MLYS Mineralys Therapeutics, Inc. - Common Stock
MLYS Aperçu de l'action Prix, capitalisation boursière, P/E, EPS, ROE, dette/capitaux propres, fourchette sur 52 semaines
MLYS Graphique du cours de l'action OHLCV quotidien avec indicateurs techniques — panoramique, zoom et personnalisez votre vue
Performance sur 10 ans Tendances du chiffre d'affaires, du bénéfice net, des marges et du BPA
Valorisation Ratios P/E, P/S, P/B, EV/EBITDA — l'action est-elle chère ou bon marché ?
Rentabilité Marges brutes, d'exploitation et nettes ; ROE, ROA, ROIC
Santé financière Dette, liquidité, solvabilité — solidité du bilan
Croissance Croissance du chiffre d'affaires, du BPA et du bénéfice net : Année/Année, TCAC 3 ans, TCAC 5 ans
Efficacité du capital Rotation des actifs, rotation des stocks, rotation des créances
MLYS Consensus des analystes Opinions des analystes haussières et baissières, objectif de cours à 12 mois, potentiel de hausse
- Achat fort 5 31,2%
- Achat 9 56,2%
- Conserver 2 12,5%
- Vente 0 0,0%
- Vente forte 0 0,0%
Objectif de cours à 12 mois
8 analystes · 2026-08-15Historique des bénéfices BPA réel vs estimation, surprise %, taux de succès, prochaine date de publication des résultats
| Période | EPS Actual | BPA est. | Surprise |
|---|---|---|---|
| 30 juin 2026 | $-2.85 | $-0.55 | -2.3% |
| 31 mars 2026 | $-0.47 | $-0.47 | 0.00% |
| 31 décembre 2025 | $-0.40 | $-0.54 | 0.14% |
| 30 septembre 2025 | $-0.52 | $-0.63 | 0.11% |
| 30 juin 2025 | $-0.66 | $-0.73 | 0.07% |
| 31 mars 2025 | $-0.79 | $-1.00 | 0.21% |
Comparaison des pairs (sous-secteur GICS) Indicateurs clés par rapport aux pairs du secteur
| Ticker | Capitalisation Boursière | P/E | Revenus Année/Année | Marge Nette | ROE | Marge Brute |
|---|---|---|---|---|---|---|
| MLYS | $2.96B | -15.8 | — | — | -32.2% | — |
| COAG | — | — | — | — | — | — |
| KLRA | — | — | — | — | — | — |
| CDNA | $959M | -47.1 | 13.8% | -5.6% | -6.8% | — |
| PGEN | $1.48B | -3.1 | 146.7% | -2588.2% | 3159.1% | — |
| VERA | — | -10.9 | — | — | -55.9% | — |
| VCEL | $1.82B | 112.5 | 16.4% | 6.0% | 5.0% | 74.4% |
| PVLA | $1.30B | -28.2 | 65.3% | -1610.6% | -110.1% | — |
| BHVN | $1.50B | -1.6 | — | — | -310.8% | — |
| ADMA | $4.34B | 30.4 | 19.6% | 28.8% | 33.6% | 57.4% |
Fondamentaux complets Tous les indicateurs par an — compte de résultat, bilan, flux de trésorerie
Compte de résultat 12
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| R&D Expense | $132M | $169M | $70M | $26M | |
| SG&A Expense | $39M | $24M | $14M | $5M | |
| Operating Expenses | $171M | $192M | $85M | $31M | |
| Operating Income | $-171M | $-192M | $-85M | $-31M | |
| Other Non-op | $0 | $5.0K | $3.0K | $2M | |
| Income Tax | $0 | · | · | · | |
| Net Income | $-155M | $-178M | $-72M | $-30M | |
| EPS (Basic) | $-2.29 | $-3.66 | $-1.99 | $-5.77 | |
| EPS (Diluted) | $-2.29 | $-3.66 | $-1.99 | $-5.77 | |
| Shares (Basic) | 67,656,355 | 48,539,795 | 36,188,254 | 5,167,296 | |
| Shares (Diluted) | 67,656,355 | 48,539,795 | 36,188,254 | 5,167,296 | |
| EBITDA | $-171M | $-192M | $-85M | · |
Bilan 16
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $173M | $114M | $49M | $88M | |
| Prepaid Expense | $5M | $7M | $13M | $3M | |
| Current Assets | $661M | $205M | $249M | $113M | |
| PP&E (Net) | $38.0K | $53.0K | $0 | · | |
| Other Non-current Assets | $382.0K | $499.0K | $51.0K | $2M | |
| Total Assets | $662M | $206M | $252M | $114M | |
| Accounts Payable | $2M | $479.0K | $601.0K | $2M | |
| Accrued Liabilities | $13M | $14M | $10M | $6M | |
| Current Liabilities | $15M | $15M | $10M | $8M | |
| Total Liabilities | $15M | · | · | · | |
| Common Stock | $8.0K | $5.0K | $4.0K | $1.0K | |
| Paid-in Capital | $1.10B | $494M | $366M | $540.0K | |
| Retained Earnings | $-457M | $-303M | $-125M | $-53M | |
| Stockholders' Equity | $647M | $191M | $241M | $-52M | |
| Liabilities + Equity | $662M | $206M | $252M | $114M | |
| Shares Outstanding | 81,536,557 | 49,821,915 | 41,133,916 | 6,419,238 |
Flux de trésorerie 10
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| D&A | $59.0K | $43.0K | $0 | · | |
| Stock-based Comp | $19M | $11M | $5M | $455.0K | |
| Deferred Tax | $0 | $0 | $0 | $0 | |
| Other Non-cash | $-7M | $117.0K | · | · | |
| Operating Cash Flow | $-142M | $-166M | $-81M | $-29M | |
| CapEx | $15.0K | $96.0K | $0 | · | |
| Investing Cash Flow | $-390M | $115M | $-160M | $-22M | |
| Financing Cash Flow | $591M | $116M | $203M | $128M | |
| Net Change in Cash | $59M | $65M | $-38M | $77M | |
| Free Cash Flow | $-142M | $-166M | · | · |
Rentabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| ROA | -35.6% | -77.7% | -39.3% | · | |
| ROE | -32.2% | -83.0% | -28.5% | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 43.8 | 14.0 | 23.8 | · | |
| Quick Ratio | 11.4 | 7.8 | 4.7 | · |
Valorisation (TTM) 8
| Métrique | Tendance | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Net Income TTM | $-155M | $-178M | $-72M | $-30M | |
| Market Cap | $2.96B | $613M | $354M | · | |
| P/E | -15.8 | -3.4 | -4.3 | · | |
| P/B | 4.6 | 3.2 | 1.5 | · | |
| P / Tangible Book | 4.6 | 3.2 | 1.5 | · | |
| P / Cash Flow | -20.8 | -3.7 | -4.4 | · | |
| P / FCF | -20.8 | -3.7 | · | · | |
| Earnings Yield | -6.3% | -29.7% | -23.1% | · |
Compte de résultat 12
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $221M | $24M | $24M | $31M | $38M | $38M | $45M | $54M | $39M | $31M | $24M | $22M | $12M | $12M | $8M | |
| SG&A Expense | $25M | $21M | $14M | $10M | $8M | $7M | $7M | $6M | $6M | $5M | $4M | $4M | $4M | $3M | $2M | |
| Operating Expenses | $246M | $45M | $38M | $41M | $47M | $44M | $52M | $60M | $45M | $35M | $28M | $26M | $16M | $15M | $10M | |
| Operating Income | $-246M | $-45M | $-38M | $-41M | $-47M | $-44M | $-52M | $-60M | $-45M | $-35M | $-28M | $-26M | $-16M | $-15M | $-10M | |
| Other Non-op | $13.0K | $5.0K | $1.0K | $4.0K | $-2.0K | $-3.0K | $12.0K | $-10.0K | $2.0K | $1.0K | $-6M | $0 | $4M | $2M | $935.0K | |
| Income Tax | · | · | $0 | · | · | · | · | · | · | · | · | · | · | · | · | |
| Net Income | $-241M | $-39M | $-32M | $-37M | $-43M | $-42M | $-49M | $-56M | $-41M | $-32M | $-24M | $-23M | $-12M | $-13M | $-9M | |
| EPS (Basic) | $-2.85 | $-0.47 | $-0.32 | $-0.52 | $-0.66 | $-0.79 | $-1.00 | $-1.13 | $-0.83 | $-0.70 | $-0.60 | $-0.57 | $-0.31 | $-0.51 | $-1.74 | |
| EPS (Diluted) | $-2.85 | $-0.47 | $-0.32 | $-0.52 | $-0.66 | $-0.79 | $-1.00 | $-1.13 | $-0.83 | $-0.70 | $-0.60 | $-0.57 | $-0.31 | $-0.51 | $-1.74 | |
| Shares (Basic) | 84,727,282 | 82,834,752 | -121,552,997 | 70,594,504 | 65,451,297 | 53,163,551 | -95,532,433 | 49,815,186 | 49,356,287 | 44,900,755 | -68,261,944 | 39,930,748 | 39,754,981 | 24,764,469 | -10,290,323 | |
| Shares (Diluted) | 84,727,282 | 82,834,752 | -121,552,997 | 70,594,504 | 65,451,297 | 53,163,551 | -95,532,433 | 49,815,186 | 49,356,287 | 44,900,755 | -68,261,944 | 39,930,748 | 39,754,981 | 24,764,469 | -10,290,323 | |
| EBITDA | $-246M | $-45M | · | $-41M | $-47M | $-44M | · | $-60M | $-45M | $-35M | · | $-26M | $-16M | $-15M | · |
Bilan 17
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $138M | $113M | $173M | $218M | $102M | $165M | $114M | $97M | $68M | $90M | $49M | $86M | $101M | $138M | $88M | |
| Prepaid Expense | $4M | $6M | $5M | $6M | $10M | $11M | $7M | $4M | $7M | $8M | $13M | $12M | $8M | $5M | $3M | |
| Current Assets | $666M | $652M | $661M | $600M | $335M | $355M | $205M | $268M | $318M | $347M | $249M | $265M | $269M | $275M | $113M | |
| PP&E (Net) | $27.0K | $32.0K | $38.0K | $7.0K | $22.0K | $38.0K | $53.0K | $69.0K | $42.0K | $51.0K | $0 | · | · | · | · | |
| Other Non-current Assets | $2M | $360.0K | $382.0K | $144.0K | $433.0K | $397.0K | $499.0K | $452.0K | $449.0K | $379.0K | $51.0K | $51.0K | $51.0K | $39.0K | $2M | |
| Total Assets | $668M | $653M | $662M | $600M | $336M | $355M | $206M | $268M | $318M | $347M | $252M | $278M | $291M | $306M | $114M | |
| Accounts Payable | $1M | $1M | $2M | $1M | $3M | $373.0K | $479.0K | $3M | $2M | $4M | $601.0K | $6M | $2M | $2M | $2M | |
| Accrued Liabilities | $18M | $14M | $13M | $22M | $19M | $13M | $14M | $28M | $27M | $15M | $10M | $8M | $4M | $8M | $6M | |
| Current Liabilities | $19M | $15M | $15M | $24M | $22M | $13M | $15M | $31M | $28M | $19M | $10M | $14M | $6M | $11M | $8M | |
| Total Liabilities | $117M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Long-term Debt | $100.0K | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Common Stock | $9.0K | $8.0K | $8.0K | $8.0K | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $1.0K | |
| Paid-in Capital | $1.29B | $1.13B | $1.10B | $1.00B | $702M | $686M | $494M | $490M | $487M | $484M | $366M | $364M | $363M | $361M | $540.0K | |
| Retained Earnings | $-738M | $-497M | $-457M | $-425M | $-388M | $-345M | $-303M | $-254M | $-197M | $-156M | $-125M | $-100M | $-78M | $-65M | $-53M | |
| Stockholders' Equity | $551M | $638M | $647M | $576M | $314M | $342M | $191M | $237M | $290M | $328M | $241M | $264M | $285M | $296M | $-52M | |
| Liabilities + Equity | $668M | $653M | $662M | $600M | $336M | $355M | $206M | $268M | $318M | $347M | $252M | $278M | $291M | $306M | $114M | |
| Shares Outstanding | 88,351,196 | 82,454,950 | 81,536,557 | 78,969,459 | 65,725,409 | 64,876,228 | 49,821,915 | 49,755,946 | 49,710,598 | 49,632,989 | 41,133,916 | 41,105,118 | 40,856,653 | 40,856,653 | 6,419,238 |
Flux de trésorerie 11
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $5.0K | $6.0K | $13.0K | $15.0K | $16.0K | $15.0K | $15.0K | $11.0K | $9.0K | $8.0K | $0 | $0 | $0 | $0 | · | |
| Stock-based Comp | $7M | $7M | $5M | $6M | $5M | $4M | $3M | $3M | $3M | $2M | $1M | $2M | $1M | $749.0K | $218.0K | |
| Other Non-cash | · | $-7M | · | · | · | $-7M | · | · | · | $10M | · | · | · | · | · | |
| Operating Cash Flow | $-33M | $-39M | $-38M | $-29M | $-30M | $-45M | $-67M | $-50M | $-30M | $-19M | $-29M | $-19M | $-20M | $-13M | $-10M | |
| CapEx | · | · | $15.0K | $0 | $0 | $0 | $0 | $37.0K | $0 | $59.0K | $0 | $0 | $0 | $0 | · | |
| Investing Cash Flow | $-185M | $-45M | $-103M | $-151M | $-43M | $-93M | $84M | $80M | $8M | $-56M | $-8M | $4M | $-16M | $-140M | $50M | |
| Stock Issued | · | · | · | · | · | $189M | · | · | · | $0 | · | $0 | $-581.0K | $204M | · | |
| Net Stock Activity | · | · | · | · | · | $189M | · | · | · | · | · | · | · | $204M | · | |
| Financing Cash Flow | $243M | $24M | $97M | $295M | $10M | $189M | $90.0K | $-1.0K | $-152.0K | $116M | $74.0K | $184.0K | $-581.0K | $204M | $-1M | |
| Net Change in Cash | $25M | $-60M | $-45M | $116M | $-63M | $51M | $17M | $29M | $-23M | $41M | $-37M | $-15M | $-37M | $51M | $39M | |
| Free Cash Flow | · | · | · | · | · | $-45M | · | · | · | $-19M | · | · | · | · | · |
Rentabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -48.0% | -7.8% | · | -8.5% | -13.2% | -12.0% | · | -20.6% | -13.5% | -9.6% | · | -16.4% | -8.3% | -8.2% | · | |
| ROE | -55.8% | -8.0% | · | -9.1% | -14.3% | -12.6% | · | -22.5% | -14.3% | -10.1% | · | -17.2% | -8.5% | -8.5% | · |
Liquidité et Solvabilité 2
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 34.5 | 44.3 | · | 25.5 | 15.1 | 26.5 | · | 8.5 | 11.2 | 18.1 | · | 19.6 | 43.4 | 26.1 | · | |
| Quick Ratio | 7.2 | 7.7 | · | 9.3 | 4.6 | 12.3 | · | 3.1 | 2.4 | 4.7 | · | 6.4 | 16.3 | 13.1 | · |
Valorisation (TTM) 8
| Métrique | Tendance | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-361M | $-162M | · | $-179M | $-183M | $-171M | · | $-152M | $-107M | $-79M | · | $-54M | $-38M | $-33M | · | |
| Market Cap | $2.38B | $2.23B | · | $2.99B | $889M | $1.03B | · | $603M | $582M | $641M | · | $391M | $697M | $640M | · | |
| P/E | -6.0 | -11.1 | · | -12.2 | -4.0 | -4.6 | · | -3.7 | -4.9 | -6.2 | · | -3.5 | -5.1 | -3.4 | · | |
| P/B | 4.3 | 3.5 | · | 5.2 | 2.8 | 3.0 | · | 2.5 | 2.0 | 2.0 | · | 1.5 | 2.4 | 2.2 | · | |
| P / Tangible Book | 4.3 | 3.5 | · | 5.2 | 2.8 | 3.0 | · | 2.5 | 2.0 | 2.0 | · | 1.5 | 2.4 | 2.2 | · | |
| P / Cash Flow | · | -56.6 | · | · | · | -22.6 | · | · | · | -33.5 | · | · | · | -50.1 | · | |
| P / FCF | · | · | · | · | · | -22.6 | · | · | · | -33.4 | · | · | · | · | · | |
| Earnings Yield | -16.7% | -9.0% | · | -8.2% | -25.2% | -21.7% | · | -26.7% | -20.6% | -16.2% | · | -28.2% | -19.8% | -29.0% | · |
États financiers Compte de résultat, bilan, flux de trésorerie — annuel, sur les 5 dernières années
Compte de résultat
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Résultat net | $-155M | $-178M | $-72M | $-30M |
| BPA dilué | $-2.29 | $-3.66 | $-1.99 | $-5.77 |
Bilan
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Ratio de liquidité | 43.8 | 14.0 | 23.8 | — |
| Ratio de liquidité réduite | 11.4 | 7.8 | 4.7 | — |
Flux de trésorerie
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Flux de trésorerie libre | $-142M | $-166M | — | — |
Dernières actualités Actualités récentes mentionnant cette entreprise
Signaux de trading Signaux d'achat/vente récents avec prix d'entrée et ratio risque/récompense
Mes métriques Votre watchlist personnelle — lignes sélectionnées de Fondamentaux Complets
Choisissez les indicateurs qui vous importent — cliquez sur le ➕ à côté de n'importe quelle ligne dans Fondamentaux Complets ci-dessus.
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Détenteurs institutionnels (13F) 250 déclarants · $2.4B total · Au 30 juin 2026
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Nouvelles positions | Positions clôturées | Augmenté | Diminué | Variation nette des actions |
|---|---|---|---|---|
| 46 (+15 vs T. préc.) | 21 (-15 vs T. préc.) | 79 (-19 vs T. préc.) | 66 (+13 vs T. préc.) | +6.7M |
Comparé à Q1 2026. Les dépôts de formulaire 13F de la SEC sont dus dans les 45 jours suivant la fin du trimestre, plus une courte période tampon pour les déposants tardifs — les trimestres encore dans cette fenêtre sont ignorés au profit de la paire la plus récente entièrement déclarée.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Catalys Pacific, LLC | $213 245 549 | 7 903 838 | 9,02% | Actions |
| RA CAPITAL MANAGEMENT, L.P. | $207 550 395 | 7 692 750 | 8,78% | Actions |
| SAMSARA BIOCAPITAL, LLC | $158 400 066 | 5 871 018 | 6,70% | Actions |
| STATE STREET CORP | $111 741 339 | 4 141 636 | 4,73% | Actions |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $106 786 840 | 3 958 000 | 4,52% | Actions |
| FMR LLC | $101 995 543 | 3 780 413 | 4,31% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $74 377 655 | 2 756 770 | 3,15% | Actions |
| Laurion Capital Management LP | $67 615 981 | 2 506 152 | 2,86% | Actions |
| ORBIMED ADVISORS LLC | $56 935 894 | 2 110 300 | 2,41% | Actions |
| Capital World Investors | $53 895 437 | 1 997 607 | 2,28% | Actions |
| ARMISTICE CAPITAL, LLC | $46 837 280 | 1 736 000 | 1,98% | Actions |
| Troluce Capital Advisors LLC | $46 641 756 | 1 728 753 | 1,97% | Actions |
| ANDERA PARTNERS | $42 949 921 | 1 591 917 | 1,82% | Actions |
| SR One Capital Management, LP | $42 195 803 | 1 563 966 | 1,78% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $39 659 818 | 1 469 971 | 1,68% | Actions |
| Pictet Asset Management Holding SA | $38 598 910 | 1 430 649 | 1,63% | Actions |
| Polar Capital Holdings Plc | $38 334 641 | 1 420 854 | 1,62% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $36 657 036 | 1 358 375 | 1,55% | Actions |
| BANK OF AMERICA CORP /DE/ | $36 365 479 | 1 347 868 | 1,54% | Actions |
| MILLENNIUM MANAGEMENT LLC | $32 963 031 | 1 221 758 | 1,39% | Actions |
| GOLDMAN SACHS GROUP INC | $30 925 016 | 1 146 220 | 1,31% | Actions |
| Ghisallo Capital Management LLC | $30 352 500 | 1 125 000 | 1,28% | Actions |
| ALLIANCEBERNSTEIN L.P. | $28 919 686 | 1 067 541 | 1,22% | Actions |
| Logos Global Management LP | $28 329 000 | 1 050 000 | 1,20% | Actions |
| ARMISTICE CAPITAL, LLC | $28 059 200 | 1 040 000 | 1,19% | Option d'achat |
| AMERICAN CENTURY COMPANIES INC | $27 972 049 | 1 036 767 | 1,18% | Actions |
| Davern Capital Partners, LP | $23 169 156 | 858 753 | 0,98% | Actions |
| Candriam S.C.A. | $23 100 611 | 857 037 | 0,98% | Actions |
| Caption Management, LLC | $22 976 168 | 851 600 | 0,97% | Option de vente |
| Nantahala Capital Management, LLC | $22 136 577 | 820 481 | 0,94% | Actions |
| Affinity Asset Advisors, LLC | $20 235 000 | 750 000 | 0,86% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20 171 786 | 747 657 | 0,85% | Actions |
| TUDOR INVESTMENT CORP ET AL | $19 921 223 | 738 370 | 0,84% | Actions |
| Aberdeen Group plc | $18 595 560 | 689 235 | 0,79% | Actions |
| ALGERT GLOBAL LLC | $17 510 748 | 649 027 | 0,74% | Actions |
| Catalio Capital Management, LP | $17 502 520 | 648 722 | 0,74% | Actions |
| Pale Fire Capital SE | $16 573 382 | 614 284 | 0,70% | Actions |
| STEMPOINT CAPITAL LP | $16 260 468 | 602 686 | 0,69% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $14 062 408 | 521 216 | 0,59% | Actions |
| VANGUARD GROUP INC | $13 436 227 | 370 246 | 0,57% | Actions |
| Rock Springs Capital Management LP | $13 083 978 | 484 951 | 0,55% | Actions |
| TWO SIGMA ADVISERS, LP | $12 835 773 | 353 700 | 0,54% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $12 468 106 | 462 124 | 0,53% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $12 162 476 | 450 796 | 0,51% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $12 150 983 | 450 370 | 0,51% | Actions |
| Integral Health Asset Management, LLC | $12 141 000 | 450 000 | 0,51% | Actions |
| Prosight Management, LP | $12 135 469 | 449 795 | 0,51% | Actions |
| Rhenman & Partners Asset Management AB | $11 233 690 | 416 371 | 0,48% | Actions |
| Caption Management, LLC | $11 145 087 | 413 087 | 0,47% | Actions |
| JENNISON ASSOCIATES LLC | $10 326 514 | 382 747 | 0,44% | Actions |
| Parkman Healthcare Partners LLC | $10 261 951 | 380 354 | 0,43% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $10 206 534 | 378 300 | 0,43% | Actions |
| CenterBook Partners LP | $9 864 697 | 365 630 | 0,42% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $9 593 279 | 355 570 | 0,41% | Actions |
| Iron Triangle Partners LP | $9 329 615 | 257 085 | 0,39% | Actions |
| TimesSquare Capital Management, LLC | $9 178 038 | 338 798 | 0,39% | Actions |
| MORGAN STANLEY | $8 465 685 | 313 776 | 0,36% | Actions |
| Eversept Partners, LP | $8 355 409 | 309 689 | 0,35% | Actions |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $8 251 407 | 306 972 | 0,35% | Actions |
| ADAR1 Capital Management, LLC | $8 063 944 | 298 886 | 0,34% | Actions |
| Longaeva Partners L.P. | $7 584 186 | 281 104 | 0,32% | Actions |
| Qube Research & Technologies Ltd | $6 738 956 | 249 776 | 0,28% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4 818 628 | 178 600 | 0,20% | Option de vente |
| MONTANOVA CAPITAL, LLC | $4 691 444 | 173 886 | 0,20% | Actions |
| Trexquant Investment LP | $4 578 911 | 169 715 | 0,19% | Actions |
| TWO SIGMA INVESTMENTS, LP | $4 372 972 | 162 082 | 0,18% | Actions |
| Brevan Howard Capital Management LP | $4 147 420 | 153 722 | 0,18% | Actions |
| Burkehill Global Management, LP | $4 047 000 | 150 000 | 0,17% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $3 976 906 | 147 402 | 0,17% | Actions |
| Caption Management, LLC | $3 879 724 | 143 800 | 0,16% | Option d'achat |
| Artia Global Partners LP | $3 717 844 | 137 800 | 0,16% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3 609 924 | 133 800 | 0,15% | Option d'achat |
| Ensign Peak Advisors, Inc | $3 193 946 | 118 382 | 0,14% | Actions |
| 22NW, LP | $3 071 403 | 113 840 | 0,13% | Actions |
| BlackRock, Inc. | $3 036 896 | 112 561 | 0,13% | Actions |
| Swiss National Bank | $3 010 968 | 111 600 | 0,13% | Actions |
| Ishara Investments LP | $2 765 450 | 102 500 | 0,12% | Actions |
| MARK ASSET MANAGEMENT LP | $2 732 777 | 101 289 | 0,12% | Actions |
| ExodusPoint Capital Management, LP | $2 726 383 | 101 052 | 0,12% | Actions |
| CITIGROUP INC | $2 590 620 | 96 020 | 0,11% | Actions |
| Schonfeld Strategic Advisors LLC | $2 569 628 | 95 242 | 0,11% | Actions |
| ALPS ADVISORS INC | $2 400 572 | 88 976 | 0,10% | Actions |
| CITADEL ADVISORS LLC | $2 349 553 | 87 085 | 0,10% | Actions |
| Squarepoint Ops LLC | $2 329 102 | 86 327 | 0,10% | Actions |
| HighVista Strategies LLC | $2 322 573 | 86 085 | 0,10% | Actions |
| BlueCrest Capital Management Ltd | $2 297 536 | 85 157 | 0,10% | Actions |
| KVP Capital Advisors, LP | $2 270 853 | 84 168 | 0,10% | Actions |
| Rafferty Asset Management, LLC | $2 109 458 | 78 186 | 0,09% | Actions |
| CITADEL ADVISORS LLC | $2 045 084 | 75 800 | 0,09% | Option d'achat |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 976 690 | 73 265 | 0,08% | Actions |
| JANE STREET GROUP, LLC | $1 912 882 | 70 900 | 0,08% | Option d'achat |
| RHUMBLINE ADVISERS | $1 894 120 | 70 205 | 0,08% | Actions |
| JANE STREET GROUP, LLC | $1 702 438 | 63 100 | 0,07% | Option de vente |
| PFM Health Sciences, LP | $1 684 038 | 62 418 | 0,07% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $1 659 696 | 61 266 | 0,07% | Actions |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $1 598 349 | 59 242 | 0,07% | Actions |
| D. E. Shaw & Co., Inc. | $1 554 075 | 57 601 | 0,07% | Actions |
| DIADEMA PARTNERS LP | $1 520 242 | 56 347 | 0,06% | Actions |
| CITADEL ADVISORS LLC | $1 419 148 | 52 600 | 0,06% | Option de vente |
| CANADA PENSION PLAN INVESTMENT BOARD | $1 386 772 | 51 400 | 0,06% | Actions |
Initiés de la société 6 initiés · 2 dirigeants · 2 administrateurs
| Dirigeant | Rôle | Dernière activité | Actions détenues | Achats 12m | Ventes 12m | Net 12m |
|---|---|---|---|---|---|---|
| Jon Congleton | Chief Executive Officer | 13 juillet 2026 S | 603 621 | 0 | 3 | $-2 251 928 |
| Eric Warren | Chief Commercial Officer | 21 juillet 2026 M | 38 400 | 0 | 2 | $-2 896 671 |
| Daphne Karydas | Administrateur | 17 juin 2026 M | 6 200 | 0 | 1 | $-75 000 |
| HBM Healthcare Investments (Cayman) Ltd. | Détenteur de 10% | 14 février 2023 C | 3 218 106 | 0 | 0 | $0 |
| James J. Ferguson III | — | 10 août 2026 A | 102 400 | 0 | 0 | $0 |
| David Malcom Rodman | — | 10 août 2026 M | 51 384 | 0 | 9 | $-1 248 532 |
Initiés issus des déclarations SEC Form 3/4/5 ; net = uniquement P/S de marché
Activistes et détenteurs de 5%+ 2 participations
Investisseurs ayant déposé un Schedule 13D auprès de la SEC — détention effective supérieure à 5% avec l'intention d'influencer l'émetteur (participations activistes, campagnes pour le conseil d'administration, fusions-acquisitions). Chaque ligne montre le dernier état connu de la position du déposant.
| Déclarant | Déposé | Participation | Statut | Objectif | Dépôt |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×4 dépôts | 8 septembre 2025 | 9,90% | Amendement | — | SEC |
| Samsara BioCapital, L.P., Samsara BioCapital GP, LLC, Samsara Opportunity Fund, L.P., Samsara Opportunity Fund GP, LLC, Srinivas Akkaraju ×4 dépôts | 8 septembre 2025 | 8,20% | Amendement | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Détention d'ETF Détenu par 41 ETFs
Le poids reflète uniquement les participations directes en actions (N-PORT) ; les fonds à effet de levier ou basés sur des dérivés peuvent détenir une exposition supplémentaire aux swaps non indiquée.
| Fonds | Poids | Unités | Au | Source |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1,59% | 81 578 NS | 31 mai 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,53% | 7 478 NS | 30 avril 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,52% | 101 556 NS | 30 avril 2026 | N-PORT |
| ESSC · Strategy Shares | 0,16% | 1 539 NS | 30 avril 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,15% | 4 490 SH | 8 août 2026 | Quotidien |
| IBB · iShares Trust | 0,13% | 445 700 SH | 8 août 2026 | Quotidien |
| BIB · ProShares Trust | 0,13% | 2 925 NS | 31 mai 2026 | N-PORT |
| IWO · iShares Trust | 0,10% | 521 091 SH | 8 août 2026 | Quotidien |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,09% | 61 529 SH | 8 août 2026 | Quotidien |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,07% | 19 142 NS | 30 avril 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,07% | 33 115 NS | 30 avril 2026 | N-PORT |
| SMLF · iShares Trust | 0,06% | 92 257 SH | 8 août 2026 | Quotidien |
| BKSE · BNY Mellon ETF Trust | 0,06% | 1 696 NS | 30 avril 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,05% | 330 253 SH | 8 août 2026 | Quotidien |
| IWM · iShares Trust | 0,05% | 1 464 927 SH | 8 août 2026 | Quotidien |
| ESML · iShares Trust | 0,05% | 51 632 SH | 8 août 2026 | Quotidien |
| ISCG · iShares Trust | 0,05% | 17 151 SH | 8 août 2026 | Quotidien |
| VFMO · VANGUARD WELLINGTON FUND | 0,04% | 29 046 SH | 8 août 2026 | Quotidien |
| RSSL · Global X Funds | 0,04% | 20 663 NS | 30 avril 2026 | N-PORT |
| ITWO · ProShares Trust | 0,04% | 2 245 NS | 31 mai 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,04% | 267 668 NS | 31 mai 2026 | N-PORT |
| ISCB · iShares Trust | 0,02% | 2 439 SH | 8 août 2026 | Quotidien |
| UWM · ProShares Trust | 0,02% | 1 757 NS | 31 mai 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,02% | 728 233 SH | 8 août 2026 | Quotidien |
| VHT · VANGUARD WORLD FUND | 0,02% | 167 502 SH | 8 août 2026 | Quotidien |
| FHLC · FIDELITY COVINGTON TRUST | 0,02% | 20 978 NS | 30 avril 2026 | N-PORT |
| URTY · ProShares Trust | 0,02% | 1 777 NS | 31 mai 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 2 737 SH | 8 août 2026 | Quotidien |
| DFAS · Dimensional ETF Trust | 0,01% | 49 031 NS | 30 avril 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 1 918 NS | 31 mai 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,01% | 7 921 SH | 8 août 2026 | Quotidien |
| HDG · ProShares Trust | 0,01% | 45 NS | 31 mai 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 22 197 NS | 31 mai 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 92 521 SH | 8 août 2026 | Quotidien |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 35 158 NS | 31 mai 2026 | N-PORT |
| TILT · FlexShares Trust | 0,00% | 1 540 NS | 30 avril 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 11 075 SH | 8 août 2026 | Quotidien |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,00% | 466 NS | 31 mai 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 968 124 SH | 8 août 2026 | Quotidien |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 4 746 SH | 8 août 2026 | Quotidien |
| FTLS · First Trust Exchange-Traded Fund III | -0,03% | -28 739 NS | 30 avril 2026 | N-PORT |