ELVN Enliven Therapeutics, Inc. - Common Stock
ELVN Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
ELVN Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
ELVN Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 7 38,9%
- Achat 10 55,6%
- Conserver 1 5,6%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
9 analystes · 2026-08-17Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-0.49 | $-0.41 | -0.08% |
| 31 mars 2026 | $-0.38 | $-0.47 | 0.09% |
| 31 décembre 2025 | $-0.48 | $-0.39 | -0.09% |
| 30 septembre 2025 | $-0.32 | $-0.44 | 0.12% |
| 30 juin 2025 | $-0.49 | $-0.54 | 0.05% |
| 31 mars 2025 | $-0.57 | $-0.51 | -0.06% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| AMRX | — | 57.3 | 8.1% | 2.4% | -80.0% | 36.9% |
| LGND | $3.74B | 30.8 | 60.4% | 46.4% | 13.5% | — |
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| MANE | — | — | — | — | 82.6% | — |
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
| MBX | $1.42B | -13.3 | — | — | -29.6% | — |
| ALMS | — | -3.4 | — | -1011.8% | -61.9% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 13
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $86M | $81M | $65M | $31M | $38M | $32M | $19M | |
| SG&A Expense | $34M | $24M | $19M | $8M | $13M | $10M | $5M | |
| Operating Expenses | $120M | $105M | $84M | $39M | $51M | $42M | $24M | |
| Operating Income | $-120M | $-105M | $-84M | $-39M | $-51M | $-42M | $-24M | |
| Other Non-op | $-49.0K | $-2.0K | $-22.0K | $0 | $-175.0K | $-145.0K | $75.0K | |
| Pretax Income | · | · | · | $2M | $-51M | · | · | |
| Income Tax | $0 | $232.0K | $0 | $0 | · | · | · | |
| Net Income | $-104M | $-89M | $-72M | $-38M | $-51M | $-41M | $-23M | |
| EPS (Basic) | $-1.83 | $-1.89 | $-2.01 | $-12.05 | $-2.37 | · | · | |
| EPS (Diluted) | $-1.83 | $-1.89 | $-2.01 | $-12.05 | $-2.37 | · | · | |
| Shares (Basic) | 56,664,226 | 47,072,532 | 35,546,215 | 3,124,274 | 21,661,450 | · | · | |
| Shares (Diluted) | 56,664,226 | 47,072,532 | 35,546,215 | 3,124,274 | 21,661,450 | · | · | |
| EBITDA | $-119M | $-104M | $-83M | $730.0K | $-51M | $-42M | · |
Bilan 22
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $99M | $124M | $100M | $76M | $48M | $48M | $5M | |
| Short-term Investments | $364M | $189M | $153M | $0 | · | · | · | |
| Prepaid Expense | $12M | $5M | $3M | $2M | $2M | $2M | $2M | |
| Current Assets | $475M | $318M | $266M | $78M | $93M | $90M | $31M | |
| PP&E (Net) | $34.0K | $458.0K | $742.0K | $890.0K | $250.0K | $349.0K | $442.0K | |
| PP&E (Gross) | $263.0K | $1M | $1M | $1M | $479.0K | $479.0K | $475.0K | |
| Accum. Depreciation | $229.0K | $919.0K | $671.0K | $374.0K | $229.0K | $130.0K | $33.0K | |
| Other Non-current Assets | $656.0K | $7M | $4M | $0 | $175.0K | $88.0K | $2M | |
| Total Assets | $476M | $326M | $272M | $83M | $94M | $91M | $33M | |
| Accounts Payable | $2M | $1M | $532.0K | $3M | $2M | $2M | $2M | |
| Accrued Liabilities | · | · | · | $2M | $5M | $4M | $3M | |
| Current Liabilities | $17M | $16M | $26M | $10M | $7M | $6M | $4M | |
| Capital Leases | $0 | · | $0 | · | $406.0K | · | · | |
| Other Non-current Liabilities | $0 | $0 | $67.0K | $659.0K | · | · | · | |
| Total Liabilities | $17M | $16M | $26M | $10M | $8M | $6M | $4M | |
| Common Stock | $59.0K | $49.0K | $41.0K | $1.0K | $27.0K | $18.0K | $1.0K | |
| Paid-in Capital | $806M | $553M | $400M | $6M | $234M | $181M | $6M | |
| Retained Earnings | $-347M | $-243M | $-154M | $-83M | $-147M | $-96M | $-55M | |
| AOCI | $334.0K | $55.0K | $141.0K | $0 | $-16.0K | $4.0K | $32.0K | |
| Stockholders' Equity | $460M | $310M | $246M | $-77M | $-43M | $84M | $-49M | |
| Liabilities + Equity | $476M | $326M | $272M | $83M | $94M | $91M | $33M | |
| Shares Outstanding | 59,440,045 | 48,936,459 | 41,292,027 | 3,570,019 | 26,287,264 | 17,548,263 | 702,510 |
Flux de trésorerie 11
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $300.0K | $300.0K | $300.0K | $200.0K | · | · | · | |
| Stock-based Comp | $34M | $20M | $13M | $3M | $4M | $2M | $899.0K | |
| Other Non-cash | $-926.0K | $-5M | $-3M | · | · | · | · | |
| Operating Cash Flow | $-70M | $-73M | $-61M | $-32M | $-47M | $-37M | $-22M | |
| CapEx | $158.0K | $44.0K | $149.0K | $612.0K | $12.0K | $18.0K | $140.0K | |
| Investing Cash Flow | $-174M | $-36M | $-148M | $-612.0K | $-2M | $-17M | $-24M | |
| Stock Issued | · | $0 | $161M | $0 | · | · | · | |
| Net Stock Activity | · | $0 | $161M | · | · | · | · | |
| Financing Cash Flow | $219M | $133M | $234M | $-2M | $49M | $97M | $44M | |
| Taxes Paid | $0 | $209.0K | · | · | · | · | · | |
| Free Cash Flow | $-70M | $-73M | $-61M | $-36M | $-47M | $-37M | · |
Rentabilité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -25.9% | -29.8% | -40.3% | 1.6% | -55.7% | -66.6% | · | |
| ROE | -21.9% | -29.8% | -28.2% | 13.5% | -55.4% | -46.2% | · | |
| ROIC | · | · | · | 0.76% | · | · | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 28.7 | 20.0 | 10.3 | 49.0 | 12.9 | 14.5 | · | |
| Quick Ratio | 27.9 | 19.7 | 9.8 | 48.2 | 6.7 | 7.6 | · |
Valorisation (TTM) 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-104M | $-89M | $-72M | $-38M | $-51M | $-41M | · | |
| Market Cap | $915M | $1.10B | $571M | $430M | $237M | $1.55B | · | |
| P/E | -8.4 | -11.9 | -6.9 | -1.4 | -3.8 | · | · | |
| P/B | 2.0 | 3.6 | 2.3 | 4.8 | 2.8 | 18.3 | · | |
| P / Tangible Book | 2.0 | 3.6 | 2.3 | · | · | 18.3 | · | |
| P / Cash Flow | -13.0 | -15.0 | -9.3 | -12.1 | -5.1 | -41.4 | · | |
| P / FCF | -13.0 | -15.0 | -9.3 | -12.0 | -5.1 | -41.4 | · | |
| Earnings Yield | -11.9% | -8.4% | -14.5% | -73.7% | -26.3% | · | · |
Compte de résultat 12
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $29M | $21M | $21M | $18M | $21M | $25M | $21M | $21M | $19M | $20M | $18M | $20M | $15M | $12M | $8M | $8M | |
| SG&A Expense | $8M | $7M | $13M | $7M | $7M | $7M | $6M | $6M | $6M | $6M | $5M | $5M | $5M | $5M | $2M | $3M | |
| Operating Expenses | $37M | $28M | $34M | $25M | $29M | $32M | $27M | $27M | $25M | $26M | $23M | $24M | $20M | $16M | $10M | $11M | |
| Operating Income | $-37M | $-28M | $-34M | $-25M | $-29M | $-32M | $-27M | $-27M | $-25M | $-26M | $-23M | $-24M | $-20M | $-16M | $-10M | $-11M | |
| Other Non-op | $-8.0K | $0 | $0 | $0 | $-2.0K | $-47.0K | $0 | $0 | $-1.0K | $-1.0K | $-9.0K | $-13.0K | $0 | $0 | $-136.0K | $0 | |
| Income Tax | · | · | $0 | $0 | $0 | · | $0 | $0 | $232.0K | · | $0 | $0 | · | · | · | · | |
| Net Income | $-32M | $-24M | $-30M | $-20M | $-25M | $-29M | $-23M | $-23M | $-20M | $-23M | $-19M | $-21M | $-17M | $-15M | $-10M | $-11M | |
| EPS (Basic) | $-0.49 | $-0.38 | $-0.45 | $-0.32 | $-0.49 | $-0.57 | $-0.46 | $-0.48 | $-0.41 | $-0.54 | $-0.29 | $-0.51 | $-0.41 | $-0.80 | $-2.91 | $-3.27 | |
| EPS (Diluted) | $-0.49 | $-0.38 | $-0.45 | $-0.32 | $-0.49 | $-0.57 | $-0.46 | $-0.48 | $-0.41 | $-0.54 | $-0.29 | $-0.51 | $-0.41 | $-0.80 | $-2.91 | $-3.27 | |
| Shares (Basic) | 66,171,581 | 62,799,326 | -107,585,904 | 62,093,795 | 52,105,052 | 50,051,283 | -91,315,569 | 48,267,458 | 48,075,035 | 42,045,608 | -87,406,707 | 41,030,874 | 40,961,024 | 40,961,024 | -6,085,171 | 3,228,692 | |
| Shares (Diluted) | 66,171,581 | 62,799,326 | -107,585,904 | 62,093,795 | 52,105,052 | 50,051,283 | -91,315,569 | 48,267,458 | 48,075,035 | 42,045,608 | -87,406,707 | 41,030,874 | 40,961,024 | 40,961,024 | -6,085,171 | 3,228,692 | |
| EBITDA | $-37M | $-28M | · | $-25M | $-29M | $-32M | · | $-27M | $-25M | $-26M | · | $-24M | $-20M | $51M | · | $-5M |
Bilan 22
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $136M | $132M | $99M | $102M | $119M | $102M | $124M | $101M | $97M | $149M | $100M | $74M | $126M | $292M | $76M | $49M | |
| Short-term Investments | $760M | $320M | $364M | $376M | $371M | $188M | $189M | $191M | $216M | $171M | $153M | $190M | $152M | · | $0 | · | |
| Prepaid Expense | $12M | $11M | $12M | $5M | $5M | $5M | $5M | $5M | $6M | $7M | $3M | $5M | $5M | $6M | $2M | $3M | |
| Current Assets | $907M | $463M | $475M | $483M | $496M | $294M | $318M | $297M | $318M | $337M | $266M | $269M | $283M | $298M | $78M | $59M | |
| PP&E (Net) | $140.0K | $20.0K | $34.0K | $399.0K | $462.0K | $404.0K | $458.0K | $549.0K | $630.0K | $683.0K | $742.0K | $806.0K | $867.0K | $853.0K | $890.0K | · | |
| PP&E (Gross) | $390.0K | · | $263.0K | $2M | $2M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | · | |
| Accum. Depreciation | $250.0K | $243.0K | $229.0K | $1M | $1M | $993.0K | $919.0K | $908.0K | $828.0K | $750.0K | $671.0K | $593.0K | $515.0K | $441.0K | $374.0K | · | |
| Other Non-current Assets | $1M | $1M | $656.0K | $7M | $7M | $7M | $7M | $7M | $8M | $4M | $4M | $4M | $3M | $3M | $0 | · | |
| Total Assets | $910M | $465M | $476M | $491M | $504M | $303M | $326M | $305M | $327M | $343M | $272M | $274M | $289M | $303M | $83M | $59M | |
| Accounts Payable | $371.0K | $2M | $2M | $1M | $2M | $2M | $1M | $1M | $1M | $3M | $532.0K | $1M | $3M | $6M | $3M | $767.0K | |
| Accrued Liabilities | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $1M | |
| Current Liabilities | $14M | $11M | $17M | $15M | $15M | $14M | $16M | $17M | $22M | $25M | $26M | $12M | $9M | $11M | $10M | $2M | |
| Capital Leases | $913.0K | $0 | $0 | $103.0K | $204.0K | $302.0K | · | $0 | $0 | $0 | · | $81.0K | $162.0K | $242.0K | · | · | |
| Other Non-current Liabilities | $913.0K | · | · | $103.0K | $204.0K | $302.0K | · | $0 | $6.0K | $34.0K | $67.0K | $214.0K | $360.0K | $508.0K | $659.0K | · | |
| Total Liabilities | $15M | $11M | $17M | $15M | $15M | $14M | $16M | $17M | $22M | $25M | $26M | $12M | $10M | $11M | $10M | $2M | |
| Common Stock | $73.0K | $61.0K | $59.0K | $59.0K | $59.0K | $49.0K | $49.0K | $47.0K | $47.0K | $47.0K | $41.0K | $41.0K | $41.0K | $41.0K | $1.0K | $27.0K | |
| Paid-in Capital | $1.30B | $824M | $806M | $793M | $786M | $560M | $553M | $508M | $502M | $495M | $400M | $397M | $393M | $389M | $6M | $235M | |
| Retained Earnings | $-403M | $-371M | $-347M | $-317M | $-297M | $-272M | $-243M | $-220M | $-197M | $-177M | $-154M | $-135M | $-114M | $-98M | $-83M | $-178M | |
| AOCI | $-2M | $-382.0K | $334.0K | $221.0K | $-177.0K | $-16.0K | $55.0K | $242.0K | $-139.0K | $-53.0K | $141.0K | $-147.0K | $-111.0K | · | $0 | $-4.0K | |
| Stockholders' Equity | $895M | $453M | $460M | $476M | $488M | $288M | $310M | $288M | $305M | $318M | $246M | $262M | $279M | $291M | $-77M | $57M | |
| Liabilities + Equity | $910M | $465M | $476M | $491M | $504M | $303M | $326M | $305M | $327M | $343M | $272M | $274M | $289M | $303M | $83M | $59M | |
| Shares Outstanding | 73,251,648 | 60,889,655 | 59,440,045 | 59,261,286 | 59,226,171 | 49,038,730 | 48,936,459 | 47,254,280 | 47,173,466 | 46,782,639 | 41,292,027 | 41,204,973 | 41,151,111 | 41,106,277 | 3,570,019 | 26,287,264 |
Flux de trésorerie 11
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $7.0K | $14.0K | $83.0K | $62.0K | $81.0K | $74.0K | $62.0K | $80.0K | $79.0K | $79.0K | $80.0K | $79.0K | $74.0K | $67.0K | $-39M | $60.0K | |
| Stock-based Comp | $14M | $7M | $12M | $7M | $8M | $7M | $5M | $5M | $5M | $5M | $3M | $3M | $4M | $2M | $735.0K | $1M | |
| Other Non-cash | · | $-3M | · | · | · | $-2M | · | · | · | $-5M | · | · | · | $-75M | · | · | |
| Operating Cash Flow | $-19M | $-19M | $-16M | $-13M | $-17M | $-24M | $-17M | $-12M | $-20M | $-23M | $-12M | $-16M | $-12M | $-21M | $-8M | $6M | |
| CapEx | $99.0K | $0 | $0 | $-1.0K | $139.0K | $20.0K | $0 | $22.0K | $2.0K | $20.0K | $14.0K | $16.0K | $88.0K | $31.0K | $101.0K | $169.0K | |
| Investing Cash Flow | $-442M | $43M | $12M | $-4M | $-184M | $1M | $727.0K | $15M | $-34M | $-18M | $39M | $-36M | $-152M | $-31.0K | $-101.0K | $-12M | |
| Stock Issued | · | · | · | · | · | · | · | $0 | $0 | $0 | $0 | $0 | $-2M | $163M | $0 | $0 | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $0 | · | · | · | $163M | · | · | |
| Financing Cash Flow | $463M | $10M | $623.0K | $-368.0K | $218M | $234.0K | $40M | $1M | $2M | $90M | $90.0K | $-425.0K | $-3M | $237M | $-2M | $164.0K | |
| Taxes Paid | · | · | $0 | · | · | · | $-23.0K | · | · | · | · | · | · | · | · | · | |
| Free Cash Flow | · | $-19M | · | · | · | $-24M | · | · | · | $-23M | · | · | · | $-21M | · | · |
Rentabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -4.6% | -6.2% | · | -5.1% | -6.1% | -8.8% | · | -8.0% | -6.5% | -7.0% | · | -12.5% | -9.5% | -7.7% | · | -5.5% | |
| ROE | -4.7% | -6.4% | · | -5.3% | -6.4% | -9.4% | · | -8.4% | -6.8% | -7.5% | · | -13.0% | -9.8% | -8.1% | · | -5.9% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 64.1 | 40.3 | · | 32.9 | 32.6 | 21.1 | · | 17.4 | 14.4 | 13.5 | · | 22.2 | 31.0 | 27.2 | · | 32.5 | |
| Quick Ratio | 63.2 | 39.4 | · | 32.6 | 32.2 | 20.7 | · | 17.1 | 14.1 | 12.8 | · | 21.8 | 30.4 | 26.7 | · | 27.2 |
Valorisation (TTM) 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-102M | $-98M | · | $-97M | $-97M | $-94M | · | $-87M | $-80M | $-75M | · | $-63M | $-51M | $-43M | · | $-42M | |
| Market Cap | $3.72B | $2.39B | · | $1.21B | $1.19B | $965M | · | $1.21B | $1.10B | $823M | · | $563M | $840M | $900M | · | $240M | |
| P/E | -30.2 | -22.3 | · | -11.0 | -10.3 | -9.8 | · | -13.2 | -12.5 | -7.8 | · | -2.7 | -2.8 | -2.2 | · | -0.9 | |
| P/B | 4.2 | 5.3 | · | 2.5 | 2.4 | 3.3 | · | 4.2 | 3.6 | 2.6 | · | 2.2 | 3.0 | 3.1 | · | 4.2 | |
| P / Tangible Book | 4.2 | 5.3 | · | 2.5 | 2.4 | 3.3 | · | 4.2 | 3.6 | 2.6 | · | 2.2 | 3.0 | 3.1 | · | 4.2 | |
| P / Cash Flow | · | -123.7 | · | · | · | -40.0 | · | · | · | -35.2 | · | · | · | -43.2 | · | · | |
| P / FCF | · | -123.7 | · | · | · | -40.0 | · | · | · | -35.2 | · | · | · | -43.1 | · | · | |
| Earnings Yield | -3.3% | -4.5% | · | -9.1% | -9.7% | -10.2% | · | -7.6% | -8.0% | -12.8% | · | -36.5% | -36.0% | -45.4% | · | -108.3% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Résultat net | $-104M | $-89M | $-72M | $-38M | $-51M |
| BPA dilué | $-1.83 | $-1.89 | $-2.01 | $-12.05 | $-2.37 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 28.7 | 20.0 | 10.3 | 49.0 | 12.9 |
| Ratio de liquidité réduite | 27.9 | 19.7 | 9.8 | 48.2 | 6.7 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-70M | $-73M | $-61M | $-36M | $-47M |
Dernières actualités Actualités récentes mentionnant cette entreprise
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Détenteurs institutionnels (13F) 221 déclarants · $3.4B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 62 (-10 vs T. préc.) | 15 (0 vs T. préc.) | 77 (+19 vs T. préc.) | 51 (+18 vs T. préc.) | +12.8M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $449 607 902 | 8 859 269 | 13,25% | Actions |
| ORBIMED ADVISORS LLC | $343 914 074 | 6 776 632 | 10,13% | Actions |
| Polar Capital Holdings Plc | $326 354 777 | 6 430 636 | 9,62% | Actions |
| Vestal Point Capital, LP | $203 000 000 | 4 000 000 | 5,98% | Actions |
| Commodore Capital LP | $166 206 250 | 3 275 000 | 4,90% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $130 376 852 | 2 569 002 | 3,84% | Actions |
| CITADEL ADVISORS LLC | $101 874 840 | 2 007 386 | 3,00% | Actions |
| Fairmount Funds Management LLC | $94 173 933 | 1 855 644 | 2,78% | Actions |
| Siren, L.L.C. | $90 051 358 | 1 774 411 | 2,65% | Actions |
| Bellevue Group AG | $75 617 500 | 1 490 000 | 2,23% | Actions |
| First Light Asset Management, LLC | $69 058 063 | 1 360 750 | 2,04% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $62 098 160 | 1 223 306 | 1,83% | Actions |
| STATE STREET CORP | $61 591 012 | 1 213 616 | 1,82% | Actions |
| Pictet Asset Management Holding SA | $58 960 538 | 1 161 784 | 1,74% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $54 978 135 | 1 083 313 | 1,62% | Actions |
| NOVO HOLDINGS A/S | $50 750 000 | 1 000 000 | 1,50% | Actions |
| First Turn Management, LLC | $48 433 770 | 954 360 | 1,43% | Actions |
| BAKER BROS. ADVISORS LP | $45 938 443 | 905 191 | 1,35% | Actions |
| Candriam S.C.A. | $45 918 733 | 905 674 | 1,35% | Actions |
| Tri Locum Partners LP | $43 985 837 | 866 716 | 1,30% | Actions |
| ALLIANCEBERNSTEIN L.P. | $35 129 511 | 896 161 | 1,04% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $31 686 828 | 624 371 | 0,93% | Actions |
| Balyasny Asset Management L.P. | $30 814 842 | 607 189 | 0,91% | Actions |
| AMERICAN CENTURY COMPANIES INC | $28 732 976 | 566 165 | 0,85% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $28 560 222 | 562 763 | 0,84% | Actions |
| Avidity Partners Management LP | $27 912 500 | 550 000 | 0,82% | Actions |
| MARSHALL WACE, LLP | $26 713 227 | 526 369 | 0,79% | Actions |
| Venrock Adviser, LLC | $26 711 298 | 526 331 | 0,79% | Actions |
| Affinity Asset Advisors, LLC | $25 375 000 | 500 000 | 0,75% | Actions |
| SILVERARC CAPITAL MANAGEMENT, LLC | $24 836 137 | 489 382 | 0,73% | Actions |
| Logos Global Management LP | $23 598 750 | 465 000 | 0,70% | Actions |
| Rock Springs Capital Management LP | $23 579 719 | 464 625 | 0,69% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $21 540 330 | 424 440 | 0,63% | Actions |
| MILLENNIUM MANAGEMENT LLC | $20 876 622 | 411 362 | 0,62% | Actions |
| Nicholas Investment Partners, LP | $19 870 097 | 391 529 | 0,59% | Actions |
| ADAR1 Capital Management, LLC | $19 676 689 | 387 718 | 0,58% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $19 462 118 | 383 490 | 0,57% | Actions |
| SAMLYN CAPITAL, LLC | $17 678 966 | 348 354 | 0,52% | Actions |
| Woodline Partners LP | $17 617 457 | 347 142 | 0,52% | Actions |
| STEMPOINT CAPITAL LP | $17 605 886 | 346 914 | 0,52% | Actions |
| Spruce Street Capital LP | $16 697 055 | 329 006 | 0,49% | Actions |
| Longaeva Partners L.P. | $15 862 420 | 312 560 | 0,47% | Actions |
| JENNISON ASSOCIATES LLC | $15 692 866 | 309 219 | 0,46% | Actions |
| Assenagon Asset Management S.A. | $15 558 631 | 306 574 | 0,46% | Actions |
| D. E. Shaw & Co., Inc. | $15 514 427 | 305 703 | 0,46% | Actions |
| Seven Fleet Capital Management LP | $14 673 652 | 289 136 | 0,43% | Actions |
| GOLDMAN SACHS GROUP INC | $14 142 655 | 278 673 | 0,42% | Actions |
| AMERIPRISE FINANCIAL INC | $12 518 808 | 246 676 | 0,37% | Actions |
| Deep Track Capital, LP | $11 418 750 | 225 000 | 0,34% | Actions |
| Blackstone Inc. | $10 949 008 | 215 744 | 0,32% | Actions |
| Patient Square Capital LP | $10 784 375 | 212 500 | 0,32% | Actions |
| Soleus Capital Management, L.P. | $8 408 108 | 165 677 | 0,25% | Actions |
| Squadron Capital Management LLC | $8 120 000 | 160 000 | 0,24% | Actions |
| Connor, Clark & Lunn Investment Management Ltd. | $8 044 992 | 158 522 | 0,24% | Actions |
| Integral Health Asset Management, LLC | $7 612 500 | 150 000 | 0,22% | Actions |
| Cormorant Asset Management, LP | $7 612 500 | 150 000 | 0,22% | Actions |
| NEUBERGER BERMAN GROUP LLC | $7 131 187 | 140 516 | 0,21% | Actions |
| HighVista Strategies LLC | $6 996 700 | 137 866 | 0,21% | Actions |
| Eversept Partners, LP | $6 934 023 | 136 631 | 0,20% | Actions |
| Ikarian Capital, LLC | $6 421 957 | 126 541 | 0,19% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $5 722 824 | 112 765 | 0,17% | Actions |
| J. Goldman & Co LP | $5 690 547 | 112 129 | 0,17% | Actions |
| TD Asset Management Inc | $5 569 204 | 109 738 | 0,16% | Actions |
| Cinctive Capital Management LP | $5 465 166 | 107 688 | 0,16% | Actions |
| Exome Asset Management LLC | $5 085 302 | 100 203 | 0,15% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4 892 300 | 96 400 | 0,14% | Option d'achat |
| Swiss National Bank | $4 799 580 | 94 573 | 0,14% | Actions |
| VANGUARD GROUP INC | $4 679 767 | 303 881 | 0,14% | Actions |
| BANK OF AMERICA CORP /DE/ | $3 977 531 | 78 375 | 0,12% | Actions |
| DV EQUITIES, LLC | $3 869 688 | 76 250 | 0,11% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $3 819 699 | 75 265 | 0,11% | Actions |
| Artia Global Partners LP | $3 659 075 | 72 100 | 0,11% | Actions |
| ALGERT GLOBAL LLC | $3 658 568 | 72 090 | 0,11% | Actions |
| CITADEL ADVISORS LLC | $3 654 000 | 72 000 | 0,11% | Option de vente |
| Informed Momentum Co LLC | $3 574 424 | 70 432 | 0,11% | Actions |
| SEVEN GRAND MANAGERS, LLC | $3 552 500 | 70 000 | 0,10% | Actions |
| GREAT POINT PARTNERS LLC | $3 552 500 | 70 000 | 0,10% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $3 407 913 | 67 151 | 0,10% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $3 307 581 | 65 174 | 0,10% | Actions |
| BlackRock, Inc. | $3 106 306 | 61 208 | 0,09% | Actions |
| RHUMBLINE ADVISERS | $2 904 972 | 57 241 | 0,09% | Actions |
| Schonfeld Strategic Advisors LLC | $2 836 112 | 55 884 | 0,08% | Actions |
| Atom Investors LP | $2 543 692 | 50 122 | 0,07% | Actions |
| Caption Management, LLC | $2 537 500 | 50 000 | 0,07% | Option d'achat |
| Jones Hill Capital LP | $2 529 888 | 49 850 | 0,07% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $2 318 514 | 45 685 | 0,07% | Actions |
| TUDOR INVESTMENT CORP ET AL | $2 035 989 | 40 118 | 0,06% | Actions |
| WELLS FARGO & COMPANY/MN | $1 983 259 | 39 079 | 0,06% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $1 980 823 | 39 031 | 0,06% | Actions |
| JANE STREET GROUP, LLC | $1 908 200 | 37 600 | 0,06% | Option d'achat |
| Trexquant Investment LP | $1 902 668 | 37 491 | 0,06% | Actions |
| Bank of New York Mellon Corp | $1 766 658 | 34 811 | 0,05% | Actions |
| TimesSquare Capital Management, LLC | $1 764 000 | 45 000 | 0,05% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $1 696 674 | 33 432 | 0,05% | Actions |
| Ishara Investments LP | $1 664 600 | 32 800 | 0,05% | Actions |
| Brevan Howard Capital Management LP | $1 660 439 | 32 718 | 0,05% | Actions |
| Engineers Gate Manager LP | $1 479 464 | 29 152 | 0,04% | Actions |
| CITIGROUP INC | $1 433 180 | 28 240 | 0,04% | Actions |
| Vanguard Global Advisers, LLC | $1 361 775 | 26 833 | 0,04% | Actions |
| JANE STREET GROUP, LLC | $1 344 875 | 26 500 | 0,04% | Option de vente |
Initiés de la société 28 initiés · 7 dirigeants · 18 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Samuel Kintz | President and CEO | 25 janvier 2024 M | 0 | 0 | 0 | $0 |
| Benjamin Hohl | CHIEF FINANCIAL OFFICER | 17 juillet 2026 M | 46 054 | 0 | 8 | $-580 338 |
| Michael Gray | CFO & COO | 22 février 2023 S | 27 610 | 0 | 0 | $0 |
| Anish Patel | Chief Operating Officer | 22 janvier 2024 S | 17 222 | 0 | 0 | $0 |
| Helen Louise Collins | CHIEF MEDICAL OFFICER | 17 juillet 2026 M | 25 000 | 0 | 8 | $-482 386 |
| Joseph P Lyssikatos | Chief Scientific Officer | 29 décembre 2023 M | 0 | 0 | 0 | $0 |
| Kenneth Attie | SVP, CMO | 28 janvier 2022 A | 34 100 | 0 | 0 | $0 |
| Lori Anne Kunkel | Administrateur | 6 juillet 2026 S | 41 884 | 0 | 3 | $-771 524 |
| Rishi Gupta | Administrateur | 16 mai 2024 S | 7 663 349 | 0 | 0 | $0 |
| Richard A. Heyman | Administrateur | 22 décembre 2023 S | 29 216 | 0 | 0 | $0 |
| Andrew John Phillips | Administrateur | 23 février 2023 A | — | 0 | 0 | $0 |
| Rahul D. Ballal | Administrateur | 23 février 2023 A | 87 835 | 0 | 0 | $0 |
| Jake Bauer | Administrateur | 23 février 2023 A | 87 372 | 0 | 0 | $0 |
| Andrew J. Schwab | Administrateur | 23 février 2023 A | 960 383 | 0 | 0 | $0 |
| Laura A Williams | Administrateur | 2 juin 2022 A | — | 0 | 0 | $0 |
| Mark Chin | Administrateur | 2 juin 2022 A | 2 344 072 | 0 | 0 | $0 |
| Edward R. Conner | Administrateur | 2 juin 2022 A | — | 0 | 0 | $0 |
| Barbara Dalton | Administrateur | 2 juin 2022 A | 1 557 722 | 0 | 0 | $0 |
| David P Bonita | Administrateur | 2 juin 2022 A | 4 199 068 | 0 | 0 | $0 |
| David M Mott | Administrateur | 2 juin 2022 A | 229 224 | 0 | 0 | $0 |
| Carl Goldfischer | Administrateur | 2 juin 2022 A | — | 0 | 0 | $0 |
| James G Mcarthur | Administrateur | 16 mars 2020 A | — | 0 | 0 | $0 |
| Mette Kirstine Agger | Administrateur | 16 mars 2020 A | 1 432 722 | 0 | 0 | $0 |
| Alexandria Venture Investments, LLC | Détenteur de 10% | 16 mars 2020 C | 293 013 | 0 | 0 | $0 |
| Lundbeckfond Invest A/S | Détenteur de 10% | 16 mars 2020 C | 1 432 722 | 0 | 0 | $0 |
| H LUNDBECK A S | Détenteur de 10% | 16 mars 2020 C | 522 499 | 0 | 0 | $0 |
| Mika K Derynck | — | 4 août 2026 M | 0 | 0 | 1 | $-9 561 047 |
| Sara M. Nayeem | — | 29 juin 2021 A | — | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 7 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP VII LLC, ORBIMED GENESIS GP LLC, ORBIMED CAPITAL LLC ×7 dépôts | 24 juin 2026 | 9,50% | Amendement | — | SEC |
| 5AM Ventures VI, L.P., 5AM Partners VI, LLC, 5AM Opportunities I, L.P., 5AM Opportunities I (GP), LLC, Kush Parmar, Andrew J. Schwab ×5 dépôts | 29 juillet 2024 | — | Dépôt initial | — | SEC |
| 5AM Partners VI, LLC, 5AM Opportunities I, L.P., 5AM Opportunities I (GP), LLC, Kush Parmar, Andrew J. Schwab | 6 mars 2023 | — | Dépôt initial | Investissement passif | SEC |
| 24 mai 2022 | — | Dépôt initial | — | SEC | |
| New Enterprise Associates 14, L.P., NEA Partners 14, L.P., NEA 14 GP, LTD, Forest Baskett, Anthony A. Florence, Jr., Patrick J. Kerins, Scott D. Sandell, Peter W. Sonsini ×3 dépôts | 25 avril 2022 | — | Dépôt initial | Investissement passif | SEC |
| Arix Bioscience Plc, Arix Bioscience Holdings Limited, Mark Chin ×3 dépôts | 20 juillet 2021 | — | Dépôt initial | — | SEC |
| Arix Bioscience Plc (2), Arix Bioscience Holdings Limited (2), Mark Chin (1) (2) | 24 mars 2020 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 48 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 1,81% | 16 370 NS | 30 avril 2026 | N-PORT |
| PTH · Invesco Exchange-Traded Fund Trust | 1,80% | 73 604 SH | 8 août 2026 | Quotidien |
| PILL · Direxion Shares ETF Trust | 1,80% | 5 620 NS | 30 avril 2026 | N-PORT |
| CANC · Tema ETF Trust | 1,31% | 58 197 NS | 31 mai 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 1,03% | 10 703 NS | 31 mai 2026 | N-PORT |
| IHE · iShares Trust | 0,72% | 194 624 SH | 8 août 2026 | Quotidien |
| DWAS · Invesco Exchange-Traded Fund Trust … | 0,51% | 38 057 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,26% | 407 872 SH | 8 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,25% | 3 315 SH | 8 août 2026 | Quotidien |
| ESSC · Strategy Shares | 0,23% | 1 424 NS | 30 avril 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,16% | 51 358 NS | 30 avril 2026 | N-PORT |
| IWO · iShares Trust | 0,16% | 388 661 SH | 8 août 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,13% | 45 928 SH | 8 août 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | 0,12% | 47 349 SH | 8 août 2026 | Quotidien |
| BIB · ProShares Trust | 0,12% | 2 196 NS | 31 mai 2026 | N-PORT |
| NUSC · Nushares ETF Trust | 0,11% | 34 350 NS | 30 avril 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,09% | 61 669 NS | 31 mai 2026 | N-PORT |
| IWM · iShares Trust | 0,08% | 1 094 617 SH | 8 août 2026 | Quotidien |
| ISCG · iShares Trust | 0,07% | 12 024 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,07% | 246 533 SH | 8 août 2026 | Quotidien |
| ESML · iShares Trust | 0,07% | 33 580 SH | 8 août 2026 | Quotidien |
| ISCB · iShares Trust | 0,05% | 2 494 SH | 8 août 2026 | Quotidien |
| DFAS · Dimensional ETF Trust | 0,05% | 175 955 NS | 30 avril 2026 | N-PORT |
| VHT · VANGUARD WORLD FUND | 0,04% | 141 971 SH | 8 août 2026 | Quotidien |
| ITWO · ProShares Trust | 0,04% | 1 852 NS | 31 mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,04% | 214 005 NS | 31 mai 2026 | N-PORT |
| ISCV · iShares Trust | 0,03% | 3 976 SH | 8 août 2026 | Quotidien |
| VXF · VANGUARD INDEX FUNDS | 0,03% | 624 513 SH | 8 août 2026 | Quotidien |
| WSML · iShares Trust | 0,03% | 2 892 SH | 8 août 2026 | Quotidien |
| UWM · ProShares Trust | 0,02% | 1 449 NS | 31 mai 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,02% | 14 804 NS | 30 avril 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,02% | 8 632 SH | 8 août 2026 | Quotidien |
| URTY · ProShares Trust | 0,02% | 1 465 NS | 31 mai 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 1 649 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 22 815 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 37 NS | 31 mai 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 4 666 NS | 30 avril 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,01% | 569 NS | 30 avril 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 66 943 SH | 8 août 2026 | Quotidien |
| IWV · iShares Trust | 0,00% | 12 036 SH | 8 août 2026 | Quotidien |
| DFUS · Dimensional ETF Trust | 0,00% | 14 379 NS | 30 avril 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 7 755 NS | 30 avril 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 30 821 NS | 31 mai 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 28 939 NS | 30 avril 2026 | N-PORT |
| TILT · FlexShares Trust | 0,00% | 154 NS | 30 avril 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 691 NS | 31 mai 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 883 832 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 3 533 SH | 8 août 2026 | Quotidien |