PRLD Prelude Therapeutics Incorporated - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$4.33
Price · May 20, 2026
Fundamentals as of May 12, 2026
52W Range
$1–$6
75% of range
Analyst Rating
BUY
9 analysts
Price Target
$7
+59% upside
P/E (TTM)
-2.2
ROE
-137.7%
Net Profit Margin
-819.6%

PRLD Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$4.33
Market Cap
—
P/E (TTM)
-2.2
EPS (TTM)
$-1.29
Revenue (TTM)
$12M
Div Yield
—
ROE
-137.7%
Debt/Equity
—
52W Range
$1 – $6

PRLD Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $12M
2-point trend, +73.4%
2024-12-31 → 2025-12-31
EPS $-1.29
5-point trend, +46.9%
2021-12-31 → 2025-12-31
Free Cash Flow $-56M
6-point trend, -20.5%
2020-12-31 → 2025-12-31
Margins -819.6%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
PRLD
Peer Median
P/E (TTM)
5-point trend, +56.1%
-2.2
9.4

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
PRLD
Peer Median
Operating Margin
2-point trend, +56.8%
-861.3%
—
Net Profit Margin
2-point trend, +54.9%
-819.6%
-205.9%
ROA
5-point trend, -48.7%
-62.8%
-30.4%
ROE
5-point trend, -268.2%
-137.7%
-54.4%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
PRLD
Peer Median
Current Ratio
5-point trend, -87.0%
2.0
3.8
Quick Ratio
5-point trend, -87.2%
1.9
—

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
PRLD
Peer Median
Revenue YoY
2-point trend, +73.4%
73.4%
—

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
PRLD
Peer Median
EPS (Diluted)
5-point trend, +46.9%
$-1.29
—

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
PRLD
Peer Median

PRLD Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 9 analysts
  • Strong Buy 3 33.3%
  • Buy 5 55.6%
  • Hold 1 11.1%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

4 analysts · 2026-05-14
Median target $7.00 +61.7%
Mean target $6.88 +58.8%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.03%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.13 $-0.25 0.12%
Dec. 31, 2025 $-0.20 $-0.03 -0.17%
Sept. 30, 2025 $-0.26 $-0.37 0.11%
June 30, 2025 $-0.41 $-0.45 0.04%
March 31, 2025 $-0.42 $-0.48 0.06%

Peer Comparison Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PRLD — -2.2 73.4% -819.6% -137.7% —
ELDN $114M -2.9 — — -69.4% —
RGNX $733M -3.8 104.5% -113.8% -122.5% —
NVCT $194M -5.7 — — -149.9% —
SABS — — — — — —
MGNX $102M -1.4 -0.31% -49.9% -87.0% —
ALXO $61M -0.6 — — -225.0% —
AKBA $427M -80.5 47.5% -2.3% -17.3% —
TARA $286M -4.0 — — -33.7% —
ZNTL $93M -0.7 — — -49.5% —

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 13
Annual Income Statement data for PRLD
Metric Trend 20252024
Revenue 2-point trend, +73.4% $12M $7M
R&D Expense 2-point trend, -20.1% $94M $118M
SG&A Expense 2-point trend, -22.0% $22M $29M
Operating Expenses 2-point trend, -20.5% $117M $147M
Operating Income 2-point trend, +25.2% $-105M $-140M
Other Non-op 2-point trend, -59.6% $5M $13M
Income Tax Flat — no change across 2 periods $0 $0
Net Income 2-point trend, +21.8% $-99M $-127M
EPS (Basic) 2-point trend, +23.2% $-1.29 $-1.68
EPS (Diluted) 2-point trend, +23.2% $-1.29 $-1.68
Shares (Basic) 2-point trend, +1.5% 76,956,194 75,805,840
Shares (Diluted) 2-point trend, +1.5% 76,956,194 75,805,840
EBITDA 2-point trend, +25.4% $-103M $-138M
Balance Sheet 18
Annual Balance Sheet data for PRLD
Metric Trend 20252024
Cash & Equivalents 2-point trend, +182.6% $35M $12M
Short-term Investments 2-point trend, -43.9% $68M $121M
Prepaid Expense 2-point trend, +8.6% $2M $2M
Current Assets 2-point trend, -22.2% $106M $136M
PP&E (Net) 2-point trend, -24.4% $5M $7M
PP&E (Gross) 2-point trend, +0.1% $12M $12M
Accum. Depreciation 2-point trend, +31.8% $7M $5M
Total Assets 2-point trend, -19.5% $141M $176M
Accounts Payable 2-point trend, -48.5% $4M $8M
Accrued Liabilities 2-point trend, -17.6% $13M $15M
Current Liabilities 2-point trend, +106.7% $53M $26M
Capital Leases 2-point trend, -1.8% $15M $15M
Other Non-current Liabilities 2-point trend, -8.1% $3M $3M
Total Liabilities 2-point trend, +65.0% $73M $44M
Retained Earnings 2-point trend, -17.1% $-683M $-584M
AOCI 2-point trend, -77.1% $8.0K $35.0K
Stockholders' Equity 2-point trend, -47.8% $69M $131M
Liabilities + Equity 2-point trend, -19.5% $141M $176M
Cash Flow 11
Annual Cash Flow data for PRLD
Metric Trend 20252024
D&A 2-point trend, -3.4% $2M $2M
Stock-based Comp 2-point trend, -44.2% $12M $21M
Restructuring $1M ·
Other Non-cash 2-point trend, +2431.8% $30M $1M
Operating Cash Flow 2-point trend, +45.3% $-56M $-103M
CapEx 2-point trend, -91.2% $67.0K $764.0K
Investing Cash Flow 2-point trend, -40.7% $53M $90M
Financing Cash Flow 2-point trend, +20780.0% $25M $-120.0K
Net Change in Cash 2-point trend, +271.4% $22M $-13M
Taxes Paid Flat — no change across 2 periods $0 $0
Free Cash Flow 2-point trend, +45.6% $-56M $-104M
Profitability 5
Annual Profitability data for PRLD
Metric Trend 20252024
Operating Margin 2-point trend, +56.8% -861.3% -1995.9%
Net Margin 2-point trend, +54.9% -819.6% -1816.8%
EBITDA Margin 2-point trend, +57.0% -847.2% -1970.6%
ROA 2-point trend, -11.9% -62.8% -56.1%
ROE 2-point trend, -55.9% -137.7% -88.3%
Liquidity & Solvency 2
Annual Liquidity & Solvency data for PRLD
Metric Trend 20252024
Current Ratio 2-point trend, -62.4% 2.0 5.3
Quick Ratio 2-point trend, -62.6% 1.9 5.2
Efficiency 1
Annual Efficiency data for PRLD
Metric Trend 20252024
Asset Turnover 2-point trend, +147.9% 0.1 0.0
Per Share 3
Annual Per Share data for PRLD
Metric Trend 20252024
Revenue / Share 2-point trend, +71.0% $0.16 $0.09
Cash Flow / Share 2-point trend, +46.1% $-0.73 $-1.36
EPS (TTM) 2-point trend, +23.2% $-1.29 $-1.68
Growth Rates 1
Annual Growth Rates data for PRLD
Metric Trend 20252024
Revenue YoY 73.4% ·
Valuation (TTM) 4
Annual Valuation (TTM) data for PRLD
Metric Trend 20252024
Revenue TTM 2-point trend, +73.4% $12M $7M
Net Income TTM 2-point trend, +21.8% $-99M $-127M
P/E 2-point trend, -196.2% -2.2 -0.8
Earnings Yield 2-point trend, +66.2% -44.5% -131.8%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $12M$7M———
Operating Margin % -861.3%-1995.9%———
Net Income $-99M$-127M$-122M$-115M$-112M
Diluted EPS $-1.29$-1.68$-2.02$-2.44$-2.43
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 2.05.310.89.415.4
Quick Ratio 1.95.210.79.315.2
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-56M$-104M$-111M$-87M$-86M

Latest News Recent headlines mentioning this company

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