| BlackRock, Inc. |
$115286283 |
10509233 |
11.48% |
股份
|
| MONTANOVA CAPITAL, LLC |
$94072379 |
8575422 |
9.37% |
股份
|
| BVF INC/IL |
$92650086 |
8445769 |
9.23% |
股份
|
| STATE STREET CORP |
$58461412 |
5329208 |
5.82% |
股份
|
| VANGUARD GROUP INC |
$57224245 |
5507627 |
5.70% |
股份
|
| VANGUARD CAPITAL MANAGEMENT LLC |
$42960319 |
3916164 |
4.28% |
股份
|
| ARMISTICE CAPITAL, LLC |
$40347660 |
3678000 |
4.02% |
股份
|
| AQR CAPITAL MANAGEMENT LLC |
$34300201 |
3126727 |
3.42% |
股份
|
| GOLDMAN SACHS GROUP INC |
$24848925 |
2265171 |
2.47% |
股份
|
| GEODE CAPITAL MANAGEMENT, LLC |
$24468022 |
2229958 |
2.44% |
股份
|
| ALETHEA CAPITAL MANAGEMENT, LLC |
$23782280 |
2167938 |
2.37% |
股份
|
| Prosight Management, LP |
$22180945 |
2021964 |
2.21% |
股份
|
| Deep Track Capital, LP |
$21704858 |
1978565 |
2.16% |
股份
|
| RENAISSANCE TECHNOLOGIES LLC |
$18251502 |
1663765 |
1.82% |
股份
|
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP |
$15470717 |
1410275 |
1.54% |
股份
|
| VANGUARD PORTFOLIO MANAGEMENT LLC |
$14589453 |
1329941 |
1.45% |
股份
|
| NAN FUNG TRINITY (HK) LTD |
$12888434 |
1174880 |
1.28% |
股份
|
| Qube Research & Technologies Ltd |
$12833627 |
1169884 |
1.28% |
股份
|
| DIMENSIONAL FUND ADVISORS LP |
$12826227 |
1169189 |
1.28% |
股份
|
| BANK OF AMERICA CORP /DE/ |
$12735304 |
1160921 |
1.27% |
股份
|
| MORGAN STANLEY |
$12728606 |
1160310 |
1.27% |
股份
|
| Connor, Clark & Lunn Investment Management Ltd. |
$10927371 |
996114 |
1.09% |
股份
|
| UBS Group AG |
$10582057 |
964636 |
1.05% |
股份
|
| JACOBS LEVY EQUITY MANAGEMENT, INC |
$10410245 |
948974 |
1.04% |
股份
|
| NORTHERN TRUST CORP |
$9117826 |
831160 |
0.91% |
股份
|
| MILLENNIUM MANAGEMENT LLC |
$7803312 |
711332 |
0.78% |
股份
|
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
$7420108 |
676400 |
0.74% |
股份
|
| Jump Financial, LLC |
$7405232 |
675044 |
0.74% |
股份
|
| VANGUARD FIDUCIARY TRUST CO |
$6906273 |
629560 |
0.69% |
股份
|
| Fisher Asset Management, LLC |
$6866520 |
625936 |
0.68% |
股份
|
| ROYCE & ASSOCIATES LP |
$6691535 |
609985 |
0.67% |
股份
|
| Rhenman & Partners Asset Management AB |
$6488755 |
591500 |
0.65% |
股份
|
| JUPITER ASSET MANAGEMENT LTD |
$5593449 |
509886 |
0.56% |
股份
|
| 1492 Capital Management LLC |
$5124668 |
467153 |
0.51% |
股份
|
| SECTOR GAMMA AS |
$4750142 |
433012 |
0.47% |
股份
|
| Man Group plc |
$4749001 |
432908 |
0.47% |
股份
|
| FMR LLC |
$3985863 |
363342 |
0.40% |
股份
|
| IEQ CAPITAL, LLC |
$3818934 |
348125 |
0.38% |
股份
|
| Susquehanna Portfolio Strategies, LLC |
$3772484 |
343891 |
0.38% |
股份
|
| CITADEL ADVISORS LLC |
$3599312 |
328105 |
0.36% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$3526855 |
321500 |
0.35% |
买入期权
|
| SPHERA FUNDS MANAGEMENT LTD. |
$3236578 |
295039 |
0.32% |
股份
|
| OP Asset Management Ltd |
$3201924 |
291880 |
0.32% |
股份
|
| Ally Bridge Group (NY) LLC |
$3181300 |
290000 |
0.32% |
股份
|
| Ishara Investments LP |
$3035948 |
276750 |
0.30% |
股份
|
| PRUDENTIAL FINANCIAL INC |
$2939412 |
267950 |
0.29% |
股份
|
| Assenagon Asset Management S.A. |
$2937196 |
267748 |
0.29% |
股份
|
| GREAT LAKES ADVISORS, LLC |
$2850631 |
259857 |
0.28% |
股份
|
| Bank of New York Mellon Corp |
$2827703 |
257767 |
0.28% |
股份
|
| JPMORGAN CHASE & CO |
$2697742 |
245920 |
0.27% |
股份
|
| Creative Planning |
$2549742 |
232429 |
0.25% |
股份
|
| Quantinno Capital Management LP |
$2267817 |
206728 |
0.23% |
股份
|
| AMERIPRISE FINANCIAL INC |
$2244615 |
204614 |
0.22% |
股份
|
| Invesco Ltd. |
$2174649 |
198236 |
0.22% |
股份
|
| Trexquant Investment LP |
$2015529 |
183731 |
0.20% |
股份
|
| TWO SIGMA INVESTMENTS, LP |
$1838364 |
167581 |
0.18% |
股份
|
| Nuveen, LLC |
$1828370 |
166670 |
0.18% |
股份
|
| SEI INVESTMENTS CO |
$1778267 |
162110 |
0.18% |
股份
|
| Swedbank AB |
$1677313 |
152900 |
0.17% |
股份
|
| Mariner, LLC |
$1626381 |
148257 |
0.16% |
股份
|
| Woodline Partners LP |
$1598373 |
145704 |
0.16% |
股份
|
| Swiss National Bank |
$1597232 |
145600 |
0.16% |
股份
|
| TWO SIGMA ADVISERS, LP |
$1585514 |
152600 |
0.16% |
股份
|
| BARCLAYS PLC |
$1574941 |
143568 |
0.16% |
股份
|
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC |
$1573564 |
159724 |
0.16% |
股份
|
| Engineers Gate Manager LP |
$1467216 |
133748 |
0.15% |
股份
|
| MARTINGALE ASSET MANAGEMENT L P |
$1413946 |
128892 |
0.14% |
股份
|
| Virtus Investment Advisers, LLC |
$1409590 |
128495 |
0.14% |
股份
|
| CITIGROUP INC |
$1390470 |
126752 |
0.14% |
股份
|
| Cerity Partners LLC |
$1361183 |
124082 |
0.14% |
股份
|
| Corient Private Wealth LP |
$1346119 |
122709 |
0.13% |
股份
|
| DAFNA Capital Management LLC |
$1322631 |
120568 |
0.13% |
股份
|
| Russell Investments Group, Ltd. |
$1240524 |
113083 |
0.12% |
股份
|
| RHUMBLINE ADVISERS |
$1190674 |
108540 |
0.12% |
股份
|
| Rosalind Advisors, Inc. |
$1097000 |
100000 |
0.11% |
股份
|
| HSBC HOLDINGS PLC |
$1055235 |
94810 |
0.11% |
股份
|
| BNP PARIBAS FINANCIAL MARKETS |
$1045112 |
95270 |
0.10% |
股份
|
| AMERICAN CENTURY COMPANIES INC |
$1033352 |
94198 |
0.10% |
股份
|
| Rangeley Capital, LLC |
$1031180 |
94000 |
0.10% |
股份
|
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
$1017939 |
92793 |
0.10% |
股份
|
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
$1009364 |
124153 |
0.10% |
股份
|
| CWM, LLC |
$1005567 |
123686 |
0.10% |
股份
|
| DEUTSCHE BANK AG\ |
$998303 |
91003 |
0.10% |
股份
|
| Xcel Wealth Management, LLC |
$998084 |
90983 |
0.10% |
股份
|
| ALPS ADVISORS INC |
$988320 |
90093 |
0.10% |
股份
|
| ACT CAPITAL MANAGEMENT, LLC |
$975233 |
88900 |
0.10% |
股份
|
| Rafferty Asset Management, LLC |
$937781 |
85486 |
0.09% |
股份
|
| MERCER GLOBAL ADVISORS INC /ADV |
$873082 |
79588 |
0.09% |
股份
|
| WELLS FARGO & COMPANY/MN |
$865687 |
78914 |
0.09% |
股份
|
| JANE STREET GROUP, LLC |
$815981 |
74383 |
0.08% |
股份
|
| VANGUARD ASSET MANAGEMENT, Ltd |
$815312 |
74322 |
0.08% |
股份
|
| Jain Global LLC |
$798945 |
72830 |
0.08% |
股份
|
| SECTORAL ASSET MANAGEMENT INC |
$784136 |
71480 |
0.08% |
股份
|
| CITADEL ADVISORS LLC |
$759124 |
69200 |
0.08% |
买入期权
|
| Aaron Wealth Advisors LLC |
$739981 |
67455 |
0.07% |
股份
|
| Nebula Research & Development LLC |
$703271 |
121884 |
0.07% |
股份
|
| ALLIANCEBERNSTEIN L.P. |
$689424 |
84800 |
0.07% |
股份
|
| Legal & General Group Plc |
$674040 |
61444 |
0.07% |
股份
|
| Zurcher Kantonalbank (Zurich Cantonalbank) |
$626859 |
57143 |
0.06% |
股份
|
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
$621341 |
56640 |
0.06% |
股份
|
| Pale Fire Capital SE |
$620902 |
56600 |
0.06% |
股份
|
| Quadrature Capital Ltd |
$611183 |
55714 |
0.06% |
股份
|
| Cubist Systematic Strategies, LLC |
$611004 |
69040 |
0.06% |
股份
|
| Knott David M Jr |
$578854 |
52767 |
0.06% |
股份
|
| MetLife Investment Management, LLC |
$546986 |
49862 |
0.05% |
股份
|
| FOX RUN MANAGEMENT, L.L.C. |
$543158 |
49513 |
0.05% |
股份
|
| STATE OF WISCONSIN INVESTMENT BOARD |
$540536 |
49274 |
0.05% |
股份
|
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. |
$540195 |
49243 |
0.05% |
股份
|
| Lion Point Capital, LP |
$504620 |
46000 |
0.05% |
股份
|
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM |
$500682 |
45641 |
0.05% |
股份
|
| CITADEL ADVISORS LLC |
$485971 |
44300 |
0.05% |
卖出期权
|
| TUDOR INVESTMENT CORP ET AL |
$477414 |
43520 |
0.05% |
股份
|
| PROFUND ADVISORS LLC |
$475506 |
43346 |
0.05% |
股份
|
| ADAR1 Capital Management, LLC |
$438800 |
40000 |
0.04% |
股份
|
| AlphaQuest LLC |
$438302 |
42185 |
0.04% |
股份
|
| JANE STREET GROUP, LLC |
$410278 |
37400 |
0.04% |
买入期权
|
| CAPTRUST FINANCIAL ADVISORS |
$402603 |
36700 |
0.04% |
股份
|
| Advantage Alpha Capital Partners LP |
$380178 |
42958 |
0.04% |
股份
|
| Quarry LP |
$373573 |
34054 |
0.04% |
股份
|
| Vanguard Global Advisers, LLC |
$366179 |
33380 |
0.04% |
股份
|
| Arax Advisory Partners |
$349668 |
31875 |
0.03% |
股份
|
| Focus Partners Wealth |
$311756 |
28418 |
0.03% |
股份
|
| LPL Financial LLC |
$304856 |
27790 |
0.03% |
股份
|
| Brevan Howard Capital Management LP |
$298757 |
27234 |
0.03% |
股份
|
| nVerses Capital, LLC |
$285472 |
26023 |
0.03% |
股份
|
| Police & Firemen's Retirement System of New Jersey |
$285275 |
26005 |
0.03% |
股份
|
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ |
$283410 |
25835 |
0.03% |
股份
|
| Vanguard Investments Australia, Ltd. |
$279450 |
25474 |
0.03% |
股份
|
| Pallas Capital Advisors LLC |
$274897 |
25059 |
0.03% |
股份
|
| Allspring Global Investments Holdings, LLC |
$260736 |
24187 |
0.03% |
股份
|
| State of New Jersey Common Pension Fund D |
$258486 |
23563 |
0.03% |
股份
|
| Merit Financial Group, LLC |
$255349 |
23277 |
0.03% |
股份
|
| NorthCrest Asset Manangement, LLC |
$255275 |
21132 |
0.03% |
股份
|
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
$253593 |
23117 |
0.03% |
股份
|
| BRIGHTON JONES LLC |
$251729 |
22947 |
0.03% |
股份
|
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC |
$243260 |
22175 |
0.02% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$241340 |
22000 |
0.02% |
卖出期权
|
| Corton Capital Inc. |
$237375 |
26822 |
0.02% |
股份
|
| NEW YORK STATE COMMON RETIREMENT FUND |
$236897 |
21595 |
0.02% |
股份
|
| FRANKLIN RESOURCES INC |
$234221 |
21351 |
0.02% |
股份
|
| ARIZONA STATE RETIREMENT SYSTEM |
$220585 |
20108 |
0.02% |
股份
|
| ROYAL BANK OF CANADA |
$219000 |
20116 |
0.02% |
股份
|
| INTECH INVESTMENT MANAGEMENT LLC |
$217864 |
19860 |
0.02% |
股份
|
| JANUS HENDERSON GROUP PLC |
$202491 |
24922 |
0.02% |
股份
|
| Flower City Capital |
$197460 |
18000 |
0.02% |
股份
|
| VOYA INVESTMENT MANAGEMENT LLC |
$181839 |
16576 |
0.02% |
股份
|
| KLP KAPITALFORVALTNING AS |
$171132 |
15600 |
0.02% |
股份
|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP |
$170869 |
15576 |
0.02% |
股份
|
| JANE STREET GROUP, LLC |
$163453 |
14900 |
0.02% |
卖出期权
|
| Integrated Wealth Concepts LLC |
$158626 |
14460 |
0.02% |
股份
|
| China Universal Asset Management Co., Ltd. |
$154984 |
14128 |
0.02% |
股份
|
| ProShare Advisors LLC |
$154260 |
14062 |
0.02% |
股份
|
| MAI Capital Management |
$145046 |
13222 |
0.01% |
股份
|
| Focus Partners Advisor Solutions, LLC |
$144508 |
13173 |
0.01% |
股份
|
| WINTON GROUP Ltd |
$142610 |
13000 |
0.01% |
股份
|
| Atria Investments, Inc |
$137048 |
12493 |
0.01% |
股份
|
| Pinnacle Wealth Planning Services, Inc. |
$134053 |
12220 |
0.01% |
股份
|
| E Fund Management Co., Ltd. |
$132232 |
12054 |
0.01% |
股份
|
| TORONTO DOMINION BANK |
$129446 |
11800 |
0.01% |
买入期权
|
| Pictet Asset Management Holding SA |
$128963 |
11756 |
0.01% |
股份
|
| STRS OHIO |
$119573 |
10900 |
0.01% |
股份
|
| Krilogy Financial LLC |
$115284 |
10509 |
0.01% |
股份
|
| Allworth Financial LP |
$113277 |
10326 |
0.01% |
股份
|
| Squarepoint Ops LLC |
$111576 |
10171 |
0.01% |
股份
|
| FEDERATED HERMES, INC. |
$96646 |
8810 |
0.01% |
股份
|
| Kemnay Advisory Services Inc. |
$93870 |
8557 |
0.01% |
股份
|
| Ameritas Investment Partners, Inc. |
$80125 |
7304 |
0.01% |
股份
|
| PNC Financial Services Group, Inc. |
$57801 |
5269 |
0.01% |
股份
|
| Mirae Asset Global Investments Co., Ltd. |
$43551 |
3970 |
0.00% |
股份
|
| EverSource Wealth Advisors, LLC |
$42915 |
3912 |
0.00% |
股份
|
| Tower Research Capital LLC (TRC) |
$37122 |
3384 |
0.00% |
股份
|
| Essential Partners LLC |
$34654 |
3159 |
0.00% |
股份
|
| Clearstead Advisors, LLC |
$31452 |
2867 |
0.00% |
股份
|
| BROWN BROTHERS HARRIMAN & CO |
$31308 |
2854 |
0.00% |
股份
|
| NISA INVESTMENT ADVISORS, LLC |
$31275 |
2851 |
0.00% |
股份
|
| IFP Advisors, Inc |
$27886 |
2542 |
0.00% |
股份
|
| COMERICA BANK |
$22541 |
2169 |
0.00% |
股份
|
| SIGNATUREFD, LLC |
$22258 |
2029 |
0.00% |
股份
|
| GF FUND MANAGEMENT CO. LTD. |
$20218 |
1843 |
0.00% |
股份
|
| FIFTH THIRD BANCORP |
$15528 |
1415 |
0.00% |
股份
|
| GAMMA Investing LLC |
$14557 |
1327 |
0.00% |
股份
|
| True Wealth Design, LLC |
$13625 |
1242 |
0.00% |
股份
|
| Versant Capital Management, Inc |
$13623 |
1272 |
0.00% |
股份
|
| Federation des caisses Desjardins du Quebec |
$13164 |
1200 |
0.00% |
股份
|
| Farther Finance Advisors, LLC |
$12264 |
1118 |
0.00% |
股份
|
| OSAIC HOLDINGS, INC. |
$12231 |
1115 |
0.00% |
股份
|
| Global Retirement Partners, LLC |
$11782 |
1074 |
0.00% |
股份
|
| Caitong International Asset Management Co., Ltd |
$10432 |
951 |
0.00% |
股份
|
| ROTHSCHILD INVESTMENT LLC |
$10081 |
919 |
0.00% |
股份
|
| CROWLEY WEALTH MANAGEMENT, INC. |
$7965 |
900 |
0.00% |
股份
|
| Rockefeller Capital Management L.P. |
$7887 |
719 |
0.00% |
股份
|
| LRI Investments, LLC |
$6373 |
581 |
0.00% |
股份
|
| Cedar Mountain Advisors, LLC |
$5946 |
542 |
0.00% |
股份
|
| US BANCORP \DE\ |
$5682 |
518 |
0.00% |
股份
|
| SJS Investment Consulting Inc. |
$4981 |
454 |
0.00% |
股份
|
| MassMutual Private Wealth & Trust, FSB |
$4783 |
436 |
0.00% |
股份
|
| Lindbrook Capital, LLC |
$4594 |
696 |
0.00% |
股份
|
| LOS ANGELES CAPITAL MANAGEMENT LLC |
$4421 |
403 |
0.00% |
股份
|
| Smartleaf Asset Management LLC |
$3785 |
345 |
0.00% |
股份
|
| SBI Securities Co., Ltd. |
$3576 |
326 |
0.00% |
股份
|
| Parallel Advisors, LLC |
$3390 |
309 |
0.00% |
股份
|
| Sterling Capital Management LLC |
$3280 |
299 |
0.00% |
股份
|
| TD Waterhouse Canada Inc. |
$3231 |
300 |
0.00% |
股份
|
| Steward Partners Investment Advisory, LLC |
$2413 |
220 |
0.00% |
股份
|
| NewEdge Advisors, LLC |
$2370 |
216 |
0.00% |
股份
|
| HRT FINANCIAL LP |
$2355 |
214747 |
0.00% |
股份
|
| Wealth Enhancement Trust Services, Inc. |
$2315 |
211 |
0.00% |
股份
|
| Janney Montgomery Scott LLC |
$1748 |
159310 |
0.00% |
股份
|
| Fortitude Family Office, LLC |
$1349 |
123 |
0.00% |
股份
|
| NATIONAL BANK OF CANADA /FI/ |
$1304 |
119 |
0.00% |
股份
|
| JONES FINANCIAL COMPANIES LLLP |
$1112 |
102 |
0.00% |
股份
|
| WPG Advisers, LLC |
$911 |
83 |
0.00% |
股份
|
| Parkside Financial Bank & Trust |
$768 |
70 |
0.00% |
股份
|
| PRICE T ROWE ASSOCIATES INC /MD/ |
$768 |
69962 |
0.00% |
股份
|
| Cornerstone Financial Management LLC |
$735 |
67 |
0.00% |
股份
|
| DekaBank Deutsche Girozentrale |
$732 |
95000 |
0.00% |
股份
|
| Rossby Financial, LCC |
$724 |
66 |
0.00% |
股份
|
| SG Americas Securities, LLC |
$695 |
63396 |
0.00% |
股份
|
| HARBOR CAPITAL ADVISORS, INC. |
$634 |
57776 |
0.00% |
股份
|
| Sunbelt Securities, Inc. |
$610 |
75 |
0.00% |
股份
|
| Triumph Capital Management |
$428 |
39 |
0.00% |
股份
|
| ACADIAN ASSET MANAGEMENT LLC |
$397 |
36262 |
0.00% |
股份
|
| Larson Financial Group LLC |
$395 |
36 |
0.00% |
股份
|
| HUNTINGTON NATIONAL BANK |
$263 |
24 |
0.00% |
股份
|
| GSA CAPITAL PARTNERS LLP |
$258 |
23537 |
0.00% |
股份
|
| JPL Wealth Management, LLC |
$198 |
18 |
0.00% |
股份
|
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO |
$105 |
9545 |
0.00% |
股份
|
| CANADA LIFE ASSURANCE Co |
$69 |
6268 |
0.00% |
股份
|
| Hughes Financial Services, LLC |
$22 |
2 |
0.00% |
股份
|
| Pacer Advisors, Inc. |
$16 |
1428 |
0.00% |
股份
|
| CoreCap Advisors, LLC |
$11 |
1 |
0.00% |
股份
|
| Covestor Ltd |
$0 |
43 |
0.00% |
股份
|
| Capital Advisors, Ltd. LLC |
$0 |
13 |
0.00% |
股份
|