OBIO — Institutional owners (13F)
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| RTW INVESTMENTS, LP | $41,234,412 | 9,556,063 | 33.19% | Shares |
| PERCEPTIVE ADVISORS LLC | $21,738,564 | 5,037,906 | 17.50% | Shares |
| BlackRock, Inc. | $10,832,320 | 2,510,387 | 8.72% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $8,728,883 | 2,022,916 | 7.03% | Shares |
| VANGUARD GROUP INC | $6,658,907 | 1,604,556 | 5.36% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $4,350,317 | 1,007,908 | 3.50% | Shares |
| Alyeska Investment Group, L.P. | $4,315,000 | 1,000,000 | 3.47% | Shares |
| Propel Bio Management, LLC | $3,869,265 | 896,701 | 3.11% | Shares |
| STATE STREET CORP | $2,226,756 | 516,050 | 1.79% | Shares |
| RICE HALL JAMES & ASSOCIATES, LLC | $1,829,560 | 424,000 | 1.47% | Shares |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1,508,282 | 349,544 | 1.21% | Shares |
| NORTHERN TRUST CORP | $1,482,807 | 343,640 | 1.19% | Shares |
| UBS Group AG | $1,405,711 | 325,773 | 1.13% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $1,261,072 | 292,253 | 1.01% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1,186,508 | 274,973 | 0.95% | Shares |
| Knott David M Jr | $1,094,504 | 253,651 | 0.88% | Shares |
| Flat Footed LLC | $1,084,670 | 251,372 | 0.87% | Shares |
| Simplify Asset Management Inc. | $946,655 | 219,387 | 0.76% | Shares |
| GOLDMAN SACHS GROUP INC | $775,000 | 179,606 | 0.62% | Shares |
| DAFNA Capital Management LLC | $547,319 | 126,841 | 0.44% | Shares |
| AMH Equity Ltd | $411,680 | 166,000 | 0.33% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $388,350 | 90,000 | 0.31% | Shares |
| IFP Advisors, Inc | $386,659 | 89,608 | 0.31% | Shares |
| Daytona Street Capital LLC | $379,336 | 96,398 | 0.31% | Shares |
| Bank of New York Mellon Corp | $371,534 | 86,103 | 0.30% | Shares |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $347,789 | 80,600 | 0.28% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $283,944 | 65,804 | 0.23% | Shares |
| CITADEL ADVISORS LLC | $242,464 | 56,191 | 0.20% | Shares |
| Nuveen, LLC | $224,889 | 52,118 | 0.18% | Shares |
| Holos Integrated Wealth LLC | $204,316 | 51,595 | 0.16% | Shares |
| Cubist Systematic Strategies, LLC | $193,172 | 77,892 | 0.16% | Shares |
| NewEdge Advisors, LLC | $190,218 | 44,083 | 0.15% | Shares |
| Y-Intercept (Hong Kong) Ltd | $187,642 | 43,486 | 0.15% | Shares |
| DEUTSCHE BANK AG\ | $171,383 | 39,672 | 0.14% | Shares |
| XTX Topco Ltd | $167,482 | 38,814 | 0.13% | Shares |
| WELLS FARGO & COMPANY/MN | $156,876 | 36,356 | 0.13% | Shares |
| HighTower Advisors, LLC | $152,643 | 35,375 | 0.12% | Shares |
| LASRY MARC | $150,955 | 60,869 | 0.12% | Shares |
| Affinity Asset Advisors, LLC | $144,121 | 33,400 | 0.12% | Shares |
| RHUMBLINE ADVISERS | $137,813 | 31,940 | 0.11% | Shares |
| MORGAN STANLEY | $125,826 | 29,160 | 0.10% | Shares |
| ALGERT GLOBAL LLC | $122,917 | 28,486 | 0.10% | Shares |
| Meramec Financial Planners, LLC | $114,600 | 30,000 | 0.09% | Shares |
| TWO SIGMA ADVISERS, LP | $112,465 | 27,100 | 0.09% | Shares |
| AXQ CAPITAL, LP | $109,808 | 25,448 | 0.09% | Shares |
| Invesco Ltd. | $106,533 | 24,689 | 0.09% | Shares |
| MetLife Investment Management, LLC | $103,534 | 23,994 | 0.08% | Shares |
| BANK OF AMERICA CORP /DE/ | $102,792 | 23,822 | 0.08% | Shares |
| JPMORGAN CHASE & CO | $99,181 | 20,880 | 0.08% | Shares |
| TWO SIGMA INVESTMENTS, LP | $97,359 | 22,563 | 0.08% | Shares |
| CANADA PENSION PLAN INVESTMENT BOARD | $91,047 | 21,100 | 0.07% | Shares |
| NEW YORK STATE COMMON RETIREMENT FUND | $88,026 | 20,400 | 0.07% | Shares |
| CITIGROUP INC | $87,012 | 20,165 | 0.07% | Shares |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $79,189 | 18,352 | 0.06% | Shares |
| CITADEL ADVISORS LLC | $75,944 | 17,600 | 0.06% | Put option |
| JANE STREET GROUP, LLC | $66,278 | 15,360 | 0.05% | Shares |
| Vanguard Global Advisers, LLC | $60,186 | 13,948 | 0.05% | Shares |
| BARCLAYS PLC | $58,331 | 13,518 | 0.05% | Shares |
| ABLE Financial Group, LLC | $57,830 | 13,402 | 0.05% | Shares |
| Sargent Investment Group, LLC | $56,613 | 13,120 | 0.05% | Shares |
| Frec Markets, Inc. | $56,302 | 13,048 | 0.05% | Shares |
| CITADEL ADVISORS LLC | $52,212 | 12,100 | 0.04% | Call option |
| Police & Firemen's Retirement System of New Jersey | $50,723 | 11,755 | 0.04% | Shares |
| JANE STREET GROUP, LLC | $49,191 | 11,400 | 0.04% | Put option |
| Garden State Investment Advisory Services LLC | $45,575 | 10,562 | 0.04% | Shares |
| China Universal Asset Management Co., Ltd. | $41,122 | 9,530 | 0.03% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $35,443 | 8,214 | 0.03% | Shares |
| Point72 Asia (Singapore) Pte. Ltd. | $23,178 | 9,346 | 0.02% | Shares |
| Legal & General Group Plc | $16,932 | 3,924 | 0.01% | Shares |
| Ameritas Investment Partners, Inc. | $15,607 | 3,617 | 0.01% | Shares |
| Tower Research Capital LLC (TRC) | $15,538 | 3,601 | 0.01% | Shares |
| Russell Investments Group, Ltd. | $13,751 | 3,187 | 0.01% | Shares |
| Mirae Asset Global Investments Co., Ltd. | $11,556 | 2,678 | 0.01% | Shares |
| SIMPLEX TRADING, LLC | $11,063 | 2,564 | 0.01% | Shares |
| ROYAL BANK OF CANADA | $8,000 | 1,864 | 0.01% | Shares |
| AdvisorNet Financial, Inc | $7,318 | 1,696 | 0.01% | Shares |
| GF FUND MANAGEMENT CO. LTD. | $5,062 | 1,173 | 0.00% | Shares |
| JONES FINANCIAL COMPANIES LLLP | $3,765 | 888 | 0.00% | Shares |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2,369 | 549 | 0.00% | Shares |
| FMR LLC | $1,142 | 265 | 0.00% | Shares |
| Point72 (DIFC) Ltd | $675 | 272 | 0.00% | Shares |
| Sterling Capital Management LLC | $604 | 140 | 0.00% | Shares |
| Optiver Holding B.V. | $173 | 40 | 0.00% | Shares |
| PRICE T ROWE ASSOCIATES INC /MD/ | $142 | 32,689 | 0.00% | Shares |
| Caitong International Asset Management Co., Ltd | $65 | 15 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $26 | 6 | 0.00% | Shares |