VKTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $29.94
Market Cap (MRQ) $3.49B
P/E (TTM) -6.4
EPS (TTM) $-4.67
Revenue (TTM) $0
ROE (TTM) -88.9%
52W Range $27–$43

VKTX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$0
2016-12-31 → 2025-12-31
EPS$-3.19
2021-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend VKTX 5Y avg Peer Median Verdict
P/E (TTM) -6.45Y avg ≈-17.6 ≈-17.6 · ·
P/B (MRQ) 8.65Y avg ≈4.7 ≈4.7 4.0 Overvalued
Price / Cash Flow -12.35Y avg ≈-22.8 ≈-22.8 · ·
Price / Tangible Book 5.45Y avg ≈4.7 ≈4.7 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise -23.1%
Next Report Oct 20, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Jul 21, 2026 $-1.10 $-1.27 13.5%
March 31, 2026 $-1.37 $-1.03 -32.5%
Dec. 31, 2025 $-1.38 $-0.91 -51.3%
Sept. 30, 2025 $-0.81 $-0.69 -17.2%
June 30, 2025 $-0.58 $-0.46 -27.4%
March 31, 2025 $-0.41 $-0.33 -23.9%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $0$0$0$0$0$0$0$0$0$0$0$0
R&D Expense $345M$102M$64M$54M$45M$32M$24M$19M$14M$9M$7M$22M
SG&A Expense $48M$49M$37M$16M$11M$11M$9M$7M$5M$5M$5M$1M
Operating Expenses $393M$151M$101M$70M$56M$43M$33M$26M$19M$14M$12M$23M
Operating Income $-393M$-151M$-101M$-70M$-56M$-43M$-33M$-26M$-19M$-14M$-12M$-23M
Other Non-op $34M$41M$15M$1M$692.0K$3M$7M$4M$-2M$-884.5K$-11M$2M
Pretax Income $-360M$-110M$-86M·········
Income Tax $1.0K$1.0K$1.0K$1.0K$2.0K$0$0$0$0$0··
Net Income $-360M$-110M$-86M$-69M$-55M$-39M$-26M$-22M$-21M$-15M$-23M$-22M
EPS (Basic) $-3.19$-1.01$-0.91$-0.90$-0.71·······
EPS (Diluted) $-3.19$-1.01$-0.91$-0.90$-0.71·······
Shares (Basic) 112,667,000109,037,00094,347,00076,834,00077,198,000·······
Shares (Diluted) 112,667,000109,037,00094,347,00076,834,00077,198,000·······
EBITDA $-393M$-151M$-101M$-70M$-56M$-43M$-33M$-26M$-19M$-14M$-12M·
Balance Sheet 16
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $166M$27M$56M$37M$26M$29M$8M$25M$9M$3M$768.5K$755.9K
Short-term Investments ·····$219M$267M$277M$12M$10M$13M·
Prepaid Expense $2M$1M$3M$3M$619.0K$442.0K$405.0K$278.0K$389.0K$282.7K$1M$17.8K
Current Assets $716M$907M$367M$167M$211M$256M$284M$302M$22M$14M$15M$773.7K
Other Non-current Assets ···········$775
Total Assets $716M$908M$368M$169M$211M$257M$284M$302M$22M$15M$15M$3M
Accounts Payable $53M$10M$8M$9M$1M$4M$2M$959.0K$2M$1M$592.4K$2M
Current Liabilities $77M$27M$19M$22M$9M$12M$7M$5M$9M$6M$2M$23M
Capital Leases $0$630.0K$936.0K$1M·$29.0K$360.0K·····
Total Liabilities $77M$28M$20M$23M$9M$12M$7M$5M$9M$6M$7M$25M
Common Stock $1.0K$1.0K$1.0K$1.0K$1.0K$1.0K$1.0K$1.0K$358$208$97$60
Retained Earnings $-848M$-488M$-378M$-292M$-223M$-168M$-129M$-103M$-81M$-60M$-46M$-22M
Treasury Stock $0$0$7M$7M········
Stockholders' Equity $639M$880M$348M$145M$202M$244M$277M$298M$13M$8M$9M$-22M
Liabilities + Equity $716M$908M$368M$169M$211M$257M$284M$302M$22M$15M$15M$3M
Shares Outstanding 114,793,067111,573,519100,113,77078,257,25878,248,40173,215,94072,413,60271,742,04335,817,10420,823,8739,683,7416,000,000
Cash Flow 8
Metric Trend 202520242023202220212020201920182017201620152014
Stock-based Comp $41M$30M$17M$9M$6M$6M$4M$3M$1M$2M$3M$6.3K
Operating Cash Flow $-279M$-88M$-73M$-48M$-48M$-22M$-25M$-19M$-15M$-11M$-9M$-2M
Investing Cash Flow $341M$-553M$-179M$55M$38M$42M$7M$-266M$-2M···
Stock Issued ·······$297M$22M$12M$25M·
Stock Repurchased ···$7M·····$229$38$2
Net Stock Activity ···$-7M···$297M$22M$12M$25M·
Financing Cash Flow $76M$612M$271M$4M$7M$950.0K$887.0K$300M$22M···
Net Change in Cash ···$11M$-3M$21M$-16M$16M$6M$2M$12.7K$576.2K
Profitability 3
Metric Trend 202520242023202220212020201920182017201620152014
ROA -44.3%-17.2%-32.0%-36.3%-23.5%-14.6%-8.8%-13.6%-112.3%-98.3%-253.3%·
ROE -47.3%-17.9%-34.8%-39.7%-24.6%-15.2%-9.0%-14.2%-191.3%-175.7%349.2%·
ROIC -61.6%···········
Liquidity & Solvency 2
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 9.333.119.27.624.021.141.866.42.52.27.7·
Quick Ratio 2.21.02.91.73.020.540.766.32.42.07.1·
Efficiency 1
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.00.00.00.00.00.00.00.00.00.00.0·
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $5.57$7.89$3.48$1.86$2.58$3.34$3.83$4.15$0.38$0.39$0.90·
Revenue / Share $0.00$0.00$0.00$0.00········
Cash Flow / Share $-2.47$-0.81$-0.78$-0.63········
Cash / Share $1.44$0.24$0.55$0.47$0.34$0.40$0.12$0.35$0.25$0.15$0.08·
EPS (TTM) $-3.19$-1.01$-0.91$-0.90$-0.71·······
Valuation (TTM) 8
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $0$0$0$0$0$0$0$0$0$0$0·
Net Income TTM $-360M$-110M$-86M$-69M$-55M$-39M$-26M$-22M$-21M$-15M$-23M·
Market Cap $4.04B$4.49B$1.86B$736M$360M$412M$581M$549M$145M$25M$33M·
P/E -11.0-39.8-20.5-10.4-6.5·······
P/B 6.35.15.35.11.81.72.11.810.83.13.8·
P / Tangible Book 6.35.15.35.11.81.7······
P / Cash Flow -14.5-51.1-25.4-15.2-7.6-18.9-23.5-29.3-9.9-2.2-3.8·
Earnings Yield -9.1%-2.5%-4.9%-9.6%-15.4%·······

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $0 $0 $0 $0 $0
Net Income $-360M $-110M $-86M $-69M $-55M
Diluted EPS $-3.19 $-1.01 $-0.91 $-0.90 $-0.71

Institutional owners (13F) 499 filers · $3.8B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 499
Value held $3.8B
New positions 84
Exited positions 44
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
84 (+8 vs prior Q) 44 (-25 vs prior Q) 153 (-5 vs prior Q) 133 (+4 vs prior Q) +5.8M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
VANGUARD GROUP INC $351,254,252 9,984,487 9.30% Shares
FMR LLC $247,157,830 6,335,756 6.54% Shares
BlackRock, Inc. $241,458,213 6,189,649 6.39% Shares
STATE STREET CORP $218,705,430 5,606,394 5.79% Shares
VANGUARD CAPITAL MANAGEMENT LLC $197,143,394 5,053,663 5.22% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $174,931,100 4,484,263 4.63% Shares
TWO SIGMA INVESTMENTS, LP $153,598,520 3,937,414 4.07% Shares
MORGAN STANLEY $135,990,439 3,486,040 3.60% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $113,382,565 2,906,500 3.00% Call option
AMERIPRISE FINANCIAL INC $84,108,797 2,156,083 2.23% Shares
GEODE CAPITAL MANAGEMENT, LLC $81,865,360 2,097,981 2.17% Shares
TWO SIGMA ADVISERS, LP $74,906,241 2,129,228 1.98% Shares
AMERICAN CENTURY COMPANIES INC $70,844,186 1,816,050 1.88% Shares
D. E. Shaw & Co., Inc. $62,649,826 1,605,994 1.66% Shares
DIADEMA PARTNERS LP $47,623,408 1,220,800 1.26% Call option
SUSQUEHANNA INTERNATIONAL GROUP, LLP $46,039,602 1,180,200 1.22% Put option
CITADEL ADVISORS LLC $43,773,121 1,122,100 1.16% Call option
BNP PARIBAS FINANCIAL MARKETS $38,296,117 981,700 1.01% Shares
CITADEL ADVISORS LLC $37,118,600 951,515 0.98% Shares
GOLDMAN SACHS GROUP INC $36,780,227 942,841 0.97% Shares
UBS Group AG $36,515,505 936,055 0.97% Shares
JPMORGAN CHASE & CO $36,387,793 915,185 0.96% Shares
JANE STREET GROUP, LLC $35,091,757 899,558 0.93% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $31,846,477 816,367 0.84% Shares
RAYMOND JAMES FINANCIAL INC $30,999,667 794,660 0.82% Shares
VANGUARD FIDUCIARY TRUST CO $28,557,153 732,047 0.76% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $28,504,217 730,690 0.75% Shares
Pictet Asset Management Holding SA $26,640,280 682,909 0.71% Shares
Vestal Point Capital, LP $26,526,800 680,000 0.70% Shares
NORTHERN TRUST CORP $24,448,309 626,719 0.65% Shares
CITADEL ADVISORS LLC $23,530,832 603,200 0.62% Put option
Eversept Partners, LP $23,519,987 602,922 0.62% Shares
BlackBarn Capital Partners LP $23,406,000 600,000 0.62% Shares
Jump Financial, LLC $22,621,196 579,882 0.60% Shares
ADAR1 Capital Management, LLC $22,393,222 574,038 0.59% Shares
DIMENSIONAL FUND ADVISORS LP $21,067,468 540,053 0.56% Shares
JANE STREET GROUP, LLC $20,870,350 535,000 0.55% Call option
Connor, Clark & Lunn Investment Management Ltd. $20,698,979 530,607 0.55% Shares
Caption Management, LLC $20,511,458 525,800 0.54% Call option
TANG CAPITAL MANAGEMENT LLC $19,505,000 500,000 0.52% Shares
MILLENNIUM MANAGEMENT LLC $19,433,690 498,172 0.51% Shares
PRINCIPAL FINANCIAL GROUP INC $19,290,796 494,509 0.51% Shares
Point72 Asset Management, L.P. $18,463,745 473,308 0.49% Shares
Clearbridge Investments, LLC $17,350,907 444,781 0.46% Shares
DIADEMA PARTNERS LP $17,234,930 441,808 0.46% Shares
BLAIR WILLIAM & CO/IL $16,258,035 416,766 0.43% Shares
Bank of New York Mellon Corp $15,909,848 407,840 0.42% Shares
ExodusPoint Capital Management, LP $15,346,650 393,000 0.41% Call option
BANK OF AMERICA CORP /DE/ $14,971,064 383,775 0.40% Shares
Walleye Trading LLC $14,964,236 383,600 0.40% Call option

Show all 499 institutional owners →

Company insiders 17 insiders · 9 officers · 8 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Brian Lian President & CEO July 29, 2026 S 2,572,441 0 6 $-14,005,897
Greg Zante Chief Financial Officer July 29, 2026 S 212,204 0 6 $-2,823,737
Marianna Mancini Chief Operating Officer July 29, 2026 S 422,760 0 6 $-2,727,473
Michael Dinerman Chief Operating Officer May 4, 2015 C 694,116 0 0 $0
Hubert C Chen Chief Medical Officer June 1, 2026 A · 0 0 $0
Neil William Aubuchon Chief Commercial Officer March 10, 2026 P 4,475 1 0 $149,912
Michael Morneau VP, Finance and Administration Jan. 19, 2021 F 116,062 0 0 $0
Hiroko Masamune Chief Development Officer Jan. 3, 2019 A 141,063 0 0 $0
Rochelle Hanley Chief Medical Officer May 4, 2016 F 160,836 0 0 $0
Dorothy Elizabeth Kelly-Gemmell Director Aug. 1, 2026 A 6,333 0 0 $0
Sarah Kathryn Rouan Director Jan. 2, 2026 A 4,390 0 0 $0
Lawson Macartney Director Jan. 2, 2026 A 51,115 0 0 $0
Charles A Rowland Jr Director Jan. 2, 2026 A 33,150 0 1 $-2,134,200
Matthew J Singleton Director Jan. 2, 2026 A 12,650 0 0 $0
Matthew W Foehr Director Jan. 2, 2026 A 135,186 0 1 $-561,760
Stephen W Webster Director Jan. 2, 2020 A 8,000 0 0 $0
Ligand Pharmaceuticals Incorporated 10% owner Aug. 26, 2020 S 5,819,383 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 45 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
LABU · Direxion Shares ETF Trust 0.78% 121,599 NS July 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.74% 10,811 NS July 31, 2026 N-PORT
ESSC · Strategy Shares 0.31% 3,463 NS July 31, 2026 N-PORT
PWS · Pacer Funds Trust 0.22% 1,661 NS July 31, 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0.15% 4,217 NS July 31, 2026 N-PORT
FFSM · FIDELITY COVINGTON TRUST 0.15% 69,539 NS July 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.14% 29,780 NS July 31, 2026 N-PORT
VBK · VANGUARD INDEX FUNDS 0.12% 1,464,336 SH Aug. 19, 2026 Daily
EQAL · Invesco Exchange-Traded Fund Trust … 0.09% 23,527 SH Oct. 2, 2026 Daily
VHT · VANGUARD WORLD FUND 0.06% 330,703 SH Aug. 19, 2026 Daily
IYH · iShares Trust 0.06% 66,102 SH Sept. 11, 2026 Daily
ESML · iShares Trust 0.06% 50,114 SH Sept. 11, 2026 Daily
ISCG · iShares Trust 0.05% 16,143 SH Sept. 11, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.05% 52,319 NS July 31, 2026 N-PORT
SMMD · iShares Trust 0.05% 60,016 SH Sept. 11, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.05% 1,332,828 SH Aug. 19, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.05% 2,530,231 SH Aug. 19, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.04% 37,316 SH Oct. 2, 2026 Daily
IWS · iShares Trust 0.03% 156,686 SH Sept. 11, 2026 Daily
WSML · iShares Trust 0.03% 6,550 SH Sept. 11, 2026 Daily
IWR · iShares Trust 0.03% 462,379 SH Sept. 11, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.01% 3,501,108 SH Aug. 19, 2026 Daily
VONE · VANGUARD SCOTTSDALE FUNDS 0.01% 19,254 SH Aug. 19, 2026 Daily
VONV · VANGUARD SCOTTSDALE FUNDS 0.01% 63,630 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.01% 9,458 SH Aug. 19, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 48,216 NS July 31, 2026 N-PORT
ESGV · VANGUARD WORLD FUND 0.01% 25,563 SH Aug. 19, 2026 Daily
IWD · iShares Trust 0.01% 234,063 SH Sept. 11, 2026 Daily
REVS · Columbia ETF Trust I 0.01% 922 NS July 31, 2026 N-PORT
IWP · iShares Trust 0.01% 46,707 SH Sept. 11, 2026 Daily
ITOT · iShares Trust 0.01% 158,911 SH Sept. 11, 2026 Daily
RECS · Columbia ETF Trust I 0.01% 9,430 NS July 31, 2026 N-PORT
IWB · iShares Trust 0.00% 73,105 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 28,131 SH Sept. 10, 2026 Daily
TILT · FlexShares Trust 0.00% 1,106 NS July 31, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 9,683 NS July 31, 2026 N-PORT
DCOR · Dimensional ETF Trust 0.00% 1,044 NS July 31, 2026 N-PORT
IWF · iShares Trust 0.00% 33,127 SH Sept. 11, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 1,939 NS July 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.00% 6,609 NS July 31, 2026 N-PORT
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.00% 92,569 SH Aug. 19, 2026 Daily
VONG · VANGUARD SCOTTSDALE FUNDS 0.00% 12,830 SH Aug. 19, 2026 Daily
ISCB · iShares Trust · 4,916 SH Sept. 11, 2026 Daily
ISCV · iShares Trust · 12,964 SH Sept. 11, 2026 Daily
SMLF · iShares Trust · 40,261 SH Sept. 11, 2026 Daily

VKTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 26 analysts BUY
Median target $95.00 +217.3%
9 34.6% Strong Buy
14 53.8% Buy
3 11.5% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

19 analysts · 2026-09-30

Mean target $94.82 +216.7%

← Below all targets Current price $29.94
Low$38.00 Mean$94.82 High$125.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

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FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
VKTX $4.04B -11.0 · · -47.3% ·
RLAY $1.47B -5.3 53.4% -1800.6% -44.9% ·
TNGX $1.20B -10.2 48.3% -162.8% -42.2% ·
LEGN · -26.8 · · -29.1% ·
PBLS · · · · · ·
VCYT $3.34B 51.3 16.0% 12.8% 5.2% 70.1%
IDYA $3.04B -27.0 3024.4% -52.0% -11.5% ·
CELC $4.81B -26.3 · · -244.3% ·

Latest News Recent headlines mentioning this company

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Trading Signals Recent buy/sell signals with entry price and risk/reward ratio

25

No open signal right now — no card is filled, and that's honest.

My Metrics Your personal watchlist — selected rows from Full Fundamentals

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Source: SEC 10-Q filed Jul 29, 2026