
| CENTRAL TRUST Co |
$9272 |
800 |
0.00% |
股份
|
| PNC Financial Services Group, Inc. |
$8588 |
741 |
0.00% |
股份
|
| 1620 INVESTMENT ADVISORS, INC. |
$6954 |
600 |
0.00% |
股份
|
| CIBC Private Wealth Group LLC |
$6095 |
2005 |
0.00% |
股份
|
| Optiver Holding B.V. |
$4323 |
373 |
0.00% |
股份
|
| CoreCap Advisors, LLC |
$4091 |
353 |
0.00% |
股份
|
| NVWM, LLC |
$2898 |
250 |
0.00% |
股份
|
| True Wealth Design, LLC |
$2620 |
226 |
0.00% |
股份
|
| Fortitude Family Office, LLC |
$2411 |
208 |
0.00% |
股份
|
| Parkside Financial Bank & Trust |
$2374 |
205 |
0.00% |
股份
|
| Silver Grove Financial Group, Inc. |
$2272 |
196 |
0.00% |
股份
|
| Noble Wealth Management PBC |
$1863 |
173 |
0.00% |
股份
|
| HRT FINANCIAL LP |
$1852 |
159833 |
0.00% |
股份
|
| Parallel Advisors, LLC |
$1437 |
124 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$1357 |
117 |
0.00% |
股份
|
| SG Americas Securities, LLC |
$1161 |
100166 |
0.00% |
股份
|
| Blue Trust, Inc. |
$1159 |
100 |
0.00% |
股份
|
| ISLAY CAPITAL MANAGEMENT, LLC |
$382 |
33 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$259 |
22376 |
0.00% |
股份
|
| Janney Montgomery Scott LLC |
$203 |
17516 |
0.00% |
股份
|
| Sunbelt Securities, Inc. |
$192 |
64 |
0.00% |
股份
|
| Arkos Global Advisors |
$116 |
10000 |
0.00% |
股份
|
| Lindbrook Capital, LLC |
$95 |
38 |
0.00% |
股份
|
| TrinityBridge Ltd |
$30 |
2555 |
0.00% |
股份
|
| Pacer Advisors, Inc. |
$28 |
2401 |
0.00% |
股份
|