DFTX Definium Therapeutics, Inc. - Common Shares
About Definium Therapeutics, Inc. - Common Shares Company overview from Wikipedia
Definium Therapeutics, Inc., formerly known as MindMed, is a New York-based biotechnology company that is currently developing clinical and therapeutic applications for psychedelic and, more broadly, psychoplastogenic drugs.
Read more
Definium Therapeutics, Inc., formerly known as MindMed, is a New York-based biotechnology company that is currently developing clinical and therapeutic applications for psychedelic and, more broadly, psychoplastogenic drugs.
History
MindMed was founded in May 2019 by Stephen Hurst and Jamon Rahn.
MindMed initially focused on developing treatments for opioid withdrawal and opioid use disorder with 18-MC, a non-hallucinogenic molecule based on the psychoactive alkaloid ibogaine. In June 2019, it acquired the 18-MC drug development program, previously funded by the National Institute on Drug Abuse, and in September began to prepare 18-MC for a Phase I FDA clinical trial to enable further clinical trials targeting opioid withdrawal and opioid use disorder.
MindMed was the first psychedelic pharmaceutical company to go public, listing on the Canadian NEO Exchange in March of 2020 through a reverse takeover with the Canadian gold mining company Broadway Gold Mining. It began trading on the Nasdaq as MNMD in April 2021 after being approved for an uplisting from the OTC Markets.
In a press release on June 9, 2021 MindMed announced that Jamon Rahn was stepping down both as the CEO and as a director on the board, to be replaced by then CDO Robert Barrow.
On February 26, 2021, MindMed closed its acquisition of digital health startup HealthMode. In connection with the acquisition, Daniel Karlin MD, CEO of HealthMode, was appointed to the position of CMO of the company.
On August 25, 2022, the first patient was dosed in a phase 2b trial for treatment of MM120 (now DT120) in generalized anxiety disorder (GAD). The study would go on to recruit 198 participants. The majority of trial participants experienced statistically significant improvements in their GAD scores, leading to the approval of multiple phase three human trials.
On January 12, 2026, MindMed rebranded to Definium Therapeutics.
Research
In March 2020, MindMed announced that it had partnered with NYU Langone to launch a clinical training program to train psychiatrists in psychedelic therapies and research to advance and deploy psychedelic medicines. The company committed $5 million to establish the center, which will also explore 18-MC and the use of drugs, including psilocybin-assisted therapy for alcohol use disorder.
In April 2020, the company entered into a long-term partnership with University Hospital Basel's Liechti Lab, gaining rights to more than ten years of the lab's data related to LSD, MDMA, and other psychedelic substances. The development of a novel compound designed to shorten the duration or stop an LSD experience that would allow LSD to be more widely used in a therapeutic environment was subsequently announced. Later that year a clinical trial studying the effects of DMT, the primary psychoactive ingredient in ayahuasca, and clinical trials combining MDMA and LSD were announced. A study to better understand and compare the altered states of consciousness induced by psilocybin and LSD began in August 2020,
and in October a Phase 1 study at the Liechti Lab on the acute dose dependent effects of LSD was completed. The results of the study were published by the American College of Neuropsychopharmacology in the journal Neuropsychopharmacology. In September 2021, further results were presented by Matthias Liechti, head of the Liechti Lab, at the INSIGHT Conference in Berlin. The results included the first clinical evidence on the comparative effects of LSD and psilocybin, stating 100mcg of LSD produced the same acute perceptual effects as a dose of 20 mg of psilocybin in healthy volunteers. Additionally, psilocybin taken after administering antidepressants for two weeks prior, was deemed safe, as well as reduced anxiety and blood pressure without hindering the psychedelic experience.
In December 2020, MindMed entered into an investigator-sponsored study agreement with Maastricht University in the Netherlands. The university provided facilities and personnel for a Phase 1 study to evaluate the effects of two low doses of LSD on mood, sleep and neuroplasticity.
In March 2024, the FDA granted breakthrough therapy designation to MindMed's form of LSD (MM120; now DT120) for the treatment of generalized anxiety disorder. This decision was influenced by a drug trial in which approximately half of the participants experienced significant relief from their symptoms. Positive results in clinical trials against general depression symptoms and generalized anxiety disorder were reported in 2026.
=== Ongoing clinical trials ===
Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗
DFTX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
DFTX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
10-Year Performance Revenue, net income, margins and EPS trends
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Financial Health Debt, liquidity, solvency — balance sheet strength
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
DFTX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
- Strong Buy 8 34.8%
- Buy 14 60.9%
- Hold 1 4.3%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
16 analysts · 2026-08-16Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| June 30, 2026 | $-1.44 | $-0.56 | -0.88% |
| March 31, 2026 | $-0.71 | $-0.50 | -0.21% |
| Dec. 31, 2025 | $-0.50 | $-0.50 | -0.00% |
| Sept. 30, 2025 | $-0.78 | $-0.51 | -0.27% |
| June 30, 2025 | $-0.50 | $-0.37 | -0.13% |
| March 31, 2025 | $-0.27 | $-0.37 | 0.10% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| DFTX | $1.32B | -6.5 | 212.0% | — | -71.0% | — |
| AXSM | $9.29B | -49.6 | 65.5% | -28.7% | -227.0% | — |
| CRNX | $4.45B | -9.4 | 640.7% | -6046.2% | -43.0% | — |
| LQDA | $3.01B | -43.1 | 1031.2% | -43.5% | -230.0% | — |
| BLTE | — | — | — | — | — | — |
| AMRX | — | 57.3 | 8.1% | 2.4% | -80.0% | 36.9% |
| LGND | $3.74B | 30.8 | 60.4% | 46.4% | 13.5% | — |
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| MANE | — | — | — | — | 82.6% | — |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| LLY | — | 46.8 | 44.7% | 31.7% | 101.2% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $118M | $65M | $52M | $36M | $35M | $19M | |
| SG&A Expense | $49M | $39M | $42M | $30M | $59M | $14M | |
| Operating Expenses | $166M | $104M | $94M | $66M | $94M | $33M | |
| Operating Income | $-166M | $-104M | $-94M | $-66M | $-94M | $-33M | |
| Interest Expense | $5M | $2M | $920.0K | · | · | · | |
| Other Non-op | $-17M | $-5M | $-2M | $10M | $-339.0K | $-907.0K | |
| Pretax Income | $-184M | $-109M | $-96M | $-57M | $-94M | $-34M | |
| Income Tax | $0 | · | · | · | $-1M | · | |
| Net Income | $-184M | $-109M | $-96M | $-57M | $-93M | $-34M | |
| EPS (Basic) | $-2.06 | $-1.54 | $-2.44 | $-1.84 | $-3.40 | · | |
| EPS (Diluted) | $-2.06 | $-1.54 | $-2.44 | $-1.84 | $-3.40 | · | |
| Shares (Basic) | 89,327,608 | 70,461,067 | 39,157,420 | 30,857,463 | 27,377,082 | · | |
| Shares (Diluted) | 89,327,608 | 70,461,067 | 39,157,420 | 30,857,463 | 27,377,082 | · | |
| EBITDA | $-166M | $-104M | $-94M | $-66M | $-94M | · |
Balance Sheet 20
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $258M | $274M | $100M | $142M | $134M | $80M | |
| Short-term Investments | $154M | $0 | · | · | · | · | |
| Prepaid Expense | $8M | $8M | $4M | $4M | $4M | $1M | |
| Current Assets | $419M | $282M | $104M | $146M | $137M | $82M | |
| Goodwill | $20M | $20M | $20M | $20M | $20M | $0 | |
| Intangibles | · | $0 | $527.0K | $4M | $7M | · | |
| Other Non-current Assets | $862.0K | $613.0K | $224.0K | $331.0K | · | · | |
| Total Assets | $440M | $302M | $125M | $170M | $164M | $82M | |
| Accounts Payable | $5M | $2M | $4M | $2M | $4M | $2M | |
| Accrued Liabilities | $20M | $13M | $12M | $6M | $6M | $986.0K | |
| Current Liabilities | $67M | $39M | $32M | $18M | $10M | $3M | |
| Other Non-current Liabilities | $496.0K | · | $32.0K | $1M | $2M | · | |
| Total Liabilities | $108M | $61M | $46M | $19M | $12M | $6M | |
| Total Debt | $41M | $22M | $14M | · | · | · | |
| Common Stock | · | · | $0 | · | · | · | |
| Retained Earnings | $-583M | $-399M | $-290M | $-194M | $-138M | $-45M | |
| AOCI | $1M | $819.0K | $343.0K | $627.0K | $1M | $284.0K | |
| Stockholders' Equity | $332M | $241M | $78M | $151M | $152M | $76M | |
| Liabilities + Equity | $440M | $302M | $125M | $170M | $164M | $82M | |
| Shares Outstanding | 98,776,265 | 75,100,763 | 41,101,303 | 37,979,136 | 28,126,414 | · |
Cash Flow 9
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Deferred Tax | · | · | · | · | $-1M | · | |
| Amort. of Intangibles | $0 | $527.0K | $3M | $3M | $3M | $0 | |
| Operating Cash Flow | $-132M | $-79M | $-64M | $-50M | $-46M | $-24M | |
| Investing Cash Flow | $-152M | $0 | · | · | $-297.0K | · | |
| Stock Issued | $0 | $984.0K | $8M | $42M | $82M | $72M | |
| Net Stock Activity | $0 | $984.0K | $8M | $42M | $82M | · | |
| Financing Cash Flow | $267M | $253M | $22M | $59M | $99M | $97M | |
| Net Change in Cash | $-16M | $174M | $-42M | $9M | $53M | $73M | |
| Taxes Paid | $0 | · | · | · | · | · |
Profitability 7
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | -2012.6% | -4436.9% | 26143.2% | · | |
| Net Margin | · | · | -2052.6% | -3799.1% | 25915.3% | · | |
| Pretax Margin | · | · | -2052.6% | -3799.1% | 26237.6% | · | |
| EBITDA Margin | · | · | -2012.6% | -4436.9% | 26143.2% | · | |
| ROA | -49.5% | -50.9% | -65.0% | -34.0% | -75.8% | · | |
| ROE | -71.0% | -43.2% | -110.0% | -37.3% | -58.9% | · | |
| ROIC | -44.6% | · | · | · | -61.1% | · |
Liquidity & Solvency 5
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 6.3 | 7.2 | 3.2 | 8.2 | 13.2 | · | |
| Quick Ratio | 6.2 | 7.0 | 3.1 | 7.9 | 12.8 | · | |
| Debt / Equity | 0.1 | 0.1 | 0.2 | · | · | · | |
| LT Debt / Equity | 0.1 | 0.1 | 0.2 | · | · | · | |
| Interest Coverage | -30.3 | -45.5 | · | · | · | · |
Efficiency 1
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | 0.0 | 0.0 | -0.0 | · |
Growth Rates 1
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | 212.0% | · | · | · |
Valuation (TTM) 12
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue TTM | $4M | $4M | $5M | $1M | $-359.0K | · | |
| Net Income TTM | $-184M | $-109M | $-96M | $-57M | $-93M | · | |
| Market Cap | $1.32B | $523M | · | · | · | · | |
| Enterprise Value | $952M | $271M | · | · | · | · | |
| P/E | -6.5 | -4.5 | · | · | · | · | |
| P/S | 321.2 | 126.9 | · | · | · | · | |
| P/B | 4.0 | 2.2 | · | · | · | · | |
| P / Tangible Book | 4.2 | 2.4 | · | · | · | · | |
| P / Cash Flow | -10.1 | -6.6 | · | · | · | · | |
| EV / EBITDA | -5.7 | -2.6 | · | · | · | · | |
| EV / Revenue | 231.1 | 65.8 | · | · | · | · | |
| Earnings Yield | -15.4% | -22.1% | · | · | · | · |
Income Statement 14
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $49M | $41M | $34M | $31M | $30M | $23M | $22M | $17M | $15M | $12M | $12M | $13M | $15M | $13M | $9M | $8M | |
| SG&A Expense | $26M | $18M | $14M | $15M | $11M | $9M | $11M | $8M | $10M | $10M | $11M | $8M | $14M | $8M | $5M | $9M | |
| Operating Expenses | $75M | $59M | $48M | $46M | $41M | $32M | $32M | $25M | $24M | $22M | $22M | $22M | $29M | $21M | $14M | $17M | |
| Operating Income | $-75M | $-59M | $-48M | $-46M | $-41M | $-32M | $-32M | $-25M | $-24M | $-22M | $-22M | $-22M | $-29M | $-21M | $-14M | $-17M | |
| Interest Expense | $1M | $1M | $1M | $1M | $2M | $602.0K | $656.0K | $727.0K | $466.0K | $434.0K | $439.0K | $328.0K | $77.0K | $76.0K | · | · | |
| Other Non-op | $-84M | $-18M | $-3M | $-22M | $-2M | $9M | $-2M | $11M | $19M | $-32M | $-2M | $4M | $54.0K | $-4M | $9M | $498.0K | |
| Pretax Income | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $-5M | $-16M | |
| Income Tax | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| Net Income | $-159M | $-77M | $-50M | $-67M | $-43M | $-23M | $-35M | $-14M | $-6M | $-54M | $-24M | $-18M | $-29M | $-25M | $-5M | $-16M | |
| EPS (Basic) | $-1.44 | $-0.71 | $-0.51 | $-0.78 | $-0.50 | $-0.27 | $-0.14 | $-0.18 | $-0.08 | $-1.14 | $-0.58 | $-0.45 | $-0.76 | $-0.65 | $-0.02 | $-0.56 | |
| EPS (Diluted) | $-1.44 | $-0.71 | $-0.43 | $-0.78 | $-0.50 | $-0.35 | $0.13 | $-0.27 | $-0.26 | $-1.14 | $-0.58 | $-0.45 | $-0.76 | $-0.65 | $-0.02 | $-0.56 | |
| Shares (Basic) | 110,684,720 | 108,790,941 | -166,973,440 | 85,885,516 | 85,347,677 | 85,067,855 | -127,221,454 | 77,909,441 | 71,912,323 | 47,860,757 | -77,216,232 | 39,720,007 | 38,576,394 | 38,077,251 | -54,828,395 | 29,296,333 | |
| Shares (Diluted) | 110,684,720 | 108,790,941 | -168,997,046 | 85,885,516 | 85,347,677 | 87,091,461 | -132,942,479 | 80,238,688 | 75,304,101 | 47,860,757 | -77,216,232 | 39,720,007 | 38,576,394 | 38,077,251 | -54,828,395 | 29,296,333 | |
| EBITDA | $-75M | $-59M | · | $-46M | $-41M | $-32M | · | $-25M | $-24M | $-22M | · | $-22M | $-29M | $-21M | · | $-17M |
Balance Sheet 20
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $655M | $263M | $258M | $20M | $33M | $83M | $274M | $295M | $243M | $252M | $100M | $118M | $117M | $129M | $142M | $155M | |
| Short-term Investments | $429M | $111M | $154M | $189M | $150M | $130M | $0 | · | · | · | · | · | · | · | · | · | |
| Prepaid Expense | $8M | $7M | $8M | $7M | $6M | $9M | $8M | $4M | $5M | $3M | $4M | $2M | $3M | $3M | $4M | $2M | |
| Current Assets | $1.09B | $381M | $419M | $216M | $189M | $222M | $282M | $299M | $248M | $255M | $104M | $120M | $120M | $132M | $146M | $157M | |
| Goodwill | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | $20M | |
| Intangibles | · | · | · | · | · | · | · | · | · | · | $527.0K | $1M | $2M | $3M | $4M | $4M | |
| Other Non-current Assets | $880.0K | $812.0K | $862.0K | $1M | $1M | $606.0K | $613.0K | $493.0K | $534.0K | $144.0K | $224.0K | $229.0K | $268.0K | $300.0K | $331.0K | · | |
| Total Assets | $1.11B | $401M | $440M | $237M | $265M | $275M | $302M | $320M | $268M | $276M | $125M | $142M | $142M | $156M | $170M | $181M | |
| Accounts Payable | $7M | $7M | $5M | $8M | $4M | $2M | $2M | $2M | $3M | $8M | $4M | $8M | $9M | $2M | $2M | $824.0K | |
| Accrued Liabilities | $37M | $25M | $20M | $19M | $15M | $11M | $13M | $9M | $8M | $10M | $12M | $10M | $10M | $7M | $6M | $7M | |
| Current Liabilities | $157M | $81M | $67M | $65M | $38M | $30M | $39M | $33M | $42M | $65M | $32M | $31M | $35M | $24M | $18M | $26M | |
| Other Non-current Liabilities | $549.0K | $559.0K | $496.0K | $519.0K | $543.0K | · | · | · | · | $15.0K | $32.0K | $349.0K | $992.0K | $1M | $1M | $1M | |
| Total Liabilities | $194M | $122M | $108M | $106M | $80M | $53M | $61M | $58M | $66M | $79M | $46M | $46M | $36M | $25M | $19M | $27M | |
| Total Debt | $36M | $41M | · | $40M | $41M | $22M | · | $24M | $24M | $14M | · | $14M | · | · | · | · | |
| Common Stock | · | · | · | · | · | · | · | $0 | $0 | · | $0 | · | · | · | · | · | |
| Retained Earnings | $-819M | $-660M | $-583M | $-532M | $-465M | $-422M | $-399M | $-364M | $-350M | $-345M | $-290M | $-266M | $-248M | $-219M | $-194M | $-190M | |
| AOCI | $417.0K | $824.0K | $1M | $1M | $807.0K | $802.0K | $819.0K | $821.0K | $833.0K | $836.0K | $343.0K | $777.0K | $362.0K | $641.0K | $627.0K | $743.0K | |
| Stockholders' Equity | $919M | $279M | $332M | $131M | $185M | $223M | $241M | $262M | $202M | $196M | $78M | $96M | $106M | $130M | $151M | $154M | |
| Liabilities + Equity | $1.11B | $401M | $440M | $237M | $265M | $275M | $302M | $320M | $268M | $276M | $125M | $142M | $142M | $156M | $170M | $181M | |
| Shares Outstanding | 134,365,950 | 104,044,508 | 98,776,265 | 76,774,057 | 75,803,251 | 75,511,375 | 75,100,763 | 81,590,491 | 72,075,076 | 71,163,720 | 41,101,303 | 40,094,708 | 38,807,159 | 38,290,111 | 37,979,136 | 37,541,115 |
Cash Flow 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amort. of Intangibles | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $527.0K | $771.0K | $800.0K | $800.0K | $791.0K | $800.0K | $800.0K | |
| Operating Cash Flow | $-53M | $-43M | $-43M | $-30M | $-30M | $-29M | $-25M | $-17M | $-20M | $-17M | $-21M | $-17M | $-14M | $-13M | $-13M | $-9M | |
| Investing Cash Flow | $-317M | $42M | $35M | $15M | $-40M | $-162M | $0 | $0 | $0 | $0 | · | · | · | · | · | · | |
| Stock Issued | · | · | $0 | $0 | · | · | $0 | $0 | · | · | $3M | $3M | $1M | $583.0K | $730.0K | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | · | · | $583.0K | · | · | |
| Financing Cash Flow | $762M | $5M | $246M | $749.0K | $20M | $1M | $4M | $69M | $11M | $169M | $3M | $17M | $1M | $583.0K | $416.0K | $58M | |
| Net Change in Cash | $393M | $5M | $238M | $-13M | $-49M | $-191M | $-22M | $52M | $-9M | $153M | $-18M | $804.0K | $-13M | $-13M | $-12M | $49M |
Profitability 7
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | · | · | · | -1858.6% | -2226.1% | -1624.8% | · | -4717.5% | |
| Net Margin | · | · | · | · | · | · | · | · | · | · | · | -1541.1% | -2222.0% | -1932.6% | · | -4579.2% | |
| Pretax Margin | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -4579.2% | |
| EBITDA Margin | · | · | · | · | · | · | · | · | · | · | · | -1858.6% | -2226.1% | -1624.8% | · | -4717.5% | |
| ROA | -23.1% | -22.8% | · | -24.2% | -16.0% | -8.5% | · | -5.9% | -2.9% | -25.2% | · | -11.1% | -21.1% | -16.3% | · | -18.2% | |
| ROE | -28.8% | -30.7% | · | -34.2% | -22.1% | -11.2% | · | -7.6% | -3.8% | -33.3% | · | -14.4% | -25.3% | -18.6% | · | -21.5% | |
| ROIC | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -11.1% |
Liquidity & Solvency 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 6.9 | 4.7 | · | 3.3 | 5.0 | 7.3 | · | 9.0 | 5.9 | 3.9 | · | 3.9 | 3.4 | 5.5 | · | 6.0 | |
| Quick Ratio | 6.9 | 4.6 | · | 3.2 | 4.8 | 7.0 | · | 8.9 | 5.8 | 3.9 | · | 3.8 | 3.3 | 5.4 | · | 5.9 | |
| Debt / Equity | 0.0 | 0.1 | · | 0.3 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | · | · | · | · | |
| LT Debt / Equity | 0.0 | 0.1 | · | 0.3 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | · | · | · | · | |
| Interest Coverage | -60.9 | -47.6 | · | -35.8 | -17.5 | -53.4 | · | -34.1 | -52.5 | -51.2 | · | · | · | · | · | · |
Efficiency 1
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | · | · | · | · | · | 0.0 | 0.0 | 0.0 | · | 0.0 |
Valuation (TTM) 12
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $4M | $4M | · | $4M | $4M | $4M | · | $4M | $4M | $4M | · | $4M | $3M | $2M | · | $351.0K | |
| Net Income TTM | $-346M | $-210M | · | $-147M | $-86M | $-97M | · | $-92M | $-107M | $-126M | · | $-88M | $-87M | $-77M | · | $-69M | |
| Market Cap | $6.32B | $1.97B | · | $905M | $492M | $442M | · | $464M | $520M | $669M | · | · | · | · | · | · | |
| Enterprise Value | $5.27B | $1.63B | · | $736M | $350M | $251M | · | $193M | $301M | $431M | · | · | · | · | · | · | |
| P/E | -13.7 | -8.1 | · | -6.2 | -4.7 | -2.9 | · | -2.7 | -2.8 | -3.1 | · | · | · | · | · | · | |
| P/S | 1534.9 | 477.5 | · | 219.8 | 119.5 | 107.3 | · | 112.7 | 126.2 | 162.4 | · | · | · | · | · | · | |
| P/B | 6.9 | 7.1 | · | 6.9 | 2.7 | 2.0 | · | 1.8 | 2.6 | 3.4 | · | · | · | · | · | · | |
| P / Tangible Book | 7.0 | 7.6 | · | 8.2 | 3.0 | 2.2 | · | 1.9 | 2.9 | 3.8 | · | · | · | · | · | · | |
| P / Cash Flow | · | -46.1 | · | · | · | -15.0 | · | · | · | -40.3 | · | · | · | · | · | · | |
| EV / EBITDA | -70.2 | -27.6 | · | -16.1 | -8.6 | -7.8 | · | -7.8 | -12.3 | -19.4 | · | · | · | · | · | · | |
| EV / Revenue | 1280.5 | 396.7 | · | 178.8 | 85.0 | 61.0 | · | 46.9 | 73.0 | 104.6 | · | · | · | · | · | · | |
| Earnings Yield | -7.3% | -12.4% | · | -16.1% | -21.3% | -34.5% | · | -37.3% | -36.2% | -31.9% | · | · | · | · | · | · |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Operating Margin % | — | — | -2012.6% | -4436.9% | 26143.2% |
| Net Income | $-184M | $-109M | $-96M | $-57M | $-93M |
| Diluted EPS | $-2.06 | $-1.54 | $-2.44 | $-1.84 | $-3.40 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Debt / Equity | 0.1 | 0.1 | 0.2 | — | — |
| Current Ratio | 6.3 | 7.2 | 3.2 | 8.2 | 13.2 |
| Quick Ratio | 6.2 | 7.0 | 3.1 | 7.9 | 12.8 |
My Metrics Your personal watchlist — selected rows from Full Fundamentals
Pick the metrics that matter to you — click the ➕ next to any row in Full Fundamentals above.
Your selection is saved and follows you across all tickers.
Institutional owners (13F) 387 filers · $4.0B total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 167 | 28 | 108 | 69 | — |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair. Change vs prior quarter not shown: filer coverage differs too much between these two quarters for a reliable comparison.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | $338,165,292 | 7,188,888 | 8.35% | Shares |
| Driehaus Capital Management LLC | $322,001,783 | 6,845,276 | 7.95% | Shares |
| Capital World Investors | $252,497,690 | 5,367,723 | 6.24% | Shares |
| FMR LLC | $188,434,384 | 4,005,833 | 4.65% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $148,941,987 | 3,165,629 | 3.68% | Shares |
| STATE STREET CORP | $144,195,946 | 3,065,390 | 3.56% | Shares |
| Capital International Investors | $139,398,806 | 2,963,410 | 3.44% | Shares |
| Octagon Capital Advisors LP | $138,768,000 | 2,950,000 | 3.43% | Shares |
| Deep Track Capital, LP | $129,360,000 | 2,750,000 | 3.20% | Shares |
| WELLINGTON MANAGEMENT GROUP LLP | $104,294,124 | 2,217,137 | 2.58% | Shares |
| Commodore Capital LP | $94,080,000 | 2,000,000 | 2.32% | Shares |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $77,541,959 | 1,648,426 | 1.92% | Shares |
| RA CAPITAL MANAGEMENT, L.P. | $70,560,000 | 1,500,000 | 1.74% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $69,922,796 | 1,486,454 | 1.73% | Shares |
| Siren, L.L.C. | $66,772,951 | 1,419,493 | 1.65% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $65,216,256 | 1,386,400 | 1.61% | Call option |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $50,971,415 | 1,083,576 | 1.26% | Shares |
| GOLDMAN SACHS GROUP INC | $49,226,937 | 1,046,491 | 1.22% | Shares |
| Woodline Partners LP | $47,211,273 | 1,003,641 | 1.17% | Shares |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $47,040,000 | 1,000,000 | 1.16% | Shares |
| Boxer Capital Management, LLC | $46,969,440 | 998,500 | 1.16% | Shares |
| CITADEL ADVISORS LLC | $43,623,579 | 927,372 | 1.08% | Shares |
| TWO SIGMA INVESTMENTS, LP | $43,362,319 | 921,818 | 1.07% | Shares |
| Balyasny Asset Management L.P. | $42,217,365 | 897,478 | 1.04% | Shares |
| AMERIPRISE FINANCIAL INC | $41,156,144 | 874,918 | 1.02% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $38,934,679 | 827,693 | 0.96% | Shares |
| Holocene Advisors, LP | $37,470,841 | 796,574 | 0.93% | Shares |
| AWM Investment Company, Inc. | $36,916,992 | 784,800 | 0.91% | Shares |
| Polar Capital Holdings Plc | $36,561,981 | 777,253 | 0.90% | Shares |
| ALLIANCEBERNSTEIN L.P. | $34,082,124 | 1,803,287 | 0.84% | Shares |
| EVENTIDE ASSET MANAGEMENT, LLC | $33,398,400 | 710,000 | 0.82% | Shares |
| Qube Research & Technologies Ltd | $32,123,663 | 682,901 | 0.79% | Shares |
| NEUBERGER BERMAN GROUP LLC | $29,068,697 | 617,957 | 0.72% | Shares |
| Candriam S.C.A. | $28,874,744 | 614,425 | 0.71% | Shares |
| ArrowMark Colorado Holdings LLC | $26,533,806 | 564,069 | 0.66% | Shares |
| Catalio Capital Management, LP | $26,468,091 | 562,672 | 0.65% | Shares |
| Blackstone Inc. | $26,418,228 | 561,612 | 0.65% | Shares |
| Integral Health Asset Management, LLC | $25,872,000 | 550,000 | 0.64% | Shares |
| BAMCO INC /NY/ | $24,465,880 | 520,108 | 0.60% | Shares |
| FRANKLIN RESOURCES INC | $22,871,742 | 486,219 | 0.56% | Shares |
| Point72 Asset Management, L.P. | $22,766,419 | 483,980 | 0.56% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $22,155,840 | 471,000 | 0.55% | Put option |
| Ensign Peak Advisors, Inc | $21,925,626 | 466,106 | 0.54% | Shares |
| GREAT POINT PARTNERS LLC | $19,992,000 | 425,000 | 0.49% | Shares |
| JANE STREET GROUP, LLC | $19,940,256 | 423,900 | 0.49% | Call option |
| RTW INVESTMENTS, LP | $18,816,000 | 400,000 | 0.46% | Shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | $18,816,000 | 400,000 | 0.46% | Shares |
| Cormorant Asset Management, LP | $18,816,000 | 400,000 | 0.46% | Shares |
| Ally Bridge Group (NY) LLC | $18,816,000 | 400,000 | 0.46% | Call option |
| ASSETMARK, INC | $18,653,336 | 396,542 | 0.46% | Shares |
| MARSHALL WACE, LLP | $18,196,013 | 386,820 | 0.45% | Shares |
| Caption Management, LLC | $17,503,584 | 372,100 | 0.43% | Call option |
| ORBIMED ADVISORS LLC | $17,188,416 | 365,400 | 0.42% | Shares |
| JANE STREET GROUP, LLC | $15,415,008 | 327,700 | 0.38% | Put option |
| SILVERBACK ASSET MANAGEMENT LLC | $13,848,576 | 294,400 | 0.34% | Call option |
| CITADEL ADVISORS LLC | $13,547,520 | 288,000 | 0.33% | Call option |
| Tetragon Partners GP Ltd | $13,500,010 | 286,990 | 0.33% | Shares |
| CITADEL ADVISORS LLC | $13,382,880 | 284,500 | 0.33% | Put option |
| MILLENNIUM MANAGEMENT LLC | $12,516,215 | 266,076 | 0.31% | Shares |
| Sofinnova Investments, Inc. | $12,037,677 | 255,903 | 0.30% | Shares |
| PFM Health Sciences, LP | $11,713,901 | 249,020 | 0.29% | Shares |
| HighVista Strategies LLC | $11,425,263 | 242,884 | 0.28% | Shares |
| Trexquant Investment LP | $10,969,681 | 233,199 | 0.27% | Shares |
| SEVEN GRAND MANAGERS, LLC | $10,584,000 | 225,000 | 0.26% | Shares |
| Swiss National Bank | $10,405,248 | 221,200 | 0.26% | Shares |
| Eversept Partners, LP | $10,216,382 | 217,185 | 0.25% | Shares |
| TD Asset Management Inc | $9,852,998 | 209,460 | 0.24% | Shares |
| ROYCE & ASSOCIATES LP | $9,810,239 | 208,551 | 0.24% | Shares |
| SEB Asset Management AB | $9,796,249 | 208,254 | 0.24% | Shares |
| SUPERSTRING CAPITAL MANAGEMENT LP | $8,856,785 | 188,282 | 0.22% | Shares |
| EMERALD ADVISERS, LLC | $8,408,447 | 178,751 | 0.21% | Shares |
| Aberdeen Group plc | $8,232,000 | 175,000 | 0.20% | Shares |
| Tri Locum Partners LP | $7,667,332 | 162,996 | 0.19% | Shares |
| RHUMBLINE ADVISERS | $7,436,824 | 158,096 | 0.18% | Shares |
| Bank of New York Mellon Corp | $7,078,203 | 150,472 | 0.17% | Shares |
| Seven Fleet Capital Management LP | $6,992,355 | 148,647 | 0.17% | Shares |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $6,885,151 | 146,368 | 0.17% | Shares |
| Brevan Howard Capital Management LP | $6,750,146 | 143,498 | 0.17% | Shares |
| Rock Springs Capital Management LP | $6,735,516 | 143,187 | 0.17% | Shares |
| SummitTX Capital, L.P. | $6,702,683 | 142,489 | 0.17% | Shares |
| STEMPOINT CAPITAL LP | $6,450,313 | 137,124 | 0.16% | Shares |
| BIT Capital GmbH | $6,027,282 | 128,131 | 0.15% | Shares |
| FRED ALGER MANAGEMENT, LLC | $5,892,042 | 125,256 | 0.15% | Shares |
| BlackRock, Inc. | $5,861,090 | 124,598 | 0.14% | Shares |
| BANK OF AMERICA CORP /DE/ | $5,747,818 | 122,190 | 0.14% | Shares |
| AdvisorShares Investments LLC | $5,709,762 | 121,381 | 0.14% | Shares |
| EMERALD MUTUAL FUND ADVISERS TRUST | $5,703,553 | 121,249 | 0.14% | Shares |
| Informed Momentum Co LLC | $5,688,453 | 120,928 | 0.14% | Shares |
| Schonfeld Strategic Advisors LLC | $5,626,452 | 119,610 | 0.14% | Shares |
| ALPS ADVISORS INC | $5,192,652 | 110,388 | 0.13% | Shares |
| MILLENNIUM MANAGEMENT LLC | $5,174,400 | 110,000 | 0.13% | Put option |
| Russell Investments Group, Ltd. | $4,987,933 | 106,036 | 0.12% | Shares |
| Data Collective IV GP, LLC | $4,720,464 | 100,350 | 0.12% | Shares |
| Burkehill Global Management, LP | $4,704,000 | 100,000 | 0.12% | Shares |
| BNP PARIBAS FINANCIAL MARKETS | $4,539,830 | 96,510 | 0.11% | Shares |
| KEYSTONE INVESTORS PTE LTD | $4,473,504 | 95,100 | 0.11% | Shares |
| SIG BROKERAGE, LP | $4,384,128 | 93,200 | 0.11% | Call option |
| Pier Capital, LLC | $4,167,650 | 88,598 | 0.10% | Shares |
| LPL Financial LLC | $4,051,837 | 86,136 | 0.10% | Shares |
| Squadron Capital Management LLC | $3,998,400 | 85,000 | 0.10% | Shares |
Company insiders 16 insiders · 4 officers · 7 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Schond L. Greenway | Chief Financial Officer | March 25, 2024 F | 211,057 | 0 | 0 | $0 |
| Miri Halperin Wernli | Executive President | Aug. 21, 2024 M | 202,405 | 0 | 0 | $0 |
| Carrie Liao | Chief Accounting Officer | March 25, 2025 S | 144,923 | 0 | 0 | $0 |
| Cynthia W. Hu | Chief Legal Officer&Secretary | March 24, 2022 A | 1,200,000 | 0 | 0 | $0 |
| Roger Adsett | Director | June 11, 2026 A | 3,555 | 0 | 0 | $0 |
| Roger Crystal | Director | June 11, 2026 A | 24,289 | 0 | 0 | $0 |
| Suzanne Louise Bruhn | Director | June 11, 2026 A | 24,289 | 0 | 0 | $0 |
| Andreas Krebs | Director | June 11, 2026 A | 19,773 | 0 | 0 | $0 |
| Carol A Vallone | Director | June 11, 2026 A | 21,210 | 0 | 0 | $0 |
| David W Gryska | Director | June 11, 2026 A | 19,900 | 0 | 0 | $0 |
| Brigid Makes | Director | June 1, 2022 A | 158,706 | 0 | 0 | $0 |
| Dan Karlin | — | Aug. 12, 2026 A | 603,282 | 0 | 4 | $-748,876 |
| Robert Barrow | — | Aug. 12, 2026 A | 1,473,246 | 0 | 4 | $-2,357,666 |
| Matthew T. Wiley | — | Aug. 12, 2026 A | 237,133 | 0 | 1 | $-129,101 |
| Brandi Roberts | — | Aug. 12, 2026 A | 271,987 | 0 | 1 | $-135,675 |
| Mark Sullivan | — | Aug. 12, 2026 A | 383,071 | 0 | 4 | $-1,041,881 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 34 ETFs
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| PILL · Direxion Shares ETF Trust | 1.57% | 9,260 NS | April 30, 2026 | N-PORT |
| BBC · ETFis Series Trust I | 1.29% | 21,993 NS | April 30, 2026 | N-PORT |
| GSC · Goldman Sachs ETF Trust | 0.68% | 70,926 NS | May 31, 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 0.51% | 4,214 NS | May 31, 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0.44% | 9,471 NS | May 31, 2026 | N-PORT |
| NUSC · Nushares ETF Trust | 0.14% | 83,684 NS | April 30, 2026 | N-PORT |
| BIB · ProShares Trust | 0.12% | 3,685 NS | May 31, 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0.08% | 31,411 NS | May 31, 2026 | N-PORT |
| RSSL · Global X Funds | 0.07% | 42,629 NS | April 30, 2026 | N-PORT |
| ITWO · ProShares Trust | 0.06% | 4,634 NS | May 31, 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0.05% | 473,075 NS | May 31, 2026 | N-PORT |
| UWM · ProShares Trust | 0.04% | 3,624 NS | May 31, 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0.03% | 37,154 NS | April 30, 2026 | N-PORT |
| URTY · ProShares Trust | 0.03% | 3,665 NS | May 31, 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0.01% | 3,505 NS | May 31, 2026 | N-PORT |
| HDG · ProShares Trust | 0.01% | 92 NS | May 31, 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0.01% | 40,894 NS | May 31, 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0.00% | 55,178 NS | May 31, 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | July 15, 2026 | Daily |
| VFMO · VANGUARD WELLINGTON FUND | — | — | July 30, 2026 | Daily |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | July 15, 2026 | Daily |
| ITOT · iShares Trust | — | — | Aug. 3, 2026 | Daily |
| IWV · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IWO · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IWM · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IBB · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| IHE · iShares Trust | — | — | Aug. 18, 2026 | Daily |
| PRFZ · Invesco Exchange-Traded Fund Trust | — | — | July 13, 2026 | Daily |
| VHT · VANGUARD WORLD FUND | — | — | July 20, 2026 | Daily |
| ESML · iShares Trust | — | — | Aug. 14, 2026 | Daily |
| WSML · iShares Trust | — | — | July 20, 2026 | Daily |
| IBBQ · Invesco Exchange-Traded Fund Trust … | — | — | July 20, 2026 | Daily |