AMLX Amylyx Pharmaceuticals, Inc. - Common Stock
AMLX Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
AMLX Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
AMLX Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 8 47,1%
- Achat 7 41,2%
- Conserver 2 11,8%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
11 analystes · 2026-08-19Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.39 | $-0.37 | -0.02% |
| 31 mars 2026 | $-0.37 | $-0.34 | -0.03% |
| 31 décembre 2025 | $-0.30 | $-0.37 | 0.07% |
| 30 septembre 2025 | $-0.37 | $-0.46 | 0.09% |
| 30 juin 2025 | $-0.46 | $-0.45 | -0.01% |
| 31 mars 2025 | $-0.42 | $-0.48 | 0.06% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| AMLX | $1.33B | -7.9 | -77.1% | — | -61.2% | — |
| LGND | $3.74B | 30.8 | 60.4% | 46.4% | 13.5% | — |
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| MANE | — | — | — | — | 82.6% | — |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
| MBX | $1.42B | -13.3 | — | — | -29.6% | — |
| TARS | $3.48B | -51.5 | 146.7% | -14.7% | -19.7% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 16
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue | $0 | $87M | $381M | $22M | $285.0K | |
| Cost of Revenue | $0 | $6M | $25M | $3M | · | |
| R&D Expense | $90M | $104M | $128M | $93M | $44M | |
| SG&A Expense | $63M | $114M | $188M | $127M | $39M | |
| Operating Expenses | $153M | $402M | $342M | $224M | $83M | |
| Operating Income | $-153M | $-315M | $39M | $-201M | $-83M | |
| Interest Income | $9M | $14M | $16M | $4M | $36.0K | |
| Other Non-op | $-700.0K | $-1M | $-660.0K | $-551.0K | $-51.0K | |
| Pretax Income | $-145M | $-302M | $54M | $-198M | $-88M | |
| Income Tax | $46.0K | $-393.0K | $5M | $774.0K | · | |
| Net Income | $-145M | $-302M | $49M | $-198M | $-88M | |
| EPS (Basic) | $-1.53 | $-4.43 | $0.73 | $-3.39 | $-13.35 | |
| EPS (Diluted) | $-1.53 | $-4.43 | $0.70 | $-3.39 | $-13.35 | |
| Shares (Basic) | 94,565,567 | 68,142,158 | 67,234,465 | 58,495,587 | 6,586,349 | |
| Shares (Diluted) | 94,565,567 | 68,142,158 | 69,991,340 | 58,495,587 | 6,586,349 | |
| EBITDA | $-153M | $-315M | $39M | $-201M | · |
Bilan 22
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Cash & Equivalents | $227M | $77M | $170M | $63M | $50M | |
| Short-term Investments | $90M | $99M | $201M | $284M | $46M | |
| Receivables | $88.0K | $447.0K | $40M | $15M | · | |
| Inventory | · | · | $38M | $10M | · | |
| Prepaid Expense | $7M | $12M | $15M | $10M | $5M | |
| Current Assets | $324M | $189M | $465M | $382M | $105M | |
| PP&E (Net) | $310.0K | $961.0K | $3M | $3M | $474.0K | |
| PP&E (Gross) | $2M | $2M | $4M | $3M | $527.0K | |
| Accum. Depreciation | $2M | $1M | $2M | $540.0K | $53.0K | |
| Other Non-current Assets | $2M | $24.0K | $701.0K | $466.0K | · | |
| Total Assets | $333M | $194M | $517M | $391M | $106M | |
| Accounts Payable | $4M | $3M | $22M | $6M | $4M | |
| Accrued Liabilities | $18M | $24M | $58M | $38M | · | |
| Current Liabilities | $23M | $28M | $82M | $47M | $17M | |
| Capital Leases | $5M | $463.0K | $2M | $4M | · | |
| Total Liabilities | $27M | $29M | $84M | $51M | $17M | |
| Common Stock | $11.0K | $7.0K | $7.0K | $7.0K | $1.0K | |
| Retained Earnings | $-751M | $-607M | $-305M | $-354M | $-156M | |
| AOCI | $404.0K | $-92.0K | $197.0K | $-86.0K | $9.0K | |
| Stockholders' Equity | $305M | $165M | $433M | $341M | $-151M | |
| Liabilities + Equity | $333M | $194M | $517M | $391M | $106M | |
| Shares Outstanding | 109,884,502 | 68,629,738 | 67,707,432 | 66,512,011 | 7,020,487 |
Flux de trésorerie 9
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Stock-based Comp | $28M | $33M | $37M | $22M | $3M | |
| Restructuring | $0 | $23M | · | · | · | |
| Operating Cash Flow | $-123M | $-168M | $12M | $-180M | $-75M | |
| CapEx | $138.0K | $157.0K | $1M | $3M | $353.0K | |
| Investing Cash Flow | $14M | $76M | $92M | $-239M | $-46M | |
| Financing Cash Flow | $257M | $348.0K | $4M | $432M | $159M | |
| Net Change in Cash | $149M | $-92M | $108M | $13M | $37M | |
| Taxes Paid | $-1M | $235.0K | · | · | · | |
| Free Cash Flow | $-123M | $-168M | $11M | $-182M | · |
Rentabilité 7
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Operating Margin | · | -360.2% | 10.2% | -905.7% | · | |
| Net Margin | · | -345.4% | 12.9% | -892.4% | · | |
| Pretax Margin | · | -345.8% | 14.3% | -888.9% | · | |
| EBITDA Margin | · | -360.2% | 10.2% | -905.7% | · | |
| ROA | -55.0% | -84.9% | 10.8% | -79.8% | · | |
| ROE | -61.2% | -167.2% | 11.6% | -81.9% | · | |
| ROIC | -50.2% | -190.8% | 8.1% | -59.3% | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Current Ratio | 14.3 | 6.7 | 5.7 | 8.2 | · | |
| Quick Ratio | 14.0 | 6.2 | 5.0 | 7.8 | · |
Efficacité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.2 | 0.8 | 0.1 | · | |
| Inventory Turnover | · | · | 1.1 | 0.6 | · | |
| Receivables Turnover | 0.0 | 4.3 | 13.8 | 2.9 | · |
Taux de croissance 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue YoY | · | -77.1% | 1612.9% | 7700.0% | · | |
| Revenue CAGR 3Y | · | 574.3% | · | · | · |
Valorisation (TTM) 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $87M | $381M | $22M | $285.0K | |
| Net Income TTM | $-145M | $-302M | $49M | $-198M | $-88M | |
| Market Cap | $1.33B | $259M | $997M | $2.46B | · | |
| P/E | -7.9 | -0.9 | 21.0 | -10.9 | · | |
| P/S | · | 3.0 | 2.6 | 110.6 | · | |
| P/B | 4.3 | 1.6 | 2.3 | 7.2 | · | |
| P / Tangible Book | 4.3 | 1.6 | 2.3 | 7.2 | · | |
| P / Cash Flow | -10.8 | -1.5 | 83.6 | -13.7 | · | |
| P / FCF | -10.7 | -1.5 | 93.3 | -13.5 | · | |
| Earnings Yield | -12.7% | -117.2% | 4.8% | -9.2% | · |
Compte de résultat 16
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | $0 | $0 | $0 | $0 | $-665.0K | $416.0K | $-1M | $89M | $108M | $103M | $98M | $71M | $22M | $345.0K | |
| Cost of Revenue | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $8.0K | $6M | $9M | $5M | $6M | $5M | $3M | $172.0K | |
| R&D Expense | $24M | $28M | $21M | $20M | $27M | $22M | $23M | $21M | $23M | $37M | $45M | $30M | $29M | $24M | $23M | $25M | |
| SG&A Expense | $22M | $16M | $15M | $16M | $16M | $16M | $17M | $18M | $22M | $58M | $52M | $49M | $43M | $44M | $41M | $30M | |
| Operating Expenses | $46M | $44M | $37M | $36M | $43M | $38M | $40M | $76M | $75M | $211M | $107M | $84M | $78M | $73M | $66M | $55M | |
| Operating Income | $-46M | $-44M | $-37M | $-36M | $-43M | $-38M | $-41M | $-76M | $-76M | $-122M | $2M | $19M | $20M | $-2M | $-45M | $-55M | |
| Interest Income | $2M | $3M | $3M | $2M | $2M | $2M | $2M | $3M | $4M | $4M | $4M | $4M | $4M | $4M | $3M | $601.0K | |
| Other Non-op | $-53.0K | $-75.0K | $361.0K | $-180.0K | $-546.0K | $-335.0K | $157.0K | $-141.0K | $-483.0K | $-747.0K | $171.0K | $-488.0K | $-81.0K | $-262.0K | $-689.0K | $199.0K | |
| Pretax Income | · | · | $-33M | $-34M | $-41M | $-36M | $-38M | $-73M | $-73M | $-119M | $6M | $22M | $24M | $1M | $-42M | $-54M | |
| Income Tax | · | · | $46.0K | $0 | $0 | $0 | $-635.0K | $0 | $0 | $242.0K | $2M | $2M | $2M | $-170.0K | $579.0K | $-125.0K | |
| Net Income | $-43M | $-41M | $-33M | $-34M | $-41M | $-36M | $-38M | $-73M | $-73M | $-119M | $5M | $21M | $22M | $2M | $-43M | $-54M | |
| EPS (Basic) | $-0.39 | $-0.37 | $-0.28 | $-0.37 | $-0.46 | $-0.42 | $-0.54 | $-1.07 | $-1.07 | $-1.75 | $0.07 | $0.31 | $0.33 | $0.02 | $-0.61 | $-0.92 | |
| EPS (Diluted) | $-0.39 | $-0.37 | $-0.28 | $-0.37 | $-0.46 | $-0.42 | $-0.54 | $-1.07 | $-1.07 | $-1.75 | $0.07 | $0.30 | $0.31 | $0.02 | $-0.61 | $-0.92 | |
| Shares (Basic) | 111,196,883 | 110,563,360 | -173,603,039 | 93,332,930 | 89,138,568 | 85,697,108 | -135,828,573 | 68,091,446 | 68,024,929 | 67,854,356 | -134,131,092 | 67,414,669 | 67,233,617 | 66,717,271 | -109,917,852 | 58,533,226 | |
| Shares (Diluted) | 111,196,883 | 110,563,360 | -173,603,039 | 93,332,930 | 89,138,568 | 85,697,108 | -135,828,573 | 68,091,446 | 68,024,929 | 67,854,356 | -140,752,912 | 69,748,547 | 70,132,040 | 70,863,665 | -109,917,852 | 58,533,226 | |
| EBITDA | $-46M | $-44M | · | $-36M | $-43M | $-38M | · | $-76M | $-76M | $-122M | · | $19M | $20M | $-2M | · | $-55M |
Bilan 22
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $49M | $229M | $227M | $225M | $58M | $60M | $77M | $72M | $75M | $171M | $170M | $135M | $248M | $115M | $63M | $108M | |
| Short-term Investments | $201M | $51M | $90M | $119M | $123M | $144M | $99M | $163M | $235M | $203M | $201M | $220M | $110M | $231M | $284M | $55M | |
| Receivables | · | · | $88.0K | $132.0K | $103.0K | $300.0K | $447.0K | $2M | $4M | $20M | $40M | $29M | $33M | $18M | $15M | $137.0K | |
| Inventory | · | · | · | · | · | · | · | · | · | · | $38M | $32M | $25M | $13M | $10M | $563.0K | |
| Prepaid Expense | $6M | $5M | $7M | $9M | $6M | $12M | $12M | $9M | $13M | $17M | $15M | $17M | $12M | $13M | $10M | $8M | |
| Current Assets | $256M | $285M | $324M | $353M | $187M | $216M | $189M | $245M | $327M | $411M | $465M | $434M | $427M | $389M | $382M | $172M | |
| PP&E (Net) | $199.0K | $212.0K | $310.0K | $399.0K | $445.0K | $816.0K | $961.0K | $1M | $1M | $2M | $3M | $3M | $3M | $3M | $3M | $2M | |
| PP&E (Gross) | · | · | $2M | · | · | · | $2M | · | · | · | $4M | · | · | · | $3M | · | |
| Accum. Depreciation | · | · | $2M | · | · | · | $1M | · | · | · | $2M | · | · | · | $540.0K | · | |
| Other Non-current Assets | · | $2M | · | $2M | · | $11.0K | · | $482.0K | $479.0K | $493.0K | $701.0K | $476.0K | $466.0K | $466.0K | $466.0K | $456.0K | |
| Total Assets | $265M | $294M | $333M | $363M | $195M | $220M | $194M | $251M | $332M | $417M | $517M | $467M | $454M | $408M | $391M | $181M | |
| Accounts Payable | $6M | $4M | $4M | $5M | $3M | $5M | $3M | $1M | $5M | $21M | $22M | $6M | $25M | $11M | $6M | $7M | |
| Accrued Liabilities | $15M | $11M | $18M | $19M | $17M | $12M | $24M | $50M | $63M | $68M | $58M | $37M | $37M | $39M | $38M | · | |
| Current Liabilities | $21M | $16M | $23M | $26M | $21M | $18M | $28M | $54M | $70M | $92M | $82M | $46M | $64M | $52M | $47M | $33M | |
| Capital Leases | $4M | $4M | $5M | $5M | $5M | $327.0K | $463.0K | $595.0K | $772.0K | $1M | $2M | $3M | $3M | $4M | $4M | $5M | |
| Total Liabilities | $25M | $20M | $27M | $31M | $27M | $18M | $29M | $55M | $71M | $93M | $84M | $48M | $67M | $55M | $51M | $37M | |
| Common Stock | $11.0K | $11.0K | $11.0K | $11.0K | $9.0K | $9.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $7.0K | $6.0K | |
| Retained Earnings | $-836M | $-793M | $-751M | $-718M | $-684M | $-643M | $-607M | $-569M | $-496M | $-424M | $-305M | $-310M | $-331M | $-353M | $-354M | $-312M | |
| AOCI | $19.0K | $240.0K | $404.0K | $815.0K | $551.0K | $0 | $-92.0K | $641.0K | $-97.0K | $-77.0K | $197.0K | $-151.0K | $-72.0K | $25.0K | $-86.0K | $-725.0K | |
| Stockholders' Equity | $239M | $273M | $305M | $332M | $168M | $201M | $165M | $196M | $261M | $324M | $433M | $418M | $386M | $353M | $341M | $144M | |
| Liabilities + Equity | $265M | $294M | $333M | $363M | $195M | $220M | $194M | $251M | $332M | $417M | $517M | $467M | $454M | $408M | $391M | $181M | |
| Shares Outstanding | 111,368,283 | 111,026,477 | 109,884,502 | 109,766,382 | 89,156,350 | 89,080,821 | 68,629,738 | 68,545,508 | 68,079,057 | 67,975,587 | 67,707,432 | 67,505,126 | 67,354,417 | 67,095,603 | 66,512,011 | 58,533,226 |
Flux de trésorerie 9
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $8M | $6M | $6M | $7M | $7M | $7M | $7M | $7M | $10M | $10M | $10M | $10M | $10M | $8M | $6M | $6M | |
| Restructuring | · | · | $0 | $0 | $0 | · | $0 | $0 | $23M | · | · | · | · | · | · | · | |
| Operating Cash Flow | $-31M | $-37M | $-28M | $-30M | $-25M | $-40M | $-59M | $-42M | $-67M | $-489.0K | $14M | $-5M | $9M | $-5M | $-50M | $-43M | |
| CapEx | · | · | $86.0K | $24.0K | $17.0K | $11.0K | $20.0K | $-19.0K | $89.0K | $67.0K | $356.0K | $357.0K | $278.0K | $250.0K | $620.0K | $459.0K | |
| Investing Cash Flow | $-150M | $36M | $29M | $5M | $23M | $-44M | $65M | $39M | $-29M | $819.0K | $21M | $-108M | $123M | $56M | $-228M | $84M | |
| Financing Cash Flow | $1M | $3M | $-208.0K | $192M | $-31.0K | $66M | $110.0K | $80.0K | $27.0K | $131.0K | $230.0K | $889.0K | $1M | $1M | $232M | $0 | |
| Net Change in Cash | $-180M | $2M | $1M | $167M | $-2M | $-18M | $6M | $-2M | $-96M | $351.0K | $35M | $-113M | $133M | $52M | $-45M | $41M | |
| Taxes Paid | · | · | · | · | $-30.0K | $-30.0K | $499.0K | $17.0K | $-6.0K | $-275.0K | · | $-2M | · | · | · | · | |
| Free Cash Flow | · | · | · | · | · | $-40M | · | · | · | $-556.0K | · | · | · | $-5M | · | · |
Rentabilité 7
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | -18187.7% | 7457.1% | -137.8% | · | 18.2% | 20.6% | -2.9% | · | -15849.6% | |
| Net Margin | · | · | · | · | · | · | · | -17476.9% | 7106.6% | -134.0% | · | 20.3% | 22.5% | 2.2% | · | -15581.5% | |
| Pretax Margin | · | · | · | · | · | · | · | -17476.9% | 7106.6% | -133.7% | · | 21.8% | 24.4% | 2.0% | · | -15617.7% | |
| EBITDA Margin | · | · | · | · | · | · | · | -18187.7% | 7457.1% | -137.8% | · | 18.2% | 20.6% | -2.9% | · | -15849.6% | |
| ROA | -18.9% | -16.1% | · | -11.2% | -15.7% | -11.3% | · | -20.3% | -18.5% | -28.8% | · | 6.5% | 6.5% | 0.46% | · | -59.2% | |
| ROE | -21.3% | -17.4% | · | -13.0% | -19.3% | -13.7% | · | -23.7% | -22.4% | -35.1% | · | 7.4% | 7.6% | 0.53% | · | -74.7% | |
| ROIC | · | · | · | -10.8% | -25.5% | -18.8% | · | · | · | -37.7% | · | 4.2% | 4.8% | -0.65% | · | -37.9% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.1 | 17.9 | · | 13.7 | 8.7 | 12.1 | · | 4.5 | 4.7 | 4.5 | · | 9.5 | 6.7 | 7.5 | · | 5.3 | |
| Quick Ratio | 11.9 | 17.5 | · | 13.3 | 8.4 | 11.4 | · | 4.4 | 4.5 | 4.3 | · | 8.4 | 6.1 | 7.0 | · | 5.0 |
Efficacité 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | -0.0 | 0.2 | · | 0.3 | 0.3 | 0.2 | · | 0.0 | |
| Inventory Turnover | · | · | · | · | · | · | · | · | · | · | · | 0.3 | 0.4 | 0.8 | · | 0.6 | |
| Receivables Turnover | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 | -0.1 | 4.7 | · | 7.0 | 5.9 | 8.1 | · | 5.0 |
Valorisation (TTM) 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $416.0K | $416.0K | · | $416.0K | $-607.0K | $88M | · | $191M | $289M | $361M | · | $273M | · | · | · | · | |
| Net Income TTM | $-161M | $-153M | · | $-184M | $-223M | $-300M | · | $-243M | $-149M | $-74M | · | $-9M | $-84M | $-154M | · | $-179M | |
| Market Cap | $2.00B | $1.54B | · | $1.49B | $571M | $315M | · | $222M | $129M | $193M | · | $1.24B | $1.45B | $1.97B | · | $1.65B | |
| P/E | -11.3 | -8.6 | · | -5.9 | -2.1 | -0.8 | · | -0.9 | -0.9 | -2.5 | · | -63.1 | -14.2 | -10.6 | · | -4.5 | |
| P/S | 4808.1 | 3709.8 | · | 3585.9 | -941.5 | 3.6 | · | 1.2 | 0.4 | 0.5 | · | 4.5 | · | · | · | · | |
| P/B | 8.4 | 5.6 | · | 4.5 | 3.4 | 1.6 | · | 1.1 | 0.5 | 0.6 | · | 3.0 | 3.8 | 5.6 | · | 11.4 | |
| P / Tangible Book | 8.4 | 5.6 | · | 4.5 | 3.4 | 1.6 | · | 1.1 | 0.5 | 0.6 | · | 3.0 | 3.8 | 5.6 | · | 11.4 | |
| P / Cash Flow | · | -41.8 | · | · | · | -7.9 | · | · | · | -394.8 | · | · | · | -388.1 | · | · | |
| P / FCF | · | · | · | · | · | -7.9 | · | · | · | -347.2 | · | · | · | -369.9 | · | · | |
| Earnings Yield | -8.8% | -11.7% | · | -17.1% | -47.1% | -121.8% | · | -110.8% | -116.3% | -39.4% | · | -1.6% | -7.0% | -9.4% | · | -22.0% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Revenu | $0 | $87M | $381M | $22M | $285.0K |
| Marge d'exploitation % | — | -360.2% | 10.2% | -905.7% | — |
| Résultat net | $-145M | $-302M | $49M | $-198M | $-88M |
| BPA dilué | $-1.53 | $-4.43 | $0.70 | $-3.39 | $-13.35 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 14.3 | 6.7 | 5.7 | 8.2 | — |
| Ratio de liquidité réduite | 14.0 | 6.2 | 5.0 | 7.8 | — |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-123M | $-168M | $11M | $-182M | — |
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Détenteurs institutionnels (13F) 229 déclarants · $1.6B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 63 (+31 vs T. préc.) | 13 (-20 vs T. préc.) | 67 (0 vs T. préc.) | 63 (+12 vs T. préc.) | -2.3M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $261 703 547 | 14 571 467 | 16,32% | Actions |
| PERCEPTIVE ADVISORS LLC | $149 694 481 | 8 334 882 | 9,34% | Actions |
| TCG Crossover Management, LLC | $112 138 864 | 6 243 812 | 6,99% | Actions |
| Commodore Capital LP | $101 474 000 | 5 650 000 | 6,33% | Actions |
| Saturn V Capital Management LP | $83 048 854 | 4 624 101 | 5,18% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $75 867 063 | 4 224 224 | 4,73% | Actions |
| VANGUARD GROUP INC | $61 683 971 | 5 106 289 | 3,85% | Actions |
| Driehaus Capital Management LLC | $54 543 981 | 3 036 970 | 3,40% | Actions |
| First Light Asset Management, LLC | $54 297 678 | 3 023 256 | 3,39% | Actions |
| STATE STREET CORP | $46 755 933 | 2 603 337 | 2,92% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $36 185 723 | 2 014 412 | 2,26% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $34 124 000 | 1 900 000 | 2,13% | Actions |
| GOLDMAN SACHS GROUP INC | $27 615 512 | 1 537 612 | 1,72% | Actions |
| Siren, L.L.C. | $26 591 325 | 1 480 586 | 1,66% | Actions |
| EVENTIDE ASSET MANAGEMENT, LLC | $23 844 428 | 1 327 536 | 1,49% | Actions |
| 683 Capital Management, LLC | $22 980 036 | 1 279 512 | 1,43% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $19 065 151 | 1 061 534 | 1,19% | Actions |
| Alyeska Investment Group, L.P. | $18 912 149 | 1 053 015 | 1,18% | Actions |
| Almitas Capital LLC | $17 508 863 | 974 881 | 1,09% | Actions |
| Jones Hill Capital LP | $16 057 282 | 894 058 | 1,00% | Actions |
| Woodline Partners LP | $15 201 111 | 846 387 | 0,95% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $14 544 870 | 809 848 | 0,91% | Actions |
| Boxer Capital Management, LLC | $14 368 000 | 800 000 | 0,90% | Actions |
| Aberdeen Group plc | $13 248 553 | 737 670 | 0,83% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $13 021 539 | 725 030 | 0,81% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $12 949 196 | 721 002 | 0,81% | Actions |
| GREAT POINT PARTNERS LLC | $12 572 000 | 700 000 | 0,78% | Actions |
| Balyasny Asset Management L.P. | $12 302 133 | 684 974 | 0,77% | Actions |
| Qube Research & Technologies Ltd | $12 237 746 | 681 389 | 0,76% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $11 190 481 | 623 078 | 0,70% | Actions |
| TWO SIGMA INVESTMENTS, LP | $10 658 093 | 593 435 | 0,66% | Actions |
| BANK OF AMERICA CORP /DE/ | $9 650 357 | 537 325 | 0,60% | Actions |
| Rock Springs Capital Management LP | $8 975 761 | 499 764 | 0,56% | Actions |
| ADAR1 Capital Management, LLC | $8 879 029 | 494 378 | 0,55% | Actions |
| Nantahala Capital Management, LLC | $8 740 845 | 486 684 | 0,55% | Actions |
| Nearwater Capital Markets, Ltd | $7 633 000 | 425 000 | 0,48% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $7 279 188 | 405 300 | 0,45% | Option d'achat |
| Parkman Healthcare Partners LLC | $7 162 125 | 398 782 | 0,45% | Actions |
| HighVista Strategies LLC | $6 933 997 | 386 080 | 0,43% | Actions |
| STEMPOINT CAPITAL LP | $6 902 100 | 384 304 | 0,43% | Actions |
| Logos Global Management LP | $6 286 000 | 350 000 | 0,39% | Actions |
| Trexquant Investment LP | $6 275 924 | 349 439 | 0,39% | Actions |
| Ensign Peak Advisors, Inc | $5 485 720 | 305 441 | 0,34% | Actions |
| Tetragon Partners GP Ltd | $5 350 751 | 297 926 | 0,33% | Actions |
| JUPITER ASSET MANAGEMENT LTD | $4 937 994 | 274 944 | 0,31% | Actions |
| FIRST TRUST ADVISORS LP | $4 572 382 | 254 587 | 0,29% | Actions |
| JANE STREET GROUP, LLC | $4 338 992 | 241 592 | 0,27% | Actions |
| SummitTX Capital, L.P. | $4 089 312 | 227 690 | 0,26% | Actions |
| TWO SIGMA ADVISERS, LP | $3 967 084 | 328 401 | 0,25% | Actions |
| Cormorant Asset Management, LP | $3 592 000 | 200 000 | 0,22% | Actions |
| Aldebaran Capital, LLC | $3 518 220 | 195 892 | 0,22% | Actions |
| Walleye Capital LLC | $3 351 120 | 186 588 | 0,21% | Actions |
| ORBIMED ADVISORS LLC | $3 293 864 | 183 400 | 0,21% | Actions |
| BlackRock, Inc. | $3 211 122 | 178 793 | 0,20% | Actions |
| ACUTA CAPITAL PARTNERS, LLC | $3 019 345 | 168 115 | 0,19% | Actions |
| NORGES BANK | $2 871 804 | 159 900 | 0,18% | Actions |
| Alpha Wave Global, LP | $2 791 379 | 155 422 | 0,17% | Actions |
| Swiss National Bank | $2 589 832 | 144 200 | 0,16% | Actions |
| PFM Health Sciences, LP | $2 580 852 | 143 700 | 0,16% | Actions |
| AMERIPRISE FINANCIAL INC | $2 253 693 | 125 484 | 0,14% | Actions |
| Lighthouse Investment Partners, LLC | $2 207 446 | 122 909 | 0,14% | Actions |
| Ikarian Capital, LLC | $2 110 301 | 117 500 | 0,13% | Actions |
| RHUMBLINE ADVISERS | $2 028 032 | 112 920 | 0,13% | Actions |
| ALPS ADVISORS INC | $2 019 548 | 112 447 | 0,13% | Actions |
| Elmind Capital, LP | $2 011 520 | 112 000 | 0,13% | Actions |
| Campbell & CO Investment Adviser LLC | $1 813 295 | 100 963 | 0,11% | Actions |
| Affinity Asset Advisors, LLC | $1 778 022 | 98 999 | 0,11% | Actions |
| Bank of New York Mellon Corp | $1 759 164 | 97 949 | 0,11% | Actions |
| 683 Capital Management, LLC | $1 734 936 | 96 600 | 0,11% | Option d'achat |
| Quantinno Capital Management LP | $1 452 066 | 80 850 | 0,09% | Actions |
| ALLIANCEBERNSTEIN L.P. | $1 451 160 | 104 400 | 0,09% | Actions |
| 1492 Capital Management LLC | $1 432 328 | 79 751 | 0,09% | Actions |
| JPMORGAN CHASE & CO | $1 325 363 | 70 875 | 0,08% | Actions |
| CITADEL ADVISORS LLC | $1 206 409 | 67 172 | 0,08% | Actions |
| Schonfeld Strategic Advisors LLC | $1 199 799 | 66 804 | 0,07% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $1 195 382 | 66 558 | 0,07% | Actions |
| CITIGROUP INC | $1 138 251 | 63 377 | 0,07% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 100 553 | 61 278 | 0,07% | Actions |
| JANE STREET GROUP, LLC | $1 079 396 | 60 100 | 0,07% | Option de vente |
| Corient Private Wealth LP | $1 065 424 | 59 322 | 0,07% | Actions |
| Moody Aldrich Partners LLC | $1 038 124 | 57 802 | 0,06% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $1 022 786 | 56 948 | 0,06% | Actions |
| MetLife Investment Management, LLC | $1 000 372 | 55 700 | 0,06% | Actions |
| D. E. Shaw & Co., Inc. | $979 485 | 54 537 | 0,06% | Actions |
| BARCLAYS PLC | $968 350 | 53 917 | 0,06% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $903 528 | 65 002 | 0,06% | Actions |
| FEDERATED HERMES, INC. | $903 478 | 50 305 | 0,06% | Actions |
| Hudson Bay Capital Management LP | $898 000 | 50 000 | 0,06% | Actions |
| Vanguard Global Advisers, LLC | $859 404 | 47 851 | 0,05% | Actions |
| FOX RUN MANAGEMENT, L.L.C. | $804 913 | 44 817 | 0,05% | Actions |
| Allostery Investments LP | $769 963 | 120 119 | 0,05% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $760 624 | 42 351 | 0,05% | Actions |
| ADAR1 Capital Management, LLC | $720 196 | 40 100 | 0,04% | Option de vente |
| Aquatic Capital Management LLC | $708 073 | 39 425 | 0,04% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $679 391 | 37 828 | 0,04% | Actions |
| Invesco Ltd. | $660 443 | 36 773 | 0,04% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $647 638 | 36 060 | 0,04% | Actions |
| JENNISON ASSOCIATES LLC | $643 705 | 35 841 | 0,04% | Actions |
| TUDOR INVESTMENT CORP ET AL | $635 964 | 35 410 | 0,04% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $616 028 | 34 300 | 0,04% | Actions |
Initiés de la société 15 initiés · 7 dirigeants · 8 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Joshua B Cohen | Co-Chief Executive Officer | 5 mars 2026 A | 3 583 548 | 0 | 7 | $-3 044 636 |
| Justin B. Klee | Co-Chief Executive Officer | 5 mars 2026 A | 3 583 481 | 0 | 7 | $-3 044 891 |
| James M Frates | Chief Financial Officer | 5 mars 2026 A | 261 628 | 0 | 4 | $-358 576 |
| Gina Mazzariello | Chief Legal Officer | 10 juillet 2026 S | 179 090 | 0 | 6 | $-865 895 |
| Camille L Bedrosian | Chief Medical Officer | 5 mars 2026 A | 265 285 | 0 | 3 | $-364 153 |
| Patrick D Yeramian | Chief Medical Officer | 9 janvier 2024 S | 205 605 | 0 | 0 | $0 |
| Margaret Olinger | Chief Commercial Officer | 27 décembre 2023 M | 276 108 | 0 | 0 | $0 |
| Bernhardt G Zeiher | Administrateur | 4 juin 2026 A | 10 000 | 0 | 0 | $0 |
| Karen Firestone | Administrateur | 4 juin 2026 A | 66 900 | 2 | 0 | $152 183 |
| Paul R. Fonteyne | Administrateur | 4 juin 2026 A | 3 947 | 0 | 0 | $0 |
| Daphne Quimi | Administrateur | 4 juin 2026 A | 5 000 | 0 | 0 | $0 |
| George M Milne JR | Administrateur | 4 juin 2026 A | 812 881 | 0 | 0 | $0 |
| Isaac Cheng | Administrateur | 9 juin 2022 A | 6 578 | 0 | 0 | $0 |
| Morningside Venture Investments Ltd | Détenteur de 10% | 15 août 2023 G | 4 997 302 | 0 | 0 | $0 |
| ALS Invest 1 B.V. | Détenteur de 10% | 6 juillet 2022 S | 5 895 280 | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 1 participation
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Morningside Venture Investments Limited (2), MVIL, LLC (2), Frances Anne Elizabeth Richard (2), Jill Marie Franklin (2), Peter Stuart Allenby Edwards (2), Cheung Ka Ho (2), Cheng Yee Wing Betty (2), Wong See Wai (2) ×5 dépôts | 4 octobre 2023 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 50 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| PILL · Direxion Shares ETF Trust | 1,43% | 11 556 NS | 30 avril 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 1,01% | 113 933 NS | 31 mai 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,90% | 21 068 NS | 30 avril 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 0,82% | 23 554 NS | 31 mai 2026 | N-PORT |
| FYC · First Trust Exchange-Traded AlphaDE… | 0,26% | 168 022 NS | 30 avril 2026 | N-PORT |
| FSCC · Federated Hermes ETF Trust | 0,25% | 47 310 NS | 31 mai 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,10% | 82 935 NS | 30 avril 2026 | N-PORT |
| ESSC · Strategy Shares | 0,10% | 1 602 NS | 30 avril 2026 | N-PORT |
| NUSC · Nushares ETF Trust | 0,09% | 69 649 NS | 30 avril 2026 | N-PORT |
| BIB · ProShares Trust | 0,08% | 4 059 NS | 31 mai 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,07% | 30 496 NS | 30 avril 2026 | N-PORT |
| FYX · First Trust Exchange-Traded AlphaDE… | 0,07% | 49 811 NS | 30 avril 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,06% | 43 655 NS | 31 mai 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,05% | 15 666 NS | 30 avril 2026 | N-PORT |
| RSSL · Global X Funds | 0,04% | 39 313 NS | 30 avril 2026 | N-PORT |
| ITWO · ProShares Trust | 0,03% | 4 300 NS | 31 mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,03% | 402 853 NS | 31 mai 2026 | N-PORT |
| UWM · ProShares Trust | 0,02% | 3 363 NS | 31 mai 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,02% | 150 411 NS | 30 avril 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,02% | 30 218 NS | 30 avril 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 3 404 NS | 31 mai 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 3 710 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 85 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 39 887 NS | 31 mai 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 4 500 NS | 30 avril 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 54 057 NS | 30 avril 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 58 783 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 13 188 NS | 30 avril 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 8 949 NS | 30 avril 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 8 NS | 30 avril 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTI · VANGUARD INDEX FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | — | — | 30 juillet 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 15 juillet 2026 | Quotidien |
| ITOT · iShares Trust | — | — | 5 août 2026 | Quotidien |
| IWV · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWO · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IWM · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IBB · iShares Trust | — | — | 18 août 2026 | Quotidien |
| IHE · iShares Trust | — | — | 18 août 2026 | Quotidien |
| PRFZ · Invesco Exchange-Traded Fund Trust | — | — | 23 juillet 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | — | — | 20 juillet 2026 | Quotidien |
| ISCB · iShares Trust | — | — | 5 août 2026 | Quotidien |
| ISCV · iShares Trust | — | — | 5 août 2026 | Quotidien |
| SMLF · iShares Trust | — | — | 10 août 2026 | Quotidien |
| ESML · iShares Trust | — | — | 14 août 2026 | Quotidien |
| WSML · iShares Trust | — | — | 5 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | — | — | 20 juillet 2026 | Quotidien |