MANE Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

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Price $116.76
Market Cap (MRQ) $4.88B
EPS $-111.91
ROE 82.6%
52W Range $32–$131

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10-Year Performance Revenue, net income, margins and EPS trends

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EPS$-111.91
2024-12-31 → 2025-12-31
Free Cash Flow$-72M
2025-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend MANE 5Y avg Peer Median Verdict
P/B (MRQ) 6.0 · 6.5 Undervalued

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

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Avg Surprise -42.8%
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 $-0.58 $-0.66 12.2%
March 31, 2026 $-1.32 $-0.67 -97.7%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

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Income Statement 14
Metric Trend 20252024
R&D Expense $62M$23M
SG&A Expense $10M$3M
Operating Expenses $72M$27M
Operating Income $-72M$-27M
Interest Income $2M$481.0K
Other Non-op $2M$290.0K
Pretax Income $-70M$-26M
Income Tax $0$0
Net Income $-70M$-26M
EPS (Basic) $-111.91$-37.05
EPS (Diluted) $-111.91$-37.05
Shares (Basic) 744,991736,933
Shares (Diluted) 744,991736,933
EBITDA $-72M·
Balance Sheet 18
Metric Trend 20252024
Cash & Equivalents $22M$53M
Prepaid Expense $11M$2M
Other Current Assets $307.0K$38.0K
Current Assets $152M$56M
PP&E (Net) $22.0K$0
Total Assets $153M$56M
Accounts Payable $2M$2M
Accrued Liabilities $7M$2M
Current Liabilities $9M$5M
Capital Leases $4.0K$0
Total Liabilities $9M$5M
Common Stock $1.0K$1.0K
Paid-in Capital $2M$750.0K
Retained Earnings $-123M$-49M
AOCI $60.0K$0
Stockholders' Equity $-121M$-48M
Liabilities + Equity $153M$56M
Shares Outstanding 749,760736,933
Cash Flow 8
Metric Trend 20252024
Stock-based Comp $1M$250.0K
Operating Cash Flow $-72M$-24M
CapEx $24.0K$0
Investing Cash Flow $-119M$0
Financing Cash Flow $159M$60M
Net Change in Cash $-31M$37M
Taxes Paid $0$0
Free Cash Flow $-72M·
Profitability 3
Metric Trend 20252024
ROA -67.2%·
ROE 82.6%·
ROIC 59.8%·
Liquidity & Solvency 2
Metric Trend 20252024
Current Ratio 16.7·
Quick Ratio 2.4·
Per Share 4
Metric Trend 20252024
Book Value / Share $-161.40·
Cash Flow / Share $-96.11·
Cash / Share $29.03·
EPS (TTM) $-111.91·
Valuation (TTM) 1
Metric Trend 20252024
Net Income TTM $-70M·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-31
Net Income $-70M $-26M
Diluted EPS $-111.91 $-37.05

Institutional owners (13F) 162 filers · $4.2B total · As of Sept. 30, 2026

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Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 162
Value held $4.2B
New positions 95
Exited positions 14
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
95 14 41 18 ·

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair. Change vs prior quarter not shown: filer coverage differs too much between these two quarters for a reliable comparison.

Institution Value Shares % of tracked 13F Type
MONTANOVA CAPITAL, LLC $512,533,172 4,168,970 12.31% Shares
FMR LLC $394,020,365 3,204,981 9.46% Shares
SR One Capital Management, LP $295,285,652 2,401,868 7.09% Shares
Deep Track Capital, LP $245,880,000 2,000,000 5.90% Shares
CITADEL ADVISORS LLC $230,853,659 1,877,775 5.54% Shares
Siren, L.L.C. $203,511,680 1,655,374 4.89% Shares
BlackRock, Inc. $195,940,665 1,593,791 4.70% Shares
VIKING GLOBAL INVESTORS LP $191,970,072 1,561,494 4.61% Shares
JPMORGAN CHASE & CO $144,239,451 1,165,584 3.46% Shares
Aberdeen Group plc $134,821,167 1,096,642 3.24% Shares
D. E. Shaw & Co., Inc. $124,617,270 1,013,643 2.99% Shares
VANGUARD CAPITAL MANAGEMENT LLC $106,860,923 869,212 2.57% Shares
MAVERICK CAPITAL LTD $97,120,141 789,980 2.33% Shares
JENNISON ASSOCIATES LLC $92,042,475 748,678 2.21% Shares
INFINITUM ASSET MANAGEMENT, LLC $89,887,458 731,149 2.16% Shares
UBS Group AG $82,459,177 670,727 1.98% Shares
MARSHALL WACE, LLP $71,988,746 585,560 1.73% Shares
ADAGE CAPITAL PARTNERS GP, L.L.C. $67,580,856 549,706 1.62% Shares
STATE STREET CORP $66,924,725 544,369 1.61% Shares
GEODE CAPITAL MANAGEMENT, LLC $62,477,233 508,067 1.50% Shares
Woodline Partners LP $61,665,475 501,590 1.48% Shares
Bank of New York Mellon Corp $42,609,106 346,585 1.02% Shares
STIFEL FINANCIAL CORP $36,158,744 294,117 0.87% Shares
EMERALD ADVISERS, LLC $35,452,208 288,370 0.85% Shares
FRONTIER CAPITAL MANAGEMENT CO LLC $31,334,455 254,876 0.75% Shares
BAMCO INC /NY/ $28,224,688 229,581 0.68% Shares
EMERALD MUTUAL FUND ADVISERS TRUST $25,808,057 209,924 0.62% Shares
Logos Global Management LP $22,129,200 180,000 0.53% Shares
NORTHERN TRUST CORP $21,897,088 178,112 0.53% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $21,170,391 172,201 0.51% Shares
Balyasny Asset Management L.P. $20,768,746 168,934 0.50% Shares
AMERIPRISE FINANCIAL INC $18,509,808 150,560 0.44% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $18,324,699 149,054 0.44% Shares
Sofinnova Investments, Inc. $18,317,199 148,993 0.44% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $18,175,573 147,841 0.44% Shares
Kalehua Capital Management LLC $17,911,743 145,695 0.43% Shares
VANGUARD FIDUCIARY TRUST CO $17,361,956 141,223 0.42% Shares
Ensign Peak Advisors, Inc $15,720,092 127,868 0.38% Shares
SEVEN GRAND MANAGERS, LLC $15,367,500 125,000 0.37% Shares
Affinity Asset Advisors, LLC $12,294,000 100,000 0.30% Shares
MASTERS CAPITAL MANAGEMENT LLC $12,294,000 100,000 0.30% Shares
MYDA Advisors LLC $12,294,000 100,000 0.30% Shares
FRANKLIN RESOURCES INC $11,809,371 96,058 0.28% Shares
SILVERARC CAPITAL MANAGEMENT, LLC $11,679,300 95,000 0.28% Shares
GILDER GAGNON HOWE & CO LLC $11,662,580 94,864 0.28% Shares
RENAISSANCE TECHNOLOGIES LLC $10,062,885 81,852 0.24% Shares
Seven Fleet Capital Management LP $9,835,200 80,000 0.24% Shares
MORGAN STANLEY $9,328,297 75,876 0.22% Shares
DV EQUITIES, LLC $8,605,800 70,000 0.21% Shares
WELLINGTON MANAGEMENT GROUP LLP $8,425,201 68,531 0.20% Shares

Show all 162 institutional owners →

Activists & 5%+ owners 5 positions

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Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Aaron Cowen, Averill Madison Master Fund, Ltd., Averill Master Fund, Ltd., Montanova Capital, LLC Aug. 21, 2026 8.80% Amendment · SEC
SR One Capital Management, LLC, SR One Capital Fund II Aggregator, LP, SR One Capital Partners II, LP, AMZL, LP, SR One Capital SMA Partners, LP, Simeon George ×2 filings Aug. 14, 2026 4.90% Amendment · SEC
Longitude Capital Partners V, LLC, Longitude Venture Partners V, L.P., Longitude 103.8 East Partners, LLC, Longitude 103.8 East, L.P., Patrick G. Enright, Juliet Tammenoms Bakker ×2 filings May 5, 2026 11.30% Amendment · SEC
SUVRETTA CAPITAL MANAGEMENT, LLC, Averill Master Fund, Ltd., Averill Madison Master Fund, Ltd., Aaron Cowen ×2 filings May 5, 2026 9.90% Amendment · SEC
Seven Fleet Master Fund LP, Seven Fleet Capital Management LP, Seven Fleet Capital Management GP LLC, Brian Liu May 5, 2026 0.20% Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 12 insiders · 6 officers · 7 directors

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Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Reid Alexander Waldman Chief Executive Officer Aug. 17, 2026 M 170,824 0 5 $-7,280,712
Dominic Gabriel Carrano Chief Financial Officer Feb. 3, 2026 A · 0 0 $0
David Hollander Chief R&D Officer Sept. 1, 2026 A 9,650 0 0 $0
Timothy August Durso Chief Technical Officer Aug. 17, 2026 M 78,142 0 5 $-4,690,004
Michael V. Greco General Counsel Feb. 3, 2026 A · 0 0 $0
Mark Neumann Chief Commercial Officer Feb. 3, 2026 A · 0 0 $0
John W Childs Director Aug. 12, 2026 S 194,117 2 3 $-711,722
David Matthew Friedman Director Feb. 3, 2026 A · 0 0 $0
Jane M. Grant-Kels Director Feb. 3, 2026 A 2,455 0 0 $0
Katarina Pance Director Feb. 3, 2026 A · 0 0 $0
Vlad Coric Director Feb. 3, 2026 A 319,398 2 0 $1,999,982
Patrick G. Enright Director Feb. 3, 2026 A 2,053,474 2 0 $18,275,000

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 20 ETFs

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Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PILL · Direxion Shares ETF Trust 1.28% 2,526 NS July 31, 2026 N-PORT
BBC · ETFis Series Trust I 0.73% 3,235 NS July 31, 2026 N-PORT
IHE · iShares Trust 0.45% 74,227 SH Sept. 11, 2026 Daily
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.14% 9,302 NS July 31, 2026 N-PORT
VTWG · VANGUARD SCOTTSDALE FUNDS 0.11% 16,071 SH Aug. 19, 2026 Daily
IWO · iShares Trust 0.10% 141,006 SH Sept. 11, 2026 Daily
VTWO · VANGUARD SCOTTSDALE FUNDS 0.08% 125,297 SH Aug. 19, 2026 Daily
RSSL · Global X Funds 0.07% 10,423 NS July 31, 2026 N-PORT
IWM · iShares Trust 0.07% 557,089 SH Sept. 11, 2026 Daily
VTWV · VANGUARD SCOTTSDALE FUNDS 0.05% 5,895 SH Aug. 19, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.03% 230,728 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.02% 7,340 NS July 31, 2026 N-PORT
WSML · iShares Trust 0.02% 1,052 SH Sept. 11, 2026 Daily
OMFS · Invesco Exchange-Traded Self-Indexe… 0.01% 161 SH Oct. 1, 2026 Daily
ITOT · iShares Trust 0.00% 28,710 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.00% 5,828 SH Sept. 11, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.00% 618,584 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.00% 1,791 SH Aug. 19, 2026 Daily
IWN · iShares Trust · 64,296 SH Sept. 11, 2026 Daily
ISCB · iShares Trust · 1,540 SH Sept. 11, 2026 Daily

MANE Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

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rating · 13 analysts BUY
Median target $167.00 +43.0%
5 38.5% Strong Buy
7 53.8% Buy
1 7.7% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

6 analysts · 2026-09-27

Mean target $163.50 +40.0%

← Below all targets Current price $116.76
Low$135.00 Mean$163.50 High$182.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

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FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
MANE · · · · 82.6% ·
BLTE $6.29B -69.2 · · -16.9% ·
AMRX · 57.3 8.1% 2.4% -80.0% 36.9%
LGND $3.74B 30.8 60.4% 46.4% 13.5% ·
DFTX $1.32B -6.5 212.0% · -71.0% ·
EWTX $2.64B -15.2 · · -30.2% ·
INDV · 21.9 4.3% 17.0% -118.3% 80.2%
OGN $1.87B 10.0 -2.9% 3.0% 25.2% 53.3%
AMLX $1.33B -7.9 -77.1% · -61.2% ·
TARS $3.48B -51.5 146.7% -14.7% -19.7% ·

Latest News Recent headlines mentioning this company

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My Metrics Your personal watchlist — selected rows from Full Fundamentals

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Source: SEC 10-Q filed Aug 11, 2026