your badges 52W Range $7–$34 60% of range Analyst Rating BUY 19 analysts Price Target $45 +94% upside P/E -27.3 ROE -21.3% Net Profit Margin -229.9%

TNGX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $23.24
Market Cap (MRQ) $3.91B
P/E (TTM) -27.3
EPS (TTM) $-0.85
Revenue (TTM) $54M
ROE (TTM) -21.3%
52W Range $7–$34

TNGX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
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About Tango Therapeutics, Inc. - Common Stock Company overview from Wikipedia

05 · wikidata
sectorHealthcare industryBiotechnology employees137 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$62M
2020-12-31 → 2025-12-31
EPS$-0.87
2021-12-31 → 2025-12-31
Free Cash Flow$-140M
2021-12-31 → 2025-12-31
Net margin-229.9%
2021-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend TNGX 5Y avg Peer Median Verdict
P/E (TTM) -27.35Y avg ≈-7.9 ≈-7.9 · ·
P/S (TTM) 72.75Y avg ≈21.3 ≈21.3 246.4 Undervalued
P/B (MRQ) 3.85Y avg ≈2.9 ≈2.9 4.6 Overvalued
Price / FCF (TTM) -27.15Y avg ≈-8.1 ≈-8.1 · ·
Price / Cash Flow (TTM) -27.25Y avg ≈-8.3 ≈-8.3 · ·
Price / Tangible Book 9.15Y avg ≈2.9 ≈2.9 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 59.6%
Next Report Nov 02, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 12, 2026 $-0.37 $-0.32 -13.9%
March 31, 2026 May 13, 2026 $-0.32 $-0.32 -0.13%
Dec. 31, 2025 $-0.29 $-0.33 11.2%
Sept. 30, 2025 $0.14 $-0.05 360.2%
June 30, 2025 $-0.35 $-0.35 1.4%
March 31, 2025 $-0.36 $-0.36 -0.84%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 14
Metric Trend 202520242023202220212020
Revenue $62M$42M$37M$25M$37M$8M
R&D Expense $132M$144M$115M$106M$78M$50M
SG&A Expense $42M$44M$36M$30M$18M$10M
Operating Expenses $174M$188M$151M$136M$95M$60M
Operating Income $-111M$-146M$-114M$-111M$-58M$-52M
Other Non-op $4M$8M$6M$1M$-248.0K$120.0K
Pretax Income $-102M$-130M$-102M$-108M$-58M$-52M
Income Tax $4.0K$208.0K$134.0K$54.0K$292.0K$0
Net Income $-102M$-130M$-102M$-108M$-58M$-52M
EPS (Basic) $-0.87$-1.19$-1.08$-1.23$-0.94·
EPS (Diluted) $-0.87$-1.19$-1.08$-1.23$-0.94·
Shares (Basic) 116,166,187109,226,73194,572,44887,820,03762,108,032·
Shares (Diluted) 116,166,187109,226,73194,572,44887,820,03762,108,032·
EBITDA $-111M$-146M$-114M$-111M$-58M·
Balance Sheet 23
Metric Trend 202520242023202220212020
Cash & Equivalents $112M$70M$66M$60M$143M$28M
Short-term Investments $231M$188M$270M$306M$343M$162M
Receivables ···$2M$2M$2M
Prepaid Expense $10M$8M$9M$7M$5M$1M
Current Assets $354M$266M$347M$375M$492M$194M
PP&E (Net) $7M$8M$10M$11M$5M$4M
PP&E (Gross) $17M$16M$16M$15M$7M$6M
Accum. Depreciation $11M$8M$6M$4M$3M$2M
Other Non-current Assets $303.0K$4.0K$46.0K$5.0K$19.0K$38.0K
Total Assets $399M$316M$403M$436M$500M$207M
Accounts Payable $1M$2M$3M$4M$3M$2M
Accrued Liabilities ·····$74.9K
Current Liabilities $22M$38M$46M$56M$41M$41M
Capital Leases $31M$34M$37M$39M·$7M
Other Non-current Liabilities ·····$5.0K
Total Liabilities $53M$117M$149M$187M$155M$169M
Common Stock $136.0K$108.0K$102.0K$88.0K$88.0K$40.0K
Paid-in Capital $949M$701M$624M$523M$507M$142M
Retained Earnings $-603M$-502M$-371M$-270M$-161M$-103M
AOCI $224.0K$336.0K$186.0K$-4M$-765.0K$17.0K
Stockholders' Equity $346M$200M$253M$249M$345M$39M
Liabilities + Equity $399M$316M$403M$436M$500M$207M
Shares Outstanding 135,940,454107,729,343102,202,75988,179,37487,598,18440,372,133
Cash Flow 8
Metric Trend 202520242023202220212020
Stock-based Comp $26M$29M$19M$14M$8M$2M
Operating Cash Flow $-139M$-132M$-118M$-109M$-60M$70M
CapEx $1M$754.0K$2M$8M$2M$1M
Investing Cash Flow $-41M$86M$41M$26M$-183M$-145M
Financing Cash Flow $222M$48M$82M$2M$357M$81M
Net Change in Cash $43M$2M$6M$-81M$114M$5M
Taxes Paid $12.0K·····
Free Cash Flow $-140M$-132M$-120M$-117M$-61M·
Profitability 7
Metric Trend 202520242023202220212020
Operating Margin -178.4%-346.1%-312.6%-446.8%-157.1%·
Net Margin -162.8%-309.7%-278.5%-435.1%-157.2%·
Pretax Margin -162.8%-309.2%-278.2%-434.9%-156.4%·
EBITDA Margin -178.4%-346.1%-312.6%-446.8%-157.1%·
ROA -28.4%-36.2%-24.2%-23.1%-16.5%·
ROE -42.2%-60.8%-38.4%-41.4%-16.4%·
ROIC -32.1%-73.1%-45.2%-44.5%-17.0%·
Liquidity & Solvency 2
Metric Trend 202520242023202220212020
Current Ratio 16.37.07.56.812.113.1
Quick Ratio 15.86.87.36.612.011.5
Efficiency 2
Metric Trend 202520242023202220212020
Asset Turnover 0.20.10.10.10.1·
Receivables Turnover ···12.418.5·
Per Share 5
Metric Trend 202520242023202220212020
Book Value / Share $2.55$1.85$2.48$2.83$3.94$0.89
Revenue / Share $0.54$0.39$0.39$0.28··
Cash Flow / Share $-1.20$-1.20$-1.25$-1.24··
Cash / Share $0.83$0.65$0.65$0.68$1.63$0.23
EPS (TTM) $-0.87$-1.19$-1.08$-1.23$-0.94·
Growth Rates 3
Metric Trend 202520242023202220212020
Revenue YoY 48.3%15.2%46.9%-32.9%383.8%·
Revenue CAGR 3Y 35.9%4.3%68.3%···
Revenue CAGR 5Y 52.1%·····
Valuation (TTM) 10
Metric Trend 202520242023202220212020
Revenue TTM $62M$42M$37M$25M$37M$8M
Net Income TTM $-102M$-130M$-102M$-108M$-58M$-52M
Market Cap $1.20B$333M$1.01B$639M$958M$65M
P/E -10.2-2.6-9.2-5.9-11.6·
P/S 19.37.927.725.725.98.4
P/B 3.51.74.02.62.812.9
P / Tangible Book 3.51.74.02.62.81.7
P / Cash Flow -8.7-2.5-8.6-5.9-16.1·
P / FCF -8.6-2.5-8.5-5.5-15.6·
Earnings Yield -9.8%-38.5%-10.9%-17.0%-8.6%·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $62M $42M $37M $25M $37M
Operating Margin % -178.4% -346.1% -312.6% -446.8% -157.1%
Net Income $-102M $-130M $-102M $-108M $-58M
Diluted EPS $-0.87 $-1.19 $-1.08 $-1.23 $-0.94

Institutional owners (13F) 259 filers · $6.3B total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 259
Value held $6.3B
New positions 77
Exited positions 22
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
77 (+15 vs prior Q) 22 (-8 vs prior Q) 105 (+40 vs prior Q) 54 (0 vs prior Q) +38.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
RTW INVESTMENTS, LP $434,533,381 13,900,620 6.87% Shares
BlackRock, Inc. $388,825,760 12,438,444 6.15% Shares
FMR LLC $385,540,161 12,333,339 6.10% Shares
FARALLON CAPITAL MANAGEMENT, L.L.C. $383,779,020 12,277,000 6.07% Shares
Boxer Capital Management, LLC $339,990,606 10,876,219 5.38% Shares
GOLDMAN SACHS GROUP INC $311,994,191 9,980,620 4.94% Shares
TCG Crossover Management, LLC $283,878,343 9,081,201 4.49% Shares
Paradigm Biocapital Advisors LP $198,736,169 6,357,523 3.14% Shares
Siren, L.L.C. $193,166,919 6,179,364 3.06% Shares
STATE STREET CORP $186,928,736 5,979,806 2.96% Shares
VANGUARD CAPITAL MANAGEMENT LLC $186,226,699 5,957,348 2.95% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $175,056,000 5,600,000 2.77% Shares
Deep Track Capital, LP $131,292,000 4,200,000 2.08% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $130,998,500 4,190,611 2.07% Shares
Woodline Partners LP $125,057,724 4,000,567 1.98% Shares
TRV GP IV, LLC $120,181,383 6,374,574 1.90% Shares
GEODE CAPITAL MANAGEMENT, LLC $117,021,411 3,742,791 1.85% Shares
PERCEPTIVE ADVISORS LLC $105,565,020 3,377,000 1.67% Shares
Seven Fleet Capital Management LP $95,660,985 3,228,144 1.51% Shares
Logos Global Management LP $89,091,000 2,850,000 1.41% Shares
Caligan Partners LP $78,153,220 2,500,103 1.24% Shares
Holocene Advisors, LP $75,365,953 2,410,939 1.19% Shares
Commodore Capital LP $70,335,000 2,250,000 1.11% Shares
Balyasny Asset Management L.P. $63,032,008 2,016,379 1.00% Shares
Jefferies Financial Group Inc. $62,849,293 2,010,534 0.99% Shares
VANGUARD GROUP INC $59,813,655 6,750,977 0.95% Shares
FRANKLIN RESOURCES INC $58,994,217 1,887,211 0.93% Shares
Candriam S.C.A. $50,922,046 1,630,553 0.81% Shares
JANUS HENDERSON GROUP PLC $50,066,890 2,394,972 0.79% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $49,550,570 1,585,111 0.78% Shares
JPMORGAN CHASE & CO $46,318,195 1,418,193 0.73% Shares
Polar Capital Holdings Plc $46,287,932 1,480,740 0.73% Shares
Vivo Capital, LLC $43,131,579 1,379,769 0.68% Shares
DV EQUITIES, LLC $41,217,904 1,318,551 0.65% Shares
Cormorant Asset Management, LP $40,638,000 1,300,000 0.64% Shares
NORTHERN TRUST CORP $38,510,226 1,231,933 0.61% Shares
STEMPOINT CAPITAL LP $38,231,574 1,223,019 0.60% Shares
FEDERATED HERMES, INC. $37,968,802 1,214,613 0.60% Shares
VOYA INVESTMENT MANAGEMENT LLC $34,480,718 1,103,030 0.55% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $33,512,564 1,072,059 0.53% Shares
AMERICAN CENTURY COMPANIES INC $31,691,245 1,013,794 0.50% Shares
Integral Health Asset Management, LLC $31,260,000 1,000,000 0.49% Shares
VANGUARD FIDUCIARY TRUST CO $28,620,562 915,565 0.45% Shares
Nuveen, LLC $27,826,714 890,170 0.44% Shares
SAMLYN CAPITAL, LLC $23,959,946 766,473 0.38% Shares
RENAISSANCE TECHNOLOGIES LLC $23,391,858 748,300 0.37% Shares
Soleus Capital Management, L.P. $22,163,340 709,000 0.35% Shares
ArrowMark Colorado Holdings LLC $22,144,115 708,385 0.35% Shares
Bellevue Group AG $21,700,129 694,182 0.34% Shares
Alyeska Investment Group, L.P. $21,604,067 691,109 0.34% Shares

Show all 259 institutional owners →

Activists & 5%+ owners 5 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Third Rock Ventures IV, L.P., Third Rock Ventures GP IV, L.P., TRV GP IV, LLC ×3 filings Feb. 10, 2026 4.74% Amendment · SEC
BCTG Holdings, LLC, MVA Investors, LLC, Davis Aaron I., Boxer Capital Management, LLC ×7 filings Jan. 2, 2025 10.00% Amendment · SEC
Boxer Asset Management Inc., Braslyn Ltd., Joe Lewis Oct. 15, 2024 · Initial filing · SEC
Boxer Capital Management, LLC, Boxer Capital, LLC, MVA Investors, LLC, Aaron I. Davis Oct. 15, 2024 · Initial filing · SEC
Third Rock Ventures IV, L.P. (2), Third Rock Ventures GP IV, L.P. (2), TRV GP IV, LLC (2) ×2 filings Sept. 4, 2024 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 20 insiders · 9 officers · 9 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Malte Peters President & CEO Jan. 8, 2026 A 367,500 0 0 $0
Matthew Gall Chief Financial Officer May 1, 2026 A 40,000 0 0 $0
Daniella Beckman Chief Financial Officer Feb. 2, 2026 A 184,297 0 2 $-126,559
Adam Crystal President, R&D Sept. 1, 2026 M 115,743 0 16 $-6,328,368
Jessica Newcomb Principal Accounting Officer Sept. 22, 2026 S 59,121 0 3 $-198,615
Barbara Weber Director, Executive Chair Feb. 2, 2026 A 1,629,254 0 2 $-374,376
Douglas Barry General Counsel Feb. 5, 2025 S 66,014 0 0 $0
Alan Huang Chief Scientific Officer March 1, 2023 A 167,584 0 0 $0
Marc Rudoltz Chief Medical Officer Nov. 1, 2021 A · 0 0 $0
Robert Azelby Director June 19, 2026 A 5,740 0 0 $0
John B Ketchum Director June 5, 2026 A 24,937 0 0 $0
Mace Rothenberg Director June 5, 2026 A 41,500 0 0 $0
Sung Lee Director June 5, 2026 A 22,870 0 0 $0
Lesley Ann Calhoun Director June 5, 2026 A 16,500 0 0 $0
Alexis Borisy Director June 5, 2025 A 17,500 0 0 $0
Reid M Huber Director June 6, 2023 A 5,000 0 0 $0
EcoR1 Capital, LLC 10% owner Nov. 7, 2024 S 10,630,736 0 0 $0
Davis Aaron I. · Sept. 3, 2024 J 5,000 0 0 $0
Aaron Weitzman · Dec. 1, 2022 A · 0 0 $0
BCTG Holdings, LLC · Nov. 20, 2020 S 4,488,450 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 34 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PTH · Invesco Exchange-Traded Fund Trust 1.89% 278,445 SH Oct. 1, 2026 Daily
DWAS · Invesco Exchange-Traded Fund Trust … 1.26% 206,200 SH Oct. 1, 2026 Daily
BBC · ETFis Series Trust I 0.59% 10,046 NS July 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.54% 97,971 NS July 31, 2026 N-PORT
FYC · First Trust Exchange-Traded AlphaDE… 0.47% 224,575 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.28% 11,928 SH Oct. 1, 2026 Daily
VTWG · VANGUARD SCOTTSDALE FUNDS 0.26% 150,730 SH Aug. 19, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.23% 146,692 SH Aug. 19, 2026 Daily
FYX · First Trust Exchange-Traded AlphaDE… 0.22% 111,623 NS July 31, 2026 N-PORT
IWO · iShares Trust 0.22% 1,321,158 SH Sept. 11, 2026 Daily
IBB · iShares Trust 0.21% 910,926 SH Sept. 11, 2026 Daily
NUSC · Nushares ETF Trust 0.17% 80,173 NS July 31, 2026 N-PORT
PWS · Pacer Funds Trust 0.15% 1,338 NS July 31, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.13% 810,623 SH Aug. 19, 2026 Daily
RSSL · Global X Funds 0.12% 67,434 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.11% 3,600,624 SH Sept. 11, 2026 Daily
BKSE · BNY Mellon ETF Trust 0.10% 3,292 NS July 31, 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.10% 25,464 NS July 31, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.10% 20,345 NS July 31, 2026 N-PORT
ISCG · iShares Trust 0.07% 29,532 SH Sept. 11, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.06% 61,701 SH Oct. 1, 2026 Daily
ESML · iShares Trust 0.05% 59,086 SH Sept. 11, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.04% 1,418,754 SH Aug. 19, 2026 Daily
VHT · VANGUARD WORLD FUND 0.04% 281,272 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.04% 44,480 NS July 31, 2026 N-PORT
WSML · iShares Trust 0.02% 6,262 SH Sept. 11, 2026 Daily
DFAS · Dimensional ETF Trust 0.01% 61,068 NS July 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.01% 4,396,603 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.01% 11,571 SH Aug. 19, 2026 Daily
IWV · iShares Trust 0.00% 40,191 SH Sept. 11, 2026 Daily
ITOT · iShares Trust 0.00% 151,712 SH Sept. 11, 2026 Daily
DFAU · Dimensional ETF Trust 0.00% 4,480 NS July 31, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.00% 5,276 NS July 31, 2026 N-PORT
ISCB · iShares Trust · 4,243 SH Sept. 11, 2026 Daily

TNGX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 19 analysts BUY
Median target $40.00 +72.1%
8 42.1% Strong Buy
9 47.4% Buy
2 10.5% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

11 analysts · 2026-10-01

Mean target $45.18 +94.4%

← Below all targets Current price $23.24
Low$24.00 Mean$45.18 High$69.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
TNGX $1.20B -10.2 48.3% -162.8% -42.2% ·
ERAS $1.06B -8.5 · · -35.7% ·
DNTH $1.78B -9.8 -67.3% -7973.3% -40.8% ·
RLAY $1.47B -5.3 53.4% -1800.6% -44.9% ·
VKTX $4.04B -11.0 · · -47.3% ·
LEGN · -26.8 · · -29.1% ·
PBLS · · · · · ·
VCYT $3.34B 51.3 16.0% 12.8% 5.2% 70.1%
IDYA $3.04B -27.0 3024.4% -52.0% -11.5% ·

Latest News Recent headlines mentioning this company

23
Tango Therapeutics (TNGX) Could Benefit From Pancreatic Ductal Adenocarcinoma Data Announcement Yahoo Finance · 3 months, 4 weeks ago Stifel Remains Bullish on Tango Therapeutics (TNGX) Yahoo Finance · 4 months, 3 weeks ago

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 11, 2026