ANNX Annexon, Inc. - common stock
$5,54
Prix · Aoû 19, 2026
Données fondamentales au Aoû 12, 2026
Fourchette 52 semaines
$2–$7
68% of range
Note des analystes
BUY
17 analysts
Objectif de cours
$15
+166% upside
P/E (TTM)
-4.1
ROE
-100.7%
Marge nette
—
ANNX Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
Prix
$5.54
Capitalisation Boursière
$827M
P/E (TTM)
-4.1
BPA (TTM)
$-1.34
Revenus (TTM)
—
Rendement div.
—
ROE
-100.7%
Dette/Capitaux propres
—
Fourchette 52 semaines
$2 – $7
ANNX Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Configure
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Revenus et bénéfice net
—
BPA
$-1.34
2021-12-31
→
2025-12-31
Flux de trésorerie libre
$-186M
2020-12-31
→
2025-12-31
Marges
—
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Métrique
Tendance sur 5 ans
ANNX
Médiane des pairs
P/E (TTM)
-4.1
—
P/B
3.9
3.4
Price / FCF (Cours / FCF)
-4.4
—
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Métrique
Tendance sur 5 ans
ANNX
Médiane des pairs
ROA
-65.9%
-31.3%
ROE
-100.7%
-38.1%
ROIC
-102.2%
—
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Métrique
Tendance sur 5 ans
ANNX
Médiane des pairs
Current Ratio (Ratio de liquidité)
5.7
10.9
Quick Ratio (Ratio de liquidité réduite)
3.8
—
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Métrique
Tendance sur 5 ans
ANNX
Médiane des pairs
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
Métrique
Tendance sur 5 ans
ANNX
Médiane des pairs
ANNX Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
ACHAT
17 analystes
- Achat fort 4 23,5%
- Achat 10 58,8%
- Conserver 2 11,8%
- Vente 1 5,9%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
7 analystes · 2026-08-17
Médiane
$12.00
Moyenne
$14.71
← En dessous de tous les objectifs
$5.54
Bas
$7.00
Haut
$27.00
Objectif médian
$12.00
+116,8%
Objectif moyen
$14.71
+165,8%
Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
Surprise Moyenne
-0.00%
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 31 mars 2026 | $-0.23 | $-0.29 | 0.06% |
| 31 décembre 2025 | $-0.28 | $-0.32 | 0.04% |
| 30 septembre 2025 | $-0.37 | $-0.35 | -0.02% |
| 30 juin 2025 | $-0.34 | $-0.37 | 0.03% |
| 31 mars 2025 | $-0.37 | $-0.30 | -0.07% |
| 31 décembre 2024 | $-0.33 | $-0.27 | -0.06% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| ANNX | $750M | -3.7 | — | — | -100.7% | — |
| SVRA | $1.23B | -11.4 | — | — | -73.4% | — |
| KURA | $913M | -3.3 | 25.2% | -413.0% | -116.2% | — |
| AVTX | $336M | -3.1 | -86.6% | -132642.4% | -83.4% | — |
| JANX | $833M | -7.5 | -5.5% | -1136.2% | -11.7% | — |
| SLDB | $445M | -2.8 | — | — | -79.5% | — |
| GERN | $845M | -10.2 | -60.2% | — | -34.4% | — |
| ARDX | $1.42B | -22.4 | 22.1% | -15.1% | -40.2% | — |
| CADL | $310M | -7.8 | — | — | -53.7% | — |
| DSGN | $567M | -7.7 | — | — | -32.8% | — |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 13
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $185M | $119M | $114M | $113M | $100M | $49M | $25M | |
| SG&A Expense | $32M | $35M | $30M | $33M | $31M | $14M | $8M | |
| Operating Expenses | $216M | $154M | $144M | $146M | $131M | $63M | $33M | |
| Operating Income | $-216M | $-154M | $-144M | $-146M | $-131M | $-63M | $-33M | |
| Other Non-op | · | · | · | · | · | $57.0K | $1M | |
| Pretax Income | $-207M | $-138M | $134M | $142M | $130M | $-63M | $-37M | |
| Income Tax | $0 | $0 | $0 | $0 | · | · | $4.0K | |
| Net Income | $-207M | $-138M | $-134M | $-142M | $-130M | $-63M | $-37M | |
| EPS (Basic) | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 | · | · | |
| EPS (Diluted) | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 | · | · | |
| Shares (Basic) | 155,105,832 | 137,404,145 | 75,673,081 | 54,673,572 | 38,316,273 | · | · | |
| Shares (Diluted) | 155,105,832 | 137,404,145 | 75,673,081 | 54,673,572 | 38,316,273 | · | · | |
| EBITDA | $-214M | $-152M | $-142M | $-143M | $-129M | $-63M | · |
Bilan 21
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $162M | $49M | $225M | $140M | $75M | $269M | $44M | |
| Prepaid Expense | $4M | $4M | $4M | $5M | $5M | $3M | $1M | |
| Other Current Assets | · | · | $63.0K | $203.0K | $463.0K | $3.0K | $79.0K | |
| Current Assets | $242M | $316M | $264M | $248M | $248M | $354M | $45M | |
| PP&E (Net) | $11M | $13M | $15M | $17M | $18M | $2M | $2M | |
| PP&E (Gross) | $20M | $20M | $20M | $20M | $19M | $4M | $3M | |
| Accum. Depreciation | $9M | $7M | $5M | $3M | $789.0K | $2M | $1M | |
| Other Non-current Assets | $9M | $3M | · | · | · | · | $2M | |
| Total Assets | $278M | $350M | $298M | $285M | $287M | $356M | $50M | |
| Accounts Payable | $15M | $10M | $5M | $7M | $11M | $4M | $2M | |
| Accrued Liabilities | · | · | $10M | $13M | $9M | $6M | $2M | |
| Current Liabilities | $43M | $31M | $18M | $22M | $22M | $11M | $5M | |
| Capital Leases | $23M | $26M | $29M | $32M | $33M | · | · | |
| Total Liabilities | $66M | $57M | $47M | $54M | $55M | $12M | $6M | |
| Common Stock | $149.0K | $109.0K | $78.0K | $48.0K | $39.0K | $38.0K | $4.0K | |
| Paid-in Capital | $1.13B | $1.00B | $823M | $670M | $528M | $510M | $2M | |
| Retained Earnings | $-917M | $-711M | $-572M | $-438M | $-296M | $-166M | $-103M | |
| AOCI | $-29.0K | $10.0K | $-52.0K | $-372.0K | $-180.0K | $-77.0K | $-80.0K | |
| Stockholders' Equity | $212M | $293M | $251M | $231M | $232M | $344M | $-100M | |
| Liabilities + Equity | $278M | $350M | $298M | $285M | $287M | $356M | $50M | |
| Shares Outstanding | 149,362,800 | 109,381,556 | 78,369,099 | 47,722,995 | 38,560,854 | 38,157,618 | 433,749 |
Flux de trésorerie 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $2M | $2M | $667.0K | $493.0K | |
| Stock-based Comp | $16M | $19M | $18M | $19M | $16M | $5M | $2M | |
| Other Non-cash | $2M | $-1M | $-7M | $5M | $6M | $5M | · | |
| Operating Cash Flow | $-186M | $-118M | $-121M | $-116M | $-106M | $-53M | $-28M | |
| CapEx | $137.0K | $15.0K | $193.0K | $7M | $2M | $464.0K | $267.0K | |
| Investing Cash Flow | $190M | $-219M | $71M | $58M | $-88M | $-83M | $-267.0K | |
| Stock Issued | $28M | $44M | $18M | · | · | · | · | |
| Net Stock Activity | $28M | $44M | · | · | · | · | · | |
| Financing Cash Flow | $109M | $161M | $136M | $123M | $2M | $361M | $28M | |
| Free Cash Flow | $-186M | $-118M | $-121M | $-123M | $-108M | $-54M | · |
Rentabilité 3
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -65.9% | -42.7% | -46.1% | -49.6% | -40.5% | -31.2% | · | |
| ROE | -100.7% | -44.2% | -65.9% | -57.7% | -52.5% | -17.9% | · | |
| ROIC | -102.2% | -52.6% | -57.4% | · | · | · | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.7 | 10.4 | 14.7 | 11.1 | 11.4 | 33.3 | · | |
| Quick Ratio | 3.8 | 1.6 | 12.6 | 6.3 | 3.4 | 25.3 | · |
Valorisation (TTM) 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-207M | $-138M | $-134M | $-142M | $-130M | $-63M | · | |
| Market Cap | $750M | $561M | $356M | $247M | $443M | $955M | · | |
| P/E | -3.7 | -5.1 | -2.6 | -2.0 | -3.4 | · | · | |
| P/B | 3.5 | 1.9 | 1.4 | 1.1 | 1.9 | 2.8 | · | |
| P / Tangible Book | 3.5 | 1.9 | 1.4 | 1.1 | 1.9 | 2.8 | · | |
| P / Cash Flow | -4.0 | -4.8 | -2.9 | -2.1 | -4.2 | -18.0 | · | |
| P / FCF | -4.0 | -4.8 | -2.9 | -2.0 | -4.1 | -17.8 | · | |
| Earnings Yield | -26.7% | -19.7% | -39.0% | -50.3% | -29.6% | · | · |
Compte de résultat 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $47M | $36M | $43M | $50M | $44M | $48M | $43M | $30M | $25M | $21M | $23M | $28M | $30M | $32M | $29M | $28M | |
| SG&A Expense | $11M | $10M | $8M | $7M | $8M | $9M | $9M | $9M | $9M | $8M | $7M | $7M | $7M | $9M | $8M | $8M | |
| Operating Expenses | $57M | $46M | $50M | $57M | $52M | $57M | $52M | $39M | $34M | $29M | $30M | $35M | $38M | $41M | $37M | $36M | |
| Operating Income | $-57M | $-46M | $-50M | $-57M | $-52M | $-57M | $-52M | $-39M | $-34M | $-29M | $-30M | $-35M | $-38M | $-41M | $-37M | $-36M | |
| Net Income | $-55M | $-44M | $-48M | $-55M | $-49M | $-54M | $-49M | $-35M | $-30M | $-25M | $-28M | $-32M | $-35M | $-39M | $-34M | $-35M | |
| EPS (Basic) | $-0.28 | $-0.23 | $-0.26 | $-0.37 | $-0.34 | $-0.37 | $-0.32 | $-0.25 | $-0.23 | $-0.21 | $-0.35 | $-0.43 | $-0.47 | $-0.52 | $-0.21 | $-0.51 | |
| EPS (Diluted) | $-0.28 | $-0.23 | $-0.26 | $-0.37 | $-0.34 | $-0.37 | $-0.32 | $-0.25 | $-0.23 | $-0.21 | $-0.35 | $-0.43 | $-0.47 | $-0.52 | $-0.21 | $-0.51 | |
| Shares (Basic) | 201,003,269 | 194,200,100 | -290,447,481 | 149,123,701 | 148,320,803 | 148,108,809 | -255,335,036 | 139,933,019 | 130,132,960 | 122,673,202 | -148,755,059 | 75,342,495 | 75,230,003 | 73,855,642 | -91,127,071 | 68,652,859 | |
| Shares (Diluted) | 201,003,269 | 194,200,100 | -290,447,481 | 149,123,701 | 148,320,803 | 148,108,809 | -255,335,036 | 139,933,019 | 130,132,960 | 122,673,202 | -148,755,059 | 75,342,495 | 75,230,003 | 73,855,642 | -91,127,071 | 68,652,859 | |
| EBITDA | $-57M | $-46M | · | $-57M | $-52M | $-57M | · | $-39M | $-34M | $-28M | · | $-35M | $-38M | $-41M | · | $-36M |
Bilan 21
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $199M | $175M | $162M | $139M | $132M | $97M | $49M | $80M | $157M | $152M | $225M | $133M | $114M | $144M | $140M | $211M | |
| Prepaid Expense | $4M | $3M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $6M | $4M | $4M | $5M | $4M | $5M | $5M | |
| Other Current Assets | · | · | · | · | · | · | · | · | · | $23.0K | · | $13.0K | $167.0K | $165.0K | $203.0K | $57.0K | |
| Current Assets | $213M | $228M | $242M | $193M | $231M | $268M | $316M | $344M | $374M | $271M | $264M | $169M | $198M | $233M | $248M | $275M | |
| PP&E (Net) | $10M | $10M | $11M | $11M | $12M | $12M | $13M | $13M | $14M | $14M | $15M | $15M | $16M | $16M | $17M | $17M | |
| PP&E (Gross) | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $19M | |
| Accum. Depreciation | $10M | $10M | $9M | $9M | $8M | $8M | $7M | $7M | $6M | $6M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Other Non-current Assets | $8M | $9M | $9M | $9M | $5M | $5M | $3M | $3M | · | $361.0K | · | · | · | $12.0K | · | $204.0K | |
| Total Assets | $246M | $263M | $278M | $229M | $265M | $303M | $350M | $379M | $406M | $304M | $298M | $204M | $233M | $269M | $285M | $313M | |
| Accounts Payable | $16M | $18M | $15M | $18M | $12M | $10M | $10M | $7M | $4M | $4M | $5M | $5M | $7M | $10M | $7M | $7M | |
| Accrued Liabilities | · | · | · | · | · | · | · | · | $11M | $7M | · | $10M | $9M | $11M | $13M | $11M | |
| Current Liabilities | $38M | $36M | $43M | $44M | $41M | $34M | $31M | $20M | $17M | $13M | $18M | $17M | $18M | $23M | $22M | $20M | |
| Capital Leases | $22M | $22M | $23M | $24M | $25M | $26M | $26M | $27M | $28M | $29M | $29M | $30M | $30M | $31M | $32M | $32M | |
| Total Liabilities | $60M | $58M | $66M | $68M | $66M | $59M | $57M | $47M | $45M | $42M | $47M | $47M | $48M | $54M | $54M | $52M | |
| Common Stock | $175.0K | $162.0K | $149.0K | $115.0K | $110.0K | $109.0K | $109.0K | $106.0K | $106.0K | $90.0K | $78.0K | $53.0K | $53.0K | $53.0K | $48.0K | $48.0K | |
| Paid-in Capital | $1.20B | $1.17B | $1.13B | $1.03B | $1.01B | $1.01B | $1.00B | $993M | $988M | $860M | $823M | $702M | $697M | $692M | $670M | $665M | |
| Retained Earnings | $-1.02B | $-962M | $-917M | $-869M | $-814M | $-765M | $-711M | $-662M | $-627M | $-598M | $-572M | $-545M | $-512M | $-477M | $-438M | $-404M | |
| AOCI | $-82.0K | $-81.0K | $-29.0K | $-76.0K | $-93.0K | $-91.0K | $10.0K | $77.0K | $-89.0K | $-102.0K | $-52.0K | $-123.0K | $-171.0K | $-217.0K | $-372.0K | $-406.0K | |
| Stockholders' Equity | $186M | $205M | $212M | $161M | $199M | $244M | $293M | $332M | $361M | $262M | $251M | $157M | $185M | $215M | $231M | $261M | |
| Liabilities + Equity | $246M | $263M | $278M | $229M | $265M | $303M | $350M | $379M | $406M | $304M | $298M | $204M | $233M | $269M | $285M | $313M | |
| Shares Outstanding | · | · | 149,362,800 | · | · | · | 109,381,556 | · | · | · | 78,369,099 | · | · | · | 47,722,995 | · |
Flux de trésorerie 10
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $540.0K | $539.0K | $543.0K | $546.0K | $540.0K | $537.0K | $537.0K | $538.0K | $537.0K | $538.0K | $538.0K | $538.0K | $536.0K | $536.0K | $530.0K | $518.0K | |
| Stock-based Comp | $5M | $4M | $3M | $4M | $4M | $5M | $5M | $5M | $5M | $5M | $4M | $5M | $5M | $5M | $5M | $5M | |
| Other Non-cash | · | $-7M | · | · | · | $-1M | · | · | · | $-8M | · | · | · | $540.0K | · | · | |
| Operating Cash Flow | $-48M | $-47M | $-46M | $-52M | $-38M | $-50M | $-36M | $-32M | $-22M | $-28M | $-23M | $-28M | $-36M | $-33M | $-27M | $-31M | |
| CapEx | $137.0K | $0 | $0 | $48.0K | $15.0K | $74.0K | $6.0K | · | · | · | $7.0K | $19.0K | $30.0K | $137.0K | $282.0K | $169.0K | |
| Investing Cash Flow | $40M | $27M | $-27M | $46M | $73M | $98M | $1M | $-46M | $-97M | $-77M | $-2M | $48M | $6M | $20M | $-44M | $14M | |
| Stock Issued | $32M | $34M | $14M | $14M | $0 | $0 | $5M | $0 | $7M | $33M | $0 | $450.0K | $450.0K | $18M | · | · | |
| Net Stock Activity | · | $34M | · | · | · | · | · | · | · | $33M | · | · | · | $18M | · | · | |
| Financing Cash Flow | $32M | $33M | $95M | $14M | $153.0K | $59.0K | $5M | $175.0K | $124M | $32M | $118M | $0 | $345.0K | $18M | $108.0K | $123M | |
| Free Cash Flow | · | $-47M | · | · | · | $-50M | · | · | · | · | · | · | · | $-33M | · | · |
Rentabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -21.7% | -15.6% | · | -18.1% | -14.7% | -17.9% | · | -11.9% | -9.3% | -9.1% | · | -13.8% | -15.5% | · | · | -11.3% | |
| ROE | -28.7% | -19.7% | · | -22.3% | -17.5% | -21.5% | · | -14.3% | -10.8% | -10.9% | · | -17.5% | -20.0% | · | · | -13.4% |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.5 | 6.4 | · | 4.4 | 5.7 | 8.0 | · | 17.2 | 21.8 | 20.6 | · | 9.9 | 11.0 | · | · | 13.6 | |
| Quick Ratio | 5.2 | 4.9 | · | 3.2 | 3.3 | 2.9 | · | 4.0 | 9.2 | 11.6 | · | 7.8 | 6.4 | · | · | 10.4 |
Valorisation (TTM) 3
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-204M | $-203M | · | $-193M | $-168M | $-144M | · | $-122M | $-122M | $-132M | · | $-141M | $-146M | $-146M | · | $-143M | |
| P/E | -4.7 | -4.2 | · | -2.3 | -2.0 | -1.8 | · | -5.3 | -3.7 | -4.4 | · | -1.2 | -1.4 | -1.3 | · | -1.9 | |
| Earnings Yield | -21.4% | -23.6% | · | -43.6% | -49.6% | -54.9% | · | -18.9% | -27.4% | -22.7% | · | -81.8% | -69.9% | -75.6% | · | -53.7% |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Résultat net | $-207M | $-138M | $-134M | $-142M | $-130M |
| BPA dilué | $-1.34 | $-1.01 | $-1.77 | $-2.60 | $-3.40 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio de liquidité | 5.7 | 10.4 | 14.7 | 11.1 | 11.4 |
| Ratio de liquidité réduite | 3.8 | 1.6 | 12.6 | 6.3 | 3.4 |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flux de trésorerie libre | $-186M | $-118M | $-121M | $-123M | $-108M |
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Détenteurs institutionnels (13F) 232 déclarants · $903.9M total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
Activité institutionnelle — Q2 2026 vs trimestre précédent
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 38 (-24 vs T. préc.) | 25 (+10 vs T. préc.) | 85 (+4 vs T. préc.) | 69 (+15 vs T. préc.) | +33.9M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| FMR LLC | $103 712 963 | 18 163 391 | 11,47% | Actions |
| Redmile Group, LLC | $67 776 998 | 11 869 877 | 7,50% | Actions |
| STATE STREET CORP | $56 096 873 | 9 824 321 | 6,21% | Actions |
| BVF INC/IL | $49 666 568 | 8 698 173 | 5,49% | Actions |
| Woodline Partners LP | $39 542 133 | 6 925 067 | 4,37% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $39 233 496 | 6 871 015 | 4,34% | Actions |
| SATTER MANAGEMENT CO., L.P. | $37 992 903 | 7 406 024 | 4,20% | Actions |
| VANGUARD GROUP INC | $34 414 053 | 6 855 389 | 3,81% | Actions |
| MAK CAPITAL ONE LLC | $33 473 048 | 5 862 180 | 3,70% | Actions |
| Siren, L.L.C. | $25 458 869 | 4 458 646 | 2,82% | Actions |
| Bain Capital Life Sciences Investors, LLC | $25 339 444 | 4 437 731 | 2,80% | Actions |
| Bellevue Group AG | $23 411 091 | 4 100 016 | 2,59% | Actions |
| MPM BIOIMPACT LLC | $20 238 261 | 3 544 354 | 2,24% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $19 985 000 | 3 500 000 | 2,21% | Actions |
| GREAT POINT PARTNERS LLC | $19 985 000 | 3 500 000 | 2,21% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $19 758 078 | 3 459 611 | 2,19% | Actions |
| AMERIPRISE FINANCIAL INC | $19 595 144 | 3 431 724 | 2,17% | Actions |
| GOLDMAN SACHS GROUP INC | $17 924 655 | 3 139 169 | 1,98% | Actions |
| Palo Alto Investors LP | $16 833 594 | 2 948 090 | 1,86% | Actions |
| Balyasny Asset Management L.P. | $16 164 873 | 2 830 976 | 1,79% | Actions |
| Qube Research & Technologies Ltd | $15 702 277 | 2 749 961 | 1,74% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12 829 228 | 2 246 800 | 1,42% | Actions |
| Opaleye Management Inc. | $9 789 515 | 1 714 451 | 1,08% | Actions |
| Logos Global Management LP | $8 565 000 | 1 500 000 | 0,95% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $8 139 776 | 1 425 530 | 0,90% | Actions |
| Point72 Asset Management, L.P. | $7 895 211 | 1 382 699 | 0,87% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $7 182 032 | 1 257 799 | 0,79% | Actions |
| Tetragon Partners GP Ltd | $7 094 418 | 1 242 455 | 0,78% | Actions |
| Candriam S.C.A. | $6 817 695 | 1 195 142 | 0,75% | Actions |
| MILLENNIUM MANAGEMENT LLC | $6 765 956 | 1 184 931 | 0,75% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $6 312 120 | 1 105 450 | 0,70% | Actions |
| PANAGORA ASSET MANAGEMENT INC | $5 526 857 | 967 926 | 0,61% | Actions |
| KENNEDY CAPITAL MANAGEMENT LLC | $5 129 830 | 898 394 | 0,57% | Actions |
| Ishara Investments LP | $4 682 200 | 820 000 | 0,52% | Actions |
| Ensign Peak Advisors, Inc | $4 570 946 | 800 516 | 0,51% | Actions |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $4 213 609 | 737 935 | 0,47% | Actions |
| Y-Intercept (Hong Kong) Ltd | $4 194 480 | 734 585 | 0,46% | Actions |
| Parkman Healthcare Partners LLC | $3 660 276 | 641 029 | 0,40% | Actions |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $3 334 143 | 583 913 | 0,37% | Actions |
| SIRIOS CAPITAL MANAGEMENT L P | $3 250 566 | 569 276 | 0,36% | Actions |
| Schonfeld Strategic Advisors LLC | $3 046 666 | 533 567 | 0,34% | Actions |
| TWO SIGMA INVESTMENTS, LP | $2 928 065 | 512 796 | 0,32% | Actions |
| Board of Trustees of The Leland Stanford Junior University | $2 755 360 | 482 550 | 0,30% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $2 620 890 | 459 000 | 0,29% | Actions |
| BANK OF AMERICA CORP /DE/ | $2 487 008 | 435 553 | 0,28% | Actions |
| Ikarian Capital, LLC | $2 456 693 | 430 244 | 0,27% | Actions |
| MOORE CAPITAL MANAGEMENT, LP | $2 428 646 | 425 332 | 0,27% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2 352 520 | 412 000 | 0,26% | Option d'achat |
| Trexquant Investment LP | $2 339 199 | 409 667 | 0,26% | Actions |
| Susquehanna Portfolio Strategies, LLC | $2 256 763 | 395 230 | 0,25% | Actions |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $2 253 166 | 394 600 | 0,25% | Actions |
| DIADEMA PARTNERS LP | $2 016 772 | 353 200 | 0,22% | Option d'achat |
| Engineers Gate Manager LP | $1 821 815 | 319 057 | 0,20% | Actions |
| DAFNA Capital Management LLC | $1 700 507 | 297 812 | 0,19% | Actions |
| Jump Financial, LLC | $1 700 438 | 297 800 | 0,19% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 635 201 | 286 375 | 0,18% | Actions |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $1 427 643 | 250 025 | 0,16% | Actions |
| UBS Group AG | $1 413 653 | 247 575 | 0,16% | Actions |
| Swiss National Bank | $1 396 666 | 244 600 | 0,15% | Actions |
| CITADEL ADVISORS LLC | $1 340 137 | 234 700 | 0,15% | Option d'achat |
| CITIGROUP INC | $1 296 318 | 227 026 | 0,14% | Actions |
| Cinctive Capital Management LP | $1 231 921 | 215 748 | 0,14% | Actions |
| MARSHALL WACE, LLP | $1 202 566 | 210 607 | 0,13% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 086 042 | 190 200 | 0,12% | Option de vente |
| RHUMBLINE ADVISERS | $1 082 480 | 189 578 | 0,12% | Actions |
| Bank of New York Mellon Corp | $1 002 413 | 175 554 | 0,11% | Actions |
| Squarepoint Ops LLC | $989 457 | 173 285 | 0,11% | Actions |
| Rafferty Asset Management, LLC | $989 423 | 173 279 | 0,11% | Actions |
| Point72 Europe (London) LLP | $923 726 | 302 861 | 0,10% | Actions |
| OSAIC HOLDINGS, INC. | $842 767 | 147 595 | 0,09% | Actions |
| ALLIANCEBERNSTEIN L.P. | $815 710 | 147 240 | 0,09% | Actions |
| WELLS FARGO & COMPANY/MN | $809 090 | 141 697 | 0,09% | Actions |
| BlackRock, Inc. | $782 276 | 137 001 | 0,09% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $738 234 | 129 288 | 0,08% | Actions |
| VICTORY CAPITAL MANAGEMENT INC | $727 100 | 127 338 | 0,08% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $685 937 | 120 129 | 0,08% | Actions |
| IEQ CAPITAL, LLC | $685 257 | 120 010 | 0,08% | Actions |
| J. Goldman & Co LP | $662 623 | 116 046 | 0,07% | Actions |
| XTX Topco Ltd | $640 359 | 112 147 | 0,07% | Actions |
| Vanguard Global Advisers, LLC | $582 803 | 102 067 | 0,06% | Actions |
| Quarry LP | $571 000 | 100 000 | 0,06% | Actions |
| Russell Investments Group, Ltd. | $566 711 | 99 249 | 0,06% | Actions |
| SCS Capital Management LLC | $565 290 | 99 000 | 0,06% | Actions |
| Nuveen, LLC | $564 508 | 98 863 | 0,06% | Actions |
| MetLife Investment Management, LLC | $519 639 | 91 005 | 0,06% | Actions |
| JANE STREET GROUP, LLC | $516 755 | 90 500 | 0,06% | Option d'achat |
| J. Safra Sarasin Holding AG | $516 681 | 90 487 | 0,06% | Actions |
| CITADEL ADVISORS LLC | $507 619 | 88 900 | 0,06% | Option de vente |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $505 438 | 88 518 | 0,06% | Actions |
| CAPTRUST FINANCIAL ADVISORS | $501 960 | 87 909 | 0,06% | Actions |
| PROFUND ADVISORS LLC | $499 676 | 87 509 | 0,06% | Actions |
| VANGUARD ASSET MANAGEMENT, Ltd | $453 865 | 79 486 | 0,05% | Actions |
| DNB Asset Management AS | $417 669 | 73 147 | 0,05% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $408 448 | 71 532 | 0,05% | Actions |
| Virtus Investment Advisers, LLC | $396 662 | 69 468 | 0,04% | Actions |
| Jain Global LLC | $369 545 | 64 719 | 0,04% | Actions |
| China Universal Asset Management Co., Ltd. | $354 454 | 62 076 | 0,04% | Actions |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $354 437 | 62 073 | 0,04% | Actions |
| DIVERSIFIED TRUST CO | $352 860 | 61 797 | 0,04% | Actions |
| Invesco Ltd. | $351 696 | 61 593 | 0,04% | Actions |
Initiés de la société 11 initiés · 3 dirigeants · 7 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Jennifer Lew | EVP & Chief Financial Officer | 11 juillet 2023 S | 47 460 | 0 | 0 | $0 |
| Ted Yednock | EVP & CHIEF INNOVATION OFFICER | 11 juin 2026 M | 184 807 | 0 | 0 | $0 |
| Michael Overdorf | EVP & Chief Business Officer | 11 juillet 2023 S | 45 802 | 0 | 0 | $0 |
| Bettina M. Cockroft | Administrateur | 11 juin 2026 A | — | 0 | 0 | $0 |
| William H. Carson | Administrateur | 11 juin 2026 A | — | 0 | 0 | $0 |
| Jung Choi | Administrateur | 11 juin 2026 A | — | 0 | 0 | $0 |
| William D. Waddill | Administrateur | 11 juin 2026 A | — | 0 | 0 | $0 |
| William A Jones JR | Administrateur | 11 juin 2026 A | — | 0 | 0 | $0 |
| Satter Muneer A | Administrateur | 11 juin 2026 A | 10 342 134 | 6 | 0 | $11 974 803 |
| Ricky Sun | Administrateur | 2 juin 2021 A | — | 0 | 0 | $0 |
| Mark S. Blumenkranz | — | 10 août 2026 A | — | 0 | 0 | $0 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 3 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| Satter Muneer A | 21 novembre 2025 | 7,20% | Amendement | — | SEC |
| Muneer A. Satter ×2 dépôts | 17 février 2023 | — | Dépôt initial | — | SEC |
| Clarus Lifesciences III, L.P., Clarus Ventures III GP, L.P., Blackstone Clarus III L.L.C., Blackstone Holdings II L.P., Blackstone Holdings I/II GP L.L.C., Blackstone Inc., Blackstone Group Management L.L.C., Stephen A. Schwarzman ×2 dépôts | 27 août 2021 | — | Dépôt initial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 38 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 0,87% | 55 535 NS | 30 avril 2026 | N-PORT |
| IBRN · iShares Trust | 0,81% | 11 173 SH | 8 août 2026 | Quotidien |
| LABU · Direxion Shares ETF Trust | 0,25% | 218 784 NS | 30 avril 2026 | N-PORT |
| IWC · iShares Trust | 0,20% | 527 497 SH | 8 août 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | 0,13% | 451 913 SH | 8 août 2026 | Quotidien |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,07% | 37 506 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,06% | 1 058 884 SH | 8 août 2026 | Quotidien |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,06% | 8 919 SH | 8 août 2026 | Quotidien |
| IWO · iShares Trust | 0,05% | 1 395 356 SH | 8 août 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,05% | 166 500 SH | 8 août 2026 | Quotidien |
| BIB · ProShares Trust | 0,04% | 5 349 NS | 31 mai 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,04% | 198 690 SH | 8 août 2026 | Quotidien |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,03% | 893 974 SH | 8 août 2026 | Quotidien |
| IWM · iShares Trust | 0,03% | 3 979 848 SH | 8 août 2026 | Quotidien |
| ISCV · iShares Trust | 0,02% | 31 162 SH | 8 août 2026 | Quotidien |
| RSSL · Global X Funds | 0,02% | 57 102 NS | 30 avril 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 6 206 NS | 31 mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,02% | 637 833 NS | 31 mai 2026 | N-PORT |
| ISCB · iShares Trust | 0,01% | 6 291 SH | 8 août 2026 | Quotidien |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 54 687 NS | 30 avril 2026 | N-PORT |
| UWM · ProShares Trust | 0,01% | 4 853 NS | 31 mai 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 1 754 465 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,01% | 366 971 SH | 8 août 2026 | Quotidien |
| URTY · ProShares Trust | 0,01% | 4 907 NS | 31 mai 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,01% | 179 974 NS | 30 avril 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 7 256 SH | 8 août 2026 | Quotidien |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 69 949 NS | 31 mai 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 123 NS | 31 mai 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 3 773 NS | 31 mai 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 180 473 NS | 30 avril 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,00% | 9 567 NS | 31 mai 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 54 273 SH | 8 août 2026 | Quotidien |
| ITOT · iShares Trust | 0,00% | 219 943 SH | 8 août 2026 | Quotidien |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 79 390 NS | 31 mai 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 15 085 NS | 30 avril 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 13 707 NS | 30 avril 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 4 970 636 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 13 754 SH | 8 août 2026 | Quotidien |